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Search of human proteins with 7669546
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]
(311 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] 641 0.0
gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] 641 0.0
gi|7669548 tachykinin receptor 3 [Homo sapiens] 430 e-121
gi|157426873 tachykinin receptor 2 [Homo sapiens] 358 4e-99
gi|223633971 G protein-coupled receptor 83 [Homo sapiens] 179 4e-45
gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] 158 5e-39
gi|4758474 G protein-coupled receptor 10 [Homo sapiens] 150 1e-36
gi|157738685 G protein-coupled receptor 103 [Homo sapiens] 141 8e-34
gi|222080109 orexin receptor 2 [Homo sapiens] 138 5e-33
gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens] 138 5e-33
gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens] 138 5e-33
gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens] 138 5e-33
gi|21426829 prokineticin receptor 2 [Homo sapiens] 136 3e-32
gi|20373179 G protein-coupled receptor 73 [Homo sapiens] 135 4e-32
gi|4502455 bombesin-like receptor 3 [Homo sapiens] 133 2e-31
gi|222080095 orexin receptor 1 [Homo sapiens] 130 1e-30
gi|63477962 opioid receptor, delta 1 [Homo sapiens] 130 2e-30
gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 130 2e-30
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens] 127 2e-29
gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] 126 3e-29
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens] 125 5e-29
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens] 125 5e-29
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] 125 5e-29
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens] 125 5e-29
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens] 125 5e-29
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens] 125 5e-29
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens] 125 5e-29
gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens] 125 5e-29
gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens] 125 5e-29
gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens] 125 5e-29
>gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]
Length = 311
Score = 641 bits (1654), Expect = 0.0
Identities = 311/311 (100%), Positives = 311/311 (100%)
Query: 1 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH 60
MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH
Sbjct: 1 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH 60
Query: 61 KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI 120
KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI
Sbjct: 61 KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI 120
Query: 121 YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC 180
YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC
Sbjct: 121 YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC 180
Query: 181 MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV 240
MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV
Sbjct: 181 MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV 240
Query: 241 SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY 300
SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY
Sbjct: 241 SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY 300
Query: 301 NPIIYCCLNDR 311
NPIIYCCLNDR
Sbjct: 301 NPIIYCCLNDR 311
>gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]
Length = 407
Score = 641 bits (1654), Expect = 0.0
Identities = 311/311 (100%), Positives = 311/311 (100%)
Query: 1 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH 60
MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH
Sbjct: 1 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH 60
Query: 61 KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI 120
KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI
Sbjct: 61 KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI 120
Query: 121 YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC 180
YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC
Sbjct: 121 YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC 180
Query: 181 MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV 240
MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV
Sbjct: 181 MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV 240
Query: 241 SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY 300
SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY
Sbjct: 241 SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY 300
Query: 301 NPIIYCCLNDR 311
NPIIYCCLNDR
Sbjct: 301 NPIIYCCLNDR 311
>gi|7669548 tachykinin receptor 3 [Homo sapiens]
Length = 465
Score = 430 bits (1105), Expect = e-121
Identities = 200/289 (69%), Positives = 239/289 (82%), Gaps = 2/289 (0%)
