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Search of human proteins with 5174439
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5174439 fibroblast growth factor 8 isoform B precursor [Homo
sapiens]
(215 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5174439 fibroblast growth factor 8 isoform B precursor [Homo ... 437 e-123
gi|15147346 fibroblast growth factor 8 isoform F precursor [Homo... 422 e-118
gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo... 408 e-114
gi|15147348 fibroblast growth factor 8 isoform E precursor [Homo... 405 e-113
gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens] 254 3e-68
gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens] 231 5e-61
gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens] 74 7e-14
gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens] 72 3e-13
gi|4503691 fibroblast growth factor 16 [Homo sapiens] 72 5e-13
gi|9789947 fibroblast growth factor 20 [Homo sapiens] 69 3e-12
gi|153285461 fibroblast growth factor 2 [Homo sapiens] 68 5e-12
gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens] 67 9e-12
gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens] 62 3e-10
gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens] 58 5e-09
gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens] 57 9e-09
gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens] 55 4e-08
gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens] 55 4e-08
gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens] 55 4e-08
gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens] 55 4e-08
gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens] 55 4e-08
gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens] 55 4e-08
gi|222144221 fibroblast growth factor 1 (acidic) isoform 1 propr... 54 1e-07
gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprot... 54 1e-07
gi|222144273 fibroblast growth factor 1 (acidic) isoform 1 propr... 54 1e-07
gi|222144271 fibroblast growth factor 1 (acidic) isoform 1 propr... 54 1e-07
gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo... 53 2e-07
gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens] 49 3e-06
gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens] 49 3e-06
gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens] 49 4e-06
gi|4758362 fibroblast growth factor 11 [Homo sapiens] 48 5e-06
>gi|5174439 fibroblast growth factor 8 isoform B precursor [Homo
sapiens]
Length = 215
Score = 437 bits (1125), Expect = e-123
Identities = 215/215 (100%), Positives = 215/215 (100%)
Query: 1 MGSPRSALSCLLLHLLVLCLQAQVTVQSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSRT 60
MGSPRSALSCLLLHLLVLCLQAQVTVQSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSRT
Sbjct: 1 MGSPRSALSCLLLHLLVLCLQAQVTVQSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSRT 60
Query: 61 SGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKS 120
SGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKS
Sbjct: 61 SGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKS 120
Query: 121 NGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPR 180
NGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPR
Sbjct: 121 NGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPR 180
Query: 181 GHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR 215
GHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
Sbjct: 181 GHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR 215
>gi|15147346 fibroblast growth factor 8 isoform F precursor [Homo
sapiens]
Length = 244
Score = 422 bits (1085), Expect = e-118
Identities = 215/244 (88%), Positives = 215/244 (88%), Gaps = 29/244 (11%)
Query: 1 MGSPRSALSCLLLHLLVLCLQAQ-----------------------------VTVQSSPN 31
MGSPRSALSCLLLHLLVLCLQAQ VTVQSSPN
Sbjct: 1 MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQVTVQSSPN 60
Query: 32 FTQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETD 91
FTQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETD
Sbjct: 61 FTQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETD 120
Query: 92 TFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYM 151
TFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYM
Sbjct: 121 TFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYM 180
Query: 152 AFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWA 211
AFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWA
Sbjct: 181 AFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWA 240
Query: 212 PEPR 215
PEPR
Sbjct: 241 PEPR 244
>gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo
sapiens]
Length = 204
Score = 408 bits (1048), Expect = e-114
Identities = 204/215 (94%), Positives = 204/215 (94%), Gaps = 11/215 (5%)
Query: 1 MGSPRSALSCLLLHLLVLCLQAQVTVQSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSRT 60
MGSPRSALSCLLLHLLVLCLQAQ HVREQSLVTDQLSRRLIRTYQLYSRT
Sbjct: 1 MGSPRSALSCLLLHLLVLCLQAQ-----------HVREQSLVTDQLSRRLIRTYQLYSRT 49
Query: 61 SGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKS 120
SGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKS
Sbjct: 50 SGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKS 109
Query: 121 NGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPR 180
NGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPR
Sbjct: 110 NGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPR 169
Query: 181 GHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR 215
GHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
Sbjct: 170 GHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR 204
>gi|15147348 fibroblast growth factor 8 isoform E precursor [Homo
sapiens]
Length = 233
Score = 405 bits (1041), Expect = e-113
Identities = 206/233 (88%), Positives = 206/233 (88%), Gaps = 18/233 (7%)
Query: 1 MGSPRSALSCLLLHLLVLCLQAQVTVQSSPNF------------------TQHVREQSLV 42
MGSPRSALSCLLLHLLVLCLQAQ P QHVREQSLV
Sbjct: 1 MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQHVREQSLV 60
Query: 43 TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA 102
TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA
Sbjct: 61 TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA 120
Query: 103 ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG 162
ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG
Sbjct: 121 ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG 180
Query: 163 SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR 215
SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
Sbjct: 181 SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR 233
>gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens]
Length = 216
Score = 254 bits (650), Expect = 3e-68
Identities = 131/208 (62%), Positives = 160/208 (76%), Gaps = 9/208 (4%)
Query: 11 LLLHLLVLCLQAQVTVQSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLAN 70
L L LL+LC Q Q SPNF Q+VR+Q +TDQLSRR IR YQLYSRTSGKHVQV
Sbjct: 12 LCLQLLILCCQTQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQV-TG 70
Query: 71 KRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFT 130
+RI+A AEDG+ FAKLIVETDTFGSRVR++GAE+ YICMNK+GKLI K +GK KDCVFT
Sbjct: 71 RRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFT 130
Query: 131 EIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGH----HTTE 186
EIVLENNYTA QNA++EGW+MAFTR+GRPR+ S++RQ+QRE HF+KRL +G + E
Sbjct: 131 EIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQGQLPFPNHAE 190
Query: 187 QSLRFEFLNYPPFTRSLRGSQRTWAPEP 214
+ +FEF+ P R ++RT P+P
Sbjct: 191 KQKQFEFVGSAP----TRRTKRTRRPQP 214
>gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens]
Length = 207
Score = 231 bits (588), Expect = 5e-61
Identities = 110/192 (57%), Positives = 145/192 (75%), Gaps = 2/192 (1%)
Query: 1 MGSPRSALSCLLLHLLVLCLQAQVTV-QSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSR 59
M S SA +CL LH L+LC Q QV V + + +F HV Q+ D +SR+ +R YQLYSR
Sbjct: 1 MYSAPSACTCLCLHFLLLCFQVQVLVAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSR 60
Query: 60 TSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAK 119
TSGKH+QVL +RI+A EDGD +A+L+VETDTFGS+VR++G ET Y+CMN+KGKL+ K
