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Search of human proteins with 7706095
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706095 RAS-like, family 12 protein [Homo sapiens]
(266 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706095 RAS-like, family 12 protein [Homo sapiens] 525 e-149
gi|14249704 RAS-like, estrogen-regulated, growth inhibitor [Homo... 132 3e-31
gi|5902050 Ras-like without CAAX 1 [Homo sapiens] 124 7e-29
gi|4506533 Ras-like without CAAX 2 [Homo sapiens] 124 1e-28
gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapi... 108 4e-24
gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] 105 5e-23
gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform... 103 1e-22
gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] 103 2e-22
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 102 3e-22
gi|145386506 muscle RAS oncogene homolog [Homo sapiens] 102 3e-22
gi|145386562 muscle RAS oncogene homolog [Homo sapiens] 102 3e-22
gi|13027612 RAS-like family 11 member B [Homo sapiens] 98 7e-21
gi|45592963 RAS-like, family 11, member A [Homo sapiens] 97 1e-20
gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] 96 3e-20
gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] 96 3e-20
gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] 96 4e-20
gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] 96 4e-20
gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens] 91 8e-19
gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] 89 3e-18
gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog ... 89 4e-18
gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog is... 89 4e-18
gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo ... 89 5e-18
gi|21703367 Di-Ras2 [Homo sapiens] 88 7e-18
gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Hom... 86 3e-17
gi|5032041 Ras homolog enriched in brain [Homo sapiens] 86 3e-17
gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens] 86 4e-17
gi|33946329 ras related v-ral simian leukemia viral oncogene hom... 85 7e-17
gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog i... 84 1e-16
gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens] 84 2e-16
gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens] 82 4e-16
>gi|7706095 RAS-like, family 12 protein [Homo sapiens]
Length = 266
Score = 525 bits (1353), Expect = e-149
Identities = 266/266 (100%), Positives = 266/266 (100%)
Query: 1 MSSVFGKPRAGSGPQSAPLEVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSE 60
MSSVFGKPRAGSGPQSAPLEVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSE
Sbjct: 1 MSSVFGKPRAGSGPQSAPLEVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSE 60
Query: 61 ETVDHQPVHLRVMDTADLDTPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHA 120
ETVDHQPVHLRVMDTADLDTPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHA
Sbjct: 61 ETVDHQPVHLRVMDTADLDTPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHA 120
Query: 121 KETQRSIPALLLGNKLDMAQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAV 180
KETQRSIPALLLGNKLDMAQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAV
Sbjct: 121 KETQRSIPALLLGNKLDMAQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAV 180
Query: 181 REARRELEKSPLTRPLFISEERALPHQAPLTARHGLASCTFNTLSTINLKEMPTVAQAKL 240
REARRELEKSPLTRPLFISEERALPHQAPLTARHGLASCTFNTLSTINLKEMPTVAQAKL
Sbjct: 181 REARRELEKSPLTRPLFISEERALPHQAPLTARHGLASCTFNTLSTINLKEMPTVAQAKL 240
Query: 241 VTVKSSRAQSKRKAPTLTLLKGFKIF 266
VTVKSSRAQSKRKAPTLTLLKGFKIF
Sbjct: 241 VTVKSSRAQSKRKAPTLTLLKGFKIF 266
>gi|14249704 RAS-like, estrogen-regulated, growth inhibitor [Homo
sapiens]
Length = 199
Score = 132 bits (332), Expect = 3e-31
Identities = 69/166 (41%), Positives = 96/166 (57%), Gaps = 2/166 (1%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
