Guide to the Human Genome
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Search of human proteins with 57527756

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|57527756 hypothetical protein LOC54953 [Homo sapiens]
         (454 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|57527756 hypothetical protein LOC54953 [Homo sapiens]              907   0.0  
gi|16445438 bromodomain and WD repeat domain containing 1 isofor...    30   4.5  
gi|16445436 bromodomain and WD repeat domain containing 1 isofor...    30   4.5  
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 30   5.9  
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    30   5.9  
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    30   5.9  
gi|116686122 kinesin family member 4 [Homo sapiens]                    30   5.9  
gi|167466262 zinc finger, CCHC domain containing 16 [Homo sapiens]     29   7.7  

>gi|57527756 hypothetical protein LOC54953 [Homo sapiens]
          Length = 454

 Score =  907 bits (2344), Expect = 0.0
 Identities = 454/454 (100%), Positives = 454/454 (100%)

Query: 1   MGRTYIVEETVGQYLSNINLQGKAFVSGLLIGQCSSQKDYVILATRTPPKEEQSENLKHP 60
           MGRTYIVEETVGQYLSNINLQGKAFVSGLLIGQCSSQKDYVILATRTPPKEEQSENLKHP
Sbjct: 1   MGRTYIVEETVGQYLSNINLQGKAFVSGLLIGQCSSQKDYVILATRTPPKEEQSENLKHP 60

Query: 61  KAKLDNLDEEWATEHACQVSRMLPGGLLVLGVFIITTLELANDFQNALRRLMFAVEKSIN 120
           KAKLDNLDEEWATEHACQVSRMLPGGLLVLGVFIITTLELANDFQNALRRLMFAVEKSIN
Sbjct: 61  KAKLDNLDEEWATEHACQVSRMLPGGLLVLGVFIITTLELANDFQNALRRLMFAVEKSIN 120

Query: 121 RKRLWNFTEEEVSERVTLHICASTKKIFCRTYDIHDPKSSARPADWKYQSGLSSSWLSLE 180
           RKRLWNFTEEEVSERVTLHICASTKKIFCRTYDIHDPKSSARPADWKYQSGLSSSWLSLE
Sbjct: 121 RKRLWNFTEEEVSERVTLHICASTKKIFCRTYDIHDPKSSARPADWKYQSGLSSSWLSLE 180

Query: 181 CTVHINIHIPLSATSVSYTLEKNTKNGLTRWAKEIENGVYLINGQVKDEDCDLLEGQKKS 240
           CTVHINIHIPLSATSVSYTLEKNTKNGLTRWAKEIENGVYLINGQVKDEDCDLLEGQKKS
Sbjct: 181 CTVHINIHIPLSATSVSYTLEKNTKNGLTRWAKEIENGVYLINGQVKDEDCDLLEGQKKS 240

Query: 241 SRGNTQATSHSFDVRVLTQLLLNSDHRSTATVQICSGSVNLKGAVKCRAYIHSSKPKVKD 300
           SRGNTQATSHSFDVRVLTQLLLNSDHRSTATVQICSGSVNLKGAVKCRAYIHSSKPKVKD
Sbjct: 241 SRGNTQATSHSFDVRVLTQLLLNSDHRSTATVQICSGSVNLKGAVKCRAYIHSSKPKVKD 300

Query: 301 AVQAVKRDILNTVADRCEMLFEDLLLNEIPEKKDSEKEFHVLPYRVFVPLPGSTVMLCDY 360
           AVQAVKRDILNTVADRCEMLFEDLLLNEIPEKKDSEKEFHVLPYRVFVPLPGSTVMLCDY
Sbjct: 301 AVQAVKRDILNTVADRCEMLFEDLLLNEIPEKKDSEKEFHVLPYRVFVPLPGSTVMLCDY 360

