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Search of human proteins with 71834855
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71834855 prostate specific antigen isoform 4 preproprotein
[Homo sapiens]
(218 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71834855 prostate specific antigen isoform 4 preproprotein [H... 464 e-131
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 442 e-124
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 355 1e-98
gi|71834857 prostate specific antigen isoform 5 preproprotein [H... 352 1e-97
gi|71834853 prostate specific antigen isoform 3 preproprotein [H... 332 1e-91
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 274 5e-74
gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens] 253 9e-68
gi|11496281 kallikrein 13 precursor [Homo sapiens] 192 2e-49
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 183 1e-46
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 183 1e-46
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 183 1e-46
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 180 1e-45
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 180 1e-45
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 180 1e-45
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 178 4e-45
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 177 8e-45
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 175 3e-44
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 174 7e-44
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 172 2e-43
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 172 2e-43
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 171 4e-43
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 171 6e-43
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 171 6e-43
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 170 8e-43
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 170 8e-43
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 168 4e-42
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 167 6e-42
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 162 2e-40
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 157 5e-39
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 150 6e-37
>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
sapiens]
Length = 218
Score = 464 bits (1193), Expect = e-131
Identities = 218/218 (100%), Positives = 218/218 (100%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCIRKPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPE 120
LTAAHCIRKPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPE
Sbjct: 61 LTAAHCIRKPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPE 120
Query: 121 EFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVL 180
EFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVL
Sbjct: 121 EFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVL 180
Query: 181 QGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 218
QGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP
Sbjct: 181 QGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 218
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 442 bits (1136), Expect = e-124
Identities = 217/261 (83%), Positives = 218/261 (83%), Gaps = 43/261 (16%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCIR-------------------------------------------KPGDDSSHD 77
LTAAHCIR +PGDDSSHD
Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
Query: 78 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 137
LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS
Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180
Query: 138 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 197
NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP
Sbjct: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 240
Query: 198 SLYTKVVHYRKWIKDTIVANP 218
SLYTKVVHYRKWIKDTIVANP
Sbjct: 241 SLYTKVVHYRKWIKDTIVANP 261
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 355 bits (912), Expect = 1e-98
Identities = 172/261 (65%), Positives = 191/261 (73%), Gaps = 43/261 (16%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MW V+ + LSV GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV
Sbjct: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
Query: 61 LTAAHCIRK-------------------------------------------PGDDSSHD 77
LTAAHC++K P +DSSHD
Sbjct: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
Query: 78 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 137
LMLLRLSEPA++TD VKV+ LPTQEPALGTTCYASGWGSIEPEEFL P+ LQCV LH++S
Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
Query: 138 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 197
ND+CA+ + +KVT+FMLCAG WTGGK TC GDSGGPLVCNGVLQGITSWG EPCALPE+P
Sbjct: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 240
Query: 198 SLYTKVVHYRKWIKDTIVANP 218
++YTKVVHYRKWIKDTI ANP
Sbjct: 241 AVYTKVVHYRKWIKDTIAANP 261
>gi|71834857 prostate specific antigen isoform 5 preproprotein [Homo
sapiens]
Length = 220
Score = 352 bits (904), Expect = 1e-97
