Guide to the Human Genome
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Search of human proteins with 50363237

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens]
         (223 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens]          477   e-135
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]           449   e-126
gi|71834853 prostate specific antigen isoform 3 preproprotein [H...   332   1e-91
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho...   332   1e-91
gi|4504875 kallikrein 1 preproprotein [Homo sapiens]                  290   5e-79
gi|71834855 prostate specific antigen isoform 4 preproprotein [H...   253   9e-68
gi|71834857 prostate specific antigen isoform 5 preproprotein [H...   237   7e-63
gi|11496281 kallikrein 13 precursor [Homo sapiens]                    166   1e-41
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]     162   2e-40
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]          162   2e-40
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]       162   2e-40
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote...   151   4e-37
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei...   151   4e-37
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]                     141   4e-34
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]        141   4e-34
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]             139   1e-33
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]        138   3e-33
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]           137   7e-33
gi|91823048 kallikrein 14 preproprotein [Homo sapiens]                137   7e-33
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]       136   1e-32
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s...   135   3e-32
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]           134   5e-32
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot...   134   6e-32
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H...   131   4e-31
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho...   131   4e-31
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ...   131   4e-31
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ...   131   4e-31
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa...   131   4e-31
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]                     126   1e-29
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]                    126   1e-29

>gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens]
          Length = 223

 Score =  477 bits (1227), Expect = e-135
 Identities = 223/223 (100%), Positives = 223/223 (100%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV
Sbjct: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
           LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD
Sbjct: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120

Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
           LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS
Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180

Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGVSHPYSQHLEGKG 223
           NDMCARAYSEKVTEFMLCAGLWTGGKDTCGVSHPYSQHLEGKG
Sbjct: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGVSHPYSQHLEGKG 223


>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
          Length = 261

 Score =  449 bits (1154), Expect = e-126
 Identities = 210/210 (100%), Positives = 210/210 (100%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV
Sbjct: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
           LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD
Sbjct: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120

Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
           LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS
Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180

Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCG 210
           NDMCARAYSEKVTEFMLCAGLWTGGKDTCG
Sbjct: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCG 210


>gi|71834853 prostate specific antigen isoform 3 preproprotein [Homo
           sapiens]
          Length = 238

 Score =  332 bits (852), Expect = 1e-91
 Identities = 155/209 (74%), Positives = 176/209 (84%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MW  V+ + LSV   GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV
Sbjct: 1   MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
           LTAAHC++  S + LGRH+LF PEDTGQ   VSHSFPHPLY+MSLLK++ LRP +DSSHD
Sbjct: 61  LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120

Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
           LMLLRLSEPA++TD VKV+ LPTQEPALGTTCYASGWGSIEPEEFL P+ LQCV LH++S
Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180

Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTC 209
           ND+CA+ + +KVT+FMLCAG WTGGK TC
Sbjct: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTC 209


>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
           sapiens]
          Length = 261

 Score =  332 bits (852), Expect = 1e-91
 Identities = 155/209 (74%), Positives = 176/209 (84%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MW  V+ + LSV   GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV
Sbjct: 1   MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
           LTAAHC++  S + LGRH+LF PEDTGQ   VSHSFPHPLY+MSLLK++ LRP +DSSHD
Sbjct: 61  LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120

Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
           LMLLRLSEPA++TD VKV+ LPTQEPALGTTCYASGWGSIEPEEFL P+ LQCV LH++S
Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180

Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTC 209
           ND+CA+ + +KVT+FMLCAG WTGGK TC
Sbjct: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTC 209


>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
          Length = 262

 Score =  290 bits (743), Expect = 5e-79
 Identities = 139/210 (66%), Positives = 163/210 (77%), Gaps = 1/210 (0%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MW LVL +ALS+G TGA P IQSRIVGGWECE+HSQPWQ A+Y      CGG+LVH QWV
Sbjct: 1   MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
           LTAAHC+  N Q+WLGRHNLF+ E+T Q V VS SFPHP +NMSLL++ + + DED SHD
Sbjct: 61  LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120

