Guide to the Human Genome
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Search of human proteins with 58219054

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58219054 pro-apoptotic Bcl-2 protein [Homo sapiens]
         (163 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58219054 pro-apoptotic Bcl-2 protein [Homo sapiens]                323   4e-89
gi|10835103 interferon, alpha 4 [Homo sapiens]                         31   0.54 
gi|4504589 interferon, alpha 10 [Homo sapiens]                         31   0.54 
gi|10880985 interferon, alpha 17 [Homo sapiens]                        30   0.92 
gi|71143135 interferon, alpha 7 [Homo sapiens]                         29   1.6  
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                28   2.7  
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    28   4.6  
gi|178056552 non-SMC condensin I complex, subunit D2 [Homo sapiens]    28   4.6  
gi|21361796 ELL associated factor 2 [Homo sapiens]                     27   7.8  

>gi|58219054 pro-apoptotic Bcl-2 protein [Homo sapiens]
          Length = 163

 Score =  323 bits (828), Expect = 4e-89
 Identities = 163/163 (100%), Positives = 163/163 (100%)

Query: 1   MKSSQTFEEQTECIVNTLLMDFLSPTLQVASRNLCCVDEVDSGEPCSFDVAIIAGRLRML 60
           MKSSQTFEEQTECIVNTLLMDFLSPTLQVASRNLCCVDEVDSGEPCSFDVAIIAGRLRML
Sbjct: 1   MKSSQTFEEQTECIVNTLLMDFLSPTLQVASRNLCCVDEVDSGEPCSFDVAIIAGRLRML 60

Query: 61  GDQFNGELEASAKNVIAETIKGQTGAILQDTVESLSKTWCAQDSSLAYERAFLAVSVKLL 120
           GDQFNGELEASAKNVIAETIKGQTGAILQDTVESLSKTWCAQDSSLAYERAFLAVSVKLL
Sbjct: 61  GDQFNGELEASAKNVIAETIKGQTGAILQDTVESLSKTWCAQDSSLAYERAFLAVSVKLL 120

Query: 121 EYMAHIAPEVVGQVAIPMTGMINGNQAIREFIQGQGGWENLES 163
           EYMAHIAPEVVGQVAIPMTGMINGNQAIREFIQGQGGWENLES
Sbjct: 121 EYMAHIAPEVVGQVAIPMTGMINGNQAIREFIQGQGGWENLES 163


>gi|10835103 interferon, alpha 4 [Homo sapiens]
          Length = 189

 Score = 30.8 bits (68), Expect = 0.54
 Identities = 18/76 (23%), Positives = 41/76 (53%), Gaps = 3/76 (3%)

Query: 81  KGQTGAILQDTVESLSKTWCAQDSSLAYERAFL-AVSVKLLEYMAHIAPEVVGQVAIPMT 139
           K Q  ++L + ++     +  +DSS A+E++ L   S +L + +  +   V+ +V +  T
Sbjct: 73  KAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVGVEET 132

Query: 140 GMINGNQ--AIREFIQ 153
            ++N +   A+R++ Q
Sbjct: 133 PLMNEDSILAVRKYFQ 148


>gi|4504589 interferon, alpha 10 [Homo sapiens]
          Length = 189

 Score = 30.8 bits (68), Expect = 0.54
 Identities = 18/76 (23%), Positives = 41/76 (53%), Gaps = 3/76 (3%)

Query: 81  KGQTGAILQDTVESLSKTWCAQDSSLAYERAFL-AVSVKLLEYMAHIAPEVVGQVAIPMT 139
           K Q  ++L + ++     +  +DSS A+E++ L   S +L + +  +   V+ +V +  T
Sbjct: 73  KAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVGVEET 132

Query: 140 GMINGNQ--AIREFIQ 153
            ++N +   A+R++ Q
Sbjct: 133 PLMNEDSILAVRKYFQ 148


>gi|10880985 interferon, alpha 17 [Homo sapiens]
          Length = 189

 Score = 30.0 bits (66), Expect = 0.92
 Identities = 18/76 (23%), Positives = 42/76 (55%), Gaps = 3/76 (3%)

Query: 81  KGQTGAILQDTVESLSKTWCAQDSSLAYERAFL-AVSVKLLEYMAHIAPEVVGQVAIPMT 139
           K Q  ++L + ++     +  +DSS A+E++ L   S +L + + ++   V+ +V +  T
Sbjct: 73  KTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLEACVIQEVGMEET 132

