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Search of human proteins with 68303549
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|68303549 argininosuccinate lyase isoform 3 [Homo sapiens]
(438 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|68303549 argininosuccinate lyase isoform 3 [Homo sapiens] 872 0.0
gi|31541964 argininosuccinate lyase isoform 1 [Homo sapiens] 858 0.0
gi|68303542 argininosuccinate lyase isoform 1 [Homo sapiens] 858 0.0
gi|68303547 argininosuccinate lyase isoform 2 [Homo sapiens] 805 0.0
gi|95089461 discs large homolog 5 [Homo sapiens] 33 0.67
gi|239754171 PREDICTED: chromosome 5 open reading frame 50 [Homo... 31 1.9
gi|169168128 PREDICTED: chromosome 5 open reading frame 50 [Homo... 31 1.9
gi|239742721 PREDICTED: chromosome 5 open reading frame 50 [Homo... 31 1.9
gi|111548650 family with sequence similarity 170, member A [Homo... 31 2.5
gi|212549536 regulator of G-protein signaling like 1 [Homo sapiens] 29 9.6
>gi|68303549 argininosuccinate lyase isoform 3 [Homo sapiens]
Length = 438
Score = 872 bits (2253), Expect = 0.0
Identities = 438/438 (100%), Positives = 438/438 (100%)
Query: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM
Sbjct: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
Query: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD
Sbjct: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
Query: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSGAIAG 180
LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSGAIAG
Sbjct: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSGAIAG 180
Query: 181 NPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTK 240
NPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTK
Sbjct: 181 NPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTK 240
Query: 241 EFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQ 300
EFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQ
Sbjct: 241 EFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQ 300
Query: 301 EDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRKGMPFRQ 360
EDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRKGMPFRQ
Sbjct: 301 EDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRKGMPFRQ 360
Query: 361 AHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGALGGTARS 420
AHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGALGGTARS
Sbjct: 361 AHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGALGGTARS 420
Query: 421 SVDWQIRQVRALLQAQQA 438
SVDWQIRQVRALLQAQQA
Sbjct: 421 SVDWQIRQVRALLQAQQA 438
>gi|31541964 argininosuccinate lyase isoform 1 [Homo sapiens]
Length = 464
Score = 858 bits (2216), Expect = 0.0
Identities = 438/464 (94%), Positives = 438/464 (94%), Gaps = 26/464 (5%)
Query: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM
Sbjct: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
Query: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD
Sbjct: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
Query: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILS----- 175
LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILS
Sbjct: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL 180
Query: 176 ---------------------GAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 214
GAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA
Sbjct: 181 TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 240
Query: 215 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 274
EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA
Sbjct: 241 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 300
Query: 275 GRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM 334
GRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM
Sbjct: 301 GRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM 360
Query: 335 GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF 394
GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF
Sbjct: 361 GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF 420
Query: 395 SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA 438
SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA
Sbjct: 421 SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA 464
>gi|68303542 argininosuccinate lyase isoform 1 [Homo sapiens]
Length = 464
Score = 858 bits (2216), Expect = 0.0
Identities = 438/464 (94%), Positives = 438/464 (94%), Gaps = 26/464 (5%)
Query: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM
Sbjct: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
Query: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD
Sbjct: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
Query: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILS----- 175
LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILS
Sbjct: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL 180
Query: 176 ---------------------GAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 214
GAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA
Sbjct: 181 TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 240
Query: 215 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 274
EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA
Sbjct: 241 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 300
Query: 275 GRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM 334
GRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM
Sbjct: 301 GRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM 360
Query: 335 GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF 394
GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF
Sbjct: 361 GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF 420
