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Search of human proteins with 7019387
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7019387 G protein-coupled receptor 132 [Homo sapiens]
(380 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7019387 G protein-coupled receptor 132 [Homo sapiens] 772 0.0
gi|4885335 G protein-coupled receptor 4 [Homo sapiens] 197 2e-50
gi|40217829 G protein-coupled receptor 68 [Homo sapiens] 167 1e-41
gi|33695104 G protein-coupled receptor 65 [Homo sapiens] 159 5e-39
gi|4505557 purinergic receptor P2Y1 [Homo sapiens] 137 2e-32
gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens] 132 5e-31
gi|31083344 chemokine orphan receptor 1 [Homo sapiens] 132 5e-31
gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] 130 1e-30
gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] 130 1e-30
gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] 130 1e-30
gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] 130 1e-30
gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo sap... 125 5e-29
gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sa... 125 6e-29
gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sa... 125 6e-29
gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sap... 125 6e-29
gi|4758326 coagulation factor II (thrombin) receptor-like 2 prec... 121 9e-28
gi|219281887 lysophosphatidic acid receptor 5 [Homo sapiens] 120 2e-27
gi|9966879 lysophosphatidic acid receptor 5 [Homo sapiens] 120 2e-27
gi|4506241 platelet-activating factor receptor [Homo sapiens] 114 1e-25
gi|166362740 coagulation factor II receptor precursor [Homo sapi... 114 1e-25
gi|34577052 coagulation factor II (thrombin) receptor-like 1 pre... 112 4e-25
gi|28872720 purinergic receptor P2Y2 [Homo sapiens] 112 7e-25
gi|28872745 purinergic receptor P2Y2 [Homo sapiens] 112 7e-25
gi|28872743 purinergic receptor P2Y2 [Homo sapiens] 112 7e-25
gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens] 111 1e-24
gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo ... 110 2e-24
gi|20544172 bradykinin receptor B1 [Homo sapiens] 110 3e-24
gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens] 109 4e-24
gi|14211849 putative purinergic receptor FKSG79 [Homo sapiens] 106 3e-23
gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens] 105 5e-23
>gi|7019387 G protein-coupled receptor 132 [Homo sapiens]
Length = 380
Score = 772 bits (1993), Expect = 0.0
Identities = 380/380 (100%), Positives = 380/380 (100%)
Query: 1 MCPMLLKNGYNGNATPVTTTAPWASLGLSAKTCNNVSFEESRIVLVVVYSAVCTLGVPAN 60
MCPMLLKNGYNGNATPVTTTAPWASLGLSAKTCNNVSFEESRIVLVVVYSAVCTLGVPAN
Sbjct: 1 MCPMLLKNGYNGNATPVTTTAPWASLGLSAKTCNNVSFEESRIVLVVVYSAVCTLGVPAN 60
Query: 61 CLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHRWTLGLLACKVTAY 120
CLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHRWTLGLLACKVTAY
Sbjct: 61 CLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHRWTLGLLACKVTAY 120
Query: 121 IFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIFILVGIVHYPVFQT 180
IFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIFILVGIVHYPVFQT
Sbjct: 121 IFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIFILVGIVHYPVFQT 180
Query: 181 EDKETCFDMLQMDSRIAGYYYARFTVGFAIPLSIIAFTNHRIFRSIKQSMGLSAAQKAKV 240
EDKETCFDMLQMDSRIAGYYYARFTVGFAIPLSIIAFTNHRIFRSIKQSMGLSAAQKAKV
Sbjct: 181 EDKETCFDMLQMDSRIAGYYYARFTVGFAIPLSIIAFTNHRIFRSIKQSMGLSAAQKAKV 240
Query: 241 KHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYTASVVFLCLSTVN 300
KHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYTASVVFLCLSTVN
Sbjct: 241 KHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYTASVVFLCLSTVN 300
Query: 301 GVADPIIYVLATDHSRQEVSRIHKGWKEWSMKTDVTRLTHSRDTEELQSPVALADHYTFS 360
GVADPIIYVLATDHSRQEVSRIHKGWKEWSMKTDVTRLTHSRDTEELQSPVALADHYTFS
Sbjct: 301 GVADPIIYVLATDHSRQEVSRIHKGWKEWSMKTDVTRLTHSRDTEELQSPVALADHYTFS 360
Query: 361 RPVHPPGSPCPAKRLIEESC 380
RPVHPPGSPCPAKRLIEESC
Sbjct: 361 RPVHPPGSPCPAKRLIEESC 380
>gi|4885335 G protein-coupled receptor 4 [Homo sapiens]
Length = 362
Score = 197 bits (500), Expect = 2e-50
Identities = 106/281 (37%), Positives = 165/281 (58%), Gaps = 11/281 (3%)
Query: 48 VYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHR 107
+Y V +G+P NCL W A QV Q N L VYL+ L++ +LLY TLPLWV Y +
Sbjct: 23 LYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDN 82
Query: 108 WTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIF 167
W G +CK+ +IF+ NIY+SI FLCCIS DR++AV + L RR +TA+ +S+ ++
Sbjct: 83 WIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVW 142
Query: 168 IL-VGIVHYPVFQTE------DKETCFDMLQMDSRIAGYYYARFTVGFAIPLSIIAFTNH 220
+G P+F E + CF+ M+ +A R VGF P +++ +
Sbjct: 143 ATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAWMNLYRVFVGFLFPWALMLLSYR 202
Query: 221 RIFRSIKQSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAMC 280
I R+++ S+ +KAK+K A++++ I LVCFAPYH++LL ++A + D C
Sbjct: 203 GILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRPWD----C 258
