Search of human proteins with 5032313

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5032313 dystrophin Dp140bc isoform [Homo sapiens]
         (1133 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5032313 dystrophin Dp140bc isoform [Homo sapiens]                 2266   0.0  
gi|5032307 dystrophin Dp140c isoform [Homo sapiens]                  2180   0.0  
gi|5032311 dystrophin Dp140ab isoform [Homo sapiens]                 1913   0.0  
gi|5032281 dystrophin Dp427c isoform [Homo sapiens]                  1908   0.0  
gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens]                 1908   0.0  
gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens]               1908   0.0  
gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens]                 1908   0.0  
gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]                 1908   0.0  
gi|5032309 dystrophin Dp140b isoform [Homo sapiens]                  1908   0.0  
gi|5032293 dystrophin Dp140 isoform [Homo sapiens]                   1908   0.0  
gi|5032285 dystrophin Dp427l isoform [Homo sapiens]                  1908   0.0  
gi|5032283 dystrophin Dp427m isoform [Homo sapiens]                  1908   0.0  
gi|5032295 dystrophin Dp116 isoform [Homo sapiens]                   1363   0.0  
gi|110611228 utrophin [Homo sapiens]                                 1170   0.0  
gi|148539558 dystrophin related protein 2 [Homo sapiens]              801   0.0  
gi|5032303 dystrophin Dp71ab isoform [Homo sapiens]                   701   0.0  
gi|5032301 dystrophin Dp71a isoform [Homo sapiens]                    701   0.0  
gi|5032299 dystrophin Dp71b isoform [Homo sapiens]                    696   0.0  
gi|5032297 dystrophin Dp71 isoform [Homo sapiens]                     696   0.0  
gi|5032305 dystrophin Dp40 isoform [Homo sapiens]                     693   0.0  
gi|15147341 dystrobrevin, beta isoform 3 [Homo sapiens]               161   4e-39
gi|37577097 dystrobrevin, beta isoform 5 [Homo sapiens]               158   2e-38
gi|157364926 dystrotelin [Homo sapiens]                               156   9e-38
gi|42717999 dystrobrevin alpha isoform 2 [Homo sapiens]               149   2e-35
gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens]               148   3e-35
gi|42718003 dystrobrevin alpha isoform 3 [Homo sapiens]               148   3e-35
gi|42718001 dystrobrevin alpha isoform 4 [Homo sapiens]               148   3e-35
gi|42717997 dystrobrevin alpha isoform 5 [Homo sapiens]               148   3e-35
gi|42717994 dystrobrevin alpha isoform 7 [Homo sapiens]               148   3e-35
gi|189571587 dystrobrevin alpha isoform 9 [Homo sapiens]              148   3e-35

>gi|5032313 dystrophin Dp140bc isoform [Homo sapiens]
          Length = 1133

 Score = 2266 bits (5871), Expect = 0.0
 Identities = 1133/1133 (100%), Positives = 1133/1133 (100%)

Query: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60
            MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL
Sbjct: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60

Query: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120
            EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK
Sbjct: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120

Query: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
            DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA
Sbjct: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180

Query: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240
            NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK
Sbjct: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240

Query: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300
            FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ
Sbjct: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300

Query: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360
            KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW
Sbjct: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360

Query: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420
            LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG
Sbjct: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420

Query: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480
            LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ
Sbjct: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480

Query: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540
            EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR
Sbjct: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540

Query: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600
            QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP
Sbjct: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600

Query: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660
            WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC
Sbjct: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660

Query: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720
            LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN
Sbjct: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720

Query: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780
            WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD
Sbjct: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780

Query: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840
            SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR
Sbjct: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840

Query: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900
            VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC
Sbjct: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900

Query: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNLQAEYDRLKQQ 960
            TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNLQAEYDRLKQQ
Sbjct: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNLQAEYDRLKQQ 960

Query: 961  HEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQL 1020
            HEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQL
Sbjct: 961  HEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQL 1020

Query: 1021 HRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQ 1080
            HRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQ
Sbjct: 1021 HRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQ 1080

Query: 1081 DTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAMESLVSVMTDEEGAE 1133
            DTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAMESLVSVMTDEEGAE
Sbjct: 1081 DTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAMESLVSVMTDEEGAE 1133


>gi|5032307 dystrophin Dp140c isoform [Homo sapiens]
          Length = 1105

 Score = 2180 bits (5648), Expect = 0.0
 Identities = 1093/1104 (99%), Positives = 1093/1104 (99%), Gaps = 10/1104 (0%)

Query: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60
            MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL
Sbjct: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60

Query: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120
            EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK
Sbjct: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120

Query: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
            DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA
Sbjct: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180

Query: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240
            NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK
Sbjct: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240

Query: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300
            FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ
Sbjct: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300

Query: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360
            KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW
Sbjct: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360

Query: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420
            LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG
Sbjct: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420

Query: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480
            LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ
Sbjct: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480

Query: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540
            EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR
Sbjct: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540

Query: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600
            QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP
Sbjct: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600

Query: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660
            WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC
Sbjct: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660

Query: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720
            LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN
Sbjct: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720

Query: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780
            WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD
Sbjct: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780

Query: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840
            SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR
Sbjct: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840

Query: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900
            VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC
Sbjct: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900

Query: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNLQAEYDRLKQQ 960
            TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ          NLQAEYDRLKQQ
Sbjct: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ----------NLQAEYDRLKQQ 950

Query: 961  HEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQL 1020
            HEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQL
Sbjct: 951  HEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQL 1010

