Guide to the Human Genome
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Search of human proteins with 66346698

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|66346698 alpha-N-acetylglucosaminidase precursor [Homo
sapiens]
         (743 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|66346698 alpha-N-acetylglucosaminidase precursor [Homo sapiens]   1521   0.0  
gi|160948610 E3 ubiquitin-protein ligase UBR3 [Homo sapiens]           32   1.6  
gi|46049110 myosin binding protein C, slow type isoform 4 [Homo ...    32   2.1  
gi|46049119 myosin binding protein C, slow type isoform 3 [Homo ...    32   2.1  
gi|46049125 myosin binding protein C, slow type isoform 2 [Homo ...    32   2.1  
gi|45976288 myosin binding protein C, slow type isoform 1 [Homo ...    32   2.1  
gi|19923957 major facilitator superfamily domain containing 3 [H...    32   2.1  
gi|5902108 SRY-box 21 [Homo sapiens]                                   31   3.6  
gi|31543093 galactosidase, beta 1-like 2 [Homo sapiens]                30   6.2  
gi|20162554 Kruppel-like factor 14 [Homo sapiens]                      30   6.2  
gi|4507013 solute carrier family 2 (facilitated glucose/fructose...    30   6.2  
gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens]        30   6.2  
gi|206725452 leukocyte receptor cluster (LRC) member 9 [Homo sap...    30   6.2  
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            30   8.1  

>gi|66346698 alpha-N-acetylglucosaminidase precursor [Homo sapiens]
          Length = 743

 Score = 1521 bits (3938), Expect = 0.0
 Identities = 743/743 (100%), Positives = 743/743 (100%)

Query: 1   MEAVAVAAAVGVLLLAGAGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVERALAAKP 60
           MEAVAVAAAVGVLLLAGAGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVERALAAKP
Sbjct: 1   MEAVAVAAAVGVLLLAGAGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVERALAAKP 60

Query: 61  GLDTYSLGGGGAARVRVRGSTGVAAAAGLHRYLRDFCGCHVAWSGSQLRLPRPLPAVPGE 120
           GLDTYSLGGGGAARVRVRGSTGVAAAAGLHRYLRDFCGCHVAWSGSQLRLPRPLPAVPGE
Sbjct: 61  GLDTYSLGGGGAARVRVRGSTGVAAAAGLHRYLRDFCGCHVAWSGSQLRLPRPLPAVPGE 120

Query: 121 LTEATPNRYRYYQNVCTQSYSFVWWDWARWEREIDWMALNGINLALAWSGQEAIWQRVYL 180
           LTEATPNRYRYYQNVCTQSYSFVWWDWARWEREIDWMALNGINLALAWSGQEAIWQRVYL
Sbjct: 121 LTEATPNRYRYYQNVCTQSYSFVWWDWARWEREIDWMALNGINLALAWSGQEAIWQRVYL 180

Query: 181 ALGLTQAEINEFFTGPAFLAWGRMGNLHTWDGPLPPSWHIKQLYLQHRVLDQMRSFGMTP 240
           ALGLTQAEINEFFTGPAFLAWGRMGNLHTWDGPLPPSWHIKQLYLQHRVLDQMRSFGMTP
Sbjct: 181 ALGLTQAEINEFFTGPAFLAWGRMGNLHTWDGPLPPSWHIKQLYLQHRVLDQMRSFGMTP 240

Query: 241 VLPAFAGHVPEAVTRVFPQVNVTKMGSWGHFNCSYSCSFLLAPEDPIFPIIGSLFLRELI 300
           VLPAFAGHVPEAVTRVFPQVNVTKMGSWGHFNCSYSCSFLLAPEDPIFPIIGSLFLRELI
Sbjct: 241 VLPAFAGHVPEAVTRVFPQVNVTKMGSWGHFNCSYSCSFLLAPEDPIFPIIGSLFLRELI 300

Query: 301 KEFGTDHIYGADTFNEMQPPSSEPSYLAAATTAVYEAMTAVDTEAVWLLQGWLFQHQPQF 360
           KEFGTDHIYGADTFNEMQPPSSEPSYLAAATTAVYEAMTAVDTEAVWLLQGWLFQHQPQF
Sbjct: 301 KEFGTDHIYGADTFNEMQPPSSEPSYLAAATTAVYEAMTAVDTEAVWLLQGWLFQHQPQF 360

