Guide to the Human Genome
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Search of human proteins with 55749667

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55749667 WSC domain containing 2 [Homo sapiens]
         (565 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55749667 WSC domain containing 2 [Homo sapiens]                   1180   0.0  
gi|54792094 WSC domain containing 1 [Homo sapiens]                    568   e-162
gi|13375642 kringle-containing transmembrane protein 2 isoform b...    61   2e-09
gi|27437008 kringle-containing transmembrane protein 2 isoform d...    61   2e-09
gi|24041012 kringle-containing transmembrane protein 1 isoform 2...    52   2e-06
gi|227116325 kringle-containing transmembrane protein 1 isoform ...    52   2e-06
gi|74024919 sulfotransferase family, cytosolic, 6B, member 1 [Ho...    33   0.70 
gi|4885617 sulfotransferase, estrogen-preferring [Homo sapiens]        32   1.2  
gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens]            32   1.2  
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    30   4.5  
gi|29540545 bile-salt sulfotransferase 2A1 [Homo sapiens]              30   5.9  
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]               30   7.7  
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]       30   7.7  

>gi|55749667 WSC domain containing 2 [Homo sapiens]
          Length = 565

 Score = 1180 bits (3053), Expect = 0.0
 Identities = 565/565 (100%), Positives = 565/565 (100%)

Query: 1   MAKLWFKFQRYFRRKPVRFFTFLALYLTAGSLVFLHSGFVGQPAVSGNQANPAAAGGPAE 60
           MAKLWFKFQRYFRRKPVRFFTFLALYLTAGSLVFLHSGFVGQPAVSGNQANPAAAGGPAE
Sbjct: 1   MAKLWFKFQRYFRRKPVRFFTFLALYLTAGSLVFLHSGFVGQPAVSGNQANPAAAGGPAE 60

Query: 61  GAELSFLGDMHLGRGFRDTGEASSIARRYGPWFKGKDGNERAKLGDYGGAWSRALKGRVV 120
           GAELSFLGDMHLGRGFRDTGEASSIARRYGPWFKGKDGNERAKLGDYGGAWSRALKGRVV
Sbjct: 61  GAELSFLGDMHLGRGFRDTGEASSIARRYGPWFKGKDGNERAKLGDYGGAWSRALKGRVV 120

Query: 121 REKEEERAKYIGCYLDDTQSRALRGVSFFDYKKMTIFRCQDNCAERGYLYGGLEFGAECY 180
           REKEEERAKYIGCYLDDTQSRALRGVSFFDYKKMTIFRCQDNCAERGYLYGGLEFGAECY
Sbjct: 121 REKEEERAKYIGCYLDDTQSRALRGVSFFDYKKMTIFRCQDNCAERGYLYGGLEFGAECY 180

Query: 181 CGHKIQATNVSEAECDMECKGERGSVCGGANRLSVYRLQLAQESARRYGSAVFRGCFRRP 240
           CGHKIQATNVSEAECDMECKGERGSVCGGANRLSVYRLQLAQESARRYGSAVFRGCFRRP
Sbjct: 181 CGHKIQATNVSEAECDMECKGERGSVCGGANRLSVYRLQLAQESARRYGSAVFRGCFRRP 240

Query: 241 DNLSLALPVTAAMLNMSVDKCVDFCTEKEYPLAALAGTACHCGFPTTRFPLHDREDEQLC 300
           DNLSLALPVTAAMLNMSVDKCVDFCTEKEYPLAALAGTACHCGFPTTRFPLHDREDEQLC
Sbjct: 241 DNLSLALPVTAAMLNMSVDKCVDFCTEKEYPLAALAGTACHCGFPTTRFPLHDREDEQLC 300

Query: 301 AQKCSAEEFESCGTPSYFIVYQTQVQDNRCMDRRFLPGKSKQLIALASFPGAGNTWARHL 360
           AQKCSAEEFESCGTPSYFIVYQTQVQDNRCMDRRFLPGKSKQLIALASFPGAGNTWARHL
Sbjct: 301 AQKCSAEEFESCGTPSYFIVYQTQVQDNRCMDRRFLPGKSKQLIALASFPGAGNTWARHL 360

