BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|71834857 prostate specific antigen isoform 5 preproprotein [Homo sapiens] (220 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|71834857 prostate specific antigen isoform 5 preproprotein [H... 469 e-132 gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 449 e-126 gi|71834855 prostate specific antigen isoform 4 preproprotein [H... 352 1e-97 gi|71834853 prostate specific antigen isoform 3 preproprotein [H... 339 1e-93 gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 339 1e-93 gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 249 1e-66 gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens] 237 7e-63 gi|11496281 kallikrein 13 precursor [Homo sapiens] 189 2e-48 gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 172 3e-43 gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 172 3e-43 gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 172 3e-43 gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 171 6e-43 gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 171 6e-43 gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 171 6e-43 gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 166 2e-41 gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 164 4e-41 gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 161 4e-40 gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 160 6e-40 gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 159 2e-39 gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 158 3e-39 gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 155 2e-38 gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 155 3e-38 gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 155 3e-38 gi|71834859 prostate specific antigen isoform 6 preproprotein [H... 148 3e-36 gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 148 3e-36 gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 148 3e-36 gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 147 7e-36 gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 147 7e-36 gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 147 7e-36 gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 140 8e-34 >gi|71834857 prostate specific antigen isoform 5 preproprotein [Homo sapiens] Length = 220 Score = 469 bits (1206), Expect = e-132 Identities = 220/220 (100%), Positives = 220/220 (100%) Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSIE 120 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSIE Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSIE 120 Query: 121 PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG 180 PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG Sbjct: 121 PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG 180 Query: 181 VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 220 VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP Sbjct: 181 VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 220 >gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo sapiens] Length = 261 Score = 449 bits (1154), Expect = e-126 Identities = 220/261 (84%), Positives = 220/261 (84%), Gaps = 41/261 (15%) Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS--- 117 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120 Query: 118 --------------------------------------SIEPEEFLTPKKLQCVDLHVIS 139 SIEPEEFLTPKKLQCVDLHVIS Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180 Query: 140 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 199 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP Sbjct: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 240 Query: 200 SLYTKVVHYRKWIKDTIVANP 220 SLYTKVVHYRKWIKDTIVANP Sbjct: 241 SLYTKVVHYRKWIKDTIVANP 261 >gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo sapiens] Length = 218 Score = 352 bits (904), Expect = 1e-97 Identities = 174/220 (79%), Positives = 180/220 (81%), Gaps = 2/220 (0%) Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSIE 120 LTAAHCIR L + ++ P + +L + SIE Sbjct: 61 LTAAHCIRKPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGW--GSIE 118 Query: 121 PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG 180 PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG Sbjct: 119 PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG 178 Query: 181 VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 