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Search of human proteins with 73858566
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|73858566 heparin cofactor II precursor [Homo sapiens]
(499 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|73858566 heparin cofactor II precursor [Homo sapiens] 999 0.0
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 210 2e-54
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 198 1e-50
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 189 4e-48
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 187 1e-47
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 183 3e-46
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 183 3e-46
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 183 3e-46
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 183 3e-46
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 183 3e-46
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 183 3e-46
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 183 3e-46
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 183 3e-46
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo... 183 3e-46
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo... 183 3e-46
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo... 183 3e-46
gi|73858564 corticosteroid binding globulin precursor [Homo sapi... 182 5e-46
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (... 181 1e-45
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (... 181 1e-45
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ... 181 1e-45
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a... 181 1e-45
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 181 1e-45
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ... 180 3e-45
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o... 180 3e-45
gi|170295807 neuroserpin precursor [Homo sapiens] 177 2e-44
gi|4826904 neuroserpin precursor [Homo sapiens] 177 2e-44
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (... 176 4e-44
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 174 2e-43
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom... 174 2e-43
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s... 173 4e-43
>gi|73858566 heparin cofactor II precursor [Homo sapiens]
Length = 499
Score = 999 bits (2584), Expect = 0.0
Identities = 499/499 (100%), Positives = 499/499 (100%)
Query: 1 MKHSLNALLIFLIITSAWGGSKGPLDQLEKGGETAQSADPQWEQLNNKNLSMPLLPADFH 60
MKHSLNALLIFLIITSAWGGSKGPLDQLEKGGETAQSADPQWEQLNNKNLSMPLLPADFH
Sbjct: 1 MKHSLNALLIFLIITSAWGGSKGPLDQLEKGGETAQSADPQWEQLNNKNLSMPLLPADFH 60
Query: 61 KENTVTNDWIPEGEEDDDYLDLEKIFSEDDDYIDIVDSLSVSPTDSDVSAGNILQLFHGK 120
KENTVTNDWIPEGEEDDDYLDLEKIFSEDDDYIDIVDSLSVSPTDSDVSAGNILQLFHGK
Sbjct: 61 KENTVTNDWIPEGEEDDDYLDLEKIFSEDDDYIDIVDSLSVSPTDSDVSAGNILQLFHGK 120
Query: 121 SRIQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSI 180
SRIQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSI
Sbjct: 121 SRIQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSI 180
Query: 181 LHFKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKV 240
LHFKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKV
Sbjct: 181 LHFKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKV 240
Query: 241 REYYFAEAQIADFSDPAFISKTNNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWV 300
REYYFAEAQIADFSDPAFISKTNNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWV
Sbjct: 241 REYYFAEAQIADFSDPAFISKTNNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWV 300
Query: 301 NKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVP 360
NKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVP
Sbjct: 301 NKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVP 360
Query: 361 HKMSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK 420
HKMSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK
Sbjct: 361 HKMSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK 420
Query: 421 NGNMAGISDQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIY 480
NGNMAGISDQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIY
Sbjct: 421 NGNMAGISDQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIY 480
Query: 481 EHRTSCLLFMGRVANPSRS 499
EHRTSCLLFMGRVANPSRS
Sbjct: 481 EHRTSCLLFMGRVANPSRS 499
>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
A [Homo sapiens]
Length = 435
Score = 210 bits (535), Expect = 2e-54
Identities = 134/378 (35%), Positives = 206/378 (54%), Gaps = 14/378 (3%)
Query: 129 LNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVN 188
LN FAF LYR L + + NIF +PV +ST++ M+SLG T Q+ L F N
Sbjct: 65 LNTDFAFRLYRRLVLETPS-QNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGF----N 119
Query: 189 ASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEA 248
+ E + IH F+ L H L + TL+ + L+++K+ + +F V+ Y AE
Sbjct: 120 LTHTPE-SAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEV 178
Query: 249 QIADFSDPAFI-SKTNNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEM 307
DFS+P+ ++ N+H+ K T+G + D ++ +D T M+++N I+FK W F E
Sbjct: 179 FSTDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEY 238
Query: 308 TH-NHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGM 366
T N F + E+ V V MM K F D EL+C +LQ++Y G V+P K M
Sbjct: 239 TRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-GKM 297
Query: 367 KTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAG 426
+ LE L+ R + +W S+ R EV +P+F + +YNL L MGI+ +FDKN + +G
Sbjct: 298 RQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSG 357
Query: 427 ISDQ-RIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQ--VRFTV--DRPFLFLIYE 481
I+ + + + H+ + V+EEGT+AT TT F+ S FTV +R FL +I
Sbjct: 358 IAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITN 417
Query: 482 HRTSCLLFMGRVANPSRS 499
T +LF+G+V NP++S
Sbjct: 418 KATDGILFLGKVENPTKS 435
>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1 [Homo sapiens]
Length = 379
Score = 198 bits (503), Expect = 1e-50