Query: 23 NQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMA 82
NQFVQP+W+I LW+ AY V+V +V+GN++V+WIILAHKRMRTVTNYFLVNLAF++ASMA
Sbjct: 76 NQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMA 135
Query: 83 AFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRL 142
AFNT+VNF YA+H+EWY+G YC+F NFFPI AVFASIYSMTA+A DRYMAII PL+PRL
Sbjct: 136 AFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRL 195
Query: 143 SATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTV 202
SATATK+VI IW+LA LLAFPQ YS T+ MP R +C ++WPE P + + YHI V +
Sbjct: 196 SATATKIVIGSIWILAFLLAFPQCLYSKTKVMPGRTLCFVQWPEGPKQHF--TYHIIVII 253
Query: 203 LIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWL 262
L+Y PLL++G YT+VGITLW EIPGD+ D+YHEQ+ AKRKVVKMMI+VV TFAICWL
Sbjct: 254 LVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVMTFAICWL 313
Query: 263 PFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDR 311
P+HI+F+L I L K+IQQVYLA WLAMSSTMYNPIIYCCLN R
Sbjct: 314 PYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKR 362
>gi|157426873 tachykinin receptor 2 [Homo sapiens]
Length = 398
Score = 358 bits (918), Expect = 4e-99
Identities = 168/305 (55%), Positives = 214/305 (70%), Gaps = 1/305 (0%)
Query: 8 DSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVT 67
++++S +NT+ F P+WQ+ LWA AY +V+ +V GN +V+WIILAH+RMRTVT
Sbjct: 9 EANISSGPESNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVT 68
Query: 68 NYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVA 127
NYF+VNLA A+ MAAFN NF YA HN WY+G +C F N FPI A+F SIYSMTA+A
Sbjct: 69 NYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIA 128
Query: 128 FDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEH 187
DRYMAI+HP QPRLSA +TK VI IW++AL LA PQ +YST C++ WPE
Sbjct: 129 ADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATKCVVAWPED 188
Query: 188 PNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYH-EQVSAKRKV 246
+YH+ V LIYFLPL V+ AY+V+G+TLW +PG + + + A +K
Sbjct: 189 SGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQAMKKF 248
Query: 247 VKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYC 306
VK M++VV TFAICWLP+H++F+L D+Y KFIQQVYLA+ WLAMSSTMYNPIIYC
Sbjct: 249 VKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYC 308
Query: 307 CLNDR 311
CLN R
Sbjct: 309 CLNHR 313
>gi|223633971 G protein-coupled receptor 83 [Homo sapiens]
Length = 423
Score = 179 bits (453), Expect = 4e-45
Identities = 100/286 (34%), Positives = 153/286 (53%), Gaps = 17/286 (5%)
Query: 34 LWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYA 93
L AY+ I+V S+ GNV+V +I ++RM + T+ F+VNLA A+ + NT
Sbjct: 73 LLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPFTLVRF 132
Query: 94 VHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICV 153
V++ W +G C F ++ S ++TA+A DR+ I+HPL+PR+S T + I V
Sbjct: 133 VNSTWIFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISITKGVIYIAV 192
Query: 154 IWVLALLLAFPQGYYSTTETMP-----SRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLP 208
IW +A + P T R +C+ ++PE P ++ K + +L+Y LP
Sbjct: 193 IWTMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPE-PADLFWKYLDLATFILLYILP 251
Query: 209 LLVIGYAYTVVGITLWASEIPGD-SSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIF 267
LL+I AY V LW + GD ++++Y K+K +KM+++VV FA+CW P + +
Sbjct: 252 LLIISVAYARVAKKLWLCNMIGDVTTEQYFALRRKKKKTIKMLMLVVVLFALCWFPLNCY 311
Query: 268 FLLPYINPDLYLKKFIQ---QVYLAIMWLAMSSTMYNPIIYCCLND 310
L L K I+ +Y A W AMSST YNP IYC LN+
Sbjct: 312 VL-------LLSSKVIRTNNALYFAFHWFAMSSTCYNPFIYCWLNE 350
>gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]
Length = 381
Score = 158 bits (400), Expect = 5e-39
Identities = 92/284 (32%), Positives = 150/284 (52%), Gaps = 9/284 (3%)
Query: 31 QIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNF 90
Q+VL AY I++ V+GN +V+ +++ K MRTVTN+F+ NLA A+ +
Sbjct: 50 QVVL-ILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTL 108
Query: 91 TYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVV 150
TY + EW G C + AV S ++T +A DR+ I++ L+ ++S + ++
Sbjct: 109 TYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLI 168
Query: 151 ICVIWVLALLLAFPQGY---YSTTETMP--SRVVCMIEWPEHPNKIYEKVYHICVTVLIY 205
I + W ++ LLA P YS E +P V C +WP IY VY + +++Y
Sbjct: 169 IGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILY 228
Query: 206 FLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFH 265
LPL +I ++YT + L PG ++D YH++ ++K KM++ VV FA+ WLP H
Sbjct: 229 VLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQR---RQKTTKMLVCVVVVFAVSWLPLH 285
Query: 266 IFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLN 309
F L I+ + K + ++ +AM ST NP++Y +N
Sbjct: 286 AFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMN 329
>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
Length = 370
Score = 150 bits (380), Expect = 1e-36
Identities = 89/276 (32%), Positives = 143/276 (51%), Gaps = 6/276 (2%)