Query: 361 IELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDAAILLIRN 420
           IELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDAAILLIRN
Sbjct: 361 IELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDAAILLIRN 420

Query: 421 PYKALMAEFNRKYGGHIGFAAHAHWKGKEWPEFVRNYAPWWATHTLDWLKFGKKVLVVHF 480
           PYKALMAEFNRKYGGHIGFAAHAHWKGKEWPEFVRNYAPWWATHTLDWLKFGKKVLVVHF
Sbjct: 421 PYKALMAEFNRKYGGHIGFAAHAHWKGKEWPEFVRNYAPWWATHTLDWLKFGKKVLVVHF 480

Query: 481 EDLKQDLFVQLGRMVSLLGVAVREDRLLCVESQKDGNFKRSGLRKLEYDPYTADMQKTIS 540
           EDLKQDLFVQLGRMVSLLGVAVREDRLLCVESQKDGNFKRSGLRKLEYDPYTADMQKTIS
Sbjct: 481 EDLKQDLFVQLGRMVSLLGVAVREDRLLCVESQKDGNFKRSGLRKLEYDPYTADMQKTIS 540

Query: 541 AYIKMVDAALKGRNLTGVPDDYYPR 565
           AYIKMVDAALKGRNLTGVPDDYYPR
Sbjct: 541 AYIKMVDAALKGRNLTGVPDDYYPR 565


>gi|54792094 WSC domain containing 1 [Homo sapiens]
          Length = 575

 Score =  568 bits (1463), Expect = e-162
 Identities = 288/582 (49%), Positives = 374/582 (64%), Gaps = 24/582 (4%)

Query: 1   MAKLWFKFQRYFRRKPVRFFTFLALYLTAGSLVFLHSGFVGQP----AVSGNQANPAAAG 56
           MAK +F+ Q++ RR     F   A YL  GSL+ L    V  P    A    Q  P AA 
Sbjct: 1   MAKPFFRLQKFLRRTQFLLFFLTAAYLMTGSLLLLQRVRVALPQGPRAPGPLQTLPVAAV 60

Query: 57  GPAEGA-ELSFLGDMHLGRGFR---DTGEASSIARRYGP-WFKGKDGNERAK-------- 103
               G  +   L D  +        D  ++     R GP W + ++   R          
Sbjct: 61  ALGVGLLDSRALHDPRVSPELLLGVDMLQSPLTRPRPGPRWLRSRNSELRQLRRRWFHHF 120

Query: 104 LGDYGGAWSRALKGRVVREKEEERAKYIGCYLDDTQSRALRGVSFFDYKKMTIFRCQDNC 163
           + D  G    AL     R     R  YIGC+ DD   R L+G  F+D +KMT+  CQD C
Sbjct: 121 MSDSQGP--PALGPEAARPAIHSRGTYIGCFSDDGHERTLKGAVFYDLRKMTVSHCQDAC 178

Query: 164 AERGYLYGGLEFGAECYCGHKIQATNVSEAECDMECKGERGSVCGGANRLSVYRLQLAQE 223
           AER Y+Y GLE GAECYCG+++ A +V   EC+ ECKGE+GSVCG  +RLSVYR+   Q 
Sbjct: 179 AERSYVYAGLEAGAECYCGNRLPAVSVGLEECNHECKGEKGSVCGAVDRLSVYRVDELQP 238

Query: 224 SARRYGSAVFRGCFRRPDNLSLALPVTAAMLNMSVDKCVDFCTEKEYPLAALAGTACHCG 283
            +R+  +A +RGCFR P+N++ A P +    N++V  C  FC++KE+PLA L G  C+C 
Sbjct: 239 GSRKRRTATYRGCFRLPENITHAFPSSLIQANVTVGTCSGFCSQKEFPLAILRGWECYCA 298

Query: 284 FPTTRFPLHDREDEQLCAQKCSAEEFESCGTPSYFIVYQTQVQDNRCMDRRFLPGKSKQL 343
           +PT RF L D  D  +C Q   A+         Y  VYQT VQD RC DRRFLP KSK  
Sbjct: 299 YPTPRFNLRDAMDSSVCGQDPEAQRLAE-----YCEVYQTPVQDTRCTDRRFLPNKSKVF 353