Identities = 128/389 (32%), Positives = 209/389 (53%), Gaps = 25/389 (6%)
Query: 123 IQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILH 182
+++L+ N +FA +L+ L + N NIFI+P IS+AM M+ LG +G T Q+ H
Sbjct: 1 MEQLSSANTRFALDLFLALSEN-NPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFH 59
Query: 183 FKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVRE 242
F + +H+ F+ L + +R Y L+ N LY +K + L +F ++
Sbjct: 60 FNT---------VEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQK 110
Query: 243 YYFAEAQIADFSDPAFISKT--NNHIMKLTKGLIKDALEN--IDPATQMMILNCIYFKGS 298
Y A+ DF + ++ N + T+G I + L + +D T+++++N IYFKG+
Sbjct: 111 TYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGN 170
Query: 299 WVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVG-GISMLI 357
W +KF E T N FRLN+++ V MM K F ++L C +L+L Y G +SM+I
Sbjct: 171 WKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVI 230
Query: 358 VVP----HKMSGMKTLEAQLTPRVVERWQK--SMTNRTREVLLPKFKLEKNYNLVESLKL 411
++P + +G+K +E QLT + W K ++ V LP+FKLE++Y L L
Sbjct: 231 LLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLAR 290
Query: 412 MGIRMLFDKN-GNMAGISDQR-IAIDLFKHQGTITVNEEGTQATTVTT--VGFMPLSTQV 467
+G++ LF+ + +++G+S R I I H+ + VNEEGT+A T F L +
Sbjct: 291 LGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEE 350
Query: 468 RFTVDRPFLFLIYEHRTSCLLFMGRVANP 496
FT D PFLF I + + +LF+GR ++P
Sbjct: 351 NFTADHPFLFFIRHNSSGSILFLGRFSSP 379
>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 3 [Homo sapiens]
Length = 390
Score = 189 bits (481), Expect = 4e-48
Identities = 112/389 (28%), Positives = 214/389 (55%), Gaps = 20/389 (5%)
Query: 126 LNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHF-- 183
L+ N KF F+L++ + +NIF +P+ I++A+GM+ LG K T +Q+ +LHF
Sbjct: 4 LSEANTKFMFDLFQQFRKSKE--NNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQ 61
Query: 184 --KDFVNASSKYEIT---TIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKT 238
++ ++ Y + +H+ F+KL + Y L+ N L+ +K + L ++
Sbjct: 62 VTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLD 121
Query: 239 KVREYYFAEAQIADFSDPAFIS--KTNNHIMKLTKGLIKDALE--NIDPATQMMILNCIY 294
++++Y + DF++ S K N+ + T IK+ + NI T ++++N IY
Sbjct: 122 AIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIY 181
Query: 295 FKGSWVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVG-GI 353
FKG W KF E T F N+ + MM+ +F A+ +++ +L++ Y G +
Sbjct: 182 FKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDL 241
Query: 354 SMLIVVPHKMSGMKTLEAQLTPRVVERWQ--KSMTNRTREVLLPKFKLEKNYNLVESLKL 411
SM++++P+++ G++ LE +LT + W ++M ++ LP+FK+E++Y+L ++L+
Sbjct: 242 SMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRT 301
Query: 412 MGIRMLFDKNGNMAGISDQR-IAIDLFKHQGTITVNEEGTQATTVTTV---GFMPLSTQV 467
MG+ +F+ + +++G++ R + + H+ + V EEG +A T V G P ST
Sbjct: 302 MGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNE 361
Query: 468 RFTVDRPFLFLIYEHRTSCLLFMGRVANP 496
F + PFLF I +++T+ +LF GR ++P
Sbjct: 362 EFHCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 187 bits (476), Expect = 1e-47
Identities = 111/389 (28%), Positives = 211/389 (54%), Gaps = 20/389 (5%)
Query: 126 LNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKD 185
L+ N KF F+L++ + +NIF +P+ I++A+GM+ LG K T +Q+ +LHF
Sbjct: 4 LSEANTKFMFDLFQQFRKSKE--NNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQ 61
Query: 186 FVNASSKYEIT-------TIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKT 238
+++ T +H+ F+KL + Y L+ N L+ +K + L ++
Sbjct: 62 VTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLD 121
Query: 239 KVREYYFAEAQIADFSDPAFIS--KTNNHIMKLTKGLIKDALEN--IDPATQMMILNCIY 294
++++Y + DF++ S K N+ + T IK+ + I T ++++N IY
Sbjct: 122 AIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIY 181
Query: 295 FKGSWVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVG-GI 353
FKG W NKF E T F N+ V MM+ +F A +++ +L++ Y G +
Sbjct: 182 FKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDL 241
Query: 354 SMLIVVPHKMSGMKTLEAQLTPRVVERWQ--KSMTNRTREVLLPKFKLEKNYNLVESLKL 411
SM++++P+++ G++ LE +LT + W ++M ++ LP+FK+E++Y+L ++L+
Sbjct: 242 SMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRT 301
Query: 412 MGIRMLFDKNGNMAGIS-DQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPL---STQV 467
MG+ +F+ + +++G++ +++ H+ + V EEG +A T V + L ST
Sbjct: 302 MGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNE 361
Query: 468 RFTVDRPFLFLIYEHRTSCLLFMGRVANP 496
F + PFLF I +++T+ +LF GR ++P
Sbjct: 362 EFCCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 183 bits (465), Expect = 3e-46
Identities = 109/370 (29%), Positives = 203/370 (54%), Gaps = 9/370 (2%)
Query: 131 AKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNAS 190
A+FAF+LYR L Q N+ NIF +PV I+TA M+SLG K +TH+++ L+F
Sbjct: 55 AEFAFSLYRQLAHQSNS-TNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN-----L 108
Query: 191 SKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250
++ IH F++L L + + L + N L++ + ++ F V++ Y +EA
Sbjct: 109 TEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT 168
Query: 251 ADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTH 309
+F D K N+++ K T+G I D ++ +D T ++N I+FKG W F V+ T
Sbjct: 169 VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTE 228
Query: 310 NHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTL 369
+F +++ VKV MM+ G F + ++L +L ++Y+G + + +P + ++ L
Sbjct: 229 EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE-GKLQHL 287
Query: 370 EAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISD 429
E +LT ++ ++ ++ R+ + LPK + Y+L L +GI +F +++G+++
Sbjct: 288 ENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTE 347
Query: 430 QR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLL 488
+ + + H+ +T++E+GT+A + +P+S ++PF+FL+ E T L
Sbjct: 348 EAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPL 407
Query: 489 FMGRVANPSR 498
FMG+V NP++
Sbjct: 408 FMGKVVNPTQ 417
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 183 bits (465), Expect = 3e-46
Identities = 109/370 (29%), Positives = 203/370 (54%), Gaps = 9/370 (2%)
