Guide to the Human Genome
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Search of human proteins with 50428938

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50428938 arsA arsenite transporter, ATP-binding, homolog 1
[Homo sapiens]
         (348 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50428938 arsA arsenite transporter, ATP-binding, homolog 1 [H...   698   0.0  
gi|6912540 nucleotide binding protein 2 (MinD homolog, E. coli) ...    31   1.4  
gi|4506467 radixin [Homo sapiens]                                      30   4.2  
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac...    29   5.5  
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]           29   5.5  
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]      29   7.1  
gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]          28   9.3  
gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]          28   9.3  
gi|193083180 cytochrome P450 family 4 subfamily F polypeptide 11...    28   9.3  
gi|193083178 cytochrome P450 family 4 subfamily F polypeptide 11...    28   9.3  
gi|149773468 RAD51 associated protein 2 [Homo sapiens]                 28   9.3  

>gi|50428938 arsA arsenite transporter, ATP-binding, homolog 1 [Homo
           sapiens]
          Length = 348

 Score =  698 bits (1801), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MAAGVAGWGVEAEEFEDAPDVEPLEPTLSNIIEQRSLKWIFVGGKGGVGKTTCSCSLAVQ 60
           MAAGVAGWGVEAEEFEDAPDVEPLEPTLSNIIEQRSLKWIFVGGKGGVGKTTCSCSLAVQ
Sbjct: 1   MAAGVAGWGVEAEEFEDAPDVEPLEPTLSNIIEQRSLKWIFVGGKGGVGKTTCSCSLAVQ 60

Query: 61  LSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFE 120
           LSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFE
Sbjct: 61  LSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFE 120

Query: 121 EDNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTGHTLRLLNFP 180
           EDNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTGHTLRLLNFP
Sbjct: 121 EDNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTGHTLRLLNFP 180

Query: 181 TIVERGLGRLMQIKNQISPFISQMCNMLGLGDMNADQLASKLEETLPVIRSVSEQFKDPE 240
           TIVERGLGRLMQIKNQISPFISQMCNMLGLGDMNADQLASKLEETLPVIRSVSEQFKDPE
Sbjct: 181 TIVERGLGRLMQIKNQISPFISQMCNMLGLGDMNADQLASKLEETLPVIRSVSEQFKDPE 240

Query: 241 QTTFICVCIAEFLSLYETERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQA 300
           QTTFICVCIAEFLSLYETERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQA
Sbjct: 241 QTTFICVCIAEFLSLYETERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQA 300

Query: 301 KYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSALLLEPYKPPSAQ 348
           KYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSALLLEPYKPPSAQ
Sbjct: 301 KYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSALLLEPYKPPSAQ 348


>gi|6912540 nucleotide binding protein 2 (MinD homolog, E. coli)
          [Homo sapiens]
          Length = 271

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 15/35 (42%), Positives = 21/35 (60%)

Query: 40 IFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTD 74
          + + GKGGVGK+T S  LA+ L    + V I+  D
Sbjct: 18 LVLSGKGGVGKSTISTELALALRHAGKKVGILDVD 52


>gi|4506467 radixin [Homo sapiens]
          Length = 583

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 4/78 (5%)

Query: 250 AEFLSLYETERLIQELAKCK--IDTHNIIVNQLVFPDPEKPCKMCEARHKIQAKYLDQME 307
           A+F     +E LIQE+ +    +     I+N  ++  PE    +  A + +QAKY D  +
Sbjct: 82  AKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLL--ASYAVQAKYGDYNK 139

Query: 308 DLYEDFHIVKLPLLPHEV 325
           ++++  ++    LLP  V
Sbjct: 140 EIHKPGYLANDRLLPQRV 157


>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform b [Homo sapiens]
          Length = 7968

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 6/41 (14%)

Query: 7    GWGVEAEEFEDAPDVEPLEPTLSNIIEQRSLKWIFVGGKGG 47
            GW  EAE+  D+       PTL    EQ +++   +GG+GG
Sbjct: 7150 GWTQEAEDLSDST------PTLQRPQEQATMRKFSLGGRGG 7184


>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
          Length = 5120

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 9/81 (11%)

Query: 64   GRESVLIISTD---PAHNISDAFDQKF---SKVPTKVKGYDNLFAMEIDPSLGVAELPDE 117
            G E+ +I+      P    S  FDQ++    K+  K+KGYD+   + + P     +LP E
Sbjct: 1841 GDEAEVIVKNPCNFPIEFYSLEFDQQYLIEEKILRKLKGYDSYNTLLLPPRNPGEKLPPE 1900