Query: 140 GMINGNQ--AIREFIQ 153
            ++N +   A+R++ Q
Sbjct: 133 PLMNEDSILAVRKYFQ 148


>gi|71143135 interferon, alpha 7 [Homo sapiens]
          Length = 189

 Score = 29.3 bits (64), Expect = 1.6
 Identities = 18/76 (23%), Positives = 41/76 (53%), Gaps = 3/76 (3%)

Query: 81  KGQTGAILQDTVESLSKTWCAQDSSLAYERAFL-AVSVKLLEYMAHIAPEVVGQVAIPMT 139
           K Q  ++L + ++     +  +DSS A+E++ L   S +L + +  +   V+ +V +  T
Sbjct: 73  KTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVGVEET 132

Query: 140 GMINGN--QAIREFIQ 153
            ++N +   A+R++ Q
Sbjct: 133 PLMNEDFILAVRKYFQ 148


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 28.5 bits (62), Expect = 2.7
 Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 6/79 (7%)

Query: 38   DEVDSGEPCSFDVAIIAGRLRMLGDQFNGELE--ASAKNVIAETIKGQTGAILQDTVESL 95
            D VDS +    D  + AG L++  ++ NG L     ++  + + ++G T A+ Q +  SL
Sbjct: 1684 DRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSA-SL 1742

Query: 96   SKTWCAQDSSLAYERAFLA 114
            + T   +D +L  ++A  A
Sbjct: 1743 NST---RDKNLHLQKALTA 1758


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
            region 1 [Homo sapiens]
          Length = 1400

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 1/82 (1%)

Query: 72   AKNVIAETIKGQTGAILQDTVESLSKTWCAQDSSLAYERAFLAVSVKLLEYMAHIAPEVV 131
            AK   A      +  + Q+T++S++K+    DS++A +   L+  V +   +   APE  
Sbjct: 1317 AKTTTASVSTTASTTLYQNTIDSVAKSVPTMDSTIASKSTTLSKIVSVPTAVFIKAPETT 1376

Query: 132  GQVAIPMTGMI-NGNQAIREFI 152
                I +  +I +G  A+ ++I
Sbjct: 1377 TGSEITLASIITSGTTAVCDYI 1398


>gi|178056552 non-SMC condensin I complex, subunit D2 [Homo sapiens]
          Length = 1401

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 17/125 (13%)

Query: 2    KSSQTFEEQTECIVNT-LLMDFLSPTLQVASRNLCCVDEVDSGEPCSFDVAIIAGRLRML 60
            ++SQ   +++  ++ T LLM+ LS    VA + L  +++  SGE C         R R+L
Sbjct: 905  RTSQEDPKESPAMLPTFLLMNLLSLAGDVALQQLVHLEQAVSGELC---------RRRVL 955

Query: 61   -GDQFNGELEASAKNVIAETIK----GQTGAILQDTVESLSKTWCAQDSSLAYERAFLAV 115
              +Q +   +   KN  +ET      G  GA   DT   L +  C  +  L   +  LA 
Sbjct: 956  REEQEHKTKDPKEKNTSSETTMEEELGLVGATADDTEAELIRGIC--EMELLDGKQTLAA 1013

Query: 116  SVKLL 120
             V LL
Sbjct: 1014 FVPLL 1018


>gi|21361796 ELL associated factor 2 [Homo sapiens]
          Length = 260

 Score = 26.9 bits (58), Expect = 7.8
 Identities = 15/55 (27%), Positives = 26/55 (47%), Gaps = 3/55 (5%)

Query: 1  MKSSQTFEEQTECIVNTLLMDFLSPTLQVASRNLCCVDEVDSGEPCSFDVAIIAG 55
          +K  ++FE+Q  C  +T+  DF   ++  +S       EV  GE  +  +  I G
Sbjct: 17 LKLGESFEKQPRCAFHTVRYDFKPASIDTSSEGYL---EVGEGEQVTITLPNIEG 68


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,065,452
Number of Sequences: 37866
Number of extensions: 177771
Number of successful extensions: 321
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 319
Number of HSP's gapped (non-prelim): 10
length of query: 163
length of database: 18,247,518
effective HSP length: 94
effective length of query: 69
effective length of database: 14,688,114
effective search space: 1013479866
effective search space used: 1013479866
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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