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Search of human proteins with 6031192
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6031192 solute carrier family 25 member 3 isoform a
precursor [Homo sapiens]
(362 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6031192 solute carrier family 25 member 3 isoform a precursor... 737 0.0
gi|4505775 solute carrier family 25 member 3 isoform b precursor... 714 0.0
gi|47132595 solute carrier family 25 member 3 isoform b precurso... 714 0.0
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 89 6e-18
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 89 6e-18
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 89 6e-18
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 80 3e-15
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 80 4e-15
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 79 5e-15
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 79 5e-15
gi|21389315 solute carrier family 25 (mitochondrial carrier; cit... 78 1e-14
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 75 7e-14
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 75 7e-14
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 75 7e-14
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 75 7e-14
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 75 7e-14
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 75 7e-14
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 75 7e-14
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 75 7e-14
gi|13994341 solute carrier family 25 member 2 [Homo sapiens] 75 1e-13
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 73 3e-13
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 72 8e-13
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 71 1e-12
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 71 1e-12
gi|11225256 uncoupling protein 1 [Homo sapiens] 70 3e-12
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 70 4e-12
gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens] 69 7e-12
gi|21361114 solute carrier family 25 (mitochondrial carrier; oxo... 69 9e-12
gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 67 2e-11
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 67 3e-11
>gi|6031192 solute carrier family 25 member 3 isoform a precursor
[Homo sapiens]
Length = 362
Score = 737 bits (1903), Expect = 0.0
Identities = 362/362 (100%), Positives = 362/362 (100%)
Query: 1 MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEQYSCDYG 60
MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEQYSCDYG
Sbjct: 1 MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEQYSCDYG 60
Query: 61 SGRFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA 120
SGRFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA
Sbjct: 61 SGRFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA 120
Query: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 180
KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL
Sbjct: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 180
Query: 181 APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER 240
APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER
Sbjct: 181 APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER 240
Query: 241 TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS 300
TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS
Sbjct: 241 TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS 300
Query: 301 LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL 360
LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL
Sbjct: 301 LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL 360
Query: 361 TQ 362
TQ
Sbjct: 361 TQ 362
>gi|4505775 solute carrier family 25 member 3 isoform b precursor
[Homo sapiens]
Length = 361
Score = 714 bits (1842), Expect = 0.0
Identities = 349/362 (96%), Positives = 357/362 (98%), Gaps = 1/362 (0%)
Query: 1 MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEQYSCDYG 60
MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEE YSC++G
Sbjct: 1 MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEE-YSCEFG 59
Query: 61 SGRFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA 120
S +++ LCG GG++SCG THTA+VPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA
Sbjct: 60 SAKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA 119
Query: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 180
KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL
Sbjct: 120 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 179
Query: 181 APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER 240
APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER
Sbjct: 180 APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER 239
Query: 241 TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS 300
TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS
Sbjct: 240 TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS 299
Query: 301 LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL 360
LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL
Sbjct: 300 LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL 359
Query: 361 TQ 362
TQ
Sbjct: 360 TQ 361
>gi|47132595 solute carrier family 25 member 3 isoform b precursor
[Homo sapiens]
Length = 361
Score = 714 bits (1842), Expect = 0.0
Identities = 349/362 (96%), Positives = 357/362 (98%), Gaps = 1/362 (0%)
Query: 1 MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEQYSCDYG 60
MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEE YSC++G
Sbjct: 1 MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEE-YSCEFG 59
Query: 61 SGRFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA 120
S +++ LCG GG++SCG THTA+VPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA
Sbjct: 60 SAKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA 119
Query: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 180
KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL
Sbjct: 120 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 179
Query: 181 APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER 240
APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER
Sbjct: 180 APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER 239
Query: 241 TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS 300
TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS
Sbjct: 240 TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS 299
Query: 301 LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL 360
LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL
Sbjct: 300 LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL 359
Query: 361 TQ 362
TQ
Sbjct: 360 TQ 361
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 89.0 bits (219), Expect = 6e-18
Identities = 78/294 (26%), Positives = 130/294 (44%), Gaps = 38/294 (12%)
Query: 70 LGGIISCGTTHTALVPLDLVKCRMQV--------DPQ-KYKGIFNGFSVTLKEDGVRGLA 120
+ G +S T + P D++K R Q+ DP KY GI L+E+G
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRT-SLYLAASASAEFFADIA 179
KG P + G +F +E+ + ++ + Y R S++ A A +
