Guide to the Human Genome
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Search of human proteins with 6912420

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6912420 heparan sulfate 2-O-sulfotransferase 1 isoform 1
[Homo sapiens]
         (356 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6912420 heparan sulfate 2-O-sulfotransferase 1 isoform 1 [Hom...   728   0.0  
gi|197382758 heparan sulfate 2-O-sulfotransferase 1 isoform 2 [H...   474   e-134
gi|5032219 uronyl-2-sulfotransferase [Homo sapiens]                   148   8e-36
gi|8923758 carbohydrate sulfotransferase 11 [Homo sapiens]             35   0.13 
gi|4504831 potassium voltage-gated channel, subfamily H, member ...    30   3.3  
gi|27437001 potassium voltage-gated channel, subfamily H, member...    30   3.3  
gi|208431757 KLRAQ motif containing 1 isoform 3 [Homo sapiens]         30   3.3  
gi|24308420 KLRAQ motif containing 1 isoform 2 [Homo sapiens]          30   3.3  
gi|208431754 KLRAQ motif containing 1 isoform 1 [Homo sapiens]         30   3.3  
gi|32484977 angiomotin like 2 [Homo sapiens]                           30   3.3  
gi|89353783 coagulation factor II (thrombin) receptor-like 3 pre...    29   5.6  
gi|222537714 taxilin beta [Homo sapiens]                               28   9.6  

>gi|6912420 heparan sulfate 2-O-sulfotransferase 1 isoform 1 [Homo
           sapiens]
          Length = 356

 Score =  728 bits (1880), Expect = 0.0
 Identities = 356/356 (100%), Positives = 356/356 (100%)

Query: 1   MGLLRIMMPPKLQLLAVVAFAVAMLFLENQIQKLEESRSKLERAIARHEVREIEQRHTMD 60
           MGLLRIMMPPKLQLLAVVAFAVAMLFLENQIQKLEESRSKLERAIARHEVREIEQRHTMD
Sbjct: 1   MGLLRIMMPPKLQLLAVVAFAVAMLFLENQIQKLEESRSKLERAIARHEVREIEQRHTMD 60

Query: 61  GPRQDATLDEEEDMVIIYNRVPKTASTSFTNIAYDLCAKNKYHVLHINTTKNNPVMSLQD 120
           GPRQDATLDEEEDMVIIYNRVPKTASTSFTNIAYDLCAKNKYHVLHINTTKNNPVMSLQD
Sbjct: 61  GPRQDATLDEEEDMVIIYNRVPKTASTSFTNIAYDLCAKNKYHVLHINTTKNNPVMSLQD 120

Query: 121 QVRFVKNITSWKEMKPGFYHGHVSYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFG 180
           QVRFVKNITSWKEMKPGFYHGHVSYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFG
Sbjct: 121 QVRFVKNITSWKEMKPGFYHGHVSYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFG 180

Query: 181 DDYRPGLRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQA 240
           DDYRPGLRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQA
Sbjct: 181 DDYRPGLRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQA 240

Query: 241 KYNLINEYFLVGVTEELEDFIMLLEAALPRFFRGATELYRTGKKSHLRKTTEKKLPTKQT 300
           KYNLINEYFLVGVTEELEDFIMLLEAALPRFFRGATELYRTGKKSHLRKTTEKKLPTKQT
Sbjct: 241 KYNLINEYFLVGVTEELEDFIMLLEAALPRFFRGATELYRTGKKSHLRKTTEKKLPTKQT 300

Query: 301 IAKLQQSDIWKMENEFYEFALEQFQFIRAHAVREKDGDLYILAQNFFYEKIYPKSN 356
           IAKLQQSDIWKMENEFYEFALEQFQFIRAHAVREKDGDLYILAQNFFYEKIYPKSN
Sbjct: 301 IAKLQQSDIWKMENEFYEFALEQFQFIRAHAVREKDGDLYILAQNFFYEKIYPKSN 356


>gi|197382758 heparan sulfate 2-O-sulfotransferase 1 isoform 2 [Homo
           sapiens]
          Length = 229

 Score =  474 bits (1219), Expect = e-134
 Identities = 229/229 (100%), Positives = 229/229 (100%)

Query: 1   MGLLRIMMPPKLQLLAVVAFAVAMLFLENQIQKLEESRSKLERAIARHEVREIEQRHTMD 60
           MGLLRIMMPPKLQLLAVVAFAVAMLFLENQIQKLEESRSKLERAIARHEVREIEQRHTMD
Sbjct: 1   MGLLRIMMPPKLQLLAVVAFAVAMLFLENQIQKLEESRSKLERAIARHEVREIEQRHTMD 60

