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Search of human proteins with 53832021
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|53832021 carboxypeptidase M precursor [Homo sapiens]
(443 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|53832021 carboxypeptidase M precursor [Homo sapiens] 927 0.0
gi|38327526 carboxypeptidase M precursor [Homo sapiens] 927 0.0
gi|6631081 carboxypeptidase M precursor [Homo sapiens] 927 0.0
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 368 e-102
gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sap... 307 1e-83
gi|4503009 carboxypeptidase E preproprotein [Homo sapiens] 300 2e-81
gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens] 266 2e-71
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 266 2e-71
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 266 2e-71
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 251 7e-67
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens] 249 4e-66
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 216 3e-56
gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens] 54 2e-07
gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens] 48 2e-05
gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo s... 46 8e-05
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens] 45 1e-04
gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens] 44 2e-04
gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens] 44 2e-04
gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens] 44 2e-04
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa... 44 4e-04
gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein ... 37 0.036
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens] 35 0.14
gi|27436871 carboxypeptidase O [Homo sapiens] 34 0.30
gi|157388919 homolog of yeast tRNA methyltransferase 12 [Homo sa... 31 2.6
gi|4502997 carboxypeptidase A1 precursor [Homo sapiens] 30 3.4
gi|194097335 lipase C precursor [Homo sapiens] 30 5.7
gi|239787844 testis expressed 10 isoform 2 [Homo sapiens] 30 5.7
gi|239787838 testis expressed 10 isoform 1 [Homo sapiens] 30 5.7
gi|157266292 intestinal alkaline phosphatase precursor [Homo sap... 29 9.8
gi|20270323 zinc finger protein 653 [Homo sapiens] 29 9.8
>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 927 bits (2395), Expect = 0.0
Identities = 443/443 (100%), Positives = 443/443 (100%)
Query: 1 MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL 60
MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL
Sbjct: 1 MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL 60
Query: 61 VVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIH 120
VVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIH
Sbjct: 61 VVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIH 120
Query: 121 IMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKT 180
IMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKT
Sbjct: 121 IMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKT 180
Query: 181 ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240
ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD
Sbjct: 181 ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240
Query: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNN 300
ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNN
Sbjct: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNN 300
Query: 301 KASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSY 360
KASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSY
Sbjct: 301 KASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSY 360
Query: 361 IINVTVPGHDPHITKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLP 420
IINVTVPGHDPHITKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLP
Sbjct: 361 IINVTVPGHDPHITKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLP 420
Query: 421 DHSAATKPSLFLFLVSLLHIFFK 443
DHSAATKPSLFLFLVSLLHIFFK
Sbjct: 421 DHSAATKPSLFLFLVSLLHIFFK 443
>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 927 bits (2395), Expect = 0.0
Identities = 443/443 (100%), Positives = 443/443 (100%)
Query: 1 MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL 60
MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL
Sbjct: 1 MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL 60
Query: 61 VVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIH 120
VVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIH
Sbjct: 61 VVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIH 120