Query: 39 YTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNE- 97
Y+V+VV +VGN +++ +I +R+ VTN+ + NLA ++ M + YA
Sbjct: 67 YSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFEPRG 126
Query: 98 WYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVL 157
W +G C F V+ S++++T +A DRY+ ++HPL+ R+S + + IW L
Sbjct: 127 WVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAVLAIWAL 186
Query: 158 ALLLAFPQGYYS-TTETMPSRV-VCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYA 215
+ +LA P ++ E P V +C W + ++Y + ++ Y LPLLVI +
Sbjct: 187 SAVLALPAAVHTYHVELKPHDVRLCEEFWGSQERQ--RQLYAWGLLLVTYLLPLLVILLS 244
Query: 216 YTVVGITLWASEIPGDSSDRYHEQVSA-KRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN 274
Y V + L +PG + + A +R+ +++VVV FA+CWLP H+F LL ++
Sbjct: 245 YVRVSVKLRNRVVPGCVTQSQADWDRARRRRTFCLLVVVVVVFAVCWLPLHVFNLLRDLD 304
Query: 275 PDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLND 310
P V L WLAMSS YNP IY L+D
Sbjct: 305 PHAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHD 340
>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
Length = 431
Score = 141 bits (355), Expect = 8e-34
Identities = 77/287 (26%), Positives = 145/287 (50%), Gaps = 20/287 (6%)
Query: 41 VIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYY 100
+I ++ GN +V +++ K MRTVTN F+ +LA ++ + F V + + W
Sbjct: 54 LIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLG 113
Query: 101 GLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATK--VVICVIWVLA 158
G F CK F AV I +MT +A +R+ ++HP + + T + ++ V+W++A
Sbjct: 114 GAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVA 173
Query: 159 LLLAFPQGYYSTTETM------PSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVI 212
+++ P + E + C+ EW + +++K+Y + V+++ LPL+V+
Sbjct: 174 VIVGSPMWHVQQLEIKYDFLYEKEHICCLEEW---TSPVHQKIYTTFILVILFLLPLMVM 230
Query: 213 GYAYTVVGITLWASEIPGDSS-------DRYHEQVSAKRKVVKMMIVVVCTFAICWLPFH 265
Y+ +G LW + GD S + K++ V MM+ VV FA+CW PFH
Sbjct: 231 LILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFH 290
Query: 266 -IFFLLPYINPDL-YLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLND 310
+ ++ Y N + Y I+ ++ + + S+++ NPI+Y +N+
Sbjct: 291 VVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNE 337
>gi|222080109 orexin receptor 2 [Homo sapiens]
Length = 444
Score = 138 bits (348), Expect = 5e-33
Identities = 91/347 (26%), Positives = 157/347 (45%), Gaps = 51/347 (14%)
Query: 13 PNISTNTSEPNQFVQPAWQIVL------WA--AAYTVIVVTSVVGNVVVMWIILAHKRMR 64
P ++ + +F++ W+ L W A Y ++ V +++GNV+V + + MR
Sbjct: 27 PFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMR 86
Query: 65 TVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMT 124
TVTNYF+VNL+ A+ + + W++G CK + +V S+ +++
Sbjct: 87 TVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLS 146
Query: 125 AVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETM--------PS 176
+A DR+ AI HPL + +A + I +IW+++ ++ PQ T+
Sbjct: 147 CIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTL 206
Query: 177 RVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRY 236
VC W +IY K+YHIC ++ Y PL ++ AY + LW +IPG SS
Sbjct: 207 FTVCDERW---GGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQ 263
Query: 237 H-----------------------------EQVSAKRKVVKMMIVVVCTFAICWLPFHIF 267
+Q+ A+RK +M+++V+ FAIC+LP I
Sbjct: 264 RKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISIL 323
Query: 268 FLLPYINPDLYLKKFIQQVYLAIM---WLAMSSTMYNPIIYCCLNDR 311
+L + + + VY WL +++ NPIIY L+ +
Sbjct: 324 NVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGK 370
>gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]
Length = 420
Score = 138 bits (348), Expect = 5e-33
Identities = 86/313 (27%), Positives = 156/313 (49%), Gaps = 25/313 (7%)
Query: 18 NTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFA 77
N + N ++ ++ +Y +I ++GN VV +I++ +K M TVTN F++NLA +
Sbjct: 31 NITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAIS 90
Query: 78 EASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHP 137
+ + F + + W +G CK +V AS++++ A+A DR+ +++P
Sbjct: 91 DLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYP 150
Query: 138 LQPRLSATATKVVICVIWVLALLLAFP---------QGYY-----STTETMPSRVVCMIE 183
+P+L+ V+I +IWVLA+ + P + YY S +T P C +
Sbjct: 151 FKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPV-YWCRED 209
Query: 184 WPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIP---GDSSDRYHEQV 240
W PN+ K+Y + IY PL +I Y +GI+L+ + +P + +++H
Sbjct: 210 W---PNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVS 266
Query: 241 SAKRKVVKMMIVVVCTFAICWLPFHIFFLL---PYINPDLYLKKFIQQVYLAIMWLAMSS 297
K+K++KM+++V F + WLP +L ++P+ L+ +Y WLA +
Sbjct: 267 RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPN-ELQIINIYIYPFAHWLAFGN 325
Query: 298 TMYNPIIYCCLND 310
+ NPIIY N+
Sbjct: 326 SSVNPIIYGFFNE 338
>gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]
Length = 522
Score = 138 bits (348), Expect = 5e-33
Identities = 86/313 (27%), Positives = 156/313 (49%), Gaps = 25/313 (7%)
Query: 18 NTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFA 77
N + N ++ ++ +Y +I ++GN VV +I++ +K M TVTN F++NLA +
Sbjct: 133 NITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAIS 192
Query: 78 EASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHP 137
+ + F + + W +G CK +V AS++++ A+A DR+ +++P
Sbjct: 193 DLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYP 252
Query: 138 LQPRLSATATKVVICVIWVLALLLAFP---------QGYY-----STTETMPSRVVCMIE 183
+P+L+ V+I +IWVLA+ + P + YY S +T P C +
Sbjct: 253 FKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPV-YWCRED 311
Query: 184 WPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIP---GDSSDRYHEQV 240
W PN+ K+Y + IY PL +I Y +GI+L+ + +P + +++H
Sbjct: 312 W---PNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVS 368
Query: 241 SAKRKVVKMMIVVVCTFAICWLPFHIFFLL---PYINPDLYLKKFIQQVYLAIMWLAMSS 297
K+K++KM+++V F + WLP +L ++P+ L+ +Y WLA +
Sbjct: 369 RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPN-ELQIINIYIYPFAHWLAFGN 427
Query: 298 TMYNPIIYCCLND 310
+ NPIIY N+
Sbjct: 428 SSVNPIIYGFFNE 440
>gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]
Length = 423
Score = 138 bits (348), Expect = 5e-33
Identities = 86/313 (27%), Positives = 156/313 (49%), Gaps = 25/313 (7%)
Query: 18 NTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFA 77
N + N ++ ++ +Y +I ++GN VV +I++ +K M TVTN F++NLA +
Sbjct: 34 NITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAIS 93
Query: 78 EASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHP 137
+ + F + + W +G CK +V AS++++ A+A DR+ +++P
Sbjct: 94 DLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYP 153
Query: 138 LQPRLSATATKVVICVIWVLALLLAFP---------QGYY-----STTETMPSRVVCMIE 183
+P+L+ V+I +IWVLA+ + P + YY S +T P C +
Sbjct: 154 FKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPV-YWCRED 212
Query: 184 WPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIP---GDSSDRYHEQV 240
W PN+ K+Y + IY PL +I Y +GI+L+ + +P + +++H
Sbjct: 213 W---PNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVS 269
Query: 241 SAKRKVVKMMIVVVCTFAICWLPFHIFFLL---PYINPDLYLKKFIQQVYLAIMWLAMSS 297
K+K++KM+++V F + WLP +L ++P+ L+ +Y WLA +
Sbjct: 270 RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPN-ELQIINIYIYPFAHWLAFGN 328
Query: 298 TMYNPIIYCCLND 310
+ NPIIY N+
Sbjct: 329 SSVNPIIYGFFNE 341
>gi|21426829 prokineticin receptor 2 [Homo sapiens]
Length = 384
Score = 136 bits (342), Expect = 3e-32
Identities = 70/285 (24%), Positives = 151/285 (52%), Gaps = 10/285 (3%)
Query: 29 AWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVV 88
A +IV+ A +++V + GN V + + +K++R +TN + NLA ++ +A
Sbjct: 51 AAKIVIGIALAGIMLVCGI-GNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPF 109
Query: 89 NFTYAVHNE--WYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA 146
Y V + W +G C N+ +++ S ++ A+A DRY+AI+HPL+PR++
Sbjct: 110 EMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQT 169
Query: 147 TKVVICVIWVLALLLAFPQGYYSTTETM-----PSRVVCMIEWPEHPNKIYEKVYHICVT 201
+I ++W++++L+A P Y++T + ++ C WP ++Y K Y + +
Sbjct: 170 ASFLIALVWMVSILIAIPSAYFATETVLFIVKSQEKIFCGQIWPV-DQQLYYKSYFLFIF 228
Query: 202 VLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICW 261
+ + P++ + Y + LW +PG +++ +++ +RK V +++ ++ + +CW
Sbjct: 229 GVEFVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCW 288
Query: 262 LPFHIFFLLPYINPDLYLK-KFIQQVYLAIMWLAMSSTMYNPIIY 305
PF+ F ++ P +++K K + + +AMS++M N + +
Sbjct: 289 APFYGFTIVRDFFPTVFVKEKHYLTAFYVVECIAMSNSMINTVCF 333
>gi|20373179 G protein-coupled receptor 73 [Homo sapiens]
Length = 393
Score = 135 bits (341), Expect = 4e-32
Identities = 72/286 (25%), Positives = 152/286 (53%), Gaps = 12/286 (4%)
Query: 29 AWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVV 88
A +IV+ A +++V + GN + + ++ +K++R +TN + NLA ++ +A
Sbjct: 60 AAKIVIGMALVGIMLVCGI-GNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPF 118
Query: 89 NFTYAVHNE--WYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA 146
Y V + W +G C N+ +++ S ++ A+A DRY+AI+HPL+PR+
Sbjct: 119 EMDYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQT 178
Query: 147 TKVVICVIWVLALLLAFPQGYYSTTETM------PSRVVCMIEWPEHPNKIYEKVYHICV 200
+I ++W +++L+A P Y+ TTET+ ++ C WP ++Y K Y + +
Sbjct: 179 ATGLIALVWTVSILIAIPSAYF-TTETVLVIVKSQEKIFCGQIWPV-DQQLYYKSYFLFI 236
Query: 201 TVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAIC 260
+ + P++ + Y + LW +PG +++ +++ +RK V +++ ++ + +C
Sbjct: 237 FGIEFVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLC 296
Query: 261 WLPFHIFFLLPYINPDLYLK-KFIQQVYLAIMWLAMSSTMYNPIIY 305
W PF+ F ++ P +++K K + + +AMS++M N + +
