Guide to the Human Genome
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Search of human proteins with 58743363

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58743363 centromere protein L isoform 2 [Homo sapiens]
         (344 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58743363 centromere protein L isoform 2 [Homo sapiens]             703   0.0  
gi|187608508 centromere protein L isoform 1 [Homo sapiens]            681   0.0  
gi|75677574 cell cycle progression 1 isoform 2 [Homo sapiens]          33   0.49 
gi|75677585 cell cycle progression 1 isoform 1 [Homo sapiens]          33   0.49 
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is...    30   2.4  
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     28   9.2  
gi|194473720 upstream of NRAS isoform 3 [Homo sapiens]                 28   9.2  
gi|56117852 upstream of NRAS isoform 1 [Homo sapiens]                  28   9.2  
gi|56117850 upstream of NRAS isoform 2 [Homo sapiens]                  28   9.2  

>gi|58743363 centromere protein L isoform 2 [Homo sapiens]
          Length = 344

 Score =  703 bits (1815), Expect = 0.0
 Identities = 344/344 (100%), Positives = 344/344 (100%)

Query: 1   MDSYSAPESTPSASSRPEDYFIGATPLQKRLESVRKQSSFILTPPRRKIPQCSQLQEDVD 60
           MDSYSAPESTPSASSRPEDYFIGATPLQKRLESVRKQSSFILTPPRRKIPQCSQLQEDVD
Sbjct: 1   MDSYSAPESTPSASSRPEDYFIGATPLQKRLESVRKQSSFILTPPRRKIPQCSQLQEDVD 60

Query: 61  PQKVAFLLHKQWTLYSLTPLYKFSYSNLKEYSRLLNAFIVAEKQKGLAVEVGEDFNIKVI 120
           PQKVAFLLHKQWTLYSLTPLYKFSYSNLKEYSRLLNAFIVAEKQKGLAVEVGEDFNIKVI
Sbjct: 61  PQKVAFLLHKQWTLYSLTPLYKFSYSNLKEYSRLLNAFIVAEKQKGLAVEVGEDFNIKVI 120

Query: 121 FSTLLGMKGTQRDPEAFLVQIVSKSQLPSENREGKVLWTGWFCCVFGDSLLETVSEDFTC 180
           FSTLLGMKGTQRDPEAFLVQIVSKSQLPSENREGKVLWTGWFCCVFGDSLLETVSEDFTC
Sbjct: 121 FSTLLGMKGTQRDPEAFLVQIVSKSQLPSENREGKVLWTGWFCCVFGDSLLETVSEDFTC 180

Query: 181 LPLFLANGAESNTAIIGTWFQKTFDCYFSPLAINAFNLSWMAAMWTACKMDHYVATTEFL 240
           LPLFLANGAESNTAIIGTWFQKTFDCYFSPLAINAFNLSWMAAMWTACKMDHYVATTEFL
Sbjct: 181 LPLFLANGAESNTAIIGTWFQKTFDCYFSPLAINAFNLSWMAAMWTACKMDHYVATTEFL 240

Query: 241 WSVPCSPQSLDISFAIHPEDAKALWDSVHKTPGEVTQEEVDLFMDCLYSHFHRHFKIHLS 300
           WSVPCSPQSLDISFAIHPEDAKALWDSVHKTPGEVTQEEVDLFMDCLYSHFHRHFKIHLS
Sbjct: 241 WSVPCSPQSLDISFAIHPEDAKALWDSVHKTPGEVTQEEVDLFMDCLYSHFHRHFKIHLS 300

Query: 301 ATRLVRVSTSVASAHTDGKIKILCHKYLIGVLAYLTELAIFQIE 344
           ATRLVRVSTSVASAHTDGKIKILCHKYLIGVLAYLTELAIFQIE
Sbjct: 301 ATRLVRVSTSVASAHTDGKIKILCHKYLIGVLAYLTELAIFQIE 344


>gi|187608508 centromere protein L isoform 1 [Homo sapiens]
          Length = 390

 Score =  681 bits (1758), Expect = 0.0
 Identities = 344/390 (88%), Positives = 344/390 (88%), Gaps = 46/390 (11%)

Query: 1   MDSYSAPESTPSASSRPEDYFIGATPLQKRLESVRKQSSFILTPPRRKIPQCSQLQEDVD 60
           MDSYSAPESTPSASSRPEDYFIGATPLQKRLESVRKQSSFILTPPRRKIPQCSQLQEDVD
Sbjct: 1   MDSYSAPESTPSASSRPEDYFIGATPLQKRLESVRKQSSFILTPPRRKIPQCSQLQEDVD 60