Identities = 174/220 (79%), Positives = 180/220 (81%), Gaps = 2/220 (0%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCIRKPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGW--GSIE 118
LTAAHCIR L + ++ P + +L + SIE
Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSIE 120
Query: 119 PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG 178
PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG
Sbjct: 121 PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG 180
Query: 179 VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 218
VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP
Sbjct: 181 VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 220
>gi|71834853 prostate specific antigen isoform 3 preproprotein [Homo
sapiens]
Length = 238
Score = 332 bits (852), Expect = 1e-91
Identities = 166/210 (79%), Positives = 167/210 (79%), Gaps = 43/210 (20%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCIR-------------------------------------------KPGDDSSHD 77
LTAAHCIR +PGDDSSHD
Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
Query: 78 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 137
LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS
Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180
Query: 138 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCS 167
NDVCAQVHPQKVTKFMLCAGRWTGGKSTCS
Sbjct: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCS 210
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 274 bits (700), Expect = 5e-74
Identities = 138/261 (52%), Positives = 164/261 (62%), Gaps = 44/261 (16%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MW V+ L LS+ GAAP I SRIVGGWECE+HSQPWQ + CGG+LVH QWV
Sbjct: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60
Query: 61 LTAAHCI-------------------------------------------RKPGDDSSHD 77
LTAAHCI R+ +D SHD
Sbjct: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
Query: 78 LMLLRLSEPAE-LTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVI 136
LMLLRL+EPA+ +TDAVKV++LPT+EP +G+TC ASGWGSIEPE F P LQCVDL ++
Sbjct: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
Query: 137 SNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPER 196
ND C + H QKVT FMLC G GGK TC GDSGGPL+C+GVLQG+TSWG PC P +
Sbjct: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240
Query: 197 PSLYTKVVHYRKWIKDTIVAN 217
PS+ +V+ Y KWI+DTI N
Sbjct: 241 PSVAVRVLSYVKWIEDTIAEN 261
>gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens]
Length = 223
Score = 253 bits (646), Expect = 9e-68
Identities = 126/209 (60%), Positives = 142/209 (67%), Gaps = 43/209 (20%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MW V+ + LSV GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV
Sbjct: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
Query: 61 LTAAHCIRK-------------------------------------------PGDDSSHD 77
LTAAHC++K P +DSSHD
Sbjct: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
Query: 78 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 137
LMLLRLSEPA++TD VKV+ LPTQEPALGTTCYASGWGSIEPEEFL P+ LQCV LH++S
Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
Query: 138 NDVCAQVHPQKVTKFMLCAGRWTGGKSTC 166
ND+CA+ + +KVT+FMLCAG WTGGK TC
Sbjct: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTC 209
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 192 bits (487), Expect = 2e-49
Identities = 96/225 (42%), Positives = 126/225 (56%), Gaps = 37/225 (16%)
Query: 27 GGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRK---------------PG 71
GG+ C HSQPWQ + +GR +CGGVLVHP+WVLTAAHC+++ G
Sbjct: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
Query: 72 D---------------------DSSHDLMLLRLSEPAELTDAVKVMDLPTQEPAL-GTTC 109
+ + HD+MLL L P +LT ++ + L GTTC
Sbjct: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
Query: 110 YASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGD 169
SGWG+ + PK LQC ++ + S++ C QV+P K+T MLCAG GGK +C GD
Sbjct: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
Query: 170 SGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 214
SGGPLVCN L GI SWG PC P+RP +YT+V Y WI++TI
Sbjct: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 183 bits (464), Expect = 1e-46
Identities = 88/249 (35%), Positives = 133/249 (53%), Gaps = 40/249 (16%)
Query: 5 VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA 64
++ L L+ +G +RI+ G+EC+ HSQPWQ + + R +CG L+ P+W+LTAA
Sbjct: 6 LILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61
Query: 65 HCIRK------------------------------------PGDDSSHDLMLLRLSEPAE 88
HC++ P D +D+ML++++ P
Sbjct: 62 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 121
Query: 89 LTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK 148
+T AV+ + L ++ GT+C SGWGS + P L+C ++ +I + C +P
Sbjct: 122 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 181
Query: 149 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRK 208
+T M+CA GGK +C GDSGGPLVCN LQGI SWG +PCA+ +P +YTKV Y
Sbjct: 182 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 241
Query: 209 WIKDTIVAN 217