Sbjct: 61 TSGKHIQVLG-RRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGK 119
Query: 120 SNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLP 179
+G K+CVF E VLENNYTAL +AKY GWY+ FT+KGRPRKG KTR++Q++VHFMKR P
Sbjct: 120 PDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYP 179
Query: 180 RGHHTTEQSLRF 191
+G ++ ++
Sbjct: 180 KGQPELQKPFKY 191
>gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]
Length = 208
Score = 74.3 bits (181), Expect = 7e-14
Identities = 46/134 (34%), Positives = 73/134 (54%), Gaps = 9/134 (6%)
Query: 50 LIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYIC 109
++R QLY RT G H+++ N I +D F L + G V +RG ++GLY+
Sbjct: 60 ILRRRQLYCRT-GFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGL-VSIRGVDSGLYLG 117
Query: 110 MNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEG------WYMAFTRKGRPRKGS 163
MN+KG+L S ++CVF E EN Y + Y+ +Y+A + G PR+G+
Sbjct: 118 MNEKGELYG-SEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGT 176
Query: 164 KTRQHQREVHFMKR 177
+T++HQ+ HF+ R
Sbjct: 177 RTKRHQKFTHFLPR 190
>gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]
Length = 208
Score = 72.4 bits (176), Expect = 3e-13
Identities = 44/128 (34%), Positives = 73/128 (57%), Gaps = 4/128 (3%)
Query: 52 RTYQLYSRTS-GKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICM 110
R +LY G H+QVL + RI+ E+ +P++ L + T G V + G + L++ M
Sbjct: 84 RQRRLYCNVGIGFHLQVLPDGRISGTHEE-NPYSLLEISTVERGV-VSLFGVRSALFVAM 141
Query: 111 NKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQR 170
N KG+L A + + ++C F E +L NNY A ++ Y+G Y+A ++ GR ++GSK
Sbjct: 142 NSKGRLYATPSFQ-EECKFRETLLPNNYNAYESDLYQGTYIALSKYGRVKRGSKVSPIMT 200
Query: 171 EVHFMKRL 178
HF+ R+
Sbjct: 201 VTHFLPRI 208
>gi|4503691 fibroblast growth factor 16 [Homo sapiens]
Length = 207
Score = 71.6 bits (174), Expect = 5e-13
Identities = 43/134 (32%), Positives = 72/134 (53%), Gaps = 9/134 (6%)
Query: 50 LIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYIC 109
++R QLY RT G H+++ N ++ D F L + G + +RG ++GLY+
Sbjct: 59 ILRRRQLYCRT-GFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGL-ISIRGVDSGLYLG 116
Query: 110 MNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEG------WYMAFTRKGRPRKGS 163
MN++G+L S ++CVF E EN Y + Y+ +Y+A + G PR+G
Sbjct: 117 MNERGELYG-SKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGY 175
Query: 164 KTRQHQREVHFMKR 177
+T++HQ+ HF+ R
Sbjct: 176 RTKRHQKFTHFLPR 189
>gi|9789947 fibroblast growth factor 20 [Homo sapiens]
Length = 211
Score = 68.9 bits (167), Expect = 3e-12
Identities = 43/134 (32%), Positives = 71/134 (52%), Gaps = 9/134 (6%)
Query: 50 LIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYIC 109
++R QLY RT G H+Q+L + + +D F L + G V +RG ++GLY+
Sbjct: 63 ILRRRQLYCRT-GFHLQILPDGSVQGTRQDHSLFGILEFISVAVGL-VSIRGVDSGLYLG 120
Query: 110 MNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEG------WYMAFTRKGRPRKGS 163
MN KG+L S +C+F E EN Y + Y+ +++A + G PR G+
Sbjct: 121 MNDKGELYG-SEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGA 179
Query: 164 KTRQHQREVHFMKR 177
++++HQ+ HF+ R
Sbjct: 180 RSKRHQKFTHFLPR 193
>gi|153285461 fibroblast growth factor 2 [Homo sapiens]
Length = 288
Score = 68.2 bits (165), Expect = 5e-12
Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Query: 55 QLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKG 114
+LY + G +++ + R++ + E DP KL ++ + G V ++G Y+ M + G
Sbjct: 164 RLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGV-VSIKGVCANRYLAMKEDG 222
Query: 115 KLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHF 174
+L+A S +C F E + NNY ++ KY WY+A R G+ + GSKT Q+ + F
Sbjct: 223 RLLA-SKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILF 281
Query: 175 M 175
+
Sbjct: 282 L 282
>gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]
Length = 194
Score = 67.4 bits (163), Expect = 9e-12
Identities = 40/129 (31%), Positives = 71/129 (55%), Gaps = 7/129 (5%)
Query: 51 IRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICM 110
IR +L+ RT ++++ ++ E + + + + T G V ++G E+ Y+ M