Query: 281 GLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSR 321
G EER+++A L +++N VADPI+Y L + +R +V++
Sbjct: 259 GFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAK 299
>gi|40217829 G protein-coupled receptor 68 [Homo sapiens]
Length = 375
Score = 167 bits (424), Expect = 1e-41
Identities = 89/283 (31%), Positives = 155/283 (54%), Gaps = 15/283 (5%)
Query: 47 VVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQH 106
VVY V +G PANCL+ + LQ+ N L VYL L + +L Y +LP W+ Y+
Sbjct: 36 VVYVTVLVVGFPANCLSLYFGYLQIKARNELGVYLCNLTVADLFYICSLPFWLQYVLQHD 95
Query: 107 RWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACI 166
W+ G L+C+V + + NIY+S+ FLCCIS DR++AV + R + A+ +S I
Sbjct: 96 NWSHGDLSCQVCGILLYENIYISVGFLCCISVDRYLAVAHPFRFHQFRTLKAAVGVSVVI 155
Query: 167 FI------LVGIVHYPVFQTEDK-ETCFDMLQMDSRIAGYYYARFTVGFAIPLSIIAFTN 219
+ + ++H V + E++ CF+ + + Y RF VGF P+ ++ +
Sbjct: 156 WAKELLTSIYFLMHEEVIEDENQHRVCFEHYPIQAWQRAINYYRFLVGFLFPICLLLASY 215
Query: 220 HRIFRSIKQSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAM 279
I R++++S G ++K +++ ++ VVIFL CF PYH++LLV++ A
Sbjct: 216 QGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLACFLPYHVLLLVRSV--------WEAS 267
Query: 280 CGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRI 322
C + ++ A L L++ N VADP++Y ++ + ++++R+
Sbjct: 268 CDFAKGVFNAYHFSLLLTSFNCVADPVLYCFVSETTHRDLARL 310
>gi|33695104 G protein-coupled receptor 65 [Homo sapiens]
Length = 337
Score = 159 bits (401), Expect = 5e-39
Identities = 90/305 (29%), Positives = 157/305 (51%), Gaps = 14/305 (4%)
Query: 32 TCNNVSFEESRIVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLY 91
TC + + +VY V + +PAN + ++ LQ + + L +YL L+L +LLY
Sbjct: 4 TCIEEQHDLDHYLFPIVYIFVIIVSIPANIGSLCVSFLQAKKESELGIYLFSLSLSDLLY 63
Query: 92 TGTLPLWVIYIRNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESR 151
TLPLW+ Y N+ WT CK +A++ + N Y S FL CI+ DR++AVVY L+
Sbjct: 64 ALTLPLWIDYTWNKDNWTFSPALCKGSAFLMYMNFYSSTAFLTCIAVDRYLAVVYPLKFF 123
Query: 152 GRRRRRTAILISACIFILVGI------------VHYPVFQTEDKETCFDMLQMDSRIAGY 199
R RR A+++S I+IL I V Y + + C+D ++
Sbjct: 124 FLRTRRFALMVSLSIWILETIFNAVMLWEDETVVEYCDAEKSNFTLCYDKYPLEKWQINL 183
Query: 200 YYARFTVGFAIPLSIIAFTNHRIFRSIKQSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYH 259
R G+AIPL I N +++++++ + +K ++ +++ V F++CF P+H
Sbjct: 184 NLFRTCTGYAIPLVTILICNRKVYQAVRHNKATENKEKKRIIKLLVSITVTFVLCFTPFH 243
Query: 260 LVLLVKAAAFSYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEV 319
++LL++ + ++ G +R YT + + L+++N VADPI+Y T+ R ++
Sbjct: 244 VMLLIRCILEHAVNFEDHSNSG--KRTYTMYRITVALTSLNCVADPILYCFVTETGRYDM 301
Query: 320 SRIHK 324
I K
Sbjct: 302 WNILK 306
>gi|4505557 purinergic receptor P2Y1 [Homo sapiens]
Length = 373
Score = 137 bits (344), Expect = 2e-32
Identities = 96/319 (30%), Positives = 156/319 (48%), Gaps = 16/319 (5%)
Query: 12 GNATPVTTTAPWASLGLSAKTCNNVSFEESRIVLVVVYSAVCTLGVPANCLTAWLALLQV 71
GN+T V +TA +S A T F L VY V +G N + W+ + +
Sbjct: 26 GNST-VASTAAVSSSFKCALTKTGFQF----YYLPAVYILVFIIGFLGNSVAIWMFVFHM 80
Query: 72 LQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHRWTLGLLACKVTAYIFFCNIYVSIL 131
+ ++VY+ LAL + LY TLP + Y N+ W G CK+ +IF N+Y SIL
Sbjct: 81 KPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSIL 140
Query: 132 FLCCISCDRFVAVVYALESRGRRRRRTAILISACIFILVGIVHYPVF-------QTEDKE 184
FL CIS R+ VVY L+S GR +++ AI IS ++++V + P+ +
Sbjct: 141 FLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTI 200
Query: 185 TCFDMLQMDSRIAGYYYARFT--VGFAIPLSIIAFTNHRIFRSIKQSMGLSAAQKAKVKH 242
TC+D + + + Y+ T F +PL +I I R++ ++ + K +
Sbjct: 201 TCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIY 260
Query: 243 SAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYTASVVFLCLSTVNGV 302
I V+ +F V + P+H++ + A ++ AMC +R+Y V L+++N
Sbjct: 261 LVIIVLTVFAVSYIPFHVMKTMNLRARLDFQ--TPAMCAFNDRVYATYQVTRGLASLNSC 318
Query: 303 ADPIIYVLATDHSRQEVSR 321
DPI+Y LA D R+ +SR
Sbjct: 319 VDPILYFLAGDTFRRRLSR 337
>gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens]
Length = 370
Score = 132 bits (332), Expect = 5e-31
Identities = 90/274 (32%), Positives = 140/274 (51%), Gaps = 20/274 (7%)
Query: 48 VYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHR 107
VYS V LG+ N ++ ++ ++ + A+++ LA+ +LL+ TLP + Y N+H
Sbjct: 45 VYSVVFILGLITNSVSLFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKIFYNFNRH- 103
Query: 108 WTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIF 167
W G CK++ F NIY S+LFL CIS DRF+A+VY SR R RR + ++ A ++
Sbjct: 104 WPFGDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGVW 163
Query: 168 ILV--GIVHYPVFQTED----KETCFDMLQMDSRIAGYYYARFT-----VGFAIPLSIIA 216
ILV G + +F T + TCF+ R+ Y ++ T VGF IPL +
Sbjct: 164 ILVLSGGISASLFSTTNVNNATTTCFE--GFSKRVWKTYLSKITIFIEVVGFIIPLILNV 221
Query: 217 FTNHRIFRSIKQSMGLS--AAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRG 274
+ + R++++ LS K KV + +F+VCF PY+ VL + ++ R
Sbjct: 222 SCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLFL----YALVRS 277