Query: 344 IALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHES 403
           +AL+SFPGAGNTWARHLIE ATGFYTGSYYFDG+LYNKGFKGE+DHWRS RTIC+KTHES
Sbjct: 354 VALSSFPGAGNTWARHLIEHATGFYTGSYYFDGTLYNKGFKGEKDHWRSRRTICVKTHES 413

Query: 404 GQKEIEAFDAAILLIRNPYKALMAEFNRKYGGHIGFAAHAHWKGKEWPEFVRNYAPWWAT 463
           G++EIE FD+AILLIRNPY++L+AEFNRK  GH+G+AA  +WK KEWP+FV +YA WW++
Sbjct: 414 GRREIEMFDSAILLIRNPYRSLVAEFNRKCAGHLGYAADRNWKSKEWPDFVNSYASWWSS 473

Query: 464 HTLDWLKFGKKVLVVHFEDLKQDLFVQLGRMVSLLGVAVREDRLLCVESQKDGNFKRSGL 523
           H LDWLK+GK++LVVH+E+L++ L   L  MV+ L V+V E+RLLCVE+ K+G+F+R G 
Sbjct: 474 HVLDWLKYGKRLLVVHYEELRRSLVPTLREMVAFLNVSVSEERLLCVENNKEGSFRRRGR 533

Query: 524 RKLEYDPYTADMQKTISAYIKMVDAALKGRNLTGVPDDYYPR 565
           R  + +P+T +M+  I+ YI+ VD AL+  N TG+P +Y PR
Sbjct: 534 RSHDPEPFTPEMKDLINGYIRTVDQALRDHNWTGLPREYVPR 575


>gi|13375642 kringle-containing transmembrane protein 2 isoform b
           precursor [Homo sapiens]
          Length = 420

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 4/94 (4%)

Query: 130 YIGCYLDDTQSRALRGVSFFDYKKMTIFRCQDNCAERGYLYGGLEFGAECYCGHKIQATN 189
           Y+GC++D     AL G S     K+T+  C   C  +GY   G+E G  C+CG +     
Sbjct: 124 YLGCFVDSGAPPALSGPSGTS-TKLTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLAR 182

Query: 190 ---VSEAECDMECKGERGSVCGGANRLSVYRLQL 220
                  +CD  C G  G +CGG  RL VY + +
Sbjct: 183 GRLAPATDCDQICFGHPGQLCGGDGRLGVYEVSV 216


>gi|27437008 kringle-containing transmembrane protein 2 isoform d
           precursor [Homo sapiens]
          Length = 462

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 4/94 (4%)

Query: 130 YIGCYLDDTQSRALRGVSFFDYKKMTIFRCQDNCAERGYLYGGLEFGAECYCGHKIQATN 189
           Y+GC++D     AL G S     K+T+  C   C  +GY   G+E G  C+CG +     
Sbjct: 124 YLGCFVDSGAPPALSGPSGTS-TKLTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLAR 182

Query: 190 ---VSEAECDMECKGERGSVCGGANRLSVYRLQL 220
                  +CD  C G  G +CGG  RL VY + +
Sbjct: 183 GRLAPATDCDQICFGHPGQLCGGDGRLGVYEVSV 216


>gi|24041012 kringle-containing transmembrane protein 1 isoform 2
           precursor [Homo sapiens]
          Length = 492

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 4/89 (4%)

Query: 131 IGCYLDDTQSRALRGVSFFDYKKMTIFRCQDNCAERGYLYGGLEFGAECYCGHKIQATNV 190
           +GCY D      L G S     K+TI  C   C  + + + G+E G  C+CG+       
Sbjct: 122 LGCYKDHGNPPPLTGTSKTS-NKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKY 180

Query: 191 SEA---ECDMECKGERGSVCGGANRLSVY 216
            EA   EC+  C G+    CGG  R+ ++
Sbjct: 181 GEAASTECNSVCFGDHTQPCGGDGRIILF 209



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 19/92 (20%), Positives = 37/92 (40%), Gaps = 2/92 (2%)

