Search of human proteins with 51873064

Search of human proteins with 51873064

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51873064 mannosidase, alpha, class 2B, member 1 precursor
[Homo sapiens]
         (1011 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51873064 mannosidase, alpha, class 2B, member 1 precursor [Ho...  2088   0.0  
gi|50659093 mannosidase, alpha, class 2B, member 2 [Homo sapiens]     310   6e-84
gi|51477716 mannosidase, alpha, class 2A, member 2 [Homo sapiens]     287   3e-77
gi|51477714 mannosidase, alpha, class 2A, member 1 [Homo sapiens]     280   6e-75
gi|211971038 tousled-like kinase 1 isoform 3 [Homo sapiens]            35   0.47 
gi|211971036 tousled-like kinase 1 isoform 2 [Homo sapiens]            35   0.47 
gi|33636698 tousled-like kinase 1 isoform 1 [Homo sapiens]             35   0.47 
gi|31652264 RNA binding motif protein 26 [Homo sapiens]                33   1.8  
gi|124430752 kinesin family member 26B [Homo sapiens]                  31   5.2  
gi|7661880 centaurin beta1 [Homo sapiens]                              31   6.7  
gi|116292178 hypothetical protein LOC414918 [Homo sapiens]             31   6.7  
gi|30578412 potassium channel tetramerisation domain containing ...    30   8.8  

>gi|51873064 mannosidase, alpha, class 2B, member 1 precursor [Homo
            sapiens]
          Length = 1011

 Score = 2088 bits (5409), Expect = 0.0
 Identities = 1011/1011 (100%), Positives = 1011/1011 (100%)

Query: 1    MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARAGGYETCPTVQP 60
            MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARAGGYETCPTVQP
Sbjct: 1    MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARAGGYETCPTVQP 60

Query: 61   NMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVE 120
            NMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVE
Sbjct: 61   NMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVE 120

Query: 121  IAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLE 180
            IAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLE
Sbjct: 121  IAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLE 180

Query: 181  DTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWR 240
            DTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWR
Sbjct: 181  DTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWR 240

Query: 241  ASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVA 300
            ASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVA
Sbjct: 241  ASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVA 300

Query: 301  TAQGRYYRTNHTVMTMGSDFQYENANMWFKNLDKLIRLVNAQQAKGSSVHVLYSTPACYL 360
            TAQGRYYRTNHTVMTMGSDFQYENANMWFKNLDKLIRLVNAQQAKGSSVHVLYSTPACYL
Sbjct: 301  TAQGRYYRTNHTVMTMGSDFQYENANMWFKNLDKLIRLVNAQQAKGSSVHVLYSTPACYL 360

Query: 361  WELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVG 420
            WELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVG
Sbjct: 361  WELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVG 420

Query: 421  LAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNAL 480
            LAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNAL
Sbjct: 421  LAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNAL 480

Query: 481  ARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDP 540
            ARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDP
Sbjct: 481  ARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDP 540

Query: 541  NGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSVAQVPRWKPQARAPQPIPRRS 600
            NGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSVAQVPRWKPQARAPQPIPRRS
Sbjct: 541  NGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSVAQVPRWKPQARAPQPIPRRS 600

Query: 601  WSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAY 660
            WSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAY
Sbjct: 601  WSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAY 660

Query: 661  IFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIP 720
            IFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIP
Sbjct: 661  IFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIP 720

Query: 721  VGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNT 780
            VGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNT
Sbjct: 721  VGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNT 780

Query: 781  RIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRG 840
            RIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRG
Sbjct: 781  RIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRG 840

Query: 841  RHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSV 900
            RHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSV
Sbjct: 841  RHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSV 900

Query: 901  HLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQ 960
            HLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQ
Sbjct: 901  HLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQ 960

Query: 961  LREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG 1011
            LREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG
Sbjct: 961  LREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG 1011


>gi|50659093 mannosidase, alpha, class 2B, member 2 [Homo sapiens]
          Length = 1009

 Score =  310 bits (793), Expect = 6e-84
 Identities = 304/1068 (28%), Positives = 464/1068 (43%), Gaps = 164/1068 (15%)

Query: 34   PLCFFLLLLAAAGARAGGYETCPTVQPNMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQ 93
            PL   LLLL   G ++ G           +   ++PH+H DVGW+ TV +          
Sbjct: 8    PLLAPLLLLRPPGVQSAG----------PIRAFVVPHSHMDVGWVYTVQESM-------- 49

