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Search of human proteins with 55750011
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55750011 deiodinase, iodothyronine, type III [Homo sapiens]
(278 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55750011 deiodinase, iodothyronine, type III [Homo sapiens] 572 e-163
gi|4557522 deiodinase, iodothyronine, type I isoform a [Homo sap... 154 1e-37
gi|7549803 deiodinase, iodothyronine, type II isoform a [Homo sa... 152 3e-37
gi|7549805 deiodinase, iodothyronine, type II isoform a [Homo sa... 152 3e-37
gi|55749998 deiodinase, iodothyronine, type II isoform b [Homo s... 139 3e-33
gi|47132603 deiodinase, iodothyronine, type I isoform b [Homo sa... 138 5e-33
gi|89357938 deiodinase, iodothyronine, type I isoform d [Homo sa... 82 4e-16
gi|89357935 deiodinase, iodothyronine, type I isoform c [Homo sa... 76 3e-14
gi|117190519 sialidase 3 [Homo sapiens] 30 1.8
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 29 5.2
>gi|55750011 deiodinase, iodothyronine, type III [Homo sapiens]
Length = 278
Score = 572 bits (1474), Expect = e-163
Identities = 278/278 (100%), Positives = 278/278 (100%)
Query: 1 MLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLWLLDFLCIRKHFLGRRRRGQPEPEVEL 60
MLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLWLLDFLCIRKHFLGRRRRGQPEPEVEL
Sbjct: 1 MLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLWLLDFLCIRKHFLGRRRRGQPEPEVEL 60
Query: 61 NSEGEEVPPDDPPICVSDDNRLCTLASLKAVWHGQKLDFFKQAHEGGPAPNSEVVLPDGF 120
NSEGEEVPPDDPPICVSDDNRLCTLASLKAVWHGQKLDFFKQAHEGGPAPNSEVVLPDGF
Sbjct: 61 NSEGEEVPPDDPPICVSDDNRLCTLASLKAVWHGQKLDFFKQAHEGGPAPNSEVVLPDGF 120
Query: 121 QSQHILDYAQGNRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDG 180
QSQHILDYAQGNRPLVLNFGSCT PPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDG
Sbjct: 121 QSQHILDYAQGNRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDG 180
Query: 181 WVTTDSPYIIPQHRSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVIQS 240
WVTTDSPYIIPQHRSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVIQS
Sbjct: 181 WVTTDSPYIIPQHRSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVIQS 240
Query: 241 GTIMYQGGRGPDGYQVSELRTWLERYDEQLHGARPRRV 278
GTIMYQGGRGPDGYQVSELRTWLERYDEQLHGARPRRV
Sbjct: 241 GTIMYQGGRGPDGYQVSELRTWLERYDEQLHGARPRRV 278
>gi|4557522 deiodinase, iodothyronine, type I isoform a [Homo
sapiens]
Length = 249
Score = 154 bits (388), Expect = 1e-37
Identities = 88/192 (45%), Positives = 116/192 (60%), Gaps = 5/192 (2%)
Query: 77 SDDNRLCTLASLKAVWHGQKLDFFK---QAHEGGPAPNSEVVLPDGFQSQHILDYAQGNR 133
S DN + T S + W K+ + + GG APN VV G Q +I ++ QGNR
Sbjct: 57 SHDNWIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSG-QRCNIWEFMQGNR 115
Query: 134 PLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYIIPQH 193
PLVLNFGSCT P FM + F+RL+ + DFL+IYIEEAH SDGW ++ I H
Sbjct: 116 PLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNN-MDIRNH 174
Query: 194 RSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDG 253
++L+DR+ AA +L +P C +V+DTM N SS Y A ERLY+IQ G I+Y+G GP
Sbjct: 175 QNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWN 234