WI++T+ N
Sbjct: 242 WIQETMKNN 250
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 183 bits (464), Expect = 1e-46
Identities = 88/249 (35%), Positives = 133/249 (53%), Gaps = 40/249 (16%)
Query: 5 VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA 64
++ L L+ +G +RI+ G+EC+ HSQPWQ + + R +CG L+ P+W+LTAA
Sbjct: 38 LILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93
Query: 65 HCIRK------------------------------------PGDDSSHDLMLLRLSEPAE 88
HC++ P D +D+ML++++ P
Sbjct: 94 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 153
Query: 89 LTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK 148
+T AV+ + L ++ GT+C SGWGS + P L+C ++ +I + C +P
Sbjct: 154 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 213
Query: 149 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRK 208
+T M+CA GGK +C GDSGGPLVCN LQGI SWG +PCA+ +P +YTKV Y
Sbjct: 214 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 273
Query: 209 WIKDTIVAN 217
WI++T+ N
Sbjct: 274 WIQETMKNN 282
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 183 bits (464), Expect = 1e-46
Identities = 88/249 (35%), Positives = 133/249 (53%), Gaps = 40/249 (16%)
Query: 5 VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA 64
++ L L+ +G +RI+ G+EC+ HSQPWQ + + R +CG L+ P+W+LTAA
Sbjct: 6 LILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61
Query: 65 HCIRK------------------------------------PGDDSSHDLMLLRLSEPAE 88
HC++ P D +D+ML++++ P
Sbjct: 62 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 121
Query: 89 LTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK 148
+T AV+ + L ++ GT+C SGWGS + P L+C ++ +I + C +P
Sbjct: 122 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 181
Query: 149 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRK 208
+T M+CA GGK +C GDSGGPLVCN LQGI SWG +PCA+ +P +YTKV Y
Sbjct: 182 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 241
Query: 209 WIKDTIVAN 217
WI++T+ N
Sbjct: 242 WIQETMKNN 250
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 180 bits (456), Expect = 1e-45
Identities = 91/229 (39%), Positives = 129/229 (56%), Gaps = 35/229 (15%)
Query: 23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRK------------ 69
SRI+ G +C+ H+QPWQ + R + CG VLVHPQW+LTAAHC +K
Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
Query: 70 ------------------PG---DDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTT 108
PG S+DLML++L+ T V+ +++ + P+ GT
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTK 184
Query: 109 CYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSG 168
C SGWG+ + + PK LQC+++ V+S C +P+++ M CAG G+ +C G
Sbjct: 185 CLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDSCQG 243
Query: 169 DSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 217
DSGGP+VCNG LQG+ SWG PCA P RP +YT + + KWI++TI AN
Sbjct: 244 DSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 180 bits (456), Expect = 1e-45
Identities = 91/229 (39%), Positives = 129/229 (56%), Gaps = 35/229 (15%)
Query: 23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRK------------ 69
SRI+ G +C+ H+QPWQ + R + CG VLVHPQW+LTAAHC +K
Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
Query: 70 ------------------PG---DDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTT 108
PG S+DLML++L+ T V+ +++ + P+ GT
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTK 184
Query: 109 CYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSG 168
C SGWG+ + + PK LQC+++ V+S C +P+++ M CAG G+ +C G
Sbjct: 185 CLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDSCQG 243
Query: 169 DSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 217
DSGGP+VCNG LQG+ SWG PCA P RP +YT + + KWI++TI AN
Sbjct: 244 DSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 180 bits (456), Expect = 1e-45
Identities = 91/229 (39%), Positives = 129/229 (56%), Gaps = 35/229 (15%)
Query: 23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRK------------ 69
SRI+ G +C+ H+QPWQ + R + CG VLVHPQW+LTAAHC +K
Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
Query: 70 ------------------PG---DDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTT 108
PG S+DLML++L+ T V+ +++ + P+ GT
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTK 184
Query: 109 CYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSG 168
C SGWG+ + + PK LQC+++ V+S C +P+++ M CAG G+ +C G
Sbjct: 185 CLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDSCQG 243
Query: 169 DSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 217
DSGGP+VCNG LQG+ SWG PCA P RP +YT + + KWI++TI AN
Sbjct: 244 DSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 178 bits (451), Expect = 4e-45
Identities = 96/250 (38%), Positives = 138/250 (55%), Gaps = 39/250 (15%)
Query: 4 PVVFLTLSVTWIGAAPLILS-----RIVGGWECEKHSQPWQ--VLVASRGRAVCGGVLVH 56
P +FL L+ + A + S +I+GG C + SQPWQ +L R R +CGG L+
Sbjct: 15 PKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLS 74
Query: 57 PQWVLTAAHC-----------------------------IRKPGDDS---SHDLMLLRLS 84
QWV+TAAHC + P +S +DLMLL+L
