Search of human proteins with 6912618

Search of human proteins with 6912618

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6912618 glutaminyl-peptide cyclotransferase precursor [Homo
sapiens]
         (361 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6912618 glutaminyl-peptide cyclotransferase precursor [Homo s...   741   0.0  
gi|92110027 glutaminyl-peptide cyclotransferase-like isoform 1 [...   315   3e-86
gi|254281335 glutaminyl-peptide cyclotransferase-like isoform 2 ...   200   2e-51
gi|55749804 aminopeptidase Fxna [Homo sapiens]                         38   0.016
gi|73486649 membrane-spanning 4-domains, subfamily A, member 3 i...    32   0.68 
gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens]             31   1.5  
gi|148806881 hypothetical protein LOC57608 [Homo sapiens]              30   3.4  
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ...    29   5.7  
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ...    29   5.7  
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]             29   5.7  
gi|122937396 coiled-coil domain containing 150 [Homo sapiens]          29   7.5  
gi|122937207 coiled-coil domain containing 61 [Homo sapiens]           28   9.8  

>gi|6912618 glutaminyl-peptide cyclotransferase precursor [Homo
           sapiens]
          Length = 361

 Score =  741 bits (1914), Expect = 0.0
 Identities = 361/361 (100%), Positives = 361/361 (100%)

Query: 1   MAGGRHRRVVGTLHLLLLVAALPWASRGVSPSASAWPEEKNYHQPAILNSSALRQIAEGT 60
           MAGGRHRRVVGTLHLLLLVAALPWASRGVSPSASAWPEEKNYHQPAILNSSALRQIAEGT
Sbjct: 1   MAGGRHRRVVGTLHLLLLVAALPWASRGVSPSASAWPEEKNYHQPAILNSSALRQIAEGT 60

Query: 61  SISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTPYGYRSF 120
           SISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTPYGYRSF
Sbjct: 61  SISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTPYGYRSF 120

Query: 121 SNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKLLS 180
           SNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKLLS
Sbjct: 121 SNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKLLS 180

Query: 181 LKTVSDSKPDLSLQLIFFDGEEAFLHWSPQDSLYGSRHLAAKMASTPHPPGARGTSQLHG 240
           LKTVSDSKPDLSLQLIFFDGEEAFLHWSPQDSLYGSRHLAAKMASTPHPPGARGTSQLHG
Sbjct: 181 LKTVSDSKPDLSLQLIFFDGEEAFLHWSPQDSLYGSRHLAAKMASTPHPPGARGTSQLHG 240

Query: 241 MDLLVLLDLIGAPNPTFPNFFPNSARWFERLQAIEHELHELGLLKDHSLEGRYFQNYSYG 300
           MDLLVLLDLIGAPNPTFPNFFPNSARWFERLQAIEHELHELGLLKDHSLEGRYFQNYSYG
Sbjct: 241 MDLLVLLDLIGAPNPTFPNFFPNSARWFERLQAIEHELHELGLLKDHSLEGRYFQNYSYG 300

Query: 301 GVIQDDHIPFLRRGVPVLHLIPSPFPEVWHTMDDNEENLDESTIDNLNKILQVFVLEYLH 360
           GVIQDDHIPFLRRGVPVLHLIPSPFPEVWHTMDDNEENLDESTIDNLNKILQVFVLEYLH
Sbjct: 301 GVIQDDHIPFLRRGVPVLHLIPSPFPEVWHTMDDNEENLDESTIDNLNKILQVFVLEYLH 360

Query: 361 L 361
           L
Sbjct: 361 L 361


>gi|92110027 glutaminyl-peptide cyclotransferase-like isoform 1
           [Homo sapiens]
          Length = 382

 Score =  315 bits (808), Expect = 3e-86
 Identities = 173/363 (47%), Positives = 222/363 (61%), Gaps = 15/363 (4%)

Query: 7   RRVVGTLHLLLLVAALPWASR------GVSPSASAWPEEKNYHQPAI--LNSSALRQIAE 58
           RR++  + LL L+ AL   S       G        P  +    P I  L  + LR++  
Sbjct: 27  RRLLPRVRLLPLLLALAVGSAFYTIWSGWHRRTEELPLGRELRVPLIGSLPEARLRRVVG 86

Query: 59  GTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTPYGYR 118
                 +W   L+PLL+ R PGSPG+   R+ +   ++ L A W +E+D F + TP G  
Sbjct: 87  QLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLEATLRSLTAGWHVELDPFTASTPLGPV 146

Query: 119 SFSNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKL 178
            F N+++TL+P A RHL LACHYDSK F    +  FVGATDSAVPCA++LELA+ALD   
Sbjct: 147 DFGNVVATLDPRAARHLTLACHYDSKLFPP-GSTPFVGATDSAVPCALLLELAQALD--- 202

Query: 179 LSLKTVSDSKPDLSLQLIFFDGEEAFLHWSPQDSLYGSRHLAAKMASTPHPPGARGTSQL 238
           L L         ++LQL+F DGEEA   W P+DSLYGSRHLA  M S PH PG    +++
Sbjct: 203 LELSRAKKQAAPVTLQLLFLDGEEALKEWGPKDSLYGSRHLAQLMESIPHSPGP---TRI 259