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEML----TELVHRGSVYDAREFSVHFVCGGLAACMATLT 135
Query: 180 LAPMEAAKVRI--QTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFAC 237
+ P++ + R Q +P NTLR A MY+ EG + FYKG+AP + PY ++F+C
Sbjct: 136 VHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSC 195
Query: 238 FERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD------------ 285
+ +++ LYK+ +P +E K E L + G AGV +++P D
Sbjct: 196 YS-SLKHLYKWAIP---AEGKKNENL-QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFE 250
Query: 286 ---SVVSVLNKEKG--SSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYD 334
+ + + KG A VL++ G G +KGL ++ T +F Y+
Sbjct: 251 HARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 50.8 bits (120), Expect = 2e-06
Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 33/219 (15%)
Query: 162 TSLYLAASASAEFFADIAL-APMEAAKVRIQTQ---------PGYANTLRDAAPKMYKEE 211
T +A + S AL +P + K+R Q Q + + A+ ++ +EE
Sbjct: 14 TKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEE 73
Query: 212 GLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGY 271
G AF+KG P + I Y ++F FE E +++ V R + V FV G
Sbjct: 74 GPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAR-------EFSVHFVCGG 126
Query: 272 IAGVFCAIVSHPAD------------SVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARI 319
+A + HP D V + L G+ + + G + +KGL +
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGT----MYRSEGPQVFYKGLAPTL 182
Query: 320 IMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKL 358
I I LQ+ Y S+K ++ P + E+L+ L
Sbjct: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLL 221
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 89.0 bits (219), Expect = 6e-18
Identities = 78/294 (26%), Positives = 130/294 (44%), Gaps = 38/294 (12%)
Query: 70 LGGIISCGTTHTALVPLDLVKCRMQV--------DPQ-KYKGIFNGFSVTLKEDGVRGLA 120
+ G +S T + P D++K R Q+ DP KY GI L+E+G
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRT-SLYLAASASAEFFADIA 179
KG P + G +F +E+ + ++ + Y R S++ A A +
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEML----TELVHRGSVYDAREFSVHFVCGGLAACMATLT 135
Query: 180 LAPMEAAKVRI--QTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFAC 237
+ P++ + R Q +P NTLR A MY+ EG + FYKG+AP + PY ++F+C
Sbjct: 136 VHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSC 195
Query: 238 FERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD------------ 285
+ +++ LYK+ +P +E K E L + G AGV +++P D
Sbjct: 196 YS-SLKHLYKWAIP---AEGKKNENL-QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFE 250
Query: 286 ---SVVSVLNKEKG--SSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYD 334
+ + + KG A VL++ G G +KGL ++ T +F Y+
Sbjct: 251 HARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 50.8 bits (120), Expect = 2e-06
Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 33/219 (15%)
Query: 162 TSLYLAASASAEFFADIAL-APMEAAKVRIQTQ---------PGYANTLRDAAPKMYKEE 211
T +A + S AL +P + K+R Q Q + + A+ ++ +EE
Sbjct: 14 TKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEE 73
Query: 212 GLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGY 271
G AF+KG P + I Y ++F FE E +++ V R + V FV G
Sbjct: 74 GPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAR-------EFSVHFVCGG 126
Query: 272 IAGVFCAIVSHPAD------------SVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARI 319
+A + HP D V + L G+ + + G + +KGL +
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGT----MYRSEGPQVFYKGLAPTL 182
Query: 320 IMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKL 358
I I LQ+ Y S+K ++ P + E+L+ L
Sbjct: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLL 221
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 89.0 bits (219), Expect = 6e-18
Identities = 78/294 (26%), Positives = 130/294 (44%), Gaps = 38/294 (12%)
Query: 70 LGGIISCGTTHTALVPLDLVKCRMQV--------DPQ-KYKGIFNGFSVTLKEDGVRGLA 120
+ G +S T + P D++K R Q+ DP KY GI L+E+G
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRT-SLYLAASASAEFFADIA 179
KG P + G +F +E+ + ++ + Y R S++ A A +
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEML----TELVHRGSVYDAREFSVHFVCGGLAACMATLT 135
Query: 180 LAPMEAAKVRI--QTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFAC 237
+ P++ + R Q +P NTLR A MY+ EG + FYKG+AP + PY ++F+C
Sbjct: 136 VHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSC 195
Query: 238 FERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD------------ 285
+ +++ LYK+ +P +E K E L + G AGV +++P D
Sbjct: 196 YS-SLKHLYKWAIP---AEGKKNENL-QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFE 250
Query: 286 ---SVVSVLNKEKG--SSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYD 334
+ + + KG A VL++ G G +KGL ++ T +F Y+
Sbjct: 251 HARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 50.8 bits (120), Expect = 2e-06
Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 33/219 (15%)
Query: 162 TSLYLAASASAEFFADIAL-APMEAAKVRIQTQ---------PGYANTLRDAAPKMYKEE 211
T +A + S AL +P + K+R Q Q + + A+ ++ +EE
Sbjct: 14 TKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEE 73
Query: 212 GLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGY 271
G AF+KG P + I Y ++F FE E +++ V R + V FV G
Sbjct: 74 GPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAR-------EFSVHFVCGG 126
Query: 272 IAGVFCAIVSHPAD------------SVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARI 319
+A + HP D V + L G+ + + G + +KGL +
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGT----MYRSEGPQVFYKGLAPTL 182
Query: 320 IMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKL 358
I I LQ+ Y S+K ++ P + E+L+ L
Sbjct: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLL 221
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 80.1 bits (196), Expect = 3e-15
Identities = 79/236 (33%), Positives = 105/236 (44%), Gaps = 33/236 (13%)
Query: 69 GLGGIISCGTTHTALVPLDLVKCRMQVDPQK-------YKGIFNGFSVTLKEDGVRGLAK 121
G GG+ H PLD VK R+Q P Y G F+ F TL +G+ GL +
Sbjct: 18 GFGGVCLVFVGH----PLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYR 73
Query: 122 GWAPTFLGYS-MQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 180
G A +G + M +C FGF + K L + +Y L+ A S F I +
Sbjct: 74 GMAAPIIGVTPMFAVCFFGF-GLGKKLQQKHPEDVLSY---PQLFAAGMLSGVFTTGI-M 128
Query: 181 APMEAAKVRIQTQPG-----YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKF 235
P E K +Q Q Y TL D A K+Y+E G++ YKG MR +P + M F
Sbjct: 129 TPGERIKCLLQIQASSGESKYTGTL-DCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYF 187
Query: 236 ACFERTVEALYKFVVPKPR--SECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVS 289
T E L P+ + SE S P L VAG IAG+F V+ P D + S
Sbjct: 188 ----MTYEWLKNIFTPEGKRVSELSAPRIL----VAGGIAGIFNWAVAIPPDVLKS 235
Score = 55.5 bits (132), Expect = 7e-08
Identities = 47/180 (26%), Positives = 80/180 (44%), Gaps = 8/180 (4%)
Query: 72 GIISCGTTHTALVPLDLVKCRMQVDPQ----KYKGIFNGFSVTLKEDGVRGLAKGWAPTF 127
G++S T + P + +KC +Q+ KY G + +E G+RG+ KG T
Sbjct: 117 GMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTL 176
Query: 128 LGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAK 187
+ F YE K +++ G+ + L + +A + F +A+ P + K
Sbjct: 177 MRDVPASGMYFMTYEWLKNIFTPE-GKRVSELSAPRILVAGGIAGIFNWAVAIPP-DVLK 234
