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Search of human proteins with 71834857
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71834857 prostate specific antigen isoform 5 preproprotein
[Homo sapiens]
(220 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71834857 prostate specific antigen isoform 5 preproprotein [H... 469 e-132
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 449 e-126
gi|71834855 prostate specific antigen isoform 4 preproprotein [H... 352 1e-97
gi|71834853 prostate specific antigen isoform 3 preproprotein [H... 339 1e-93
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 339 1e-93
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 249 1e-66
gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens] 237 7e-63
gi|11496281 kallikrein 13 precursor [Homo sapiens] 189 2e-48
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 172 3e-43
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 172 3e-43
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 172 3e-43
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 171 6e-43
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 171 6e-43
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 171 6e-43
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 166 2e-41
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 164 4e-41
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 161 4e-40
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 160 6e-40
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 159 2e-39
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 158 3e-39
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 155 2e-38
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 155 3e-38
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 155 3e-38
gi|71834859 prostate specific antigen isoform 6 preproprotein [H... 148 3e-36
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 148 3e-36
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 148 3e-36
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 147 7e-36
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 147 7e-36
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 147 7e-36
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 140 8e-34
>gi|71834857 prostate specific antigen isoform 5 preproprotein [Homo
sapiens]
Length = 220
Score = 469 bits (1206), Expect = e-132
Identities = 220/220 (100%), Positives = 220/220 (100%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSIE 120
LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSIE
Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSIE 120
Query: 121 PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG 180
PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG
Sbjct: 121 PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG 180
Query: 181 VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 220
VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP
Sbjct: 181 VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 220
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 449 bits (1154), Expect = e-126
Identities = 220/261 (84%), Positives = 220/261 (84%), Gaps = 41/261 (15%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS--- 117
LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS
Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
Query: 118 --------------------------------------SIEPEEFLTPKKLQCVDLHVIS 139
SIEPEEFLTPKKLQCVDLHVIS
Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180
Query: 140 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 199
NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP
Sbjct: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 240
Query: 200 SLYTKVVHYRKWIKDTIVANP 220
SLYTKVVHYRKWIKDTIVANP
Sbjct: 241 SLYTKVVHYRKWIKDTIVANP 261
>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
sapiens]
Length = 218
Score = 352 bits (904), Expect = 1e-97
Identities = 174/220 (79%), Positives = 180/220 (81%), Gaps = 2/220 (0%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSIE 120
LTAAHCIR L + ++ P + +L + SIE
Sbjct: 61 LTAAHCIRKPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGW--GSIE 118
Query: 121 PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG 180
PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG
Sbjct: 119 PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG 178
Query: 181 VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 220
VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP
Sbjct: 179 VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 218
>gi|71834853 prostate specific antigen isoform 3 preproprotein [Homo
sapiens]
Length = 238
Score = 339 bits (870), Expect = 1e-93
Identities = 169/210 (80%), Positives = 169/210 (80%), Gaps = 41/210 (19%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS--- 117
LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS
Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
Query: 118 --------------------------------------SIEPEEFLTPKKLQCVDLHVIS 139
SIEPEEFLTPKKLQCVDLHVIS
Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180
Query: 140 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCS 169
NDVCAQVHPQKVTKFMLCAGRWTGGKSTCS
Sbjct: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCS 210
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 339 bits (870), Expect = 1e-93
Identities = 165/261 (63%), Positives = 186/261 (71%), Gaps = 41/261 (15%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MW V+ + LSV GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV
Sbjct: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSS-- 118
LTAAHC++ S + LGRH+LF PEDTGQ VSHSFPHPLY+MSLLK++ LRP +DSS
Sbjct: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
Query: 119 ---------------------------------------IEPEEFLTPKKLQCVDLHVIS 139
IEPEEFL P+ LQCV LH++S
Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
Query: 140 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 199
ND+CA+ + +KVT+FMLCAG WTGGK TC GDSGGPLVCNGVLQGITSWG EPCALPE+P
Sbjct: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 240
Query: 200 SLYTKVVHYRKWIKDTIVANP 220
++YTKVVHYRKWIKDTI ANP
Sbjct: 241 AVYTKVVHYRKWIKDTIAANP 261
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 249 bits (637), Expect = 1e-66
Identities = 129/261 (49%), Positives = 152/261 (58%), Gaps = 42/261 (16%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MW V+ L LS+ GAAP I SRIVGGWECE+HSQPWQ + CGG+LVH QWV
Sbjct: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKN------------ 108
LTAAHCI + + LGRH+LF E+T Q VS SFPHP ++MSLL+N
Sbjct: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
Query: 109 ----RFLRPGDD--------------------------SSIEPEEFLTPKKLQCVDLHVI 138
R P D SIEPE F P LQCVDL ++
Sbjct: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
Query: 139 SNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPER 198
ND C + H QKVT FMLC G GGK TC GDSGGPL+C+GVLQG+TSWG PC P +
Sbjct: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240
Query: 199 PSLYTKVVHYRKWIKDTIVAN 219
PS+ +V+ Y KWI+DTI N
Sbjct: 241 PSVAVRVLSYVKWIEDTIAEN 261
>gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens]
Length = 223
Score = 237 bits (604), Expect = 7e-63
Identities = 119/209 (56%), Positives = 137/209 (65%), Gaps = 41/209 (19%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MW V+ + LSV GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV
Sbjct: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS--- 117
LTAAHC++ S + LGRH+LF PEDTGQ VSHSFPHPLY+MSLLK++ LRP +DS
Sbjct: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
Query: 118 --------------------------------------SIEPEEFLTPKKLQCVDLHVIS 139
SIEPEEFL P+ LQCV LH++S
Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
Query: 140 NDVCAQVHPQKVTKFMLCAGRWTGGKSTC 168
ND+CA+ + +KVT+FMLCAG WTGGK TC
Sbjct: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTC 209
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 189 bits (479), Expect = 2e-48
Identities = 99/225 (44%), Positives = 126/225 (56%), Gaps = 35/225 (15%)
Query: 27 GGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDT 86
GG+ C HSQPWQ + +GR +CGGVLVHP+WVLTAAHC++ + LG+H+L E
Sbjct: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
Query: 87 GQVFQVSHSFPHPLY-----------DMSLLK------------------NRFLRPGDDS 117
QV +V HS PHP Y D+ LL+ N L PG
Sbjct: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
Query: 118 SIEPEEFLT------PKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGD 171
+ T PK LQC ++ + S++ C QV+P K+T MLCAG GGK +C GD
Sbjct: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
Query: 172 SGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 216
SGGPLVCN L GI SWG PC P+RP +YT+V Y WI++TI
Sbjct: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 172 bits (435), Expect = 3e-43
Identities = 93/229 (40%), Positives = 129/229 (56%), Gaps = 33/229 (14%)
Query: 23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81
SRI+ G +C+ H+QPWQ + R + CG VLVHPQW+LTAAHC + + LG +SL
Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
Query: 82 HPEDTGQ-VFQVSHSFPHPLY-------DMSLLK-NRFLRPGDD---------------- 116
++GQ +FQ S PHP Y D+ L+K NR +RP D
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTK 184
Query: 117 ------SSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSG 170
+ + + PK LQC+++ V+S C +P+++ M CAG G+ +C G
Sbjct: 185 CLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDSCQG 243
Query: 171 DSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 219
DSGGP+VCNG LQG+ SWG PCA P RP +YT + + KWI++TI AN
Sbjct: 244 DSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 172 bits (435), Expect = 3e-43