Query: 121 IMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKT 180
IMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKT
Sbjct: 121 IMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKT 180
Query: 181 ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240
ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD
Sbjct: 181 ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240
Query: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNN 300
ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNN
Sbjct: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNN 300
Query: 301 KASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSY 360
KASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSY
Sbjct: 301 KASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSY 360
Query: 361 IINVTVPGHDPHITKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLP 420
IINVTVPGHDPHITKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLP
Sbjct: 361 IINVTVPGHDPHITKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLP 420
Query: 421 DHSAATKPSLFLFLVSLLHIFFK 443
DHSAATKPSLFLFLVSLLHIFFK
Sbjct: 421 DHSAATKPSLFLFLVSLLHIFFK 443
>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 927 bits (2395), Expect = 0.0
Identities = 443/443 (100%), Positives = 443/443 (100%)
Query: 1 MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL 60
MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL
Sbjct: 1 MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL 60
Query: 61 VVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIH 120
VVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIH
Sbjct: 61 VVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIH 120
Query: 121 IMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKT 180
IMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKT
Sbjct: 121 IMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKT 180
Query: 181 ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240
ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD
Sbjct: 181 ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240
Query: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNN 300
ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNN
Sbjct: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNN 300
Query: 301 KASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSY 360
KASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSY
Sbjct: 301 KASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSY 360
Query: 361 IINVTVPGHDPHITKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLP 420
IINVTVPGHDPHITKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLP
Sbjct: 361 IINVTVPGHDPHITKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLP 420
Query: 421 DHSAATKPSLFLFLVSLLHIFFK 443
DHSAATKPSLFLFLVSLLHIFFK
Sbjct: 421 DHSAATKPSLFLFLVSLLHIFFK 443
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 368 bits (945), Expect = e-102
Identities = 184/361 (50%), Positives = 248/361 (68%), Gaps = 10/361 (2%)
Query: 19 DFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKY 78
DF++H ME FL+ A Y ++T L+S+GKSV+ R L+V+ + P H G PEFKY
Sbjct: 500 DFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKY 559
Query: 79 VANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138
+ NMHG+E VGRELLL+LI+YL + G DPE+T+L+++TRIH+MPSMNPDG+E ++ D
Sbjct: 560 IGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDS 619
Query: 139 YYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVASY 198
IGR N N +DLNRNFPD F QPET+AVM W+K+ FVLSANLHGG+LV +Y
Sbjct: 620 ISVIGRNNSNNFDLNRNFPDQFVQITDPTQPETIAVMSWMKSYPFVLSANLHGGSLVVNY 679
Query: 199 PFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMN---FPNGVTNG 255
PFD+ Q A YS+S PDD VFQ +A +Y+ N M +G CKN FP+G+TNG
Sbjct: 680 PFDDDEQGL-ATYSKS--PDDAVFQQIALSYSKENSQMFQGRPCKNMYPNEYFPHGITNG 736
Query: 256 YSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGV 315
SWY + GGMQD+NY+ CFE+T+EL C KYP E++LP+FW N+ SLI+++KQVH GV
Sbjct: 737 ASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQNRRSLIQFMKQVHQGV 796
Query: 316 KGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHIT 374
+G V D +G + N + V + H P T K G+Y+ LL+PG+Y I + G++P +T
Sbjct: 797 RGFVLDATDGRGILNATISVAEINH--PVTTYKTGDYWRLLVPGTYKITASARGYNP-VT 853
Query: 375 K 375
K
Sbjct: 854 K 854
Score = 294 bits (753), Expect = 1e-79
Identities = 170/399 (42%), Positives = 237/399 (59%), Gaps = 42/399 (10%)
Query: 19 DFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL----VVGRFPKEHRI--- 71