Sbjct: 75 GQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQ 134
Query: 85 EPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV 144
+PA + AV+ +++ + GT+C SGWG+I P LQCV++++ ++VC +
Sbjct: 135 QPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKA 194
Query: 145 HPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVV 204
+P+ +T M+CAG GGK +C GDSGGPLVC G LQG+ SWG E CALP P +YT +
Sbjct: 195 YPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLC 254
Query: 205 HYRKWIKDTI 214
YR WI++T+
Sbjct: 255 KYRSWIEETM 264
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 177 bits (448), Expect = 8e-45
Identities = 99/246 (40%), Positives = 133/246 (54%), Gaps = 34/246 (13%)
Query: 4 PVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTA 63
P++ LT + A +IVGG+ CE++S P+QV + S G CGG L++ QWV++A
Sbjct: 3 PLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNS-GYHFCGGSLINEQWVVSA 61
Query: 64 AHC-----------------------------IRKPGDDS---SHDLMLLRLSEPAELTD 91
HC IR P D ++D+ML++LS A +
Sbjct: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINA 121
Query: 92 AVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTK 151
V + LPT PA GT C SGWG+ P +LQC+D V+S C +P K+T
Sbjct: 122 RVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITS 181
Query: 152 FMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 211
M C G GGK +C GDSGGP+VCNG LQG+ SWG + CA +P +YTKV +Y KWIK
Sbjct: 182 NMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIK 240
Query: 212 DTIVAN 217
+TI AN
Sbjct: 241 NTIAAN 246
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 175 bits (443), Expect = 3e-44
Identities = 101/259 (38%), Positives = 132/259 (50%), Gaps = 45/259 (17%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MW+ LTLS A +++ G EC HSQPWQV + RGR CG L+ P WV
Sbjct: 1 MWL---LLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWV 57
Query: 61 LTAAHC-------------IRKPG-----------------DDSSH--DLMLLRLSEPAE 88
L+AAHC +RK + SH D+MLLRL +PA
Sbjct: 58 LSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPAR 117
Query: 89 LTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLT----------PKKLQCVDLHVISN 138
L V+ LPT+ P G C SGWG + E T P L C ++ +IS+
Sbjct: 118 LNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISD 177
Query: 139 DVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPS 198
C + +P ++T M+CAG G +C GDSGGPLVC G+LQGI SWG PC +P
Sbjct: 178 TSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPG 237
Query: 199 LYTKVVHYRKWIKDTIVAN 217
+YTKV HY +WI++T+ N
Sbjct: 238 VYTKVCHYLEWIRETMKRN 256
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 174 bits (440), Expect = 7e-44
Identities = 99/244 (40%), Positives = 131/244 (53%), Gaps = 38/244 (15%)
Query: 10 LSVTWIGAAPLIL----SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65
L + ++GAA + +IVGG+ CE++S P+QV + S G CGG L+ QWV++AAH
Sbjct: 5 LILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAH 63
Query: 66 C-----------------------------IRKPG---DDSSHDLMLLRLSEPAELTDAV 93
C IR P D +D+ML++LS PA + V
Sbjct: 64 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV 123
Query: 94 KVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFM 153
+ LPT PA GT C SGWG+ P +L+C+D V++ C +P K+T M
Sbjct: 124 STISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSM 183
Query: 154 LCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 213
C G GGK +C DSGGP+VCNG LQG+ SWG CA RP +YTKV +Y WIKDT
Sbjct: 184 FCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDT 242
Query: 214 IVAN 217
I AN
Sbjct: 243 IAAN 246
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 172 bits (437), Expect = 2e-43
Identities = 95/226 (42%), Positives = 123/226 (54%), Gaps = 34/226 (15%)
Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHC----------------- 66
+IVGG+ CE++S P+QV + S G CGG L+ QWV++AAHC
Sbjct: 80 KIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVL 138
Query: 67 ------------IRKPG---DDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYA 111
IR P D +D+ML++LS PA + V + LPT PA GT C
Sbjct: 139 EGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECLI 198
Query: 112 SGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSG 171
SGWG+ P +L+C+D V++ C +P K+T M C G GGK +C DSG
Sbjct: 199 SGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSG 258
Query: 172 GPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 217
GP+VCNG LQG+ SWG CA RP +YTKV +Y WIKDTI AN
Sbjct: 259 GPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 303
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 172 bits (436), Expect = 2e-43
Identities = 85/227 (37%), Positives = 121/227 (53%), Gaps = 38/227 (16%)
Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRKP------------ 70
+R +G EC +SQPWQ + R CG L+ +W+LTAAHC RKP
Sbjct: 21 TRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHC-RKPYLWVRLGEHHLW 79
Query: 71 -------------------------GDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPAL 105
+D + D+ML+RL A L+ AV+ ++L +
Sbjct: 80 KWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQPLNLSQTCVSP 139