Query: 1021 HRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQ 1080
            HRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQ
Sbjct: 1011 HRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQ 1070

Query: 1081 DTSTGLEEVMEQLNNSFPSSRGHN 1104
            DTSTGLEEVMEQLNNSFPSSRG N
Sbjct: 1071 DTSTGLEEVMEQLNNSFPSSRGRN 1094


>gi|5032311 dystrophin Dp140ab isoform [Homo sapiens]
          Length = 1230

 Score = 1913 bits (4955), Expect = 0.0
 Identities = 970/1060 (91%), Positives = 988/1060 (93%), Gaps = 39/1060 (3%)

Query: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60
            MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL
Sbjct: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60

Query: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120
            EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK
Sbjct: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120

Query: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
            DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA
Sbjct: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180

Query: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240
            NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK
Sbjct: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240

Query: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300
            FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ
Sbjct: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300

Query: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360
            KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW
Sbjct: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360

Query: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420
            LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG
Sbjct: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420

Query: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480
            LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ
Sbjct: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480

Query: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540
            EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR
Sbjct: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540

Query: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600
            QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP
Sbjct: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600

Query: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660
            WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC
Sbjct: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660

Query: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720
            LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN
Sbjct: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720

Query: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780
            WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD
Sbjct: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780

Query: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840
            SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR
Sbjct: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840

Query: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900
            VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC
Sbjct: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900

Query: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET---NLQAEYDRL 957
            TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET   + Q  +D  
Sbjct: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPASSPQLSHDDT 960

Query: 958  KQQHEHKG-------------LSPLPSPPEMMP-------------------TSPQSPRD 985
              + EH               L+   SP E +                    + P+SP  
Sbjct: 961  HSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQ 1020

Query: 986  AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQ 1025
              +  E+    + +G LE  +  LE+ N+ L+++  RL+Q
Sbjct: 1021 ILISLES----EERGELERILADLEEENRNLQAEYDRLKQ 1056



 Score =  365 bits (936), Expect = e-100
 Identities = 188/193 (97%), Positives = 189/193 (97%), Gaps = 2/193 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 1040 LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1097

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 1098 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1157

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAME 1120
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAME
Sbjct: 1158 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAME 1217

Query: 1121 SLVSVMTDEEGAE 1133
            SLVSVMTDEEGAE
Sbjct: 1218 SLVSVMTDEEGAE 1230


>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
          Length = 3677

 Score = 1908 bits (4943), Expect = 0.0
 Identities = 970/1073 (90%), Positives = 988/1073 (92%), Gaps = 52/1073 (4%)

Query: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60
            MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL
Sbjct: 2453 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 2512

Query: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120
            EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK
Sbjct: 2513 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 2572

Query: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
            DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA
Sbjct: 2573 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2632

Query: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240
            NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK
Sbjct: 2633 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 2692

Query: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300
            FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ
Sbjct: 2693 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 2752

Query: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360
            KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW
Sbjct: 2753 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 2812

Query: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420
            LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG
Sbjct: 2813 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 2872

Query: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480
            LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ
Sbjct: 2873 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 2932

Query: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540
            EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR
Sbjct: 2933 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 2992

Query: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600
            QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP
Sbjct: 2993 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 3052

Query: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660
            WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC
Sbjct: 3053 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 3112

Query: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720
            LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN
Sbjct: 3113 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 3172

Query: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780
            WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD
Sbjct: 3173 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 3232

Query: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840
            SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR
Sbjct: 3233 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 3292

Query: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900
            VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC
Sbjct: 3293 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 3352

Query: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNL---------- 950
            TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET +          
Sbjct: 3353 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 3412

Query: 951  ------QAEYDRLKQQHEHKG-------------LSPLPSPPEMMP-------------- 977
                  Q  +D    + EH               L+   SP E +               
Sbjct: 3413 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 3472

Query: 978  -----TSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQ 1025
                 + P+SP    +  E+    + +G LE  +  LE+ N+ L+++  RL+Q
Sbjct: 3473 QDSPLSQPRSPAQILISLES----EERGELERILADLEEENRNLQAEYDRLKQ 3521



 Score =  306 bits (785), Expect = 6e-83
 Identities = 158/164 (96%), Positives = 159/164 (96%), Gaps = 2/164 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 3505 LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 3562

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 3563 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 3622

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1104
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N
Sbjct: 3623 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 3666



 Score =  100 bits (249), Expect = 8e-21
 Identities = 166/775 (21%), Positives = 312/775 (40%), Gaps = 89/775 (11%)

Query: 20   TELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKN 79
            T ++  L  ++Q++ +  +   D ED+ +     K     L+Q   +++ +I + +    
Sbjct: 1997 THVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRID-IIHSKKTAAL 2055

Query: 80   KTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM----------LKDSTQWLEAK 129
            +++    R  + + + ++  QW++V +  ++R+ + +            +K   QWL   
Sbjct: 2056 QSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLT-- 2113

Query: 130  EEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLR 189
             EAEQ L + +   E+W+   Y            K+L   + Q QT V   N    ++++
Sbjct: 2114 -EAEQFLRKTQIP-ENWEHAKYK--------WYLKELQDGIGQRQTVVRTLNATGEEIIQ 2163

Query: 190  DYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE 249
              S  D   +     ++N  W+ + K++S+R+  LEE   +L +F  DL +F+ WL EA+
Sbjct: 2164 QSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEAD 2223