Query: 275 DRNAMCGLEERLYTASVVFLCLSTVNGVADPIIY 308
C LE + LCL+T+N DP IY
Sbjct: 278 QAITNCFLERFAKIMYPITLCLATLNCCFDPFIY 311
>gi|31083344 chemokine orphan receptor 1 [Homo sapiens]
Length = 362
Score = 132 bits (332), Expect = 5e-31
Identities = 88/315 (27%), Positives = 152/315 (48%), Gaps = 19/315 (6%)
Query: 45 LVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRN 104
L +Y + +G+ AN + W+ + G Y+L LA+ +L T+P+WV+ +
Sbjct: 47 LSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQ 106
Query: 105 QHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISA 164
++W +G L CKVT IF N++ SI FL C+S DR++++ Y + R++ ++
Sbjct: 107 HNQWPMGELTCKVTHLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCI 166
Query: 165 CIFILVGIVHYP-------VFQTEDKET----CFDMLQMDSRIAGYYYARFTVGFAIPLS 213
+++L V P V + ET + + + G +GFA+P S
Sbjct: 167 LVWLLAFCVSLPDTYYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFS 226
Query: 214 IIAFTNHRIFRSIKQSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYR 273
IIA + R+I S S +K + + VV+FLVC+ PYH+ +L+ + +Y
Sbjct: 227 IIAVFYFLLARAISAS---SDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHY- 282
Query: 274 GDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRIHKGWKEWSMKT 333
C LE L+TA V CLS V+ +P++Y + R E+ + ++S KT
Sbjct: 283 --IPFTCRLEHALFTALHVTQCLSLVHCCVNPVLYSFINRNYRYELMKAF--IFKYSAKT 338
Query: 334 DVTRLTHSRDTEELQ 348
+T+L + E +
Sbjct: 339 GLTKLIDASRVSETE 353
>gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 130 bits (328), Expect = 1e-30
Identities = 78/274 (28%), Positives = 129/274 (47%), Gaps = 12/274 (4%)
Query: 55 LGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHRWTLGLLA 114
L + N L WL + G V+L+ LA+ +L LP ++Y + + W G +A
Sbjct: 44 LALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIA 103
Query: 115 CKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIFILVGIVH 174
C++T ++F+ N+Y SI FL CIS DRF+A+V+ ++S RR A L A ++++V +
Sbjct: 104 CRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAM 163
Query: 175 YPVF------QTEDKETCFDMLQMDSRIAGYYYARFTVGFAIPLSIIAFTNHRIFRSIKQ 228
P+ QT C + + + + + V F P I RS++Q
Sbjct: 164 APLLVSPQTVQTNHTVVCLQLYR--EKASHHALVSLAVAFTFPFITTVTCYLLIIRSLRQ 221
Query: 229 SMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYT 288
+ + K K V+ IFLVCF PYH V + + + A C + L
Sbjct: 222 GLRVEKRLKTKAVRMIAIVLAIFLVCFVPYH----VNRSVYVLHYRSHGASCATQRILAL 277
Query: 289 ASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRI 322
A+ + CL+++NG DPI+Y + R + +
Sbjct: 278 ANRITSCLTSLNGALDPIMYFFVAEKFRHALCNL 311
>gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 130 bits (328), Expect = 1e-30
Identities = 78/274 (28%), Positives = 129/274 (47%), Gaps = 12/274 (4%)
Query: 55 LGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHRWTLGLLA 114
L + N L WL + G V+L+ LA+ +L LP ++Y + + W G +A
Sbjct: 44 LALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIA 103
Query: 115 CKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIFILVGIVH 174
C++T ++F+ N+Y SI FL CIS DRF+A+V+ ++S RR A L A ++++V +
Sbjct: 104 CRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAM 163
Query: 175 YPVF------QTEDKETCFDMLQMDSRIAGYYYARFTVGFAIPLSIIAFTNHRIFRSIKQ 228
P+ QT C + + + + + V F P I RS++Q
Sbjct: 164 APLLVSPQTVQTNHTVVCLQLYR--EKASHHALVSLAVAFTFPFITTVTCYLLIIRSLRQ 221
Query: 229 SMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYT 288
+ + K K V+ IFLVCF PYH V + + + A C + L
Sbjct: 222 GLRVEKRLKTKAVRMIAIVLAIFLVCFVPYH----VNRSVYVLHYRSHGASCATQRILAL 277
Query: 289 ASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRI 322
A+ + CL+++NG DPI+Y + R + +
Sbjct: 278 ANRITSCLTSLNGALDPIMYFFVAEKFRHALCNL 311
>gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 130 bits (328), Expect = 1e-30
Identities = 78/274 (28%), Positives = 129/274 (47%), Gaps = 12/274 (4%)
Query: 55 LGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHRWTLGLLA 114
L + N L WL + G V+L+ LA+ +L LP ++Y + + W G +A
Sbjct: 72 LALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIA 131
Query: 115 CKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIFILVGIVH 174
C++T ++F+ N+Y SI FL CIS DRF+A+V+ ++S RR A L A ++++V +
Sbjct: 132 CRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAM 191
Query: 175 YPVF------QTEDKETCFDMLQMDSRIAGYYYARFTVGFAIPLSIIAFTNHRIFRSIKQ 228
P+ QT C + + + + + V F P I RS++Q
Sbjct: 192 APLLVSPQTVQTNHTVVCLQLYR--EKASHHALVSLAVAFTFPFITTVTCYLLIIRSLRQ 249
Query: 229 SMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYT 288
+ + K K V+ IFLVCF PYH V + + + A C + L
Sbjct: 250 GLRVEKRLKTKAVRMIAIVLAIFLVCFVPYH----VNRSVYVLHYRSHGASCATQRILAL 305
Query: 289 ASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRI 322
A+ + CL+++NG DPI+Y + R + +
Sbjct: 306 ANRITSCLTSLNGALDPIMYFFVAEKFRHALCNL 339
>gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 130 bits (328), Expect = 1e-30
Identities = 78/274 (28%), Positives = 129/274 (47%), Gaps = 12/274 (4%)
Query: 55 LGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHRWTLGLLA 114
L + N L WL + G V+L+ LA+ +L LP ++Y + + W G +A