Query: 254 YQVSELRTWLER 265
Y E+R LE+
Sbjct: 235 YNPEEVRAVLEK 246
>gi|7549803 deiodinase, iodothyronine, type II isoform a [Homo
sapiens]
Length = 273
Score = 152 bits (384), Expect = 3e-37
Identities = 86/208 (41%), Positives = 124/208 (59%), Gaps = 23/208 (11%)
Query: 81 RLCTLASLKAVWHGQKLDFFKQAHEGGPAPNSEVV----------LPDGFQSQ------- 123
R+ T L+ VW LD +KQ G APNS VV +G Q +
Sbjct: 53 RMLTSEGLRCVWKSFLLDAYKQVKLGEDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATC 112
Query: 124 HILDYAQGNRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDGW-V 182
H+LD+A RPLV+NFGS T PPF +++ AF++LV ++ DFL++YI+EAHPSDGW +
Sbjct: 113 HLLDFASPERPLVVNFGSATUPPFTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAI 172
Query: 183 TTDS--PYIIPQHRSLEDRVSAARVLQQG---APGCALVLDTMANSSSSAYGAYFERLYV 237
DS + + +H++ EDR +AA+ L + P C +V D M N+++ AYG FER+ +
Sbjct: 173 PGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAFERVCI 232
Query: 238 IQSGTIMYQGGRGPDGYQVSELRTWLER 265
+Q I Y GG+GP Y + E+R WLE+
Sbjct: 233 VQRQKIAYLGGKGPFSYNLQEVRHWLEK 260
>gi|7549805 deiodinase, iodothyronine, type II isoform a [Homo
sapiens]
Length = 273
Score = 152 bits (384), Expect = 3e-37
Identities = 86/208 (41%), Positives = 124/208 (59%), Gaps = 23/208 (11%)
Query: 81 RLCTLASLKAVWHGQKLDFFKQAHEGGPAPNSEVV----------LPDGFQSQ------- 123
R+ T L+ VW LD +KQ G APNS VV +G Q +
Sbjct: 53 RMLTSEGLRCVWKSFLLDAYKQVKLGEDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATC 112
Query: 124 HILDYAQGNRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDGW-V 182
H+LD+A RPLV+NFGS T PPF +++ AF++LV ++ DFL++YI+EAHPSDGW +
Sbjct: 113 HLLDFASPERPLVVNFGSATUPPFTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAI 172
Query: 183 TTDS--PYIIPQHRSLEDRVSAARVLQQG---APGCALVLDTMANSSSSAYGAYFERLYV 237
DS + + +H++ EDR +AA+ L + P C +V D M N+++ AYG FER+ +
Sbjct: 173 PGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAFERVCI 232
Query: 238 IQSGTIMYQGGRGPDGYQVSELRTWLER 265
+Q I Y GG+GP Y + E+R WLE+
Sbjct: 233 VQRQKIAYLGGKGPFSYNLQEVRHWLEK 260
>gi|55749998 deiodinase, iodothyronine, type II isoform b [Homo
sapiens]
Length = 309
Score = 139 bits (350), Expect = 3e-33
Identities = 100/290 (34%), Positives = 144/290 (49%), Gaps = 49/290 (16%)
Query: 20 LVLFPRFLGTAFMLWLLDFLCIRKH---FLGRRRRGQPEPEVELNSEGEEV--------- 67
L + P F L L D + + KH L R + + E L SEG
Sbjct: 12 LQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGLRCVWKSFLLDA 71
Query: 68 --PPDDPPICVSDDNRLCTLASLKAVWHGQKLDFFKQAHE-------GGPAPNSEVV--- 115
+ PP S D + L V+ K +H G APNS VV
Sbjct: 72 YKQLNCPPSGFSKDGHILUL-----VYEAYKSRLLVYSHLDLWMVKLGEDAPNSSVVHVS 126
Query: 116 -------LPDGFQSQ-------HILDYAQGNRPLVLNFGSCTUPPFMARMSAFQRLVTKY 161
+G Q + H+LD+A RPLV+NFGS T PPF +++ AF++LV ++
Sbjct: 127 STEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTSQLPAFRKLVEEF 186
Query: 162 QRDVDFLIIYIEEAHPSDGW-VTTDS--PYIIPQHRSLEDRVSAARVLQQG---APGCAL 215
DFL++YI+EAHPSDGW + DS + + +H++ EDR +AA+ L + P C +
Sbjct: 187 SSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRV 246
Query: 216 VLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDGYQVSELRTWLER 265
V D M N+++ AYG FER+ ++Q I Y GG+GP Y + E+R WLE+