Query: 239 HGMDLLVLLDLIGAPNPTFPNFFPNSARWFERLQAIEHELHELGLLKDHSLEGRYFQNYS 298
             ++L +LLDL+GAPNPTF + FP + RWF RL++IE  LH L LL+ H  E  YFQ   
Sbjct: 260 QAIELFMLLDLLGAPNPTFYSHFPRTVRWFHRLRSIEKRLHRLNLLQSHPQEVMYFQPGE 319

Query: 299 YGGVIQDDHIPFLRRGVPVLHLIPSPFPEVWHTMDDNEENLDESTIDNLNKILQVFVLEY 358
             G ++DDHIPFLRRGVPVLHLI +PFP VWHT  D E NL   T+ NL +IL VF+ EY
Sbjct: 320 PFGSVEDDHIPFLRRGVPVLHLISTPFPAVWHTPADTEVNLHPPTVHNLCRILAVFLAEY 379

Query: 359 LHL 361
           L L
Sbjct: 380 LGL 382


>gi|254281335 glutaminyl-peptide cyclotransferase-like isoform 2
           [Homo sapiens]
          Length = 288

 Score =  200 bits (508), Expect = 2e-51
 Identities = 98/171 (57%), Positives = 120/171 (70%), Gaps = 3/171 (1%)

Query: 191 LSLQLIFFDGEEAFLHWSPQDSLYGSRHLAAKMASTPHPPGARGTSQLHGMDLLVLLDLI 250
           ++LQL+F DGEEA   W P+DSLYGSRHLA  M S PH PG    +++  ++L +LLDL+
Sbjct: 121 VTLQLLFLDGEEALKEWGPKDSLYGSRHLAQLMESIPHSPGP---TRIQAIELFMLLDLL 177

Query: 251 GAPNPTFPNFFPNSARWFERLQAIEHELHELGLLKDHSLEGRYFQNYSYGGVIQDDHIPF 310
           GAPNPTF + FP + RWF RL++IE  LH L LL+ H  E  YFQ     G ++DDHIPF
Sbjct: 178 GAPNPTFYSHFPRTVRWFHRLRSIEKRLHRLNLLQSHPQEVMYFQPGEPFGSVEDDHIPF 237

Query: 311 LRRGVPVLHLIPSPFPEVWHTMDDNEENLDESTIDNLNKILQVFVLEYLHL 361
           LRRGVPVLHLI +PFP VWHT  D E NL   T+ NL +IL VF+ EYL L
Sbjct: 238 LRRGVPVLHLISTPFPAVWHTPADTEVNLHPPTVHNLCRILAVFLAEYLGL 288



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 8/103 (7%)

Query: 7   RRVVGTLHLLLLVAALPWASR------GVSPSASAWPEEKNYHQPAI--LNSSALRQIAE 58
           RR++  + LL L+ AL   S       G        P  +    P I  L  + LR++  
Sbjct: 27  RRLLPRVRLLPLLLALAVGSAFYTIWSGWHRRTEELPLGRELRVPLIGSLPEARLRRVVG 86

Query: 59  GTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQRLQAD 101
                 +W   L+PLL+ R PGSPG+   R+     +Q L  D
Sbjct: 87  QLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKAAPVTLQLLFLD 129


>gi|55749804 aminopeptidase Fxna [Homo sapiens]
          Length = 904

 Score = 37.7 bits (86), Expect = 0.016
 Identities = 24/60 (40%), Positives = 34/60 (56%), Gaps = 9/60 (15%)

Query: 117 YRSFSNIISTLNPT-AKRHLVLA-CHYDSKYFSHWNNRVFVGATDSAVPCAMMLELARAL 174
           Y + +N++  L P    +H VLA CH+DS   S        GA+D AV C++MLE+ R L
Sbjct: 180 YDNITNVVVKLEPRDGAQHAVLANCHFDSVANSP-------GASDDAVSCSVMLEVLRVL 232


>gi|73486649 membrane-spanning 4-domains, subfamily A, member 3
           isoform a [Homo sapiens]
          Length = 214

 Score = 32.3 bits (72), Expect = 0.68
 Identities = 19/61 (31%), Positives = 27/61 (44%)

Query: 57  AEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTPYG 116
           A GT  SE    +L   + +   GSP    A+  ++  IQ L A  +L +  FL    Y 
Sbjct: 16  AHGTPGSEAGPEELNTSVYQPIDGSPDYQKAKLQVLGAIQILNAAMILALGVFLGSLQYP 75

Query: 117 Y 117
           Y
Sbjct: 76  Y 76


>gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens]
          Length = 643

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 37/154 (24%), Positives = 63/154 (40%), Gaps = 19/154 (12%)

Query: 215 GSRHLAAKMASTPHPPG--ARGTSQLHGMDLLVLLDLIGAPNPTFPNFFPNSARWF---- 268
           G+ H      S PH P   A   +Q  G D ++LL +  +  PT  + F  +  W     
Sbjct: 287 GTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELT 346