Query: 121 LMLLRLSEPA-KITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLL 179
           LMLLRL+EPA  ITD VKV+ LPT+EP +G+TC ASGWGSIEPE F  P  LQCV L +L
Sbjct: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180

Query: 180 SNDMCARAYSEKVTEFMLCAGLWTGGKDTC 209
            ND C +A+ +KVT+FMLC G   GGKDTC
Sbjct: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTC 210


>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
           sapiens]
          Length = 218

 Score =  253 bits (646), Expect = 9e-68
 Identities = 126/209 (60%), Positives = 142/209 (67%), Gaps = 43/209 (20%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MW  V+ + LSV   GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV
Sbjct: 1   MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
           LTAAHC++K                                           P +DSSHD
Sbjct: 61  LTAAHCIRK-------------------------------------------PGDDSSHD 77

Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
           LMLLRLSEPA++TD VKV+ LPTQEPALGTTCYASGWGSIEPEEFL P+ LQCV LH++S
Sbjct: 78  LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 137

Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTC 209
           ND+CA+ + +KVT+FMLCAG WTGGK TC
Sbjct: 138 NDVCAQVHPQKVTKFMLCAGRWTGGKSTC 166


>gi|71834857 prostate specific antigen isoform 5 preproprotein [Homo
           sapiens]
          Length = 220

 Score =  237 bits (604), Expect = 7e-63
 Identities = 119/209 (56%), Positives = 137/209 (65%), Gaps = 41/209 (19%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MW  V+ + LSV   GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV
Sbjct: 1   MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
           LTAAHC++  S + LGRH+LF PEDTGQ   VSHSFPHPLY+MSLLK++ LRP +DS   
Sbjct: 61  LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS--- 117

Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
                                                 SIEPEEFL P+ LQCV LH++S
Sbjct: 118 --------------------------------------SIEPEEFLTPKKLQCVDLHVIS 139

Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTC 209
           ND+CA+ + +KVT+FMLCAG WTGGK TC
Sbjct: 140 NDVCAQVHPQKVTKFMLCAGRWTGGKSTC 168


>gi|11496281 kallikrein 13 precursor [Homo sapiens]
          Length = 277

 Score =  166 bits (420), Expect = 1e-41
 Identities = 94/223 (42%), Positives = 124/223 (55%), Gaps = 23/223 (10%)

Query: 1   MWDLVLSIA-LSVGCTGAVPLIQSRIV----------GGWECEKHSQPWQVAVYSHGWAH 49
           MW L L IA L++  +G V    S+++          GG+ C  HSQPWQ A+   G   
Sbjct: 1   MWPLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLL 60

Query: 50  CGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMS--LLK 107
           CGGVLVHP+WVLTAAHCLK+  +V+LG+H L   E   Q   V HS PHP Y  S   L 
Sbjct: 61  CGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLN 120

Query: 108 HQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP-TQEPALGTTCYASGWGSIEPEEFL 166
           H          HD+MLL L  P ++T  ++ L L        GTTC  SGWG+    +  
Sbjct: 121 H---------DHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVN 171

Query: 167 RPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTC 209
            P++LQC ++ L S++ C + Y  K+T+ MLCAG   GGKD+C
Sbjct: 172 YPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSC 214


>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
          Length = 250

 Score =  162 bits (411), Expect = 2e-40
 Identities = 79/205 (38%), Positives = 122/205 (59%), Gaps = 11/205 (5%)

Query: 5   VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAA 64
           ++ +AL+ G  G     ++RI+ G+EC+ HSQPWQ A++      CG  L+ P+W+LTAA
Sbjct: 6   LILLALATGLVGG----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61

Query: 65  HCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124
           HCLK    V LG+HNL + E   Q    + SFPHP +N SL       P++D  +D+ML+
Sbjct: 62  HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 114

Query: 125 RLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184
           +++ P  IT  V+ L L ++    GT+C  SGWGS    +   P +L+C ++ ++ +  C
Sbjct: 115 KMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 174