EV LAI GR G GKSAL V+FLTKRFI EYDP LE TY + T+D + V + ++DTA +
Sbjct: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
Query: 80 TPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDMA 139
E ++ W F++VY + R SF+ +L K +++ +L+GNK D+
Sbjct: 66 DTIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKK--PKNVTLILVGNKADLD 123
Query: 140 QYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARR 185
RQV+ EG LA C F+E SAC ++ +F+E RE RR
Sbjct: 124 HSRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRR 169
>gi|5902050 Ras-like without CAAX 1 [Homo sapiens]
Length = 219
Score = 124 bits (312), Expect = 7e-29
Identities = 67/182 (36%), Positives = 104/182 (57%), Gaps = 4/182 (2%)
Query: 12 SGPQSAPLEVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLR 71
S P E L +LG G GKSA+T++F++ RF ++DP +ED Y +D +P +L
Sbjct: 13 SSPAGLSREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLD 72
Query: 72 VMDTA-DLDTPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPAL 130
++DTA + ++Y+ F++ YS+ R+SF + +L ++ P +
Sbjct: 73 ILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQL--IYRVRRTDDTPVV 130
Query: 131 LLGNKLDMAQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARRELEKS 190
L+GNK D+ Q RQVTK EG+ALA F C FFE SA + ++ VFH VRE RR+ +++
Sbjct: 131 LVGNKSDLKQLRQVTKEEGLALAREFSCPFFETSAAYRY-YIDDVFHALVREIRRKEKEA 189
Query: 191 PL 192
L
Sbjct: 190 VL 191
>gi|4506533 Ras-like without CAAX 2 [Homo sapiens]
Length = 217
Score = 124 bits (310), Expect = 1e-28
Identities = 64/168 (38%), Positives = 104/168 (61%), Gaps = 4/168 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTA-DL 78
E + +LG G GKSA+T++F++ +F +DP +ED Y ++ +D++P +L ++DTA
Sbjct: 20 EYKVVMLGAGGVGKSAMTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAGQA 79
Query: 79 DTPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
+ E+Y+ F++ YSV RQSF ++ + EL+ + T IP +L+GNK+D+
Sbjct: 80 EFTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELI-FQVRHTY-EIPLVLVGNKIDL 137
Query: 139 AQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARRE 186
Q+RQV+ EG++LA + C FFE SA L F + FH VRE R++
Sbjct: 138 EQFRQVSTEEGLSLAQEYNCGFFETSAALRF-CIDDAFHGLVREIRKK 184
>gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo
sapiens]
Length = 218
Score = 108 bits (271), Expect = 4e-24
Identities = 69/199 (34%), Positives = 108/199 (54%), Gaps = 13/199 (6%)
Query: 6 GKPRAGS-GPQSAPLEVN--LAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEET 62
G+PR G GP P L ++G G GKSALT++F+ F+S+YDP +ED+Y+ +
Sbjct: 12 GRPRGGGPGPGDPPPSETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICS 71
Query: 63 VDHQPVHLRVMDTADLDT-PRNCERYLNWAHAFLVVYSVDSRQSFDS-SSSYLELLALHA 120
VD P L ++DTA + E+Y+ H FL+V++++ RQSF+ + ++L +
Sbjct: 72 VDGIPARLDILDTAGQEEFGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKD 131
Query: 121 KETQRSIPALLLGNKLDMAQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAV 180
++ P +L+GNK D+ RQV ++E A +FE SA L +V F + V
Sbjct: 132 RD---DFPVVLVGNKADLESQRQVPRSEASAFGASHHVAYFEASAKLRL-NVDEAFEQLV 187
Query: 181 REARR----ELEKSPLTRP 195
R R+ EL SP + P
Sbjct: 188 RAVRKYQEQELPPSPPSAP 206
>gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 105 bits (261), Expect = 5e-23
Identities = 62/164 (37%), Positives = 95/164 (57%), Gaps = 4/164 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
E + +LG G GKSALTV+F+T FI +YDP +ED Y E VD P L ++DTA +
Sbjct: 3 EYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62
Query: 80 TPRNC-ERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
+ + Y+ F++VYS+ ++QSF + + + K ++ +P +L+GNK+D+
Sbjct: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQI-IRVKRYEK-VPVILVGNKVDL 120
Query: 139 AQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVRE 182
R+V+ +EG ALA +GC F E SA V +F E VR+
