Guide to the Human Genome
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Search of human proteins with 63003930

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|63003930 transmembrane protein 30B [Homo sapiens]
         (351 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|63003930 transmembrane protein 30B [Homo sapiens]                  744   0.0  
gi|8922720 transmembrane protein 30A isoform 1 [Homo sapiens]         364   e-101
gi|221139888 transmembrane protein 30A isoform 2 [Homo sapiens]       325   3e-89
gi|239753641 PREDICTED: transmembrane protein 30C [Homo sapiens]       39   0.007
gi|239748184 PREDICTED: transmembrane protein 30C [Homo sapiens]       39   0.007
gi|239742078 PREDICTED: transmembrane protein 30C [Homo sapiens]       39   0.007
gi|4503143 cathepsin D preproprotein [Homo sapiens]                    32   0.85 
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo...    32   1.1  
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo...    32   1.1  

>gi|63003930 transmembrane protein 30B [Homo sapiens]
          Length = 351

 Score =  744 bits (1920), Expect = 0.0
 Identities = 351/351 (100%), Positives = 351/351 (100%)

Query: 1   MTWSATARGAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGI 60
           MTWSATARGAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGI
Sbjct: 1   MTWSATARGAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGI 60

Query: 61  KELEYDYTGDPGTGNCSVCAAAGQGRALPPPCSCAWYFSLPELFQGPVYLYYELTNFYQN 120
           KELEYDYTGDPGTGNCSVCAAAGQGRALPPPCSCAWYFSLPELFQGPVYLYYELTNFYQN
Sbjct: 61  KELEYDYTGDPGTGNCSVCAAAGQGRALPPPCSCAWYFSLPELFQGPVYLYYELTNFYQN 120

Query: 121 NRRYGVSRDDAQLSGLPSALRHPVNECAPYQRSAAGLPIAPCGAIANSLFNDSFSLWHQR 180
           NRRYGVSRDDAQLSGLPSALRHPVNECAPYQRSAAGLPIAPCGAIANSLFNDSFSLWHQR
Sbjct: 121 NRRYGVSRDDAQLSGLPSALRHPVNECAPYQRSAAGLPIAPCGAIANSLFNDSFSLWHQR 180

Query: 181 QPGGPYVEVPLDRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTAPPPNWRRPVYELSPDP 240
           QPGGPYVEVPLDRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTAPPPNWRRPVYELSPDP
Sbjct: 181 QPGGPYVEVPLDRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTAPPPNWRRPVYELSPDP 240

Query: 241 NNTGFINQDFVVWMRTAALPTFRKLYARIRQGNYSAGLPRGAYRVNITYNYPVRAFGGHK 300
           NNTGFINQDFVVWMRTAALPTFRKLYARIRQGNYSAGLPRGAYRVNITYNYPVRAFGGHK
Sbjct: 241 NNTGFINQDFVVWMRTAALPTFRKLYARIRQGNYSAGLPRGAYRVNITYNYPVRAFGGHK 300

Query: 301 LLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQDQDDDDEE 351
           LLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQDQDDDDEE
Sbjct: 301 LLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQDQDDDDEE 351


>gi|8922720 transmembrane protein 30A isoform 1 [Homo sapiens]
          Length = 361

 Score =  364 bits (935), Expect = e-101
 Identities = 181/337 (53%), Positives = 234/337 (69%), Gaps = 9/337 (2%)

Query: 12  QPDNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGIKELEYDYTGDP 71
           +PDNTAF QQRLPAWQP+L+A   LP+FF  GL FI +G+G++ +SN I+E+E DYTG  
Sbjct: 27  RPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGLIFIPIGIGIFVTSNNIREIEIDYTGTE 86

Query: 72  GTGNCSVCAAAGQGRALPPPCSCAWYFSLPELFQGPVYLYYELTNFYQNNRRYGVSRDDA 131
            +  C+ C +         PC C   F+L + F+G V++YY L+NFYQN+RRY  SRDD+
Sbjct: 87  PSSPCNKCLSPDV-----TPCFCTINFTLEKSFEGNVFMYYGLSNFYQNHRRYVKSRDDS 141

Query: 132 QLSGLPSALRHPVNECAPYQRSAAGLPIAPCGAIANSLFNDSFSLWHQRQPGGPYVEVPL 191
           QL+G  SAL +P  EC PY+R+    PIAPCGAIANS+FND+  L+       P + + L
Sbjct: 142 QLNGDSSALLNPSKECEPYRRNE-DKPIAPCGAIANSMFNDTLELFLIGNDSYP-IPIAL 199