Query: 361 WGPAQIRAVLGAVPRGRLLVLDLFAESQPVYTRTASFQGQPFIWCMLHNFGGNHGLFGAL 420
           WGPAQIRAVLGAVPRGRLLVLDLFAESQPVYTRTASFQGQPFIWCMLHNFGGNHGLFGAL
Sbjct: 361 WGPAQIRAVLGAVPRGRLLVLDLFAESQPVYTRTASFQGQPFIWCMLHNFGGNHGLFGAL 420

Query: 421 EAVNGGPEAARLFPNSTMVGTGMAPEGISQNEVVYSLMAELGWRKDPVPDLAAWVTSFAA 480
           EAVNGGPEAARLFPNSTMVGTGMAPEGISQNEVVYSLMAELGWRKDPVPDLAAWVTSFAA
Sbjct: 421 EAVNGGPEAARLFPNSTMVGTGMAPEGISQNEVVYSLMAELGWRKDPVPDLAAWVTSFAA 480

Query: 481 RRYGVSHPDAGAAWRLLLRSVYNCSGEACRGHNRSPLVRRPSLQMNTSIWYNRSDVFEAW 540
           RRYGVSHPDAGAAWRLLLRSVYNCSGEACRGHNRSPLVRRPSLQMNTSIWYNRSDVFEAW
Sbjct: 481 RRYGVSHPDAGAAWRLLLRSVYNCSGEACRGHNRSPLVRRPSLQMNTSIWYNRSDVFEAW 540

Query: 541 RLLLTSAPSLATSPAFRYDLLDLTRQAVQELVSLYYEEARSAYLSKELASLLRAGGVLAY 600
           RLLLTSAPSLATSPAFRYDLLDLTRQAVQELVSLYYEEARSAYLSKELASLLRAGGVLAY
Sbjct: 541 RLLLTSAPSLATSPAFRYDLLDLTRQAVQELVSLYYEEARSAYLSKELASLLRAGGVLAY 600

Query: 601 ELLPALDEVLASDSRFLLGSWLEQARAAAVSEAEADFYEQNSRYQLTLWGPEGNILDYAN 660
           ELLPALDEVLASDSRFLLGSWLEQARAAAVSEAEADFYEQNSRYQLTLWGPEGNILDYAN
Sbjct: 601 ELLPALDEVLASDSRFLLGSWLEQARAAAVSEAEADFYEQNSRYQLTLWGPEGNILDYAN 660

Query: 661 KQLAGLVANYYTPRWRLFLEALVDSVAQGIPFQQHQFDKNVFQLEQAFVLSKQRYPSQPR 720
           KQLAGLVANYYTPRWRLFLEALVDSVAQGIPFQQHQFDKNVFQLEQAFVLSKQRYPSQPR
Sbjct: 661 KQLAGLVANYYTPRWRLFLEALVDSVAQGIPFQQHQFDKNVFQLEQAFVLSKQRYPSQPR 720

Query: 721 GDTVDLAKKIFLKYYPRWVAGSW 743
           GDTVDLAKKIFLKYYPRWVAGSW
Sbjct: 721 GDTVDLAKKIFLKYYPRWVAGSW 743


>gi|160948610 E3 ubiquitin-protein ligase UBR3 [Homo sapiens]
          Length = 1888

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 34/107 (31%), Positives = 48/107 (44%), Gaps = 10/107 (9%)

Query: 3   AVAVAAAVGVLLLAG----AGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVERALAA 58
           A A AAAVG    +     A G A D+A  AA ++A ++R      A +    +ER L+A
Sbjct: 2   AAAAAAAVGGQQPSQPELPAPGLALDKAATAAHLKAALSRPDNRAGAEELQALLERVLSA 61

Query: 59  KPGLDTYSLGGGGAARVRVRGSTGVAAAAGLHRYLRDFCGCHVAWSG 105
           +  L   + GG  AA     G  G A    L     ++C C +A  G
Sbjct: 62  ERPL-AAAAGGEDAAAAGGGGGPGAAEEEAL-----EWCKCLLAGGG 102


>gi|46049110 myosin binding protein C, slow type isoform 4 [Homo
           sapiens]
          Length = 1123

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 9/105 (8%)

Query: 487 HPDAGAAWRLLLRSVYNCSGEACRGHNR---SPLVRRPSLQMNTSIWYNRSDVFEAWRLL 543
           H   G    + +RS +  SGE          S L++R  ++             + W LL
Sbjct: 160 HESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQ-----EEEPQVDVWELL 214