Query: 188 VRIQTQPG--YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEAL 245
R QT P Y N RD ++ ++EG+ + YKG + +R P F FE ++ L
Sbjct: 235 SRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFL 294
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 79.7 bits (195), Expect = 4e-15
Identities = 45/142 (31%), Positives = 75/142 (52%), Gaps = 1/142 (0%)
Query: 98 QKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENT 157
++YKG+F+ K +GVRGL KG+ P G S G +F YE+ K+ Y+ +
Sbjct: 161 RQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGTS-HGALQFMAYELLKLKYNQHINRLPE 219
Query: 158 YLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFY 217
T Y++ +A ++ FA A P + + R+Q Q + + + D K +++EG+ FY
Sbjct: 220 AQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGGFY 279
Query: 218 KGVAPLWMRQIPYTMMKFACFE 239
KG+AP +R P + F +E
Sbjct: 280 KGIAPNLIRVTPACCITFVVYE 301
Score = 66.6 bits (161), Expect = 3e-11
Identities = 67/285 (23%), Positives = 117/285 (41%), Gaps = 32/285 (11%)
Query: 71 GGIISCGTTHTALVPLDLVKCRMQVDP-----QKYKGIFNGFSVTLKEDGVRGLAKGWAP 125
GG++S + AL PLDLVK R V KY GI + + K DG+RGL +G P
Sbjct: 32 GGVLS----NLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQGVTP 87
Query: 126 TFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEA 185
G + F FY K + E + YL ++A A P+
Sbjct: 88 NIWGAGLSWGLYFFFYNAIKSYKTEGRAER----LEATEYLVSAAEAGAMTLCITNPLWV 143
Query: 186 AKVRIQTQ-PGYANT-------LRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFAC 237
K R+ Q N+ + D K+YK EG++ YKG P + + ++F
Sbjct: 144 TKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVP-GLFGTSHGALQFMA 202
Query: 238 FERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGS 297
+E + + P ++ S E + V ++ +F ++P V + L +
Sbjct: 203 YELLKLKYNQHINRLPEAQLSTVEYISV----AALSKIFAVAATYPYQVVRARLQDQHMF 258
Query: 298 SASLV------LKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSV 336
+ ++ ++ G G +KG+ +I + + + +Y++V
Sbjct: 259 YSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENV 303
Score = 37.0 bits (84), Expect = 0.028
Identities = 47/196 (23%), Positives = 91/196 (46%), Gaps = 32/196 (16%)
Query: 166 LAASASAEFFADIALAPMEAAKVR------IQTQPGYANTLRDAAPKMYKEEGLKAFYKG 219
L A S +++AL P++ K+R ++ +P Y N + ++K +GL+ Y+G
Sbjct: 26 LIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKY-NGILHCLTTIWKLDGLRGLYQG 84
Query: 220 VAP-LWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCA 278
V P +W + + + F F +++ YK R E ++ V+ AG
Sbjct: 85 VTPNIWGAGLSWGLYFF--FYNAIKS-YKTEGRAERLEATE------YLVSAAEAGAMTL 135
Query: 279 IVSHPA-----------DSVVSVLNKE-KGSSASLV--LKRLGFKGVWKGLFARIIMIGT 324
+++P D+VV+ +++ KG +LV K G +G++KG F + +
Sbjct: 136 CITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKG-FVPGLFGTS 194
Query: 325 LTALQWFIYDSVKVYF 340
ALQ+ Y+ +K+ +
Sbjct: 195 HGALQFMAYELLKLKY 210
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 79.3 bits (194), Expect = 5e-15
Identities = 71/281 (25%), Positives = 122/281 (43%), Gaps = 23/281 (8%)
Query: 70 LGGIISCGTTHTALVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTF 127
L G I+ + T+ PLD +K MQV K IF GF +KE G+R L +G
Sbjct: 199 LAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNV 258
Query: 128 LGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAK 187
+ + + KF YE +K L L EE + +++ S + A + PME K
Sbjct: 259 IKIAPETAVKFWAYEQYKKL----LTEEGQKIGTFERFISGSMAGAT-AQTFIYPMEVMK 313
Query: 188 VRIQT-QPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALY 246
R+ + G + + D A K+ K EGL AFYKG P + IPY + A +E L
Sbjct: 314 TRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYE-----LL 368
Query: 247 KFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS------ 300
K ++ S ++V G ++ + S+P V + + + S
Sbjct: 369 KSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMV 428
Query: 301 ----LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 337
++ + G G+++G+ + + + + +Y+++K
Sbjct: 429 GLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMK 469
Score = 56.2 bits (134), Expect = 4e-08
Identities = 38/186 (20%), Positives = 81/186 (43%), Gaps = 16/186 (8%)
Query: 70 LGGIISCGTTHTALVPLDLVKCRMQVDPQ-KYKGIFNGFSVTLKEDGVRGLAKGWAPTFL 128
+ G ++ T T + P++++K R+ V +Y GI++ LK +G+ KG+ P L
Sbjct: 293 ISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLL 352
Query: 129 GYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKV 188
G YE+ K + + +++ + L A + +A P+ +
Sbjct: 353 GIIPYAGIDLAVYELLKSYWLDNFAKDSVNPG-VMVLLGCGALSSTCGQLASYPLALVRT 411
Query: 189 RIQTQPGYANTLRDAAPKM---------YKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 239
R+Q Q + + +P++ +EG+ Y+G+ P +M+ +P + + +E
Sbjct: 412 RMQAQ-----AMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 466
Query: 240 RTVEAL 245
+ L
Sbjct: 467 NMKQTL 472
Score = 38.1 bits (87), Expect = 0.012
Identities = 39/190 (20%), Positives = 80/190 (42%), Gaps = 21/190 (11%)
Query: 160 WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLR--DAAPKMYKEEGLKAFY 217
WR L A A + + AP++ K+ +Q ++ + +M KE G+++ +
Sbjct: 195 WRQ---LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLW 251
Query: 218 KGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFC 277
+G ++ P T +KF +E+ YK ++ + + E+ F++G +AG
Sbjct: 252 RGNGTNVIKIAPETAVKFWAYEQ-----YKKLLTEEGQKIGTFER----FISGSMAGATA 302
Query: 278 AIVSHPADSVVSVLNKEKGSS-------ASLVLKRLGFKGVWKGLFARIIMIGTLTALQW 330
+P + + + L K A +LK G +KG ++ I +
Sbjct: 303 QTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 362
Query: 331 FIYDSVKVYF 340
+Y+ +K Y+
Sbjct: 363 AVYELLKSYW 372
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 79.3 bits (194), Expect = 5e-15
Identities = 71/281 (25%), Positives = 122/281 (43%), Gaps = 23/281 (8%)
Query: 70 LGGIISCGTTHTALVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTF 127
L G I+ + T+ PLD +K MQV K IF GF +KE G+R L +G
Sbjct: 180 LAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNV 239
Query: 128 LGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAK 187
+ + + KF YE +K L L EE + +++ S + A + PME K
Sbjct: 240 IKIAPETAVKFWAYEQYKKL----LTEEGQKIGTFERFISGSMAGAT-AQTFIYPMEVMK 294
Query: 188 VRIQT-QPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALY 246
R+ + G + + D A K+ K EGL AFYKG P + IPY + A +E L
Sbjct: 295 TRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYE-----LL 349
Query: 247 KFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS------ 300
K ++ S ++V G ++ + S+P V + + + S
Sbjct: 350 KSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMV 409
Query: 301 ----LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 337
++ + G G+++G+ + + + + +Y+++K
Sbjct: 410 GLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMK 450
Score = 56.2 bits (134), Expect = 4e-08
Identities = 38/186 (20%), Positives = 81/186 (43%), Gaps = 16/186 (8%)
Query: 70 LGGIISCGTTHTALVPLDLVKCRMQVDPQ-KYKGIFNGFSVTLKEDGVRGLAKGWAPTFL 128
+ G ++ T T + P++++K R+ V +Y GI++ LK +G+ KG+ P L
Sbjct: 274 ISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLL 333
Query: 129 GYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKV 188
G YE+ K + + +++ + L A + +A P+ +
Sbjct: 334 GIIPYAGIDLAVYELLKSYWLDNFAKDSVNPG-VMVLLGCGALSSTCGQLASYPLALVRT 392