Sbjct: 64 IRVRRLFCRTQW-YLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGI-VAIKGVESEFYLAM 121
Query: 111 NKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE----GWYMAFTRKGRPRKGSKTR 166
NK+GKL AK +DC F E++LEN+Y +AK+ ++A +KG P +G KT+
Sbjct: 122 NKEGKLYAKKE-CNEDCNFKELILENHYNTYASAKWTHNGGEMFVALNQKGIPVRGKKTK 180
Query: 167 QHQREVHFM 175
+ Q+ HF+
Sbjct: 181 KEQKTAHFL 189
>gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]
Length = 206
Score = 62.4 bits (150), Expect = 3e-10
Identities = 43/130 (33%), Positives = 67/130 (51%), Gaps = 8/130 (6%)
Query: 52 RTYQLYSRTS-GKHVQVLANKRIN-AMAEDGDPFAKLI-VETDTFGSRVRVRGAETGLYI 108
R +LY G H+Q L + RI A A+ D +L VE V + G + ++
Sbjct: 82 RLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELSPVERGV----VSIFGVASRFFV 137
Query: 109 CMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQH 168
M+ KGKL S +C F EI+L NNY A ++ KY G ++A ++ G+ +KG++
Sbjct: 138 AMSSKGKLYG-SPFFTDECTFKEILLPNNYNAYESYKYPGMFIALSKNGKTKKGNRVSPT 196
Query: 169 QREVHFMKRL 178
+ HF+ RL
Sbjct: 197 MKVTHFLPRL 206
>gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]
Length = 208
Score = 58.2 bits (139), Expect = 5e-09
Identities = 44/153 (28%), Positives = 74/153 (48%), Gaps = 13/153 (8%)
Query: 28 SSPNFT-QHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKL 86
SSP+ +HVR + + + R + ++ Y +++ N +++ ++ P++ L
Sbjct: 58 SSPSSAGRHVRSYNHLQGDVRWRKLFSFTKY------FLKIEKNGKVSGTKKENCPYSIL 111
Query: 87 IVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYT--ALQNA 144
+ + G V V+ + Y+ MNKKGKL S DC E + EN Y A N
Sbjct: 112 EITSVEIGV-VAVKAINSNYYLAMNKKGKLYG-SKEFNNDCKLKERIEENGYNTYASFNW 169
Query: 145 KYEG--WYMAFTRKGRPRKGSKTRQHQREVHFM 175
++ G Y+A KG PR+G KTR+ HF+
Sbjct: 170 QHNGRQMYVALNGKGAPRRGQKTRRKNTSAHFL 202
>gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]
Length = 239
Score = 57.4 bits (137), Expect = 9e-09
Identities = 48/155 (30%), Positives = 70/155 (45%), Gaps = 24/155 (15%)
Query: 52 RTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVE-TDTFGSRVRVRGAETGLYICM 110
R +LY T H+Q+ + R+N E+ A I+E T V +RG +G Y+ M
Sbjct: 44 RRRKLYCATK-YHLQLHPSGRVNGSLENS---AYSILEITAVEVGIVAIRGLFSGRYLAM 99
Query: 111 NKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEG----------------WYMAFT 154
NK+G+L A S +C F E + E Y + Y WY++
Sbjct: 100 NKRGRLYA-SEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVN 158
Query: 155 RKGRPRKGSKTRQHQREVHFMKRL--PRGHHTTEQ 187
KGRPR+G KTR+ Q+ F+ R+ R H Q
Sbjct: 159 GKGRPRRGFKTRRTQKSSLFLPRVLDHRDHEMVRQ 193
>gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 55.1 bits (131), Expect = 4e-08
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 55 QLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRV-RVRGAETGLYICMNKK 113
+LYSR G H+Q+ A+ I+ ++ + + G RV ++G +T LY+ MN +
Sbjct: 53 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 109
Query: 114 GKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE------GWYMAFTRKGRPRKGSKTRQ 167
G L S +C F E V EN Y + Y GWY+ ++G KG+ ++
Sbjct: 110 GYLYT-SELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 168
Query: 168 HQREVHFMKR 177
++ HF+ +
Sbjct: 169 NKPAAHFLPK 178
>gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 55.1 bits (131), Expect = 4e-08
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 55 QLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRV-RVRGAETGLYICMNKK 113
+LYSR G H+Q+ A+ I+ ++ + + G RV ++G +T LY+ MN +
Sbjct: 53 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 109
Query: 114 GKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE------GWYMAFTRKGRPRKGSKTRQ 167
G L S +C F E V EN Y + Y GWY+ ++G KG+ ++
Sbjct: 110 GYLYT-SELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 168
Query: 168 HQREVHFMKR 177
++ HF+ +
Sbjct: 169 NKPAAHFLPK 178
>gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]
Length = 255
Score = 55.1 bits (131), Expect = 4e-08
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 55 QLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRV-RVRGAETGLYICMNKK 113