Query: 118  FFEEDNMLSMGKKMMQEAMSA 138
             +E    +   KK  +E M A
Sbjct: 1901 LYEYFKEI---KKSKEEQMRA 1918


>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
          Length = 4158

 Score = 28.9 bits (63), Expect = 7.1
 Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 14/91 (15%)

Query: 54   SCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTK---VKGYDNLFAMEIDPSLG 110
            +C LAV      E ++   TDP   I D F    S +P+    V    N   +  +P  G
Sbjct: 3600 NCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKG 3659

Query: 111  V--------AELPDEFFEEDNMLSMGKKMMQ 133
            +         E+   FFEE+    +GKK  Q
Sbjct: 3660 LRANIRRAFTEMTPSFFEEN---ILGKKWRQ 3687


>gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]
          Length = 1368

 Score = 28.5 bits (62), Expect = 9.3
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 16/78 (20%)

Query: 218  LASKLEETLPVIRSVSEQ------FKDPEQTTFICVCIAEFLSLYETERLIQEL------ 265
            L  +  E +P++R +S Q      F   + TT     ++EF +L  TER   ++      
Sbjct: 1077 LQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPS 1136

Query: 266  ----AKCKIDTHNIIVNQ 279
                 K  IDTHN ++ Q
Sbjct: 1137 SPSPVKFLIDTHNRLLLQ 1154


>gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]
          Length = 1445

 Score = 28.5 bits (62), Expect = 9.3
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 16/78 (20%)

Query: 218  LASKLEETLPVIRSVSEQ------FKDPEQTTFICVCIAEFLSLYETERLIQEL------ 265
            L  +  E +P++R +S Q      F   + TT     ++EF +L  TER   ++      
Sbjct: 1154 LQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPS 1213

Query: 266  ----AKCKIDTHNIIVNQ 279
                 K  IDTHN ++ Q
Sbjct: 1214 SPSPVKFLIDTHNRLLLQ 1231


>gi|193083180 cytochrome P450 family 4 subfamily F polypeptide 11
           [Homo sapiens]
          Length = 524

 Score = 28.5 bits (62), Expect = 9.3
 Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 16/87 (18%)

Query: 216 DQLASKLEETLPVIRSVSEQFKDPEQTTFICVCIAEFLSLYETE---------------- 259
           +Q   +++E L     +  ++ D  Q  F+ +CI E L L+                   
Sbjct: 352 EQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDG 411

Query: 260 RLIQELAKCKIDTHNIIVNQLVFPDPE 286
           R+I +   C I+   I  N  V+PDPE
Sbjct: 412 RVIPKGIVCLINIIGIHYNPTVWPDPE 438


>gi|193083178 cytochrome P450 family 4 subfamily F polypeptide 11
           [Homo sapiens]
          Length = 524

 Score = 28.5 bits (62), Expect = 9.3
 Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 16/87 (18%)

Query: 216 DQLASKLEETLPVIRSVSEQFKDPEQTTFICVCIAEFLSLYETE---------------- 259
           +Q   +++E L     +  ++ D  Q  F+ +CI E L L+                   
Sbjct: 352 EQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDG 411

Query: 260 RLIQELAKCKIDTHNIIVNQLVFPDPE 286
           R+I +   C I+   I  N  V+PDPE
Sbjct: 412 RVIPKGIVCLINIIGIHYNPTVWPDPE 438


>gi|149773468 RAD51 associated protein 2 [Homo sapiens]
          Length = 1159

 Score = 28.5 bits (62), Expect = 9.3
 Identities = 31/121 (25%), Positives = 53/121 (43%), Gaps = 13/121 (10%)

Query: 91   PTKVKGYDNLFAMEIDPSLGVAELPDEF-----FEEDNMLSMGKKMMQEAMSAFPGIDEA 145
            P   K + +LF  +  P+ G  E+P+E       EE+ + S  +K  +  +   P     
Sbjct: 1038 PNMGKSHQSLFKWKTVPNNGEQEVPNESCYPSRSEEELLYSTSEKDCETPLPKRPAFLPD 1097

Query: 146  MSYAEVMRLVK-GMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQM 204
                E   L++ G +F   +    P    L+  + P  +  GL R  +IK Q+ P++ QM
Sbjct: 1098 ECKEEFNYLLRGGSHFPHGISRVRP----LKTCSRP--IRIGLSRKARIK-QLHPYLKQM 1150

Query: 205  C 205
            C
Sbjct: 1151 C 1151


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,786,443
Number of Sequences: 37866
Number of extensions: 529782
Number of successful extensions: 1292
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1290
Number of HSP's gapped (non-prelim): 11
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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