Sbjct: 72 LALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIA 131
Query: 115 CKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIFILVGIVH 174
C++T ++F+ N+Y SI FL CIS DRF+A+V+ ++S RR A L A ++++V +
Sbjct: 132 CRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAM 191
Query: 175 YPVF------QTEDKETCFDMLQMDSRIAGYYYARFTVGFAIPLSIIAFTNHRIFRSIKQ 228
P+ QT C + + + + + V F P I RS++Q
Sbjct: 192 APLLVSPQTVQTNHTVVCLQLYR--EKASHHALVSLAVAFTFPFITTVTCYLLIIRSLRQ 249
Query: 229 SMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYT 288
+ + K K V+ IFLVCF PYH V + + + A C + L
Sbjct: 250 GLRVEKRLKTKAVRMIAIVLAIFLVCFVPYH----VNRSVYVLHYRSHGASCATQRILAL 305
Query: 289 ASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRI 322
A+ + CL+++NG DPI+Y + R + +
Sbjct: 306 ANRITSCLTSLNGALDPIMYFFVAEKFRHALCNL 339
>gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo
sapiens]
Length = 359
Score = 125 bits (315), Expect = 5e-29
Identities = 81/284 (28%), Positives = 135/284 (47%), Gaps = 24/284 (8%)
Query: 43 IVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYI 102
+ L VVYS V + +P N + W+ ++ + ++++ L++ +L+ LP + Y
Sbjct: 24 VALPVVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYH 83
Query: 103 RNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILI 162
N+H W G+L C V F+ N+Y SIL + CIS +RF+ V+Y L S+ RRRR A+
Sbjct: 84 CNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAA 143
Query: 163 SACIFILVGIVHYPVFQTE--------DKETCFD-----MLQMDSRIAGYYYARFTVGFA 209
A ++L+ P+ +T+ TCFD ML + A + + F + F
Sbjct: 144 CAGTWLLLLTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIFILLFL 203
Query: 210 IPLSI-IAFTNHRIFRSIKQSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAA 268
IP I +A I + ++ Q+ + A V++ F+ CFAP + VLL +
Sbjct: 204 IPFVITVACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVS 263
Query: 269 FSYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLAT 312
+Y + Y + LCLS +N DP +Y A+
Sbjct: 264 RLFY----------GKSYYHVYKLTLCLSCLNNCLDPFVYYFAS 297
>gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 125 bits (314), Expect = 6e-29
Identities = 84/313 (26%), Positives = 148/313 (47%), Gaps = 27/313 (8%)
Query: 48 VYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHR 107
++S V LG+ +NC+ ++ + + N Y++ LA+ +LL+ TLP + Y ++
Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTRN- 81
Query: 108 WTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIF 167
W G L CK++ +F+ N+Y SILFL CIS DRF+A+VY +S+ R +R A ++ ++
Sbjct: 82 WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVW 141
Query: 168 ILVGIVHYPVFQTED--------KETCFDMLQMDSRIAGYYYARFT-----VGFAIPLSI 214
+ V P + E CF+ Y +R VGF IPL +
Sbjct: 142 LTVIGGSAPAVFVQSTHSQGNNASEACFE--NFPEATWKTYLSRIVIFIEIVGFFIPLIL 199
Query: 215 IAFTNHRIFRSIKQSMGLSAAQ--KAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYY 272
+ + +++ + + LS ++ K KV ++IF CF PY++ L++ +S
Sbjct: 200 NVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLIL----YSLV 255
Query: 273 RGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRIHKGWKEWSMK 332
R C + + T + LC++ N DPI+Y +D + + K WS++
Sbjct: 256 RTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSIK-----MKNWSVR 310
Query: 333 TDVTRLTHSRDTE 345
R + E
Sbjct: 311 RSDFRFSEVHGAE 323
>gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 125 bits (314), Expect = 6e-29
Identities = 84/313 (26%), Positives = 148/313 (47%), Gaps = 27/313 (8%)
Query: 48 VYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHR 107
++S V LG+ +NC+ ++ + + N Y++ LA+ +LL+ TLP + Y ++
Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTRN- 81
Query: 108 WTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIF 167
W G L CK++ +F+ N+Y SILFL CIS DRF+A+VY +S+ R +R A ++ ++
Sbjct: 82 WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVW 141
Query: 168 ILVGIVHYPVFQTED--------KETCFDMLQMDSRIAGYYYARFT-----VGFAIPLSI 214
+ V P + E CF+ Y +R VGF IPL +
Sbjct: 142 LTVIGGSAPAVFVQSTHSQGNNASEACFE--NFPEATWKTYLSRIVIFIEIVGFFIPLIL 199
Query: 215 IAFTNHRIFRSIKQSMGLSAAQ--KAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYY 272
+ + +++ + + LS ++ K KV ++IF CF PY++ L++ +S
Sbjct: 200 NVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLIL----YSLV 255
Query: 273 RGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRIHKGWKEWSMK 332
R C + + T + LC++ N DPI+Y +D + + K WS++
Sbjct: 256 RTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSIK-----MKNWSVR 310
Query: 333 TDVTRLTHSRDTE 345
R + E
Sbjct: 311 RSDFRFSEVHGAE 323
>gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 125 bits (314), Expect = 6e-29
Identities = 84/313 (26%), Positives = 148/313 (47%), Gaps = 27/313 (8%)
Query: 48 VYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHR 107
++S V LG+ +NC+ ++ + + N Y++ LA+ +LL+ TLP + Y ++
Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTRN- 81
Query: 108 WTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIF 167
W G L CK++ +F+ N+Y SILFL CIS DRF+A+VY +S+ R +R A ++ ++