Identities = 93/229 (40%), Positives = 129/229 (56%), Gaps = 33/229 (14%)
Query: 23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81
SRI+ G +C+ H+QPWQ + R + CG VLVHPQW+LTAAHC + + LG +SL
Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
Query: 82 HPEDTGQ-VFQVSHSFPHPLY-------DMSLLK-NRFLRPGDD---------------- 116
++GQ +FQ S PHP Y D+ L+K NR +RP D
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTK 184
Query: 117 ------SSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSG 170
+ + + PK LQC+++ V+S C +P+++ M CAG G+ +C G
Sbjct: 185 CLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDSCQG 243
Query: 171 DSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 219
DSGGP+VCNG LQG+ SWG PCA P RP +YT + + KWI++TI AN
Sbjct: 244 DSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 172 bits (435), Expect = 3e-43
Identities = 93/229 (40%), Positives = 129/229 (56%), Gaps = 33/229 (14%)
Query: 23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81
SRI+ G +C+ H+QPWQ + R + CG VLVHPQW+LTAAHC + + LG +SL
Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
Query: 82 HPEDTGQ-VFQVSHSFPHPLY-------DMSLLK-NRFLRPGDD---------------- 116
++GQ +FQ S PHP Y D+ L+K NR +RP D
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTK 184
Query: 117 ------SSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSG 170
+ + + PK LQC+++ V+S C +P+++ M CAG G+ +C G
Sbjct: 185 CLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDSCQG 243
Query: 171 DSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 219
DSGGP+VCNG LQG+ SWG PCA P RP +YT + + KWI++TI AN
Sbjct: 244 DSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 171 bits (432), Expect = 6e-43
Identities = 87/249 (34%), Positives = 130/249 (52%), Gaps = 38/249 (15%)
Query: 5 VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA 64
++ L L+ +G +RI+ G+EC+ HSQPWQ + + R +CG L+ P+W+LTAA
Sbjct: 6 LILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61
Query: 65 HCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSL------------------- 105
HC++ + ++ LG+H+L E Q + SFPHP ++ SL
Sbjct: 62 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 121
Query: 106 ---------LKNRFLRPGDD------SSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK 150
L +R + G S + P L+C ++ +I + C +P
Sbjct: 122 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 181
Query: 151 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRK 210
+T M+CA GGK +C GDSGGPLVCN LQGI SWG +PCA+ +P +YTKV Y
Sbjct: 182 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 241
Query: 211 WIKDTIVAN 219
WI++T+ N
Sbjct: 242 WIQETMKNN 250
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 171 bits (432), Expect = 6e-43
Identities = 87/249 (34%), Positives = 130/249 (52%), Gaps = 38/249 (15%)
Query: 5 VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA 64
++ L L+ +G +RI+ G+EC+ HSQPWQ + + R +CG L+ P+W+LTAA
Sbjct: 38 LILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93
Query: 65 HCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSL------------------- 105
HC++ + ++ LG+H+L E Q + SFPHP ++ SL
Sbjct: 94 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 153
Query: 106 ---------LKNRFLRPGDD------SSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK 150
L +R + G S + P L+C ++ +I + C +P
Sbjct: 154 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 213
Query: 151 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRK 210
+T M+CA GGK +C GDSGGPLVCN LQGI SWG +PCA+ +P +YTKV Y
Sbjct: 214 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 273
Query: 211 WIKDTIVAN 219
WI++T+ N
Sbjct: 274 WIQETMKNN 282
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 171 bits (432), Expect = 6e-43
Identities = 87/249 (34%), Positives = 130/249 (52%), Gaps = 38/249 (15%)
Query: 5 VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA 64
++ L L+ +G +RI+ G+EC+ HSQPWQ + + R +CG L+ P+W+LTAA
Sbjct: 6 LILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61
Query: 65 HCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSL------------------- 105
HC++ + ++ LG+H+L E Q + SFPHP ++ SL
Sbjct: 62 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 121
Query: 106 ---------LKNRFLRPGDD------SSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK 150
L +R + G S + P L+C ++ +I + C +P
Sbjct: 122 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 181
Query: 151 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRK 210
+T M+CA GGK +C GDSGGPLVCN LQGI SWG +PCA+ +P +YTKV Y
Sbjct: 182 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 241
Query: 211 WIKDTIVAN 219
WI++T+ N
Sbjct: 242 WIQETMKNN 250
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 166 bits (419), Expect = 2e-41
Identities = 96/250 (38%), Positives = 135/250 (54%), Gaps = 37/250 (14%)
Query: 4 PVVFLTLSVTWIGAAPLILS-----RIVGGWECEKHSQPWQ--VLVASRGRAVCGGVLVH 56
P +FL L+ + A + S +I+GG C + SQPWQ +L R R +CGG L+