Sbjct: 297 WAPFYGFTIVRDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCF 342
>gi|4502455 bombesin-like receptor 3 [Homo sapiens]
Length = 399
Score = 133 bits (335), Expect = 2e-31
Identities = 71/276 (25%), Positives = 146/276 (52%), Gaps = 14/276 (5%)
Query: 39 YTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEW 98
Y VI+ ++GN +++ + K M+TV N F+ +LAF + + V+ T+ + W
Sbjct: 54 YAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGW 113
Query: 99 YYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPL--QPRLSATATKVVICVIWV 156
+G CK +F + +V S++++T ++ DRY A++ PL QP + T V +W+
Sbjct: 114 LFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWI 173
Query: 157 LALLLAFPQGYYSTTETM--PSRVVCMIEWPEHP--NKIYEKVYHICVTVLIYFLPLLVI 212
++++ A P+ +S T P++ + +P K+ ++++ + ++ Y +PL +I
Sbjct: 174 VSMIFALPEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSII 233
Query: 213 GYAYTVVGITLWAS--EIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLL 270
Y+++ TL+ S IP + +Q+ +++++ + ++V+V FA+CWLP H+ +L
Sbjct: 234 SVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLY 293
Query: 271 PYINPDLYL----KKFIQQVYLAIMWLAMSSTMYNP 302
Y+ FI ++ + LA S++ NP
Sbjct: 294 HSFTSQTYVDPSAMHFIFTIFSRV--LAFSNSCVNP 327
>gi|222080095 orexin receptor 1 [Homo sapiens]
Length = 425
Score = 130 bits (328), Expect = 1e-30
Identities = 87/327 (26%), Positives = 146/327 (44%), Gaps = 48/327 (14%)
Query: 27 QPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNT 86
Q W ++ AAY + V ++VGN +V + + MRTVTNYF+VNL+ A+ + A
Sbjct: 44 QYEWVLI---AAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICL 100
Query: 87 VVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA 146
+ + W +G CK + +V ++ +++ +A DR+ AI HPL + +A
Sbjct: 101 PASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARR 160
Query: 147 TKVVICVIWVLALLLAFPQ-GYYSTTETMPSRV-------VCMIEWPEHPNKIYEKVYHI 198
+ I IW ++L + PQ + +P VC W + +Y K+YH
Sbjct: 161 ARGSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWAD---DLYPKIYHS 217
Query: 199 CVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYH--------------------- 237
C ++ Y PL ++ AY + LW +IPG +S
Sbjct: 218 CFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQ 277
Query: 238 ----------EQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVY 287
+Q+ A+RK KM++VV+ FA+C+LP + +L + + VY
Sbjct: 278 PRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVY 337
Query: 288 LAIM---WLAMSSTMYNPIIYCCLNDR 311
WL +++ NPIIY L+ +
Sbjct: 338 ACFTFSHWLVYANSAANPIIYNFLSGK 364
>gi|63477962 opioid receptor, delta 1 [Homo sapiens]
Length = 372
Score = 130 bits (326), Expect = 2e-30
Identities = 81/278 (29%), Positives = 149/278 (53%), Gaps = 12/278 (4%)
Query: 37 AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96
A Y+ + ++GNV+VM+ I+ + +M+T TN ++ NLA A+A + + Y +
Sbjct: 54 ALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMET 113
Query: 97 EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQP---RLSATATKVVICV 153
W +G CK +F SI+++T ++ DRY+A+ HP++ R A A + IC
Sbjct: 114 -WPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINIC- 171
Query: 154 IWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIG 213
IWVLA + P + T VVCM+++P P+ ++ V ICV + + +P+L+I
Sbjct: 172 IWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPS-PSWYWDTVTKICVFLFAFVVPILIIT 230
Query: 214 YAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLL-PY 272
Y ++ + L + + S E+ + R++ +M++VVV F +CW P HIF ++
Sbjct: 231 VCYGLMLLRLRSVRLLSGSK----EKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTL 286
Query: 273 INPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLND 310
++ D + ++L I L +++ NP++Y L++
Sbjct: 287 VDIDRRDPLVVAALHLCIA-LGYANSSLNPVLYAFLDE 323
>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
Length = 380
Score = 130 bits (326), Expect = 2e-30
Identities = 76/289 (26%), Positives = 148/289 (51%), Gaps = 11/289 (3%)
Query: 26 VQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFN 85
+ PA +++ A Y+V+ V +VGN +VM++I+ + +M+T TN ++ NLA A+A +
Sbjct: 54 ISPAIPVII-TAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTM 112
Query: 86 TVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSAT 145
+ Y + N W +G CK +F SI+++T ++ DRY+A+ HP++ T
Sbjct: 113 PFQSTVYLM-NSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRT 171
Query: 146 --ATKVVICVIWVLALLLAFPQGYYSTTETMP--SRVVCMIEWPEHPNKIYEKVYHICVT 201
K++ IW+L+ + T+ + C +++P+ ++ ICV
Sbjct: 172 PLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVF 231
Query: 202 VLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICW 261
+ + +P+L+I YT++ + L + + S E+ R++ ++++VVV F +CW
Sbjct: 232 IFAFVIPVLIIIVCYTLMILRLKSVRLLSGS----REKDRNLRRITRLVLVVVAVFVVCW 287
Query: 262 LPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLND 310
P HIF L+ + + + Y I L +++ NPI+Y L++
Sbjct: 288 TPIHIFILVEALGSTSHSTAALSSYYFCIA-LGYTNSSLNPILYAFLDE 335