Query: 94   HAGVQYILDSVISALLADPTRRFIYVEIAFFSRWWHQQTNATQEV-VRDLVRQGRLEFAN 152
             A    +  SV+  L     RRFI VE  FF  WW    +  Q+  VR L+ +GRLEF  
Sbjct: 50   RAYAANVYTSVVEELARGQQRRFIAVEQEFFRLWWDGVASDQQKYQVRQLLEEGRLEFVI 109

Query: 153  GGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDPFGHSREQASLFAQMG 212
            GG VM+DEA TH    + Q+T G  FL +TFG   RP+ +WH+DPFG S    +LFA  G
Sbjct: 110  GGQVMHDEAVTHLDDQILQLTEGHGFLYETFGI--RPQFSWHVDPFGASATTPTLFALAG 167

Query: 213  FDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVLPN-GYNPPRNL---- 267
            F+     R+DY  K    +   ++ VWR S SL     ++FT ++    Y  P ++    
Sbjct: 168  FNAHLGSRIDYDLKAAMQEARGLQFVWRGSPSLS-ERQEIFTHIMDQYSYCTPSHIPFSN 226

Query: 268  ----CWDVLCV--------DQPLVEDPRSPEYNAKELVDYFLNVATAQGRYYRTNHTVMT 315
                 W+ + V          P + +P +P  N     +  +     +  ++RT H +  
Sbjct: 227  RSGFYWNGVAVFPKPPQDGVYPNMSEPVTPA-NINLYAEALVANVKQRAAWFRTPHVLWP 285

Query: 316  MGSDFQYENANMWFKNLDKLIRLVNAQQAKGSSVHVLYSTPACYLWELNKANLTWSVK-H 374
             G D Q+ NA++ F N+D L+  +N+  A+   V V Y+T   Y   L+  N+TW V+ H
Sbjct: 286  WGCDKQFFNASVQFANMDPLLDHINSHAAE-LGVSVQYATLGDYFRALHALNVTWRVRDH 344

Query: 375  DDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVGLAANVG----PYGS 430
             DF PY+  P Q WTG+++SR +LK   R +   L     +       A  G     +  
Sbjct: 345  HDFLPYSTEPFQAWTGFYTSRSSLKGLARRASALLYAGESMFTRYLWPAPRGHLDPTWAL 404

Query: 431  GDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGW-GPCEVLLSNALARLRGFKDH 489
                 L  A++ +QHHDA++GT    V + YA  LA+G  G  +++ S  L  L+     
Sbjct: 405  QQLQQLRWAVSEVQHHDAITGTESPKVRDMYATHLASGMLGMRKLMASIVLDELQ----- 459

Query: 490  FTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDPNGRTVPSDV 549
                 Q  ++    +  A  F   VYNPL   V  +V L V      V D  G  VPS +
Sbjct: 460  ----PQAPMAASSDAGPAGHF-ASVYNPLAWTVTTIVTLTVGFPGVRVTDEAGHPVPSQI 514

Query: 550  VIFPSSDSQAHPPELLFSASLPALGFSTYSV-----AQVPRWKPQARAPQPIP-----RR 599
                +S       +LL   ++P L +  Y++     AQ    +P A     +      RR
Sbjct: 515  ---QNSTETPSAYDLLILTTIPGLSYRHYNIRPTAGAQEGTQEPAATVASTLQFGRRLRR 571

Query: 600  SWSPA----LTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQ 655
              S A    + + N+      D DT L+  I        + V Q F  Y+ + GD +   
Sbjct: 572  RTSHAGRYLVPVANDCYIVLLDQDTNLMHSIWERQSNRTVRVTQEFLEYHVN-GDVKQGP 630

Query: 656  ASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNF----------SAWCSQVVRLYP 705
             S  Y+F P  +  +P     ++ +V   LV E+ Q F           A  S++  +  
Sbjct: 631  ISDNYLFTPG-KAAVPAWEAVEMEIVAGQLVTEIRQYFYRNMTAQNYTYAIRSRLTHVPQ 689

Query: 706  GQ------RHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDY 759
            G         +E E+  GP+ +     +E + R  T L ++   Y+D+NG ++  +RR Y
Sbjct: 690  GHDGELLCHRIEQEYQAGPLEL----NREAVLRTSTNLNSQQVIYSDNNGYQM--QRRPY 743