+LYSR G H+Q+ A+ I+ ++ + + G RV ++G +T LY+ MN +
Sbjct: 82 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 138
Query: 114 GKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE------GWYMAFTRKGRPRKGSKTRQ 167
G L S +C F E V EN Y + Y GWY+ ++G KG+ ++
Sbjct: 139 GYLYT-SELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 197
Query: 168 HQREVHFMKR 177
++ HF+ +
Sbjct: 198 NKPAAHFLPK 207
>gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]
Length = 199
Score = 55.1 bits (131), Expect = 4e-08
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 55 QLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRV-RVRGAETGLYICMNKK 113
+LYSR G H+Q+ A+ I+ ++ + + G RV ++G +T LY+ MN +
Sbjct: 26 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 82
Query: 114 GKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE------GWYMAFTRKGRPRKGSKTRQ 167
G L S +C F E V EN Y + Y GWY+ ++G KG+ ++
Sbjct: 83 GYLYT-SELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 141
Query: 168 HQREVHFMKR 177
++ HF+ +
Sbjct: 142 NKPAAHFLPK 151
>gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]
Length = 245
Score = 55.1 bits (131), Expect = 4e-08
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 55 QLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRV-RVRGAETGLYICMNKK 113
+LYSR G H+Q+ A+ I+ ++ + + G RV ++G +T LY+ MN +
Sbjct: 72 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 128
Query: 114 GKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE------GWYMAFTRKGRPRKGSKTRQ 167
G L S +C F E V EN Y + Y GWY+ ++G KG+ ++
Sbjct: 129 GYLYT-SELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 187
Query: 168 HQREVHFMKR 177
++ HF+ +
Sbjct: 188 NKPAAHFLPK 197
>gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]
Length = 192
Score = 55.1 bits (131), Expect = 4e-08
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 55 QLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRV-RVRGAETGLYICMNKK 113
+LYSR G H+Q+ A+ I+ ++ + + G RV ++G +T LY+ MN +
Sbjct: 19 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 75
Query: 114 GKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE------GWYMAFTRKGRPRKGSKTRQ 167
G L S +C F E V EN Y + Y GWY+ ++G KG+ ++
Sbjct: 76 GYLYT-SELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 134
Query: 168 HQREVHFMKR 177
++ HF+ +
Sbjct: 135 NKPAAHFLPK 144
>gi|222144221 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 53.5 bits (127), Expect = 1e-07
Identities = 29/122 (23%), Positives = 62/122 (50%), Gaps = 4/122 (3%)
Query: 56 LYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGK 115
LY G +++L + ++ + D +L + ++ G V ++ ETG Y+ M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGE-VYIKSTETGQYLAMDTDG- 86
Query: 116 LIAKSNGKGKDCVFTEIVLENNYTALQNAKY--EGWYMAFTRKGRPRKGSKTRQHQREVH 173
L+ S ++C+F E + EN+Y + K+ + W++ + G ++G +T Q+ +
Sbjct: 87 LLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 174 FM 175
F+
Sbjct: 147 FL 148
>gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprotein
[Homo sapiens]
Length = 155
Score = 53.5 bits (127), Expect = 1e-07
Identities = 29/122 (23%), Positives = 62/122 (50%), Gaps = 4/122 (3%)
Query: 56 LYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGK 115
LY G +++L + ++ + D +L + ++ G V ++ ETG Y+ M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGE-VYIKSTETGQYLAMDTDG- 86
Query: 116 LIAKSNGKGKDCVFTEIVLENNYTALQNAKY--EGWYMAFTRKGRPRKGSKTRQHQREVH 173
L+ S ++C+F E + EN+Y + K+ + W++ + G ++G +T Q+ +
Sbjct: 87 LLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 174 FM 175
F+
Sbjct: 147 FL 148
>gi|222144273 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 53.5 bits (127), Expect = 1e-07
Identities = 29/122 (23%), Positives = 62/122 (50%), Gaps = 4/122 (3%)
Query: 56 LYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGK 115
LY G +++L + ++ + D +L + ++ G V ++ ETG Y+ M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGE-VYIKSTETGQYLAMDTDG- 86
Query: 116 LIAKSNGKGKDCVFTEIVLENNYTALQNAKY--EGWYMAFTRKGRPRKGSKTRQHQREVH 173
L+ S ++C+F E + EN+Y + K+ + W++ + G ++G +T Q+ +