Query: 131 AKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNAS 190
A+FAF+LYR L Q N+ NIF +PV I+TA M+SLG K +TH+++ L+F
Sbjct: 55 AEFAFSLYRQLAHQSNS-TNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN-----L 108
Query: 191 SKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250
++ IH F++L L + + L + N L++ + ++ F V++ Y +EA
Sbjct: 109 TEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT 168
Query: 251 ADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTH 309
+F D K N+++ K T+G I D ++ +D T ++N I+FKG W F V+ T
Sbjct: 169 VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTE 228
Query: 310 NHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTL 369
+F +++ VKV MM+ G F + ++L +L ++Y+G + + +P + ++ L
Sbjct: 229 EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE-GKLQHL 287
Query: 370 EAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISD 429
E +LT ++ ++ ++ R+ + LPK + Y+L L +GI +F +++G+++
Sbjct: 288 ENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTE 347
Query: 430 QR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLL 488
+ + + H+ +T++E+GT+A + +P+S ++PF+FL+ E T L
Sbjct: 348 EAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPL 407
Query: 489 FMGRVANPSR 498
FMG+V NP++
Sbjct: 408 FMGKVVNPTQ 417
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 183 bits (465), Expect = 3e-46
Identities = 109/370 (29%), Positives = 203/370 (54%), Gaps = 9/370 (2%)
Query: 131 AKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNAS 190
A+FAF+LYR L Q N+ NIF +PV I+TA M+SLG K +TH+++ L+F
Sbjct: 55 AEFAFSLYRQLAHQSNS-TNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN-----L 108
Query: 191 SKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250
++ IH F++L L + + L + N L++ + ++ F V++ Y +EA
Sbjct: 109 TEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT 168
Query: 251 ADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTH 309
+F D K N+++ K T+G I D ++ +D T ++N I+FKG W F V+ T
Sbjct: 169 VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTE 228
Query: 310 NHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTL 369
+F +++ VKV MM+ G F + ++L +L ++Y+G + + +P + ++ L
Sbjct: 229 EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE-GKLQHL 287
Query: 370 EAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISD 429
E +LT ++ ++ ++ R+ + LPK + Y+L L +GI +F +++G+++
Sbjct: 288 ENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTE 347
Query: 430 QR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLL 488
+ + + H+ +T++E+GT+A + +P+S ++PF+FL+ E T L
Sbjct: 348 EAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPL 407
Query: 489 FMGRVANPSR 498
FMG+V NP++
Sbjct: 408 FMGKVVNPTQ 417
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 183 bits (465), Expect = 3e-46
Identities = 109/370 (29%), Positives = 203/370 (54%), Gaps = 9/370 (2%)
Query: 131 AKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNAS 190
A+FAF+LYR L Q N+ NIF +PV I+TA M+SLG K +TH+++ L+F
Sbjct: 55 AEFAFSLYRQLAHQSNS-TNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN-----L 108
Query: 191 SKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250
++ IH F++L L + + L + N L++ + ++ F V++ Y +EA
Sbjct: 109 TEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT 168
Query: 251 ADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTH 309
+F D K N+++ K T+G I D ++ +D T ++N I+FKG W F V+ T
Sbjct: 169 VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTE 228
Query: 310 NHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTL 369
+F +++ VKV MM+ G F + ++L +L ++Y+G + + +P + ++ L
Sbjct: 229 EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE-GKLQHL 287
Query: 370 EAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISD 429
E +LT ++ ++ ++ R+ + LPK + Y+L L +GI +F +++G+++
Sbjct: 288 ENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTE 347
Query: 430 QR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLL 488
+ + + H+ +T++E+GT+A + +P+S ++PF+FL+ E T L
Sbjct: 348 EAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPL 407
Query: 489 FMGRVANPSR 498
FMG+V NP++
Sbjct: 408 FMGKVVNPTQ 417
>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 183 bits (465), Expect = 3e-46
Identities = 109/370 (29%), Positives = 203/370 (54%), Gaps = 9/370 (2%)
Query: 131 AKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNAS 190
A+FAF+LYR L Q N+ NIF +PV I+TA M+SLG K +TH+++ L+F
Sbjct: 55 AEFAFSLYRQLAHQSNS-TNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN-----L 108
Query: 191 SKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250
++ IH F++L L + + L + N L++ + ++ F V++ Y +EA
Sbjct: 109 TEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT 168
Query: 251 ADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTH 309
+F D K N+++ K T+G I D ++ +D T ++N I+FKG W F V+ T
Sbjct: 169 VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTE 228
Query: 310 NHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTL 369
+F +++ VKV MM+ G F + ++L +L ++Y+G + + +P + ++ L
Sbjct: 229 EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE-GKLQHL 287
Query: 370 EAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISD 429
E +LT ++ ++ ++ R+ + LPK + Y+L L +GI +F +++G+++
Sbjct: 288 ENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTE 347
Query: 430 QR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLL 488
+ + + H+ +T++E+GT+A + +P+S ++PF+FL+ E T L
Sbjct: 348 EAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPL 407
Query: 489 FMGRVANPSR 498
FMG+V NP++
Sbjct: 408 FMGKVVNPTQ 417
>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 183 bits (465), Expect = 3e-46
Identities = 109/370 (29%), Positives = 203/370 (54%), Gaps = 9/370 (2%)
Query: 131 AKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNAS 190
A+FAF+LYR L Q N+ NIF +PV I+TA M+SLG K +TH+++ L+F
Sbjct: 55 AEFAFSLYRQLAHQSNS-TNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN-----L 108
Query: 191 SKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250