Query: 760  RPTWKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRL-- 817
                 +N +  +A NYYP+    ++ DG  +L +L++R+ G SS  +G +E+M+HRRL  
Sbjct: 744  --VSYVNNS--IARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWN 799

Query: 818  ---------LKDDGRGVSEPLMENGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQ 868
                     L  +   V  P++    G+W        L    A A  HR         P 
Sbjct: 800  NFDWDLGYNLTLNDTSVVHPVLWLLLGSW---SLTTALRQRSALALQHR---------PV 847

Query: 869  VVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSVHL--LTLASW------------------ 908
            V+     G A  L  P + +       LPP++HL  L++  W                  
Sbjct: 848  VLFGDLAGTAPKLPGPQQQE----AVTLPPNLHLQILSIPGWRYSSNHTEHSQNLRKGHR 903

Query: 909  -----GPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTF-TITRLQETTLVANQLR 962
                     VLLRL H + VGED    LS PVT+NL  +     ++  ++E +L      
Sbjct: 904  GEAQADLRRVLLRLYHLYEVGEDP--VLSQPVTVNLEAVLQALGSVVAVEERSLTGTW-- 959

Query: 963  EAASRLKWTTNTGPTPHQ---TPYQLDPAN--ITLEPMEIRTFLASVQ 1005
            + +   +W+  TGP  H+   T     P    IT+ P EIRTF    Q
Sbjct: 960  DLSMLHRWSWRTGPGRHRGDTTSPSRPPGGPIITVHPKEIRTFFIHFQ 1007


>gi|51477716 mannosidase, alpha, class 2A, member 2 [Homo sapiens]
          Length = 1150

 Score =  287 bits (735), Expect = 3e-77
 Identities = 288/1037 (27%), Positives = 445/1037 (42%), Gaps = 156/1037 (15%)

Query: 63   LNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVEIA 122
            L V ++PH+H+D GW+KT D+Y+            Q+IL+S++S L  DP RRF++ E++
Sbjct: 166  LQVFVVPHSHNDPGWIKTFDKYYT--------EQTQHILNSMVSKLQEDPRRRFLWAEVS 217

Query: 123  FFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDT 182
            FF++WW       +  VR LV  G+LE A GGWVM DEA +HY A++DQ+  G ++LE  
Sbjct: 218  FFAKWWDNINVQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERN 277

Query: 183  FGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRAS 242
             G    PR  W +DPFG+S     L  +         R+ Y  K        +E +WR +
Sbjct: 278  LG--ATPRSGWAVDPFGYSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQT 335

Query: 243  TSLKPPTADLFTGVLP-NGYNPPRNLCWD--VLC-----------VDQPLVEDPRS-PEY 287
                  T D+F  ++P   Y+ P     D  + C           ++ P    PR+  E 
Sbjct: 336  WDSDSST-DIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAITEA 394

Query: 288  NAKELVDYFLNVATAQGRYYRTNHTVMTMGSDFQYENANMW---FKNLDKLIRLVNAQQA 344
            N  E     L+    + + +R+N  ++ +G DF+Y+    W   F N  +L    N++  
Sbjct: 395  NVAERAALLLDQYRKKSQLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSR-- 452

Query: 345  KGSSVHVLYSTPACYLWELNKANLT--------WSVKHDDFFPYADGPHQFWTGYFSSRP 396
                V   + T + Y   L K            + V   DFF YAD    +WTGY++SRP
Sbjct: 453  PNLHVQAQFGTLSDYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRP 512

Query: 397  ALKRYERLSYNFLQVCNQLEALVGLAAN----VGPYGSGDSAPLNEA---MAVLQHHDAV 449
              K  +R+    L+    L +L    A      G Y   D   L EA   + + QHHDA+
Sbjct: 513  FYKSLDRVLEAHLRGAEVLYSLAAAHARRSGLAGRYPLSDFTLLTEARRTLGLFQHHDAI 572

Query: 450  SGTSRQHVANDY-ARQLAAGWGPCEVLLSNALARLRGFKDHFTFCQQ---LNISICPLSQ 505
            +GT+++ V  DY  R L +     +V++  A   + G K+ + F  +   L +    LS 
Sbjct: 573  TGTAKEAVVVDYGVRLLRSLVNLKQVIIHAAHYLVLGDKETYHFDPEAPFLQVDDTRLSH 632

Query: 506  TA------------ARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDPNGRTVPSDVVIFP 553
             A             RF V+++NPL ++   MV L V+     V    G+ +   +    
Sbjct: 633  DALPERTVIQLDSSPRF-VVLFNPLEQERFSMVSLLVNSPRVRVLSEEGQPLAVQISAHW 691