220 VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP Sbjct: 179 VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 218 >gi|71834853 prostate specific antigen isoform 3 preproprotein [Homo sapiens] Length = 238 Score = 339 bits (870), Expect = 1e-93 Identities = 169/210 (80%), Positives = 169/210 (80%), Gaps = 41/210 (19%) Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS--- 117 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120 Query: 118 --------------------------------------SIEPEEFLTPKKLQCVDLHVIS 139 SIEPEEFLTPKKLQCVDLHVIS Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180 Query: 140 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCS 169 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCS Sbjct: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCS 210 >gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] Length = 261 Score = 339 bits (870), Expect = 1e-93 Identities = 165/261 (63%), Positives = 186/261 (71%), Gaps = 41/261 (15%) Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 MW V+ + LSV GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV Sbjct: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60 Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSS-- 118 LTAAHC++ S + LGRH+LF PEDTGQ VSHSFPHPLY+MSLLK++ LRP +DSS Sbjct: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120 Query: 119 ---------------------------------------IEPEEFLTPKKLQCVDLHVIS 139 IEPEEFL P+ LQCV LH++S Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180 Query: 140 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 199 ND+CA+ + +KVT+FMLCAG WTGGK TC GDSGGPLVCNGVLQGITSWG EPCALPE+P Sbjct: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 240 Query: 200 SLYTKVVHYRKWIKDTIVANP 220 ++YTKVVHYRKWIKDTI ANP Sbjct: 241 AVYTKVVHYRKWIKDTIAANP 261 >gi|4504875 kallikrein 1 preproprotein [Homo sapiens] Length = 262 Score = 249 bits (637), Expect = 1e-66 Identities = 129/261 (49%), Positives = 152/261 (58%), Gaps = 42/261 (16%) Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 MW V+ L LS+ GAAP I SRIVGGWECE+HSQPWQ + CGG+LVH QWV Sbjct: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60 Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKN------------ 108 LTAAHCI + + LGRH+LF E+T Q VS SFPHP ++MSLL+N Sbjct: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120 Query: 109 ----RFLRPGDD--------------------------SSIEPEEFLTPKKLQCVDLHVI 138 R P D SIEPE F P LQCVDL ++ Sbjct: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180 Query: 139 SNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPER 198 ND C + H QKVT FMLC G GGK TC GDSGGPL+C+GVLQG+TSWG PC P + Sbjct: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240 Query: 199 PSLYTKVVHYRKWIKDTIVAN 219 PS+ +V+ Y KWI+DTI N Sbjct: 241 PSVAVRVLSYVKWIEDTIAEN 261 >gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens] Length = 223 Score = 237 bits (604), Expect = 7e-63 Identities = 119/209 (56%), Positives = 137/209 (65%), Gaps = 41/209 (19%) Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 MW V+ + LSV GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV Sbjct: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60 Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS--- 117 LTAAHC++ S + LGRH+LF PEDTGQ VSHSFPHPLY+MSLLK++ LRP +DS Sbjct: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120 Query: 118 --------------------------------------SIEPEEFLTPKKLQCVDLHVIS 139 SIEPEEFL P+ LQCV LH++S Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180 Query: 140 NDVCAQVHPQKVTKFMLCAGRWTGGKSTC 168 ND+CA+ + +KVT+FMLCAG WTGGK TC Sbjct: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTC 209 >gi|11496281 kallikrein 13 precursor [Homo sapiens] Length = 277 Score = 189 bits (479), Expect = 2e-48 Identities = 99/225 (44%), Positives = 126/225 (56%), Gaps = 35/225 (15%) Query: 27 GGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDT 86 GG+ C HSQPWQ + +GR +CGGVLVHP+WVLTAAHC++ + LG+H+L E Sbjct: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97 Query: 87 GQVFQVSHSFPHPLY-----------DMSLLK------------------NRFLRPGDDS 117 QV +V HS PHP Y D+ LL+ N L PG Sbjct: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157 Query: 118 SIEPEEFLT------PKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGD 171 + T PK LQC ++ + S++ C QV+P K+T MLCAG