Query: 185 ARAYSEKVTEFMLCAGLWTGGKDTC 209
             AY   +T+ M+CA +  GGKD+C
Sbjct: 175 ENAYPGNITDTMVCASVQEGGKDSC 199


>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
          Length = 282

 Score =  162 bits (411), Expect = 2e-40
 Identities = 79/205 (38%), Positives = 122/205 (59%), Gaps = 11/205 (5%)

Query: 5   VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAA 64
           ++ +AL+ G  G     ++RI+ G+EC+ HSQPWQ A++      CG  L+ P+W+LTAA
Sbjct: 38  LILLALATGLVGG----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93

Query: 65  HCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124
           HCLK    V LG+HNL + E   Q    + SFPHP +N SL       P++D  +D+ML+
Sbjct: 94  HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 146

Query: 125 RLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184
           +++ P  IT  V+ L L ++    GT+C  SGWGS    +   P +L+C ++ ++ +  C
Sbjct: 147 KMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 206

Query: 185 ARAYSEKVTEFMLCAGLWTGGKDTC 209
             AY   +T+ M+CA +  GGKD+C
Sbjct: 207 ENAYPGNITDTMVCASVQEGGKDSC 231


>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
          Length = 250

 Score =  162 bits (411), Expect = 2e-40
 Identities = 79/205 (38%), Positives = 122/205 (59%), Gaps = 11/205 (5%)

Query: 5   VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAA 64
           ++ +AL+ G  G     ++RI+ G+EC+ HSQPWQ A++      CG  L+ P+W+LTAA
Sbjct: 6   LILLALATGLVGG----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61

Query: 65  HCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124
           HCLK    V LG+HNL + E   Q    + SFPHP +N SL       P++D  +D+ML+
Sbjct: 62  HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 114

Query: 125 RLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184
           +++ P  IT  V+ L L ++    GT+C  SGWGS    +   P +L+C ++ ++ +  C
Sbjct: 115 KMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 174

Query: 185 ARAYSEKVTEFMLCAGLWTGGKDTC 209
             AY   +T+ M+CA +  GGKD+C
Sbjct: 175 ENAYPGNITDTMVCASVQEGGKDSC 199


>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
           [Homo sapiens]
          Length = 244

 Score =  151 bits (382), Expect = 4e-37
 Identities = 77/188 (40%), Positives = 114/188 (60%), Gaps = 13/188 (6%)

Query: 22  QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
           Q+++V G  C+K S P+Q A+Y+ G   CGGVL+HP WVLTAAHC K N QV+LG+HNL 
Sbjct: 19  QNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLR 78

Query: 82  EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141
           + E + ++  V  +  HP Y+ +               D+MLLRL+ PAK++++++ L L
Sbjct: 79  QRESSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAKLSELIQPLPL 127

Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201
                A  T+C+  GWG     +F  P ++QC  +HL+S + C  AY  ++T+ MLCAG 
Sbjct: 128 ERDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGD 185

Query: 202 WTGGKDTC 209
              GKD+C
Sbjct: 186 EKYGKDSC 193


>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
           [Homo sapiens]
          Length = 244

 Score =  151 bits (382), Expect = 4e-37
 Identities = 77/188 (40%), Positives = 114/188 (60%), Gaps = 13/188 (6%)

Query: 22  QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
           Q+++V G  C+K S P+Q A+Y+ G   CGGVL+HP WVLTAAHC K N QV+LG+HNL 
Sbjct: 19  QNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLR 78

Query: 82  EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141
           + E + ++  V  +  HP Y+ +               D+MLLRL+ PAK++++++ L L
Sbjct: 79  QRESSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAKLSELIQPLPL 127

Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201
                A  T+C+  GWG     +F  P ++QC  +HL+S + C  AY  ++T+ MLCAG 
Sbjct: 128 ERDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGD 185

Query: 202 WTGGKDTC 209
              GKD+C
Sbjct: 186 EKYGKDSC 193


>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
          Length = 305

 Score =  141 bits (356), Expect = 4e-34
 Identities = 75/188 (39%), Positives = 101/188 (53%), Gaps = 9/188 (4%)