++ IH F++L L + + L + N L++ + ++ F V++ Y +EA
Sbjct: 109 TEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT 168
Query: 251 ADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTH 309
+F D K N+++ K T+G I D ++ +D T ++N I+FKG W F V+ T
Sbjct: 169 VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTE 228
Query: 310 NHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTL 369
+F +++ VKV MM+ G F + ++L +L ++Y+G + + +P + ++ L
Sbjct: 229 EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE-GKLQHL 287
Query: 370 EAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISD 429
E +LT ++ ++ ++ R+ + LPK + Y+L L +GI +F +++G+++
Sbjct: 288 ENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTE 347
Query: 430 QR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLL 488
+ + + H+ +T++E+GT+A + +P+S ++PF+FL+ E T L
Sbjct: 348 EAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPL 407
Query: 489 FMGRVANPSR 498
FMG+V NP++
Sbjct: 408 FMGKVVNPTQ 417
>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 183 bits (465), Expect = 3e-46
Identities = 109/370 (29%), Positives = 203/370 (54%), Gaps = 9/370 (2%)
Query: 131 AKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNAS 190
A+FAF+LYR L Q N+ NIF +PV I+TA M+SLG K +TH+++ L+F
Sbjct: 55 AEFAFSLYRQLAHQSNS-TNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN-----L 108
Query: 191 SKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250
++ IH F++L L + + L + N L++ + ++ F V++ Y +EA
Sbjct: 109 TEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT 168
Query: 251 ADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTH 309
+F D K N+++ K T+G I D ++ +D T ++N I+FKG W F V+ T
Sbjct: 169 VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTE 228
Query: 310 NHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTL 369
+F +++ VKV MM+ G F + ++L +L ++Y+G + + +P + ++ L
Sbjct: 229 EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE-GKLQHL 287
Query: 370 EAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISD 429
E +LT ++ ++ ++ R+ + LPK + Y+L L +GI +F +++G+++
Sbjct: 288 ENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTE 347
Query: 430 QR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLL 488
+ + + H+ +T++E+GT+A + +P+S ++PF+FL+ E T L
Sbjct: 348 EAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPL 407
Query: 489 FMGRVANPSR 498
FMG+V NP++
Sbjct: 408 FMGKVVNPTQ 417
>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 183 bits (465), Expect = 3e-46
Identities = 109/370 (29%), Positives = 203/370 (54%), Gaps = 9/370 (2%)
Query: 131 AKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNAS 190
A+FAF+LYR L Q N+ NIF +PV I+TA M+SLG K +TH+++ L+F
Sbjct: 55 AEFAFSLYRQLAHQSNS-TNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN-----L 108
Query: 191 SKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250
++ IH F++L L + + L + N L++ + ++ F V++ Y +EA
Sbjct: 109 TEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT 168
Query: 251 ADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTH 309
+F D K N+++ K T+G I D ++ +D T ++N I+FKG W F V+ T
Sbjct: 169 VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTE 228
Query: 310 NHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTL 369
+F +++ VKV MM+ G F + ++L +L ++Y+G + + +P + ++ L
Sbjct: 229 EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE-GKLQHL 287
Query: 370 EAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISD 429
E +LT ++ ++ ++ R+ + LPK + Y+L L +GI +F +++G+++
Sbjct: 288 ENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTE 347
Query: 430 QR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLL 488
+ + + H+ +T++E+GT+A + +P+S ++PF+FL+ E T L
Sbjct: 348 EAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPL 407
Query: 489 FMGRVANPSR 498
FMG+V NP++
Sbjct: 408 FMGKVVNPTQ 417
>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 183 bits (465), Expect = 3e-46
Identities = 109/370 (29%), Positives = 203/370 (54%), Gaps = 9/370 (2%)
Query: 131 AKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNAS 190
A+FAF+LYR L Q N+ NIF +PV I+TA M+SLG K +TH+++ L+F
Sbjct: 55 AEFAFSLYRQLAHQSNS-TNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN-----L 108
Query: 191 SKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250
++ IH F++L L + + L + N L++ + ++ F V++ Y +EA
Sbjct: 109 TEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT 168
Query: 251 ADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTH 309
+F D K N+++ K T+G I D ++ +D T ++N I+FKG W F V+ T
Sbjct: 169 VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTE 228
Query: 310 NHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTL 369
+F +++ VKV MM+ G F + ++L +L ++Y+G + + +P + ++ L
Sbjct: 229 EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE-GKLQHL 287
Query: 370 EAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISD 429
E +LT ++ ++ ++ R+ + LPK + Y+L L +GI +F +++G+++
Sbjct: 288 ENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTE 347
Query: 430 QR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLL 488
+ + + H+ +T++E+GT+A + +P+S ++PF+FL+ E T L
Sbjct: 348 EAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPL 407
Query: 489 FMGRVANPSR 498
FMG+V NP++
Sbjct: 408 FMGKVVNPTQ 417
>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 183 bits (465), Expect = 3e-46
Identities = 109/370 (29%), Positives = 203/370 (54%), Gaps = 9/370 (2%)
Query: 131 AKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNAS 190
A+FAF+LYR L Q N+ NIF +PV I+TA M+SLG K +TH+++ L+F
Sbjct: 55 AEFAFSLYRQLAHQSNS-TNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN-----L 108
Query: 191 SKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250
++ IH F++L L + + L + N L++ + ++ F V++ Y +EA
Sbjct: 109 TEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT 168
Query: 251 ADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTH 309
+F D K N+++ K T+G I D ++ +D T ++N I+FKG W F V+ T
Sbjct: 169 VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTE 228