Query: 106 GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKST 165
G C SGWG++ + L P LQC ++ ++ N +C +P ++ MLCAG W GG+ +
Sbjct: 140 GMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLWEGGRGS 199
Query: 166 CSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 212
C GDSGGPLVCNG L G+ S G+EPC+ P RP++YT V HY WI++
Sbjct: 200 CQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQE 246
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 171 bits (433), Expect = 4e-43
Identities = 93/243 (38%), Positives = 122/243 (50%), Gaps = 38/243 (15%)
Query: 8 LTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI 67
L L W G + +++GG EC+ HSQPWQ + + +CGGVLV WVLTAAHC
Sbjct: 16 LLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC- 74
Query: 68 RKP------GD------------------------------DSSHDLMLLRLSEPAELTD 91
+KP GD D +HDLMLL+L + A L
Sbjct: 75 KKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGS 134
Query: 92 AVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTK 151
VK + L G C SGWG++ P L C ++ + C +P ++T
Sbjct: 135 KVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITD 194
Query: 152 FMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 211
M+CAG + G TC GDSGGPLVC+G LQGITSWGS+PC ++P +YT + Y WIK
Sbjct: 195 GMVCAGS-SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIK 253
Query: 212 DTI 214
I
Sbjct: 254 KII 256
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 171 bits (432), Expect = 6e-43
Identities = 88/227 (38%), Positives = 126/227 (55%), Gaps = 36/227 (15%)
Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRKPG----------- 71
+++V G C+K S P+Q + + G +CGGVL+HP WVLTAAHC +KP
Sbjct: 20 NKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC-KKPNLQVFLGKHNLR 78
Query: 72 --------------------DDSSHD--LMLLRLSEPAELTDAVKVMDLPTQEPALGTTC 109
D +SHD +MLLRL+ PA+L++ ++ + L A T+C
Sbjct: 79 QRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSC 138
Query: 110 YASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGD 169
+ GWG +F P +QC +H++S + C +P ++T+ MLCAG GK +C GD
Sbjct: 139 HILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGD 196
Query: 170 SGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 216
SGGPLVC L+G+ SWG+ PC E+P +YT V Y WI+ TI A
Sbjct: 197 SGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 171 bits (432), Expect = 6e-43
Identities = 88/227 (38%), Positives = 126/227 (55%), Gaps = 36/227 (15%)
Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRKPG----------- 71
+++V G C+K S P+Q + + G +CGGVL+HP WVLTAAHC +KP
Sbjct: 20 NKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC-KKPNLQVFLGKHNLR 78
Query: 72 --------------------DDSSHD--LMLLRLSEPAELTDAVKVMDLPTQEPALGTTC 109
D +SHD +MLLRL+ PA+L++ ++ + L A T+C
Sbjct: 79 QRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSC 138
Query: 110 YASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGD 169
+ GWG +F P +QC +H++S + C +P ++T+ MLCAG GK +C GD
Sbjct: 139 HILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGD 196
Query: 170 SGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 216
SGGPLVC L+G+ SWG+ PC E+P +YT V Y WI+ TI A
Sbjct: 197 SGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 170 bits (431), Expect = 8e-43
Identities = 89/221 (40%), Positives = 120/221 (54%), Gaps = 30/221 (13%)
Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHC----------------- 66
+I+ G C + S PWQV + S + CGGVLV+ +WVLTAAHC
Sbjct: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDR 88
Query: 67 ----------IRKPGDDSS---HDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASG 113
R PG + +DLML++L+ A L+ VK + LP++ GTTC SG
Sbjct: 89 RAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSG 148
Query: 114 WGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGP 173
WG+ + P L CVD+ +IS C +V+ + MLCAG K+ C+GDSGGP
Sbjct: 149 WGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGP 208
Query: 174 LVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 214
LVC G LQG+ SWG+ PC P P +YT+V + KWI DT+
Sbjct: 209 LVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 170 bits (431), Expect = 8e-43
Identities = 89/221 (40%), Positives = 120/221 (54%), Gaps = 30/221 (13%)
Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHC----------------- 66
+I+ G C + S PWQV + S + CGGVLV+ +WVLTAAHC
Sbjct: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDR 88
Query: 67 ----------IRKPGDDSS---HDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASG 113
R PG + +DLML++L+ A L+ VK + LP++ GTTC SG
Sbjct: 89 RAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSG 148
Query: 114 WGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGP 173
WG+ + P L CVD+ +IS C +V+ + MLCAG K+ C+GDSGGP
Sbjct: 149 WGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGP 208
Query: 174 LVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 214
LVC G LQG+ SWG+ PC P P +YT+V + KWI DT+
Sbjct: 209 LVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 168 bits (425), Expect = 4e-42
Identities = 100/246 (40%), Positives = 130/246 (52%), Gaps = 38/246 (15%)