Query: 269 --------ERLQAIEHELHELGLLKDHSLEGRYFQNYSYGGVIQDDHIPFLRRGVPVLHL 320
                   ERL+ IE +      L++  L+ R  ++  +  V     +P L + +PV   
Sbjct: 347 SVYDSRARERLRQIEEQKALALQLQNQRLQER--EHSVHDSVELHLRVP-LEKEIPV--T 401

Query: 321 IPSPFPEVWHTMDDNEENLDESTIDNLNKILQVF 354
           +     +  H + D+E+   E T +   +I  VF
Sbjct: 402 VVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVF 435


>gi|148806881 hypothetical protein LOC57608 [Homo sapiens]
          Length = 1359

 Score = 30.0 bits (66), Expect = 3.4
 Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 5/63 (7%)

Query: 27  RGVSPSASAWPEEKNYHQPAILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYA 86
           RG SP     P+ + +     +  S + +   G S SE W  +LQP     +P SPG + 
Sbjct: 882 RGNSPEMRVEPQPRMW-----VPESPVCRSGRGESKSESWSEELQPGHPRAWPPSPGRFR 936

Query: 87  ARQ 89
             +
Sbjct: 937 VEE 939


>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
            sapiens]
          Length = 5033

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 38/169 (22%), Positives = 64/169 (37%), Gaps = 17/169 (10%)

Query: 71   QPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTPYGYRSFSNIISTLNPT 130
            Q  L    PG        + I++R+Q + A     +  +L QT + Y+S   +   L   
Sbjct: 3567 QMALYRGVPGREEDADDPEKIVRRVQEVSA-----VLYYLDQTEHPYKSKKAVWHKLLSK 3621

Query: 131  AKRHLVLAC-----------HYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKLL 179
             +R  V+AC           H     F       ++   D +    M+ +L++A +++  
Sbjct: 3622 QRRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGEQE-E 3680

Query: 180  SLKTVSDSKPDLSLQLIFFDGEEAFLHWSPQDSLYGSRHLAAKMASTPH 228
              + V + KPD   QL+      A    S  D  Y     A  MA + H
Sbjct: 3681 EEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCH 3729


>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
            sapiens]
          Length = 5038

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 38/169 (22%), Positives = 64/169 (37%), Gaps = 17/169 (10%)

Query: 71   QPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTPYGYRSFSNIISTLNPT 130
            Q  L    PG        + I++R+Q + A     +  +L QT + Y+S   +   L   
Sbjct: 3572 QMALYRGVPGREEDADDPEKIVRRVQEVSA-----VLYYLDQTEHPYKSKKAVWHKLLSK 3626

Query: 131  AKRHLVLAC-----------HYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKLL 179
             +R  V+AC           H     F       ++   D +    M+ +L++A +++  
Sbjct: 3627 QRRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGEQE-E 3685

Query: 180  SLKTVSDSKPDLSLQLIFFDGEEAFLHWSPQDSLYGSRHLAAKMASTPH 228
              + V + KPD   QL+      A    S  D  Y     A  MA + H
Sbjct: 3686 EEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCH 3734


>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
          Length = 363

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 8/61 (13%)

Query: 209 PQDSLYGSRHLAAKMAST--------PHPPGARGTSQLHGMDLLVLLDLIGAPNPTFPNF 260
           P D+ YG + LAA  A+         P P G R    L   +LL   + +  P P  P  
Sbjct: 111 PPDAFYGPQELAAAAAAAAATAARNNPEPGGRRPEGGLEADELLPAREKVAEPPPPPPPH 170

Query: 261 F 261
           F
Sbjct: 171 F 171


>gi|122937396 coiled-coil domain containing 150 [Homo sapiens]
          Length = 1101

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 14/36 (38%), Positives = 23/36 (63%)

Query: 263 NSARWFERLQAIEHELHELGLLKDHSLEGRYFQNYS 298
           N+A+  ER++ IE EL ++ L+KD   +  Y Q+ S
Sbjct: 908 NNAQNIERMKQIEKELKQMELIKDQYQKKNYEQSLS 943


>gi|122937207 coiled-coil domain containing 61 [Homo sapiens]
          Length = 531

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 19/68 (27%), Positives = 30/68 (44%)

Query: 51  SALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFL 110
           SAL Q +E  ++  +   DL+ L   +  G PGS A R   +   + L   + +E D   
Sbjct: 130 SALTQSSESVTLDLLTYTDLESLRNRKMGGRPGSLAPRSAQLNSKRYLILIYSVEFDRIH 189

Query: 111 SQTPYGYR 118
              P  Y+
Sbjct: 190 YPLPLPYQ 197


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,179,581
Number of Sequences: 37866
Number of extensions: 716846
Number of successful extensions: 1702
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1690
Number of HSP's gapped (non-prelim): 13
length of query: 361
length of database: 18,247,518
effective HSP length: 104
effective length of query: 257
effective length of database: 14,309,454
effective search space: 3677529678
effective search space used: 3677529678
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.