Search of human proteins with 74271840

Search of human proteins with 74271840

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74271840 exostoses-like 2 [Homo sapiens]
         (330 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74271840 exostoses-like 2 [Homo sapiens]                           667   0.0  
gi|14149609 exostoses-like 2 [Homo sapiens]                           667   0.0  
gi|46370069 exostosin 2 isoform 2 [Homo sapiens]                      137   1e-32
gi|184172392 exostosin 2 isoform 1 [Homo sapiens]                     137   1e-32
gi|4503617 exostoses-like 3 [Homo sapiens]                            137   1e-32
gi|46370066 exostosin 1 [Homo sapiens]                                106   3e-23
gi|112382285 exostoses-like 1 [Homo sapiens]                           81   1e-15
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s...    31   1.7  
gi|119220605 ubiquitin specific protease 10 [Homo sapiens]             30   3.0  
gi|4507001 solute carrier family 22 member 2 [Homo sapiens]            28   8.6  

>gi|74271840 exostoses-like 2 [Homo sapiens]
          Length = 330

 Score =  667 bits (1720), Expect = 0.0
 Identities = 330/330 (100%), Positives = 330/330 (100%)

Query: 1   MRCCHICKLPGRVMGIRVLRLSLVVILVLLLVAGALTALLPSVKEDKMLMLRREIKSQGK 60
           MRCCHICKLPGRVMGIRVLRLSLVVILVLLLVAGALTALLPSVKEDKMLMLRREIKSQGK
Sbjct: 1   MRCCHICKLPGRVMGIRVLRLSLVVILVLLLVAGALTALLPSVKEDKMLMLRREIKSQGK 60

Query: 61  STMDSFTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIP 120
           STMDSFTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIP
Sbjct: 61  STMDSFTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIP 120

Query: 121 VIFKQQTANRMRNRLQVFPELETNAVLMVDDDTLISTPDLVFAFSVWQQFPDQIVGFVPR 180
           VIFKQQTANRMRNRLQVFPELETNAVLMVDDDTLISTPDLVFAFSVWQQFPDQIVGFVPR
Sbjct: 121 VIFKQQTANRMRNRLQVFPELETNAVLMVDDDTLISTPDLVFAFSVWQQFPDQIVGFVPR 180

Query: 181 KHVSTSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELFQRQPAAVHALIDDT 240
           KHVSTSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELFQRQPAAVHALIDDT
Sbjct: 181 KHVSTSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELFQRQPAAVHALIDDT 240

Query: 241 QNCDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKL 300
           QNCDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKL
Sbjct: 241 QNCDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKL 300

Query: 301 VNIYDSMPLRYSNIMISQFGFPYANYKRKI 330
           VNIYDSMPLRYSNIMISQFGFPYANYKRKI
Sbjct: 301 VNIYDSMPLRYSNIMISQFGFPYANYKRKI 330


>gi|14149609 exostoses-like 2 [Homo sapiens]
          Length = 330

 Score =  667 bits (1720), Expect = 0.0
 Identities = 330/330 (100%), Positives = 330/330 (100%)

Query: 1   MRCCHICKLPGRVMGIRVLRLSLVVILVLLLVAGALTALLPSVKEDKMLMLRREIKSQGK 60
           MRCCHICKLPGRVMGIRVLRLSLVVILVLLLVAGALTALLPSVKEDKMLMLRREIKSQGK
Sbjct: 1   MRCCHICKLPGRVMGIRVLRLSLVVILVLLLVAGALTALLPSVKEDKMLMLRREIKSQGK 60

Query: 61  STMDSFTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIP 120
           STMDSFTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIP
Sbjct: 61  STMDSFTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIP 120

Query: 121 VIFKQQTANRMRNRLQVFPELETNAVLMVDDDTLISTPDLVFAFSVWQQFPDQIVGFVPR 180
           VIFKQQTANRMRNRLQVFPELETNAVLMVDDDTLISTPDLVFAFSVWQQFPDQIVGFVPR
Sbjct: 121 VIFKQQTANRMRNRLQVFPELETNAVLMVDDDTLISTPDLVFAFSVWQQFPDQIVGFVPR 180

Query: 181 KHVSTSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELFQRQPAAVHALIDDT 240
           KHVSTSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELFQRQPAAVHALIDDT
Sbjct: 181 KHVSTSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELFQRQPAAVHALIDDT 240

Query: 241 QNCDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKL 300
           QNCDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKL
Sbjct: 241 QNCDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKL 300

Query: 301 VNIYDSMPLRYSNIMISQFGFPYANYKRKI 330
           VNIYDSMPLRYSNIMISQFGFPYANYKRKI
Sbjct: 301 VNIYDSMPLRYSNIMISQFGFPYANYKRKI 330


>gi|46370069 exostosin 2 isoform 2 [Homo sapiens]
          Length = 718

 Score =  137 bits (346), Expect = 1e-32
 Identities = 79/248 (31%), Positives = 137/248 (55%), Gaps = 16/248 (6%)