Query: 250  TTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGS 309
              A++  +  ++++L E  + VK L+++    QG       +   L+E    +L S   S
Sbjct: 2224 NIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQG-------ILKQLNETGGPVLVSAPIS 2276

Query: 310  -DDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQE-------LLVWL 361
             ++   L+ +L   N +W ++ +     +  +EA      +L   L++       LL+WL
Sbjct: 2277 PEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWL 2336

Query: 362  Q--LKDDELSRQAPIGGDFP------AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVR 410
                   E+  Q    G F       AVQ KQ DV     +   L  ++P        + 
Sbjct: 2337 SPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLE 2396

Query: 411  IFLTEQPLEGLEKLYQEPRELPPE----------ERAQNVTRLLRKQAEEVNTEWEKLNL 460
               +E   + + +L QE R   P+             Q VT L+ +      T   KL +
Sbjct: 2397 DLSSE--WKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEM 2453

Query: 461  HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 520
             S+    ++    +  +   E TD L L     +VIK     VGDL  + + + + K KA
Sbjct: 2454 PSS-LMLEVPALADFNRAWTELTDWLSL---LDQVIKSQRVMVGDL--EDINEMIIKQKA 2507

Query: 521  LRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQL 578
               ++   +  +  +   A+ L           + T  +E +  +W  +Q  +++R +QL
Sbjct: 2508 TMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQL 2567

Query: 579  HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638
            +E  +D    S  +L    +       +  K+  +      T      K+TE  Q   DL
Sbjct: 2568 NEMLKD----STQWLEAKEEAEQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDL 2622

Query: 639  NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698
               + +          +   L L LL   +A D    H + +N        I   ++   
Sbjct: 2623 RQWQTNV--------DVANDLALKLLRDYSADDTRKVHMITENIN-ASWRSIHKRVSERE 2673

Query: 699  DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 748
              LE+ H  L   PL ++  L WL     T       T + R+L    G+  L K
Sbjct: 2674 AALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2728



 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 109/561 (19%), Positives = 234/561 (41%), Gaps = 59/561 (10%)

Query: 22   LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81
            L  W++ +D  +K +   +GD E + + + + +  + D++  +P L  +    Q +KN+ 
Sbjct: 1052 LKKWMAEVDVFLKEEWPALGDSEILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEA 1111

Query: 82   SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141
              + A  + T+ ++ +  QWD + + +  R++ L   L+ +    +   E  + + QA  
Sbjct: 1112 EPEFASRLETE-LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1170

Query: 142  KLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYS--ADDTRKV 199
            +         T D +QK + E K+  ++ +Q +  V +  +    ++      A +  K 
Sbjct: 1171 EYLERDFEYKTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKK 1230

Query: 200  HMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE----TTANVL 255
             + T   N  W  +  R++ +   LEE      +    LEK   WL E E    TT N+ 
Sbjct: 1231 ELETLTTNYQW--LCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIP 1288

Query: 256  QDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLL 315
              A   E + E    ++ LM+  +D   +I                     +G     L+
Sbjct: 1289 GGA---EEISEVLDSLENLMRHSEDNPNQIRILAQTL-------------TDGGVMDELI 1332

Query: 316  QRRLDNMNFKWSELRKKSLN----IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQ 371
               L+  N +W EL ++++     +   ++++ +  K LHL +QE L ++   D +L+  
Sbjct: 1333 NEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHL-IQESLTFI---DKQLA-- 1386

Query: 372  APIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 431
            A I     A Q   +  +            I S L +  I L E       K + + +E 
Sbjct: 1387 AYIADKVDAAQMPQEAQK------------IQSDLTSHEISLEEM------KKHNQGKE- 1427

Query: 432  PPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLR 491
               +R  +   + +K+ ++V+ ++ +L    A++++++ E+   L E++     L+ K  
Sbjct: 1428 -AAQRVLSQIDVAQKKLQDVSMKF-RLFQKPANFEQRLQESKMILDEVKMHLPALETKSV 1485

Query: 492  QAEVIKGSWQPVGDLL--IDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQL 549
            + EV++       +L   +  ++  +E V     +I   K+   +  +L  ++T L +  
Sbjct: 1486 EQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQ-KKQTENPKELDERVTALKLHY 1544

Query: 550  SPYNLSTLEDLNTRWKLLQVA 570
            +       E      K L+++
Sbjct: 1545 NELGAKVTERKQQLEKCLKLS 1565



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 70/339 (20%), Positives = 133/339 (39%), Gaps = 22/339 (6%)

Query: 3   SSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQ 62
           SSLM     L  +  A  E+  WL   +  +++Q  +  D+E + +     +  M DL  
Sbjct: 324 SSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTA 383

Query: 63  RRPQLEELITAAQNL--------KNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQ 114
            + ++  ++     L          +T  QE   ++  R E ++    E Q +L      
Sbjct: 384 HQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMD 443

Query: 115 L-NEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173
           L N+ LK+   WL   EE  +       K+E    GP  ++ +++++ + K L +DL Q 
Sbjct: 444 LQNQKLKELNDWLTKTEERTR-------KMEEEPLGP-DLEDLKRQVQQHKVLQEDLEQE 495

Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233
           Q  V+    + + +        T  +    + +   W +I +   +R   L++     Q+
Sbjct: 496 QVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQDILLKWQR 555

Query: 234 FPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYH 293
              +   F AWL+E E   N +     K     D   +   +++   L+ ++E       
Sbjct: 556 LTEEQCLFSAWLSEKEDAVNKIHTTGFK-----DQNEMLSSLQKLAVLKADLEKKKQSMG 610