Query: 554  SSDSQAHPP--ELLFSASLPALGFSTYSV---AQVPRWKPQA------------RAPQPI 596
            SS ++A P   ++     LPALG     +       R  P +               +  
Sbjct: 692  SSATEAVPDVYQVSVPVRLPALGLGVLQLQLGLDGHRTLPSSVRIYLHGRQLSVSRHEAF 751

Query: 597  PRR---SWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNES 653
            P R   S +    + N +++  F   TGLL  I  ++++    V      Y    G   S
Sbjct: 752  PLRVIDSGTSDFALSNRYMQVWFSGLTGLLKSIRRVDEEHEQQVDMQVLVY----GTRTS 807

Query: 654  DQASGAYIFRPN-QQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLY--PGQRHL 710
               SGAY+F P+ + KP        + + + P   EV   +     Q VRLY  PG   L
Sbjct: 808  KDKSGAYLFLPDGEAKPYVPKEPPVLRVTEGPFFSEVVAYYE-HIHQAVRLYNLPGVEGL 866

Query: 711  ELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEP 770
             L+ S   + + D   KE+     T ++++G F+TD NG ++  RR          +  P
Sbjct: 867  SLDIS-SLVDIRDYVNKELALHIHTDIDSQGIFFTDLNGFQVQPRR--------YLKKLP 917

Query: 771  VAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLM 830
            +  N+YP+    YI D   +LT+ T ++ G SSL+DG LE+++ RRL++DD RG+ + L 
Sbjct: 918  LQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVILDRRLMQDDNRGLGQGLK 977

Query: 831  ENGS--------------GAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGG 876
            +N                G+ V+  H     T+  +   H  L    + AP + L     
Sbjct: 978  DNKRTCNRFRLLLERRTVGSEVQDSH----STSYPSLLSH--LTSMYLNAPALALPV--- 1028

Query: 877  AAYNLGAPPRTQFSGLRRDLPPSVHLLTLASW--------GPEMVLLRLEHQFAVGEDSG 928
            A   L  P    F  L   LP   HLL L +           E  L+     F  G ++ 
Sbjct: 1029 ARMQLPGPGLRSFHPLASSLPCDFHLLNLRTLQAEEDTLPSAETALILHRKGFDCGLEA- 1087

Query: 929  RNLSAPVTLN-----LRDLFSTFTITRLQETTLVANQLREAASRLKWTTNTGPTPHQTPY 983
            +NL    T +     L  LF    +  LQ T+L                 T   P  +P 
Sbjct: 1088 KNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSL-----------------TLLYPLASP- 1129

Query: 984  QLDPANITLEPMEIRTF 1000
              +  ++ LEPMEI TF
Sbjct: 1130 -SNSTDVYLEPMEIATF 1145


>gi|51477714 mannosidase, alpha, class 2A, member 1 [Homo sapiens]
          Length = 1144

 Score =  280 bits (715), Expect = 6e-75
 Identities = 272/1027 (26%), Positives = 448/1027 (43%), Gaps = 142/1027 (13%)

Query: 63   LNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVEIA 122
            L V ++PH+H+D GWLKT + YF            QYI ++++  L  D  R+FI+ EI+
Sbjct: 166  LQVFVVPHSHNDPGWLKTFNDYF--------RDKTQYIFNNMVLKLKEDSRRKFIWSEIS 217

Query: 123  FFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDT 182
            + S+WW       ++ V+ L+  G+LE   GGWVM DEA  HY A++DQ+  G ++LE+ 
Sbjct: 218  YLSKWWDIIDIQKKDAVKSLIENGQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLENN 277

Query: 183  FGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRAS 242
             G   +PR  W IDPFGHS   A L  + G       R+ Y  K        +E  WR +
Sbjct: 278  IG--VKPRSGWAIDPFGHSPTMAYLLNRAGLSHMLIQRVHYAVKKHFALHKTLEFFWRQN 335

Query: 243  TSLKPPTADL------FTGVLPNGYNPPRNLC----------------WDVLCVDQPLVE 280
              L   T  L      ++  +P+   P   +C                W V     P   
Sbjct: 336  WDLGSVTDILCHMMPFYSYDIPHTCGPDPKICCQFDFKRLPGGRFGCPWGV----PPETI 391