Query: 310 NHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTL 369
+F +++ VKV MM+ G F + ++L +L ++Y+G + + +P + ++ L
Sbjct: 229 EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE-GKLQHL 287
Query: 370 EAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISD 429
E +LT ++ ++ ++ R+ + LPK + Y+L L +GI +F +++G+++
Sbjct: 288 ENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTE 347
Query: 430 QR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLL 488
+ + + H+ +T++E+GT+A + +P+S ++PF+FL+ E T L
Sbjct: 348 EAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPL 407
Query: 489 FMGRVANPSR 498
FMG+V NP++
Sbjct: 408 FMGKVVNPTQ 417
>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 183 bits (465), Expect = 3e-46
Identities = 109/370 (29%), Positives = 203/370 (54%), Gaps = 9/370 (2%)
Query: 131 AKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNAS 190
A+FAF+LYR L Q N+ NIF +PV I+TA M+SLG K +TH+++ L+F
Sbjct: 55 AEFAFSLYRQLAHQSNS-TNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN-----L 108
Query: 191 SKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250
++ IH F++L L + + L + N L++ + ++ F V++ Y +EA
Sbjct: 109 TEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT 168
Query: 251 ADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTH 309
+F D K N+++ K T+G I D ++ +D T ++N I+FKG W F V+ T
Sbjct: 169 VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTE 228
Query: 310 NHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTL 369
+F +++ VKV MM+ G F + ++L +L ++Y+G + + +P + ++ L
Sbjct: 229 EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE-GKLQHL 287
Query: 370 EAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISD 429
E +LT ++ ++ ++ R+ + LPK + Y+L L +GI +F +++G+++
Sbjct: 288 ENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTE 347
Query: 430 QR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLL 488
+ + + H+ +T++E+GT+A + +P+S ++PF+FL+ E T L
Sbjct: 348 EAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPL 407
Query: 489 FMGRVANPSR 498
FMG+V NP++
Sbjct: 408 FMGKVVNPTQ 417
>gi|73858564 corticosteroid binding globulin precursor [Homo
sapiens]
Length = 405
Score = 182 bits (463), Expect = 5e-46
Identities = 118/370 (31%), Positives = 190/370 (51%), Gaps = 11/370 (2%)
Query: 130 NAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNA 189
N FAF+LY+ L ++ NIFI+PV IS A+ M+SLG G T Q+ L F N
Sbjct: 43 NVDFAFSLYKHLV-ALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGF----NL 97
Query: 190 SSKYEITTIHNLFRKLTHRLFRRN-FGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEA 248
+ + E T IH F+ L H+LF ++ + N L++ +L F ++ YY +E
Sbjct: 98 TERSE-TEIHQGFQHL-HQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEV 155
Query: 249 QIADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEM 307
+F D A S+ N+++ T+G I D +D ++++N I+FKG+W F +
Sbjct: 156 LAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLAS 215
Query: 308 THNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMK 367
T NF ++E VVKV MM +D EL C ++Q+ YVG ++ ++P K M
Sbjct: 216 TREENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDK-GKMN 274
Query: 368 TLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGI 427
T+ A L+ + RW +T+ ++ +PK + Y+L + L+ MGI LF N + I
Sbjct: 275 TVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRI 334
Query: 428 S-DQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSC 486
+ D ++ H+ + +NEEG T V S + ++PF+ +I++H T
Sbjct: 335 TQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWS 394
Query: 487 LLFMGRVANP 496
LF+ RV NP
Sbjct: 395 SLFLARVMNP 404
>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 181 bits (460), Expect = 1e-45
Identities = 119/378 (31%), Positives = 202/378 (53%), Gaps = 22/378 (5%)
Query: 130 NAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNA 189
N FA +L+++L ++ N+ N+F +P+ IS+A+ M+ +G KG T Q+ L
Sbjct: 8 NGTFAISLFKILGEEDNS-RNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL------ 60
Query: 190 SSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQ 249
Y+ IH F+ L + R Y LR+ N L+ +K L DFK +++Y AE +
Sbjct: 61 ---YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE 117
Query: 250 IADFSDPAFISKT--NNHIMKLTKGLIKDALE--NIDPATQMMILNCIYFKGSWVNKFPV 305
F++ + N+ + + T+G I + L+ +DP T+++++N IYFKG W +F
Sbjct: 118 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR 177
Query: 306 EMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGG-ISMLIVVPHKMS 364
+ T F+ NE E V MM + F E+ +L+L YV +SM+I++P +
Sbjct: 178 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT 236
Query: 365 GMKTLEAQLTPRVVERWQKS--MTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK-N 421
+ +E LT + W S +T +V LP+ KLE++Y+L L+ +G+ FD+
Sbjct: 237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296
Query: 422 GNMAGISDQR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQV--RFTVDRPFLFL 478
+ +G+S ++ + + H+ + VNEEGT+A T V +++ RF D PFLF
Sbjct: 297 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF 356
Query: 479 IYEHRTSCLLFMGRVANP 496
I H+T+C+LF GR ++P
Sbjct: 357 IRHHKTNCILFCGRFSSP 374
>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 181 bits (460), Expect = 1e-45
Identities = 119/378 (31%), Positives = 202/378 (53%), Gaps = 22/378 (5%)
Query: 130 NAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNA 189
N FA +L+++L ++ N+ N+F +P+ IS+A+ M+ +G KG T Q+ L
Sbjct: 8 NGTFAISLFKILGEEDNS-RNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL------ 60
Query: 190 SSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQ 249
Y+ IH F+ L + R Y LR+ N L+ +K L DFK +++Y AE +
Sbjct: 61 ---YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE 117
Query: 250 IADFSDPAFISKT--NNHIMKLTKGLIKDALE--NIDPATQMMILNCIYFKGSWVNKFPV 305
F++ + N+ + + T+G I + L+ +DP T+++++N IYFKG W +F
Sbjct: 118 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR 177
Query: 306 EMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGG-ISMLIVVPHKMS 364
+ T F+ NE E V MM + F E+ +L+L YV +SM+I++P +