Query: 544 LTSAPSLATSPAFRYDLLDLTRQAVQELVSLYYEEARSAYLSKEL 588
             + PS     AF+Y + DL R  ++ L  +  EE +SA  +K L
Sbjct: 215 KNAKPSEYEKIAFQYGITDL-RGMLKRLKRMRREEKKSAAFAKIL 258


>gi|46049119 myosin binding protein C, slow type isoform 3 [Homo
           sapiens]
          Length = 1141

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 9/105 (8%)

Query: 487 HPDAGAAWRLLLRSVYNCSGEACRGHNR---SPLVRRPSLQMNTSIWYNRSDVFEAWRLL 543
           H   G    + +RS +  SGE          S L++R  ++             + W LL
Sbjct: 160 HESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQ-----EEEPQVDVWELL 214

Query: 544 LTSAPSLATSPAFRYDLLDLTRQAVQELVSLYYEEARSAYLSKEL 588
             + PS     AF+Y + DL R  ++ L  +  EE +SA  +K L
Sbjct: 215 KNAKPSEYEKIAFQYGITDL-RGMLKRLKRMRREEKKSAAFAKIL 258


>gi|46049125 myosin binding protein C, slow type isoform 2 [Homo
           sapiens]
          Length = 1148

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 9/105 (8%)

Query: 487 HPDAGAAWRLLLRSVYNCSGEACRGHNR---SPLVRRPSLQMNTSIWYNRSDVFEAWRLL 543
           H   G    + +RS +  SGE          S L++R  ++             + W LL
Sbjct: 185 HESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQ-----EEEPQVDVWELL 239

Query: 544 LTSAPSLATSPAFRYDLLDLTRQAVQELVSLYYEEARSAYLSKEL 588
             + PS     AF+Y + DL R  ++ L  +  EE +SA  +K L
Sbjct: 240 KNAKPSEYEKIAFQYGITDL-RGMLKRLKRMRREEKKSAAFAKIL 283


>gi|45976288 myosin binding protein C, slow type isoform 1 [Homo
           sapiens]
          Length = 1171

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 9/105 (8%)

Query: 487 HPDAGAAWRLLLRSVYNCSGEACRGHNR---SPLVRRPSLQMNTSIWYNRSDVFEAWRLL 543
           H   G    + +RS +  SGE          S L++R  ++             + W LL
Sbjct: 185 HESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQ-----EEEPQVDVWELL 239

Query: 544 LTSAPSLATSPAFRYDLLDLTRQAVQELVSLYYEEARSAYLSKEL 588
             + PS     AF+Y + DL R  ++ L  +  EE +SA  +K L
Sbjct: 240 KNAKPSEYEKIAFQYGITDL-RGMLKRLKRMRREEKKSAAFAKIL 283


>gi|19923957 major facilitator superfamily domain containing 3 [Homo
           sapiens]
          Length = 412

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 18/37 (48%), Positives = 21/37 (56%)

Query: 7   AAAVGVLLLAGAGGAAGDEAREAAAVRALVARLLGPG 43
           AA  G+LLL   G A  D A +A AV+ L    LGPG
Sbjct: 99  AAVAGLLLLLNLGAAMQDVALDALAVQLLEPAELGPG 135


>gi|5902108 SRY-box 21 [Homo sapiens]
          Length = 276

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 41/151 (27%), Positives = 50/151 (33%), Gaps = 39/151 (25%)

Query: 7   AAAVGVLLLAGAGGAAGDEA------REAAAVRALVARLLGPGPAADFSVSVERALAAKP 60
           A   G  L AGAGG    E+      + AAA  A  AR+  P  AA  + +   A A  P
Sbjct: 110 ALKAGAGLHAGAGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSP 169

Query: 61  ------------------GLDT-----YSLGGGGAARVRVRGSTGVAAAAGLHRYLRDF- 96
                             GL       Y   G GA       +   AAAAG H +     
Sbjct: 170 YSLLDLGSKMAEISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSP 229

Query: 97  --------CGCHVAWSGSQLRLPRPLPAVPG 119
                   C C  AW    L+ P     +PG
Sbjct: 230 GNPGYMIPCNCS-AWPSPGLQPPLAYILLPG 259


>gi|31543093 galactosidase, beta 1-like 2 [Homo sapiens]
          Length = 636

 Score = 30.4 bits (67), Expect = 6.2
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 4/48 (8%)

