Guide to the Human Genome
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Search of human proteins with 66346715

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|66346715 mature T-cell proliferation 1 [Homo sapiens]
         (107 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|66346715 mature T-cell proliferation 1 [Homo sapiens]              225   5e-60
gi|148922879 T-cell leukemia/lymphoma 1A [Homo sapiens]                89   8e-19
gi|11415028 T-cell leukemia/lymphoma 1A [Homo sapiens]                 89   8e-19
gi|40548375 T-cell leukemia/lymphoma 1B [Homo sapiens]                 67   3e-12
gi|4759220 T-cell leukemia/lymphoma 1B [Homo sapiens]                  67   3e-12
gi|31742498 unc-84 homolog B [Homo sapiens]                            32   0.11 
gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens]               30   0.55 
gi|148922852 general transcription factor IIH, polypeptide 2C [H...    26   7.9  
gi|148922900 general transcription factor IIH, polypeptide 2B [H...    26   7.9  
gi|42518080 transcription factor 7 (T-cell specific, HMG-box) is...    26   7.9  
gi|6681762 general transcription factor IIH, polypeptide 2, 44kD...    26   7.9  
gi|109809737 general transcription factor IIH, polypeptide 2D [H...    26   7.9  

>gi|66346715 mature T-cell proliferation 1 [Homo sapiens]
          Length = 107

 Score =  225 bits (574), Expect = 5e-60
 Identities = 107/107 (100%), Positives = 107/107 (100%)

Query: 1   MAGEDVGAPPDHLWVHQEGIYRDEYQRTWVAVVEEETSFLRARVQQIQVPLGDAARPSHL 60
           MAGEDVGAPPDHLWVHQEGIYRDEYQRTWVAVVEEETSFLRARVQQIQVPLGDAARPSHL
Sbjct: 1   MAGEDVGAPPDHLWVHQEGIYRDEYQRTWVAVVEEETSFLRARVQQIQVPLGDAARPSHL 60

Query: 61  LTSQLPLMWQLYPEERYMDNNSRLWQIQHHLMVRGVQELLLKLLPDD 107
           LTSQLPLMWQLYPEERYMDNNSRLWQIQHHLMVRGVQELLLKLLPDD
Sbjct: 61  LTSQLPLMWQLYPEERYMDNNSRLWQIQHHLMVRGVQELLLKLLPDD 107


>gi|148922879 T-cell leukemia/lymphoma 1A [Homo sapiens]
          Length = 114

 Score = 89.0 bits (219), Expect = 8e-19
 Identities = 43/107 (40%), Positives = 66/107 (61%), Gaps = 2/107 (1%)

Query: 3   GEDVGAPPDHLWVHQEGIYRDEYQRTWVAVVEEETSFLRARV--QQIQVPLGDAARPSHL 60
           GE V   PD LW  ++ +Y DE Q  W+ +  E    L+ RV  ++  V LG    P+ +
Sbjct: 8   GEAVTDHPDRLWAWEKFVYLDEKQHAWLPLTIEIKDRLQLRVLLRREDVVLGRPMTPTQI 67

Query: 61  LTSQLPLMWQLYPEERYMDNNSRLWQIQHHLMVRGVQELLLKLLPDD 107
             S LP+MWQLYP+ RY  ++S  W++ +H+ + GV+++LL+LLPDD
Sbjct: 68  GPSLLPIMWQLYPDGRYRSSDSSFWRLVYHIKIDGVEDMLLELLPDD 114


>gi|11415028 T-cell leukemia/lymphoma 1A [Homo sapiens]
          Length = 114

 Score = 89.0 bits (219), Expect = 8e-19
 Identities = 43/107 (40%), Positives = 66/107 (61%), Gaps = 2/107 (1%)

Query: 3   GEDVGAPPDHLWVHQEGIYRDEYQRTWVAVVEEETSFLRARV--QQIQVPLGDAARPSHL 60
           GE V   PD LW  ++ +Y DE Q  W+ +  E    L+ RV  ++  V LG    P+ +
Sbjct: 8   GEAVTDHPDRLWAWEKFVYLDEKQHAWLPLTIEIKDRLQLRVLLRREDVVLGRPMTPTQI 67

Query: 61  LTSQLPLMWQLYPEERYMDNNSRLWQIQHHLMVRGVQELLLKLLPDD 107
             S LP+MWQLYP+ RY  ++S  W++ +H+ + GV+++LL+LLPDD
Sbjct: 68  GPSLLPIMWQLYPDGRYRSSDSSFWRLVYHIKIDGVEDMLLELLPDD 114


>gi|40548375 T-cell leukemia/lymphoma 1B [Homo sapiens]
          Length = 128

 Score = 67.0 bits (162), Expect = 3e-12
 Identities = 40/120 (33%), Positives = 57/120 (47%), Gaps = 22/120 (18%)

Query: 6   VGAPPDHLWVHQEGIYRDEYQRTWVAVVEEETSFLRARVQQIQVPLGDAARPS------- 58
           +G PP  LW+ + GIY DE  RTWV VV     F  +R +  +   G    PS       
Sbjct: 9   LGVPPGRLWIQRPGIYEDEEGRTWVTVV---VRFNPSRREWARASQGSRYEPSITVHLWQ 65