Sbjct: 121 ESEREVSSSEGRALAEEWGCPFMETSA-KSKTMVDELFAEIVRQ 163
>gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform a
[Homo sapiens]
Length = 204
Score = 103 bits (258), Expect = 1e-22
Identities = 66/190 (34%), Positives = 103/190 (54%), Gaps = 10/190 (5%)
Query: 9 RAGSGPQSAPLEVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPV 68
R GSG + + L ++G G GKSALT++F+ F+++YDP +ED+Y+ + +D +
Sbjct: 7 RDGSGQE----KYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAA 62
Query: 69 HLRVMDTADLDT-PRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSI 127
L ++DTA + E+Y+ FL+V+SV R SF+ + + L K+ +
Sbjct: 63 RLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQI-LRVKD-RDEF 120
Query: 128 PALLLGNKLDMAQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARR-- 185
P +L+GNK D+ RQVT+ EG LA + + E SA + +V FHE VR R+
Sbjct: 121 PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRM-NVDQAFHELVRVIRKFQ 179
Query: 186 ELEKSPLTRP 195
E E P P
Sbjct: 180 EQECPPSPEP 189
>gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 103 bits (257), Expect = 2e-22
Identities = 62/164 (37%), Positives = 94/164 (57%), Gaps = 4/164 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
E + +LG G GKSALTV+F+T FI +YDP +ED Y E VD P L ++DTA +
Sbjct: 3 EYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62
Query: 80 TPRNC-ERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
+ + Y+ F++VYS+ ++QSF + + + K ++ +P +L+GNK+D+
Sbjct: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQI-VRVKRYEK-VPLILVGNKVDL 120
Query: 139 AQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVRE 182
R+V +EG ALA +GC F E SA V +F E VR+
Sbjct: 121 EPEREVMSSEGRALAQEWGCPFMETSA-KSKSMVDELFAEIVRQ 163
>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 102 bits (255), Expect = 3e-22
Identities = 62/164 (37%), Positives = 94/164 (57%), Gaps = 4/164 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
E + +LG G GKSALTV+F+T FI +YDP +ED Y E VD P L ++DTA +
Sbjct: 3 EYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62
Query: 80 TPRNC-ERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
+ + Y+ F++VYS+ ++QSF + + + K +R +P +L+GNK+D+
Sbjct: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQI-IRVKRYER-VPMILVGNKVDL 120
Query: 139 AQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVRE 182
R+V+ EG ALA + C F E SA + V +F E VR+
Sbjct: 121 EGEREVSYGEGKALAEEWSCPFMETSA-KNKASVDELFAEIVRQ 163
>gi|145386506 muscle RAS oncogene homolog [Homo sapiens]
Length = 208
Score = 102 bits (254), Expect = 3e-22
Identities = 60/170 (35%), Positives = 98/170 (57%), Gaps = 4/170 (2%)
Query: 23 LAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLDT-P 81
L ++G G GKSALT++F K F+ +YDP +ED+Y +D+Q L V+DTA +
Sbjct: 16 LVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFS 75
Query: 82 RNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDMAQY 141
E+Y+ FL+VYSV + SF+ + +L+ L K+ + S P +L+ NK+D+
Sbjct: 76 AMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLI-LRVKD-RESFPMILVANKVDLMHL 133
Query: 142 RQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARREL-EKS 190
R++T+ +G +A + + E SA +V FH+ VR R+++ EKS
Sbjct: 134 RKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQIPEKS 183
>gi|145386562 muscle RAS oncogene homolog [Homo sapiens]
Length = 208
Score = 102 bits (254), Expect = 3e-22
Identities = 60/170 (35%), Positives = 98/170 (57%), Gaps = 4/170 (2%)
Query: 23 LAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLDT-P 81
L ++G G GKSALT++F K F+ +YDP +ED+Y +D+Q L V+DTA +
Sbjct: 16 LVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFS 75
Query: 82 RNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDMAQY 141
E+Y+ FL+VYSV + SF+ + +L+ L K+ + S P +L+ NK+D+
Sbjct: 76 AMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLI-LRVKD-RESFPMILVANKVDLMHL 133