>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
Length = 384
Score = 127 bits (318), Expect = 2e-29
Identities = 80/313 (25%), Positives = 159/313 (50%), Gaps = 19/313 (6%)
Query: 5 LPVDSDLSPNISTNTSE---PNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHK 61
L VD + NIS+++++ + + P V+ A Y VI++ ++GN+ ++ I K
Sbjct: 11 LEVDHFMHCNISSHSADLPVNDDWSHPGILYVI-PAVYGVIILIGLIGNITLIKIFCTVK 69
Query: 62 RMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIY 121
MR V N F+ +LA + + V+ + + + W +G CK F + +V S++
Sbjct: 70 SMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVF 129
Query: 122 SMTAVAFDRYMAIIHPLQPRLSATATKVVI--CVIWVLALLLAFPQGYYST-----TETM 174
++TA++ DRY AI+ P+ + S K+ + IW++++LLA P+ +S E+
Sbjct: 130 TLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEEST 189
Query: 175 PSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWAS--EIPGDS 232
+ +P H N+++ K++ + ++ Y +PL +I Y + L S +P +
Sbjct: 190 NQTFISCAPYP-HSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQSAYNLPVEG 248
Query: 233 SDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFL---LPYINPDLYLKKFIQQVYLA 289
+ +Q+ +++++ K ++V V FA CWLP H+ +L Y D + F+ +
Sbjct: 249 NIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICAR 308
Query: 290 IMWLAMSSTMYNP 302
+ LA +++ NP
Sbjct: 309 L--LAFTNSCVNP 319
>gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]
Length = 384
Score = 126 bits (316), Expect = 3e-29
Identities = 87/292 (29%), Positives = 134/292 (45%), Gaps = 13/292 (4%)
Query: 28 PAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTV 87
P I A AY +++ V GN+ ++ IIL K MR VTN +VNL+F++ +A
Sbjct: 36 PLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLP 95
Query: 88 VNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATAT 147
F Y + + W +G CK + F ++ SI+S+ +A +R+ II+P R +
Sbjct: 96 FTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHA 155
Query: 148 KVVICVIWVLALLLAFPQGYYS----------TTETMPSRVVCMIEWPEHPNKIYEKVYH 197
V I VIWVLA+ + P Y T + + VC ++P +++ Y
Sbjct: 156 YVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRL---SYT 212
Query: 198 ICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTF 257
+ VL YF PL I Y + I L D + S +++ M++ +V F
Sbjct: 213 TLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAF 272
Query: 258 AICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLN 309
A+CWLP IF + N + ++L AM ST NPI Y LN
Sbjct: 273 AVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLN 324
>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
Length = 493
Score = 125 bits (314), Expect = 5e-29
Identities = 69/281 (24%), Positives = 141/281 (50%), Gaps = 19/281 (6%)
Query: 37 AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96
A Y+++ V + GN +VM++I+ + +M+T TN ++ NLA A+A + + Y +
Sbjct: 168 ALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLM-G 226
Query: 97 EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA--TKVVICVI 154
W +G CK +F SI+++ ++ DRY+A+ HP++ T K++
Sbjct: 227 TWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCN 286
Query: 155 WVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY 214
W+L+ + P + +TT+ + C + + HP +E + ICV + + +P+L+I
Sbjct: 287 WILSSAIGLPVMFMATTKYRQGSIDCTLTF-SHPTWYWENLLKICVFIFAFIMPVLIITV 345
Query: 215 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN 274
Y ++ + L + + S ++ R++ +M++VVV F +CW P HI+ ++
Sbjct: 346 CYGLMILRLKSVRMLSGSKEKDRN----LRRITRMVLVVVAVFIVCWTPIHIYVIIK--- 398
Query: 275 PDLYLKKFIQQVYLAIMW-----LAMSSTMYNPIIYCCLND 310
L + + + W L +++ NP++Y L++
Sbjct: 399 ---ALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDE 436
>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
Length = 400
Score = 125 bits (314), Expect = 5e-29
Identities = 69/281 (24%), Positives = 141/281 (50%), Gaps = 19/281 (6%)
Query: 37 AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96
A Y+++ V + GN +VM++I+ + +M+T TN ++ NLA A+A + + Y +
Sbjct: 75 ALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLM-G 133
Query: 97 EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA--TKVVICVI 154
W +G CK +F SI+++ ++ DRY+A+ HP++ T K++
Sbjct: 134 TWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCN 193
Query: 155 WVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY 214
W+L+ + P + +TT+ + C + + HP +E + ICV + + +P+L+I
Sbjct: 194 WILSSAIGLPVMFMATTKYRQGSIDCTLTF-SHPTWYWENLLKICVFIFAFIMPVLIITV 252
Query: 215 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN 274
Y ++ + L + + S ++ R++ +M++VVV F +CW P HI+ ++
Sbjct: 253 CYGLMILRLKSVRMLSGSKEKDRN----LRRITRMVLVVVAVFIVCWTPIHIYVIIK--- 305
Query: 275 PDLYLKKFIQQVYLAIMW-----LAMSSTMYNPIIYCCLND 310
L + + + W L +++ NP++Y L++
Sbjct: 306 ---ALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDE 343
>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
Length = 420
Score = 125 bits (314), Expect = 5e-29