Query: 235 GCFRRPDNLSLALPVTAAMLNMSVDKCVDFCTEKEYPLAAL-AGTACHCGFPTTRFPLHD 293
           GC++   N       +     +++  C+ FC  + +  A + +G AC CG     +   +
Sbjct: 123 GCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKYGE 182

Query: 294 REDEQLCAQKCSAEEFESCGTPSYFIVYQTQV 325
               + C   C  +  + CG     I++ T V
Sbjct: 183 AASTE-CNSVCFGDHTQPCGGDGRIILFDTLV 213


>gi|227116325 kringle-containing transmembrane protein 1 isoform 3
           precursor [Homo sapiens]
          Length = 458

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 4/89 (4%)

Query: 131 IGCYLDDTQSRALRGVSFFDYKKMTIFRCQDNCAERGYLYGGLEFGAECYCGHKIQATNV 190
           +GCY D      L G S     K+TI  C   C  + + + G+E G  C+CG+       
Sbjct: 122 LGCYKDHGNPPPLTGTSKTS-NKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKY 180

Query: 191 SEA---ECDMECKGERGSVCGGANRLSVY 216
            EA   EC+  C G+    CGG  R+ ++
Sbjct: 181 GEAASTECNSVCFGDHTQPCGGDGRIILF 209



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 19/92 (20%), Positives = 37/92 (40%), Gaps = 2/92 (2%)

Query: 235 GCFRRPDNLSLALPVTAAMLNMSVDKCVDFCTEKEYPLAAL-AGTACHCGFPTTRFPLHD 293
           GC++   N       +     +++  C+ FC  + +  A + +G AC CG     +   +
Sbjct: 123 GCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKYGE 182

Query: 294 REDEQLCAQKCSAEEFESCGTPSYFIVYQTQV 325
               + C   C  +  + CG     I++ T V
Sbjct: 183 AASTE-CNSVCFGDHTQPCGGDGRIILFDTLV 213


>gi|74024919 sulfotransferase family, cytosolic, 6B, member 1 [Homo
           sapiens]
          Length = 265

 Score = 33.1 bits (74), Expect = 0.70
 Identities = 45/190 (23%), Positives = 75/190 (39%), Gaps = 31/190 (16%)

Query: 344 IALASFPGAGNTWARHLI-ELATGFYTGSYYF---------DGSLYN--KGFKGERDHWR 391
           I LAS+P  G+ W  H++ EL        Y +         D   Y   KGF   R    
Sbjct: 20  IVLASYPKCGSNWILHIVSELIYAVSKKKYKYPEFPVLECGDSEKYQRMKGFPSPR---- 75

Query: 392 SGRTICIKTHESGQK---EIEAFDAAILLI-RNPYKALMAEFNRKYGGHIGFAAHAHWKG 447
                 + TH    K    I    A IL+I RNP K     F   +       ++  W  
Sbjct: 76  -----ILATHLHYDKLPGSIFENKAKILVIFRNP-KDTAVSFLHFHNDVPDIPSYGSW-D 128

Query: 448 KEWPEFVRNYAPW--WATHTLDWLKF--GKKVLVVHFEDLKQDLFVQLGRMVSLLGVAVR 503
           + + +F++    W  +    ++W K   G  V  + +EDLK++L   + ++   LG  + 
Sbjct: 129 EFFRQFMKGQVSWGRYFDFAINWNKHLDGDNVKFILYEDLKENLAAGIKQIAEFLGFFLT 188

Query: 504 EDRLLCVESQ 513
            +++  +  Q
Sbjct: 189 GEQIQTISVQ 198


>gi|4885617 sulfotransferase, estrogen-preferring [Homo sapiens]
          Length = 294

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 8/57 (14%)

Query: 450 WPEFVRNY----APW--WATHTLDWLKFGK--KVLVVHFEDLKQDLFVQLGRMVSLL 498
           +PEFV  +     P+  W  H   W + GK  +VL + +EDLK+D+  ++ +++  L
Sbjct: 154 FPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSPRVLFLFYEDLKEDIRKEVIKLIHFL 210


>gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens]
          Length = 511

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 10/83 (12%)