Query: 361 KFDDESAEEIRDHFMEMLDHTIQIEDLEIAEETNTACMSSSMNSQASLDNTDDEQPKQPI 420
           KFDDESAEEIRDHFMEMLDHTIQIEDLEIAEETNTACMSSSMNSQASLDNTDDEQPKQPI
Sbjct: 361 KFDDESAEEIRDHFMEMLDHTIQIEDLEIAEETNTACMSSSMNSQASLDNTDDEQPKQPI 420

Query: 421 KTTMLLKIQQNIGVIAAFTVAVLAAGISFHYFSD 454
           KTTMLLKIQQNIGVIAAFTVAVLAAGISFHYFSD
Sbjct: 421 KTTMLLKIQQNIGVIAAFTVAVLAAGISFHYFSD 454


>gi|16445438 bromodomain and WD repeat domain containing 1 isoform B
            [Homo sapiens]
          Length = 2269

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 46/214 (21%), Positives = 89/214 (41%), Gaps = 28/214 (13%)

Query: 213  KEIENGVYLINGQVKDEDCDLLEGQKKSSRGNTQATSHSFDVRVLTQLLLNSDHRSTAT- 271
            + I NG  L   +V+D     L     SS   ++ +S + +    + L  +S+ R T T 
Sbjct: 1519 RPITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLSRSSNLRVTRTR 1578

Query: 272  -VQICSGSVNL-----KGAVKCRAYIHSSKPKVKDAVQAVKRDILNT--VADRCEMLFED 323
              Q  +G V+L     + A + R Y+  S     +  + +K    N   V  +C  +  +
Sbjct: 1579 AAQRKTGPVSLANGCGRKATRKRVYLSDSDNNSLETGEILKARAGNNRKVLRKCAAVAAN 1638

Query: 324  L--LLNEIPEKKDSEK--EFHVLPYRVFVPLPGSTVMLCDYKFDDESAEEIRDHFMEMLD 379
               L++++ E   SE       LP+R       S V       + E  + ++        
Sbjct: 1639 KIKLMSDVEENSSSESVCSGRKLPHR-----NASAVARKKLLHNSEDEQSLKS------- 1686

Query: 380  HTIQIEDLEIAEETNTACMSSSMNSQASLDNTDD 413
               +IE+ E+ +E     +SSS  +Q+++D +++
Sbjct: 1687 ---EIEEEELKDENQLLPVSSSHTAQSNVDESEN 1717



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 62/286 (21%), Positives = 104/286 (36%), Gaps = 52/286 (18%)

Query: 114  AVEKSINRKRLWNFTEEEVSERVTLHICASTKKIFCRTYDIHDPKSSARPADWKYQSGLS 173
            + E S  RKR    T         +    +T      +    + K S+R  +   +SGLS
Sbjct: 1508 SAESSERRKRNRPITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLS 1567

Query: 174  SSWLSLECTVHINIHIPLSATSVSYTLEKNTKNGLTRWAKEIENGVYLINGQVKDEDCDL 233
             S          N+ +  +  +   T   +  NG  R  K     VYL      D D + 
Sbjct: 1568 RS---------SNLRVTRTRAAQRKTGPVSLANGCGR--KATRKRVYL-----SDSDNNS 1611

Query: 234  LEGQK--KSSRGNTQATSHSFDVRVLTQLLLNSD-HRSTATVQICSGSV---NLKGAVKC 287
            LE  +  K+  GN +            ++ L SD   ++++  +CSG         AV  
Sbjct: 1612 LETGEILKARAGNNRKVLRKCAAVAANKIKLMSDVEENSSSESVCSGRKLPHRNASAVAR 1671

Query: 288  RAYIHSSKPKVKDAVQAVKRDILNTVADRCEMLFEDLLLN-----------EIPEKKDSE 336
            +  +H+S+ +     Q++K +I     +  E+  E+ LL            +  E +DSE
Sbjct: 1672 KKLLHNSEDE-----QSLKSEI-----EEEELKDENQLLPVSSSHTAQSNVDESENRDSE 1721

