Search of human proteins with 83641878

Search of human proteins with 83641878

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|83641878 presenilin associated, rhomboid-like isoform 2
preproprotein [Homo sapiens]
         (329 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|83641878 presenilin associated, rhomboid-like isoform 2 prepr...   687   0.0  
gi|20127652 presenilin associated, rhomboid-like isoform 1 prepr...   662   0.0  
gi|57242774 hypothetical protein LOC9703 [Homo sapiens]                30   2.3  
gi|13540517 endothelial differentiation, sphingolipid G-protein-...    30   2.3  
gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]      30   3.0  
gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens]           30   3.9  
gi|210147475 zinc finger protein 92 homolog [Homo sapiens]             30   3.9  

>gi|83641878 presenilin associated, rhomboid-like isoform 2
           preproprotein [Homo sapiens]
          Length = 329

 Score =  687 bits (1774), Expect = 0.0
 Identities = 329/329 (100%), Positives = 329/329 (100%)

Query: 1   MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV 60
           MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
Sbjct: 1   MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV 60

Query: 61  EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ 120
           EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
Sbjct: 61  EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ 120

Query: 121 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF 180
           YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
Sbjct: 121 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF 180

Query: 181 CLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTK 240
           CLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTK
Sbjct: 181 CLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTK 240

Query: 241 IPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGH 300
           IPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGH
Sbjct: 241 IPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGH 300

Query: 301 ELIWKNREPLVKIWHEIRTNGPKKGGGSK 329
           ELIWKNREPLVKIWHEIRTNGPKKGGGSK
Sbjct: 301 ELIWKNREPLVKIWHEIRTNGPKKGGGSK 329


>gi|20127652 presenilin associated, rhomboid-like isoform 1
           preproprotein [Homo sapiens]
          Length = 379

 Score =  662 bits (1709), Expect = 0.0
 Identities = 328/379 (86%), Positives = 328/379 (86%), Gaps = 50/379 (13%)

Query: 1   MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV 60
           MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
Sbjct: 1   MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV 60

Query: 61  EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ 120
           EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
Sbjct: 61  EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ 120

Query: 121 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF 180
           YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
Sbjct: 121 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF 180

Query: 181 CLWRVPSLQRTMIRYFTSNPAS-------------------------------------- 202
           CLWRVPSLQRTMIRYFTSNPAS                                      
Sbjct: 181 CLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNIL 240

Query: 203 ------------SVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIF 250
                        VISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIF
Sbjct: 241 GQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIF 300

Query: 251 LPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPL 310
           LPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPL
Sbjct: 301 LPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPL 360

Query: 311 VKIWHEIRTNGPKKGGGSK 329
           VKIWHEIRTNGPKKGGGSK
Sbjct: 361 VKIWHEIRTNGPKKGGGSK 379


>gi|57242774 hypothetical protein LOC9703 [Homo sapiens]
          Length = 2235

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 27/113 (23%), Positives = 53/113 (46%), Gaps = 14/113 (12%)

Query: 179 VFCLWRVPSLQRTMIRYFTSNP---ASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLA 235
           V  LW+V  L+   +  FT +    AS V  + ++ +G   T     ++G  G ++ ++ 
Sbjct: 568 VSLLWKV-DLKVEDMNLFTLSALVGASEVRLDTLTILGSAETS----TVGIQGLVLALVK 622

Query: 236 AV------CTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDH 282
           +V      C K P+    ++ L M + T  ++++++     AG+ L W   DH
Sbjct: 623 SVTEKMQPCCKAPDIPTPVLSLSMLSITYHSSIRSLEVQCGAGLTLLWSPPDH 675


>gi|13540517 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 8 [Homo sapiens]
          Length = 398

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 10/77 (12%)

Query: 200 PASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFL-------- 251
           P S VI    +Y GK+   RY P  G   A   V  AVC  I    LA++ +        
Sbjct: 10  PVSEVIVLHYNYTGKLRGARYQPGAGLR-ADAVVCLAVCAFIVLENLAVLLVLGRHPRFH 68

Query: 252 -PMFTFTAGNALKAIIA 267
            PMF       L  ++A
Sbjct: 69  APMFLLLGSLTLSDLLA 85


>gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]
          Length = 1992

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 7  AQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPR 63
          +QR     Q    S+GGRSC   +AV+ P      R N   +QK G  + P+K   R
Sbjct: 16 SQRNTAGAQPQDDSIGGRSCSSSSAVIVPQPEDPDRANTSERQKTG--QVPKKDNSR 70


>gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens]
          Length = 590

 Score = 29.6 bits (65), Expect = 3.9
 Identities = 37/137 (27%), Positives = 53/137 (38%), Gaps = 23/137 (16%)

Query: 155 INKW-WNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASSVISNFVSYVG 213
           +N+W   NL+         +A+N  V  L     L  +  RYF+       I+  ++Y  
Sbjct: 131 MNRWALGNLACDLWLAIDYVASNASVMNL-----LVISFDRYFS-------ITRPLTYRA 178

Query: 214 KVATGRYGPSLGASGAIMTVLAAVCT----------KIPEGRLAIIFLPMFTFTAGNALK 263
           K  T R G  +G +  I  VL A              +P G   I FL   T T G A+ 
Sbjct: 179 KRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIA 238

Query: 264 AIIAMDTAGMILGWKFF 280
           A     T   IL W+ +
Sbjct: 239 AFYMPVTIMTILYWRIY 255


>gi|210147475 zinc finger protein 92 homolog [Homo sapiens]
          Length = 416

 Score = 29.6 bits (65), Expect = 3.9
 Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 2/54 (3%)

Query: 40  GRRFNFFIQQKCGFRKAPRKVEPRR--SDPGTSGEAYKRSALIPPVEETVFYPS 91
           GRR N F  Q     + P K E  R  + PG++G     +A  PP   T   PS
Sbjct: 358 GRRANLFKHQAVHGARRPAKAETARRLAGPGSTGPGSAVAATSPPRPSTAARPS 411


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.456 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,657,125
Number of Sequences: 37866
Number of extensions: 604257
Number of successful extensions: 1286
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1281
Number of HSP's gapped (non-prelim): 9
length of query: 329
length of database: 18,247,518
effective HSP length: 103
effective length of query: 226
effective length of database: 14,347,320
effective search space: 3242494320
effective search space used: 3242494320
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.