Query: 66  FTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAP-DELWNSLGPHPIPVIFK 124
           FT I+ TY+R + L +++     VP+L K++VVWNN  +  P D LW  +    +P+   
Sbjct: 456 FTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKI---RVPLKVV 512

Query: 125 QQTANRMRNRLQVFPELETNAVLMVDDDTLISTPD-LVFAFSVWQQFPDQIVGFVPRKHV 183
           +   N++ NR   + E+ET AVL +DDD ++ T D L F + VW++FPD++VG+  R H+
Sbjct: 513 RTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHL 572

Query: 184 STSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELF-QRQPAAVHALIDDTQN 242
                 +    ++ ++  +   ++ SMVL GA+F++  +  L+  + P  +   +D   N
Sbjct: 573 WD----HEMNKWKYESEWT---NEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMN 625

Query: 243 CDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKLVN 302
           C+DIAMNF++A   GK     +K       +    +   G+     H ++RS CINK  +
Sbjct: 626 CEDIAMNFLVANVTGKA---VIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFAS 682

Query: 303 IYDSMPLR 310
           ++ +MPL+
Sbjct: 683 VFGTMPLK 690


>gi|184172392 exostosin 2 isoform 1 [Homo sapiens]
          Length = 731

 Score =  137 bits (346), Expect = 1e-32
 Identities = 79/248 (31%), Positives = 137/248 (55%), Gaps = 16/248 (6%)

Query: 66  FTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAP-DELWNSLGPHPIPVIFK 124
           FT I+ TY+R + L +++     VP+L K++VVWNN  +  P D LW  +    +P+   
Sbjct: 469 FTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKI---RVPLKVV 525

Query: 125 QQTANRMRNRLQVFPELETNAVLMVDDDTLISTPD-LVFAFSVWQQFPDQIVGFVPRKHV 183
           +   N++ NR   + E+ET AVL +DDD ++ T D L F + VW++FPD++VG+  R H+
Sbjct: 526 RTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHL 585

Query: 184 STSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELF-QRQPAAVHALIDDTQN 242
                 +    ++ ++  +   ++ SMVL GA+F++  +  L+  + P  +   +D   N
Sbjct: 586 WD----HEMNKWKYESEWT---NEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMN 638

Query: 243 CDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKLVN 302
           C+DIAMNF++A   GK     +K       +    +   G+     H ++RS CINK  +
Sbjct: 639 CEDIAMNFLVANVTGKA---VIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFAS 695

Query: 303 IYDSMPLR 310
           ++ +MPL+
Sbjct: 696 VFGTMPLK 703


>gi|4503617 exostoses-like 3 [Homo sapiens]
          Length = 919

 Score =  137 bits (345), Expect = 1e-32
 Identities = 85/268 (31%), Positives = 137/268 (51%), Gaps = 24/268 (8%)

Query: 59  GKSTMDSFTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHP 118
           G    + FT++M TY R ++L+  L     +P L+KV+VVWN+    + D LW  +G   
Sbjct: 656 GNVPREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIG--- 712

Query: 119 IPVIFKQQTANRMRNRLQVFPELETNAVLMVDDDTLISTPDLVFAFSVWQQFPDQIVGFV 178
           +P++  +   N + NR   + E+ET A+L +DDD  +   +++F F VW++  D+IVGF 
Sbjct: 713 VPIMVVRTEKNSLNNRFLPWNEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFP 772

Query: 179 PRKH---VSTSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELFQR-QPAAVH 234
            R H   +   S +Y+          S    + SMVL GA+FF+  Y  L+    P A+ 
Sbjct: 773 GRYHAWDIPHQSWLYN----------SNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIR 822

Query: 235 ALIDDTQNCDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGY-SGMWHRAEHALQR 293
            ++D+  NC+DIAMNF+++ HI +       P+ + +       G    + H   H  +R
Sbjct: 823 DMVDEYINCEDIAMNFLVS-HITRK-----PPIKVTSRWTFRCPGCPQALSHDDSHFHER 876

Query: 294 SYCINKLVNIYDSMPLRYSNIMISQFGF 321
             CIN  V +Y  MPL Y+   +    F
Sbjct: 877 HKCINFFVKVYGYMPLLYTQFRVDSVLF 904


>gi|46370066 exostosin 1 [Homo sapiens]
          Length = 746

 Score =  106 bits (264), Expect = 3e-23
 Identities = 74/242 (30%), Positives = 120/242 (49%), Gaps = 18/242 (7%)

Query: 79  LLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIPVIFKQQTANRMRNRLQVF 138
           +LKLL          ++IV+WN          W +     +PV+  +  +  M +R   +
Sbjct: 497 VLKLLVAAAKSQYCAQIIVLWNCDKPLPAKHRWPATA---VPVVVIEGESKVMSSRFLPY 553