Query: 337  KE---------FHVLPYRVFVPLPGSTVMLCDYKFDDESAEEIRDH 373
             E         +H   Y+   P P  T  L     +++S     DH
Sbjct: 1722 SESDLRVARKNWHANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDH 1767


>gi|16445436 bromodomain and WD repeat domain containing 1 isoform A
            [Homo sapiens]
          Length = 2320

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 46/214 (21%), Positives = 89/214 (41%), Gaps = 28/214 (13%)

Query: 213  KEIENGVYLINGQVKDEDCDLLEGQKKSSRGNTQATSHSFDVRVLTQLLLNSDHRSTAT- 271
            + I NG  L   +V+D     L     SS   ++ +S + +    + L  +S+ R T T 
Sbjct: 1519 RPITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLSRSSNLRVTRTR 1578

Query: 272  -VQICSGSVNL-----KGAVKCRAYIHSSKPKVKDAVQAVKRDILNT--VADRCEMLFED 323
              Q  +G V+L     + A + R Y+  S     +  + +K    N   V  +C  +  +
Sbjct: 1579 AAQRKTGPVSLANGCGRKATRKRVYLSDSDNNSLETGEILKARAGNNRKVLRKCAAVAAN 1638

Query: 324  L--LLNEIPEKKDSEK--EFHVLPYRVFVPLPGSTVMLCDYKFDDESAEEIRDHFMEMLD 379
               L++++ E   SE       LP+R       S V       + E  + ++        
Sbjct: 1639 KIKLMSDVEENSSSESVCSGRKLPHR-----NASAVARKKLLHNSEDEQSLKS------- 1686

Query: 380  HTIQIEDLEIAEETNTACMSSSMNSQASLDNTDD 413
               +IE+ E+ +E     +SSS  +Q+++D +++
Sbjct: 1687 ---EIEEEELKDENQLLPVSSSHTAQSNVDESEN 1717



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 62/286 (21%), Positives = 104/286 (36%), Gaps = 52/286 (18%)

Query: 114  AVEKSINRKRLWNFTEEEVSERVTLHICASTKKIFCRTYDIHDPKSSARPADWKYQSGLS 173
            + E S  RKR    T         +    +T      +    + K S+R  +   +SGLS
Sbjct: 1508 SAESSERRKRNRPITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLS 1567

Query: 174  SSWLSLECTVHINIHIPLSATSVSYTLEKNTKNGLTRWAKEIENGVYLINGQVKDEDCDL 233
             S          N+ +  +  +   T   +  NG  R  K     VYL      D D + 
Sbjct: 1568 RS---------SNLRVTRTRAAQRKTGPVSLANGCGR--KATRKRVYL-----SDSDNNS 1611

Query: 234  LEGQK--KSSRGNTQATSHSFDVRVLTQLLLNSD-HRSTATVQICSGSV---NLKGAVKC 287
            LE  +  K+  GN +            ++ L SD   ++++  +CSG         AV  
Sbjct: 1612 LETGEILKARAGNNRKVLRKCAAVAANKIKLMSDVEENSSSESVCSGRKLPHRNASAVAR 1671

Query: 288  RAYIHSSKPKVKDAVQAVKRDILNTVADRCEMLFEDLLLN-----------EIPEKKDSE 336
            +  +H+S+ +     Q++K +I     +  E+  E+ LL            +  E +DSE
Sbjct: 1672 KKLLHNSEDE-----QSLKSEI-----EEEELKDENQLLPVSSSHTAQSNVDESENRDSE 1721

Query: 337  KE---------FHVLPYRVFVPLPGSTVMLCDYKFDDESAEEIRDH 373
             E         +H   Y+   P P  T  L     +++S     DH
Sbjct: 1722 SESDLRVARKNWHANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDH 1767


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 26/133 (19%), Positives = 58/133 (43%), Gaps = 2/133 (1%)