D YH +E A + A + L SIG+SV+GR LWVL +G E
Sbjct: 56 DRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPD 115
Query: 72 ------------GIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTR 118
G P+ K V NMHGDETV R++L++L L + DP + L+N+T
Sbjct: 116 AAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTD 175
Query: 119 IHIMPSMNPDGFEAVKKPDCYY-------SIGRENYNQYDLNRNFPDAF---EYNNVSRQ 168
++++PS+NPDGFE ++ DC + + GR+N DLNR+FPD F E +
Sbjct: 176 VYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPALDEV 235
Query: 169 PETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQ--ATGALYSRSLTPDDDVFQYLA 226
PE A+++W++ FVLS NLHGG++VASYPFD+ + ATG +YS+ T DD+VF+YLA
Sbjct: 236 PEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATG-IYSK--TSDDEVFKYLA 292
Query: 227 HTYASRNPNMKKGD-ECKNKMN--FPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELS 283
YAS +P MK G+ C + F +G+TNG WY ++GGMQDYNY+WA CFEITLELS
Sbjct: 293 KAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELS 352
Query: 284 CCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQ-NGNPLPNVIVEVQDRKHICP 342
CCKYP +L W NN+ SLI I++VH+GVKG V D G+ L N + V H
Sbjct: 353 CCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINH--N 410
Query: 343 YRTNKYGEYYLLLLPGSYIINVTVPGHDP-HITKVIIPE 380
T ++G++Y LL+PG+Y + V + G+ P +T V++ E
Sbjct: 411 ITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKE 449
Score = 223 bits (569), Expect = 2e-58
Identities = 123/363 (33%), Positives = 202/363 (55%), Gaps = 22/363 (6%)
Query: 20 FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
+ YH + + FL+ + NY +T+L ++G+S + R++W L + P P+ ++V
Sbjct: 931 YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFV 990
Query: 80 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139
A +HG+ VG ELLL L ++L + K+P +T L++ TRI I+PS+NPDG E ++ DC
Sbjct: 991 AGIHGNAPVGTELLLALAEFLCLNYKKNPAVTQLVDRTRIVIVPSLNPDGRERAQEKDCT 1050
Query: 140 YSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMK-WLKTETFVLSANLHGGALVASY 198
IG+ N DL+ +F NN S QPET A+++ ++ + F LS L GG+++ +Y
Sbjct: 1051 SKIGQTNARGKDLDTDFT-----NNAS-QPETKAIIENLIQKQDFSLSVALDGGSMLVTY 1104
Query: 199 PFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD-ECKNKM--NFPNGVTNG 255
P+D VQ + + ++LA YA+ +P+M G C NK N P GV G
Sbjct: 1105 PYDKPVQT---------VENKETLKHLASLYANNHPSMHMGQPSCPNKSDENIPGGVMRG 1155
Query: 256 YSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGV 315
W+ G M+DY+ + C EIT+ SCC +P +LPS W +NK SL+ + +VH GV
Sbjct: 1156 AEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADNKRSLLSMLVEVHKGV 1215
Query: 316 KGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITK 375
G V D+ G P+ ++ + + + +T + G +++LL PG + I G+ ++
Sbjct: 1216 HGFVKDKTGKPISKAVIVLNEGIKV---QTKEGGYFHVLLAPGVHNIIAIADGYQQQHSQ 1272
Query: 376 VII 378
V +
Sbjct: 1273 VFV 1275
>gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo
sapiens]
Length = 458
Score = 307 bits (787), Expect = 1e-83
Identities = 174/405 (42%), Positives = 236/405 (58%), Gaps = 42/405 (10%)
Query: 6 LWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRF 65
L L LL LVA + F +HR + + L V +T ++SIG+SV+GR+L+VL
Sbjct: 9 LHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDH 68
Query: 66 PKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTS-DGKDPEITNLINSTRIHIMPS 124
P H PE KYV NMHG+E +GREL+L L ++L ++ I LI TRIHI+PS
Sbjct: 69 PGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPS 128
Query: 125 MNPDGFEAV-----KKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSR------------ 167
MNPDG+E KP Y +GR N N DLNRNFPD Y +
Sbjct: 129 MNPDGYEVAAAQGPNKPG--YLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLP 186
Query: 168 -------QPETVAVMKWLKTETFVLSANLHGGALVASYPFDN-------GVQATGALYSR 213
+PET AV++W+ + FVLSANLHGGA+VA+YP+D GV+ T +
Sbjct: 187 DNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTAS---- 242
Query: 214 SLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWA 273
+ TPDD +FQ LA Y+ + M +G C + FP+G+TNG SWY L GMQD+NY+
Sbjct: 243 TPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDY--FPDGITNGASWYSLSKGMQDFNYLHT 300
Query: 274 QCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVE 333
CFEITLELSC K+P EE+L W N+ +LI++++QVH G+KG V D+N N L N ++
Sbjct: 301 NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS 360
Query: 334 VQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVII 378
V H + +G+Y+ LLLPG Y ++ T PG+DP V +
Sbjct: 361 VSGINH--DVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTV 403
>gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]
Length = 476
Score = 300 bits (768), Expect = 2e-81
Identities = 168/394 (42%), Positives = 229/394 (58%), Gaps = 36/394 (9%)
Query: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
+ F YHR + L +V ++++ ++++G+S +GR L V+ + P H G PEFK
Sbjct: 49 ISFEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGVHEPGEPEFK 108
Query: 78 YVANMHGDETVGRELLLHLIDYLVTSDGKDPE-ITNLINSTRIHIMPSMNPDGFE-AVKK 135
Y+ NMHG+E VGRELL+ L YL K E I NLI+STRIHIMPS+NPDGFE A +
Sbjct: 109 YIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQ 168
Query: 136 PDCY--YSIGRENYNQYDLNRNFPDAFEY-----------------------NNVSRQPE 170
P + +GR N DLNRNFPD N PE
Sbjct: 169 PGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNMKKIVDQNTKLAPE 228
Query: 171 TVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYA 230
T AV+ W+ FVLSANLHGG LVA+YP+D +G+ + S +PDD +FQ LA Y+
Sbjct: 229 TKAVIHWIMDIPFVLSANLHGGDLVANYPYDE--TRSGSAHEYSSSPDDAIFQSLARAYS 286
Query: 231 SRNPNMKKGDECKNKMN-----FPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCC 285
S NP M + + N F +G TNG +WY + GGMQD+NY+ + CFEIT+ELSC
Sbjct: 287 SFNPAMSDPNRPPCRKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCE 346
Query: 286 KYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRT 345
K+P EE L ++W +NK SLI Y++Q+H GVKG V D GNP+ N + V+ H +
Sbjct: 347 KFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANATISVEGIDH--DVTS 404
Query: 346 NKYGEYYLLLLPGSYIINVTVPGHDPHITKVIIP 379
K G+Y+ LL+PG+Y + + PG+ KV +P
Sbjct: 405 AKDGDYWRLLIPGNYKLTASAPGYLAITKKVAVP 438
>gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]
Length = 515
Score = 266 bits (681), Expect = 2e-71
Identities = 153/389 (39%), Positives = 212/389 (54%), Gaps = 30/389 (7%)
Query: 20 FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
F++H M L+ A + V +SIG+S GR L V+ P +H + PE K +
Sbjct: 48 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 107
Query: 80 ANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138
N+HG+E GRE+L++L YL + +P I L+N+TRIH++PSMNPDG+E
Sbjct: 108 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 167
Query: 139 YYS---IGRENYNQYDLNRNFPD-AFEYNNVSRQ--------------------PETVAV 174
Y+ GR+N DLNRNFPD EY ++ PET A+
Sbjct: 168 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAI 227
Query: 175 MKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNP 234
MKW++T FVLSA+LHGG LV SYPFD S TPD+ +F+ L+ YA +P
Sbjct: 228 MKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMF-SPTPDEKMFKLLSRAYADVHP 286
Query: 235 NMKKGDECKNKMNF--PNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEK 292
M E + NF + NG WY GGM D+NY+ CFEIT+EL C K+P EE
Sbjct: 287 MMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEA 346
Query: 293 LPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYY 352
L + W +NK SL+ +++ VH G+KG V D+ G P+ N + V+ +H T G+Y+
Sbjct: 347 LYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRH--DITTAPDGDYW 404
Query: 353 LLLLPGSYIINVTVPGHDPHITKVIIPEK 381
LL PG +I+ PG+ I KVIIP +
Sbjct: 405 RLLPPGIHIVIAQAPGYAKVIKKVIIPAR 433
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 266 bits (681), Expect = 2e-71
Identities = 153/389 (39%), Positives = 212/389 (54%), Gaps = 30/389 (7%)
Query: 20 FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
F++H M L+ A + V +SIG+S GR L V+ P +H + PE K +
Sbjct: 174 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 233
Query: 80 ANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138
N+HG+E GRE+L++L YL + +P I L+N+TRIH++PSMNPDG+E
Sbjct: 234 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 293
Query: 139 YYS---IGRENYNQYDLNRNFPD-AFEYNNVSRQ--------------------PETVAV 174
Y+ GR+N DLNRNFPD EY ++ PET A+
Sbjct: 294 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAI 353
Query: 175 MKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNP 234
MKW++T FVLSA+LHGG LV SYPFD S TPD+ +F+ L+ YA +P
Sbjct: 354 MKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMF-SPTPDEKMFKLLSRAYADVHP 412
Query: 235 NMKKGDECKNKMNF--PNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEK 292
M E + NF + NG WY GGM D+NY+ CFEIT+EL C K+P EE
Sbjct: 413 MMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEA 472
Query: 293 LPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYY 352
L + W +NK SL+ +++ VH G+KG V D+ G P+ N + V+ +H T G+Y+
Sbjct: 473 LYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRH--DITTAPDGDYW 530
Query: 353 LLLLPGSYIINVTVPGHDPHITKVIIPEK 381
LL PG +I+ PG+ I KVIIP +