Sbjct: 82 WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVW 141
Query: 168 ILVGIVHYPVFQTED--------KETCFDMLQMDSRIAGYYYARFT-----VGFAIPLSI 214
+ V P + E CF+ Y +R VGF IPL +
Sbjct: 142 LTVIGGSAPAVFVQSTHSQGNNASEACFE--NFPEATWKTYLSRIVIFIEIVGFFIPLIL 199
Query: 215 IAFTNHRIFRSIKQSMGLSAAQ--KAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYY 272
+ + +++ + + LS ++ K KV ++IF CF PY++ L++ +S
Sbjct: 200 NVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLIL----YSLV 255
Query: 273 RGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRIHKGWKEWSMK 332
R C + + T + LC++ N DPI+Y +D + + K WS++
Sbjct: 256 RTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSIK-----MKNWSVR 310
Query: 333 TDVTRLTHSRDTE 345
R + E
Sbjct: 311 RSDFRFSEVHGAE 323
>gi|4758326 coagulation factor II (thrombin) receptor-like 2
precursor [Homo sapiens]
Length = 374
Score = 121 bits (304), Expect = 9e-28
Identities = 88/323 (27%), Positives = 146/323 (45%), Gaps = 29/323 (8%)
Query: 3 PMLLKNGYNGNATPVTTTAPWAS---LGLSAKTCNNVSFEESRIVLVVVYSAVCTLGVPA 59
P G+ G V P S L + T ++ S ++ +Y V +GVPA
Sbjct: 52 PFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPA 111
Query: 60 NCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHRWTLGLLACKVTA 119
N +T W+ + + V+ LA+ + L+ TLP + Y N + W G + C+ T
Sbjct: 112 NAVTLWMLFFRT-RSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATT 170
Query: 120 YIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIFILVGIVHYPVFQ 179
IF+ N+Y SIL L CIS +R++A+V+ RG + A++ ++ V + P F
Sbjct: 171 VIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFI 230
Query: 180 TE--------DKETCFDM---LQMDSRIAGYYYARFT-VGFAIPLSIIAFTNHRIFRSIK 227
+ D TC D+ + S YY+ GF IP +I + I R++
Sbjct: 231 LKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLN 290
Query: 228 QSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLY 287
VK +++ ++VIF +CFAP +++L++ A + Y D LY
Sbjct: 291 ---AYDHRWLWYVK-ASLLILVIFTICFAPSNIILIIHHANYYYNNTD---------GLY 337
Query: 288 TASVVFLCLSTVNGVADPIIYVL 310
++ LCL ++N DP +Y L
Sbjct: 338 FIYLIALCLGSLNSCLDPFLYFL 360
>gi|219281887 lysophosphatidic acid receptor 5 [Homo sapiens]
Length = 372
Score = 120 bits (301), Expect = 2e-27
Identities = 85/305 (27%), Positives = 148/305 (48%), Gaps = 17/305 (5%)
Query: 46 VVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQ 105
+VVYS V G+P N L W+ L + +V++VY+ LA +LL+T +LP+ + Y
Sbjct: 26 LVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYA-L 84
Query: 106 HRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISAC 165
H W L C+ T IF N+Y S +FL I+ DR+ A+V+ L R RR R A L+
Sbjct: 85 HHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLG 144
Query: 166 IFILVGI-------VHYPV---FQTEDKETCFDMLQMD---SRIAGYYYARFTVGFAIPL 212
++ L+ + VH P ++ + CF+ + R+ +GF +PL
Sbjct: 145 VWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPL 204
Query: 213 SIIAFTNHRIFRSIKQSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYY 272
+ + +++ R+F ++ + + ++ K +A +VIFL+CF PY+ L V S
Sbjct: 205 AAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKL 264
Query: 273 RGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRIHKGWKEWSMK 332
A +R+ +V + L+ N V DP++Y + + R + + + +
Sbjct: 265 VA---ASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSA 321
Query: 333 TDVTR 337
T+ TR
Sbjct: 322 TNGTR 326
>gi|9966879 lysophosphatidic acid receptor 5 [Homo sapiens]
Length = 372
Score = 120 bits (301), Expect = 2e-27
Identities = 85/305 (27%), Positives = 148/305 (48%), Gaps = 17/305 (5%)
Query: 46 VVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQ 105
+VVYS V G+P N L W+ L + +V++VY+ LA +LL+T +LP+ + Y
Sbjct: 26 LVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYA-L 84
Query: 106 HRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISAC 165
H W L C+ T IF N+Y S +FL I+ DR+ A+V+ L R RR R A L+
Sbjct: 85 HHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLG 144
Query: 166 IFILVGI-------VHYPV---FQTEDKETCFDMLQMD---SRIAGYYYARFTVGFAIPL 212
++ L+ + VH P ++ + CF+ + R+ +GF +PL
Sbjct: 145 VWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPL 204
Query: 213 SIIAFTNHRIFRSIKQSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYY 272
+ + +++ R+F ++ + + ++ K +A +VIFL+CF PY+ L V S
Sbjct: 205 AAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKL 264
Query: 273 RGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRIHKGWKEWSMK 332
A +R+ +V + L+ N V DP++Y + + R + + + +
Sbjct: 265 VA---ASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSA 321
Query: 333 TDVTR 337
T+ TR
Sbjct: 322 TNGTR 326
>gi|4506241 platelet-activating factor receptor [Homo sapiens]
Length = 342
Score = 114 bits (286), Expect = 1e-25
Identities = 80/292 (27%), Positives = 135/292 (46%), Gaps = 24/292 (8%)
Query: 47 VVYSAVCTLGVPANCLTAWL--ALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRN 104
+VYS + LGV AN W+ L + N + ++++ L + ++L+ TLPLW++Y +N
Sbjct: 20 IVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADMLFLITLPLWIVYYQN 79
Query: 105 QHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISA 164