Query: 195  SVSYTLEKNTKNGLTRWAKEIENGVYLINGQVKDEDC--DLLEGQKKSSRGNTQATSHSF 252
            ++   L++N ++ + +   E+E+  YL++   K+  C    L+ QK+++      T  + 
Sbjct: 1667 NIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNL 1726

Query: 253  DVRVLTQLLLNSDHRSTATVQICSGSVNLKGAVKCRAYIHSSKPKVKDAVQAVKRDILNT 312
              R+ +QL L    +   +  +      +  A + R    +S+ +    VQ +       
Sbjct: 1727 VERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRE 1786

Query: 313  VADRCEMLFEDLL 325
            +  + E L E+LL
Sbjct: 1787 LKTQVEDLNENLL 1799


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 18/79 (22%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 346  VFVPLPGSTVMLCDYKFDDESAEEIRDHFMEMLDHTIQ------IEDLEIAEETNTACMS 399
            V  PL   ++M  DY     S  E  D + ++L+H +Q        D    E+ +++C+ 
Sbjct: 1094 VLRPLQEESIMEKDYSASINSLLERYDTYRDILEHHLQNNKFRITSDFSSEEDRSSSCLQ 1153

Query: 400  SSMNSQASLDNTDDEQPKQ 418
            + +     + N  D + K+
Sbjct: 1154 AKLTDLQVIKNETDARWKE 1172


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
            [Homo sapiens]
          Length = 6885

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 18/79 (22%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 346  VFVPLPGSTVMLCDYKFDDESAEEIRDHFMEMLDHTIQ------IEDLEIAEETNTACMS 399
            V  PL   ++M  DY     S  E  D + ++L+H +Q        D    E+ +++C+ 
Sbjct: 1094 VLRPLQEESIMEKDYSASINSLLERYDTYRDILEHHLQNNKFRITSDFSSEEDRSSSCLQ 1153

Query: 400  SSMNSQASLDNTDDEQPKQ 418
            + +     + N  D + K+
Sbjct: 1154 AKLTDLQVIKNETDARWKE 1172


>gi|116686122 kinesin family member 4 [Homo sapiens]
          Length = 1232

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 14/85 (16%)

Query: 350  LPGSTVMLCDYKFD----DESAEEIRDHFMEMLDHTIQIEDLEIAEETNTACMSSSMNSQ 405
            LP  T++  D  F+          +++ F+E    ++ IEDL+        C   S+N  
Sbjct: 1006 LPKDTLLSPDSSFEYVPPKPKPSRVKEKFLEQ---SMDIEDLKY-------CSEHSVNEH 1055

Query: 406  ASLDNTDDEQPKQPIKTTMLLKIQQ 430
               D  DDE   +  K T L+K+ +
Sbjct: 1056 EDGDGDDDEGDDEEWKPTKLVKVSR 1080


>gi|167466262 zinc finger, CCHC domain containing 16 [Homo sapiens]
          Length = 310

 Score = 29.3 bits (64), Expect = 7.7
 Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 6/71 (8%)

Query: 357 LCDYKFDDESAEEIRDHFMEMLDHTIQIEDLE------IAEETNTACMSSSMNSQASLDN 410
           L D   D+ES  ++ D+  +++   IQ++         +  ET    ++S +  QA    
Sbjct: 188 LADPNQDEESVTDMMDNLPDLITQCIQLDKKHSDRPELLQSETQLPLLASLIQHQALFSP 247

Query: 411 TDDEQPKQPIK 421
           TD    K PI+
Sbjct: 248 TDPPPKKGPIQ 258


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,467,202
Number of Sequences: 37866
Number of extensions: 691952
Number of successful extensions: 1982
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1971
Number of HSP's gapped (non-prelim): 16
length of query: 454
length of database: 18,247,518
effective HSP length: 106
effective length of query: 348
effective length of database: 14,233,722
effective search space: 4953335256
effective search space used: 4953335256
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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