Identities = 69/281 (24%), Positives = 141/281 (50%), Gaps = 19/281 (6%)
Query: 37 AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96
A Y+++ V + GN +VM++I+ + +M+T TN ++ NLA A+A + + Y +
Sbjct: 75 ALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLM-G 133
Query: 97 EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA--TKVVICVI 154
W +G CK +F SI+++ ++ DRY+A+ HP++ T K++
Sbjct: 134 TWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCN 193
Query: 155 WVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY 214
W+L+ + P + +TT+ + C + + HP +E + ICV + + +P+L+I
Sbjct: 194 WILSSAIGLPVMFMATTKYRQGSIDCTLTF-SHPTWYWENLLKICVFIFAFIMPVLIITV 252
Query: 215 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN 274
Y ++ + L + + S ++ R++ +M++VVV F +CW P HI+ ++
Sbjct: 253 CYGLMILRLKSVRMLSGSKEKDRN----LRRITRMVLVVVAVFIVCWTPIHIYVIIK--- 305
Query: 275 PDLYLKKFIQQVYLAIMW-----LAMSSTMYNPIIYCCLND 310
L + + + W L +++ NP++Y L++
Sbjct: 306 ---ALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDE 343
>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
Length = 397
Score = 125 bits (314), Expect = 5e-29
Identities = 69/281 (24%), Positives = 141/281 (50%), Gaps = 19/281 (6%)
Query: 37 AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96
A Y+++ V + GN +VM++I+ + +M+T TN ++ NLA A+A + + Y +
Sbjct: 75 ALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLM-G 133
Query: 97 EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA--TKVVICVI 154
W +G CK +F SI+++ ++ DRY+A+ HP++ T K++
Sbjct: 134 TWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCN 193
Query: 155 WVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY 214
W+L+ + P + +TT+ + C + + HP +E + ICV + + +P+L+I
Sbjct: 194 WILSSAIGLPVMFMATTKYRQGSIDCTLTF-SHPTWYWENLLKICVFIFAFIMPVLIITV 252
Query: 215 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN 274
Y ++ + L + + S ++ R++ +M++VVV F +CW P HI+ ++
Sbjct: 253 CYGLMILRLKSVRMLSGSKEKDRN----LRRITRMVLVVVAVFIVCWTPIHIYVIIK--- 305
Query: 275 PDLYLKKFIQQVYLAIMW-----LAMSSTMYNPIIYCCLND 310
L + + + W L +++ NP++Y L++
Sbjct: 306 ---ALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDE 343
>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
Length = 403
Score = 125 bits (314), Expect = 5e-29
Identities = 69/281 (24%), Positives = 141/281 (50%), Gaps = 19/281 (6%)
Query: 37 AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96
A Y+++ V + GN +VM++I+ + +M+T TN ++ NLA A+A + + Y +
Sbjct: 75 ALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLM-G 133
Query: 97 EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA--TKVVICVI 154
W +G CK +F SI+++ ++ DRY+A+ HP++ T K++
Sbjct: 134 TWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCN 193
Query: 155 WVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY 214
W+L+ + P + +TT+ + C + + HP +E + ICV + + +P+L+I
Sbjct: 194 WILSSAIGLPVMFMATTKYRQGSIDCTLTF-SHPTWYWENLLKICVFIFAFIMPVLIITV 252
Query: 215 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN 274
Y ++ + L + + S ++ R++ +M++VVV F +CW P HI+ ++
Sbjct: 253 CYGLMILRLKSVRMLSGSKEKDRN----LRRITRMVLVVVAVFIVCWTPIHIYVIIK--- 305
Query: 275 PDLYLKKFIQQVYLAIMW-----LAMSSTMYNPIIYCCLND 310
L + + + W L +++ NP++Y L++
Sbjct: 306 ---ALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDE 343
>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
Length = 406
Score = 125 bits (314), Expect = 5e-29
Identities = 69/281 (24%), Positives = 141/281 (50%), Gaps = 19/281 (6%)
Query: 37 AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96
A Y+++ V + GN +VM++I+ + +M+T TN ++ NLA A+A + + Y +
Sbjct: 75 ALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLM-G 133
Query: 97 EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA--TKVVICVI 154
W +G CK +F SI+++ ++ DRY+A+ HP++ T K++
Sbjct: 134 TWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCN 193
Query: 155 WVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY 214
W+L+ + P + +TT+ + C + + HP +E + ICV + + +P+L+I
Sbjct: 194 WILSSAIGLPVMFMATTKYRQGSIDCTLTF-SHPTWYWENLLKICVFIFAFIMPVLIITV 252
Query: 215 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN 274
Y ++ + L + + S ++ R++ +M++VVV F +CW P HI+ ++
Sbjct: 253 CYGLMILRLKSVRMLSGSKEKDRN----LRRITRMVLVVVAVFIVCWTPIHIYVIIK--- 305
Query: 275 PDLYLKKFIQQVYLAIMW-----LAMSSTMYNPIIYCCLND 310
L + + + W L +++ NP++Y L++
Sbjct: 306 ---ALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDE 343
>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
Length = 392
Score = 125 bits (314), Expect = 5e-29
Identities = 69/281 (24%), Positives = 141/281 (50%), Gaps = 19/281 (6%)
Query: 37 AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96
A Y+++ V + GN +VM++I+ + +M+T TN ++ NLA A+A + + Y +
Sbjct: 75 ALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLM-G 133
Query: 97 EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA--TKVVICVI 154