Query: 398 IKTHESGQKEIEAFDAAILLIRNPYKALMAEFNRKY----GGHIGFAAHAHWKGKEWPEF 453
           ++T  S Q EI+ F      I +  K  + E  R++      H GFA H H+   +  E 
Sbjct: 164 VETVTSRQSEIQKF------IADGCKEALLEEKRRFCFLVDKHCGFANHIHYYHLQSAEL 217

Query: 454 VRNYAPWWATHTLDWLKFGKKVL 476
           + +  P W    +D +K  +K++
Sbjct: 218 LNSKLPRWQETCVDAIKVPEKIM 240


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 30.4 bits (67), Expect = 4.5
 Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 4/51 (7%)

Query: 16   PVRFFTFLALYLTAGSLVFLHSGFVGQPAVSGNQANP----AAAGGPAEGA 62
            P+     L+L    GSL+FL S   G     G+  +P    AAA GP EGA
Sbjct: 1613 PISLDGSLSLGAEPGSLLFLQSAAAGLGLALGDAGDPGPPDAAAPGPREGA 1663


>gi|29540545 bile-salt sulfotransferase 2A1 [Homo sapiens]
          Length = 285

 Score = 30.0 bits (66), Expect = 5.9
 Identities = 28/128 (21%), Positives = 52/128 (40%), Gaps = 20/128 (15%)

Query: 415 ILLIRNPYKALMAEFNRKYGGHIGFAAHAHWKGKEWPEFVRNYAPW------WATHTLDW 468
           I L+RNP   L++ +   +  ++ F      K K W E+   +         W  H   W
Sbjct: 117 IYLMRNPRDVLVSGYF--FWKNMKFIK----KPKSWEEYFEWFCQGTVLYGSWFDHIHGW 170

Query: 469 LKFG--KKVLVVHFEDLKQDLFVQLGRMVSLLGVAVREDRLLCV------ESQKDGNFKR 520
           +     K  L++ +E+LKQD    + ++   LG  +  + L  +      +S K+     
Sbjct: 171 MPMREEKNFLLLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSN 230

Query: 521 SGLRKLEY 528
             L  ++Y
Sbjct: 231 YSLLSVDY 238


>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
          Length = 2526

 Score = 29.6 bits (65), Expect = 7.7
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 10/83 (12%)

Query: 38   GFVGQPAVSGNQANPAAAGGPAEGAELSFLGDMHLGRGFRDTGEASSIARRYGPWFKGKD 97
            G  G+    G+Q +P + G P +  E  F GD        + G+ ++I  + G   KG+ 
Sbjct: 1482 GIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDP------GNPGQNNNIKGQKGS--KGEQ 1533

Query: 98   GNE--RAKLGDYGGAWSRALKGR 118
            G +    + G  G   SR  +GR
Sbjct: 1534 GRQGRSGQKGVQGSPSSRGSRGR 1556


>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
          Length = 4314

 Score = 29.6 bits (65), Expect = 7.7
 Identities = 28/111 (25%), Positives = 52/111 (46%), Gaps = 20/111 (18%)

Query: 444 HWKGKEWPEFVRNYAPW----WATHTLDWLKFGKKVLVVHFEDLKQDLFVQLGRMVSLLG 499
           H  G+ W  +V +  PW    +   TLD  K GK+        L++ L ++      L  
Sbjct: 300 HLTGQVWQRYVPH--PWKNEKYFPETLD--KLGKR--------LEEVLAIRTIHEKFLYF 347

Query: 500 VAVREDRLLCVESQKDGNFKRSGLRKLEYDPYTADMQK-TISAYIKMVDAA 549
           +   E++++C+    +     +GL  ++Y+PYT  + K  +S Y K++  A
Sbjct: 348 LPASEEKIICLTRVFE---PFTGLNPVQYNPYTEPLWKAAVSQYEKIIAPA 395


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,468,401
Number of Sequences: 37866
Number of extensions: 1057360
Number of successful extensions: 2312
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2288
Number of HSP's gapped (non-prelim): 19
length of query: 565
length of database: 18,247,518
effective HSP length: 108
effective length of query: 457
effective length of database: 14,157,990
effective search space: 6470201430
effective search space used: 6470201430
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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