GGK +C GD Sbjct: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217 Query: 172 SGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 216 SGGPLVCN L GI SWG PC P+RP +YT+V Y WI++TI Sbjct: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262 >gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo sapiens] Length = 293 Score = 172 bits (435), Expect = 3e-43 Identities = 93/229 (40%), Positives = 129/229 (56%), Gaps = 33/229 (14%) Query: 23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 SRI+ G +C+ H+QPWQ + R + CG VLVHPQW+LTAAHC + + LG +SL Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124 Query: 82 HPEDTGQ-VFQVSHSFPHPLY-------DMSLLK-NRFLRPGDD---------------- 116 ++GQ +FQ S PHP Y D+ L+K NR +RP D Sbjct: 125 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTK 184 Query: 117 ------SSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSG 170 + + + PK LQC+++ V+S C +P+++ M CAG G+ +C G Sbjct: 185 CLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDSCQG 243 Query: 171 DSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 219 DSGGP+VCNG LQG+ SWG PCA P RP +YT + + KWI++TI AN Sbjct: 244 DSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292 >gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo sapiens] Length = 293 Score = 172 bits (435), Expect = 3e-43 Identities = 93/229 (40%), Positives = 129/229 (56%), Gaps = 33/229 (14%) Query: 23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 SRI+ G +C+ H+QPWQ + R + CG VLVHPQW+LTAAHC + + LG +SL Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124 Query: 82 HPEDTGQ-VFQVSHSFPHPLY-------DMSLLK-NRFLRPGDD---------------- 116 ++GQ +FQ S PHP Y D+ L+K NR +RP D Sbjct: 125 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTK 184 Query: 117 ------SSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSG 170 + + + PK LQC+++ V+S C +P+++ M CAG G+ +C G Sbjct: 185 CLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDSCQG 243 Query: 171 DSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 219 DSGGP+VCNG LQG+ SWG PCA P RP +YT + + KWI++TI AN Sbjct: 244 DSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292 >gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sapiens] Length = 293 Score = 172 bits (435), Expect = 3e-43 Identities = 93/229 (40%), Positives = 129/229 (56%), Gaps = 33/229 (14%) Query: 23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 SRI+ G +C+ H+QPWQ + R + CG VLVHPQW+LTAAHC + + LG +SL Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124 Query: 82 HPEDTGQ-VFQVSHSFPHPLY-------DMSLLK-NRFLRPGDD---------------- 116 ++GQ +FQ S PHP Y D+ L+K NR +RP D Sbjct: 125 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTK 184 Query: 117 ------SSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSG 170 + + + PK LQC+++ V+S C +P+++ M CAG G+ +C G Sbjct: 185 CLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDSCQG 243 Query: 171 DSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 219 DSGGP+VCNG LQG+ SWG PCA P RP +YT + + KWI++TI AN Sbjct: 244 DSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292 >gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] Length = 250 Score = 171 bits (432), Expect = 6e-43 Identities = 87/249 (34%), Positives = 130/249 (52%), Gaps = 38/249 (15%) Query: 5 VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA 64 ++ L L+ +G +RI+ G+EC+ HSQPWQ + + R +CG L+ P+W+LTAA Sbjct: 6 LILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61 Query: 65 HCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSL------------------- 105 HC++ + ++ LG+H+L E Q + SFPHP ++ SL Sbjct: 62 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 121 Query: 106 ---------LKNRFLRPGDD------SSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK 150 L +R + G S + P L+C ++ +I + C +P Sbjct: 122 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 181 Query: 151 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRK 210 +T M+CA GGK +C GDSGGPLVCN LQGI SWG +PCA+ +P +YTKV Y Sbjct: 182 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 241 Query: 211 WIKDTIVAN 219 WI++T+ N Sbjct: 242 WIQETMKNN 250 >gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] Length = 282 Score = 171 bits (432), Expect = 6e-43 Identities = 87/249 (34%), Positives = 130/249 (52%), Gaps = 38/249 (15%) Query: 5 VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA 64 ++ L L+ +G +RI+ G+EC+ HSQPWQ + + R +CG L+ P+W+LTAA Sbjct: 38 LILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93 Query: 65 HCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSL------------------- 105 HC++ + ++ LG+H+L E Q + SFPHP ++ SL Sbjct: 94 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 153 Query: 106 ---------LKNRFLRPGDD------SSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK 150 L +R + G S + P L+C ++ +I + C +P Sbjct: 154 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 213 Query: 151 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRK 210 +T M+CA GGK +C GDSGGPLVCN LQGI SWG +PCA+ +P +YTKV Y Sbjct: 214 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 273 Query: 211 WIKDTIVAN 219 WI++T+ N Sbjct: 274 WIQETMKNN 282 >gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] Length = 250 Score = 171 bits (432), Expect = 6e-43 Identities = 87/249 (34%), Positives = 130/249 (52%), Gaps = 38/249 (15%) Query: 5 VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA 64 ++ L L+ +G +RI+ G+EC+ HSQPWQ + + R +CG L+ P+W+LTAA Sbjct: 6 LILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61 Query: 65 HCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSL------------------- 105 HC++ + ++ LG+H+L E Q + SFPHP ++ SL Sbjct: 62 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 121 Query: 106 ---------LKNRFLRPGDD------SSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK 150 L +R + G S + P L+C ++ +I + C +P Sbjct: 122 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 181 Query: 151 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRK 210 +T M+CA GGK +C GDSGGPLVCN LQGI SWG +PCA+ +P +YTKV Y Sbjct: 182 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 241 Query: 211 WIKDTIVAN 219 WI++T+ N Sbjct: 242 WIQETMKNN 250 >gi|91823048 kallikrein 14 preproprotein [Homo sapiens] Length = 267 Score = 166 bits (419), Expect = 2e-41 Identities = 96/250 (38%), Positives = 135/250 (54%), Gaps = 37/250 (14%) Query: 4 PVVFLTLSVTWIGAAPLILS-----RIVGGWECEKHSQPWQ--VLVASRGRAVCGGVLVH 56 P +FL L+ + A + S +I+GG C + SQPWQ +L R R +CGG L+ Sbjct: 15 PKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLS 74 Query: 57 PQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLY-------DMSLLK-- 107 QWV+TAAHC R + LG+H+L E T QV +V HP Y D+ LL+ Sbjct: 75 GQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQ 134 Query: 108 -----NRFLRPGDDS----------------SIEPEEFLTPKKLQCVDLHVISNDVCAQV 146 R +RP + + +I P LQCV++++ ++VC + Sbjct: 135 QPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKA 194 Query: 147 HPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVV 206 +P+ +T M+CAG GGK +C GDSGGPLVC G LQG+ SWG E CALP P +YT + Sbjct: 195 YPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLC 254 Query: 207 HYRKWIKDTI 216 YR WI++T+ Sbjct: 255 KYRSWIEETM 264 >gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] Length = 260 Score = 164 bits (416), Expect = 4e-41 Identities = 90/242 (37%), Positives = 122/242 (50%), Gaps = 34/242 (14%) Query: 8 LTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI 67 L L W G + +++GG EC+ HSQPWQ + + +CGGVLV WVLTAAHC Sbjct: 16 LLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK 75 Query: 68 RNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLY----------DMSLLKNR-------- 109 + K + LG HSL + + Q V S PHP Y D+ LL+ R Sbjct: 76 KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSK 135 Query: 110 ---------FLRPGDDSSIEPEEFLT------PKKLQCVDLHVISNDVCAQVHPQKVTKF 154 +PG ++ +T P L C ++ + C +P ++T Sbjct: 136 VKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDG 195 Query: 155 MLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 214 M+CAG + G TC GDSGGPLVC+G LQGITSWGS+PC ++P +YT + Y WIK Sbjct: 196 MVCAGS-SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 254 Query: 215 TI 216 I Sbjct: 255 II 256 >gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] Length = 250 Score = 161 bits (408), Expect = 4e-40 Identities = 81/226 (35%), Positives = 117/226 (51%), Gaps = 34/226 (15%) Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 +R +G EC +SQPWQ + R CG L+ +W+LTAAHC + + LG H L+ Sbjct: 21 TRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEHHLWK 80 Query: 83 PEDTGQVFQVSHSFPHPLYDMSL----------------------------LKNRFLRPG 114 E Q+F+V+ FPHP ++ L L + PG Sbjct: 81 WEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQPLNLSQTCVSPG 140 Query: 115 DD------SSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTC 168 ++ + L P LQC ++ ++ N +C +P ++ MLCAG W GG+ +C Sbjct: 141 MQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLWEGGRGSC 200 Query: 169 SGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 214 GDSGGPLVCNG L G+ S G+EPC+ P RP++YT V HY WI++ Sbjct: 201 QGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQE 246 >gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] Length = 305 Score = 160 bits (406), Expect = 6e-40 Identities = 86/226 (38%), Positives = 117/226 (51%), Gaps = 34/226 (15%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83 +++GG EC+ HSQPWQ + + +CGGVLV WVLTAAHC + K + LG HSL + Sbjct: 77 KVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNK 136 Query: 84 EDTGQVFQVSHSFPHPLY----------DMSLLKNR-----------------FLRPGDD 116 + Q V S PHP Y D+ LL+ R +PG Sbjct: 137 DGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQK 196 Query: 117 SSIEPEEFLT------PKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSG 170 ++ +T P L C ++ + C +P ++T M+CAG + G TC G Sbjct: 197 CTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS-SKGADTCQG 255 Query: 171 DSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 216 DSGGPLVC+G LQGITSWGS+PC ++P +YT + Y WIK I Sbjct: 256 DSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301 >gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein [Homo sapiens] Length = 256 Score = 159 bits (402), Expect = 2e-39 Identities = 91/259 (35%), Positives = 125/259 (48%), Gaps = 43/259 (16%) Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 MW+ LTLS A +++ G EC HSQPWQV + RGR CG L+ P WV Sbjct: 1 MWL---LLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWV 57 Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDM----------------- 103 L+AAHC + LG H+L + Q+ S PHP Y+ Sbjct: 58 LSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPAR 117 Query: 104 -------SLLKNRFLRPGDDSSI---------EP-------EEFLTPKKLQCVDLHVISN 140 ++L R PG+ + EP + P L C ++ +IS+ Sbjct: 118 LNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISD 177 Query: 141 DVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPS 200 C + +P ++T M+CAG G +C GDSGGPLVC G+LQGI SWG PC +P Sbjct: 178 TSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPG 237 Query: 201 LYTKVVHYRKWIKDTIVAN 219 +YTKV HY +WI++T+ N Sbjct: 238 VYTKVCHYLEWIRETMKRN 256 >gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo sapiens] Length = 254 Score = 158 bits (400), Expect = 3e-39 Identities = 83/226 (36%), Positives = 118/226 (52%), Gaps = 29/226 (12%) Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 S+I+ G +C HSQPWQ + C GVLVHPQWVL+AAHC +N I LG HSL Sbjct: 29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88 Query: 83 PEDTG-QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSIEPEEFLT--------------- 126 ++ G Q+ + S S HP Y+ LL N + D S+ + + Sbjct: 89 DQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSC 148 Query: 127 -------------PKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSG 173 P LQCV++ V+S +VC++++ M CAG K +C+GDSG Sbjct: 149 LVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 Query: 174 GPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 219 GPL+CNG LQG+ S+G PC P +YT + + +WI+ T+ A+ Sbjct: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 >gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] Length = 247 Score = 155 bits (393), Expect = 2e-38 Identities = 89/246 (36%), Positives = 126/246 (51%), Gaps = 32/246 (13%) Query: 4 PVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTA 63 P++ LT + A +IVGG+ CE++S P+QV + S G CGG L++ QWV++A Sbjct: 3 PLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNS-GYHFCGGSLINEQWVVSA 61 Query: 64 AHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFL------RPGDDS 117 HC +++ + LG H++ E Q + HP YD L N + R ++ Sbjct: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINA 121 Query: 118 SIEPEEFLT------------------------PKKLQCVDLHVISNDVCAQVHPQKVTK 153 + T P +LQC+D V+S C +P K+T Sbjct: 122 RVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITS 181 Query: 154 FMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 213 M C G GGK +C GDSGGP+VCNG LQG+ SWG + CA +P +YTKV +Y KWIK Sbjct: 182 NMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIK 240 Query: 214 DTIVAN 219 +TI AN Sbjct: 