Query: 294 NLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332
            L    Q +L +L+        +  LDN    W  L +K
Sbjct: 611 KLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQK 649



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 104/571 (18%), Positives = 222/571 (38%), Gaps = 46/571 (8%)

Query: 20   TELTDWLSLLDQVIKSQRVMV----GDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQ 75
            TEL  W++  + V++S    +    G+  D+ E   K  A  ++  ++  +L++   +AQ
Sbjct: 721  TELHSWITRSEAVLQSPEFAIFRKEGNFSDLKE---KVNAIEREKAEKFRKLQDASRSAQ 777

Query: 76   NLKNKTSNQEART-IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQ 134
             L  +  N+      I    E++ ++W E  + L  R   L E   +   +    ++ EQ
Sbjct: 778  ALVEQMVNEGVNADSIKQASEQLNSRWIEFCQLLSERLNWL-EYQNNIIAFYNQLQQLEQ 836

Query: 135  VLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSAD 194
            +   A   L+     P    AI+ ++   K     L   Q  ++     ++ L       
Sbjct: 837  MTTTAENWLKIQPTTPSEPTAIKSQLKICKDEVNRLSGLQPQIERLKIQSIALKEKGQGP 896

Query: 195  DTRKVHMITENINASWRSIHKRVSEREAALEETHRLL--QQFPLDLEKFLAWLTEAETTA 252
                   +       ++ +   V  RE  L+     L   ++   +     W+ ++ET  
Sbjct: 897  MFLDADFVA--FTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKL 954

Query: 253  NVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDA 312
            ++ Q +     ++E   G      + Q LQ  ++      + L    +++ +    S+ +
Sbjct: 955  SIPQLSVTDYEIMEQRLG------ELQALQSSLQEQQSGLYYLSTTVKEMSKKAP-SEIS 1007

Query: 313  VLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372
               Q   + +  +W +L  + +     LE   ++ +++   +Q L  W+   D  L  + 
Sbjct: 1008 RKYQSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEW 1067

Query: 373  PIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP 432
            P  GD   ++KQ    R    +++T +P + S              EG +K+     E  
Sbjct: 1068 PALGDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAE 1112

Query: 433  PEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQ 492
            PE  ++     L  + +E+NT+W+ +       +  +   LE+   LQ+   E+   + Q
Sbjct: 1113 PEFASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQ 1167

Query: 493  A--EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLS 550
            A  E ++  ++       D LQ  +E++K  + E    +  V  + +    +      ++
Sbjct: 1168 AEEEYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVA 1224

Query: 551  PYNL-STLEDLNTRWKLLQVAVEDRVRQLHE 580
               L   LE L T ++ L   +  + + L E
Sbjct: 1225 QEALKKELETLTTNYQWLCTRLNGKCKTLEE 1255



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 74/446 (16%), Positives = 186/446 (41%), Gaps = 40/446 (8%)

Query: 58   QDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNE 117
            + L + + ++E +I   + +  K   +  + +  +R+  ++  ++E+   +  R+QQL +
Sbjct: 1502 KSLSEVKSEVEMVIKTGRQIVQKKQTENPKEL-DERVTALKLHYNELGAKVTERKQQLEK 1560

Query: 118  MLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNV 177
             LK S +  +      + L     +L            +  ++   K   K++ + + ++
Sbjct: 1561 CLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHL 1620

Query: 178  DVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLD 237
                ++   L       +T     ++  +N++W ++  R  E    L E  + ++ F  +
Sbjct: 1621 KSITEVGEALKTVLGKKETLVEDKLSL-LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQN 1679

Query: 238  LEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDE 297
            ++    W+ +A+T    L D + K++  +    +K L  +  D++ ++++  D   NL  
Sbjct: 1680 VDHITKWIIQADT----LLDESEKKKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANLMA 1735

Query: 298  NSQKILRSLEGSDDAVLLQRRLDNMNFKWSELR------KKSLNIRSHLEASSDQWKRLH 351
            N         G     L++ ++  +N +++ +       K S+ ++   + +SD  K L 
Sbjct: 1736 N--------RGDHCRKLVEPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1787

Query: 352  LSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRI 411
                E+   + LK+++ ++              N+ +    +EL  +   +   +   R 
Sbjct: 1788 PLEAEIQQGVNLKEEDFNKD------------MNEDNEGTVKELLQRGDNLQQRITDER- 1834

Query: 412  FLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDE 471
                + ++  ++L Q       + R+Q      RK+A E++ +W +    + D  + +D+
Sbjct: 1835 --KREEIKIKQQLLQTKHNALKDLRSQR-----RKKALEISHQWYQYKRQADDLLKCLDD 1887

Query: 472  TLERLQELQEATDELDLKLRQAEVIK 497
              ++L  L E  DE  +K    E+ K
Sbjct: 1888 IEKKLASLPEPRDERKIKEIDRELQK 1913



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 96/533 (18%), Positives = 216/533 (40%), Gaps = 75/533 (14%)

Query: 12   LADFNRAWTELTDWL----SLLDQVIKSQRVMVGDLEDINEMI----------IKQKATM 57
            L  FN  W EL +       LL+Q I+S +     L  I E +          I  K   
Sbjct: 1336 LETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQESLTFIDKQLAAYIADKVDA 1395

Query: 58   QDLEQRRPQLEELITA----AQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQ 113
              + Q   +++  +T+     + +K     +EA        +R+ +Q D  Q+ LQ+   
Sbjct: 1396 AQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAA-------QRVLSQIDVAQKKLQDVSM 1448