Sbjct: 531 RLLPPGIHIVIAQAPGYAKVIKKVIIPAR 559
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 266 bits (681), Expect = 2e-71
Identities = 153/389 (39%), Positives = 212/389 (54%), Gaps = 30/389 (7%)
Query: 20 FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
F++H M L+ A + V +SIG+S GR L V+ P +H + PE K +
Sbjct: 185 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 244
Query: 80 ANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138
N+HG+E GRE+L++L YL + +P I L+N+TRIH++PSMNPDG+E
Sbjct: 245 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 304
Query: 139 YYS---IGRENYNQYDLNRNFPD-AFEYNNVSRQ--------------------PETVAV 174
Y+ GR+N DLNRNFPD EY ++ PET A+
Sbjct: 305 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAI 364
Query: 175 MKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNP 234
MKW++T FVLSA+LHGG LV SYPFD S TPD+ +F+ L+ YA +P
Sbjct: 365 MKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMF-SPTPDEKMFKLLSRAYADVHP 423
Query: 235 NMKKGDECKNKMNF--PNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEK 292
M E + NF + NG WY GGM D+NY+ CFEIT+EL C K+P EE
Sbjct: 424 MMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEA 483
Query: 293 LPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYY 352
L + W +NK SL+ +++ VH G+KG V D+ G P+ N + V+ +H T G+Y+
Sbjct: 484 LYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRH--DITTAPDGDYW 541
Query: 353 LLLLPGSYIINVTVPGHDPHITKVIIPEK 381
LL PG +I+ PG+ I KVIIP +
Sbjct: 542 RLLPPGIHIVIAQAPGYAKVIKKVIIPAR 570
>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
sapiens]
Length = 756
Score = 251 bits (642), Expect = 7e-67
Identities = 138/385 (35%), Positives = 212/385 (55%), Gaps = 37/385 (9%)
Query: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
LDF +H + M +K V + ++T +++IGKS +G L+ + + P EH +G PEF
Sbjct: 314 LDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFH 373
Query: 78 YVANMHGDETVGRELLLHLIDYLVTSD-GKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
Y+A HG+E +GRELLL L+ ++ ++ I +L+ TRIH++PS+NPDG+E +
Sbjct: 374 YIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEG 433
Query: 137 DCY---YSIGRENYNQYDLNRNFPD-------AFEYNNVSRQ------------------ 168
+S+GR ++ D+N NFPD A + NV R+
Sbjct: 434 GSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENAT 493
Query: 169 --PETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLA 226
ET AV+ W++ FVL NL GG LV +YP+D V++ + TPDD VF++LA
Sbjct: 494 VAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDL-VRSPWKTQEHTPTPDDHVFRWLA 552
Query: 227 HTYASRNPNMKKGDE--CKNK-MNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELS 283
++YAS + M C + G NG SW+ + G + D++Y+ CFE+++ +
Sbjct: 553 YSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVG 612
Query: 284 CCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPY 343
C KYP E +LP W NN+ SLI +++QVH G+KG V D +G +PN I+ V+ H
Sbjct: 613 CDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISVEGINH--DI 670
Query: 344 RTNKYGEYYLLLLPGSYIINVTVPG 368
RT G+Y+ LL PG Y++ G
Sbjct: 671 RTANDGDYWRLLNPGEYVVTAKAEG 695
>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
Length = 734
Score = 249 bits (636), Expect = 4e-66
Identities = 142/387 (36%), Positives = 211/387 (54%), Gaps = 38/387 (9%)
Query: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
LDF +H + M +K V + ++T ++SIGKS +G L+V+ + P EH +G PE +
Sbjct: 295 LDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVR 354
Query: 78 YVANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
YVA MHG+E +GRELLL L+ +L + +P +T L++ RIH++PSMNPDG+E
Sbjct: 355 YVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHR 414
Query: 137 DCY---YSIGRENYNQYDLNRNFPDA---------------------------FEYNNVS 166
++ GR N DLN NF D + N +
Sbjct: 415 GSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNAT 474
Query: 167 RQPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLA 226
PET AV+KW+K FVLSANLHGG LV SYPFD + A + TPDD VF++L+
Sbjct: 475 VAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDM-TRTPWAARELTPTPDDAVFRWLS 533
Query: 227 HTYASRNPNMKKGDE--CKNK-MNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELS 283
YA N M+ C ++ + + NG W+ + G M D++Y+ CFE+T+ELS
Sbjct: 534 TVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELS 593
Query: 284 CCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGN-PLPNVIVEVQDRKHICP 342
C K+P E +LP W NNK +L+ Y++QV +G+ G V D++ + + ++ V H
Sbjct: 594 CDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINH--D 651
Query: 343 YRTNKYGEYYLLLLPGSYIINVTVPGH 369