Query: 189 RIQTQPGYANTLRDAAPKM---------YKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 239
R+Q Q + + +P++ +EG+ Y+G+ P +M+ +P + + +E
Sbjct: 393 RMQAQ-----AMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 447
Query: 240 RTVEAL 245
+ L
Sbjct: 448 NMKQTL 453
Score = 38.1 bits (87), Expect = 0.012
Identities = 39/190 (20%), Positives = 80/190 (42%), Gaps = 21/190 (11%)
Query: 160 WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLR--DAAPKMYKEEGLKAFY 217
WR L A A + + AP++ K+ +Q ++ + +M KE G+++ +
Sbjct: 176 WRQ---LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLW 232
Query: 218 KGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFC 277
+G ++ P T +KF +E+ YK ++ + + E+ F++G +AG
Sbjct: 233 RGNGTNVIKIAPETAVKFWAYEQ-----YKKLLTEEGQKIGTFER----FISGSMAGATA 283
Query: 278 AIVSHPADSVVSVLNKEKGSS-------ASLVLKRLGFKGVWKGLFARIIMIGTLTALQW 330
+P + + + L K A +LK G +KG ++ I +
Sbjct: 284 QTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 343
Query: 331 FIYDSVKVYF 340
+Y+ +K Y+
Sbjct: 344 AVYELLKSYW 353
>gi|21389315 solute carrier family 25 (mitochondrial carrier;
citrate transporter), member 1 precursor [Homo sapiens]
Length = 311
Score = 78.2 bits (191), Expect = 1e-14
Identities = 84/317 (26%), Positives = 138/317 (43%), Gaps = 40/317 (12%)
Query: 40 PRRPRNLAAAAVEEQYSCDYGSGRFFILCGL-GGIISCGTTHTALVPLDLVKCRMQVD-- 96
PR PR LAAAA + G+ + GL GGI C T P + VK ++Q+D
Sbjct: 4 PRAPRALAAAAPASGKAKLTHPGKAILAGGLAGGIEICIT-----FPTEYVKTQLQLDER 58
Query: 97 --PQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGE 154
P +Y+GI + T++ GV GL +G + G + +FG +E SN + +
Sbjct: 59 SHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFE----FLSNHMRD 114
Query: 155 ENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRI---QTQP-----GYANTLRDAAPK 206
L T L + A + + PME KV+ QT P G+ + +R+
Sbjct: 115 AQGRLDSTRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVRE---- 170
Query: 207 MYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVT 266
+ +E+GLK Y+G+ ++Q ++F ++ Y+ P +KP ++T
Sbjct: 171 IVREQGLKGTYQGLTATVLKQGSNQAIRFFVM-TSLRNWYRGDNP------NKPMNPLIT 223
Query: 267 FVAGYIAGVFCAIVSHPADSVVSVLN-------KEKGSSASLVLKRLGFKGVWKGLFARI 319
V G IAG + P D + + + + +LK+ G K +KG R+
Sbjct: 224 GVFGAIAGAASVFGNTPLDVIKTRMQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRL 283
Query: 320 IMIGTLTALQWFIYDSV 336
+ A+ + IYD V
Sbjct: 284 GRVCLDVAIVFVIYDEV 300
Score = 60.1 bits (144), Expect = 3e-09
Identities = 50/188 (26%), Positives = 83/188 (44%), Gaps = 12/188 (6%)
Query: 66 ILCGLGGIISCGTTHTALVPLDLVKCRM---QVDPQ-KYKGIFNGFSVTLKEDGVRGLAK 121
+LCGLG ++ + P++ +K + Q P KY+G F+G ++E G++G +
Sbjct: 125 LLCGLGAGVAEAVV--VVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQ 182
Query: 122 GWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALA 181
G T L +F + Y + T ++ A + +A F +
Sbjct: 183 GLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGN---T 239
Query: 182 PMEAAKVRIQTQPG--YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 239
P++ K R+Q Y NT D ++ K+EGLKAFYKG P R + F ++
Sbjct: 240 PLDVIKTRMQGLEAHKYRNTW-DCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYD 298
Query: 240 RTVEALYK 247
V+ L K
Sbjct: 299 EVVKLLNK 306
Score = 39.3 bits (90), Expect = 0.006
Identities = 39/185 (21%), Positives = 79/185 (42%), Gaps = 24/185 (12%)
Query: 182 PMEAAKVRIQ----TQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFAC 237
P E K ++Q + P + D + + G+ Y+G++ L IP ++F
Sbjct: 45 PTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGM 104
Query: 238 FERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSH-PADSV-VSVLNKEK 295
FE F+ R + + + G AGV A+V P +++ V ++ +
Sbjct: 105 FE--------FLSNHMRDAQGRLDS-TRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQT 155
Query: 296 GSSASL---------VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPP 346
+ +++ G KG ++GL A ++ G+ A+++F+ S++ ++R P
Sbjct: 156 SPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPN 215
Query: 347 PPEMP 351
P P
Sbjct: 216 KPMNP 220
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 75.5 bits (184), Expect = 7e-14
Identities = 74/289 (25%), Positives = 126/289 (43%), Gaps = 27/289 (9%)
Query: 63 RFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLA 120
R + G G +S T PLD +K MQV + GI GF+ ++E G R L
Sbjct: 188 RHLVAGGGAGAVS----RTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLW 243
Query: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 180
+G L + + KF YE K ++G + L R L A + A A ++
Sbjct: 244 RGNGINVLKIAPESAIKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSI 298
Query: 181 APMEAAKVRIQTQP-GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 239
PME K R+ + G + + D A ++ EG+ AFYKG P + IPY + A +E
Sbjct: 299 YPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE 358
Query: 240 RTVEA-LYKFVVPKPRSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLN 292
A L + V + P V ++ G +A A+V + S+
Sbjct: 359 TLKNAWLQHYAV-----NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEG 413
Query: 293 KEKGSSASL---VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 338
+ + +SL +L+ G G+++GL + + ++ + +Y+++K+
Sbjct: 414 APEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 462
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 75.5 bits (184), Expect = 7e-14
Identities = 74/289 (25%), Positives = 126/289 (43%), Gaps = 27/289 (9%)
Query: 63 RFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLA 120
R + G G +S T PLD +K MQV + GI GF+ ++E G R L
Sbjct: 222 RHLVAGGGAGAVS----RTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLW 277
Query: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 180
+G L + + KF YE K ++G + L R L A + A A ++
Sbjct: 278 RGNGINVLKIAPESAIKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSI 332
Query: 181 APMEAAKVRIQTQP-GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 239
PME K R+ + G + + D A ++ EG+ AFYKG P + IPY + A +E
Sbjct: 333 YPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE 392
Query: 240 RTVEA-LYKFVVPKPRSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLN 292
A L + V + P V ++ G +A A+V + S+
Sbjct: 393 TLKNAWLQHYAV-----NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEG 447
Query: 293 KEKGSSASL---VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 338
+ + +SL +L+ G G+++GL + + ++ + +Y+++K+
Sbjct: 448 APEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 496
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 75.5 bits (184), Expect = 7e-14
Identities = 68/295 (23%), Positives = 127/295 (43%), Gaps = 39/295 (13%)
Query: 65 FILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQ---------KYKGIFNGFSVTLKEDG 115
F+ GL I++ P+DL K R+QV Q KY+G+F+ KE+G
Sbjct: 44 FVYGGLASIVA----EFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEG 99
Query: 116 VRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFF 175
V L G AP L + G K G Y+ K L+ L E+ T L + + +
Sbjct: 100 VLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERL-EDETLLINMICGVVSGVISSTI 158
Query: 176 ADIALAPMEAAKVRIQTQPG-YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMK 234
A+ P + K+R+Q Q + ++ + +Y++EG + ++GV P R ++
Sbjct: 159 AN----PTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVE 214