Query: 142 RQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARREL-EKS 190
R++T+ +G +A + + E SA +V FH+ VR R+++ EKS
Sbjct: 134 RKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQIPEKS 183
>gi|13027612 RAS-like family 11 member B [Homo sapiens]
Length = 248
Score = 98.2 bits (243), Expect = 7e-21
Identities = 56/179 (31%), Positives = 94/179 (52%), Gaps = 13/179 (7%)
Query: 21 VNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLDT 80
V +A++G G GK+AL V+FLTKRFI +Y+ N + Y+ + ++ + + L+V DT +
Sbjct: 34 VKIAVVGASGVGKTALVVRFLTKRFIGDYERNAGNLYTRQVQIEGETLALQVQDTPGIQV 93
Query: 81 PRN---CERYLN----WAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQ--RSIPALL 131
N C LN WA A ++V+S+ +S++ S L H ++ +P ++
Sbjct: 94 HENSLSCSEQLNRCIRWADAVVIVFSITDYKSYELISQ----LHQHVQQLHLGTRLPVVV 149
Query: 132 LGNKLDMAQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARRELEKS 190
+ NK D+ +QV G+ LA GC F+EVS ++ V FH +E + + S
Sbjct: 150 VANKADLLHIKQVDPQLGLQLASMLGCSFYEVSVSENYNDVYSAFHVLCKEVSHKQQPS 208
>gi|45592963 RAS-like, family 11, member A [Homo sapiens]
Length = 242
Score = 97.4 bits (241), Expect = 1e-20
Identities = 60/180 (33%), Positives = 90/180 (50%), Gaps = 18/180 (10%)
Query: 18 PLEVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTAD 77
P ++ LA+LG GKSA+ V+FLTKRFI +Y+PN YS V+ + L++ DT
Sbjct: 25 PKDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPG 84
Query: 78 -----------LDTPRNCERYLNWAHAFLVVYSVDSRQSFDS-SSSYLELLALHAKETQR 125
+D+ C + WA FL+VYS+ S+ S Y + +H
Sbjct: 85 GVQIQDSLPQVVDSLSKC---VQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVH---PDS 138
Query: 126 SIPALLLGNKLDMAQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARR 185
P +++GNK D+ RQV +G+ LA G LF E+S ++E V VF +E +
Sbjct: 139 KAPVIIVGNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSK 198
>gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 95.9 bits (237), Expect = 3e-20
Identities = 59/169 (34%), Positives = 94/169 (55%), Gaps = 5/169 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
E L +LG G GKSALTV+F+ F+ +YDP +ED+Y + VD Q L ++DTA +
Sbjct: 3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTE 62
Query: 80 T-PRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
+ Y+ F +VYS+ ++ +F+ E + L K+T+ +P +L+GNK D+
Sbjct: 63 QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQI-LRVKDTE-DVPMILVGNKCDL 120
Query: 139 AQYRQVTKAEGVALAGRF-GCLFFEVSACLDFEHVQHVFHEAVREARRE 186
R V K +G LA ++ C F E SA +V +F++ VR+ R+
Sbjct: 121 EDERVVGKEQGQNLARQWCNCAFLESSAKSKI-NVNEIFYDLVRQINRK 168
>gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 95.9 bits (237), Expect = 3e-20
Identities = 59/169 (34%), Positives = 94/169 (55%), Gaps = 5/169 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
E L +LG G GKSALTV+F+ F+ +YDP +ED+Y + VD Q L ++DTA +
Sbjct: 3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTE 62
Query: 80 T-PRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
+ Y+ F +VYS+ ++ +F+ E + L K+T+ +P +L+GNK D+
Sbjct: 63 QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQI-LRVKDTE-DVPMILVGNKCDL 120
Query: 139 AQYRQVTKAEGVALAGRF-GCLFFEVSACLDFEHVQHVFHEAVREARRE 186
R V K +G LA ++ C F E SA +V +F++ VR+ R+
Sbjct: 121 EDERVVGKEQGQNLARQWCNCAFLESSAKSKI-NVNEIFYDLVRQINRK 168
>gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 95.5 bits (236), Expect = 4e-20
Identities = 59/169 (34%), Positives = 93/169 (55%), Gaps = 5/169 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
E L +LG G GKSALTV+F+ F+ +YDP +ED+Y + VD Q L ++DTA +
Sbjct: 3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTE 62
Query: 80 T-PRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
+ Y+ F +VYS+ ++ +F+ E + L K+T +P +L+GNK D+
Sbjct: 63 QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQI-LRVKDTD-DVPMILVGNKCDL 120