Query: 22  QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
           + +++GG EC+ HSQPWQ A++      CGGVLV   WVLTAAHC K    V LG H+L 
Sbjct: 75  EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134

Query: 82  EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141
             +   Q +PV  S PHP YN S +        ED +HDLMLL+L + A +   VK + L
Sbjct: 135 NKDGPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISL 186

Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201
                  G  C  SGWG++       P +L C  + +     C  AY  ++T+ M+CAG 
Sbjct: 187 ADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS 246

Query: 202 WTGGKDTC 209
            + G DTC
Sbjct: 247 -SKGADTC 253


>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
          Length = 260

 Score =  141 bits (356), Expect = 4e-34
 Identities = 75/188 (39%), Positives = 101/188 (53%), Gaps = 9/188 (4%)

Query: 22  QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
           + +++GG EC+ HSQPWQ A++      CGGVLV   WVLTAAHC K    V LG H+L 
Sbjct: 30  EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 89

Query: 82  EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141
             +   Q +PV  S PHP YN S +        ED +HDLMLL+L + A +   VK + L
Sbjct: 90  NKDGPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISL 141

Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201
                  G  C  SGWG++       P +L C  + +     C  AY  ++T+ M+CAG 
Sbjct: 142 ADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS 201

Query: 202 WTGGKDTC 209
            + G DTC
Sbjct: 202 -SKGADTC 208


>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
          Length = 250

 Score =  139 bits (351), Expect = 1e-33
 Identities = 70/187 (37%), Positives = 105/187 (56%), Gaps = 7/187 (3%)

Query: 23  SRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82
           +R +G  EC  +SQPWQ  ++      CG  L+  +W+LTAAHC K    V LG H+L++
Sbjct: 21  TRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEHHLWK 80

Query: 83  PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142
            E   Q   V+  FPHP +N  L  +       D + D+ML+RL   A+++  V+ L L 
Sbjct: 81  WEGPEQLFRVTDFFPHPGFNKDLSAN-------DHNDDIMLIRLPRQARLSPAVQPLNLS 133

Query: 143 TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLW 202
               + G  C  SGWG++   + L P +LQC ++ +L N +C  AY   +++ MLCAGLW
Sbjct: 134 QTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLW 193

Query: 203 TGGKDTC 209
            GG+ +C
Sbjct: 194 EGGRGSC 200


>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
          Length = 247

 Score =  138 bits (348), Expect = 3e-33
 Identities = 79/199 (39%), Positives = 105/199 (52%), Gaps = 13/199 (6%)

Query: 12  VGCTGAVPLIQS-RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKN 70
           VG   AVP     +IVGG+ CE++S P+QV++ S G   CGG L+  QWV++AAHC K  
Sbjct: 10  VGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTR 68

Query: 71  SQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPA 130
            QV LG HN+   E   Q +  +    HP YN   L            +D+ML++LS PA
Sbjct: 69  IQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTL-----------DNDIMLIKLSSPA 117

Query: 131 KITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190
            I   V  + LPT  PA GT C  SGWG+        P  L+C+   +L+   C  +Y  
Sbjct: 118 VINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPG 177

Query: 191 KVTEFMLCAGLWTGGKDTC 209
           K+T  M C G   GGKD+C
Sbjct: 178 KITNSMFCVGFLEGGKDSC 196


>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
          Length = 247

 Score =  137 bits (345), Expect = 7e-33
 Identities = 73/186 (39%), Positives = 101/186 (54%), Gaps = 12/186 (6%)

Query: 24  RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83
           +IVGG+ CE++S P+QV++ S G+  CGG L++ QWV++A HC K   QV LG HN+   
Sbjct: 23  KIVGGYNCEENSVPYQVSLNS-GYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVL 81

Query: 84  EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143
           E   Q +  +    HP Y+   L           ++D+ML++LS  A I   V  + LPT
Sbjct: 82  EGNEQFINAAKIIRHPQYDRKTL-----------NNDIMLIKLSSRAVINARVSTISLPT 130

Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203
             PA GT C  SGWG+        P  LQC+   +LS   C  +Y  K+T  M C G   
Sbjct: 131 APPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLE 190

Query: 204 GGKDTC 209
           GGKD+C
Sbjct: 191 GGKDSC 196


>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
          Length = 267

 Score =  137 bits (345), Expect = 7e-33
 Identities = 74/190 (38%), Positives = 108/190 (56%), Gaps = 13/190 (6%)

Query: 22  QSRIVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCLKKNSQVWLGRHN 79
           +++I+GG  C + SQPWQ A+ +       CGG L+  QWV+TAAHC +   QV LG+HN
Sbjct: 38  ENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHN 97

Query: 80  LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139
           L   E T Q + V     HP YN                +DLMLL+L +PA+I   V+ +
Sbjct: 98  LRRWEATQQVLRVVRQVTHPNYN-----------SRTHDNDLMLLQLQQPARIGRAVRPI 146

Query: 140 GLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCA 199
            +     + GT+C  SGWG+I       P SLQCV++++  +++C +AY   +T  M+CA
Sbjct: 147 EVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCA 206

Query: 200 GLWTGGKDTC 209
           G+  GGKD+C
Sbjct: 207 GVPQGGKDSC 216


>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
          Length = 304

 Score =  136 bits (343), Expect = 1e-32
 Identities = 78/196 (39%), Positives = 104/196 (53%), Gaps = 13/196 (6%)

Query: 15  TGAVPLIQS-RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQV 73
           T AVP     +IVGG+ CE++S P+QV++ S G   CGG L+  QWV++AAHC K   QV
Sbjct: 70  TVAVPFDDDDKIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTRIQV 128

Query: 74  WLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKIT 133
            LG HN+   E   Q +  +    HP YN   L            +D+ML++LS PA I 
Sbjct: 129 RLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTL-----------DNDIMLIKLSSPAVIN 177

Query: 134 DVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVT 193
             V  + LPT  PA GT C  SGWG+        P  L+C+   +L+   C  +Y  K+T
Sbjct: 178 ARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKIT 237

Query: 194 EFMLCAGLWTGGKDTC 209
             M C G   GGKD+C
Sbjct: 238 NSMFCVGFLEGGKDSC 253


>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
           sapiens]
          Length = 254

 Score =  135 bits (340), Expect = 3e-32
 Identities = 71/188 (37%), Positives = 103/188 (54%), Gaps = 14/188 (7%)

Query: 23  SRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82
           S+I+ G +C  HSQPWQ A+       C GVLVHPQWVL+AAHC + +  + LG H+L  
Sbjct: 29  SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88

Query: 83  PEDTG-QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141
            ++ G Q V  S S  HP YN  LL           ++DLML++L E    +D ++ + +
Sbjct: 89  DQEPGSQMVEASLSVRHPEYNRPLL-----------ANDLMLIKLDESVSESDTIRSISI 137

Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201
            +Q P  G +C  SGWG +       P  LQCV++ ++S ++C++ Y       M CAG 
Sbjct: 138 ASQCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGG 195

Query: 202 WTGGKDTC 209
               KD+C
Sbjct: 196 GHDQKDSC 203


>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
          Length = 247

 Score =  134 bits (338), Expect = 5e-32
 Identities = 73/186 (39%), Positives = 99/186 (53%), Gaps = 12/186 (6%)

Query: 24  RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83
           +IVGG+ CE++S P+QV++ S G+  CGG L+  QWV++A HC K   QV LG HN+   
Sbjct: 23  KIVGGYICEENSVPYQVSLNS-GYHFCGGSLISEQWVVSAGHCYKSRIQVRLGEHNIEVL 81

Query: 84  EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143
           E   Q +  +    HP YN   L            +D++L++LS PA I   V  + LPT
Sbjct: 82  EGNEQFINAAKIIRHPKYNSRTL-----------DNDILLIKLSSPAVINSRVSAISLPT 130

Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203
             PA GT    SGWG+        P  LQC+   +LS   C  +Y  K+T  M C G   
Sbjct: 131 APPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLE 190

Query: 204 GGKDTC 209
           GGKD+C
Sbjct: 191 GGKDSC 196


>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
           [Homo sapiens]
          Length = 256

 Score =  134 bits (337), Expect = 6e-32
 Identities = 81/221 (36%), Positives = 116/221 (52%), Gaps = 28/221 (12%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MW L+L+++  +  T A      +++ G EC  HSQPWQVA+Y  G  +CG  L+ P WV
Sbjct: 1   MW-LLLTLSFLLASTAAQD--GDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWV 57

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSH- 119
           L+AAHC  +  +V LG HNL + +   Q    S   PHP Y             E  SH 
Sbjct: 58  LSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRY-------------EARSHR 104

Query: 120 -DLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSI---EPEEFLRPRS----- 170
            D+MLLRL +PA++   V+   LPT+ P  G  C  SGWG +   EP     PRS     
Sbjct: 105 NDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLP 164

Query: 171 --LQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTC 209
             L C ++ ++S+  C ++Y  ++T  M+CAG    G ++C
Sbjct: 165 DTLHCANISIISDTSCDKSYPGRLTNTMVCAGAEGRGAESC 205


>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
           sapiens]
          Length = 253

 Score =  131 bits (330), Expect = 4e-31
 Identities = 76/206 (36%), Positives = 108/206 (52%), Gaps = 16/206 (7%)

Query: 4   LVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTA 63
           L+LS+AL    T        +I+ G  C + S PWQVA+ S    HCGGVLV+ +WVLTA
Sbjct: 12  LLLSLALE---TAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68

Query: 64  AHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLML 123
           AHC      V LG   L +     QR+  S SF HP Y+            +   +DLML
Sbjct: 69  AHCKMNEYTVHLGSDTLGDRR--AQRIKASKSFRHPGYST-----------QTHVNDLML 115

Query: 124 LRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDM 183
           ++L+  A+++ +VK + LP++    GTTC  SGWG+    +   P  L CV + L+S   
Sbjct: 116 VKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQD 175

Query: 184 CARAYSEKVTEFMLCAGLWTGGKDTC 209
           C + Y + +   MLCAG+    K+ C
Sbjct: 176 CTKVYKDLLENSMLCAGIPDSKKNAC 201


>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
           sapiens]
          Length = 253

 Score =  131 bits (330), Expect = 4e-31
 Identities = 76/206 (36%), Positives = 108/206 (52%), Gaps = 16/206 (7%)

Query: 4   LVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTA 63
           L+LS+AL    T        +I+ G  C + S PWQVA+ S    HCGGVLV+ +WVLTA
Sbjct: 12  LLLSLALE---TAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68

Query: 64  AHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLML 123
           AHC      V LG   L +     QR+  S SF HP Y+            +   +DLML
Sbjct: 69  AHCKMNEYTVHLGSDTLGDRR--AQRIKASKSFRHPGYST-----------QTHVNDLML 115

Query: 124 LRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDM 183
           ++L+  A+++ +VK + LP++    GTTC  SGWG+    +   P  L CV + L+S   
Sbjct: 116 VKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQD 175

Query: 184 CARAYSEKVTEFMLCAGLWTGGKDTC 209
           C + Y + +   MLCAG+    K+ C
Sbjct: 176 CTKVYKDLLENSMLCAGIPDSKKNAC 201


>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  131 bits (330), Expect = 4e-31
 Identities = 71/189 (37%), Positives = 109/189 (57%), Gaps = 14/189 (7%)

Query: 23  SRIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
           SRI+ G +C+ H+QPWQ A+       +CG VLVHPQW+LTAAHC KK  +V LG ++L 
Sbjct: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124

Query: 82  EPEDTGQRVPVS-HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140
              ++GQ++     S PHP Y+               S+DLML++L+   + T  V+ + 
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIKLNRRIRPTKDVRPIN 173

Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAG 200
           + +  P+ GT C  SGWG+ +  +   P+ LQC+++ +LS   C  AY  ++ + M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233

Query: 201 LWTGGKDTC 209
               G+D+C
Sbjct: 234 -DKAGRDSC 241


>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  131 bits (330), Expect = 4e-31
 Identities = 71/189 (37%), Positives = 109/189 (57%), Gaps = 14/189 (7%)

Query: 23  SRIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
           SRI+ G +C+ H+QPWQ A+       +CG VLVHPQW+LTAAHC KK  +V LG ++L 
Sbjct: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124

Query: 82  EPEDTGQRVPVS-HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140
              ++GQ++     S PHP Y+               S+DLML++L+   + T  V+ + 
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIKLNRRIRPTKDVRPIN 173

Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAG 200
           + +  P+ GT C  SGWG+ +  +   P+ LQC+++ +LS   C  AY  ++ + M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233

Query: 201 LWTGGKDTC 209
               G+D+C
Sbjct: 234 -DKAGRDSC 241


>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  131 bits (330), Expect = 4e-31
 Identities = 71/189 (37%), Positives = 109/189 (57%), Gaps = 14/189 (7%)

Query: 23  SRIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
           SRI+ G +C+ H+QPWQ A+       +CG VLVHPQW+LTAAHC KK  +V LG ++L 
Sbjct: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124

Query: 82  EPEDTGQRVPVS-HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140
              ++GQ++     S PHP Y+               S+DLML++L+   + T  V+ + 
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIKLNRRIRPTKDVRPIN 173

Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAG 200
           + +  P+ GT C  SGWG+ +  +   P+ LQC+++ +LS   C  AY  ++ + M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233

Query: 201 LWTGGKDTC 209
               G+D+C
Sbjct: 234 -DKAGRDSC 241


>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
          Length = 254

 Score =  126 bits (317), Expect = 1e-29
 Identities = 76/204 (37%), Positives = 102/204 (50%), Gaps = 10/204 (4%)

Query: 6   LSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAH 65
           LSI L +   G       +I  G EC ++SQPWQV ++      CGGVL+  +WVLTAAH
Sbjct: 3   LSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62

Query: 66  CLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLR 125
           C      V LG H+L + + T Q      S  HP Y  +   H+         HDL LLR
Sbjct: 63  CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHE---------HDLRLLR 113

Query: 126 LSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185
           L  P ++T  V+ L LP      GT C+ SGWG         P  LQC++L ++S+  C 
Sbjct: 114 LRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCH 173

Query: 186 RAYSEKVTEFMLCAGLWTGGKDTC 209
             Y  ++T  M+CAG    G+D C
Sbjct: 174 GVYPGRITSNMVCAG-GVPGQDAC 196


>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
          Length = 248

 Score =  126 bits (317), Expect = 1e-29
 Identities = 76/204 (37%), Positives = 102/204 (50%), Gaps = 10/204 (4%)

Query: 6   LSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAH 65
           LSI L +   G       +I  G EC ++SQPWQV ++      CGGVL+  +WVLTAAH
Sbjct: 3   LSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62

Query: 66  CLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLR 125
           C      V LG H+L + + T Q      S  HP Y  +   H+         HDL LLR
Sbjct: 63  CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHE---------HDLRLLR 113

Query: 126 LSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185
           L  P ++T  V+ L LP      GT C+ SGWG         P  LQC++L ++S+  C 
Sbjct: 114 LRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCH 173

Query: 186 RAYSEKVTEFMLCAGLWTGGKDTC 209
             Y  ++T  M+CAG    G+D C
Sbjct: 174 GVYPGRITSNMVCAG-GVPGQDAC 196


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,824,676
Number of Sequences: 37866
Number of extensions: 451576
Number of successful extensions: 1290
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 860
Number of HSP's gapped (non-prelim): 199
length of query: 223
length of database: 18,247,518
effective HSP length: 98
effective length of query: 125
effective length of database: 14,536,650
effective search space: 1817081250
effective search space used: 1817081250
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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