Guide to the Human Genome
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Search of human proteins with 70995396

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|70995396 NAD(P)H menadione oxidoreductase 1,
dioxin-inducible isoform b [Homo sapiens]
         (240 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|70995396 NAD(P)H menadione oxidoreductase 1, dioxin-inducible...   490   e-139
gi|4505415 NAD(P)H menadione oxidoreductase 1, dioxin-inducible ...   473   e-134
gi|70995422 NAD(P)H menadione oxidoreductase 1, dioxin-inducible...   395   e-110
gi|156564357 NAD(P)H dehydrogenase, quinone 2 [Homo sapiens]          167   6e-42
gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo sa...    29   3.2  
gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo sa...    29   3.2  
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]          29   3.2  

>gi|70995396 NAD(P)H menadione oxidoreductase 1, dioxin-inducible
           isoform b [Homo sapiens]
          Length = 240

 Score =  490 bits (1261), Expect = e-139
 Identities = 240/240 (100%), Positives = 240/240 (100%)

Query: 1   MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
           MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
Sbjct: 1   MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60

Query: 61  KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 120
           KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
Sbjct: 61  KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 120

Query: 121 FIGEFAYTYAAMYDKGPFRSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLEN 180
           FIGEFAYTYAAMYDKGPFRSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLEN
Sbjct: 121 FIGEFAYTYAAMYDKGPFRSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLEN 180

Query: 181 IWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 240
           IWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
Sbjct: 181 IWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 240


>gi|4505415 NAD(P)H menadione oxidoreductase 1, dioxin-inducible
           isoform a [Homo sapiens]
          Length = 274

 Score =  473 bits (1216), Expect = e-134
 Identities = 240/274 (87%), Positives = 240/274 (87%), Gaps = 34/274 (12%)

Query: 1   MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
           MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
Sbjct: 1   MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60

Query: 61  KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 120
           KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
Sbjct: 61  KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 120

Query: 121 FIGEFAYTYAAMYDKGPFR----------------------------------SGILHFC 146
           FIGEFAYTYAAMYDKGPFR                                  SGILHFC
Sbjct: 121 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC 180

Query: 147 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 206
           GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
Sbjct: 181 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 240

Query: 207 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 240
           KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
Sbjct: 241 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 274


>gi|70995422 NAD(P)H menadione oxidoreductase 1, dioxin-inducible
           isoform c [Homo sapiens]
          Length = 236

 Score =  395 bits (1016), Expect = e-110
 Identities = 208/247 (84%), Positives = 212/247 (85%), Gaps = 18/247 (7%)

Query: 1   MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
           MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
Sbjct: 1   MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60

Query: 61  KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 120
           KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQ         A+L      +
Sbjct: 61  KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQ------SKKAVLS-----I 109

Query: 121 FIGEFAYTYAAMYDKG-------PFRSGILHFCGFQVLEPQLTYSIGHTPADARIQILEG 173
             G     Y+     G       P +SGILHFCGFQVLEPQLTYSIGHTPADARIQILEG
Sbjct: 110 TTGGSGSMYSLQGIHGDMNVILWPIQSGILHFCGFQVLEPQLTYSIGHTPADARIQILEG 169

Query: 174 WKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTD 233
           WKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTD
Sbjct: 170 WKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTD 229

Query: 234 NQIKARK 240
           NQIKARK
Sbjct: 230 NQIKARK 236


>gi|156564357 NAD(P)H dehydrogenase, quinone 2 [Homo sapiens]
          Length = 231

 Score =  167 bits (424), Expect = 6e-42
 Identities = 91/221 (41%), Positives = 117/221 (52%), Gaps = 34/221 (15%)

Query: 1   MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
           M G++ LIV AH E  SFN ++K  A   L ++G  V  SDLYAMN  P  + KDITG L
Sbjct: 1   MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL 60

Query: 61  KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 120
            +P  F Y  E+  AYK+  L+ DI  EQKK+  ADLVIFQFPL WF VPAILKGW +RV
Sbjct: 61  SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV 120

Query: 121 FIGEFAYTYAAMYDKG----------------------------------PFRSGILHFC 146
               FA+     YD G                                  P + G LHFC
Sbjct: 121 LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC 180

Query: 147 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPL 187
           GF+VL PQ++++      + R  ++  W +RL+ IW E P+
Sbjct: 181 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPI 221


>gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo
            sapiens]
          Length = 2316

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 12/22 (54%), Positives = 15/22 (68%)

Query: 213  EKNKKFGLSVGHHLGKSIPTDN 234
            E+N KFG+  G +LG S P DN
Sbjct: 1184 EENPKFGIGKGKNLGVSFPKDN 1205


>gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo
            sapiens]
          Length = 2342

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 12/22 (54%), Positives = 15/22 (68%)

Query: 213  EKNKKFGLSVGHHLGKSIPTDN 234
            E+N KFG+  G +LG S P DN
Sbjct: 1210 EENPKFGIGKGKNLGVSFPKDN 1231


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 12/35 (34%), Positives = 18/35 (51%)

Query: 141 GILHFCGFQVLEPQLTYSIGHTPADARIQILEGWK 175
           G  H CG  +++ Q   +  H     R ++LEGWK
Sbjct: 346 GTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWK 380


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,917,504
Number of Sequences: 37866
Number of extensions: 387043
Number of successful extensions: 685
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 675
Number of HSP's gapped (non-prelim): 9
length of query: 240
length of database: 18,247,518
effective HSP length: 99
effective length of query: 141
effective length of database: 14,498,784
effective search space: 2044328544
effective search space used: 2044328544
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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