Sbjct: 178 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT 236
Query: 365 GMKTLEAQLTPRVVERWQKS--MTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK-N 421
+ +E LT + W S +T +V LP+ KLE++Y+L L+ +G+ FD+
Sbjct: 237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296
Query: 422 GNMAGISDQR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQV--RFTVDRPFLFL 478
+ +G+S ++ + + H+ + VNEEGT+A T V +++ RF D PFLF
Sbjct: 297 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF 356
Query: 479 IYEHRTSCLLFMGRVANP 496
I H+T+C+LF GR ++P
Sbjct: 357 IRHHKTNCILFCGRFSSP 374
>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 181 bits (460), Expect = 1e-45
Identities = 120/377 (31%), Positives = 186/377 (49%), Gaps = 10/377 (2%)
Query: 124 QRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHF 183
Q+L + F F+L R K + N+ +P G+S AM + LG G T Q+ LH
Sbjct: 73 QQLAKETSNFGFSLLR--KISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHL 130
Query: 184 KDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREY 243
+ A + + +LF+ L L RN L + +I K F + F + Y
Sbjct: 131 Q----ALKPTKPGLLPSLFKGLRETL-SRNLELGLTQGSFAFIHKDFDVKETFFNLSKRY 185
Query: 244 YFAEAQIADFSDPAFISKTNNH-IMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNK 302
+ E +F + + + NH I K T+G I + I+P T++++++ I FKG W+
Sbjct: 186 FDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTP 245
Query: 303 FPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHK 362
F T F L++ + +KV MM G F + D+ C +L+L Y G +ML+V+ K
Sbjct: 246 FDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEK 305
Query: 363 MSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNG 422
M LE LT +VE W ++M R EV PKFKL++ Y + E L+ MGIR +F
Sbjct: 306 MGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFA 365
Query: 423 NMAGIS--DQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIY 480
+++ +S + + + + I V+E GT+A S VDRPF F+IY
Sbjct: 366 DLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIY 425
Query: 481 EHRTSCLLFMGRVANPS 497
E + LLF+GRV NP+
Sbjct: 426 EETSGMLLFLGRVVNPT 442
>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 181 bits (460), Expect = 1e-45
Identities = 120/377 (31%), Positives = 186/377 (49%), Gaps = 10/377 (2%)
Query: 124 QRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHF 183
Q+L + F F+L R K + N+ +P G+S AM + LG G T Q+ LH
Sbjct: 73 QQLAKETSNFGFSLLR--KISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHL 130
Query: 184 KDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREY 243
+ A + + +LF+ L L RN L + +I K F + F + Y
Sbjct: 131 Q----ALKPTKPGLLPSLFKGLRETL-SRNLELGLTQGSFAFIHKDFDVKETFFNLSKRY 185
Query: 244 YFAEAQIADFSDPAFISKTNNH-IMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNK 302
+ E +F + + + NH I K T+G I + I+P T++++++ I FKG W+
Sbjct: 186 FDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTP 245
Query: 303 FPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHK 362
F T F L++ + +KV MM G F + D+ C +L+L Y G +ML+V+ K
Sbjct: 246 FDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEK 305
Query: 363 MSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNG 422
M LE LT +VE W ++M R EV PKFKL++ Y + E L+ MGIR +F
Sbjct: 306 MGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFA 365
Query: 423 NMAGIS--DQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIY 480
+++ +S + + + + I V+E GT+A S VDRPF F+IY
Sbjct: 366 DLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIY 425
Query: 481 EHRTSCLLFMGRVANPS 497
E + LLF+GRV NP+
Sbjct: 426 EETSGMLLFLGRVVNPT 442
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 181 bits (459), Expect = 1e-45
Identities = 122/380 (32%), Positives = 200/380 (52%), Gaps = 19/380 (5%)
Query: 130 NAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNA 189
N FAF+LY+ L + N+ +P+ ISTA+ +SLG T ++ L F +
Sbjct: 53 NVDFAFSLYKQLVLKAPD-KNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFN--LTE 109
Query: 190 SSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQ 249
+S+ EI H F+ L L + + L N +++++Q +L F + Y +EA
Sbjct: 110 TSEAEI---HQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAF 166
Query: 250 IADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMT 308
DF D A K N+++ T+G I D ++++D T M+++N I+FK W F + T
Sbjct: 167 ATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDT 226
Query: 309 HNHNFRLNEREVVKVSMMQTKGNFLA-ANDQELDCDILQLEYVGGISMLIVVPHKMSGMK 367
H F L++++ V V MM + D+EL C +++L+Y G S L ++P + M+
Sbjct: 227 HQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQ-DKME 285
Query: 368 TLEAQLTPRVVERWQKSMTNR-TREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAG 426
+EA L P ++RW+ S+ R E+ LPKF + ++YNL + L +GI F +++G
Sbjct: 286 EVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSG 345
Query: 427 ISDQR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLS------TQVRFTVDRPFLFLI 479
I+ R +A+ H+ + V EEGT+A+ T V LS T VRF +RPFL +I
Sbjct: 346 ITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRF--NRPFLMII 403
Query: 480 YEHRTSCLLFMGRVANPSRS 499
T + FM +V NP ++
Sbjct: 404 VPTDTQNIFFMSKVTNPKQA 423
>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 180 bits (456), Expect = 3e-45
Identities = 129/421 (30%), Positives = 212/421 (50%), Gaps = 53/421 (12%)
Query: 123 IQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILH 182
++ L + N FA NL++ L T N+F++P IS+ M M+ +G +G T +Q+ +L
Sbjct: 1 MEDLCVANTLFALNLFKHLAKASPT-QNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQ 59
Query: 183 FKDFVNASSKYEITT-----------------------------IHNLFRKLTHRLFRRN 213
F + V A++ +T IH+ FR L+ +
Sbjct: 60 FNE-VGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINAST 118
Query: 214 FGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQIADFSDPAFIS--KTNNHIMKLTK 271
Y L SVN L+ +K ++ ++YY +E Q DF + A + K N+ + TK
Sbjct: 119 GNYLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTK 178
Query: 272 GLIKDALE--NIDPATQMMILNCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVSMMQTK 329
G I + L ++D T+M+++N +YFKG W F ++ + FR+N + V MM +
Sbjct: 179 GKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLR 238
