Search of human proteins with 74048434

Search of human proteins with 74048434

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74048434 leucine carboxyl methyltransferase 1 isoform a
[Homo sapiens]
         (334 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74048434 leucine carboxyl methyltransferase 1 isoform a [Homo...   682   0.0  
gi|74048545 leucine carboxyl methyltransferase 1 isoform b [Homo...   539   e-153
gi|25188199 leucine carboxyl methyltransferase 2 [Homo sapiens]       179   4e-45
gi|31982906 cingulin-like 1 [Homo sapiens]                             33   0.36 
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]        30   3.9  
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                    29   5.2  
gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5...    28   8.8  

>gi|74048434 leucine carboxyl methyltransferase 1 isoform a [Homo
           sapiens]
          Length = 334

 Score =  682 bits (1761), Expect = 0.0
 Identities = 334/334 (100%), Positives = 334/334 (100%)

Query: 1   MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE 60
           MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE
Sbjct: 1   MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE 60

Query: 61  RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE 120
           RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE
Sbjct: 61  RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE 120

Query: 121 VDFPMIVTRKLHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEE 180
           VDFPMIVTRKLHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEE
Sbjct: 121 VDFPMIVTRKLHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEE 180

Query: 181 KLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQI 240
           KLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQI
Sbjct: 181 KLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQI 240

Query: 241 MIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLE 300
           MIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLE
Sbjct: 241 MIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLE 300

Query: 301 FLDEMELLEQLMRHYCLCWATKGGNELGLKEITY 334
           FLDEMELLEQLMRHYCLCWATKGGNELGLKEITY
Sbjct: 301 FLDEMELLEQLMRHYCLCWATKGGNELGLKEITY 334


>gi|74048545 leucine carboxyl methyltransferase 1 isoform b [Homo
           sapiens]
          Length = 279

 Score =  539 bits (1389), Expect = e-153
 Identities = 277/334 (82%), Positives = 278/334 (83%), Gaps = 55/334 (16%)

Query: 1   MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE 60
           MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE
Sbjct: 1   MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE 60

Query: 61  RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE 120
           RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE
Sbjct: 61  RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE 120

Query: 121 VDFPMIVTRKLHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEE 180
           VDFPMIVTRK                LHS                               
Sbjct: 121 VDFPMIVTRK----------------LHS------------------------------- 133

Query: 181 KLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQI 240
                    +LPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQI
Sbjct: 134 --------IKLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQI 185

Query: 241 MIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLE 300
           MIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLE
Sbjct: 186 MIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLE 245

Query: 301 FLDEMELLEQLMRHYCLCWATKGGNELGLKEITY 334
           FLDEMELLEQLMRHYCLCWATKGGNELGLKEITY
Sbjct: 246 FLDEMELLEQLMRHYCLCWATKGGNELGLKEITY 279


>gi|25188199 leucine carboxyl methyltransferase 2 [Homo sapiens]
          Length = 686

 Score =  179 bits (453), Expect = 4e-45
 Identities = 111/305 (36%), Positives = 160/305 (52%), Gaps = 10/305 (3%)

Query: 26  VRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKERKAPEINRGYFARVHGVSQLIKAFL 85
           V+ T + ++L KR   + GY  DP+    V     R+AP I+RGY+ R   V   ++AFL
Sbjct: 13  VQNTNDSSALSKRSLAARGYVQDPFAALLVP-GAARRAPLIHRGYYVRARAVRHCVRAFL 71

Query: 86  RK-----TECHCQIVNLGAGMDTTFWRLKDEDLLP-SKYFEVDFPMIVTRKLHSIKCKPP 139
            +          QI++LGAG D+ ++RLK    L  +  +EVDFP +  RK   I   P 
Sbjct: 72  EQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLARAAVWEVDFPDVARRKAERIGETPE 131

Query: 140 LSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEEKLKKCNMNTQLPTLLIAEC 199
           L +  L    E          +S  Y ++G DLR L  +EE L    ++   PTLL+AE 
Sbjct: 132 LCA--LTGPFERGEPASALCFESADYCILGLDLRQLQRVEEALGAAGLDAASPTLLLAEA 189