Q W L C V +FF N Y S+ FL I+ +RF AV +++ R+ I +S
Sbjct: 80 QGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTRKRGISLSL 139
Query: 165 CIFI-LVGIVHYPVFQTEDKET-----------CFDMLQMDSRIAGYYYARFTVGFAIPL 212
I++ +VG Y + CF+ + S + F +
Sbjct: 140 VIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKGSVPVLIIHIFIVFSFFLVF 199
Query: 213 SIIAFTNHRIFRSIKQSMGLSAAQKAKVKHSAI----AVVVIFLVCFAPYHLVLLVKAAA 268
II F N I R++ + + A+VK A+ V+ +F++CF P+H+V L A
Sbjct: 200 LIILFCNLVIIRTLLM-QPVQQQRNAEVKRRALWMVCTVLAVFIICFVPHHVVQLPWTLA 258
Query: 269 FSYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVS 320
++ + + + A V LCL + N V DP+IY T R+ ++
Sbjct: 259 ELGFQDSK-----FHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLT 305
>gi|166362740 coagulation factor II receptor precursor [Homo
sapiens]
Length = 425
Score = 114 bits (285), Expect = 1e-25
Identities = 79/287 (27%), Positives = 134/287 (46%), Gaps = 21/287 (7%)
Query: 48 VYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHR 107
VY+ V + +P N + + +L++ VY+L LA ++L+ LP + Y +
Sbjct: 108 VYTGVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSD 167
Query: 108 WTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIF 167
W G C+ F+CN+Y SIL + IS DRF+AVVY ++S R A I+
Sbjct: 168 WQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIW 227
Query: 168 ILVGIVHYPVFQTEDK--------ETCFDMLQMDSRIAGYYYARFT----VGFAIPLSII 215
L P+ E TC D+L ++ + GYY F+ V F +PL I
Sbjct: 228 ALAIAGVVPLLLKEQTIQVPGLNITTCHDVLN-ETLLEGYYAYYFSAFSAVFFFVPLIIS 286
Query: 216 AFTNHRIFRSIKQSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGD 275
I R + S + ++K++ + AV IF++CF P +++L+ + S+
Sbjct: 287 TVCYVSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSH---- 342
Query: 276 RNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRI 322
E Y A ++ +C+S+++ DP+IY A+ ++ V I
Sbjct: 343 ----TSTTEAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSI 385
>gi|34577052 coagulation factor II (thrombin) receptor-like 1
precursor [Homo sapiens]
Length = 397
Score = 112 bits (281), Expect = 4e-25
Identities = 85/325 (26%), Positives = 152/325 (46%), Gaps = 30/325 (9%)
Query: 43 IVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYI 102
+ L +VY+ V +G+P+N + W+ L + + + +Y+ LAL +LL PL + Y
Sbjct: 76 VFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYH 135
Query: 103 RNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILI 162
+ + W G C V F+ N+Y SILF+ C+S R+ +V + R++ AI I
Sbjct: 136 IHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPM-GHSRKKANIAIGI 194
Query: 163 SACIFILVGIVHYPVFQTEDK--------ETCFDMLQMDSRIAGY--YYARFTVG-FAIP 211
S I++L+ +V P++ + TC D+L + Y+ +G F P
Sbjct: 195 SLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAIGVFLFP 254
Query: 212 LSIIAFTNHRIFRSIKQSMGLSAAQKAKVKHSAIAVVVI--FLVCFAPYHLVLLVKAAAF 269
+ A + R ++ S ++K + + + V V+ +L+CF P +L+L+V
Sbjct: 255 AFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVV----- 309
Query: 270 SYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLAT----DHSRQE-VSRIHK 324
Y+ + +Y +V LCLST+N DP +Y + DH++ + R +
Sbjct: 310 HYFLIKSQG----QSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVR 365
Query: 325 GWKEWSMKTDVTRLTHSRDTEELQS 349
K+ M+ +T HSR + S
Sbjct: 366 TVKQ--MQVSLTSKKHSRKSSSYSS 388
>gi|28872720 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 112 bits (279), Expect = 7e-25
Identities = 81/282 (28%), Positives = 134/282 (47%), Gaps = 19/282 (6%)
Query: 43 IVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYI 102
++L V Y VC G+ N + ++ L ++ N Y+ LA+ + LY +LPL V Y
Sbjct: 34 VLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYY 93
Query: 103 RNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILI 162
W + CK+ ++F+ N+Y SILFL CIS R + V+ L S R R A +
Sbjct: 94 ARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRV 153
Query: 163 SACIFILVGIVHYPV--FQTED----KETCFDML--QMDSRIAGYYYARFTVGFAIPLSI 214
+ +++LV PV F T + TC D ++ SR Y + FA+P ++
Sbjct: 154 AGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAV 213
Query: 215 IAFTNHRIFRSIKQ-----SMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAF 269
I + R + + S GL A++ V+ A+ V+ +F +CF P+H + + +
Sbjct: 214 ILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAV-VLAVFALCFLPFH---VTRTLYY 269
Query: 270 SYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLA 311
S+ D + C + A V L++ N DP++Y LA
Sbjct: 270 SFRSLDLS--CHTLNAINMAYKVTRPLASANSCLDPVLYFLA 309
>gi|28872745 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 112 bits (279), Expect = 7e-25
Identities = 81/282 (28%), Positives = 134/282 (47%), Gaps = 19/282 (6%)
Query: 43 IVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYI 102
++L V Y VC G+ N + ++ L ++ N Y+ LA+ + LY +LPL V Y
Sbjct: 34 VLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYY 93
Query: 103 RNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILI 162
W + CK+ ++F+ N+Y SILFL CIS R + V+ L S R R A +
Sbjct: 94 ARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRV 153