Query: 330 GNFLAANDQELDCDILQLEYVGGISMLIVVPHKM----SGMKTLEAQLTPRVVERW--QK 383
++L IL+L Y G +SM +++P ++ +G++ LE+++T + +W +
Sbjct: 239 EKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKD 298
Query: 384 SMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK-NGNMAGISDQRIAIDLFK---- 438
M EV +P+FKLE++Y L L+ MG+ F+K N +G+S++ DLF
Sbjct: 299 KMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERN---DLFLSEVF 355
Query: 439 HQGTITVNEEGTQATTVTTVGFMPLST---QVRFTVDRPFLFLIYEHRTSCLLFMGRVAN 495
HQ + VNEEGT+A T G M T +F D PFLFLI T+C+LF GR ++
Sbjct: 356 HQAMVDVNEEGTEA-AAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSS 414
Query: 496 P 496
P
Sbjct: 415 P 415
>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 180 bits (456), Expect = 3e-45
Identities = 129/421 (30%), Positives = 212/421 (50%), Gaps = 53/421 (12%)
Query: 123 IQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILH 182
++ L + N FA NL++ L T N+F++P IS+ M M+ +G +G T +Q+ +L
Sbjct: 1 MEDLCVANTLFALNLFKHLAKASPT-QNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQ 59
Query: 183 FKDFVNASSKYEITT-----------------------------IHNLFRKLTHRLFRRN 213
F + V A++ +T IH+ FR L+ +
Sbjct: 60 FNE-VGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINAST 118
Query: 214 FGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQIADFSDPAFIS--KTNNHIMKLTK 271
Y L SVN L+ +K ++ ++YY +E Q DF + A + K N+ + TK
Sbjct: 119 GNYLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTK 178
Query: 272 GLIKDALE--NIDPATQMMILNCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVSMMQTK 329
G I + L ++D T+M+++N +YFKG W F ++ + FR+N + V MM +
Sbjct: 179 GKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLR 238
Query: 330 GNFLAANDQELDCDILQLEYVGGISMLIVVPHKM----SGMKTLEAQLTPRVVERW--QK 383
++L IL+L Y G +SM +++P ++ +G++ LE+++T + +W +
Sbjct: 239 EKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKD 298
Query: 384 SMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK-NGNMAGISDQRIAIDLFK---- 438
M EV +P+FKLE++Y L L+ MG+ F+K N +G+S++ DLF
Sbjct: 299 KMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERN---DLFLSEVF 355
Query: 439 HQGTITVNEEGTQATTVTTVGFMPLST---QVRFTVDRPFLFLIYEHRTSCLLFMGRVAN 495
HQ + VNEEGT+A T G M T +F D PFLFLI T+C+LF GR ++
Sbjct: 356 HQAMVDVNEEGTEA-AAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSS 414
Query: 496 P 496
P
Sbjct: 415 P 415
>gi|170295807 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 177 bits (450), Expect = 2e-44
Identities = 110/381 (28%), Positives = 197/381 (51%), Gaps = 25/381 (6%)
Query: 131 AKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNAS 190
A + N+Y L+ +NI +P+ I+ AMGM+ LG +G T +++ + + N
Sbjct: 27 ADLSVNMYNRLR-ATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGE 85
Query: 191 SKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250
+ ++ ++ + + Y ++ N L++Q F + +F +++Y+ A
Sbjct: 86 E-------FSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNH 138
Query: 251 ADFSDPAFISK-TNNHIMKLTKGLIKDALE--NIDPATQMMILNCIYFKGSWVNKFPVEM 307
DFS ++ N + T L+KD + + D AT + ++N +YFKG+W ++F E
Sbjct: 139 VDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPEN 198
Query: 308 THNHNFRLNEREVVKVSMMQTKGNFL------AANDQELDCDILQLEYVGG-ISMLIVVP 360
T +F ++ V++ MM +G F +N+ +L++ Y G ISM++V+
Sbjct: 199 TRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLS 258
Query: 361 HKMSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK 420
+ + TLE + ++VE W S+ + EV LP+F +E+ +L + LK +GI +F K
Sbjct: 259 RQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIK 318
Query: 421 NGNMAGISDQR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQV----RFTVDRPF 475
+ N+ G+SD + I + H+ + VNEEG++A V+ G + +S + VD PF
Sbjct: 319 DANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVS--GMIAISRMAVLYPQVIVDHPF 376
Query: 476 LFLIYEHRTSCLLFMGRVANP 496
FLI RT +LFMGRV +P
Sbjct: 377 FFLIRNRRTGTILFMGRVMHP 397
>gi|4826904 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 177 bits (450), Expect = 2e-44
Identities = 110/381 (28%), Positives = 197/381 (51%), Gaps = 25/381 (6%)
Query: 131 AKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNAS 190
A + N+Y L+ +NI +P+ I+ AMGM+ LG +G T +++ + + N
Sbjct: 27 ADLSVNMYNRLR-ATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGE 85
Query: 191 SKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250
+ ++ ++ + + Y ++ N L++Q F + +F +++Y+ A
Sbjct: 86 E-------FSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNH 138
Query: 251 ADFSDPAFISK-TNNHIMKLTKGLIKDALE--NIDPATQMMILNCIYFKGSWVNKFPVEM 307
DFS ++ N + T L+KD + + D AT + ++N +YFKG+W ++F E
Sbjct: 139 VDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPEN 198
Query: 308 THNHNFRLNEREVVKVSMMQTKGNFL------AANDQELDCDILQLEYVGG-ISMLIVVP 360
T +F ++ V++ MM +G F +N+ +L++ Y G ISM++V+
Sbjct: 199 TRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLS 258
Query: 361 HKMSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK 420
+ + TLE + ++VE W S+ + EV LP+F +E+ +L + LK +GI +F K
Sbjct: 259 RQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIK 318
Query: 421 NGNMAGISDQR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQV----RFTVDRPF 475
+ N+ G+SD + I + H+ + VNEEG++A V+ G + +S + VD PF
Sbjct: 319 DANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVS--GMIAISRMAVLYPQVIVDHPF 376
Query: 476 LFLIYEHRTSCLLFMGRVANP 496
FLI RT +LFMGRV +P
Sbjct: 377 FFLIRNRRTGTILFMGRVMHP 397
>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 6 [Homo sapiens]
Length = 376
Score = 176 bits (446), Expect = 4e-44
Identities = 116/378 (30%), Positives = 193/378 (51%), Gaps = 20/378 (5%)
Query: 130 NAKFAFNLYRVL-KDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVN 188
N FA NL + L KD N+F +P+ +S A+ M+ +G KG T Q+ IL F
Sbjct: 8 NGTFALNLLKTLGKDNSK---NVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGG 64
Query: 189 ASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEA 248
IH F+ L + + Y LR N L+ +K L F+ +++Y AE
Sbjct: 65 GGD------IHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEM 118
