Search of human proteins with 77812680

Search of human proteins with 77812680

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|77812680 inorganic pyrophosphatase 2 isoform 3 precursor
[Homo sapiens]
         (232 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|77812680 inorganic pyrophosphatase 2 isoform 3 precursor [Hom...   478   e-135
gi|77812678 inorganic pyrophosphatase 2 isoform 2 precursor [Hom...   330   6e-91
gi|77812684 inorganic pyrophosphatase 2 isoform 5 precursor [Hom...   330   8e-91
gi|29171702 inorganic pyrophosphatase 2 isoform 1 precursor [Hom...   330   8e-91
gi|77812682 inorganic pyrophosphatase 2 isoform 4 precursor [Hom...   246   2e-65
gi|11056044 pyrophosphatase 1 [Homo sapiens]                          197   6e-51
gi|57165424 cullin 4A isoform 1 [Homo sapiens]                         30   1.3  
gi|11140811 cullin 4A isoform 2 [Homo sapiens]                         30   1.3  
gi|88501736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform ...    29   3.0  
gi|27151736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform ...    29   3.0  
gi|116284392 mucin 2 precursor [Homo sapiens]                          28   8.7  
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              28   8.7  
gi|7657526 ribosomal protein S6 kinase polypeptide 6 [Homo sapiens]    28   8.7  
gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]       28   8.7  

>gi|77812680 inorganic pyrophosphatase 2 isoform 3 precursor [Homo
           sapiens]
          Length = 232

 Score =  478 bits (1231), Expect = e-135
 Identities = 232/232 (100%), Positives = 232/232 (100%)

Query: 1   MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
           MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
Sbjct: 1   MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60

Query: 61  SPFHDIPLKVNSKEILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDD 120
           SPFHDIPLKVNSKEILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDD
Sbjct: 61  SPFHDIPLKVNSKEILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDD 120

Query: 121 VKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKK 180
           VKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKK
Sbjct: 121 VKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKK 180

Query: 181 CNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 232
           CNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
Sbjct: 181 CNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 232


>gi|77812678 inorganic pyrophosphatase 2 isoform 2 precursor [Homo
           sapiens]
          Length = 305

 Score =  330 bits (846), Expect = 6e-91
 Identities = 158/159 (99%), Positives = 159/159 (100%)

Query: 74  EILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL 133
           +ILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL
Sbjct: 147 QILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL 206

Query: 134 NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI 193
           NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI
Sbjct: 207 NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI 266

Query: 194 SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 232
           SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
Sbjct: 267 SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 305



 Score =  153 bits (387), Expect = 1e-37
 Identities = 74/74 (100%), Positives = 74/74 (100%)

Query: 1  MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
          MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
Sbjct: 1  MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60

Query: 61 SPFHDIPLKVNSKE 74
          SPFHDIPLKVNSKE
Sbjct: 61 SPFHDIPLKVNSKE 74


>gi|77812684 inorganic pyrophosphatase 2 isoform 5 precursor [Homo
           sapiens]
          Length = 316

 Score =  330 bits (845), Expect = 8e-91
 Identities = 158/159 (99%), Positives = 159/159 (100%)

Query: 74  EILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL 133
           +ILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL
Sbjct: 158 KILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL 217

Query: 134 NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI 193
           NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI
Sbjct: 218 NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI 277

Query: 194 SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 232
           SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
Sbjct: 278 SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 316



 Score =  153 bits (387), Expect = 1e-37
 Identities = 74/74 (100%), Positives = 74/74 (100%)

Query: 1  MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
          MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
Sbjct: 1  MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60

Query: 61 SPFHDIPLKVNSKE 74
          SPFHDIPLKVNSKE
Sbjct: 61 SPFHDIPLKVNSKE 74


>gi|29171702 inorganic pyrophosphatase 2 isoform 1 precursor [Homo
           sapiens]
          Length = 334

 Score =  330 bits (845), Expect = 8e-91
 Identities = 158/159 (99%), Positives = 159/159 (100%)

Query: 74  EILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL 133
           +ILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL
Sbjct: 176 KILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL 235

Query: 134 NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI 193
           NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI
Sbjct: 236 NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI 295

Query: 194 SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 232
           SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
Sbjct: 296 SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 334



 Score =  153 bits (387), Expect = 1e-37
 Identities = 74/74 (100%), Positives = 74/74 (100%)

Query: 1  MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
          MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
Sbjct: 1  MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60

Query: 61 SPFHDIPLKVNSKE 74
          SPFHDIPLKVNSKE
Sbjct: 61 SPFHDIPLKVNSKE 74


>gi|77812682 inorganic pyrophosphatase 2 isoform 4 precursor [Homo
           sapiens]
          Length = 168

 Score =  246 bits (627), Expect = 2e-65
 Identities = 116/118 (98%), Positives = 117/118 (99%)

Query: 115 FHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWK 174
           F +IDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWK
Sbjct: 51  FFNIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWK 110

Query: 175 ALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 232
           ALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
Sbjct: 111 ALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 168



 Score =  107 bits (267), Expect = 9e-24
 Identities = 52/52 (100%), Positives = 52/52 (100%)

Query: 1  MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFF 52
          MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFF
Sbjct: 1  MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFF 52