Query: 61  PQKVAFLLHKQWTLYSLTPLYKFSYSNLKEYSRLLNAFIVAEKQKGLAVEVGEDFNIKVI 120
           PQKVAFLLHKQWTLYSLTPLYKFSYSNLKEYSRLLNAFIVAEKQKGLAVEVGEDFNIKVI
Sbjct: 61  PQKVAFLLHKQWTLYSLTPLYKFSYSNLKEYSRLLNAFIVAEKQKGLAVEVGEDFNIKVI 120

Query: 121 FSTLLGMKGTQRDPEAFLVQ---------------------------------------- 140
           FSTLLGMKGTQRDPEAFLVQ                                        
Sbjct: 121 FSTLLGMKGTQRDPEAFLVQGLILSPRLEYSGTILVDCNLCLLGSSDPSTLAFQVAGTAG 180

Query: 141 ------IVSKSQLPSENREGKVLWTGWFCCVFGDSLLETVSEDFTCLPLFLANGAESNTA 194
                 IVSKSQLPSENREGKVLWTGWFCCVFGDSLLETVSEDFTCLPLFLANGAESNTA
Sbjct: 181 ACHHTRIVSKSQLPSENREGKVLWTGWFCCVFGDSLLETVSEDFTCLPLFLANGAESNTA 240

Query: 195 IIGTWFQKTFDCYFSPLAINAFNLSWMAAMWTACKMDHYVATTEFLWSVPCSPQSLDISF 254
           IIGTWFQKTFDCYFSPLAINAFNLSWMAAMWTACKMDHYVATTEFLWSVPCSPQSLDISF
Sbjct: 241 IIGTWFQKTFDCYFSPLAINAFNLSWMAAMWTACKMDHYVATTEFLWSVPCSPQSLDISF 300

Query: 255 AIHPEDAKALWDSVHKTPGEVTQEEVDLFMDCLYSHFHRHFKIHLSATRLVRVSTSVASA 314
           AIHPEDAKALWDSVHKTPGEVTQEEVDLFMDCLYSHFHRHFKIHLSATRLVRVSTSVASA
Sbjct: 301 AIHPEDAKALWDSVHKTPGEVTQEEVDLFMDCLYSHFHRHFKIHLSATRLVRVSTSVASA 360

Query: 315 HTDGKIKILCHKYLIGVLAYLTELAIFQIE 344
           HTDGKIKILCHKYLIGVLAYLTELAIFQIE
Sbjct: 361 HTDGKIKILCHKYLIGVLAYLTELAIFQIE 390


>gi|75677574 cell cycle progression 1 isoform 2 [Homo sapiens]
          Length = 757

 Score = 32.7 bits (73), Expect = 0.49
 Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 6/117 (5%)

Query: 20  YFIGATPLQKRLESVRKQSSFILTPPRRKIPQCSQLQED-VDPQKVAFLLHKQWTLYSLT 78
           +F G   +QKR + VRK     L   +  + QC Q QE  +D + +   L + WT   LT
Sbjct: 233 HFYGTIQIQKRQQLVRKIHEDELNDMKDYLSQCQQEQESFIDYKSLKENLARCWT---LT 289

Query: 79  PLYKFSYSNLKEYSRLLNAF--IVAEKQKGLAVEVGEDFNIKVIFSTLLGMKGTQRD 133
              K S+   K      N +  +  EK++     + E+ N       +L  KGT  +
Sbjct: 290 EAEKMSFETQKTNLATENQYLRVSLEKEEKALSSLQEELNKLREQIRILEDKGTSTE 346


>gi|75677585 cell cycle progression 1 isoform 1 [Homo sapiens]
          Length = 757

 Score = 32.7 bits (73), Expect = 0.49
 Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 6/117 (5%)

Query: 20  YFIGATPLQKRLESVRKQSSFILTPPRRKIPQCSQLQED-VDPQKVAFLLHKQWTLYSLT 78
           +F G   +QKR + VRK     L   +  + QC Q QE  +D + +   L + WT   LT
Sbjct: 233 HFYGTIQIQKRQQLVRKIHEDELNDMKDYLSQCQQEQESFIDYKSLKENLARCWT---LT 289

Query: 79  PLYKFSYSNLKEYSRLLNAF--IVAEKQKGLAVEVGEDFNIKVIFSTLLGMKGTQRD 133
              K S+   K      N +  +  EK++     + E+ N       +L  KGT  +
Sbjct: 290 EAEKMSFETQKTNLATENQYLRVSLEKEEKALSSLQEELNKLREQIRILEDKGTSTE 346