Query: 139 AQYRQVTKAEGVALAGRF-GCLFFEVSACLDFEHVQHVFHEAVREARRE 186
R V K +G LA ++ C F E SA +V +F++ VR+ R+
Sbjct: 121 EDERVVGKEQGQNLARQWNNCAFLESSAKSKI-NVNEIFYDLVRQINRK 168
>gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 95.5 bits (236), Expect = 4e-20
Identities = 59/169 (34%), Positives = 93/169 (55%), Gaps = 5/169 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
E L +LG G GKSALTV+F+ F+ +YDP +ED+Y + VD Q L ++DTA +
Sbjct: 3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTE 62
Query: 80 T-PRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
+ Y+ F +VYS+ ++ +F+ E + L K+T +P +L+GNK D+
Sbjct: 63 QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQI-LRVKDTD-DVPMILVGNKCDL 120
Query: 139 AQYRQVTKAEGVALAGRF-GCLFFEVSACLDFEHVQHVFHEAVREARRE 186
R V K +G LA ++ C F E SA +V +F++ VR+ R+
Sbjct: 121 EDERVVGKEQGQNLARQWNNCAFLESSAKSKI-NVNEIFYDLVRQINRK 168
>gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens]
Length = 188
Score = 91.3 bits (225), Expect = 8e-19
Identities = 55/171 (32%), Positives = 92/171 (53%), Gaps = 5/171 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
E L ++G G GKSALT++ + F+ EYDP +ED+Y + +D + L ++DTA +
Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQE 62
Query: 80 T-PRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
++Y+ FL V+++++ +SF+ Y E + K+++ +P +L+GNK D+
Sbjct: 63 EYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIK-RVKDSE-DVPMVLVGNKCDL 120
Query: 139 AQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARRELEK 189
R V + LA +G F E SA + V F+ VRE R+ EK
Sbjct: 121 PS-RTVDTKQAQDLARSYGIPFIETSA-KTRQGVDDAFYTLVREIRKHKEK 169
>gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens]
Length = 189
Score = 89.4 bits (220), Expect = 3e-18
Identities = 53/167 (31%), Positives = 91/167 (54%), Gaps = 5/167 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
E L ++G G GKSALT++ + F+ EYDP +ED+Y + +D + L ++DTA +
Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQE 62
Query: 80 T-PRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
++Y+ FL V+++++ +SF+ Y E + K+++ +P +L+GNK D+
Sbjct: 63 EYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIK-RVKDSE-DVPMVLVGNKCDL 120
Query: 139 AQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARR 185
R V + LA +G F E SA + V+ F+ VRE R+
Sbjct: 121 PS-RTVDTKQAQDLARSYGIPFIETSA-KTRQRVEDAFYTLVREIRQ 165
>gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 89.0 bits (219), Expect = 4e-18
Identities = 53/167 (31%), Positives = 91/167 (54%), Gaps = 5/167 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
E L ++G G GKSALT++ + F+ EYDP +ED+Y + +D + L ++DTA +
Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQE 62
Query: 80 T-PRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
++Y+ FL V+++++ +SF+ Y E + K++ +P +L+GNK D+
Sbjct: 63 EYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIK-RVKDSD-DVPMVLVGNKCDL 120
Query: 139 AQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARR 185
A R V + LA +G + E SA + V+ F+ VRE R+
Sbjct: 121 AA-RTVESRQAQDLARSYGIPYIETSA-KTRQGVEDAFYTLVREIRQ 165
>gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 89.0 bits (219), Expect = 4e-18
Identities = 53/167 (31%), Positives = 91/167 (54%), Gaps = 5/167 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
E L ++G G GKSALT++ + F+ EYDP +ED+Y + +D + L ++DTA +
Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQE 62
Query: 80 T-PRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
++Y+ FL V+++++ +SF+ Y E + K++ +P +L+GNK D+
Sbjct: 63 EYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIK-RVKDSD-DVPMVLVGNKCDL 120
Query: 139 AQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARR 185
A R V + LA +G + E SA + V+ F+ VRE R+
Sbjct: 121 AA-RTVESRQAQDLARSYGIPYIETSA-KTRQGVEDAFYTLVREIRQ 165
>gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo
sapiens]
Length = 206
Score = 88.6 bits (218), Expect = 5e-18
Identities = 52/161 (32%), Positives = 88/161 (54%), Gaps = 3/161 (1%)
Query: 25 ILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTA-DLDTPRN 83
++G G GKSALT++F+ F+ +Y+P D+Y + +D + V + ++DTA D
Sbjct: 19 MVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAI 78
Query: 84 CERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDMAQYRQ 143
+ Y FL+V+S+ +SF +++ + E + L K + IP L++GNK D+ + RQ
Sbjct: 79 RDNYFRSGEGFLLVFSITEHESFTATAEFREQI-LRVKAEEDKIPLLVVGNKSDLEERRQ 137
Query: 144 VTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREAR 184
V E + A +G + E SA +V VF + +RE R
Sbjct: 138 VPVEEARSKAEEWGVQYVETSA-KTRANVDKVFFDLMREIR 177
>gi|21703367 Di-Ras2 [Homo sapiens]
Length = 199
Score = 88.2 bits (217), Expect = 7e-18
Identities = 56/167 (33%), Positives = 86/167 (51%), Gaps = 3/167 (1%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMD-TADL 78
+ +A+ G G GKS+L ++F+ F Y P +EDTY + D L++ D T
Sbjct: 7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSH 66
Query: 79 DTPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
P ++ HAF++VYS+ SRQS + E + K SIP +L+GNK D
Sbjct: 67 QFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQIC-EIKGDVESIPIMLVGNKCDE 125
Query: 139 AQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARR 185
+ R+V +E ALA + C F E SA L+ +V+ +F E + +R
Sbjct: 126 SPSREVQSSEAEALARTWKCAFMETSAKLN-HNVKELFQELLNLEKR 171
>gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Homo
sapiens]
Length = 189
Score = 86.3 bits (212), Expect = 3e-17
Identities = 53/167 (31%), Positives = 90/167 (53%), Gaps = 5/167 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
E L ++G G GKSALT++ + F+ EYDP +ED+Y + +D + L ++DTA +
Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQE 62
Query: 80 T-PRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
++Y+ FL V+++++ +SF + Y E + K++ +P +L+GNK D+
Sbjct: 63 EYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIK-RVKDSD-DVPMVLVGNKCDL 120
Query: 139 AQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARR 185
R V + LA +G F E SA + V+ F+ VRE R+
Sbjct: 121 PT-RTVDTKQAHELAKSYGIPFIETSA-KTRQGVEDAFYTLVREIRQ 165
>gi|5032041 Ras homolog enriched in brain [Homo sapiens]
Length = 184
Score = 86.3 bits (212), Expect = 3e-17
Identities = 61/180 (33%), Positives = 96/180 (53%), Gaps = 20/180 (11%)
Query: 14 PQSAPLEVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVM 73
PQS ++ AILG R GKS+LT++F+ +F+ YDP +E+T++ TV+ Q HL+++
Sbjct: 2 PQSKSRKI--AILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLV 59
Query: 74 DTADLDT----PRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQR---- 125
DTA D P+ +N +++VYSV S +SF+ + +H K
Sbjct: 60 DTAGQDEYSIFPQTYSIDIN---GYILVYSVTSIKSFE------VIKVIHGKLLDMVGKV 110
Query: 126 SIPALLLGNKLDMAQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARR 185
IP +L+GNK D+ R ++ EG ALA + F E SA + + VF + EA +
Sbjct: 111 QIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSA-KENQTAVDVFRRIILEAEK 169
>gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens]
Length = 183
Score = 85.5 bits (210), Expect = 4e-17
Identities = 55/164 (33%), Positives = 85/164 (51%), Gaps = 4/164 (2%)
Query: 23 LAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLDTPR 82
+ ILG R GK++L +F+ F YDP +E+TYS T+ HL ++DTA D
Sbjct: 9 VVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEYS 68
Query: 83 NCE-RYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDMAQY 141
++ H +++VYSV S SF S + LH + +P +L+GNK D++
Sbjct: 69 ILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQ--KLHEGHGKTRVPVVLVGNKADLSPE 126
Query: 142 RQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARR 185
R+V EG LA +G F E SA + + Q +F + ++E R
Sbjct: 127 REVQAVEGKKLAESWGATFMESSA-RENQLTQGIFTKVIQEIAR 169