>gi|11056044 pyrophosphatase 1 [Homo sapiens]
          Length = 289

 Score =  197 bits (501), Expect = 6e-51
 Identities = 86/139 (61%), Positives = 118/139 (84%)

Query: 74  EILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL 133
           ++ + GE+I VK+LGILA+IDEGETDWK+IAIN +DP+A+ ++DI+DVK+ KPGYLEAT+
Sbjct: 128 KVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKPGYLEATV 187

Query: 134 NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI 193
           +WFR YKVPDGKPEN+FAFN EFK+K FA+++IKSTH  WKAL+ KK NG  I+C N  +
Sbjct: 188 DWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGISCMNTTL 247

Query: 194 SDSPFRCTQEEARSLVESV 212
           S+SPF+C  + AR++V+++
Sbjct: 248 SESPFKCDPDAARAIVDAL 266



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 22/37 (59%), Positives = 26/37 (70%)

Query: 32 MALYHTEERGQPCSQNYRLFFKNVTGHYISPFHDIPL 68
          M+ + TEER  P S  YR+F KN  G YISPFHDIP+
Sbjct: 1  MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPI 37


>gi|57165424 cullin 4A isoform 1 [Homo sapiens]
          Length = 759

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 9/73 (12%)

Query: 102 LIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFR------LYKVPDGKPE---NQFAF 152
           L+ +  N+ +   F +I      +   L  TL          L K P GK     ++F F
Sbjct: 597 LVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIF 656

Query: 153 NGEFKNKAFALEV 165
           NGEFK+K F +++
Sbjct: 657 NGEFKHKLFRIKI 669


>gi|11140811 cullin 4A isoform 2 [Homo sapiens]
          Length = 659

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 9/73 (12%)

Query: 102 LIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFR------LYKVPDGKPE---NQFAF 152
           L+ +  N+ +   F +I      +   L  TL          L K P GK     ++F F
Sbjct: 497 LVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIF 556

Query: 153 NGEFKNKAFALEV 165
           NGEFK+K F +++
Sbjct: 557 NGEFKHKLFRIKI 569


>gi|88501736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform a
           [Homo sapiens]
          Length = 277

 Score = 29.3 bits (64), Expect = 3.0
 Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 8/53 (15%)

Query: 119 DDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQ 171
           DD+KK    Y    L W      PD  P+N+     +FK  A A EV+   H+
Sbjct: 17  DDIKK---AYRRKALQWH-----PDKNPDNKEFAEKKFKEVAEAYEVLSDKHK 61


>gi|27151736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform b
           [Homo sapiens]
          Length = 324

 Score = 29.3 bits (64), Expect = 3.0
 Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 8/53 (15%)

Query: 119 DDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQ 171
           DD+KK    Y    L W      PD  P+N+     +FK  A A EV+   H+
Sbjct: 17  DDIKK---AYRRKALQWH-----PDKNPDNKEFAEKKFKEVAEAYEVLSDKHK 61


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 27.7 bits (60), Expect = 8.7
 Identities = 17/50 (34%), Positives = 21/50 (42%), Gaps = 4/50 (8%)

Query: 172  CWKALLMKKCNGGA----INCTNVQISDSPFRCTQEEARSLVESVSSSPN 217
            C K +LM  C+G      +     Q  D    C +EE  S  E V S PN
Sbjct: 5089 CTKTVLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEEKTSQREVVLSCPN 5138


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 27.7 bits (60), Expect = 8.7
 Identities = 17/50 (34%), Positives = 21/50 (42%), Gaps = 4/50 (8%)

Query: 172  CWKALLMKKCNGGA----INCTNVQISDSPFRCTQEEARSLVESVSSSPN 217
            C K +LM  C+G      +     Q  D    C +EE  S  E V S PN
Sbjct: 2549 CTKTVLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEEKTSQREVVLSCPN 2598


>gi|7657526 ribosomal protein S6 kinase polypeptide 6 [Homo sapiens]
          Length = 745

 Score = 27.7 bits (60), Expect = 8.7
 Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 12/68 (17%)

Query: 119 DDVKKFKPGYLEATLNWFRLYK--------VPDGKPENQFAFNGEFKNK----AFALEVI 166
           + V++ K     A ++W +LYK           GKP++ F F+ EF  K    +  L   
Sbjct: 319 EGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPEFTAKTPKDSPGLPAS 378

Query: 167 KSTHQCWK 174
            + HQ +K
Sbjct: 379 ANAHQLFK 386


>gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]
          Length = 631

 Score = 27.7 bits (60), Expect = 8.7
 Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 6/68 (8%)

Query: 37  TEERGQPCSQNYRLFFKNVTGHYISPFHDIPLKVNSKEILSCGEVIHVKILGI----LAL 92
           ++E   P   +Y+L  KN+   +  P   + ++ +   ++SCGE    K+LG+    + L
Sbjct: 331 SKESLSPAKFDYKL--KNIFRLHELPVSCVSMQPHKDILVSCGEDRLWKVLGLPKCNVLL 388

Query: 93  IDEGETDW 100
              G TDW
Sbjct: 389 TGFGHTDW 396


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,184,364
Number of Sequences: 37866
Number of extensions: 410862
Number of successful extensions: 972
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 961
Number of HSP's gapped (non-prelim): 19
length of query: 232
length of database: 18,247,518
effective HSP length: 99
effective length of query: 133
effective length of database: 14,498,784
effective search space: 1928338272
effective search space used: 1928338272
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.