Sbjct: 15 PKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLS 74
Query: 57 PQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLY-------DMSLLK-- 107
QWV+TAAHC R + LG+H+L E T QV +V HP Y D+ LL+
Sbjct: 75 GQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQ 134
Query: 108 -----NRFLRPGDDS----------------SIEPEEFLTPKKLQCVDLHVISNDVCAQV 146
R +RP + + +I P LQCV++++ ++VC +
Sbjct: 135 QPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKA 194
Query: 147 HPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVV 206
+P+ +T M+CAG GGK +C GDSGGPLVC G LQG+ SWG E CALP P +YT +
Sbjct: 195 YPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLC 254
Query: 207 HYRKWIKDTI 216
YR WI++T+
Sbjct: 255 KYRSWIEETM 264
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 164 bits (416), Expect = 4e-41
Identities = 90/242 (37%), Positives = 122/242 (50%), Gaps = 34/242 (14%)
Query: 8 LTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI 67
L L W G + +++GG EC+ HSQPWQ + + +CGGVLV WVLTAAHC
Sbjct: 16 LLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK 75
Query: 68 RNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLY----------DMSLLKNR-------- 109
+ K + LG HSL + + Q V S PHP Y D+ LL+ R
Sbjct: 76 KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSK 135
Query: 110 ---------FLRPGDDSSIEPEEFLT------PKKLQCVDLHVISNDVCAQVHPQKVTKF 154
+PG ++ +T P L C ++ + C +P ++T
Sbjct: 136 VKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDG 195
Query: 155 MLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 214
M+CAG + G TC GDSGGPLVC+G LQGITSWGS+PC ++P +YT + Y WIK
Sbjct: 196 MVCAGS-SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 254
Query: 215 TI 216
I
Sbjct: 255 II 256
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 161 bits (408), Expect = 4e-40
Identities = 81/226 (35%), Positives = 117/226 (51%), Gaps = 34/226 (15%)
Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82
+R +G EC +SQPWQ + R CG L+ +W+LTAAHC + + LG H L+
Sbjct: 21 TRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEHHLWK 80
Query: 83 PEDTGQVFQVSHSFPHPLYDMSL----------------------------LKNRFLRPG 114
E Q+F+V+ FPHP ++ L L + PG
Sbjct: 81 WEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQPLNLSQTCVSPG 140
Query: 115 DD------SSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTC 168
++ + L P LQC ++ ++ N +C +P ++ MLCAG W GG+ +C
Sbjct: 141 MQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLWEGGRGSC 200
Query: 169 SGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 214
GDSGGPLVCNG L G+ S G+EPC+ P RP++YT V HY WI++
Sbjct: 201 QGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQE 246
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 160 bits (406), Expect = 6e-40
Identities = 86/226 (38%), Positives = 117/226 (51%), Gaps = 34/226 (15%)
Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83
+++GG EC+ HSQPWQ + + +CGGVLV WVLTAAHC + K + LG HSL +
Sbjct: 77 KVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNK 136
Query: 84 EDTGQVFQVSHSFPHPLY----------DMSLLKNR-----------------FLRPGDD 116
+ Q V S PHP Y D+ LL+ R +PG
Sbjct: 137 DGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQK 196
Query: 117 SSIEPEEFLT------PKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSG 170
++ +T P L C ++ + C +P ++T M+CAG + G TC G
Sbjct: 197 CTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS-SKGADTCQG 255
Query: 171 DSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 216
DSGGPLVC+G LQGITSWGS+PC ++P +YT + Y WIK I
Sbjct: 256 DSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 159 bits (402), Expect = 2e-39
Identities = 91/259 (35%), Positives = 125/259 (48%), Gaps = 43/259 (16%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MW+ LTLS A +++ G EC HSQPWQV + RGR CG L+ P WV
Sbjct: 1 MWL---LLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWV 57
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDM----------------- 103
L+AAHC + LG H+L + Q+ S PHP Y+
Sbjct: 58 LSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPAR 117
Query: 104 -------SLLKNRFLRPGDDSSI---------EP-------EEFLTPKKLQCVDLHVISN 140
++L R PG+ + EP + P L C ++ +IS+
Sbjct: 118 LNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISD 177
Query: 141 DVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPS 200
C + +P ++T M+CAG G +C GDSGGPLVC G+LQGI SWG PC +P
Sbjct: 178 TSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPG 237
Query: 201 LYTKVVHYRKWIKDTIVAN 219
+YTKV HY +WI++T+ N
Sbjct: 238 VYTKVCHYLEWIRETMKRN 256
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 158 bits (400), Expect = 3e-39
Identities = 83/226 (36%), Positives = 118/226 (52%), Gaps = 29/226 (12%)
Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82
S+I+ G +C HSQPWQ + C GVLVHPQWVL+AAHC +N I LG HSL
Sbjct: 29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88