Query: 235 FACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD--------- 285
++ T + L + ++ FV+ + G+ A+ S+P D
Sbjct: 215 LPVYDITKKHLI--------LSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQ 266
Query: 286 -SVVSVLNKEKGSSASL--VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 337
++V ++ KG+ + + K GF ++KG + + +G + + Y+ +K
Sbjct: 267 RAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
Score = 55.8 bits (133), Expect = 6e-08
Identities = 45/200 (22%), Positives = 89/200 (44%), Gaps = 30/200 (15%)
Query: 160 WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANT---------LRDAAPKMYKE 210
W+ +Y A A+ P++ K R+Q Q + + A ++ KE
Sbjct: 41 WKPFVY---GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKE 97
Query: 211 EGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAG 270
EG+ A Y G+AP +RQ Y +K ++ +L + V E + E L++ + G
Sbjct: 98 EGVLALYSGIAPALLRQASYGTIKIGIYQ----SLKRLFV-----ERLEDETLLINMICG 148
Query: 271 YIAGVFCAIVSHPADSVVSVLNKEKGS--------SASLVLKRLGFKGVWKGLFARIIMI 322
++GV + +++P D V+ + + +GS S + ++ G +G+W+G+
Sbjct: 149 VVSGVISSTIANPTD-VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRA 207
Query: 323 GTLTALQWFIYDSVKVYFRL 342
+ ++ +YD K + L
Sbjct: 208 AIVVGVELPVYDITKKHLIL 227
Score = 31.2 bits (69), Expect = 1.5
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 13/86 (15%)
Query: 68 CGLGGIISCGTTHTALVPLDLVKCRMQVDP------QKYKGIFNGFSVTLKEDGVRGLAK 121
CGL G ++ P+D+V+ RM YKG +G K +G L K
Sbjct: 245 CGLAGALASN-------PVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 297
Query: 122 GWAPTFLGYSMQGLCKFGFYEVFKVL 147
G+ P +L + F YE K L
Sbjct: 298 GFWPNWLRLGPWNIIFFITYEQLKRL 323
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 75.5 bits (184), Expect = 7e-14
Identities = 68/295 (23%), Positives = 127/295 (43%), Gaps = 39/295 (13%)
Query: 65 FILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQ---------KYKGIFNGFSVTLKEDG 115
F+ GL I++ P+DL K R+QV Q KY+G+F+ KE+G
Sbjct: 41 FVYGGLASIVA----EFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEG 96
Query: 116 VRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFF 175
V L G AP L + G K G Y+ K L+ L E+ T L + + +
Sbjct: 97 VLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERL-EDETLLINMICGVVSGVISSTI 155
Query: 176 ADIALAPMEAAKVRIQTQPG-YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMK 234
A+ P + K+R+Q Q + ++ + +Y++EG + ++GV P R ++
Sbjct: 156 AN----PTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVE 211
Query: 235 FACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD--------- 285
++ T + L + ++ FV+ + G+ A+ S+P D
Sbjct: 212 LPVYDITKKHLI--------LSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQ 263
Query: 286 -SVVSVLNKEKGSSASL--VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 337
++V ++ KG+ + + K GF ++KG + + +G + + Y+ +K
Sbjct: 264 RAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 318
Score = 55.8 bits (133), Expect = 6e-08
Identities = 45/200 (22%), Positives = 89/200 (44%), Gaps = 30/200 (15%)
Query: 160 WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANT---------LRDAAPKMYKE 210
W+ +Y A A+ P++ K R+Q Q + + A ++ KE
Sbjct: 38 WKPFVY---GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKE 94
Query: 211 EGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAG 270
EG+ A Y G+AP +RQ Y +K ++ +L + V E + E L++ + G
Sbjct: 95 EGVLALYSGIAPALLRQASYGTIKIGIYQ----SLKRLFV-----ERLEDETLLINMICG 145
Query: 271 YIAGVFCAIVSHPADSVVSVLNKEKGS--------SASLVLKRLGFKGVWKGLFARIIMI 322
++GV + +++P D V+ + + +GS S + ++ G +G+W+G+
Sbjct: 146 VVSGVISSTIANPTD-VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRA 204
Query: 323 GTLTALQWFIYDSVKVYFRL 342
+ ++ +YD K + L
Sbjct: 205 AIVVGVELPVYDITKKHLIL 224
Score = 31.2 bits (69), Expect = 1.5
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 13/86 (15%)
Query: 68 CGLGGIISCGTTHTALVPLDLVKCRMQVDP------QKYKGIFNGFSVTLKEDGVRGLAK 121
CGL G ++ P+D+V+ RM YKG +G K +G L K
Sbjct: 242 CGLAGALASN-------PVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 294
Query: 122 GWAPTFLGYSMQGLCKFGFYEVFKVL 147
G+ P +L + F YE K L
Sbjct: 295 GFWPNWLRLGPWNIIFFITYEQLKRL 320
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 75.5 bits (184), Expect = 7e-14
Identities = 74/289 (25%), Positives = 126/289 (43%), Gaps = 27/289 (9%)
Query: 63 RFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLA 120
R + G G +S T PLD +K MQV + GI GF+ ++E G R L
Sbjct: 208 RHLVAGGGAGAVS----RTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLW 263
Query: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 180
+G L + + KF YE K ++G + L R L A + A A ++
Sbjct: 264 RGNGINVLKIAPESAIKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSI 318
Query: 181 APMEAAKVRIQTQP-GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 239
PME K R+ + G + + D A ++ EG+ AFYKG P + IPY + A +E
Sbjct: 319 YPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE 378
Query: 240 RTVEA-LYKFVVPKPRSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLN 292
A L + V + P V ++ G +A A+V + S+
Sbjct: 379 TLKNAWLQHYAV-----NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEG 433
Query: 293 KEKGSSASL---VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 338
+ + +SL +L+ G G+++GL + + ++ + +Y+++K+
Sbjct: 434 APEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 482
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 75.5 bits (184), Expect = 7e-14
Identities = 74/289 (25%), Positives = 126/289 (43%), Gaps = 27/289 (9%)
Query: 63 RFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLA 120
R + G G +S T PLD +K MQV + GI GF+ ++E G R L
Sbjct: 188 RHLVAGGGAGAVS----RTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLW 243
Query: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 180
+G L + + KF YE K ++G + L R L A + A A ++
Sbjct: 244 RGNGINVLKIAPESAIKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSI 298
Query: 181 APMEAAKVRIQTQP-GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 239
PME K R+ + G + + D A ++ EG+ AFYKG P + IPY + A +E
Sbjct: 299 YPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE 358
Query: 240 RTVEA-LYKFVVPKPRSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLN 292
A L + V + P V ++ G +A A+V + S+
Sbjct: 359 TLKNAWLQHYAV-----NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEG 413
Query: 293 KEKGSSASL---VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 338
+ + +SL +L+ G G+++GL + + ++ + +Y+++K+
Sbjct: 414 APEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 462
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 75.5 bits (184), Expect = 7e-14
Identities = 74/289 (25%), Positives = 126/289 (43%), Gaps = 27/289 (9%)
Query: 63 RFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLA 120
R + G G +S T PLD +K MQV + GI GF+ ++E G R L
Sbjct: 85 RHLVAGGGAGAVS----RTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLW 140
Query: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 180
+G L + + KF YE K ++G + L R L A + A A ++
Sbjct: 141 RGNGINVLKIAPESAIKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSI 195
Query: 181 APMEAAKVRIQTQP-GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 239
PME K R+ + G + + D A ++ EG+ AFYKG P + IPY + A +E