Query: 114  QLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173
            +   + +    + +  +E++ +L + +  L + +      + +Q ++     L K L + 
Sbjct: 1449 KFR-LFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSLSEV 1507

Query: 174  QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233
            ++ V++      ++++    ++ +++      +   +  +  +V+ER+  LE+  +L ++
Sbjct: 1508 KSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNELGAKVTERKQQLEKCLKLSRK 1567

Query: 234  FPLDLEKFLAWL--TEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDV 291
               ++     WL  T+ E T     +        E + G K   K+ +  +  +++ T+V
Sbjct: 1568 MRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWG-KATQKEIEKQKVHLKSITEV 1626

Query: 292  YHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLH 351
                     + L+++ G  +  L++ +L  +N  W  +  ++    + L       +   
Sbjct: 1627 --------GEALKTVLGKKE-TLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFD 1677

Query: 352  LSLQELLVWLQLKD---DELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 408
             ++  +  W+   D   DE  ++ P        Q++ DV +  K EL    P + ST + 
Sbjct: 1678 QNVDHITKWIIQADTLLDESEKKKP--------QQKEDVLKRLKAELNDIRPKVDSTRDQ 1729

Query: 409  VRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLR--------KQAEEVNTEWEKL-- 458
                +  +  +   KL  EP+      R   ++  ++        K+ E+ N++ +KL  
Sbjct: 1730 AANLMANRG-DHCRKLV-EPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1787

Query: 459  ----------NLHSADWQRKIDETLE-RLQELQEATDELDLKL---RQAEVIK 497
                      NL   D+ + ++E  E  ++EL +  D L  ++   R+ E IK
Sbjct: 1788 PLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQQRITDERKREEIK 1840



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%)

Query: 286 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 340
           E H  ++H +  + Q  +   +G +     + R  +  +  +     S   RS     HL
Sbjct: 255 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 314

Query: 341 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 388
           EA  D+              R   +L+E+L WL   +D L  Q  I  D   V+ Q   H
Sbjct: 315 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 374

Query: 389 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 448
             +  +L   +  + + L+          L G  KL ++      EE        +++Q 
Sbjct: 375 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 416

Query: 449 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 503
             +N+ WE L + S + Q  +   L     ++L+EL +   + + + R+ E      +P+
Sbjct: 417 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 471

Query: 504 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 559
           G  L D L+  +++ K L+ +   L++    VN L   +  +      +  + LE+    
Sbjct: 472 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 527

Query: 560 LNTRWKLLQVAVEDR 574
           L  RW  +    EDR
Sbjct: 528 LGDRWANICRWTEDR 542


>gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens]
          Length = 2341

 Score = 1908 bits (4943), Expect = 0.0
 Identities = 970/1073 (90%), Positives = 988/1073 (92%), Gaps = 52/1073 (4%)

Query: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60
            MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL
Sbjct: 1117 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 1176

Query: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120
            EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK
Sbjct: 1177 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 1236

Query: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
            DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA
Sbjct: 1237 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 1296

Query: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240
            NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK
Sbjct: 1297 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 1356

Query: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300
            FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ
Sbjct: 1357 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 1416

Query: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360
            KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW
Sbjct: 1417 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 1476

Query: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420
            LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG
Sbjct: 1477 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 1536

Query: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480
            LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ
Sbjct: 1537 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 1596

Query: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540
            EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR
Sbjct: 1597 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 1656

Query: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600
            QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP
Sbjct: 1657 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 1716

Query: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660
            WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC
Sbjct: 1717 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 1776

Query: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720
            LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN
Sbjct: 1777 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 1836

Query: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780
            WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD
Sbjct: 1837 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 1896

Query: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840
            SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR
Sbjct: 1897 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 1956

Query: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900
            VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC
Sbjct: 1957 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 2016

Query: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNL---------- 950
            TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET +          
Sbjct: 2017 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 2076

Query: 951  ------QAEYDRLKQQHEHKG-------------LSPLPSPPEMMP-------------- 977
                  Q  +D    + EH               L+   SP E +               
Sbjct: 2077 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 2136

Query: 978  -----TSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQ 1025
                 + P+SP    +  E+    + +G LE  +  LE+ N+ L+++  RL+Q
Sbjct: 2137 QDSPLSQPRSPAQILISLES----EERGELERILADLEEENRNLQAEYDRLKQ 2185



 Score =  306 bits (785), Expect = 6e-83
 Identities = 158/164 (96%), Positives = 159/164 (96%), Gaps = 2/164 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 2169 LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 2226

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 2227 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 2286

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1104
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N
Sbjct: 2287 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 2330



 Score =  100 bits (249), Expect = 8e-21
 Identities = 166/775 (21%), Positives = 312/775 (40%), Gaps = 89/775 (11%)

Query: 20   TELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKN 79
            T ++  L  ++Q++ +  +   D ED+ +     K     L+Q   +++ +I + +    
Sbjct: 661  THVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRID-IIHSKKTAAL 719

Query: 80   KTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM----------LKDSTQWLEAK 129
            +++    R  + + + ++  QW++V +  ++R+ + +            +K   QWL   
Sbjct: 720  QSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLT-- 777

Query: 130  EEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLR 189
             EAEQ L + +   E+W+   Y            K+L   + Q QT V   N    ++++
Sbjct: 778  -EAEQFLRKTQIP-ENWEHAKYK--------WYLKELQDGIGQRQTVVRTLNATGEEIIQ 827