T G+Y+ LL PG Y++ + G+
Sbjct: 652 VTTAWGGDYWRLLTPGDYMVTASAEGY 678
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 216 bits (550), Expect = 3e-56
Identities = 137/465 (29%), Positives = 221/465 (47%), Gaps = 69/465 (14%)
Query: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
LDF +H + M +K V + ++T +S+GKS +G ++ + + P EH +G PEF+
Sbjct: 560 LDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFR 619
Query: 78 YVANMHGDETVGRELLLHLIDYLVTS--DGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
Y A +HG+E +GRELLL L+ YL DG +P + +L+ TRIH++PS+NPDG+E +
Sbjct: 620 YTAGIHGNEVLGRELLLLLMQYLCREYRDG-NPRVRSLVQDTRIHLVPSLNPDGYEVAAQ 678
Query: 136 PDCYY---SIGRENYNQYDLNRNFPDAFEY----------------NNV----------- 165
+ ++G +D+ +FPD NN+
Sbjct: 679 MGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDA 738
Query: 166 SRQPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQAT-----------------G 208
+ E A++ W++ FVL ANL+GG + SYP+D T
Sbjct: 739 TVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDED 798
Query: 209 ALYSRSLTPDDDVFQYLAHTYASRNPNMK---KGDECKNKMNFPNGVTNGYSWYPLQGGM 265
+ TPD +F++LA ++AS + + +G G+ NG W P G +
Sbjct: 799 EVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTI 858
Query: 266 QDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGN 325
D++Y+ C E++ L C K+P E +LP W NNK +L+ +++QVH G+KG V D+ G
Sbjct: 859 NDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGI 918
Query: 326 PLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPH-----------IT 374
P+ N + V H +T G+Y+ +L PG Y + G+ P T
Sbjct: 919 PIANATISVSGINH--GVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGAT 976
Query: 375 KVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNL 419
+ N+ +++ ++ G IP +PS PM P R L
Sbjct: 977 QCNFILARSNWKRIRE--IMAMNGN-RPIPHIDPSRPMTPQQRRL 1018
>gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]
Length = 437
Score = 54.3 bits (129), Expect = 2e-07
Identities = 46/200 (23%), Positives = 86/200 (43%), Gaps = 25/200 (12%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
YH E ++ ++ + + +S + H+ SIG+S +GR+L++L +GR + R +
Sbjct: 139 YHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWID----CG 194
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
+H E +G + + + DP + ++N +IMP N DG+ D ++
Sbjct: 195 IHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWR 254
Query: 142 IGRENYNQY-----DLNRNF--------------PDAFEYNNVSRQPETVAVMKWLKTET 182
R +++ D NRN+ D + +PE AV +L+
Sbjct: 255 KTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHR 314
Query: 183 FVLSANL--HGGALVASYPF 200
+ A L H A + YP+
Sbjct: 315 KHIRAYLSFHAYAQMLLYPY 334
>gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]
Length = 193
Score = 47.8 bits (112), Expect = 2e-05
Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 9/125 (7%)
Query: 37 QNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHL 96
+ +S + H+ SIG+S +GR+L++L +GR + R + +H E +G
Sbjct: 6 KTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWID----CGIHAREWIGPAFCQWF 61
Query: 97 IDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQY-----D 151
+ + + DP + ++N +IMP N DG+ D ++ R +++ D
Sbjct: 62 VKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVD 121
Query: 152 LNRNF 156
NRN+
Sbjct: 122 ANRNW 126
>gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo
sapiens]
Length = 417
Score = 45.8 bits (107), Expect = 8e-05
Identities = 56/282 (19%), Positives = 107/282 (37%), Gaps = 42/282 (14%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Y++ E +EA+ + VA ++ IG + +GR +++L VG+ + P
Sbjct: 119 YNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDCG 174
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
H E + + V + G++ ++T L++ +++P +N DG+ ++
Sbjct: 175 FHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWR 234
Query: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182
R + D NRNF + SR P ET A+ +++ +
Sbjct: 235 KTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKL 294
Query: 183 FVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240
+ A +H + + YP+ Y+ L ++ LA ++
Sbjct: 295 SSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH--- 342
Query: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
K + G T + YP GG D+ Y + T EL
Sbjct: 343 --GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 379
>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
Length = 421
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/115 (24%), Positives = 53/115 (46%), Gaps = 6/115 (5%)