241 NTIAAN 246 >gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein [Homo sapiens] Length = 244 Score = 155 bits (392), Expect = 3e-38 Identities = 80/224 (35%), Positives = 117/224 (52%), Gaps = 28/224 (12%) Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 +++V G C+K S P+Q + + G +CGGVL+HP WVLTAAHC + + LG+H+L Sbjct: 20 NKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQ 79 Query: 83 PEDTGQVFQVSHSFPHPLY-----DMSLLKNRFLRPGDDSSI------------------ 119 E + + V + HP Y D ++ R RP S + Sbjct: 80 RESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCH 139 Query: 120 -----EPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGG 174 + + P +QC +H++S + C +P ++T+ MLCAG GK +C GDSGG Sbjct: 140 ILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGG 199 Query: 175 PLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 218 PLVC L+G+ SWG+ PC E+P +YT V Y WI+ TI A Sbjct: 200 PLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243 >gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein [Homo sapiens] Length = 244 Score = 155 bits (392), Expect = 3e-38 Identities = 80/224 (35%), Positives = 117/224 (52%), Gaps = 28/224 (12%) Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 +++V G C+K S P+Q + + G +CGGVL+HP WVLTAAHC + + LG+H+L Sbjct: 20 NKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQ 79 Query: 83 PEDTGQVFQVSHSFPHPLY-----DMSLLKNRFLRPGDDSSI------------------ 119 E + + V + HP Y D ++ R RP S + Sbjct: 80 RESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCH 139 Query: 120 -----EPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGG 174 + + P +QC +H++S + C +P ++T+ MLCAG GK +C GDSGG Sbjct: 140 ILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGG 199 Query: 175 PLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 218 PLVC L+G+ SWG+ PC E+P +YT V Y WI+ TI A Sbjct: 200 PLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243 >gi|71834859 prostate specific antigen isoform 6 preproprotein [Homo sapiens] Length = 69 Score = 148 bits (374), Expect = 3e-36 Identities = 68/68 (100%), Positives = 68/68 (100%) Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 Query: 61 LTAAHCIR 68 LTAAHCIR Sbjct: 61 LTAAHCIR 68 >gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] Length = 247 Score = 148 bits (374), Expect = 3e-36 Identities = 91/246 (36%), Positives = 123/246 (50%), Gaps = 36/246 (14%) Query: 8 LTLSVTWIGAAPLIL----SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTA 63 L L +T++ AA +IVGG+ CE++S P+QV + S G CGG L+ QWV++A Sbjct: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNS-GYHFCGGSLISEQWVVSA 61 Query: 64 AHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLR----------- 112 HC +++ + LG H++ E Q + HP Y+ L N L Sbjct: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINS 121 Query: 113 -------PGDDSSIEPEEFLT------------PKKLQCVDLHVISNDVCAQVHPQKVTK 153 P + E ++ P +LQC+D V+S C +P K+T Sbjct: 122 RVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITN 181 Query: 154 FMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 213 M C G GGK +C GDSGGP+V NG LQGI SWG CA RP +YTKV +Y WIK Sbjct: 182 NMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIK 240 Query: 214 DTIVAN 219 DTI AN Sbjct: 241 DTIAAN 246 >gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] Length = 247 Score = 148 bits (374), Expect = 3e-36 Identities = 87/244 (35%), Positives = 123/244 (50%), Gaps = 36/244 (14%) Query: 10 LSVTWIGAAPLIL----SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65 L + ++GAA + +IVGG+ CE++S P+QV + S G CGG L+ QWV++AAH Sbjct: 5 LILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAH 63 Query: 66 CIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLR------------- 112 C + + + LG H++ E Q + HP Y+ L N + Sbjct: 64 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV 123 Query: 113 -----PGDDSSIEPEEFLT------------PKKLQCVDLHVISNDVCAQVHPQKVTKFM 155 P + E ++ P +L+C+D V++ C +P K+T M Sbjct: 124 STISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSM 183 Query: 156 LCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 215 C G GGK +C DSGGP+VCNG LQG+ SWG CA RP +YTKV +Y WIKDT Sbjct: 184 FCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDT 242 Query: 216 IVAN 219 I AN Sbjct: 243 IAAN 246 >gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo sapiens] Length = 253 Score = 147 bits (371), Expect = 7e-36 