Query: 190  DYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE 249
              S  D   +     ++N  W+ + K++S+R+  LEE   +L +F  DL +F+ WL EA+
Sbjct: 828  QSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEAD 887

Query: 250  TTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGS 309
              A++  +  ++++L E  + VK L+++    QG       +   L+E    +L S   S
Sbjct: 888  NIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQG-------ILKQLNETGGPVLVSAPIS 940

Query: 310  -DDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQE-------LLVWL 361
             ++   L+ +L   N +W ++ +     +  +EA      +L   L++       LL+WL
Sbjct: 941  PEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWL 1000

Query: 362  Q--LKDDELSRQAPIGGDFP------AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVR 410
                   E+  Q    G F       AVQ KQ DV     +   L  ++P        + 
Sbjct: 1001 SPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLE 1060

Query: 411  IFLTEQPLEGLEKLYQEPRELPPE----------ERAQNVTRLLRKQAEEVNTEWEKLNL 460
               +E   + + +L QE R   P+             Q VT L+ +      T   KL +
Sbjct: 1061 DLSSE--WKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEM 1117

Query: 461  HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 520
             S+    ++    +  +   E TD L L     +VIK     VGDL  + + + + K KA
Sbjct: 1118 PSS-LMLEVPALADFNRAWTELTDWLSL---LDQVIKSQRVMVGDL--EDINEMIIKQKA 1171

Query: 521  LRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQL 578
               ++   +  +  +   A+ L           + T  +E +  +W  +Q  +++R +QL
Sbjct: 1172 TMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQL 1231

Query: 579  HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638
            +E  +D    S  +L    +       +  K+  +      T      K+TE  Q   DL
Sbjct: 1232 NEMLKD----STQWLEAKEEAEQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDL 1286

Query: 639  NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698
               + +          +   L L LL   +A D    H + +N        I   ++   
Sbjct: 1287 RQWQTNV--------DVANDLALKLLRDYSADDTRKVHMITENIN-ASWRSIHKRVSERE 1337

Query: 699  DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 748
              LE+ H  L   PL ++  L WL     T       T + R+L    G+  L K
Sbjct: 1338 AALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMK 1392



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 128/599 (21%), Positives = 244/599 (40%), Gaps = 58/599 (9%)

Query: 22  LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81
           LT+WL+  D  +  +  + G   +++  +   KAT +++E+++  L+ +    + LK   
Sbjct: 239 LTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHLKSITEVGEALKTVL 298

Query: 82  SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141
             +E  T++ D++  + + W  V    +     L E  K    + +  +   + + QA  
Sbjct: 299 GKKE--TLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADT 356

Query: 142 KL-ESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVH 200
            L ES K+ P      Q+K    K+L  +L   +  VD   D A  L+ +      + V 
Sbjct: 357 LLDESEKKKP------QQKEDVLKRLKAELNDIRPKVDSTRDQAANLMANRGDHCRKLVE 410

Query: 201 MITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANV-LQDAT 259
                +N  + +I  R+   +A++    + L+QF  D++K L  L EAE    V L++  
Sbjct: 411 PQISELNHRFAAISHRIKTGKASI--PLKELEQFNSDIQKLLEPL-EAEIQQGVNLKEED 467

Query: 260 RKERLLEDSKG-VKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRR 318
             + + ED++G VKEL+++  +LQ  I          DE  ++ ++  +      LLQ +
Sbjct: 468 FNKDMNEDNEGTVKELLQRGDNLQQRI---------TDERKREEIKIKQ-----QLLQTK 513

Query: 319 LDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDF 378
            + +    S+ RKK+L I       S QW +      +LL  L   + +L+   P   D 
Sbjct: 514 HNALKDLRSQRRKKALEI-------SHQWYQYKRQADDLLKCLDDIEKKLA-SLPEPRDE 565

Query: 379 PAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQ 438
             +++ +   +  K EL           E       E     L K ++E      + R  
Sbjct: 566 RKIKEIDRELQKKKEELNAVRRQAEGLSEDGAAMAVEPTQIQLSKRWREIESKFAQFRRL 625

Query: 439 NVTRL--LRKQAEEVNTEWEKLNLH--SADWQRKIDETLERLQELQEATDELDLKLRQAE 494
           N  ++  +R++   V TE   L +    + +  +I    + L E+++  +  DL  +  E
Sbjct: 626 NFAQIHTVREETMMVMTEDMPLEISYVPSTYLTEITHVSQALLEVEQLLNAPDLCAKDFE 685

Query: 495 VIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVN--DLARQLTTLGIQLSPY 552
            +    + + ++  DSLQ    ++  +  +     ++ + V    L   L+ L  Q    
Sbjct: 686 DLFKQEESLKNIK-DSLQQSSGRIDIIHSKKTAALQSATPVERVKLQEALSQLDFQ---- 740

Query: 553 NLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRD-------FGPASQHFLSTSVQGPWERA 604
                E +N  +K  Q   +  V +    H D          A Q    T +   WE A
Sbjct: 741 ----WEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLTEAEQFLRKTQIPENWEHA 795



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 87/493 (17%), Positives = 199/493 (40%), Gaps = 64/493 (12%)

Query: 34  KSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDR 93
           K     + D  D  +M  + +    DL      LEE+       K     +EA       
Sbjct: 47  KQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEM-------KKHNQGKEAA------ 93