W +G CK +F SI+++ ++ DRY+A+ HP++ T K++
Sbjct: 134 TWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCN 193
Query: 155 WVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY 214
W+L+ + P + +TT+ + C + + HP +E + ICV + + +P+L+I
Sbjct: 194 WILSSAIGLPVMFMATTKYRQGSIDCTLTF-SHPTWYWENLLKICVFIFAFIMPVLIITV 252
Query: 215 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN 274
Y ++ + L + + S ++ R++ +M++VVV F +CW P HI+ ++
Sbjct: 253 CYGLMILRLKSVRMLSGSKEKDRN----LRRITRMVLVVVAVFIVCWTPIHIYVIIK--- 305
Query: 275 PDLYLKKFIQQVYLAIMW-----LAMSSTMYNPIIYCCLND 310
L + + + W L +++ NP++Y L++
Sbjct: 306 ---ALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDE 343
>gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]
Length = 389
Score = 125 bits (314), Expect = 5e-29
Identities = 69/281 (24%), Positives = 141/281 (50%), Gaps = 19/281 (6%)
Query: 37 AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96
A Y+++ V + GN +VM++I+ + +M+T TN ++ NLA A+A + + Y +
Sbjct: 75 ALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLM-G 133
Query: 97 EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA--TKVVICVI 154
W +G CK +F SI+++ ++ DRY+A+ HP++ T K++
Sbjct: 134 TWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCN 193
Query: 155 WVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY 214
W+L+ + P + +TT+ + C + + HP +E + ICV + + +P+L+I
Sbjct: 194 WILSSAIGLPVMFMATTKYRQGSIDCTLTF-SHPTWYWENLLKICVFIFAFIMPVLIITV 252
Query: 215 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN 274
Y ++ + L + + S ++ R++ +M++VVV F +CW P HI+ ++
Sbjct: 253 CYGLMILRLKSVRMLSGSKEKDRN----LRRITRMVLVVVAVFIVCWTPIHIYVIIK--- 305
Query: 275 PDLYLKKFIQQVYLAIMW-----LAMSSTMYNPIIYCCLND 310
L + + + W L +++ NP++Y L++
Sbjct: 306 ---ALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDE 343
>gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]
Length = 418
Score = 125 bits (314), Expect = 5e-29
Identities = 69/281 (24%), Positives = 141/281 (50%), Gaps = 19/281 (6%)
Query: 37 AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96
A Y+++ V + GN +VM++I+ + +M+T TN ++ NLA A+A + + Y +
Sbjct: 75 ALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLM-G 133
Query: 97 EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA--TKVVICVI 154
W +G CK +F SI+++ ++ DRY+A+ HP++ T K++
Sbjct: 134 TWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCN 193
Query: 155 WVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY 214
W+L+ + P + +TT+ + C + + HP +E + ICV + + +P+L+I
Sbjct: 194 WILSSAIGLPVMFMATTKYRQGSIDCTLTF-SHPTWYWENLLKICVFIFAFIMPVLIITV 252
Query: 215 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN 274
Y ++ + L + + S ++ R++ +M++VVV F +CW P HI+ ++
Sbjct: 253 CYGLMILRLKSVRMLSGSKEKDRN----LRRITRMVLVVVAVFIVCWTPIHIYVIIK--- 305
Query: 275 PDLYLKKFIQQVYLAIMW-----LAMSSTMYNPIIYCCLND 310
L + + + W L +++ NP++Y L++
Sbjct: 306 ---ALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDE 343
>gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]
Length = 446
Score = 125 bits (314), Expect = 5e-29
Identities = 69/281 (24%), Positives = 141/281 (50%), Gaps = 19/281 (6%)
Query: 37 AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96
A Y+++ V + GN +VM++I+ + +M+T TN ++ NLA A+A + + Y +
Sbjct: 75 ALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLM-G 133
Query: 97 EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATA--TKVVICVI 154
W +G CK +F SI+++ ++ DRY+A+ HP++ T K++
Sbjct: 134 TWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCN 193
Query: 155 WVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY 214
W+L+ + P + +TT+ + C + + HP +E + ICV + + +P+L+I
Sbjct: 194 WILSSAIGLPVMFMATTKYRQGSIDCTLTF-SHPTWYWENLLKICVFIFAFIMPVLIITV 252
Query: 215 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN 274
Y ++ + L + + S ++ R++ +M++VVV F +CW P HI+ ++
Sbjct: 253 CYGLMILRLKSVRMLSGSKEKDRN----LRRITRMVLVVVAVFIVCWTPIHIYVIIK--- 305
Query: 275 PDLYLKKFIQQVYLAIMW-----LAMSSTMYNPIIYCCLND 310
L + + + W L +++ NP++Y L++
Sbjct: 306 ---ALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDE 343
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.139 0.452
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,724,366
Number of Sequences: 37866
Number of extensions: 408992
Number of successful extensions: 2886
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 428
Number of HSP's successfully gapped in prelim test: 308
Number of HSP's that attempted gapping in prelim test: 1369
Number of HSP's gapped (non-prelim): 852
length of query: 311
length of database: 18,247,518
effective HSP length: 102
effective length of query: 209
effective length of database: 14,385,186
effective search space: 3006503874
effective search space used: 3006503874
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.