Guide to the Human Genome
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Search of human proteins with 6912680

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6912680 meiotic recombination protein SPO11 isoform a [Homo
sapiens]
         (396 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6912680 meiotic recombination protein SPO11 isoform a [Homo s...   789   0.0  
gi|38201680 meiotic recombination protein SPO11 isoform b [Homo ...   698   0.0  
gi|50345988 ATP synthase, H+ transporting, mitochondrial F1 comp...    31   2.2  
gi|4885079 ATP synthase, H+ transporting, mitochondrial F1 compl...    31   2.2  
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi...    30   2.9  
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi...    30   2.9  

>gi|6912680 meiotic recombination protein SPO11 isoform a [Homo
           sapiens]
          Length = 396

 Score =  789 bits (2038), Expect = 0.0
 Identities = 396/396 (100%), Positives = 396/396 (100%)

Query: 1   MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASSSEVLASIENIIQDIIT 60
           MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASSSEVLASIENIIQDIIT
Sbjct: 1   MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASSSEVLASIENIIQDIIT 60

Query: 61  SLARNEAPAFTIDNRSSWENIKFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSM 120
           SLARNEAPAFTIDNRSSWENIKFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSM
Sbjct: 61  SLARNEAPAFTIDNRSSWENIKFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSM 120

Query: 121 IYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAG 180
           IYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAG
Sbjct: 121 IYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAG 180

Query: 181 NLRYIEEDGTKVNCTCGATAVAVPSNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNK 240
           NLRYIEEDGTKVNCTCGATAVAVPSNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNK
Sbjct: 181 NLRYIEEDGTKVNCTCGATAVAVPSNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNK 240

Query: 241 LSPCIMITGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEA 300
           LSPCIMITGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEA
Sbjct: 241 LSPCIMITGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEA 300

Query: 301 HHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEI 360
           HHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEI
Sbjct: 301 HHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEI 360

Query: 361 MADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI 396
           MADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI
Sbjct: 361 MADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI 396


>gi|38201680 meiotic recombination protein SPO11 isoform b [Homo
           sapiens]
          Length = 358

 Score =  698 bits (1801), Expect = 0.0
 Identities = 357/396 (90%), Positives = 358/396 (90%), Gaps = 38/396 (9%)

Query: 1   MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASSSEVLASIENIIQDIIT 60
           MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLAS                 
Sbjct: 1   MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLAS----------------- 43

Query: 61  SLARNEAPAFTIDNRSSWENIKFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSM 120
                                +FEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSM
Sbjct: 44  ---------------------RFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSM 82

Query: 121 IYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAG 180
           IYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAG
Sbjct: 83  IYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAG 142

Query: 181 NLRYIEEDGTKVNCTCGATAVAVPSNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNK 240
           NLRYIEEDGTKVNCTCGATAVAVPSNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNK
Sbjct: 143 NLRYIEEDGTKVNCTCGATAVAVPSNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNK 202

Query: 241 LSPCIMITGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEA 300
           LSPCIMITGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEA
Sbjct: 203 LSPCIMITGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEA 262

Query: 301 HHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEI 360
           HHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEI
Sbjct: 263 HHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEI 322

Query: 361 MADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI 396
           MADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI
Sbjct: 323 MADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI 358


>gi|50345988 ATP synthase, H+ transporting, mitochondrial F1
           complex, gamma subunit isoform L (liver) precursor [Homo
           sapiens]
          Length = 298

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 21/85 (24%), Positives = 39/85 (45%), Gaps = 10/85 (11%)

Query: 19  HRESLLAALRRGGREPPTGGSRLASSSEVLAS---------IENIIQDIITSLARNEAPA 69
           H +  L A +  GR+PPT G     + E+L S         I N  + +I S    E P 
Sbjct: 145 HSDQFLVAFKEVGRKPPTFGDASVIALELLNSGYEFDEGSIIFNKFRSVI-SYKTEEKPI 203

Query: 70  FTIDNRSSWENIKFEDSVGLQMVSH 94
           F+++  +S +++   D +   ++ +
Sbjct: 204 FSLNTVASADSMSIYDDIDADVLQN 228


>gi|4885079 ATP synthase, H+ transporting, mitochondrial F1 complex,
           gamma subunit isoform H (heart) precursor [Homo sapiens]
          Length = 297

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 21/85 (24%), Positives = 39/85 (45%), Gaps = 10/85 (11%)

Query: 19  HRESLLAALRRGGREPPTGGSRLASSSEVLAS---------IENIIQDIITSLARNEAPA 69
           H +  L A +  GR+PPT G     + E+L S         I N  + +I S    E P 
Sbjct: 145 HSDQFLVAFKEVGRKPPTFGDASVIALELLNSGYEFDEGSIIFNKFRSVI-SYKTEEKPI 203

Query: 70  FTIDNRSSWENIKFEDSVGLQMVSH 94
           F+++  +S +++   D +   ++ +
Sbjct: 204 FSLNTVASADSMSIYDDIDADVLQN 228


>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
           sapiens]
          Length = 847

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 7/108 (6%)

Query: 130 YATKRDIYYTDSQLFGNQTVVDNIIN--DISCMLKVSRRSLHILSTSKGLI-AGNLRYIE 186
           Y  K  +   D Q FG QT    IIN  D++  L    R+ ++ S  +  +    LR   
Sbjct: 319 YQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENTVDVEILRVTV 378

Query: 187 EDGTKVN-CTCGATAVAVPSNIQGIRNLVTDAKF---VLIVEKDATFQ 230
           ED   VN     A    +  N  G   +VTDAK    VL V K   ++
Sbjct: 379 EDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYE 426


>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
           sapiens]
          Length = 901

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 7/108 (6%)

Query: 130 YATKRDIYYTDSQLFGNQTVVDNIIN--DISCMLKVSRRSLHILSTSKGLI-AGNLRYIE 186
           Y  K  +   D Q FG QT    IIN  D++  L    R+ ++ S  +  +    LR   
Sbjct: 319 YQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENTVDVEILRVTV 378

Query: 187 EDGTKVN-CTCGATAVAVPSNIQGIRNLVTDAKF---VLIVEKDATFQ 230
           ED   VN     A    +  N  G   +VTDAK    VL V K   ++
Sbjct: 379 EDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYE 426


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,701,057
Number of Sequences: 37866
Number of extensions: 556034
Number of successful extensions: 1155
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1152
Number of HSP's gapped (non-prelim): 7
length of query: 396
length of database: 18,247,518
effective HSP length: 104
effective length of query: 292
effective length of database: 14,309,454
effective search space: 4178360568
effective search space used: 4178360568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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