Sbjct: 87 LLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 174 FM 175
F+
Sbjct: 147 FL 148
>gi|222144271 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 53.5 bits (127), Expect = 1e-07
Identities = 29/122 (23%), Positives = 62/122 (50%), Gaps = 4/122 (3%)
Query: 56 LYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGK 115
LY G +++L + ++ + D +L + ++ G V ++ ETG Y+ M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGE-VYIKSTETGQYLAMDTDG- 86
Query: 116 LIAKSNGKGKDCVFTEIVLENNYTALQNAKY--EGWYMAFTRKGRPRKGSKTRQHQREVH 173
L+ S ++C+F E + EN+Y + K+ + W++ + G ++G +T Q+ +
Sbjct: 87 LLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 174 FM 175
F+
Sbjct: 147 FL 148
>gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo
sapiens]
Length = 268
Score = 52.8 bits (125), Expect = 2e-07
Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 21/152 (13%)
Query: 52 RTYQLYSRTS-GKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSR---VRVRGAETGLY 107
RT LY R G H+Q+ + ++N E A ++ + F V +RG + +
Sbjct: 87 RTGSLYCRVGIGFHLQIYPDGKVNGSHE-----ANMLSVLEIFAVSQGIVGIRGVFSNKF 141
Query: 108 ICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKY------EGWYMAFTRKGRPRK 161
+ M+KKGKL A + DC F E EN+Y +A + WY+A ++G+ ++
Sbjct: 142 LAMSKKGKLHASAKFT-DDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGKAKR 200
Query: 162 GSKTRQHQREV--HFMKRLPRGHHTTEQSLRF 191
G R + + HF LPR + + L F
Sbjct: 201 GCSPRVKPQHISTHF---LPRFKQSEQPELSF 229
>gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]
Length = 252
Score = 48.9 bits (115), Expect = 3e-06
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 97 VRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKY------EGWY 150
V ++G +TGLYI MN +G L S +C F E V EN Y + Y W+
Sbjct: 119 VAIQGVKTGLYIAMNGEGYLY-PSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWF 177
Query: 151 MAFTRKGRPRKGSKTRQHQREVHFMKR 177
+ ++G+ KG++ ++ + HF+ +
Sbjct: 178 LGLNKEGQAMKGNRVKKTKPAAHFLPK 204
>gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens]
Length = 247
Score = 48.9 bits (115), Expect = 3e-06
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 97 VRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKY------EGWY 150
V ++G +TGLYI MN +G L S +C F E V EN Y + Y W+
Sbjct: 114 VAIQGVKTGLYIAMNGEGYLY-PSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWF 172
Query: 151 MAFTRKGRPRKGSKTRQHQREVHFMKR 177
+ ++G+ KG++ ++ + HF+ +
Sbjct: 173 LGLNKEGQAMKGNRVKKTKPAAHFLPK 199
>gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens]
Length = 170
Score = 48.5 bits (114), Expect = 4e-06
Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 5/83 (6%)
Query: 97 VRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKY----EGWYMA 152
V ++ +G Y+ MN++G+L S DC F E + EN + + ++ + ++A
Sbjct: 84 VVIKAVSSGFYVAMNRRGRLYG-SRLYTVDCRFRERIEENGHNTYASQRWRRRGQPMFLA 142
Query: 153 FTRKGRPRKGSKTRQHQREVHFM 175
R+G PR G +TR++ HF+
Sbjct: 143 LDRRGGPRPGGRTRRYHLSAHFL 165
>gi|4758362 fibroblast growth factor 11 [Homo sapiens]
Length = 225
Score = 48.1 bits (113), Expect = 5e-06
Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 7/88 (7%)
Query: 97 VRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE------GWY 150
V ++ A+ G Y+ MN +G L + + +C F E V EN Y +A Y WY
Sbjct: 114 VTIQSAKLGHYMAMNAEGLLYSSPHFTA-ECRFKECVFENYYVLYASALYRQRRSGRAWY 172
Query: 151 MAFTRKGRPRKGSKTRQHQREVHFMKRL 178
+ ++G+ KG++ ++ + HF+ +L
Sbjct: 173 LGLDKEGQVMKGNRVKKTKAAAHFLPKL 200
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.133 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,105,056
Number of Sequences: 37866
Number of extensions: 326661
Number of successful extensions: 742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 685
Number of HSP's gapped (non-prelim): 42
length of query: 215
length of database: 18,247,518
effective HSP length: 98
effective length of query: 117
effective length of database: 14,536,650
effective search space: 1700788050
effective search space used: 1700788050
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.