Query: 281  DPRSPEYNAKELVDYFLNVATAQGRYYRTNHTVMTMGSDFQYENANMW---FKNLDKLIR 337
             P + +  A+ L+D +      + + +RT   +  +G DF+Y     W   FKN  +L  
Sbjct: 392  HPGNVQSRARMLLDQY----RKKSKLFRTKVLLAPLGDDFRYCEYTEWDLQFKNYQQLFD 447

Query: 338  LVNAQQAKGSSVHVLYSTPACYLWELNKANLT--------WSVKHDDFFPYADGPHQFWT 389
             +N+Q      V + + T + +   L+KA+ T        + V   DFF YAD    +W+
Sbjct: 448  YMNSQSK--FKVKIQFGTLSDFFDALDKADETQRDKGQSMFPVLSGDFFTYADRDDHYWS 505

Query: 390  GYFSSRPALKRYERLSYNFLQVCNQLEALVGLAANVGPYGSGDSAPLNEA-------MAV 442
            GYF+SRP  KR +R+  + L+    L       A+        S+ L  A       + +
Sbjct: 506  GYFTSRPFYKRMDRIMESHLRAAEILYYFALRQAHKYKINKFLSSSLYTALTEARRNLGL 565

Query: 443  LQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNALARLRGFKDHFTFCQQ-----LN 497
             QHHDA++GT++  V  DY  +L       E ++ N+ A L   KD  T+        L 
Sbjct: 566  FQHHDAITGTAKDWVVVDYGTRLFHSLMVLEKIIGNS-AFLLILKDKLTYDSYSPDTFLE 624

Query: 498  ISICPLSQ-----------TAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDPNGRTVP 546
            + +   SQ           +A    ++VYNPL +    +V + VS     V   +G+ V 
Sbjct: 625  MDLKQKSQDSLPQKNIIRLSAEPRYLVVYNPLEQDRISLVSVYVSSPTVQVFSASGKPVE 684

Query: 547  SDV-VIFPSSDSQAHPP-ELLFSASLPALGFSTYSV----------AQVPRWKPQARAPQ 594
              V  ++ ++++ +    E+ F A +P LG   Y +          A    +K +     
Sbjct: 685  VQVSAVWDTANTISETAYEISFRAHIPPLGLKVYKILESASSNSHLADYVLYKNKVEDSG 744

Query: 595  PIPRRSW---SPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDN 651
                ++       +T+EN  +   FD  TGL+ ++M         V   F WY  +I  +
Sbjct: 745  IFTIKNMINTEEGITLENSFVLLRFD-QTGLMKQMMTKEDGKHHEVNVQFSWYGTTIKRD 803

Query: 652  ESDQASGAYIFRPN-QQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLY--PGQR 708
            +    SGAY+F P+   KP   +    + +    +  EV   F    +  VRLY   G  
Sbjct: 804  K----SGAYLFLPDGNAKPYVYTTPPFVRVTHGRIYSEV-TCFFDHVTHRVRLYHIQGIE 858

Query: 709  HLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQT 768
               +E S   + +   + +E+  +  + ++++ RFYTD NG +I       +P   L++ 
Sbjct: 859  GQSVEVS-NIVDIRKVYNREIAMKISSDIKSQNRFYTDLNGYQI-------QPRMTLSKL 910

Query: 769  EPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEP 828
             P+  N YP+ T  YI D   +LT+L+ +S G SSL  G +E+++ RRL++DD RG+ + 
Sbjct: 911  -PLQANVYPMTTMAYIQDAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQG 969

Query: 829  LMENGSGA-----WVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGA 883
            + +N   A      +  R  V  +  + + +   LL+    +   ++  P    A    +
Sbjct: 970  IQDNKITANLFRILLEKRSAVNTEEEKKSVSYPSLLSH---ITSSLMNHPVIPMANKFSS 1026

Query: 884  PP---RTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLR 940
            P    + +FS L+  LP  +HL+ L +            Q  VG  +G +  A + L+ +
Sbjct: 1027 PTLELQGEFSPLQSSLPCDIHLVNLRT-----------IQSKVG--NGHSNEAALILHRK 1073

Query: 941  DLFSTFT-------ITRLQETTLVANQLREAASRLKWTTNTGPTPHQTPYQLDPANITLE 993
                 F+        +  Q   LV   L +       T ++    H  P   + + I L 
Sbjct: 1074 GFDCRFSSKGTGLFCSTTQGKILVQKLLNKFIVE-SLTPSSLSLMHSPPGTQNISEINLS 1132