Query: 139 PELETNAVLMVDDDTLISTPDLVFAFSVWQQFPDQIVGFVPRKHVSTSSGIYSYGSFEMQ 198
             + T+AVL +D+DT++ST ++ FAF+VWQ FP++IVG+  R H       +   S E  
Sbjct: 554 DNIITDAVLSLDEDTVLSTTEVDFAFTVWQSFPERIVGYPARSH-------FWDNSKERW 606

Query: 199 APGSGNGDQYSMVLIGASFFNSKYLELFQRQ-PAAVHALIDDTQNCDDIAMNFIIAKHIG 257
              S   + YSMVL GA+ ++  Y  L+    PA++  ++D   NC+DI MNF+++  + 
Sbjct: 607 GYTSKWTNDYSMVLTGAAIYHKYYHYLYSHYLPASLKNMVDQLANCEDILMNFLVSA-VT 665

Query: 258 KTSGIFVKPVNMDNLEKETNSGY---SGMWHRAEHALQRSYCINKLVNIYDSMPLRYSNI 314
           K   I    V      KET  G    +  W   +H  QR  C+N   + +  MPL +S +
Sbjct: 666 KLPPI---KVTQKKQYKETMMGQTSRASRWADPDHFAQRQSCMNTFASWFGYMPLIHSQM 722

Query: 315 MI 316
            +
Sbjct: 723 RL 724


>gi|112382285 exostoses-like 1 [Homo sapiens]
          Length = 676

 Score = 80.9 bits (198), Expect = 1e-15
 Identities = 66/238 (27%), Positives = 114/238 (47%), Gaps = 17/238 (7%)

Query: 80  LKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIPVIFKQQTANRMRNRLQVFP 139
           LKL+       +  +++V+W+N  E+     W      P+ VI   +   ++ +R   + 
Sbjct: 433 LKLIQAVAGSQHCAQILVLWSN--ERPLPSRWPETAV-PLTVIDGHR---KVSDRFYPYS 486

Query: 140 ELETNAVLMVDDDTLISTPDLVFAFSVWQQFPDQIVGFVPRKHVSTSSGIYSYGSFEMQA 199
            + T+A+L +D  + +ST ++ FAF VWQ FP+++VGF+   H        ++G +   A
Sbjct: 487 TIRTDAILSLDARSSLSTSEVDFAFLVWQSFPERMVGFLTSSHFWDE----AHGGWGYTA 542

Query: 200 PGSGNGDQYSMVLIGASFFNSKYLELFQRQ-PAAVHALIDDTQNCDDIAMNFIIAKHIGK 258
             +   +++SMVL  A+F++  Y  LF    P A+  L D+   C D+ MNFI+A  + K
Sbjct: 543 ERT---NEFSMVLTTAAFYHRYYHTLFTHSLPKALRTLADEAPTCVDVLMNFIVAA-VTK 598

Query: 259 TSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKLVNIYDSMPLRYSNIMI 316
              I V P      E    +   G   R +       CIN++   +  MPL  S + +
Sbjct: 599 LPPIKV-PYGKQRQEAAPLAP-GGPGPRPKPPAPAPDCINQIAAAFGHMPLLSSRLRL 654


>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
           sapiens]
          Length = 376

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 16/47 (34%), Positives = 24/47 (51%)

Query: 180 RKHVSTSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELF 226
           RKH++T     + G  E   PGS    +  +VL+ A +F  K+ E F
Sbjct: 129 RKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPF 175


>gi|119220605 ubiquitin specific protease 10 [Homo sapiens]
          Length = 798

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 11/76 (14%)

Query: 152 DTLISTPDLVFAFSVWQQFPDQIVGFVPRKHVSTSSGIY---SYGSFEMQAPGSGNGDQY 208
           DTL  TP    + ++  Q P+ I+G    K   T  GI    SYGS + Q PGS      
Sbjct: 69  DTLPRTPSYSISSTLNPQAPEFILGCTASK--ITPDGITKEASYGSIDCQYPGS------ 120

Query: 209 SMVLIGASFFNSKYLE 224
           ++ L G+S   ++ LE
Sbjct: 121 ALALDGSSNVEAEVLE 136


>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
          Length = 555

 Score = 28.5 bits (62), Expect = 8.6
 Identities = 19/49 (38%), Positives = 24/49 (48%), Gaps = 7/49 (14%)

Query: 3   CCHICKLPGRVMGIRVLRLS-------LVVILVLLLVAGALTALLPSVK 44
           C  +C + G +    V RL+       L+V  VL LVAG L  LLP  K
Sbjct: 470 CSSMCDIGGIITPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPETK 518


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,013,071
Number of Sequences: 37866
Number of extensions: 499948
Number of successful extensions: 953
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 921
Number of HSP's gapped (non-prelim): 11
length of query: 330
length of database: 18,247,518
effective HSP length: 103
effective length of query: 227
effective length of database: 14,347,320
effective search space: 3256841640
effective search space used: 3256841640
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.