Query: 94  IERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTV 153
            +R+ +Q D  Q+ LQ+   +   + +    + +  +E++ +L + +  L + +      
Sbjct: 94  -QRVLSQIDVAQKKLQDVSMKFR-LFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQ 151

Query: 154 DAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSI 213
           + +Q ++     L K L + ++ V++      ++++    ++ +++      +   +  +
Sbjct: 152 EVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNEL 211

Query: 214 HKRVSEREAALEETHRLLQQFPLDLEKFLAWL--TEAETTANVLQDATRKERLLEDSKGV 271
             +V+ER+  LE+  +L ++   ++     WL  T+ E T     +        E + G 
Sbjct: 212 GAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWG- 270

Query: 272 KELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRK 331
           K   K+ +  +  +++ T+V         + L+++ G  +  L++ +L  +N  W  +  
Sbjct: 271 KATQKEIEKQKVHLKSITEV--------GEALKTVLGKKE-TLVEDKLSLLNSNWIAVTS 321

Query: 332 KSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DELSRQAPIGGDFPAVQKQNDVH 388
           ++    + L       +    ++  +  W+   D   DE  ++ P        Q++ DV 
Sbjct: 322 RAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADTLLDESEKKKP--------QQKEDVL 373

Query: 389 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLR--- 445
           +  K EL    P + ST +     +  +  +   KL  EP+      R   ++  ++   
Sbjct: 374 KRLKAELNDIRPKVDSTRDQAANLMANRG-DHCRKLV-EPQISELNHRFAAISHRIKTGK 431

Query: 446 -----KQAEEVNTEWEKL------------NLHSADWQRKIDETLE-RLQELQEATDELD 487
                K+ E+ N++ +KL            NL   D+ + ++E  E  ++EL +  D L 
Sbjct: 432 ASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQ 491

Query: 488 LKL---RQAEVIK 497
            ++   R+ E IK
Sbjct: 492 QRITDERKREEIK 504


>gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens]
          Length = 2344

 Score = 1908 bits (4943), Expect = 0.0
 Identities = 970/1073 (90%), Positives = 988/1073 (92%), Gaps = 52/1073 (4%)

Query: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60
            MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL
Sbjct: 1120 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 1179

Query: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120
            EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK
Sbjct: 1180 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 1239

Query: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
            DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA
Sbjct: 1240 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 1299

Query: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240
            NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK
Sbjct: 1300 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 1359

Query: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300
            FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ
Sbjct: 1360 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 1419

Query: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360
            KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW
Sbjct: 1420 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 1479

Query: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420
            LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG
Sbjct: 1480 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 1539

Query: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480
            LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ
Sbjct: 1540 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 1599

Query: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540
            EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR
Sbjct: 1600 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 1659

Query: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600
            QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP
Sbjct: 1660 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 1719

Query: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660
            WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC
Sbjct: 1720 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 1779

Query: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720
            LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN
Sbjct: 1780 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 1839

Query: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780
            WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD
Sbjct: 1840 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 1899

Query: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840
            SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR
Sbjct: 1900 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 1959

Query: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900
            VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC
Sbjct: 1960 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 2019

Query: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNL---------- 950
            TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET +          
Sbjct: 2020 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 2079

Query: 951  ------QAEYDRLKQQHEHKG-------------LSPLPSPPEMMP-------------- 977
                  Q  +D    + EH               L+   SP E +               
Sbjct: 2080 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 2139

Query: 978  -----TSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQ 1025
                 + P+SP    +  E+    + +G LE  +  LE+ N+ L+++  RL+Q
Sbjct: 2140 QDSPLSQPRSPAQILISLES----EERGELERILADLEEENRNLQAEYDRLKQ 2188



 Score =  306 bits (785), Expect = 6e-83
 Identities = 158/164 (96%), Positives = 159/164 (96%), Gaps = 2/164 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 2172 LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 2229

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 2230 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 2289

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1104
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N
Sbjct: 2290 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 2333



 Score =  100 bits (249), Expect = 8e-21
 Identities = 166/775 (21%), Positives = 312/775 (40%), Gaps = 89/775 (11%)

Query: 20   TELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKN 79
            T ++  L  ++Q++ +  +   D ED+ +     K     L+Q   +++ +I + +    
Sbjct: 664  THVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRID-IIHSKKTAAL 722

Query: 80   KTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM----------LKDSTQWLEAK 129
            +++    R  + + + ++  QW++V +  ++R+ + +            +K   QWL   
Sbjct: 723  QSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLT-- 780

Query: 130  EEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLR 189
             EAEQ L + +   E+W+   Y            K+L   + Q QT V   N    ++++
Sbjct: 781  -EAEQFLRKTQIP-ENWEHAKYK--------WYLKELQDGIGQRQTVVRTLNATGEEIIQ 830

Query: 190  DYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE 249
              S  D   +     ++N  W+ + K++S+R+  LEE   +L +F  DL +F+ WL EA+
Sbjct: 831  QSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEAD 890

Query: 250  TTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGS 309
              A++  +  ++++L E  + VK L+++    QG       +   L+E    +L S   S
Sbjct: 891  NIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQG-------ILKQLNETGGPVLVSAPIS 943

Query: 310  -DDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQE-------LLVWL 361
             ++   L+ +L   N +W ++ +     +  +EA      +L   L++       LL+WL
Sbjct: 944  PEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWL 1003

Query: 362  Q--LKDDELSRQAPIGGDFP------AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVR 410
                   E+  Q    G F       AVQ KQ DV     +   L  ++P        + 
Sbjct: 1004 SPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLE 1063