Query: 994  PMEIRTF 1000
            PMEI TF
Sbjct: 1133 PMEISTF 1139


>gi|211971038 tousled-like kinase 1 isoform 3 [Homo sapiens]
          Length = 670

 Score = 34.7 bits (78), Expect = 0.47
 Identities = 16/44 (36%), Positives = 24/44 (54%)

Query: 208 FAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTAD 251
           F +   DGF F  L  Q +WV  Q+ ++E+  +     KPPTA+
Sbjct: 216 FTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTAN 259


>gi|211971036 tousled-like kinase 1 isoform 2 [Homo sapiens]
          Length = 718

 Score = 34.7 bits (78), Expect = 0.47
 Identities = 16/44 (36%), Positives = 24/44 (54%)

Query: 208 FAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTAD 251
           F +   DGF F  L  Q +WV  Q+ ++E+  +     KPPTA+
Sbjct: 264 FTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTAN 307


>gi|33636698 tousled-like kinase 1 isoform 1 [Homo sapiens]
          Length = 766

 Score = 34.7 bits (78), Expect = 0.47
 Identities = 16/44 (36%), Positives = 24/44 (54%)

Query: 208 FAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTAD 251
           F +   DGF F  L  Q +WV  Q+ ++E+  +     KPPTA+
Sbjct: 312 FTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTAN 355


>gi|31652264 RNA binding motif protein 26 [Homo sapiens]
          Length = 980

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 20/73 (27%), Positives = 38/73 (52%), Gaps = 7/73 (9%)

Query: 724 TWGKEVISRFDTPLE-TKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNTRI 782
           +W KE +   D     T+ R  T S  R+++      +P + L++T+P+  NY PV++  
Sbjct: 186 SWSKERLRERDRDRSRTRSRSRTRSRERDLV------KPKYDLDRTDPLENNYTPVSSVP 239

Query: 783 YITDGNMQLTVLT 795
            I+ G+  +  L+
Sbjct: 240 SISSGHYPVPTLS 252


>gi|124430752 kinesin family member 26B [Homo sapiens]
          Length = 2108

 Score = 31.2 bits (69), Expect = 5.2
 Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 2/72 (2%)

Query: 237 QVWRASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYF 296
           +VW    +L+   +++ TG L +G +P   LC D +C  Q  +++         E   +F
Sbjct: 599 EVWGKEENLRDLLSEVATGSLQDGQSPGVYLCEDPICGTQ--LQNQSELRAPTAEKAAFF 656

Query: 297 LNVATAQGRYYR 308
           L+ A A  R ++
Sbjct: 657 LDAAIASRRSHQ 668


>gi|7661880 centaurin beta1 [Homo sapiens]
          Length = 740

 Score = 30.8 bits (68), Expect = 6.7
 Identities = 20/45 (44%), Positives = 23/45 (51%), Gaps = 3/45 (6%)

Query: 877 AAYNLGAPPRTQFSGLRRDLP---PSVHLLTLASWGPEMVLLRLE 918
           A+ NLG     Q SG+ R L      V  LTL SW PE+V L  E
Sbjct: 431 ASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCE 475


>gi|116292178 hypothetical protein LOC414918 [Homo sapiens]
          Length = 585

 Score = 30.8 bits (68), Expect = 6.7
 Identities = 14/27 (51%), Positives = 16/27 (59%)

Query: 12 ARGCLDSAGPWTMSRALRPPLPPLCFF 38
          ARGCL +AGP +  RA R P  P   F
Sbjct: 12 ARGCLGAAGPTSSGRAARTPAAPWARF 38


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score = 30.4 bits (67), Expect = 8.8
 Identities = 15/66 (22%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 112 PTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFAN--GGWVMNDEAATHYGAIV 169
           P  +++ + +     +   +T   Q+ +   +  GR+E     GGWV+ D +  H+G I+
Sbjct: 38  PNSKYVKLNVGGSLHYTTLRTLTGQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTIL 97

Query: 170 DQMTLG 175
           + +  G
Sbjct: 98  NYLRDG 103


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,639,622
Number of Sequences: 37866
Number of extensions: 2009817
Number of successful extensions: 4350
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 4309
Number of HSP's gapped (non-prelim): 17
length of query: 1011
length of database: 18,247,518
effective HSP length: 112
effective length of query: 899
effective length of database: 14,006,526
effective search space: 12591866874
effective search space used: 12591866874
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.