Query: 395 SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA 438
SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA
Sbjct: 421 SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA 464
>gi|68303547 argininosuccinate lyase isoform 2 [Homo sapiens]
Length = 444
Score = 805 bits (2080), Expect = 0.0
Identities = 418/464 (90%), Positives = 418/464 (90%), Gaps = 46/464 (9%)
Query: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM
Sbjct: 1 MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEM 60
Query: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD
Sbjct: 61 DQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTD 120
Query: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWIL------ 174
LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWIL
Sbjct: 121 LRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL 180
Query: 175 --------------------SGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 214
SGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA
Sbjct: 181 TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVA 240
Query: 215 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 274
EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA
Sbjct: 241 EFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA 300
Query: 275 GRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM 334
GRVFGR EDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM
Sbjct: 301 GRVFGR--------------------EDKEAVFEVSDTMSAVLQVATGVISTLQIHQENM 340
Query: 335 GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF 394
GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF
Sbjct: 341 GQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF 400
Query: 395 SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA 438
SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA
Sbjct: 401 SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA 444
>gi|95089461 discs large homolog 5 [Homo sapiens]
Length = 1919
Score = 32.7 bits (73), Expect = 0.67
Identities = 31/106 (29%), Positives = 45/106 (42%), Gaps = 17/106 (16%)
Query: 55 LTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANE-----RRLKELIGATAGKLHT 109
L +E DQ++ LDK+ E KL S+ + ANE R++K+ + AG
Sbjct: 434 LIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAG---- 489
Query: 110 GRSRNDQVVTDLRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLF 155
R ++ V LR + C L L E D A+ RD F
Sbjct: 490 ---RANKEVEILRKQCKALCQELKEALQE-----ADVAKCRRDWAF 527
>gi|239754171 PREDICTED: chromosome 5 open reading frame 50 [Homo
sapiens]
Length = 371
Score = 31.2 bits (69), Expect = 1.9
Identities = 27/107 (25%), Positives = 42/107 (39%), Gaps = 14/107 (13%)
Query: 79 FKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWM---------RQTC 129
++ N E+ LKE + + KL + +Q+ DL LW+ + C
Sbjct: 218 YQTNEPSEEPIKTIRNWLKEKLHVFSEKLEEEVQQLEQLAWDLELWLDALLGEPHQEEHC 277
Query: 130 STLSGLLWE----LIRTMVD-RAEAERDVLFPGYTHLQRAQPIRWSH 171
ST LWE L R D E+ + P T + ++Q W H
Sbjct: 278 STYKSHLWEWAWALGREHKDFPVESGKRAELPAQTDMSQSQGSSWKH 324
>gi|169168128 PREDICTED: chromosome 5 open reading frame 50 [Homo
sapiens]
Length = 371
Score = 31.2 bits (69), Expect = 1.9
Identities = 27/107 (25%), Positives = 42/107 (39%), Gaps = 14/107 (13%)
Query: 79 FKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWM---------RQTC 129
++ N E+ LKE + + KL + +Q+ DL LW+ + C
Sbjct: 218 YQTNEPSEEPIKTIRNWLKEKLHVFSEKLEEEVQQLEQLAWDLELWLDALLGEPHQEEHC 277
Query: 130 STLSGLLWE----LIRTMVD-RAEAERDVLFPGYTHLQRAQPIRWSH 171
ST LWE L R D E+ + P T + ++Q W H
Sbjct: 278 STYKSHLWEWAWALGREHKDFPVESGKRAELPAQTDMSQSQGSSWKH 324
>gi|239742721 PREDICTED: chromosome 5 open reading frame 50 [Homo
sapiens]
Length = 371
Score = 31.2 bits (69), Expect = 1.9
Identities = 27/107 (25%), Positives = 42/107 (39%), Gaps = 14/107 (13%)
Query: 79 FKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWM---------RQTC 129
++ N E+ LKE + + KL + +Q+ DL LW+ + C
Sbjct: 218 YQTNEPSEEPIKTIRNWLKEKLHVFSEKLEEEVQQLEQLAWDLELWLDALLGEPHQEEHC 277
Query: 130 STLSGLLWE----LIRTMVD-RAEAERDVLFPGYTHLQRAQPIRWSH 171
ST LWE L R D E+ + P T + ++Q W H
Sbjct: 278 STYKSHLWEWAWALGREHKDFPVESGKRAELPAQTDMSQSQGSSWKH 324
>gi|111548650 family with sequence similarity 170, member A [Homo
sapiens]
Length = 329
Score = 30.8 bits (68), Expect = 2.5
Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 50 EKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLH 108
EK G ++K++ D + G +VA+ W+QG ++ S E + R +LI + ++H
Sbjct: 20 EKGGGMSKSQEDALQPGSTRVAKGWSQGVGEVTSTSEYCSCVSSSR--KLIHSGIQRIH 76
>gi|212549536 regulator of G-protein signaling like 1 [Homo sapiens]
Length = 1076
Score = 28.9 bits (63), Expect = 9.6
Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
Query: 234 LILYCTKEFSFVQLSDAYST--GSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTL-KG 290
+++Y K F F + + +Y G +K P S + +G G A L TL +G
Sbjct: 971 VVMYFWKRFCFWKATRSYLQYRGKKFKDRKSPPKSTDKYPFSSG---GDNAILRFTLLRG 1027
Query: 291 LPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALS 339
+ + LQ +EA+ V ++ S+ L V+S +Q+H GQ LS
Sbjct: 1028 I-----EWLQPQREAISSVQNSSSSKLTQPRLVVSAMQLHPV-QGQKLS 1070
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,989,410
Number of Sequences: 37866
Number of extensions: 602582
Number of successful extensions: 1299
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1290
Number of HSP's gapped (non-prelim): 10
length of query: 438
length of database: 18,247,518
effective HSP length: 105
effective length of query: 333
effective length of database: 14,271,588
effective search space: 4752438804
effective search space used: 4752438804
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.