>gi|33946329 ras related v-ral simian leukemia viral oncogene
homolog A [Homo sapiens]
Length = 206
Score = 84.7 bits (208), Expect = 7e-17
Identities = 55/168 (32%), Positives = 93/168 (55%), Gaps = 5/168 (2%)
Query: 25 ILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTA-DLDTPRN 83
++G G GKSALT++F+ F+ +Y+P D+Y + +D + V + ++DTA D
Sbjct: 19 MVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAI 78
Query: 84 CERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDMAQYRQ 143
+ Y FL V+S+ +SF +++ + E + L KE + ++P LL+GNK D+ RQ
Sbjct: 79 RDNYFRSGEGFLCVFSITEMESFAATADFREQI-LRVKEDE-NVPFLLVGNKSDLEDKRQ 136
Query: 144 VTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREAR-RELEKS 190
V+ E A ++ + E SA +V VF + +RE R R++E S
Sbjct: 137 VSVEEAKNRAEQWNVNYVETSA-KTRANVDKVFFDLMREIRARKMEDS 183
>gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 2 [Homo sapiens]
Length = 170
Score = 84.3 bits (207), Expect = 1e-16
Identities = 47/147 (31%), Positives = 81/147 (55%), Gaps = 4/147 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
E L ++G G GKSALT++ + F+ EYDP +ED+Y + +D + L ++DTA +
Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQE 62
Query: 80 T-PRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
++Y+ FL V+++++ +SF+ Y E + K++ +P +L+GNK D+
Sbjct: 63 EYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIK-RVKDSD-DVPMVLVGNKCDL 120
Query: 139 AQYRQVTKAEGVALAGRFGCLFFEVSA 165
A R V + LA +G + E SA
Sbjct: 121 AA-RTVESRQAQDLARSYGIPYIETSA 146
>gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens]
Length = 298
Score = 83.6 bits (205), Expect = 2e-16
Identities = 68/201 (33%), Positives = 100/201 (49%), Gaps = 15/201 (7%)
Query: 23 LAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTAD---LD 79
+ +LG G GK++L F K+ ++ ED Y TVD + L V+DT + LD
Sbjct: 83 VVLLGDPGVGKTSLASLFAGKQERDLHEQLGEDVYERTLTVDGEDTTLVVVDTWEAEKLD 142
Query: 80 TPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRS--IPALLLGNKLD 137
+ E L A+++VYS+ R SF+S+S L + + T ++ +P +L+GNK D
Sbjct: 143 KSWSQESCLQGGSAYVIVYSIADRGSFESASE----LRIQLRRTHQADHVPIILVGNKAD 198
Query: 138 MAQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARRELEKS-----PL 192
+A+ R+V+ EG A A F C F E SA L +V +F VR+ R S P
Sbjct: 199 LARCREVSVEEGRACAVVFDCKFIETSATLQ-HNVAELFEGVVRQLRLRRRDSAAKEPPA 257
Query: 193 TRPLFISEERALPHQAPLTAR 213
R +RA A LTAR
Sbjct: 258 PRRPASLAQRARRFLARLTAR 278
>gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens]
Length = 198
Score = 82.4 bits (202), Expect = 4e-16
Identities = 54/170 (31%), Positives = 89/170 (52%), Gaps = 5/170 (2%)
Query: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMD-TADL 78
+ + + G G GKS+L ++F+ F Y P +EDTY + D L++ D T
Sbjct: 7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSH 66
Query: 79 DTPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
P ++ HAF++V+SV S+QS + +L+ + K + IP +L+GNK D
Sbjct: 67 QFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLI-VQIKGSVEDIPVMLVGNKCDE 125
Query: 139 AQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVR-EARREL 187
Q R+V E A+A + C F E SA +++ +V+ +F E + E RR +
Sbjct: 126 TQ-REVDTREAQAVAQEWKCAFMETSAKMNY-NVKELFQELLTLETRRNM 173
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,337,075
Number of Sequences: 37866
Number of extensions: 381190
Number of successful extensions: 1314
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 133
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 1019
Number of HSP's gapped (non-prelim): 203
length of query: 266
length of database: 18,247,518
effective HSP length: 100
effective length of query: 166
effective length of database: 14,460,918
effective search space: 2400512388
effective search space used: 2400512388
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.