Query: 192 DRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTAPPPNWRRPVYELSPDPNNTGFINQDFV 251
            + GIAWWTD +VKFRNPP    +L   F+GT  P NW +PVY L  DP+N GFIN+DF+
Sbjct: 200 KKKGIAWWTDKNVKFRNPP-GGDNLEERFKGTTKPVNWLKPVYMLDSDPDNNGFINEDFI 258

Query: 252 VWMRTAALPTFRKLYARI-RQGNYSAGLPRGAYRVNITYNYPVRAFGGHKLLIFSSISWM 310
           VWMRTAALPTFRKLY  I R+ +    LP G Y +N+TYNYPV  F G K +I S+ISWM
Sbjct: 259 VWMRTAALPTFRKLYRLIERKSDLHPTLPAGRYSLNVTYNYPVHYFDGRKRMILSTISWM 318

Query: 311 GGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQDQDD 347
           GGKNPFLGIAY+ VGS+  L G V+LV+  +Y++  +
Sbjct: 319 GGKNPFLGIAYIAVGSISFLLGVVLLVINHKYRNSSN 355


>gi|221139888 transmembrane protein 30A isoform 2 [Homo sapiens]
          Length = 325

 Score =  325 bits (834), Expect = 3e-89
 Identities = 169/337 (50%), Positives = 216/337 (64%), Gaps = 45/337 (13%)

Query: 12  QPDNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGIKELEYDYTGDP 71
           +PDNTAF QQRLPAWQP+L+A   LP+FF  GL FI +G+G++ +SN I+E+E       
Sbjct: 27  RPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGLIFIPIGIGIFVTSNNIREIE------- 79

Query: 72  GTGNCSVCAAAGQGRALPPPCSCAWYFSLPELFQGPVYLYYELTNFYQNNRRYGVSRDDA 131
                                             G V++YY L+NFYQN+RRY  SRDD+
Sbjct: 80  ----------------------------------GNVFMYYGLSNFYQNHRRYVKSRDDS 105

Query: 132 QLSGLPSALRHPVNECAPYQRSAAGLPIAPCGAIANSLFNDSFSLWHQRQPGGPYVEVPL 191
           QL+G  SAL +P  EC PY+R+    PIAPCGAIANS+FND+  L+       P + + L
Sbjct: 106 QLNGDSSALLNPSKECEPYRRNE-DKPIAPCGAIANSMFNDTLELFLIGNDSYP-IPIAL 163

Query: 192 DRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTAPPPNWRRPVYELSPDPNNTGFINQDFV 251
            + GIAWWTD +VKFRNPP    +L   F+GT  P NW +PVY L  DP+N GFIN+DF+
Sbjct: 164 KKKGIAWWTDKNVKFRNPP-GGDNLEERFKGTTKPVNWLKPVYMLDSDPDNNGFINEDFI 222

Query: 252 VWMRTAALPTFRKLYARI-RQGNYSAGLPRGAYRVNITYNYPVRAFGGHKLLIFSSISWM 310
           VWMRTAALPTFRKLY  I R+ +    LP G Y +N+TYNYPV  F G K +I S+ISWM
Sbjct: 223 VWMRTAALPTFRKLYRLIERKSDLHPTLPAGRYSLNVTYNYPVHYFDGRKRMILSTISWM 282

Query: 311 GGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQDQDD 347
           GGKNPFLGIAY+ VGS+  L G V+LV+  +Y++  +
Sbjct: 283 GGKNPFLGIAYIAVGSISFLLGVVLLVINHKYRNSSN 319


>gi|239753641 PREDICTED: transmembrane protein 30C [Homo sapiens]
          Length = 113

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 6/88 (6%)

Query: 14  DNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGIKELEYDYTGDPGT 73
           DN+A  QQ LP  +   +A   L +FF  G+  + +G+ L  S+   +E+E +Y     T
Sbjct: 14  DNSALKQQELPIHRLYFTARRVLFVFFATGIFCLCMGIILILSARSTQEIEINY-----T 68

Query: 74  GNCSVCAAAGQGRA-LPPPCSCAWYFSL 100
             C+ CA   +  +     C+C+  F L
Sbjct: 69  RICANCAKLRENASNFDKECTCSIPFYL 96


>gi|239748184 PREDICTED: transmembrane protein 30C [Homo sapiens]
          Length = 113

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 6/88 (6%)

Query: 14  DNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGIKELEYDYTGDPGT 73
           DN+A  QQ LP  +   +A   L +FF  G+  + +G+ L  S+   +E+E +Y     T
Sbjct: 14  DNSALKQQELPIHRLYFTARRVLFVFFATGIFCLCMGIILILSARSTQEIEINY-----T 68

Query: 74  GNCSVCAAAGQGRA-LPPPCSCAWYFSL 100
             C+ CA   +  +     C+C+  F L
Sbjct: 69  RICANCAKLRENASNFDKECTCSIPFYL 96