Query: 19 DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
+FNY +EA + +A ++ + IG S + R ++VL +F + P
Sbjct: 117 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVL---KFSTGKGVRRPA 173
Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
A +H E + + + +V+ +DP IT+++ I ++P NPDG+
Sbjct: 174 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGY 228
>gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]
Length = 403
Score = 44.3 bits (103), Expect = 2e-04
Identities = 42/203 (20%), Positives = 80/203 (39%), Gaps = 30/203 (14%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
+YH E + +++ +S + IG S + +++ VL H P
Sbjct: 138 SYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRH----PAIWIDT 193
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
+H E + + + +V+ GKD +T+++N+ I I NPDGF +
Sbjct: 194 GIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMN--- 250
Query: 141 SIGRENYN--------QYDLNRNFPDAFEYN--------------NVSRQPETVAVMKWL 178
+ R+N + DLNRN+ F N + +PE A++ ++
Sbjct: 251 RLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFI 310
Query: 179 KTE-TFVLSANLHGGALVASYPF 200
F ++H + + YP+
Sbjct: 311 TAHGNFKALISIHSYSQMLMYPY 333
>gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 44.3 bits (103), Expect = 2e-04
Identities = 42/203 (20%), Positives = 80/203 (39%), Gaps = 30/203 (14%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
+YH E + +++ +S + IG S + +++ VL H P
Sbjct: 138 SYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRH----PAIWIDT 193
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
+H E + + + +V+ GKD +T+++N+ I I NPDGF +
Sbjct: 194 GIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMN--- 250
Query: 141 SIGRENYN--------QYDLNRNFPDAFEYN--------------NVSRQPETVAVMKWL 178
+ R+N + DLNRN+ F N + +PE A++ ++
Sbjct: 251 RLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFI 310
Query: 179 KTE-TFVLSANLHGGALVASYPF 200
F ++H + + YP+
Sbjct: 311 TAHGNFKALISIHSYSQMLMYPY 333
>gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 44.3 bits (103), Expect = 2e-04
Identities = 42/203 (20%), Positives = 80/203 (39%), Gaps = 30/203 (14%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
+YH E + +++ +S + IG S + +++ VL H P
Sbjct: 138 SYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRH----PAIWIDT 193
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
+H E + + + +V+ GKD +T+++N+ I I NPDGF +
Sbjct: 194 GIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMN--- 250
Query: 141 SIGRENYN--------QYDLNRNFPDAFEYN--------------NVSRQPETVAVMKWL 178
+ R+N + DLNRN+ F N + +PE A++ ++
Sbjct: 251 RLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFI 310
Query: 179 KTE-TFVLSANLHGGALVASYPF 200
F ++H + + YP+
Sbjct: 311 TAHGNFKALISIHSYSQMLMYPY 333
>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
sapiens]
Length = 419
Score = 43.5 bits (101), Expect = 4e-04
Identities = 28/109 (25%), Positives = 51/109 (46%), Gaps = 5/109 (4%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
YH E + + + + + +IG S + R + VL + I + A
Sbjct: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLD-----AG 177
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
+H E V + L + +V+ GKDP IT+++++ I ++P NPDG+
Sbjct: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGY 226
>gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
[Homo sapiens]
Length = 423
Score = 37.0 bits (84), Expect = 0.036
Identities = 33/140 (23%), Positives = 60/140 (42%), Gaps = 8/140 (5%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
YH + ++++ + + + + IG S + L+VL V + + I
Sbjct: 123 YHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI---WIDCG 179
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
+H E + L I ++ G + TNL+ ++MP +N DG++ K + +
Sbjct: 180 IHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWR 239
Query: 142 IGRENY-NQY----DLNRNF 156
R Y N + DLNRNF
Sbjct: 240 KNRSFYANNHCIGTDLNRNF 259
>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
Length = 417
Score = 35.0 bits (79), Expect = 0.14
Identities = 31/140 (22%), Positives = 58/140 (41%), Gaps = 9/140 (6%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Y+ E + A+ + + Y + IG +V+ L+VL +G + + +
Sbjct: 119 YNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTD----CG 174
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF-EAVKKPDCYY 140
+H E V + + G++ +T L++ +I+P N DG+ + K +
Sbjct: 175 IHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWR 234
Query: 141 SIGRENYNQ----YDLNRNF 156
+N N DLNRNF
Sbjct: 235 KNRSKNQNSKCIGTDLNRNF 254
