Search of human proteins with 52630445

Search of human proteins with 52630445

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|52630445 monocyte to macrophage differentiation-associated
precursor [Homo sapiens]
         (238 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|52630445 monocyte to macrophage differentiation-associated pr...   510   e-145
gi|154759275 monocyte to macrophage differentiation-associated 2...   365   e-101
gi|154759277 monocyte to macrophage differentiation-associated 2...   352   2e-97
gi|118600969 C-type lectin domain family 17, member A [Homo sapi...    30   1.4  
gi|210147409 sphingomyelin synthase 2 [Homo sapiens]                   30   1.8  
gi|210147407 sphingomyelin synthase 2 [Homo sapiens]                   30   1.8  
gi|22749271 sphingomyelin synthase 2 [Homo sapiens]                    30   1.8  

>gi|52630445 monocyte to macrophage differentiation-associated
           precursor [Homo sapiens]
          Length = 238

 Score =  510 bits (1314), Expect = e-145
 Identities = 238/238 (100%), Positives = 238/238 (100%)

Query: 1   MRFKNRFQRFMNHRAPANGRYKPTCYEHAANCYTHAFLIVPAIVGSALLHRLSDDCWEKI 60
           MRFKNRFQRFMNHRAPANGRYKPTCYEHAANCYTHAFLIVPAIVGSALLHRLSDDCWEKI
Sbjct: 1   MRFKNRFQRFMNHRAPANGRYKPTCYEHAANCYTHAFLIVPAIVGSALLHRLSDDCWEKI 60

Query: 61  TAWIYGMGLCALFIVSTVFHIVSWKKSHLRTVEHCFHMCDRMVIYFFIAASYAPWLNLRE 120
           TAWIYGMGLCALFIVSTVFHIVSWKKSHLRTVEHCFHMCDRMVIYFFIAASYAPWLNLRE
Sbjct: 61  TAWIYGMGLCALFIVSTVFHIVSWKKSHLRTVEHCFHMCDRMVIYFFIAASYAPWLNLRE 120

Query: 121 LGPLASHMRWFIWLMAAGGTIYVFLYHEKYKVVELFFYLTMGFSPALVVTSMNNTDGLQE 180
           LGPLASHMRWFIWLMAAGGTIYVFLYHEKYKVVELFFYLTMGFSPALVVTSMNNTDGLQE
Sbjct: 121 LGPLASHMRWFIWLMAAGGTIYVFLYHEKYKVVELFFYLTMGFSPALVVTSMNNTDGLQE 180

Query: 181 LACGGLIYCLGVVFFKSDGIIPFAHAIWHLFVATAAAVHYYAIWKYLYRSPTDFMRHL 238
           LACGGLIYCLGVVFFKSDGIIPFAHAIWHLFVATAAAVHYYAIWKYLYRSPTDFMRHL
Sbjct: 181 LACGGLIYCLGVVFFKSDGIIPFAHAIWHLFVATAAAVHYYAIWKYLYRSPTDFMRHL 238


>gi|154759275 monocyte to macrophage differentiation-associated 2
           isoform 2 [Homo sapiens]
          Length = 246

 Score =  365 bits (937), Expect = e-101
 Identities = 165/229 (72%), Positives = 191/229 (83%)

Query: 4   KNRFQRFMNHRAPANGRYKPTCYEHAANCYTHAFLIVPAIVGSALLHRLSDDCWEKITAW 63
           K ++ RFMNHR PA+ RY+PT YEHAANC THAF I+P+I+GS+ L+ LSDD WE I+AW
Sbjct: 11  KTKYARFMNHRVPAHKRYQPTEYEHAANCATHAFWIIPSILGSSNLYFLSDDDWETISAW 70

Query: 64  IYGMGLCALFIVSTVFHIVSWKKSHLRTVEHCFHMCDRMVIYFFIAASYAPWLNLRELGP 123
           IYG+GLC LF+VSTVFH +SWKKSHLR VEHC HM DRMVIYFFIAASYAPWLNLRELGP
Sbjct: 71  IYGLGLCGLFVVSTVFHTISWKKSHLRMVEHCLHMFDRMVIYFFIAASYAPWLNLRELGP 130

Query: 124 LASHMRWFIWLMAAGGTIYVFLYHEKYKVVELFFYLTMGFSPALVVTSMNNTDGLQELAC 183
            ASHMRW +W+MA+ GTIYVF +HE+YK+VEL  Y+ MGF PALV+ SM NT+G+ EL  
Sbjct: 131 WASHMRWLVWIMASVGTIYVFFFHERYKLVELLCYVVMGFFPALVILSMPNTEGIWELVT 190