Query: 59  ------HLLTS------QLPLMWQLYPEERYMDNNSRLWQIQHHLMVRGVQELLLKLLPD 106
                  LL+S      QLP +WQLYP  +Y   +S  W+I  H  +  +++L+L   P+
Sbjct: 66  MAVHTRELLSSGQMPFSQLPAVWQLYPGRKYRAADSSFWEIADHGQIDSMEQLVLTYQPE 125


>gi|4759220 T-cell leukemia/lymphoma 1B [Homo sapiens]
          Length = 128

 Score = 67.0 bits (162), Expect = 3e-12
 Identities = 40/120 (33%), Positives = 57/120 (47%), Gaps = 22/120 (18%)

Query: 6   VGAPPDHLWVHQEGIYRDEYQRTWVAVVEEETSFLRARVQQIQVPLGDAARPS------- 58
           +G PP  LW+ + GIY DE  RTWV VV     F  +R +  +   G    PS       
Sbjct: 9   LGVPPGRLWIQRPGIYEDEEGRTWVTVV---VRFNPSRREWARASQGSRYEPSITVHLWQ 65

Query: 59  ------HLLTS------QLPLMWQLYPEERYMDNNSRLWQIQHHLMVRGVQELLLKLLPD 106
                  LL+S      QLP +WQLYP  +Y   +S  W+I  H  +  +++L+L   P+
Sbjct: 66  MAVHTRELLSSGQMPFSQLPAVWQLYPGRKYRAADSSFWEIADHGQIDSMEQLVLTYQPE 125


>gi|31742498 unc-84 homolog B [Homo sapiens]
          Length = 717

 Score = 32.0 bits (71), Expect = 0.11
 Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 1   MAGEDVGAPPDHLWVHQEGIYRDEYQRTWVAVVEEETSFLRARVQQIQVPLGD----AAR 56
           ++ ED  A  + L   +E   +++++R   A ++EE S LRA  QQ    L      A++
Sbjct: 323 LSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQ 382

Query: 57  PSHLLTSQLPLMWQLYPEERYMDNN 81
            S     QL   WQ   +E + +++
Sbjct: 383 ESEARIQQLKSEWQSMTQESFQESS 407


>gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens]
          Length = 663

 Score = 29.6 bits (65), Expect = 0.55
 Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 1/58 (1%)

Query: 35  EETSFLRARVQQIQVPLGDAARPSHLLTSQLPLMWQLYPEERYMDNNSRLWQIQHHLM 92
           E    L+  V QIQ P   +  P+  L S  PL W L  +    +++ +L +IQ+HL+
Sbjct: 306 EPNGKLQPMVIQIQPPNPSSPTPTLFLPSDPPLAW-LLAKSWVRNSDFQLHEIQYHLL 362


>gi|148922852 general transcription factor IIH, polypeptide 2C
          [Homo sapiens]
          Length = 395

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 9/23 (39%), Positives = 16/23 (69%)

Query: 25 YQRTWVAVVEEETSFLRARVQQI 47
          Y+RTW  + E+E+  L+A ++ I
Sbjct: 15 YERTWEILKEDESGSLKATIEDI 37


>gi|148922900 general transcription factor IIH, polypeptide 2B
          [Homo sapiens]
          Length = 395

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 9/23 (39%), Positives = 16/23 (69%)

Query: 25 YQRTWVAVVEEETSFLRARVQQI 47
          Y+RTW  + E+E+  L+A ++ I
Sbjct: 15 YERTWEILKEDESGSLKATIEDI 37


>gi|42518080 transcription factor 7 (T-cell specific, HMG-box)
          isoform 1 [Homo sapiens]
          Length = 384

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 1/56 (1%)

Query: 3  GEDVGAPPDHLWVHQEGIYRDEYQRTWVAVVEEETSFLRAR-VQQIQVPLGDAARP 57
          G+D+GAP + L    EG  +D+  R   A  E + + L++  V + +   G A  P
Sbjct: 14 GDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESEGAAGGAGIP 69


>gi|6681762 general transcription factor IIH, polypeptide 2, 44kD
          subunit [Homo sapiens]
          Length = 395

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 9/23 (39%), Positives = 16/23 (69%)

Query: 25 YQRTWVAVVEEETSFLRARVQQI 47
          Y+RTW  + E+E+  L+A ++ I
Sbjct: 15 YERTWEILKEDESGSLKATIEDI 37


>gi|109809737 general transcription factor IIH, polypeptide 2D
          [Homo sapiens]
          Length = 395

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 9/23 (39%), Positives = 16/23 (69%)

Query: 25 YQRTWVAVVEEETSFLRARVQQI 47
          Y+RTW  + E+E+  L+A ++ I
Sbjct: 15 YERTWEILKEDESGSLKATIEDI 37


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,612,123
Number of Sequences: 37866
Number of extensions: 174314
Number of successful extensions: 391
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 377
Number of HSP's gapped (non-prelim): 12
length of query: 107
length of database: 18,247,518
effective HSP length: 77
effective length of query: 30
effective length of database: 15,331,836
effective search space: 459955080
effective search space used: 459955080
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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