Query: 202 GRMGNLHTWDGPLPP----SWHIKQLYLQHRVLDQMRSFGMTPVLPAF 245
           G +GNL+  D PL      S  +K+ + Q   LD+  S   TP LPAF
Sbjct: 503 GLIGNLYLNDSPLKNFRIYSLDMKKSFFQRFGLDKWSSLPETPTLPAF 550


>gi|20162554 Kruppel-like factor 14 [Homo sapiens]
          Length = 323

 Score = 30.4 bits (67), Expect = 6.2
 Identities = 24/57 (42%), Positives = 26/57 (45%), Gaps = 10/57 (17%)

Query: 17 GAGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVERALAAKPGLDTYSLGGGGAA 73
          GAGGAAG E   A    AL     GPGP+   SV         P +   S G GGAA
Sbjct: 34 GAGGAAGSEVGAAHPESALP----GPGPSGPASV------PQLPQVPAPSPGAGGAA 80


>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 1 [Homo sapiens]
          Length = 501

 Score = 30.4 bits (67), Expect = 6.2
 Identities = 39/150 (26%), Positives = 60/150 (40%), Gaps = 12/150 (8%)

Query: 261 NVTKMGSWGHFNCSYSCSFLLAPEDPIFPI---IGSLFLRELIKEFGTDHIYGADTFNEM 317
           N T  G  G F   +  + L +    +FP    IGSL +  L+ +FG     GA  FN +
Sbjct: 51  NETYYGRTGEFMEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRK---GALLFNNI 107

Query: 318 QPPSSEPSYLAAAT-TAVYEAMTAVDTEAVWLLQGWLFQHQPQFWG---PAQIRAVLGAV 373
              S  P+ L   +  A    +  +    V +  G      P + G   P  +R  LG V
Sbjct: 108 F--SIVPAILMGCSRVATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVV 165

Query: 374 PRGRLLVLDLFAESQPVYTRTASFQGQPFI 403
           P+  + V  L A+   +    A+  G P +
Sbjct: 166 PQLFITVGILVAQIFGLRNLLANVDGWPIL 195


>gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens]
          Length = 1047

 Score = 30.4 bits (67), Expect = 6.2
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 8/73 (10%)

Query: 16 AGAGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVERALAAKPGLDTYSLGGGGAARV 75
          AG GGAA   +   A  R  +   L P  AA +   VE  +A        +LGGG A   
Sbjct: 18 AGGGGAAAGSSAYPAVCRVKIPAAL-PVAAAPYPGLVETGVAG-------TLGGGAALGS 69

Query: 76 RVRGSTGVAAAAG 88
             G+  VA A G
Sbjct: 70 EFLGAGSVAGALG 82


>gi|206725452 leukocyte receptor cluster (LRC) member 9 [Homo
           sapiens]
          Length = 501

 Score = 30.4 bits (67), Expect = 6.2
 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 18/110 (16%)

Query: 10  VGVLLLAGAGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVER-------ALAAKPGL 62
           + +L LAGAG        EAAA+ AL   LL PG  A   +S  +        L A P  
Sbjct: 365 LALLRLAGAG-------EEAAAIGALRRALLAPGLNAPPRLSFRKLVLLGPHVLCAPPSP 417

Query: 63  DTYSLGGGGAARVRVRGSTGVAAAAGLHRYLRDFCGCHVAWSGSQLRLPR 112
              S+    + R+   G + + +   LH +L      H    GSQ+ LP+
Sbjct: 418 TLESMAQVLSQRLEAEGLSTLQSPGQLHPHLTVAKVPH----GSQVHLPK 463


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 30.0 bits (66), Expect = 8.1
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 8/82 (9%)

Query: 17  GAGGAAGDEAREAAAVRAL----VARLLGPGPAADFSVSVERALAAKPGLDTYSLGGGGA 72
           G+GGA     ++AAA ++       R  G G     S S E+A+ A  G    + GG   
Sbjct: 741 GSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAK---SRSGEKAVTAG-GQKAAAAGGKKP 796

Query: 73  ARVRVRGSTGVAAAAGLHRYLR 94
            RV+ RG  G  AAAG  + LR
Sbjct: 797 PRVKSRGGRGQKAAAGGKKPLR 818


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,538,269
Number of Sequences: 37866
Number of extensions: 1366694
Number of successful extensions: 3359
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3355
Number of HSP's gapped (non-prelim): 18
length of query: 743
length of database: 18,247,518
effective HSP length: 110
effective length of query: 633
effective length of database: 14,082,258
effective search space: 8914069314
effective search space used: 8914069314
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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