Query: 200 VLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLRRRQCDLAGVETCK 259
           VL Y+ PE +A L+ WAA  F  A+F+ YEQ+   D FGQ M+++ R+    L G+E   
Sbjct: 190 VLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFMLQHFRQLNSPLHGLERFP 249

Query: 260 SLESQKERLLSNGWETASAVDMMELYN-RLPRAEVSRIESLEFLDEMELLEQLMRHYCLC 318
            +E+Q+ R L  GW    AVDM E Y+  LP  E  R+E++E  DE E       HY + 
Sbjct: 250 DVEAQRRRFLQAGWTACGAVDMNEFYHCFLPAEERRRVENIEPFDEFEEWHLKCAHYFIL 309

Query: 319 WATKG 323
            A++G
Sbjct: 310 AASRG 314


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 33.1 bits (74), Expect = 0.36
 Identities = 27/113 (23%), Positives = 53/113 (46%), Gaps = 8/113 (7%)

Query: 207  EQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLRRRQCDLAGVETCKSLESQKE 266
            +Q +  LK  +   E+   +  E  N     G+  IE L++   D+       +LE Q +
Sbjct: 916  KQLSEKLKEESEQKEQLRRLKNEMENERWHLGKT-IEKLQKEMADIVEASRTSTLELQNQ 974

Query: 267  RLLSNGWETASAVDMMELYNRLPR----AEVSRIESLEFLDEMELLEQLMRHY 315
                + ++  +  ++ E+  +L      AE SR+ +++  DEM L+E+ +R Y
Sbjct: 975  L---DEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDY 1024


>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
          Length = 495

 Score = 29.6 bits (65), Expect = 3.9
 Identities = 26/116 (22%), Positives = 49/116 (42%), Gaps = 12/116 (10%)

Query: 113 LLPSKYFEVDFPMIVTRKLHSIKCKPPLSSPILELHSEDTLQMD------GHILDSKRYA 166
           LL ++ FE+D    + +   + + K       L+L  E+ L M+        + D K   
Sbjct: 59  LLQNEQFELDMEEAIQKAEENKRLKE------LQLKQEEKLAMELAKLKHESLKDEKMRQ 112

Query: 167 VIGADLRDLSELEEKLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFER 222
            +  +  +L ELE+KLK   MN +    +  +  + Y   ++ A + K      +R
Sbjct: 113 QVRENSIELRELEKKLKAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHKR 168


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 5/66 (7%)

Query: 250 CDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLEFLDEMELLE 309
           CDLAG E     +++ ERL   G    S + + +  N L  +E S+     F   +   E
Sbjct: 379 CDLAGSERTMKTQNEGERLRETGNINTSLLTLGKCINVLKNSEKSK-----FQQHVPFRE 433

Query: 310 QLMRHY 315
             + HY
Sbjct: 434 SKLTHY 439


>gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5
           [Homo sapiens]
          Length = 502

 Score = 28.5 bits (62), Expect = 8.8
 Identities = 23/100 (23%), Positives = 48/100 (48%), Gaps = 2/100 (2%)

Query: 196 IAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLRRRQCDLAGV 255
           + E + V + P+ + N L  + N  +++  +N +Q +  D F Q+MI++   ++ +    
Sbjct: 232 VFEALNVSLFPKDTINFLSKSVNRMKKSR-LNDKQKHRLD-FLQLMIDSQNSKETESHKA 289

Query: 256 ETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSR 295
            +   L +Q    +  G+ET S+V    LY      +V +
Sbjct: 290 LSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQ 329


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,266,285
Number of Sequences: 37866
Number of extensions: 506719
Number of successful extensions: 1189
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1182
Number of HSP's gapped (non-prelim): 8
length of query: 334
length of database: 18,247,518
effective HSP length: 103
effective length of query: 231
effective length of database: 14,347,320
effective search space: 3314230920
effective search space used: 3314230920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.