Query: 163 SACIFILVGIVHYPV--FQTED----KETCFDML--QMDSRIAGYYYARFTVGFAIPLSI 214
+ +++LV PV F T + TC D ++ SR Y + FA+P ++
Sbjct: 154 AGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAV 213
Query: 215 IAFTNHRIFRSIKQ-----SMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAF 269
I + R + + S GL A++ V+ A+ V+ +F +CF P+H + + +
Sbjct: 214 ILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAV-VLAVFALCFLPFH---VTRTLYY 269
Query: 270 SYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLA 311
S+ D + C + A V L++ N DP++Y LA
Sbjct: 270 SFRSLDLS--CHTLNAINMAYKVTRPLASANSCLDPVLYFLA 309
>gi|28872743 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 112 bits (279), Expect = 7e-25
Identities = 81/282 (28%), Positives = 134/282 (47%), Gaps = 19/282 (6%)
Query: 43 IVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYI 102
++L V Y VC G+ N + ++ L ++ N Y+ LA+ + LY +LPL V Y
Sbjct: 34 VLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYY 93
Query: 103 RNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILI 162
W + CK+ ++F+ N+Y SILFL CIS R + V+ L S R R A +
Sbjct: 94 ARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRV 153
Query: 163 SACIFILVGIVHYPV--FQTED----KETCFDML--QMDSRIAGYYYARFTVGFAIPLSI 214
+ +++LV PV F T + TC D ++ SR Y + FA+P ++
Sbjct: 154 AGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAV 213
Query: 215 IAFTNHRIFRSIKQ-----SMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAF 269
I + R + + S GL A++ V+ A+ V+ +F +CF P+H + + +
Sbjct: 214 ILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAV-VLAVFALCFLPFH---VTRTLYY 269
Query: 270 SYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLA 311
S+ D + C + A V L++ N DP++Y LA
Sbjct: 270 SFRSLDLS--CHTLNAINMAYKVTRPLASANSCLDPVLYFLA 309
>gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens]
Length = 361
Score = 111 bits (277), Expect = 1e-24
Identities = 84/326 (25%), Positives = 148/326 (45%), Gaps = 23/326 (7%)
Query: 41 SRIVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVI 100
+RIV+ + YS V +G+ N L + + + N +Y L + ++L+T LP +
Sbjct: 30 ARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSTNLVISDILFTTALPTRIA 89
Query: 101 YIRNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAI 160
Y W +G C++TA +F+ N Y + F+ C+S DRF+AVV+ L +R A
Sbjct: 90 YYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRIEHAK 149
Query: 161 LISACIFILVGIVHYPVF------QTEDKETCFDM--LQMDSRIAGYYYARFTVGFAIPL 212
+ ++ILV P+ Q ++ TC + + + +G+ +PL
Sbjct: 150 GVCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNFEETKSLPWILLGACFIGYVLPL 209
Query: 213 SIIAFTNHRI----FRSIKQS-MGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVL---LV 264
II +I FR+ KQ+ + + K ++ I ++V+F++CF PYH+ + ++
Sbjct: 210 IIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYHVAIIQHMI 269
Query: 265 KAAAFSYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRIHK 324
K FS + C + +CL N DP IY A +++V R+ K
Sbjct: 270 KKLRFSNF-----LECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMRMLK 324
Query: 325 GWKEWSMKTDVTRL--THSRDTEELQ 348
S+ + V +SR+ E Q
Sbjct: 325 RQVSVSISSAVKSAPEENSREMTETQ 350
>gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo
sapiens]
Length = 337
Score = 110 bits (275), Expect = 2e-24
Identities = 68/283 (24%), Positives = 129/283 (45%), Gaps = 13/283 (4%)
Query: 45 LVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRN 104
L V+Y + +G P N + + ++ + +L LA +LLY +LP + Y +
Sbjct: 36 LPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYAS 95
Query: 105 QHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISA 164
W G CK + F N+Y SILFL C S R+ +++ + + R A++ A
Sbjct: 96 GENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACA 155
Query: 165 CIFI--LVGIVHYPVFQTEDKET----CFDMLQMD--SRIAGYYYARFTVGFAIPLSIIA 216
++I LV ++ T T C D+ D + I Y F +PL I+
Sbjct: 156 VVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFCLPLVIVT 215
Query: 217 FTNHRIFRSIKQSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDR 276
I ++ + + K K + I +++ F VCF P+H++ +++ +
Sbjct: 216 LCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIESRLL----- 270
Query: 277 NAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEV 319
+ C +E +++ A +V L+ +N + ++YV+ +D+ +Q V
Sbjct: 271 SISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAV 313
>gi|20544172 bradykinin receptor B1 [Homo sapiens]
Length = 353
Score = 110 bits (274), Expect = 3e-24
Identities = 83/312 (26%), Positives = 145/312 (46%), Gaps = 21/312 (6%)
Query: 29 SAKTCNNV--SFEESRIVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLAL 86
+A C+N +++ VL ++C G+ N + LL Q NV +YL LA
Sbjct: 22 NATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLLVFLLPRRQLNVAEIYLANLAA 81
Query: 87 CELLYTGTLPLWVIYIRNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVY 146
+L++ LP W I NQ W G L C+V + N+++SI + IS DR+ +V+
Sbjct: 82 SDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKANLFISIFLVVAISQDRYRVLVH 141
Query: 147 ALESRGRRRRRTAILISACIFILVGIVHYPVFQTEDKETCFDMLQMDSRI-----AGYYY 201