>gi|27436871 carboxypeptidase O [Homo sapiens]
Length = 374
Score = 33.9 bits (76), Expect = 0.30
Identities = 34/182 (18%), Positives = 74/182 (40%), Gaps = 28/182 (15%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV-- 79
YH + +++ +++ Y V H +G + + ++ L + + G P+ K +
Sbjct: 50 YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQ-----PSGNPK-KIIWM 103
Query: 80 -ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138
+H E + + ++ + + I L+ + +++P +N DG+ D
Sbjct: 104 DCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDR 163
Query: 139 YYSIGRENYNQ-----YDLNRNFPDAFEYNNVSR--------------QPETVAVMKWLK 179
+ R +N DLNRNF ++ SR +PET AV +++
Sbjct: 164 LWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIE 223
Query: 180 TE 181
++
Sbjct: 224 SK 225
>gi|157388919 homolog of yeast tRNA methyltransferase 12 [Homo
sapiens]
Length = 448
Score = 30.8 bits (68), Expect = 2.6
Identities = 14/45 (31%), Positives = 23/45 (51%)
Query: 25 QEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEH 69
+EG + + Q+ + H+H +S G+NL L V + KEH
Sbjct: 315 EEGWPIACQVLRQDAGGILHIHQNVESFPGKNLQALGVSKVEKEH 359
>gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
Length = 419
Score = 30.4 bits (67), Expect = 3.4
Identities = 36/154 (23%), Positives = 60/154 (38%), Gaps = 11/154 (7%)
Query: 22 YHRQEGMEAFLKT-VAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
YH E + FL VA+N V+ + IG + +GR ++VL + P
Sbjct: 122 YHTLEEIYDFLDLLVAENPHLVSKIQ-IGNTYEGRPIYVLKFSTGGSKR----PAIWIDT 176
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
+H E V + + + G+D T ++++ I + NPDGF + +
Sbjct: 177 GIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMW 236
Query: 141 SIGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169
R + D NRN+ F + S P
Sbjct: 237 RKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNP 270
>gi|194097335 lipase C precursor [Homo sapiens]
Length = 499
Score = 29.6 bits (65), Expect = 5.7
Identities = 32/145 (22%), Positives = 57/145 (39%), Gaps = 23/145 (15%)
Query: 170 ETVAVMKWLKTETFVLSANLHG-----GALVASYPFDN-----------GVQATGALY-- 211
E A+++WL+ + +++H GA V+ + + G+ A G L+
Sbjct: 143 EVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLFEG 202
Query: 212 ---SRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDY 268
S L+PDD F HT+ + + G K + + NG S+ P ++ Y
Sbjct: 203 SAPSNRLSPDDANFVDAIHTFTREHMGLSVG--IKQPIGHYDFYPNGGSFQPGCHFLELY 260
Query: 269 NYIWAQCFEITLELSCCKYPREEKL 293
+I F + C + R L
Sbjct: 261 RHIAQHGFNAITQTIKCSHERSVHL 285
>gi|239787844 testis expressed 10 isoform 2 [Homo sapiens]
Length = 913
Score = 29.6 bits (65), Expect = 5.7
Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 2/61 (3%)
Query: 376 VIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLV 435
++IP +SQNF L+ I G L IP S C + + L DH+ +L FL
Sbjct: 744 LVIPARSQNFDILQSAISKHLVG-LTVIPDSTAGC-VFGVICKLLDHTCVVSETLLPFLA 801
Query: 436 S 436
S
Sbjct: 802 S 802
>gi|239787838 testis expressed 10 isoform 1 [Homo sapiens]
Length = 929
Score = 29.6 bits (65), Expect = 5.7
Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 2/61 (3%)
Query: 376 VIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLV 435
++IP +SQNF L+ I G L IP S C + + L DH+ +L FL
Sbjct: 741 LVIPARSQNFDILQSAISKHLVG-LTVIPDSTAGC-VFGVICKLLDHTCVVSETLLPFLA 798
Query: 436 S 436
S
Sbjct: 799 S 799
>gi|157266292 intestinal alkaline phosphatase precursor [Homo
sapiens]
Length = 528
Score = 28.9 bits (63), Expect = 9.8
Identities = 12/34 (35%), Positives = 20/34 (58%)
Query: 278 ITLELSCCKYPREEKLPSFWNNNKASLIEYIKQV 311
+ L+LS P EE+ P+FWN A ++ K++
Sbjct: 12 LRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKL 45
>gi|20270323 zinc finger protein 653 [Homo sapiens]
Length = 615
Score = 28.9 bits (63), Expect = 9.8
Identities = 11/22 (50%), Positives = 15/22 (68%)
Query: 322 QNGNPLPNVIVEVQDRKHICPY 343
+N N L NV++ +D KH CPY
Sbjct: 118 RNVNCLKNVVIWYEDHKHRCPY 139
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.139 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,058,398
Number of Sequences: 37866
Number of extensions: 824055
Number of successful extensions: 1642
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1548
Number of HSP's gapped (non-prelim): 39
length of query: 443
length of database: 18,247,518
effective HSP length: 105
effective length of query: 338
effective length of database: 14,271,588
effective search space: 4823796744
effective search space used: 4823796744
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.