Sbjct: 247 VADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEK 296
>gi|47132603 deiodinase, iodothyronine, type I isoform b [Homo
sapiens]
Length = 185
Score = 138 bits (348), Expect = 5e-33
Identities = 70/135 (51%), Positives = 90/135 (66%), Gaps = 1/135 (0%)
Query: 131 GNRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYII 190
GNRPLVLNFGSCT P FM + F+RL+ + DFL+IYIEEAH SDGW ++ I
Sbjct: 49 GNRPLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNN-MDI 107
Query: 191 PQHRSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRG 250
H++L+DR+ AA +L +P C +V+DTM N SS Y A ERLY+IQ G I+Y+G G
Sbjct: 108 RNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSG 167
Query: 251 PDGYQVSELRTWLER 265
P Y E+R LE+
Sbjct: 168 PWNYNPEEVRAVLEK 182
>gi|89357938 deiodinase, iodothyronine, type I isoform d [Homo
sapiens]
Length = 161
Score = 82.4 bits (202), Expect = 4e-16
Identities = 49/105 (46%), Positives = 62/105 (59%), Gaps = 4/105 (3%)
Query: 77 SDDNRLCTLASLKAVWHGQKLDFFK---QAHEGGPAPNSEVVLPDGFQSQHILDYAQGNR 133
S DN + T S + W K+ + + GG APN VV G Q +I ++ QGNR
Sbjct: 57 SHDNWIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSG-QRCNIWEFMQGNR 115
Query: 134 PLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPS 178
PLVLNFGSCT P FM + F+RL+ + DFL+IYIEEAH S
Sbjct: 116 PLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS 160
>gi|89357935 deiodinase, iodothyronine, type I isoform c [Homo
sapiens]
Length = 201
Score = 76.3 bits (186), Expect = 3e-14
Identities = 39/87 (44%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 179 DGWVTTDSPYIIPQHRSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVI 238
DGW ++ I H++L+DR+ AA +L +P C +V+DTM N SS Y A ERLY+I
Sbjct: 113 DGWAFKNN-MDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYII 171
Query: 239 QSGTIMYQGGRGPDGYQVSELRTWLER 265
Q G I+Y+G GP Y E+R LE+
Sbjct: 172 QEGRILYKGKSGPWNYNPEEVRAVLEK 198
>gi|117190519 sialidase 3 [Homo sapiens]
Length = 461
Score = 30.4 bits (67), Expect = 1.8
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 9/78 (11%)
Query: 154 FQRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYIIPQHRSLEDRVSAARVLQQGAPGC 213
FQRL Q E H G V + P IP HR + A +QQ +PG
Sbjct: 296 FQRLALSRQ--------LCEPPHGCQGSVVSFRPLEIP-HRCQDSSSKDAPTIQQSSPGS 346
Query: 214 ALVLDTMANSSSSAYGAY 231
+L L+ A + S ++ Y
Sbjct: 347 SLRLEEEAGTPSESWLLY 364
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 28.9 bits (63), Expect = 5.2
Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Query: 52 GQPEPEVELNSEGEEVPPDDPPICVSDDNRLCTLASLKAVWHGQK 96
G+ EP EL EE PD PP+ V+ + T S++ W K
Sbjct: 1029 GRSEPSKELTISTEEAAPDGPPMDVT--LQPVTSQSIQVTWKAPK 1071
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,141,104
Number of Sequences: 37866
Number of extensions: 573781
Number of successful extensions: 1438
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1422
Number of HSP's gapped (non-prelim): 10
length of query: 278
length of database: 18,247,518
effective HSP length: 101
effective length of query: 177
effective length of database: 14,423,052
effective search space: 2552880204
effective search space used: 2552880204
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.