Query: 184 GGLIYCLGVVFFKSDGIIPFAHAIWHLFVATAAAVHYYAIWKYLYRSPT 232
           GG+ YCLG+VFFKSDG IPFAHAIWHLFVA  A  HYYAIW+YLY   T
Sbjct: 191 GGVFYCLGMVFFKSDGRIPFAHAIWHLFVAFGAGTHYYAIWRYLYLPST 239


>gi|154759277 monocyte to macrophage differentiation-associated 2
           isoform 1 [Homo sapiens]
          Length = 270

 Score =  352 bits (902), Expect = 2e-97
 Identities = 165/253 (65%), Positives = 191/253 (75%), Gaps = 24/253 (9%)

Query: 4   KNRFQRFMNHRAPANGRYKPTCYEHAANCYTHAFLIVPAIVGSALLHRLSDDCWEKITAW 63
           K ++ RFMNHR PA+ RY+PT YEHAANC THAF I+P+I+GS+ L+ LSDD WE I+AW
Sbjct: 11  KTKYARFMNHRVPAHKRYQPTEYEHAANCATHAFWIIPSILGSSNLYFLSDDDWETISAW 70

Query: 64  IYGMGLCALFIVSTVFHIVSWKKSHLRTVEHCFHMCDRMVIYFFIAASYAPWLNLRELGP 123
           IYG+GLC LF+VSTVFH +SWKKSHLR VEHC HM DRMVIYFFIAASYAPWLNLRELGP
Sbjct: 71  IYGLGLCGLFVVSTVFHTISWKKSHLRMVEHCLHMFDRMVIYFFIAASYAPWLNLRELGP 130

Query: 124 LASHMRWFIWLMAAGGTIYVFLYHE------------------------KYKVVELFFYL 159
            ASHMRW +W+MA+ GTIYVF +HE                        +YK+VEL  Y+
Sbjct: 131 WASHMRWLVWIMASVGTIYVFFFHERTGSCVQFLRGEACPKAGTACLPARYKLVELLCYV 190

Query: 160 TMGFSPALVVTSMNNTDGLQELACGGLIYCLGVVFFKSDGIIPFAHAIWHLFVATAAAVH 219
            MGF PALV+ SM NT+G+ EL  GG+ YCLG+VFFKSDG IPFAHAIWHLFVA  A  H
Sbjct: 191 VMGFFPALVILSMPNTEGIWELVTGGVFYCLGMVFFKSDGRIPFAHAIWHLFVAFGAGTH 250

Query: 220 YYAIWKYLYRSPT 232
           YYAIW+YLY   T
Sbjct: 251 YYAIWRYLYLPST 263


>gi|118600969 C-type lectin domain family 17, member A [Homo
           sapiens]
          Length = 289

 Score = 30.4 bits (67), Expect = 1.4
 Identities = 12/27 (44%), Positives = 16/27 (59%)

Query: 108 IAASYAPWLNLRELGPLASHMRWFIWL 134
           +AA+  PWLN R  GP     RW ++L
Sbjct: 130 LAATPVPWLNQRSGGPGCCQKRWMVYL 156


>gi|210147409 sphingomyelin synthase 2 [Homo sapiens]
          Length = 365

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 6/50 (12%)

Query: 115 WLNLRELGPLASHMRWF---IWLMAAGGTIYVFLYHEKYKV-VELFFYLT 160
           +L ++E  P   H  W+    WL++A G I + + HE Y + V + +Y+T
Sbjct: 237 YLFIKEYSP--RHFWWYHLICWLLSAAGIICILVAHEHYTIDVIIAYYIT 284


>gi|210147407 sphingomyelin synthase 2 [Homo sapiens]
          Length = 365

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 6/50 (12%)

Query: 115 WLNLRELGPLASHMRWF---IWLMAAGGTIYVFLYHEKYKV-VELFFYLT 160
           +L ++E  P   H  W+    WL++A G I + + HE Y + V + +Y+T
Sbjct: 237 YLFIKEYSP--RHFWWYHLICWLLSAAGIICILVAHEHYTIDVIIAYYIT 284


>gi|22749271 sphingomyelin synthase 2 [Homo sapiens]
          Length = 365

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 6/50 (12%)

Query: 115 WLNLRELGPLASHMRWF---IWLMAAGGTIYVFLYHEKYKV-VELFFYLT 160
           +L ++E  P   H  W+    WL++A G I + + HE Y + V + +Y+T
Sbjct: 237 YLFIKEYSP--RHFWWYHLICWLLSAAGIICILVAHEHYTIDVIIAYYIT 284


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.333    0.142    0.494 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,372,958
Number of Sequences: 37866
Number of extensions: 382467
Number of successful extensions: 1075
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1070
Number of HSP's gapped (non-prelim): 7
length of query: 238
length of database: 18,247,518
effective HSP length: 99
effective length of query: 139
effective length of database: 14,498,784
effective search space: 2015330976
effective search space used: 2015330976
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.5 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.