Sbjct: 196 YPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE 255
Query: 240 RTVEA-LYKFVVPKPRSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLN 292
A L + V + P V ++ G +A A+V + S+
Sbjct: 256 TLKNAWLQHYAV-----NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEG 310
Query: 293 KEKGSSASL---VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 338
+ + +SL +L+ G G+++GL + + ++ + +Y+++K+
Sbjct: 311 APEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 359
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 75.5 bits (184), Expect = 7e-14
Identities = 74/289 (25%), Positives = 126/289 (43%), Gaps = 27/289 (9%)
Query: 63 RFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLA 120
R + G G +S T PLD +K MQV + GI GF+ ++E G R L
Sbjct: 222 RHLVAGGGAGAVS----RTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLW 277
Query: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 180
+G L + + KF YE K ++G + L R L A + A A ++
Sbjct: 278 RGNGINVLKIAPESAIKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSI 332
Query: 181 APMEAAKVRIQTQP-GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 239
PME K R+ + G + + D A ++ EG+ AFYKG P + IPY + A +E
Sbjct: 333 YPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE 392
Query: 240 RTVEA-LYKFVVPKPRSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLN 292
A L + V + P V ++ G +A A+V + S+
Sbjct: 393 TLKNAWLQHYAV-----NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEG 447
Query: 293 KEKGSSASL---VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 338
+ + +SL +L+ G G+++GL + + ++ + +Y+++K+
Sbjct: 448 APEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 496
>gi|13994341 solute carrier family 25 member 2 [Homo sapiens]
Length = 301
Score = 74.7 bits (182), Expect = 1e-13
Identities = 68/272 (25%), Positives = 112/272 (41%), Gaps = 27/272 (9%)
Query: 66 ILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAP 125
+ G G +C T P D +K +MQ P YKG+ + F T + G+RG KG P
Sbjct: 13 LTAGAAGGTACVLTGQ---PFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGLRGFYKGTGP 69
Query: 126 TFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEA 185
+ Y + F Y + + G + AA + A FA +AL P E
Sbjct: 70 ALMAYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALCPTEL 129
Query: 186 AKVRIQTQ---------PGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFA 236
K R+QT NT+ + K++G FY G++ ++++P F
Sbjct: 130 VKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEVPGYFFFFG 189
Query: 237 CFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD------SVVSV 290
+E + F + + E V ++G +AG+ +V P D V+S+
Sbjct: 190 GYELSRSF---FASGRSKDELGP----VHLMLSGGVAGICLWLVVFPVDCIKSRIQVLSM 242
Query: 291 LNKEKGSSASL--VLKRLGFKGVWKGLFARII 320
K+ G +L V++ G ++ GL A +I
Sbjct: 243 YGKQAGFIGTLLSVVRNEGIVALYSGLKATMI 274
Score = 48.9 bits (115), Expect = 7e-06
Identities = 44/182 (24%), Positives = 70/182 (38%), Gaps = 6/182 (3%)
Query: 161 RTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGV 220
+ ++ L A A+ + P + KV++QT P L D K Y + GL+ FYKG
Sbjct: 8 QAAIDLTAGAAGGTACVLTGQPFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGLRGFYKGT 67
Query: 221 APLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIV 280
P M + + F C+ + + K +++ S + T AG A F A+
Sbjct: 68 GPALMAYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSD----LQTAAAGSFASAFAALA 123
Query: 281 SHPADSVVSVLNK--EKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 338
P + V L E S + V KG+ + +G L + V
Sbjct: 124 LCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEVPG 183
Query: 339 YF 340
YF
Sbjct: 184 YF 185
Score = 47.0 bits (110), Expect = 3e-05
Identities = 47/181 (25%), Positives = 74/181 (40%), Gaps = 22/181 (12%)
Query: 82 ALVPLDLVKCRMQVD---------PQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSM 132
AL P +LVKCR+Q + + I++ LK+DG G G + T L
Sbjct: 123 ALCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEVP 182
Query: 133 QGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQT 192
FG YE+ + +++ G L L L+ A + + P++ K RIQ
Sbjct: 183 GYFFFFGGYELSRSFFAS--GRSKDELGPVHLMLSGGV-AGICLWLVVFPVDCIKSRIQV 239
Query: 193 ------QPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALY 246
Q G+ TL + EG+ A Y G+ +R IP F +E + + +
Sbjct: 240 LSMYGKQAGFIGTLLSVV----RNEGIVALYSGLKATMIRAIPANGALFVAYEYSRKMMM 295
Query: 247 K 247
K
Sbjct: 296 K 296
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 73.2 bits (178), Expect = 3e-13
Identities = 60/261 (22%), Positives = 115/261 (44%), Gaps = 28/261 (10%)
Query: 97 PQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEEN 156
P ++G + F ++ +G++ L G PT + + F Y+ L + LGE
Sbjct: 81 PGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENE 140
Query: 157 TYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAF 216
T + + A A F A ++P+E + ++Q++ L K E+G +
Sbjct: 141 T-----CIPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISL 195
Query: 217 YKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVF 276
++G AP +R +P++ M + E L K++ K S +P ++ F +G ++G F
Sbjct: 196 WRGWAPTVLRDVPFSAM----YWYNYEILKKWLCEK--SGLYEP-TFMINFTSGALSGSF 248
Query: 277 CAIVSHPADSVVS------------VLNKEKGSSASLVLKRL----GFKGVWKGLFARII 320
A+ + P D V + ++ S +++K + GF G++ GL R+I
Sbjct: 249 AAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLI 308
Query: 321 MIGTLTALQWFIYDSVKVYFR 341
I A+ Y+ K +F+
Sbjct: 309 KIAPACAIMISTYEFGKAFFQ 329
Score = 50.8 bits (120), Expect = 2e-06
Identities = 43/212 (20%), Positives = 85/212 (40%), Gaps = 49/212 (23%)
Query: 166 LAASASAEFFADIALAPMEAAKVRIQTQ-------------------------------- 193
+ AS + + + P++ K+R+Q Q
Sbjct: 19 MLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKLWY 78
Query: 194 --PGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVP 251
PG DA K+ + EG+K+ + G+ P + +P T++ F C+++ L
Sbjct: 79 KKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALL------ 132
Query: 252 KPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL---VLKRL-- 306
RS+ + E + VAG +A V P + + + + +K S L V K++
Sbjct: 133 --RSKLGENE-TCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSE 189
Query: 307 -GFKGVWKGLFARIIMIGTLTALQWFIYDSVK 337
G+ +W+G ++ +A+ W+ Y+ +K
Sbjct: 190 DGWISLWRGWAPTVLRDVPFSAMYWYNYEILK 221
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/181 (22%), Positives = 74/181 (40%), Gaps = 15/181 (8%)
Query: 70 LGGIISCGTTHTALVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLG 129
+ GI++ T + PL+L++ +MQ Y + S + EDG L +GWAPT L
Sbjct: 146 VAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISLWRGWAPTVLR 205
Query: 130 YSMQGLCKFGFYEVFKVLYSNMLG-EENTYLWRTSLYLAASASAEFFADIALAPMEAAKV 188
+ YE+ K G E T++ + + A + FA +A P + K
Sbjct: 206 DVPFSAMYWYNYEILKKWLCEKSGLYEPTFM----INFTSGALSGSFAAVATLPFDVVKT 261
Query: 189 RIQTQPGYANTLRDAAP----------KMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACF 238
+ QTQ + + + P + + G + G+ P ++ P + + +
Sbjct: 262 QKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTY 321
Query: 239 E 239
E
Sbjct: 322 E 322
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 72.0 bits (175), Expect = 8e-13
Identities = 68/281 (24%), Positives = 122/281 (43%), Gaps = 23/281 (8%)
Query: 70 LGGIISCGTTHTALVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTF 127
+ G ++ + T PLD +K MQV K I G + E G+R L +G
Sbjct: 190 VAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINV 249
Query: 128 LGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAK 187
L + + KF YE K +LG++ T + + A A A + PME K
Sbjct: 250 LKIAPESAIKFMAYEQIK---RAILGQQETLHVQERFVAGSLAGAT--AQTIIYPMEVLK 304
Query: 188 VRIQ-TQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALY 246
R+ + G L D A ++ + EG +AFY+G P + IPY + A + E L
Sbjct: 305 TRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVY----ETLK 360
Query: 247 KFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNK----EKGSSASL- 301
+ + + + + P ++V G I+ I S+P V + + E G S+
Sbjct: 361 NWWLQQYSHDSADP-GILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSML 419
Query: 302 -----VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 337
+L + G +G+++G+ + + ++ + +Y+++K
Sbjct: 420 GLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMK 460
Score = 57.4 bits (137), Expect = 2e-08
Identities = 41/181 (22%), Positives = 79/181 (43%), Gaps = 6/181 (3%)
Query: 70 LGGIISCGTTHTALVPLDLVKCRMQVDPQ-KYKGIFNGFSVTLKEDGVRGLAKGWAPTFL 128
+ G ++ T T + P++++K R+ + +YKG+ + L+ +G R +G+ P L
Sbjct: 284 VAGSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVL 343
Query: 129 GYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKV 188
G YE K + ++ L LA + IA P+ +
Sbjct: 344 GIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVL-LACGTISSTCGQIASYPLALVRT 402
Query: 189 RIQTQP----GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEA 244
R+Q Q G ++ + +EG++ Y+G+AP +M+ IP + + +E +A
Sbjct: 403 RMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQA 462
Query: 245 L 245
L
Sbjct: 463 L 463
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 71.2 bits (173), Expect = 1e-12
Identities = 86/335 (25%), Positives = 135/335 (40%), Gaps = 51/335 (15%)
Query: 36 PTGQPRRPRNLAAAAVEEQYSCDYGSGRFFIL--------CGLGGIISCGTTHTALVPLD 87
P + P NLA A +++ S D S R +L GLG + TA+ P+D
Sbjct: 295 PLEEGTLPFNLAEAQRQQKASGD--SARPVLLQVAESAYRFGLGSVAGA-VGATAVYPID 351
Query: 88 LVKCRMQ--------VDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFG 139
LVK RMQ V YK F+ F L+ +G GL +G P LG + + K
Sbjct: 352 LVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLT 411
Query: 140 FYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFAD----IALAPMEAAKVRIQTQPG 195
+ + + + G S+ LAA A A I P+E K+R+Q
Sbjct: 412 VNDFVRDKFMHKDG---------SVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGE 462
Query: 196 YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRS 255
R +A + ++ G YKG ++R IP++ + F C+ A K
Sbjct: 463 ITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY-----AHVKASFANEDG 517
Query: 256 ECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL----------VLKR 305
+ S L +AG IAG+ A + PAD + + L + + +L+
Sbjct: 518 QVSPGSLL----LAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILRE 573
Query: 306 LGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYF 340
G K +WKG AR+ + Y+ ++ +F
Sbjct: 574 EGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWF 608
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 71.2 bits (173), Expect = 1e-12
Identities = 63/280 (22%), Positives = 109/280 (38%), Gaps = 33/280 (11%)
Query: 80 HTALVPLDLVKCRMQV---DPQ-KYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGL 135
H+ + P+D VK RMQ DP+ +Y I+ ++ +G +G +G
Sbjct: 60 HSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHA 119
Query: 136 CKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPG 195
F YE K +++ + + A + A D + P E K R+Q
Sbjct: 120 MYFACYENMKRTLNDVFHHQGNSHLANGI---AGSMATLLHDAVMNPAEVVKQRLQMYNS 176
Query: 196 YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRS 255
+ +++ EGL AFY+ IP+ + F +E E + P+S
Sbjct: 177 QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQS 236
Query: 256 ECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL-------------- 301
++G +AG A + P D ++LN ++ + SL
Sbjct: 237 H----------IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAF 286
Query: 302 --VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVY 339
V + G G +KG+ AR+I TA+ W +Y+ K +
Sbjct: 287 RTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYF 326
>gi|11225256 uncoupling protein 1 [Homo sapiens]
Length = 307
Score = 70.1 bits (170), Expect = 3e-12
Identities = 47/187 (25%), Positives = 88/187 (47%), Gaps = 15/187 (8%)
Query: 70 LGGIISCGTTHTALVPLDLVKCRMQVDPQ------KYKGIFNGFSVTLKEDGVRGLAKGW 123
L G+ + G P ++VK R+Q +Y G +N + + +G+ GL KG
Sbjct: 118 LAGLTTGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGT 177
Query: 124 APTFLGYSMQGLCKFGFYEVFKVLY--SNMLGEENTYLWRTSLYLAASASAEFFADIALA 181
P + + + Y++ K + +N+L ++ +L ++ A F A +
Sbjct: 178 TPNLMRSVIINCTELVTYDLMKEAFVKNNILADD------VPCHLVSALIAGFCATAMSS 231
Query: 182 PMEAAKVR-IQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER 240
P++ K R I + PG ++ + A K++ EG AF+KG+ P ++R + ++ F CFE+
Sbjct: 232 PVDVVKTRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQ 291
Query: 241 TVEALYK 247
L K
Sbjct: 292 LKRELSK 298
Score = 50.8 bits (120), Expect = 2e-06
Identities = 65/289 (22%), Positives = 102/289 (35%), Gaps = 39/289 (13%)
Query: 72 GIISCGTTHTALVPLDLVKCRMQVDPQ-------KYKGIFNGFSVTLKEDGVRGLAKGWA 124
GI +C PLD K R+QV + +YKG+ + +K +G L G
Sbjct: 21 GIAAC-LADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMKLYSGLP 79
Query: 125 PTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLY--LAASASAEFFADIALAP 182
+ G Y+ + + G+E + + L A F P
Sbjct: 80 AGLQRQISSASLRIGLYDTVQEFLT--AGKETAPSLGSKILAGLTTGGVAVFIGQ----P 133
Query: 183 MEAAKVRIQTQ-------PGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKF 235
E KVR+Q Q P Y T +A + EGL +KG P MR + +
Sbjct: 134 TEVVKVRLQAQSHLHGIKPRYTGTY-NAYRIIATTEGLTGLWKGTTPNLMRSVIINCTEL 192
Query: 236 ACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSV-VSVLNKE 294
++ EA K + C V+ IAG +S P D V +N
Sbjct: 193 VTYDLMKEAFVKNNILADDVPCH--------LVSALIAGFCATAMSSPVDVVKTRFINSP 244
Query: 295 KGSSASL------VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 337
G S+ V G +KGL + +G+ + + ++ +K
Sbjct: 245 PGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQLK 293
Score = 34.3 bits (77), Expect = 0.18
Identities = 40/195 (20%), Positives = 67/195 (34%), Gaps = 29/195 (14%)
Query: 166 LAASASAEFFADIALAPMEAAKVRIQTQPGYANT--------LRDAAPKMYKEEGLKAFY 217
L ++ A AD+ P++ AKVR+Q Q G T + + K EG Y
Sbjct: 17 LFSAGIAACLADVITFPLDTAKVRLQVQ-GECPTSSVIRYKGVLGTITAVVKTEGRMKLY 75
Query: 218 KGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFC 277
G+ RQI ++ ++ E L P L +AG G
Sbjct: 76 SGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAP--------SLGSKILAGLTTGGVA 127
Query: 278 AIVSHPADSVVSVLNKEKG------------SSASLVLKRLGFKGVWKGLFARIIMIGTL 325
+ P + V L + ++ ++ G G+WKG ++ +
Sbjct: 128 VFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVII 187
Query: 326 TALQWFIYDSVKVYF 340
+ YD +K F
Sbjct: 188 NCTELVTYDLMKEAF 202
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 69.7 bits (169), Expect = 4e-12
Identities = 75/294 (25%), Positives = 119/294 (40%), Gaps = 41/294 (13%)