Query: 61  GPRQDATLDEEEDMVIIYNRVPKTASTSFTNIAYDLCAKNKYHVLHINTTKNNPVMSLQD 120
           GPRQDATLDEEEDMVIIYNRVPKTASTSFTNIAYDLCAKNKYHVLHINTTKNNPVMSLQD
Sbjct: 61  GPRQDATLDEEEDMVIIYNRVPKTASTSFTNIAYDLCAKNKYHVLHINTTKNNPVMSLQD 120

Query: 121 QVRFVKNITSWKEMKPGFYHGHVSYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFG 180
           QVRFVKNITSWKEMKPGFYHGHVSYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFG
Sbjct: 121 QVRFVKNITSWKEMKPGFYHGHVSYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFG 180

Query: 181 DDYRPGLRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECW 229
           DDYRPGLRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECW
Sbjct: 181 DDYRPGLRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECW 229


>gi|5032219 uronyl-2-sulfotransferase [Homo sapiens]
          Length = 406

 Score =  148 bits (373), Expect = 8e-36
 Identities = 85/265 (32%), Positives = 150/265 (56%), Gaps = 22/265 (8%)

Query: 76  IIYNRVPKTASTSFTNIAYDLCAKNKYHVLHINTTKNNPVMSLQDQVRFVKNITSWKEMK 135
           ++YNRV K  S +   +   L  K+ ++++  +   N   ++  +Q+  +KNI++ ++  
Sbjct: 105 VVYNRVGKCGSRTVVLLLRILSEKHGFNLV-TSDIHNKTRLTKNEQMELIKNISTAEQ-- 161

Query: 136 PGFYHGHVSYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFGDDYR---------PG 186
           P  +  HV +L+F++FG   +P+YIN+IRDP+ R +S Y+F RFGD +R         P 
Sbjct: 162 PYLFTRHVHFLNFSRFG-GDQPVYINIIRDPVNRFLSNYFFRRFGD-WRGEQNHMIRTPS 219

Query: 187 LRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQAKYNLIN 246
           +R+ ++      +EC+ E   +C+  +L+  IP+FCG    C   G  WA+++AK N+  
Sbjct: 220 MRQEER--YLDINECILENYPECSNPRLFYIIPYFCGQHPRCREPGE-WALERAKLNVNE 276

Query: 247 EYFLVGVTEELEDFIMLLEAALPRFFRGATELYRT---GKKSHLRKTTEKKLPTKQTIAK 303
            + LVG+ EELED ++LLE  LP +F+G   +Y+     K  ++  T +K +P+ + +  
Sbjct: 277 NFLLVGILEELEDVLLLLERFLPHYFKGVLSIYKDPEHRKLGNMTVTVKKTVPSPEAVQI 336

Query: 304 LQQSDIWKMENEFYEFALEQFQFIR 328
           L Q    + E EFY +  EQF  ++
Sbjct: 337 LYQR--MRYEYEFYHYVKEQFHLLK 359


>gi|8923758 carbohydrate sulfotransferase 11 [Homo sapiens]
          Length = 352

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 37/151 (24%), Positives = 60/151 (39%), Gaps = 39/151 (25%)

Query: 71  EEDMVIIYNRVPKTASTSFTNIAYDLCAKNKYHVLHINTTKNNPVMSLQDQVRFVKNITS 130
           +ED  +IY  VPK A T++  +   L  + KY         ++P+    ++     N+ +
Sbjct: 113 DEDHELIYCYVPKVACTNWKRLMMVLTGRGKY---------SDPMEIPANEAHVSANLKT 163

Query: 131 WKEMK-PGFYHGHVSYLDFAKFGVKKKPIYINVIRDPIERLVSYY-------YFLRFGDD 182
             +   P   H   SY+ F              +R+P ERLVS Y       Y + F   
Sbjct: 164 LNQYSIPEINHRLKSYMKFL------------FVREPFERLVSAYRNKFTQKYNISFHKR 211

Query: 183 YRPGLRRR----------KQGDKKTFDECVA 203
           Y   + +R          ++GD   F+E VA
Sbjct: 212 YGTKIIKRQRKNATQEALRKGDDVKFEEFVA 242


>gi|4504831 potassium voltage-gated channel, subfamily H, member 1
           isoform 2 [Homo sapiens]
          Length = 962

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 3/37 (8%)

Query: 200 ECVAE--GGSDCAPEKLWLQIPFFCGHSSECWNVGSR 234
           EC+    GG DCA  K W +    CG  SE WN  S+
Sbjct: 793 ECLGPKGGGGDCAKRKSWARFKDACG-KSEDWNKVSK 828


>gi|27437001 potassium voltage-gated channel, subfamily H, member 1
           isoform 1 [Homo sapiens]
          Length = 989