Query: 249 QIADFSDPAFISKT--NNHIMKLTKGLIKDALE--NIDPATQMMILNCIYFKGSWVNKFP 304
+ DF S+ N + + T+G I + L ++DP T+++++N +YF+G+W +F
Sbjct: 119 EELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFD 178
Query: 305 VEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVG-GISMLIVVPHKM 363
E T F++++ E V MM + F E+ IL L YVG ++M+I++P +
Sbjct: 179 KENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDET 238
Query: 364 SGMKTLEAQLTPRVVERWQK--SMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFD-K 420
+ ++T+E +LT W + M EV LP+FKLE++Y++ L+ +G+ F+
Sbjct: 239 TDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELG 298
Query: 421 NGNMAGISDQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQV--RFTVDRPFLFL 478
+ +G+S +++ H+ + VNEEGT+A T M + RF D PFLF
Sbjct: 299 KADFSGMSQTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFF 358
Query: 479 IYEHRTSCLLFMGRVANP 496
I +T+ +LF GR ++P
Sbjct: 359 IQHSKTNGILFCGRFSSP 376
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 174 bits (441), Expect = 2e-43
Identities = 122/386 (31%), Positives = 198/386 (51%), Gaps = 22/386 (5%)
Query: 123 IQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILH 182
++ L+ + FA L ++L Q N N+F +PV IS+A+ M+ LG KG T Q+
Sbjct: 1 METLSNASGTFAIRLLKILC-QDNPSHNVFCSPVSISSALAMVLLGAKGNTATQM----- 54
Query: 183 FKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVRE 242
A S IH F+ L + + Y LR+ N L+ +K L FK +
Sbjct: 55 ----AQALSLNTEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQ 110
Query: 243 YYFAEAQIADFSDPAFISKT--NNHIMKLTKGLIKDAL--ENIDPATQMMILNCIYFKGS 298
+Y AE + F A S+ N + K T+G I++ L +ID T+++++N IYFKG
Sbjct: 111 FYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGK 170
Query: 299 WVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYV-GGISMLI 357
W F T F++N+ E V MM + F A+ E+ +L+L Y +S+L+
Sbjct: 171 WNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLV 230
Query: 358 VVPHKMSGMKTLEAQLTPRVVERWQK--SMTNRTREVLLPKFKLEKNYNLVESLKLMGIR 415
++P + T+E LT + W K M + EVLLPKFKL+++Y++ L+ +GI
Sbjct: 231 LLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIV 290
Query: 416 MLFDK-NGNMAGISDQR-IAIDLFKHQGTITVNEEGTQATTVTT---VGFMPLSTQVRFT 470
F + +++ +S +R + + F H+ + VNEEGT+A ++ V + + RF
Sbjct: 291 DAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFC 350
Query: 471 VDRPFLFLIYEHRTSCLLFMGRVANP 496
D PFLF I +R + +LF GR ++P
Sbjct: 351 ADHPFLFFIRHNRANSILFCGRFSSP 376
>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
sapiens]
Length = 392
Score = 174 bits (441), Expect = 2e-43
Identities = 120/390 (30%), Positives = 196/390 (50%), Gaps = 20/390 (5%)
Query: 126 LNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKD 185
L+ N +F ++++ L N DNIF + + + A+ M+ LG +GET EQ+ +LHF
Sbjct: 4 LSTANVEFCLDVFKELNSN-NIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSH 62
Query: 186 --------FVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFK 237
F ++ + IH+ F ++ + + TL N LY K +
Sbjct: 63 TVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYL 122
Query: 238 TKVREYYFAEAQIADFSDPAFISKT--NNHIMKLTKGLIKDAL--ENIDPATQMMILNCI 293
+ ++Y A Q DF ++ N + T G + + IDP++ M+++N I
Sbjct: 123 SCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAI 182
Query: 294 YFKGSWVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGG- 352
YFKG W NKF V T F+L+E + V V MM G F A +E +L+L YV
Sbjct: 183 YFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNK 242
Query: 353 ISMLIVVPHKMSGMKTLEAQLTPRVVERWQKS--MTNRTREVLLPKFKLEKNYNLVESLK 410
+SM+I++P ++ +K +E QL W S M R EV LP+FKLE Y L LK
Sbjct: 243 LSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLK 302
Query: 411 LMGIRMLFDK-NGNMAGISDQR-IAIDLFKHQGTITVNEEGTQATTVT--TVGFMPLSTQ 466
+G+ LF++ +++G+S + + + H+ + V+EEGT+A T ++ L +
Sbjct: 303 SLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMR 362
Query: 467 VRFTVDRPFLFLIYEHRTSCLLFMGRVANP 496
+F + PFLF I T+ +LF G++A+P
Sbjct: 363 AQFKANHPFLFFIRHTHTNTILFCGKLASP 392
>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
sapiens]
Length = 464
Score = 173 bits (438), Expect = 4e-43
Identities = 127/389 (32%), Positives = 191/389 (49%), Gaps = 20/389 (5%)
Query: 122 RIQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSIL 181
R+ L+ N++FA Y+ L D N DNIF++P+ ISTA M LG +T +Q+ +
Sbjct: 79 RVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVF 138
Query: 182 HFKDFVNASSKYEITTIHNLFRKLTHRLFRR-NFGYTLRSVNDLYIQKQFPILLDFKTKV 240
F +S IH F KL RL+R+ N L S N L+ K ++
Sbjct: 139 KFDTISEKTS----DQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDIS 194
Query: 241 REYYFAEAQIADFSDPAFISKT--NNHIMKLTKGLIKDAL--ENIDPATQMMILNCIYFK 296
Y A+ Q DF + A S+ N + T+G I D + E I+ T ++++N IYFK
Sbjct: 195 ELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFK 254
Query: 297 GSWVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVG-GISM 355
G W +KF E T F + E SMM +G F E +L+L + G I+M
Sbjct: 255 GLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELPFKGDDITM 313
Query: 356 LIVVPHKMSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIR 415
++++P + +E +LTP V++ W + V +P+F++E ++L E L+ MG+
Sbjct: 314 VLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLV 373
Query: 416 MLFDKN-----GNMAGISDQRIAIDLFKHQGTITVNEEGTQA---TTVTTVGFMPLSTQV 467
LF G +A D D F H+ + VNEEG++A T V G +V
Sbjct: 374 DLFSPEKSKLPGIVAEGRDDLYVSDAF-HKAFLEVNEEGSEAAASTAVVIAGRSLNPNRV 432
Query: 468 RFTVDRPFLFLIYEHRTSCLLFMGRVANP 496
F +RPFL I E + ++FMGRVANP
Sbjct: 433 TFKANRPFLVFIREVPLNTIIFMGRVANP 461
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,821,946
Number of Sequences: 37866
Number of extensions: 693161
Number of successful extensions: 2287
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1997
Number of HSP's gapped (non-prelim): 76
length of query: 499
length of database: 18,247,518
effective HSP length: 106
effective length of query: 393
effective length of database: 14,233,722
effective search space: 5593852746
effective search space used: 5593852746
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.