Search of human proteins with 7661548

Search of human proteins with 7661548

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7661548 methylmalonic aciduria (cobalamin deficiency) cblD
type, with homocystinuria precursor [Homo sapiens]
         (296 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7661548 methylmalonic aciduria (cobalamin deficiency) cblD ty...   610   e-175
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         29   4.3  
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         29   4.3  
gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]            28   7.4  
gi|39753961 IQ motif containing GTPase activating protein 3 [Hom...    28   7.4  
gi|40068483 SET domain containing 3 isoform b [Homo sapiens]           28   9.7  
gi|40068481 SET domain containing 3 isoform a [Homo sapiens]           28   9.7  

>gi|7661548 methylmalonic aciduria (cobalamin deficiency) cblD type,
           with homocystinuria precursor [Homo sapiens]
          Length = 296

 Score =  610 bits (1573), Expect = e-175
 Identities = 296/296 (100%), Positives = 296/296 (100%)

Query: 1   MANVLCNRARLVSYLPGFCSLVKRVVNPKAFSTAGSSGSDESHVAAAPPDICSRTVWPDE 60
           MANVLCNRARLVSYLPGFCSLVKRVVNPKAFSTAGSSGSDESHVAAAPPDICSRTVWPDE
Sbjct: 1   MANVLCNRARLVSYLPGFCSLVKRVVNPKAFSTAGSSGSDESHVAAAPPDICSRTVWPDE 60

Query: 61  TMGPFGPQDQRFQLPGNIGFDCHLNGTASQKKSLVHKTLPDVLAEPLSSERHEFVMAQYV 120
           TMGPFGPQDQRFQLPGNIGFDCHLNGTASQKKSLVHKTLPDVLAEPLSSERHEFVMAQYV
Sbjct: 61  TMGPFGPQDQRFQLPGNIGFDCHLNGTASQKKSLVHKTLPDVLAEPLSSERHEFVMAQYV 120

Query: 121 NEFQGNDAPVEQEINSAETYFESARVECAIQTCPELLRKDFESLFPEVANGKLMILTVTQ 180
           NEFQGNDAPVEQEINSAETYFESARVECAIQTCPELLRKDFESLFPEVANGKLMILTVTQ
Sbjct: 121 NEFQGNDAPVEQEINSAETYFESARVECAIQTCPELLRKDFESLFPEVANGKLMILTVTQ 180

Query: 181 KTKNDMTVWSEEVEIEREVLLEKFINGAKEICYALRAEGYWADFIDPSSGLAFFGPYTNN 240
           KTKNDMTVWSEEVEIEREVLLEKFINGAKEICYALRAEGYWADFIDPSSGLAFFGPYTNN
Sbjct: 181 KTKNDMTVWSEEVEIEREVLLEKFINGAKEICYALRAEGYWADFIDPSSGLAFFGPYTNN 240

Query: 241 TLFETDERYRHLGFSVDDLGCCKVIRHSLWGTHVVVGSIFTNATPDSHIMKKLSGN 296
           TLFETDERYRHLGFSVDDLGCCKVIRHSLWGTHVVVGSIFTNATPDSHIMKKLSGN
Sbjct: 241 TLFETDERYRHLGFSVDDLGCCKVIRHSLWGTHVVVGSIFTNATPDSHIMKKLSGN 296


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 26/109 (23%), Positives = 50/109 (45%), Gaps = 7/109 (6%)

Query: 110 ERHEFVMAQYVNEFQGNDAPVEQEI----NSAETYFESARVECAIQTCPELLRKDFESLF 165
           E+ +  + Q V E Q     +E+++    N  +  F     E +I    +   +D   + 
Sbjct: 735 EKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIH 794

Query: 166 PEVANGKLMILTVTQKTKNDMTVWSEEVEI---EREVLLEKFINGAKEI 211
             V+  + +I   + K+K+  +VW +E+EI   E E L ++ I   +EI
Sbjct: 795 TPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEI 843


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 26/109 (23%), Positives = 50/109 (45%), Gaps = 7/109 (6%)