>gi|239742078 PREDICTED: transmembrane protein 30C [Homo sapiens]
          Length = 113

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 6/88 (6%)

Query: 14  DNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGIKELEYDYTGDPGT 73
           DN+A  QQ LP  +   +A   L +FF  G+  + +G+ L  S+   +E+E +Y     T
Sbjct: 14  DNSALKQQELPIHRLYFTARRVLFVFFATGIFCLCMGIILILSARSTQEIEINY-----T 68

Query: 74  GNCSVCAAAGQGRA-LPPPCSCAWYFSL 100
             C+ CA   +  +     C+C+  F L
Sbjct: 69  RICANCAKLRENASNFDKECTCSIPFYL 96


>gi|4503143 cathepsin D preproprotein [Homo sapiens]
          Length = 412

 Score = 32.0 bits (71), Expect = 0.85
 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 11/98 (11%)

Query: 28  PLLSASIALPLFFCAGLAFIGLGLGLYYSSNGIKELEYDYTGDPGTGNCSVCAAAGQGRA 87
           PL+     +P    + L  I L LG      G K    DYT        ++C +   G  
Sbjct: 319 PLIQGEYMIPCEKVSTLPAITLKLG----GKGYKLSPEDYTLKVSQAGKTLCLSGFMGMD 374

Query: 88  LPPPCSCAWYFSLPELFQGPVYLYYELTNFYQNNRRYG 125
           +PPP    W   L ++F G  Y     T F ++N R G
Sbjct: 375 IPPPSGPLWI--LGDVFIGRYY-----TVFDRDNNRVG 405


>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 43/185 (23%), Positives = 60/185 (32%), Gaps = 34/185 (18%)

Query: 80  AAAGQGRALPPP----------CSCAWYFSLPELFQGPVYLYYELTNFYQNNRRYGVSRD 129
           +AA  G  +PPP          C   W     ++F+ P +L+      +   + +  S  
Sbjct: 330 SAAPAGVGVPPPATGGGDGPFACPLCW-----KVFKKPSHLHQHQI-IHTGEKPFSCSVC 383

Query: 130 DAQLSGLPSALRHPVNECAPYQRSAAGLPIAPCGAIANSLFNDSFSLWHQRQ-----PGG 184
               +   S  RH     A   R        PCG    +  + S+ L HQ        GG
Sbjct: 384 SKSFNRRESLKRHVKTHSADLLR-------LPCGICGKAFRDASYLLKHQAAHAGAGAGG 436

Query: 185 PYVEVPLDRSGIAWWTDY----HVKFRNPPLVNGSLAL--AFQGTAPPPNWRRPVYELSP 238
           P    P D  G ++        H     PP          A     PPP +    Y L P
Sbjct: 437 PRPVYPCDLCGKSYSAPQSLLRHKAAHAPPAAAAEAPKDGAASAPQPPPTFPPGPYLLPP 496

Query: 239 DPNNT 243
           DP  T
Sbjct: 497 DPPTT 501


>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 43/185 (23%), Positives = 60/185 (32%), Gaps = 34/185 (18%)

Query: 80  AAAGQGRALPPP----------CSCAWYFSLPELFQGPVYLYYELTNFYQNNRRYGVSRD 129
           +AA  G  +PPP          C   W     ++F+ P +L+      +   + +  S  
Sbjct: 330 SAAPAGVGVPPPATGGGDGPFACPLCW-----KVFKKPSHLHQHQI-IHTGEKPFSCSVC 383

Query: 130 DAQLSGLPSALRHPVNECAPYQRSAAGLPIAPCGAIANSLFNDSFSLWHQRQ-----PGG 184
               +   S  RH     A   R        PCG    +  + S+ L HQ        GG
Sbjct: 384 SKSFNRRESLKRHVKTHSADLLR-------LPCGICGKAFRDASYLLKHQAAHAGAGAGG 436

Query: 185 PYVEVPLDRSGIAWWTDY----HVKFRNPPLVNGSLAL--AFQGTAPPPNWRRPVYELSP 238
           P    P D  G ++        H     PP          A     PPP +    Y L P
Sbjct: 437 PRPVYPCDLCGKSYSAPQSLLRHKAAHAPPAAAAEAPKDGAASAPQPPPTFPPGPYLLPP 496

Query: 239 DPNNT 243
           DP  T
Sbjct: 497 DPPTT 501


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.140    0.461 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,308,665
Number of Sequences: 37866
Number of extensions: 834320
Number of successful extensions: 1637
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1621
Number of HSP's gapped (non-prelim): 10
length of query: 351
length of database: 18,247,518
effective HSP length: 103
effective length of query: 248
effective length of database: 14,347,320
effective search space: 3558135360
effective search space used: 3558135360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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