Query: 69 GLGGIISCGTTHTALVPLDLVKCRMQ--------VDPQKYKGIFNGFSVTLKEDGVRGLA 120
GLG + TA+ P+DLVK RMQ V YK F+ F L+ +G GL
Sbjct: 333 GLGSVAGA-VGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 391
Query: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFAD--- 177
+G P LG + + K + + + + G S+ LAA A A
Sbjct: 392 RGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDG---------SVPLAAEILAGGCAGGSQ 442
Query: 178 -IALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFA 236
I P+E K+R+Q R +A + ++ G YKG ++R IP++ + F
Sbjct: 443 VIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFP 502
Query: 237 CFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKG 296
C+ A K + S L +AG IAG+ A + PAD + + L
Sbjct: 503 CY-----AHVKASFANEDGQVSPGSLL----LAGAIAGMPAASLVTPADVIKTRLQVAAR 553
Query: 297 SSASL----------VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYF 340
+ + +L+ G K +WKG AR+ + Y+ ++ +F
Sbjct: 554 AGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWF 607
>gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]
Length = 312
Score = 68.9 bits (167), Expect = 7e-12
Identities = 49/187 (26%), Positives = 82/187 (43%), Gaps = 13/187 (6%)
Query: 70 LGGIISCGTTHTALVPLDLVKCRMQVD--------PQKYKGIFNGFSVTLKEDGVRGLAK 121
L G + T P D+VK R Q +KY G + + +E+GVRGL K
Sbjct: 121 LAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWK 180
Query: 122 GWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALA 181
G P + ++ + Y++ K L + + + ++ A F A + +
Sbjct: 181 GTLPNIMRNAIVNCAEVVTYDILK----EKLLDYHLLTDNFPCHFVSAFGAGFCATVVAS 236
Query: 182 PMEAAKVR-IQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER 240
P++ K R + + PG + D KM +EG AFYKG P ++R + ++ F +E+
Sbjct: 237 PVDVVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQ 296
Query: 241 TVEALYK 247
AL K
Sbjct: 297 LKRALMK 303
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/194 (21%), Positives = 77/194 (39%), Gaps = 34/194 (17%)
Query: 169 SASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMY-----------KEEGLKAFY 217
+ +A FAD+ P++ AKVR+Q Q G ++ A Y + EG + Y
Sbjct: 20 AGTAACFADLVTFPLDTAKVRLQIQ-GENQAVQTARLVQYRGVLGTILTMVRTEGPCSPY 78
Query: 218 KGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFC 277
G+ RQ+ + ++ ++ +V+ +Y PK S L +AG G
Sbjct: 79 NGLVAGLQRQMSFASIRIGLYD-SVKQVY---TPKGADNSS----LTTRILAGCTTGAMA 130
Query: 278 AIVSHPADSV---------VSVLNKEKGSSASL-----VLKRLGFKGVWKGLFARIIMIG 323
+ P D V + ++ S ++ + + G +G+WKG I+
Sbjct: 131 VTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNA 190
Query: 324 TLTALQWFIYDSVK 337
+ + YD +K
Sbjct: 191 IVNCAEVVTYDILK 204
>gi|21361114 solute carrier family 25 (mitochondrial carrier;
oxoglutarate carrier), member 11 [Homo sapiens]
Length = 314
Score = 68.6 bits (166), Expect = 9e-12
Identities = 71/296 (23%), Positives = 124/296 (41%), Gaps = 37/296 (12%)
Query: 71 GGIISCGTTHTALVPLDLVKCRMQVDPQ-----KYKGIFNGFSVTLKEDGVRGLAKGWAP 125
GG+ G T + PLDLVK RMQ+ + +YK F+ + LK +G+RG+ G +
Sbjct: 28 GGLAGMGAT-VFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGLSA 86
Query: 126 TFLGYSMQGLCKFGFYEVFKVLYSNMLGEENT---YLWRTSLYLAASASAEFF---ADIA 179
L + + G Y VL+ + G + T +L + + + A A+ F A++A
Sbjct: 87 GLLRQATYTTTRLGIY---TVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVA 143
Query: 180 LAPMEA-AKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACF 238
L M A ++ + GY N +A ++ +EEG+ ++G P R + + A +
Sbjct: 144 LIRMTADGRLPADQRRGYKNVF-NALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASY 202
Query: 239 ERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSS 298
++ + L + ++ F A I+G+ S P D + + +
Sbjct: 203 SQSKQFLL--------DSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMID 254
Query: 299 AS-----------LVLKRLGFKGVWKGLFARIIMIGTLTALQW-FIYDSVKVYFRL 342
V++ GF +WKG +G T L + F+ K Y RL
Sbjct: 255 GKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRL 310
>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
Length = 318
Score = 67.0 bits (162), Expect = 2e-11
Identities = 52/170 (30%), Positives = 81/170 (47%), Gaps = 11/170 (6%)
Query: 77 GTTHTALV-PLDLVKCRMQVDPQK-YKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQG 134
GTT +L PLDLV+ RM V P++ Y IF+ F +E+G++ L G+ PT LG
Sbjct: 142 GTTAASLTYPLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYA 201
Query: 135 LCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASA----SAEFFADIALAPMEAAKVRI 190
F YE K L+ G Y + ++ A + SA + D+ M+ A V
Sbjct: 202 GLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTG 261
Query: 191 QTQPGYANTLRDAAPKMYKEEG-LKAFYKGVAPLWMRQIPYTMMKFACFE 239
+ A TLR + +EEG ++ YKG++ W++ + F F+
Sbjct: 262 YPRASIARTLR----TIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFD 307
Score = 45.4 bits (106), Expect = 8e-05
Identities = 45/188 (23%), Positives = 83/188 (44%), Gaps = 20/188 (10%)
Query: 166 LAASASAEFFADIALAPMEAAKV--RIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPL 223
L A A A A+AP++ K+ ++ ++ A Y EG + ++G +
Sbjct: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
Query: 224 WMRQIPYTMMKFAC---FERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIV 280
+R +PY ++F+ ++R + + Y F R E P AG +AG A +
Sbjct: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGF-----RGEALPPWP---RLFAGALAGTTAASL 148
Query: 281 SHPADSV---VSVLNKEKGSSASLVLKRL----GFKGVWKGLFARIIMIGTLTALQWFIY 333
++P D V ++V KE S+ V R+ G K ++ G ++ + L +F Y
Sbjct: 149 TYPLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTY 208
Query: 334 DSVKVYFR 341
+++K R
Sbjct: 209 ETLKSLHR 216
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 66.6 bits (161), Expect = 3e-11
Identities = 75/296 (25%), Positives = 120/296 (40%), Gaps = 31/296 (10%)
Query: 71 GGIISCGTTHTALVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFL 128
GGI C T + PLD VK +Q YK G+F+ +++G GL KG +
Sbjct: 43 GGIAGC-CAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGNGAMMI 101
Query: 129 GYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKV 188
G +F +E +K L + LG ++ R L A + A A I P++ +V
Sbjct: 102 RIFPYGAIQFMAFEHYKTLITTKLGISG-HVHR----LMAGSMAGMTAVICTYPLDMVRV 156
Query: 189 R----IQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEA 244
R ++ + Y + KE G FY+G+ P + PY + F F T+++
Sbjct: 157 RLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTF-GTLKS 215
Query: 245 LYKFVVPK--PRSECSKPEQLV----VTFVAGYIAGVFCAIVSHPAD---------SVVS 289
+ P R P LV V + G +AG +S+P D +V+
Sbjct: 216 VGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLP 275
Query: 290 VLNK--EKGSSASLVLKRLGF-KGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRL 342
K + V G KG+++GL I A+ + Y+ +K +F L
Sbjct: 276 EFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQFFHL 331
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,772,897
Number of Sequences: 37866
Number of extensions: 660270
Number of successful extensions: 2437
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 2053
Number of HSP's gapped (non-prelim): 173
length of query: 362
length of database: 18,247,518
effective HSP length: 104
effective length of query: 258
effective length of database: 14,309,454
effective search space: 3691839132
effective search space used: 3691839132
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.