+ SR ++RRR A + I+++ G++ P F + D L + + I +++
Sbjct: 142 PMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQAVPD-LNITACILLLPHEAWHF 200
Query: 202 ARFT----VGFAIPLSIIAFTNHRIFRSIKQSMGLS-----AAQKAKVKHSAIAVVVIFL 252
AR +GF +PL+ I F N+ I S++ +S + +K + +VV FL
Sbjct: 201 ARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRCGGRKDSKTTALILTLVVAFL 260
Query: 253 VCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLAT 312
VC+APYH ++ ++ C E+ + + + N +P+IYV
Sbjct: 261 VCWAPYHFFAFLE----FLFQVQAVRGCFWEDFIDLGLQLANFFAFTNSSLNPVIYVFVG 316
Query: 313 DHSRQEVSRIHK 324
R +V ++K
Sbjct: 317 RLFRTKVWELYK 328
>gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens]
Length = 365
Score = 109 bits (273), Expect = 4e-24
Identities = 76/295 (25%), Positives = 137/295 (46%), Gaps = 15/295 (5%)
Query: 43 IVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYI 102
I+L V Y+ V LG+ N T WL + ++ + A Y+ LAL + LY +LP + Y
Sbjct: 36 ILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYY 95
Query: 103 RNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILI 162
+ W G CK ++F+ N+Y S+LFL CIS R++ + + L + R R A L+
Sbjct: 96 AAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLL 155
Query: 163 SACIFILVGIVHYP---VFQTEDKET---CFDMLQMDSRIAGYYYARFTVG--FAIPLSI 214
++++V P T +K T C D + + +++ +G F +P +
Sbjct: 156 CLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLV 215
Query: 215 IAFTNHRIFRSIKQSMGLSAAQKAKVK--HSAIAVVVIFLVCFAPYHLVLLVKAAAFSYY 272
+ R + Q + SA ++++ + V+ +F VCF P+H+ + Y
Sbjct: 216 TLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTI-----YYL 270
Query: 273 RGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRIHKGWK 327
A C + + V L++ N DP++Y+L D R+++ ++ G K
Sbjct: 271 ARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGK 325
>gi|14211849 putative purinergic receptor FKSG79 [Homo sapiens]
Length = 333
Score = 106 bits (265), Expect = 3e-23
Identities = 79/294 (26%), Positives = 130/294 (44%), Gaps = 25/294 (8%)
Query: 44 VLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIR 103
+ V Y+ + G+ N L W+ + + ++++ LA+ +LL +LPL + Y
Sbjct: 21 IYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYL 80
Query: 104 NQHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRG-RRRRRTAILI 162
N H W G C Y+ + N+Y SI FL CIS RF ++Y +++ I I
Sbjct: 81 N-HDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISI 139
Query: 163 SACIFILVGIVHYPVFQTED-----KETCFDMLQMDSRIAGYYYARFT----VGFAIPLS 213
+ + I + V +P+ +T D + CF L + T +GF PL
Sbjct: 140 AGWLIICLACVLFPLLRTSDDTSGNRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLL 199
Query: 214 IIAFTNHRIFRSI--KQSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYH----LVLLVKAA 267
I+ + + S+ K M +K K + +FL+CFAPYH L LVK+
Sbjct: 200 IVLYCTWKTVLSLQDKYPMAQDLGEKQKALKMILTCAGVFLICFAPYHFSFPLDFLVKS- 258
Query: 268 AFSYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSR 321
+ C + V LCL+++N DP+IY +T+ R+ +SR
Sbjct: 259 -------NEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFSTNEFRRRLSR 305
>gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens]
Length = 337
Score = 105 bits (263), Expect = 5e-23
Identities = 77/310 (24%), Positives = 143/310 (46%), Gaps = 14/310 (4%)
Query: 25 SLGLSAKTCNNVSFEESRIVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCL 84
+L +S+ TC++ + V +YS + +G N ++ + + + VY++ L
Sbjct: 6 NLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQVYMINL 65
Query: 85 ALCELLYTGTLPLWVIYIRNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAV 144
A+ +LL TLPL V+Y ++ W G C+++ Y + N+Y SI F+ +S R +A+
Sbjct: 66 AVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAI 125
Query: 145 VYALESRGRRRRRTAILISACIFILVGIVHYPVF----QTEDKET--CFDM---LQMDSR 195
V+ +++ ++ A + I+I V + P Q ++K CF+ Q +
Sbjct: 126 VFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQDNQTKNH 185
Query: 196 IAGYYYARFTVGFAIPLSIIAFTNHRIFRS-IKQSMGLSAAQKAKVKHSAIAVVVIFLVC 254
+ +Y VGF IP II I + +K+SM + + K + V FLV
Sbjct: 186 VLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHKKAIGMIMVVTAAFLVS 245
Query: 255 FAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDH 314
F PYH ++ ++ + C R+ + V+ L L+ N DP++Y + +
Sbjct: 246 FMPYH----IQRTIHLHFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGN 301
Query: 315 SRQEVSRIHK 324
R+ +S K
Sbjct: 302 FRKRLSTFRK 311
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.138 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,929,599
Number of Sequences: 37866
Number of extensions: 577970
Number of successful extensions: 2630
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 251
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 1897
Number of HSP's gapped (non-prelim): 439
length of query: 380
length of database: 18,247,518
effective HSP length: 104
effective length of query: 276
effective length of database: 14,309,454
effective search space: 3949409304
effective search space used: 3949409304
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.