>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
            2 [Homo sapiens]
          Length = 2466

 Score = 30.4 bits (67), Expect = 2.4
 Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 1/83 (1%)

Query: 30   RLESVRKQSSFILTPPRRKIPQCSQLQEDVDPQKVAFLLHKQWTLYSLTPLYKFSYSNLK 89
            +L + +  +S   +P RRK    S   ED     V  +LHK+W++ S +P  + +  NLK
Sbjct: 1020 KLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLDVLHKRWSIVS-SPEREITLVNLK 1078

Query: 90   EYSRLLNAFIVAEKQKGLAVEVG 112
            + ++    F +   +K   +++G
Sbjct: 1079 KDAKYGLGFQIIGGEKMGRLDLG 1101


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 28.5 bits (62), Expect = 9.2
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 18/75 (24%)

Query: 2    DSYSAPESTPSASSRPEDYFIGATPLQKRLESVRKQSSFILTPP-RRKIP--QCSQLQED 58
            D Y A +   + S RP+DY + AT     L+S+  Q   +LTP   RK P   C  L+  
Sbjct: 1115 DFYRADQPRSAPSLRPKDYEVDAT-----LKSLNNQIETLLTPEGSRKNPARTCRDLR-- 1167

Query: 59   VDPQKVAFLLHKQWT 73
                    L H +W+
Sbjct: 1168 --------LSHPEWS 1174


>gi|194473720 upstream of NRAS isoform 3 [Homo sapiens]
          Length = 813

 Score = 28.5 bits (62), Expect = 9.2
 Identities = 21/84 (25%), Positives = 35/84 (41%), Gaps = 9/84 (10%)

Query: 52  CSQLQEDVDPQKVAFLLHKQWTLYSLTPLYKFSYSNLKEYSRLLN---------AFIVAE 102
           C Q  E V  Q      + Q   Y++TPL + +   +K+    +N          F V E
Sbjct: 660 CLQKGESVKFQLCVLGQNAQTMAYNITPLRRATVECVKDQFGFINYEVGDSKKLFFHVKE 719

Query: 103 KQKGLAVEVGEDFNIKVIFSTLLG 126
            Q G+ ++ G++    VI +   G
Sbjct: 720 VQDGIELQAGDEVEFSVILNQRTG 743


>gi|56117852 upstream of NRAS isoform 1 [Homo sapiens]
          Length = 798

 Score = 28.5 bits (62), Expect = 9.2
 Identities = 21/84 (25%), Positives = 35/84 (41%), Gaps = 9/84 (10%)

Query: 52  CSQLQEDVDPQKVAFLLHKQWTLYSLTPLYKFSYSNLKEYSRLLN---------AFIVAE 102
           C Q  E V  Q      + Q   Y++TPL + +   +K+    +N          F V E
Sbjct: 645 CLQKGESVKFQLCVLGQNAQTMAYNITPLRRATVECVKDQFGFINYEVGDSKKLFFHVKE 704

Query: 103 KQKGLAVEVGEDFNIKVIFSTLLG 126
            Q G+ ++ G++    VI +   G
Sbjct: 705 VQDGIELQAGDEVEFSVILNQRTG 728


>gi|56117850 upstream of NRAS isoform 2 [Homo sapiens]
          Length = 767

 Score = 28.5 bits (62), Expect = 9.2
 Identities = 21/84 (25%), Positives = 35/84 (41%), Gaps = 9/84 (10%)

Query: 52  CSQLQEDVDPQKVAFLLHKQWTLYSLTPLYKFSYSNLKEYSRLLN---------AFIVAE 102
           C Q  E V  Q      + Q   Y++TPL + +   +K+    +N          F V E
Sbjct: 614 CLQKGESVKFQLCVLGQNAQTMAYNITPLRRATVECVKDQFGFINYEVGDSKKLFFHVKE 673

Query: 103 KQKGLAVEVGEDFNIKVIFSTLLG 126
            Q G+ ++ G++    VI +   G
Sbjct: 674 VQDGIELQAGDEVEFSVILNQRTG 697


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.134    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,310,651
Number of Sequences: 37866
Number of extensions: 560697
Number of successful extensions: 1328
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1325
Number of HSP's gapped (non-prelim): 10
length of query: 344
length of database: 18,247,518
effective HSP length: 103
effective length of query: 241
effective length of database: 14,347,320
effective search space: 3457704120
effective search space used: 3457704120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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