Search of human proteins with 5453599

Search of human proteins with 5453599

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453599 capping protein (actin filament) muscle Z-line,
alpha 2 [Homo sapiens]
         (286 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453599 capping protein (actin filament) muscle Z-line, alpha...   585   e-167
gi|5453597 F-actin capping protein alpha-1 subunit [Homo sapiens]     520   e-148
gi|15277417 capping protein alpha 3 [Homo sapiens]                    195   4e-50
gi|105990532 apolipoprotein B precursor [Homo sapiens]                 30   1.9  
gi|45267824 heparan sulfate (glucosamine) 3-O-sulfotransferase 5...    30   1.9  
gi|18450278 dipeptidyl peptidase 8 isoform 2 [Homo sapiens]            28   7.1  
gi|37577089 dipeptidyl peptidase 8 isoform 3 [Homo sapiens]            28   7.1  
gi|37577091 dipeptidyl peptidase 8 isoform 4 [Homo sapiens]            28   7.1  
gi|18450280 dipeptidyl peptidase 8 isoform 1 [Homo sapiens]            28   7.1  
gi|145275198 ADAMTS-like 3 precursor [Homo sapiens]                    28   9.2  
gi|4503817 3-ketodihydrosphingosine reductase precursor [Homo sa...    28   9.2  
gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H...    28   9.2  

>gi|5453599 capping protein (actin filament) muscle Z-line, alpha 2
           [Homo sapiens]
          Length = 286

 Score =  585 bits (1507), Expect = e-167
 Identities = 286/286 (100%), Positives = 286/286 (100%)

Query: 1   MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLD 60
           MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLD
Sbjct: 1   MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLD 60

Query: 61  QFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESW 120
           QFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESW
Sbjct: 61  QFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESW 120

Query: 121 RTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFT 180
           RTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFT
Sbjct: 121 RTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFT 180

Query: 181 ITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQ 240
           ITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQ
Sbjct: 181 ITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQ 240

Query: 241 TAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA 286
           TAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
Sbjct: 241 TAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA 286


>gi|5453597 F-actin capping protein alpha-1 subunit [Homo sapiens]
          Length = 286

 Score =  520 bits (1339), Expect = e-148
 Identities = 248/286 (86%), Positives = 267/286 (93%)

Query: 1   MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLD 60
           MAD ++++SDEEKVRIAAKFI HAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYN+D
Sbjct: 1   MADFDDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMD 60

Query: 61  QFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESW 120
           QFTPVKIEGYEDQVLITEHGDLGN +FLDP+N+I FKFDHLRKEA+DP+P E +  ++SW
Sbjct: 61  QFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEADGGLKSW 120

Query: 121 RTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFT 180
           R S ++ALRAYVK+HY NG CTVY K IDGQQTIIACIESHQFQ KNFWNGRWRSEWKFT
Sbjct: 121 RESCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFT 180

Query: 181 ITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQ 240
           ITP T QVVG+LKIQVHYYEDGNVQLVSHKD+QDSLTVSNE QTAKEFIKI+E AENEYQ
Sbjct: 181 ITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSLTVSNEAQTAKEFIKIIENAENEYQ 240

Query: 241 TAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA 286
           TAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
Sbjct: 241 TAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA 286


>gi|15277417 capping protein alpha 3 [Homo sapiens]
          Length = 299

 Score =  195 bits (495), Expect = 4e-50
 Identities = 98/271 (36%), Positives = 162/271 (59%), Gaps = 4/271 (1%)

Query: 8   LSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKI 67
           LS ++K R+  + ++ APPGEF   F+D+ LL+ ++ L+      A  Q+      P+ I
Sbjct: 6   LSRKDKERVIRRLLLQAPPGEFVNAFDDLCLLIRDEKLMHHQGECAGHQHCQKYSVPLCI 65

Query: 68  EGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEV-ENAVESWRTSVET 126
           +G  + VL++ H  +G+ +F D ++++ FK+D L+ +  D +   + +N  E  R  +  
Sbjct: 66  DG--NPVLLSHHNVMGDYRFFDHQSKLSFKYDLLQNQLKDIQSHGIIQNEAEYLRVVLLC 123

Query: 127 ALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTT 186
           AL+ YV +HYP G C +  K +  ++ +IACIE H ++    WNG W+S+W F + P  T
Sbjct: 124 ALKLYVNDHYPKGNCNMLRKTVKSKEYLIACIEDHNYETGECWNGLWKSKWIFQVNPFLT 183

Query: 187 QVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISEN 246
           QV G + +Q H++   N+ +   KD+++SL + N+ Q A  F ++VE  EN++Q A+ E 
Sbjct: 184 QVTGRIFVQAHFFRCVNLHIEISKDLKESLEIVNQAQLALSFARLVEEQENKFQAAVLEE 243

Query: 247 YQTMSDTTF-KALRRQLPVTRTKIDWNKILS 276
            Q +S+    K LRR LPVTRT IDW++ILS
Sbjct: 244 LQELSNEALRKILRRDLPVTRTLIDWHRILS 274


>gi|105990532 apolipoprotein B precursor [Homo sapiens]
          Length = 4563

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 46/194 (23%), Positives = 73/194 (37%), Gaps = 42/194 (21%)