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 3/37 (8%)

Query: 200 ECVAE--GGSDCAPEKLWLQIPFFCGHSSECWNVGSR 234
           EC+    GG DCA  K W +    CG  SE WN  S+
Sbjct: 820 ECLGPKGGGGDCAKRKSWARFKDACG-KSEDWNKVSK 855


>gi|208431757 KLRAQ motif containing 1 isoform 3 [Homo sapiens]
          Length = 734

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 25/109 (22%), Positives = 45/109 (41%)

Query: 27  LENQIQKLEESRSKLERAIARHEVREIEQRHTMDGPRQDATLDEEEDMVIIYNRVPKTAS 86
           L+N   KLE     LE+      +R  E +  +    +D +   EE + II  +VP   +
Sbjct: 126 LQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDT 185

Query: 87  TSFTNIAYDLCAKNKYHVLHINTTKNNPVMSLQDQVRFVKNITSWKEMK 135
                 A ++   N+ H L +       +  +QD V  + N  ++ E +
Sbjct: 186 KYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQR 234


>gi|24308420 KLRAQ motif containing 1 isoform 2 [Homo sapiens]
          Length = 769

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 25/109 (22%), Positives = 45/109 (41%)

Query: 27  LENQIQKLEESRSKLERAIARHEVREIEQRHTMDGPRQDATLDEEEDMVIIYNRVPKTAS 86
           L+N   KLE     LE+      +R  E +  +    +D +   EE + II  +VP   +
Sbjct: 172 LQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDT 231

Query: 87  TSFTNIAYDLCAKNKYHVLHINTTKNNPVMSLQDQVRFVKNITSWKEMK 135
                 A ++   N+ H L +       +  +QD V  + N  ++ E +
Sbjct: 232 KYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQR 280


>gi|208431754 KLRAQ motif containing 1 isoform 1 [Homo sapiens]
          Length = 780

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 25/109 (22%), Positives = 45/109 (41%)

Query: 27  LENQIQKLEESRSKLERAIARHEVREIEQRHTMDGPRQDATLDEEEDMVIIYNRVPKTAS 86
           L+N   KLE     LE+      +R  E +  +    +D +   EE + II  +VP   +
Sbjct: 172 LQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDT 231

Query: 87  TSFTNIAYDLCAKNKYHVLHINTTKNNPVMSLQDQVRFVKNITSWKEMK 135
                 A ++   N+ H L +       +  +QD V  + N  ++ E +
Sbjct: 232 KYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQR 280


>gi|32484977 angiomotin like 2 [Homo sapiens]
          Length = 780

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 14/34 (41%), Positives = 21/34 (61%)

Query: 27  LENQIQKLEESRSKLERAIARHEVREIEQRHTMD 60
           LE++IQ+L E+   L RA ++ E  E   R+ MD
Sbjct: 348 LESEIQRLSEAHESLTRASSKREALEKTMRNKMD 381


>gi|89353783 coagulation factor II (thrombin) receptor-like 3
           precursor [Homo sapiens]
          Length = 385

 Score = 29.3 bits (64), Expect = 5.6
 Identities = 16/57 (28%), Positives = 26/57 (45%), Gaps = 1/57 (1%)

Query: 151 FGVKKKPIYINVIRDPIERLVSYYYFLRFGDDYRPGLRRRKQGDKKTFDECVAEGGS 207
           +G     + ++ +   ++  + YY    F D  R GL +R  GD     +  AEGGS
Sbjct: 319 YGAYVPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGD-TVASKASAEGGS 374


>gi|222537714 taxilin beta [Homo sapiens]
          Length = 684

 Score = 28.5 bits (62), Expect = 9.6
 Identities = 19/74 (25%), Positives = 38/74 (51%), Gaps = 3/74 (4%)

Query: 3   LLRIMMPPKLQLLAVVAFAVAMLFLENQIQKLEESRSKLERAIARHEVREIE---QRHTM 59
           LL ++    L+      F + +  LEN  + L+E R++L + I   E+ E +   Q ++ 
Sbjct: 416 LLDMIEEKALRAKEYECFVMKIGRLENLCRALQEERNELHKKIRDAEISEKDDQSQHNSD 475

Query: 60  DGPRQDATLDEEED 73
           + P  + ++D+E D
Sbjct: 476 EEPESNVSVDQEID 489


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,491,351
Number of Sequences: 37866
Number of extensions: 581710
Number of successful extensions: 1580
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1568
Number of HSP's gapped (non-prelim): 13
length of query: 356
length of database: 18,247,518
effective HSP length: 103
effective length of query: 253
effective length of database: 14,347,320
effective search space: 3629871960
effective search space used: 3629871960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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