Query: 83 PEDTG-QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSIEPEEFLT--------------- 126
++ G Q+ + S S HP Y+ LL N + D S+ + +
Sbjct: 89 DQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSC 148
Query: 127 -------------PKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSG 173
P LQCV++ V+S +VC++++ M CAG K +C+GDSG
Sbjct: 149 LVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208
Query: 174 GPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 219
GPL+CNG LQG+ S+G PC P +YT + + +WI+ T+ A+
Sbjct: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 155 bits (393), Expect = 2e-38
Identities = 89/246 (36%), Positives = 126/246 (51%), Gaps = 32/246 (13%)
Query: 4 PVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTA 63
P++ LT + A +IVGG+ CE++S P+QV + S G CGG L++ QWV++A
Sbjct: 3 PLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNS-GYHFCGGSLINEQWVVSA 61
Query: 64 AHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFL------RPGDDS 117
HC +++ + LG H++ E Q + HP YD L N + R ++
Sbjct: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINA 121
Query: 118 SIEPEEFLT------------------------PKKLQCVDLHVISNDVCAQVHPQKVTK 153
+ T P +LQC+D V+S C +P K+T
Sbjct: 122 RVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITS 181
Query: 154 FMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 213
M C G GGK +C GDSGGP+VCNG LQG+ SWG + CA +P +YTKV +Y KWIK
Sbjct: 182 NMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIK 240
Query: 214 DTIVAN 219
+TI AN
Sbjct: 241 NTIAAN 246
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 155 bits (392), Expect = 3e-38
Identities = 80/224 (35%), Positives = 117/224 (52%), Gaps = 28/224 (12%)
Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82
+++V G C+K S P+Q + + G +CGGVL+HP WVLTAAHC + + LG+H+L
Sbjct: 20 NKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQ 79
Query: 83 PEDTGQVFQVSHSFPHPLY-----DMSLLKNRFLRPGDDSSI------------------ 119
E + + V + HP Y D ++ R RP S +
Sbjct: 80 RESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCH 139
Query: 120 -----EPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGG 174
+ + P +QC +H++S + C +P ++T+ MLCAG GK +C GDSGG
Sbjct: 140 ILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGG 199
Query: 175 PLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 218
PLVC L+G+ SWG+ PC E+P +YT V Y WI+ TI A
Sbjct: 200 PLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 155 bits (392), Expect = 3e-38
Identities = 80/224 (35%), Positives = 117/224 (52%), Gaps = 28/224 (12%)
Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82
+++V G C+K S P+Q + + G +CGGVL+HP WVLTAAHC + + LG+H+L
Sbjct: 20 NKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQ 79
Query: 83 PEDTGQVFQVSHSFPHPLY-----DMSLLKNRFLRPGDDSSI------------------ 119
E + + V + HP Y D ++ R RP S +
Sbjct: 80 RESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCH 139
Query: 120 -----EPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGG 174
+ + P +QC +H++S + C +P ++T+ MLCAG GK +C GDSGG
Sbjct: 140 ILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGG 199
Query: 175 PLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 218
PLVC L+G+ SWG+ PC E+P +YT V Y WI+ TI A
Sbjct: 200 PLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243
>gi|71834859 prostate specific antigen isoform 6 preproprotein
[Homo sapiens]
Length = 69
Score = 148 bits (374), Expect = 3e-36
Identities = 68/68 (100%), Positives = 68/68 (100%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCIR 68
LTAAHCIR
Sbjct: 61 LTAAHCIR 68
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 148 bits (374), Expect = 3e-36
Identities = 91/246 (36%), Positives = 123/246 (50%), Gaps = 36/246 (14%)
Query: 8 LTLSVTWIGAAPLIL----SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTA 63
L L +T++ AA +IVGG+ CE++S P+QV + S G CGG L+ QWV++A
Sbjct: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNS-GYHFCGGSLISEQWVVSA 61
Query: 64 AHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLR----------- 112
HC +++ + LG H++ E Q + HP Y+ L N L
Sbjct: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINS 121
Query: 113 -------PGDDSSIEPEEFLT------------PKKLQCVDLHVISNDVCAQVHPQKVTK 153
P + E ++ P +LQC+D V+S C +P K+T
Sbjct: 122 RVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITN 181
Query: 154 FMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 213
M C G GGK +C GDSGGP+V NG LQGI SWG CA RP +YTKV +Y WIK
Sbjct: 182 NMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIK 240
Query: 214 DTIVAN 219
DTI AN
Sbjct: 241 DTIAAN 246
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 148 bits (374), Expect = 3e-36
Identities = 87/244 (35%), Positives = 123/244 (50%), Gaps = 36/244 (14%)
Query: 10 LSVTWIGAAPLIL----SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65
L + ++GAA + +IVGG+ CE++S P+QV + S G CGG L+ QWV++AAH