Query: 8 LTLSVTWIGAAPLIL----SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTA 63
L L +T++ AA +IVGG+ CE++S P+QV + S G CGG L+ QWV++A
Sbjct: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNS-GYHFCGGSLISEQWVVSA 61
Query: 64 AHC-----------------------------IRKPGDDS---SHDLMLLRLSEPAELTD 91
HC IR P +S +D++L++LS PA +
Sbjct: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINS 121
Query: 92 AVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTK 151
V + LPT PA GT SGWG+ P +LQC+D V+S C +P K+T
Sbjct: 122 RVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITN 181
Query: 152 FMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 211
M C G GGK +C GDSGGP+V NG LQGI SWG CA RP +YTKV +Y WIK
Sbjct: 182 NMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIK 240
Query: 212 DTIVAN 217
DTI AN
Sbjct: 241 DTIAAN 246
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 167 bits (423), Expect = 6e-42
Identities = 89/227 (39%), Positives = 117/227 (51%), Gaps = 38/227 (16%)
Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRKP------GD----- 72
+++GG EC+ HSQPWQ + + +CGGVLV WVLTAAHC +KP GD
Sbjct: 77 KVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC-KKPKYTVRLGDHSLQN 135
Query: 73 -------------------------DSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGT 107
D +HDLMLL+L + A L VK + L G
Sbjct: 136 KDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQ 195
Query: 108 TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCS 167
C SGWG++ P L C ++ + C +P ++T M+CAG + G TC
Sbjct: 196 KCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS-SKGADTCQ 254
Query: 168 GDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 214
GDSGGPLVC+G LQGITSWGS+PC ++P +YT + Y WIK I
Sbjct: 255 GDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 162 bits (410), Expect = 2e-40
Identities = 81/228 (35%), Positives = 120/228 (52%), Gaps = 35/228 (15%)
Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR-------------- 68
S+I+ G +C HSQPWQ + C GVLVHPQWVL+AAHC +
Sbjct: 29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88
Query: 69 --KPGDDS-----------------SHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTC 109
+PG ++DLML++L E +D ++ + + +Q P G +C
Sbjct: 89 DQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSC 148
Query: 110 YASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGD 169
SGWG + P LQCV++ V+S +VC++++ M CAG K +C+GD
Sbjct: 149 LVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGD 206
Query: 170 SGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 217
SGGPL+CNG LQG+ S+G PC P +YT + + +WI+ T+ A+
Sbjct: 207 SGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 157 bits (398), Expect = 5e-39
Identities = 91/241 (37%), Positives = 120/241 (49%), Gaps = 38/241 (15%)
Query: 6 VFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65
+FL L V +G + +I G EC ++SQPWQV + CGGVL+ +WVLTAAH
Sbjct: 5 IFLLLCV--LGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
Query: 66 C-----------------------------IRKPG-----DDSSHDLMLLRLSEPAELTD 91
C + PG HDL LLRL P +T
Sbjct: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTS 122
Query: 92 AVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTK 151
+V+ + LP GT C+ SGWG P LQC++L ++S+ C V+P ++T
Sbjct: 123 SVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITS 182
Query: 152 FMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGS-EPCALPERPSLYTKVVHYRKWI 210
M+CAG G+ C GDSGGPLVC GVLQG+ SWGS PC P +YT + Y WI
Sbjct: 183 NMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWI 241
Query: 211 K 211
+
Sbjct: 242 R 242
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 150 bits (380), Expect = 6e-37
Identities = 88/233 (37%), Positives = 116/233 (49%), Gaps = 38/233 (16%)
Query: 6 VFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65
+FL L V +G + +I G EC ++SQPWQV + CGGVL+ +WVLTAAH
Sbjct: 5 IFLLLCV--LGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
Query: 66 C-----------------------------IRKPG-----DDSSHDLMLLRLSEPAELTD 91
C + PG HDL LLRL P +T
Sbjct: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTS 122
Query: 92 AVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTK 151
+V+ + LP GT C+ SGWG P LQC++L ++S+ C V+P ++T
Sbjct: 123 SVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITS 182
Query: 152 FMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGS-EPCALPERPSLYTKV 203
M+CAG G+ C GDSGGPLVC GVLQG+ SWGS PC P +YT +
Sbjct: 183 NMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYI 234
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,790,616
Number of Sequences: 37866
Number of extensions: 457161
Number of successful extensions: 1525
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 169
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 936
Number of HSP's gapped (non-prelim): 337
length of query: 218
length of database: 18,247,518
effective HSP length: 98
effective length of query: 120
effective length of database: 14,536,650
effective search space: 1744398000
effective search space used: 1744398000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.