Query: 110 ERHEFVMAQYVNEFQGNDAPVEQEI----NSAETYFESARVECAIQTCPELLRKDFESLF 165
           E+ +  + Q V E Q     +E+++    N  +  F     E +I    +   +D   + 
Sbjct: 735 EKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIH 794

Query: 166 PEVANGKLMILTVTQKTKNDMTVWSEEVEI---EREVLLEKFINGAKEI 211
             V+  + +I   + K+K+  +VW +E+EI   E E L ++ I   +EI
Sbjct: 795 TPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEI 843


>gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]
          Length = 1720

 Score = 28.5 bits (62), Expect = 7.4
 Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 8/66 (12%)

Query: 238 TNNTLFETDERYRHLGFS--VDDLGCCKVIRHS------LWGTHVVVGSIFTNATPDSHI 289
           T    F T E Y  L +    D +G  K++  S      LW    VV ++  N  P+ HI
Sbjct: 642 TTRGCFFTREHYMELVYRGLTDKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHI 701

Query: 290 MKKLSG 295
              LSG
Sbjct: 702 PLNLSG 707


>gi|39753961 IQ motif containing GTPase activating protein 3 [Homo
           sapiens]
          Length = 1631

 Score = 28.5 bits (62), Expect = 7.4
 Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 9/81 (11%)

Query: 153 CPELLRKDFESLFPEVANGKLMILTVTQKTKNDMTVWSEEVEIEREVLLEK-FINGAKEI 211
           CPE        ++P  ++   + L V Q+ + ++    EE+ +  E+L     IN A E 
Sbjct: 402 CPEA---QLPPVYPVASSMYQLELAVLQQQQGELG--QEELFVAVEMLSAVVLINRALE- 455

Query: 212 CYALRAEGYWADFIDPSSGLA 232
             A  A G+W+  ++P++GLA
Sbjct: 456 --ARDASGFWSSLVNPATGLA 474


>gi|40068483 SET domain containing 3 isoform b [Homo sapiens]
          Length = 296

 Score = 28.1 bits (61), Expect = 9.7
 Identities = 29/99 (29%), Positives = 38/99 (38%), Gaps = 9/99 (9%)

Query: 59  DETMGPFGPQDQRFQLPGNIGFDCHLNGTASQKKSLVH---KTLPDVLAEPLSSERHEFV 115
           +  +GP   QD+  Q  GNI    HL    +   S      +TLP     PL  E  E  
Sbjct: 136 NSVLGPLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEDE-- 193

Query: 116 MAQYVNEFQGNDAPVEQEINSAETYFESARVECAIQTCP 154
             +Y+   Q       Q  N+A  Y    +V   IQT P
Sbjct: 194 -VRYLQSTQAIHDVFSQYKNTARQYAYFYKV---IQTHP 228


>gi|40068481 SET domain containing 3 isoform a [Homo sapiens]
          Length = 594

 Score = 28.1 bits (61), Expect = 9.7
 Identities = 29/99 (29%), Positives = 38/99 (38%), Gaps = 9/99 (9%)

Query: 59  DETMGPFGPQDQRFQLPGNIGFDCHLNGTASQKKSLVH---KTLPDVLAEPLSSERHEFV 115
           +  +GP   QD+  Q  GNI    HL    +   S      +TLP     PL  E  E  
Sbjct: 136 NSVLGPLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEDE-- 193

Query: 116 MAQYVNEFQGNDAPVEQEINSAETYFESARVECAIQTCP 154
             +Y+   Q       Q  N+A  Y    +V   IQT P
Sbjct: 194 -VRYLQSTQAIHDVFSQYKNTARQYAYFYKV---IQTHP 228


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,854,278
Number of Sequences: 37866
Number of extensions: 533192
Number of successful extensions: 1137
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1136
Number of HSP's gapped (non-prelim): 7
length of query: 296
length of database: 18,247,518
effective HSP length: 102
effective length of query: 194
effective length of database: 14,385,186
effective search space: 2790726084
effective search space used: 2790726084
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.