Query: 86   KFLDPKNRICFKFDHLRKEATDP--RPCEVENAVESW--RTSVETALRAYVKEHYPNGVC 141
            KFLD       KF H+ K   +P  +   + +A  SW  + S    L +  K+H      
Sbjct: 1429 KFLDSN----IKFSHVEKLGNNPVSKGLLIFDASSSWGPQMSASVHLDSKKKQHL----- 1479

Query: 142  TVYGKKIDGQQTIIACIESHQFQAKNFW-------------NGRWRSEWKFTITPSTTQV 188
             V   KIDGQ  + +      F AK  +             NG     +  +    T Q+
Sbjct: 1480 FVKEVKIDGQFRVSS------FYAKGTYGLSCQRDPNTGRLNGESNLRFNSSYLQGTNQI 1533

Query: 189  VGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAE--NEYQTAISEN 246
             G        YEDG + L S  D+Q  + + N      E  ++   ++   +Y+   + N
Sbjct: 1534 TG-------RYEDGTLSLTSTSDLQSGI-IKNTASLKYENYELTLKSDTNGKYKNFATSN 1585

Query: 247  YQTMSDTTFKALRR 260
               M+ +   AL R
Sbjct: 1586 KMDMTFSKQNALLR 1599


>gi|45267824 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
           [Homo sapiens]
          Length = 346

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 5/51 (9%)

Query: 76  ITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESWRTSVET 126
           I+++  +  GK  + KN+  +KF+ L   A DP  CEV    ++ RTS+ T
Sbjct: 190 ISDYTQVLEGK--ERKNKTYYKFEKL---AIDPNTCEVNTKYKAVRTSIYT 235


>gi|18450278 dipeptidyl peptidase 8 isoform 2 [Homo sapiens]
          Length = 782

 Score = 28.5 bits (62), Expect = 7.1
 Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 58  NLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAV 117
           N  + T +   GY     I++H D    K+ + KN  C     L     DP  C+ +   
Sbjct: 543 NPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDP-TCKTK--- 598

Query: 118 ESWRTSVETA 127
           E W T +++A
Sbjct: 599 EFWATILDSA 608


>gi|37577089 dipeptidyl peptidase 8 isoform 3 [Homo sapiens]
          Length = 898

 Score = 28.5 bits (62), Expect = 7.1
 Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 58  NLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAV 117
           N  + T +   GY     I++H D    K+ + KN  C     L     DP  C+ +   
Sbjct: 559 NPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDP-TCKTK--- 614

Query: 118 ESWRTSVETA 127
           E W T +++A
Sbjct: 615 EFWATILDSA 624


>gi|37577091 dipeptidyl peptidase 8 isoform 4 [Homo sapiens]
          Length = 847

 Score = 28.5 bits (62), Expect = 7.1
 Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 58  NLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAV 117
           N  + T +   GY     I++H D    K+ + KN  C     L     DP  C+ +   
Sbjct: 559 NPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDP-TCKTK--- 614

Query: 118 ESWRTSVETA 127
           E W T +++A
Sbjct: 615 EFWATILDSA 624


>gi|18450280 dipeptidyl peptidase 8 isoform 1 [Homo sapiens]
          Length = 882

 Score = 28.5 bits (62), Expect = 7.1
 Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 58  NLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAV 117
           N  + T +   GY     I++H D    K+ + KN  C     L     DP  C+ +   
Sbjct: 543 NPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDP-TCKTK--- 598

Query: 118 ESWRTSVETA 127
           E W T +++A
Sbjct: 599 EFWATILDSA 608


>gi|145275198 ADAMTS-like 3 precursor [Homo sapiens]
          Length = 1691

 Score = 28.1 bits (61), Expect = 9.2
 Identities = 15/58 (25%), Positives = 24/58 (41%)

Query: 99   DHLRKEATDPRPCEVENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIA 156
            DHL+K      PC + +    W TSV +       E Y +   T    K +G   +++
Sbjct: 1466 DHLQKPLAGFEPCNIRDCPARWFTSVWSQCSVSCGEGYHSRQVTCKRTKANGTVQVVS 1523


>gi|4503817 3-ketodihydrosphingosine reductase precursor [Homo
           sapiens]
          Length = 332

 Score = 28.1 bits (61), Expect = 9.2
 Identities = 19/67 (28%), Positives = 34/67 (50%), Gaps = 1/67 (1%)

Query: 193 KIQVHYYEDGNVQLVSHKDI-QDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMS 251
           +I++H   D  V L    D+ QD   V N ++ A+E +  V+   N    A+S  ++ + 
Sbjct: 75  EIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLE 134

Query: 252 DTTFKAL 258
            +TF+ L
Sbjct: 135 VSTFERL 141


>gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo
            sapiens]
          Length = 1453

 Score = 28.1 bits (61), Expect = 9.2
 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 3/77 (3%)

Query: 168  FWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKE 227
            F+NG W S  +  IT   T + GI+  Q+   E+G V L             +++Q  K 
Sbjct: 1159 FYNGTWGSVGRRNIT---TAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKT 1215

Query: 228  FIKIVEAAENEYQTAIS 244
             I I +     ++  IS
Sbjct: 1216 HISIWQCLSAPWERRIS 1232


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,490,015
Number of Sequences: 37866
Number of extensions: 436926
Number of successful extensions: 991
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 984
Number of HSP's gapped (non-prelim): 12
length of query: 286
length of database: 18,247,518
effective HSP length: 101
effective length of query: 185
effective length of database: 14,423,052
effective search space: 2668264620
effective search space used: 2668264620
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.