Sbjct: 5 LILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAH 63
Query: 66 CIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLR------------- 112
C + + + LG H++ E Q + HP Y+ L N +
Sbjct: 64 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV 123
Query: 113 -----PGDDSSIEPEEFLT------------PKKLQCVDLHVISNDVCAQVHPQKVTKFM 155
P + E ++ P +L+C+D V++ C +P K+T M
Sbjct: 124 STISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSM 183
Query: 156 LCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 215
C G GGK +C DSGGP+VCNG LQG+ SWG CA RP +YTKV +Y WIKDT
Sbjct: 184 FCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDT 242
Query: 216 IVAN 219
I AN
Sbjct: 243 IAAN 246
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 147 bits (371), Expect = 7e-36
Identities = 84/223 (37%), Positives = 115/223 (51%), Gaps = 32/223 (14%)
Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83
+I+ G C + S PWQV + S + CGGVLV+ +WVLTAAHC N+ + LG +L
Sbjct: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--G 86
Query: 84 EDTGQVFQVSHSFPHPLY-------DMSLLK-----------------NRFLRPGDDSSI 119
+ Q + S SF HP Y D+ L+K +R PG ++
Sbjct: 87 DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146
Query: 120 E------PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSG 173
+ P L CVD+ +IS C +V+ + MLCAG K+ C+GDSG
Sbjct: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSG 206
Query: 174 GPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 216
GPLVC G LQG+ SWG+ PC P P +YT+V + KWI DT+
Sbjct: 207 GPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 147 bits (371), Expect = 7e-36
Identities = 84/223 (37%), Positives = 115/223 (51%), Gaps = 32/223 (14%)
Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83
+I+ G C + S PWQV + S + CGGVLV+ +WVLTAAHC N+ + LG +L
Sbjct: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--G 86
Query: 84 EDTGQVFQVSHSFPHPLY-------DMSLLK-----------------NRFLRPGDDSSI 119
+ Q + S SF HP Y D+ L+K +R PG ++
Sbjct: 87 DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146
Query: 120 E------PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSG 173
+ P L CVD+ +IS C +V+ + MLCAG K+ C+GDSG
Sbjct: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSG 206
Query: 174 GPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 216
GPLVC G LQG+ SWG+ PC P P +YT+V + KWI DT+
Sbjct: 207 GPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 147 bits (371), Expect = 7e-36
Identities = 83/226 (36%), Positives = 115/226 (50%), Gaps = 32/226 (14%)
Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83
+IVGG+ CE++S P+QV + S G CGG L+ QWV++AAHC + + + LG H++
Sbjct: 80 KIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVL 138
Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLR------------------PGDDSSIEPEEFL 125
E Q + HP Y+ L N + P + E +
Sbjct: 139 EGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECLI 198
Query: 126 T------------PKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSG 173
+ P +L+C+D V++ C +P K+T M C G GGK +C DSG
Sbjct: 199 SGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSG 258
Query: 174 GPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 219
GP+VCNG LQG+ SWG CA RP +YTKV +Y WIKDTI AN
Sbjct: 259 GPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 303
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 140 bits (353), Expect = 8e-34
Identities = 89/242 (36%), Positives = 121/242 (50%), Gaps = 38/242 (15%)
Query: 6 VFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65
+FL L V +G + +I G EC ++SQPWQV + CGGVL+ +WVLTAAH
Sbjct: 5 IFLLLCV--LGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
Query: 66 CIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLY---------DMSLLKNRFLRPGDD 116
C ++ + LG HSL + T Q+ S HP Y D+ LL+ R L
Sbjct: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLR-LPVRVT 121
Query: 117 SSIEPEEFLT------------------------PKKLQCVDLHVISNDVCAQVHPQKVT 152
SS++P P LQC++L ++S+ C V+P ++T
Sbjct: 122 SSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRIT 181
Query: 153 KFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGS-EPCALPERPSLYTKVVHYRKW 211
M+CAG G+ C GDSGGPLVC GVLQG+ SWGS PC P +YT + Y W
Sbjct: 182 SNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDW 240
Query: 212 IK 213
I+
Sbjct: 241 IR 242
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.464
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,889,856
Number of Sequences: 37866
Number of extensions: 462405
Number of successful extensions: 1378
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 866
Number of HSP's gapped (non-prelim): 307
length of query: 220
length of database: 18,247,518
effective HSP length: 98
effective length of query: 122
effective length of database: 14,536,650
effective search space: 1773471300
effective search space used: 1773471300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.