Identities = 84/223 (37%), Positives = 115/223 (51%), Gaps = 32/223 (14%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83 +I+ G C + S PWQV + S + CGGVLV+ +WVLTAAHC N+ + LG +L Sbjct: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--G 86 Query: 84 EDTGQVFQVSHSFPHPLY-------DMSLLK-----------------NRFLRPGDDSSI 119 + Q + S SF HP Y D+ L+K +R PG ++ Sbjct: 87 DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146 Query: 120 E------PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSG 173 + P L CVD+ +IS C +V+ + MLCAG K+ C+GDSG Sbjct: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSG 206 Query: 174 GPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 216 GPLVC G LQG+ SWG+ PC P P +YT+V + KWI DT+ Sbjct: 207 GPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 >gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo sapiens] Length = 253 Score = 147 bits (371), Expect = 7e-36 Identities = 84/223 (37%), Positives = 115/223 (51%), Gaps = 32/223 (14%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83 +I+ G C + S PWQV + S + CGGVLV+ +WVLTAAHC N+ + LG +L Sbjct: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--G 86 Query: 84 EDTGQVFQVSHSFPHPLY-------DMSLLK-----------------NRFLRPGDDSSI 119 + Q + S SF HP Y D+ L+K +R PG ++ Sbjct: 87 DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146 Query: 120 E------PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSG 173 + P L CVD+ +IS C +V+ + MLCAG K+ C+GDSG Sbjct: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSG 206 Query: 174 GPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 216 GPLVC G LQG+ SWG+ PC P P +YT+V + KWI DT+ Sbjct: 207 GPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 >gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] Length = 304 Score = 147 bits (371), Expect = 7e-36 Identities = 83/226 (36%), Positives = 115/226 (50%), Gaps = 32/226 (14%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83 +IVGG+ CE++S P+QV + S G CGG L+ QWV++AAHC + + + LG H++ Sbjct: 80 KIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVL 138 Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLR------------------PGDDSSIEPEEFL 125 E Q + HP Y+ L N + P + E + Sbjct: 139 EGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECLI 198 Query: 126 T------------PKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSG 173 + P +L+C+D V++ C +P K+T M C G GGK +C DSG Sbjct: 199 SGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSG 258 Query: 174 GPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 219 GP+VCNG LQG+ SWG CA RP +YTKV +Y WIKDTI AN Sbjct: 259 GPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 303 >gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] Length = 248 Score = 140 bits (353), Expect = 8e-34 Identities = 89/242 (36%), Positives = 121/242 (50%), Gaps = 38/242 (15%) Query: 6 VFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65 +FL L V +G + +I G EC ++SQPWQV + CGGVL+ +WVLTAAH Sbjct: 5 IFLLLCV--LGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62 Query: 66 CIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLY---------DMSLLKNRFLRPGDD 116 C ++ + LG HSL + T Q+ S HP Y D+ LL+ R L Sbjct: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLR-LPVRVT 121 Query: 117 SSIEPEEFLT------------------------PKKLQCVDLHVISNDVCAQVHPQKVT 152 SS++P P LQC++L ++S+ C V+P ++T Sbjct: 122 SSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRIT 181 Query: 153 KFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGS-EPCALPERPSLYTKVVHYRKW 211 M+CAG G+ C GDSGGPLVC GVLQG+ SWGS PC P +YT + Y W Sbjct: 182 SNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDW 240 Query: 212 IK 213 I+ Sbjct: 241 IR 242 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.138 0.464 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,889,856 Number of Sequences: 37866 Number of extensions: 462405 Number of successful extensions: 1378 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 166 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 866 Number of HSP's gapped (non-prelim): 307 length of query: 220 length of database: 18,247,518 effective HSP length: 98 effective length of query: 122 effective length of database: 14,536,650 effective search space: 1773471300 effective search space used: 1773471300 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.