Query: 411  IFLTEQPLEGLEKLYQEPRELPPE----------ERAQNVTRLLRKQAEEVNTEWEKLNL 460
               +E   + + +L QE R   P+             Q VT L+ +      T   KL +
Sbjct: 1064 DLSSE--WKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEM 1120

Query: 461  HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 520
             S+    ++    +  +   E TD L L     +VIK     VGDL  + + + + K KA
Sbjct: 1121 PSS-LMLEVPALADFNRAWTELTDWLSL---LDQVIKSQRVMVGDL--EDINEMIIKQKA 1174

Query: 521  LRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQL 578
               ++   +  +  +   A+ L           + T  +E +  +W  +Q  +++R +QL
Sbjct: 1175 TMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQL 1234

Query: 579  HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638
            +E  +D    S  +L    +       +  K+  +      T      K+TE  Q   DL
Sbjct: 1235 NEMLKD----STQWLEAKEEAEQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDL 1289

Query: 639  NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698
               + +          +   L L LL   +A D    H + +N        I   ++   
Sbjct: 1290 RQWQTNV--------DVANDLALKLLRDYSADDTRKVHMITENIN-ASWRSIHKRVSERE 1340

Query: 699  DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 748
              LE+ H  L   PL ++  L WL     T       T + R+L    G+  L K
Sbjct: 1341 AALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMK 1395



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 128/599 (21%), Positives = 244/599 (40%), Gaps = 58/599 (9%)

Query: 22  LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81
           LT+WL+  D  +  +  + G   +++  +   KAT +++E+++  L+ +    + LK   
Sbjct: 242 LTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHLKSITEVGEALKTVL 301

Query: 82  SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141
             +E  T++ D++  + + W  V    +     L E  K    + +  +   + + QA  
Sbjct: 302 GKKE--TLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADT 359

Query: 142 KL-ESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVH 200
            L ES K+ P      Q+K    K+L  +L   +  VD   D A  L+ +      + V 
Sbjct: 360 LLDESEKKKP------QQKEDVLKRLKAELNDIRPKVDSTRDQAANLMANRGDHCRKLVE 413

Query: 201 MITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANV-LQDAT 259
                +N  + +I  R+   +A++    + L+QF  D++K L  L EAE    V L++  
Sbjct: 414 PQISELNHRFAAISHRIKTGKASI--PLKELEQFNSDIQKLLEPL-EAEIQQGVNLKEED 470

Query: 260 RKERLLEDSKG-VKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRR 318
             + + ED++G VKEL+++  +LQ  I          DE  ++ ++  +      LLQ +
Sbjct: 471 FNKDMNEDNEGTVKELLQRGDNLQQRI---------TDERKREEIKIKQ-----QLLQTK 516

Query: 319 LDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDF 378
            + +    S+ RKK+L I       S QW +      +LL  L   + +L+   P   D 
Sbjct: 517 HNALKDLRSQRRKKALEI-------SHQWYQYKRQADDLLKCLDDIEKKLA-SLPEPRDE 568

Query: 379 PAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQ 438
             +++ +   +  K EL           E       E     L K ++E      + R  
Sbjct: 569 RKIKEIDRELQKKKEELNAVRRQAEGLSEDGAAMAVEPTQIQLSKRWREIESKFAQFRRL 628

Query: 439 NVTRL--LRKQAEEVNTEWEKLNLH--SADWQRKIDETLERLQELQEATDELDLKLRQAE 494
           N  ++  +R++   V TE   L +    + +  +I    + L E+++  +  DL  +  E
Sbjct: 629 NFAQIHTVREETMMVMTEDMPLEISYVPSTYLTEITHVSQALLEVEQLLNAPDLCAKDFE 688

Query: 495 VIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVN--DLARQLTTLGIQLSPY 552
            +    + + ++  DSLQ    ++  +  +     ++ + V    L   L+ L  Q    
Sbjct: 689 DLFKQEESLKNIK-DSLQQSSGRIDIIHSKKTAALQSATPVERVKLQEALSQLDFQ---- 743

Query: 553 NLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRD-------FGPASQHFLSTSVQGPWERA 604
                E +N  +K  Q   +  V +    H D          A Q    T +   WE A
Sbjct: 744 ----WEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLTEAEQFLRKTQIPENWEHA 798



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 87/493 (17%), Positives = 199/493 (40%), Gaps = 64/493 (12%)

Query: 34  KSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDR 93
           K     + D  D  +M  + +    DL      LEE+       K     +EA       
Sbjct: 50  KQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEM-------KKHNQGKEAA------ 96

Query: 94  IERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTV 153
            +R+ +Q D  Q+ LQ+   +   + +    + +  +E++ +L + +  L + +      
Sbjct: 97  -QRVLSQIDVAQKKLQDVSMKFR-LFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQ 154

Query: 154 DAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSI 213
           + +Q ++     L K L + ++ V++      ++++    ++ +++      +   +  +
Sbjct: 155 EVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNEL 214

Query: 214 HKRVSEREAALEETHRLLQQFPLDLEKFLAWL--TEAETTANVLQDATRKERLLEDSKGV 271
             +V+ER+  LE+  +L ++   ++     WL  T+ E T     +        E + G 
Sbjct: 215 GAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWG- 273

Query: 272 KELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRK 331
           K   K+ +  +  +++ T+V         + L+++ G  +  L++ +L  +N  W  +  
Sbjct: 274 KATQKEIEKQKVHLKSITEV--------GEALKTVLGKKE-TLVEDKLSLLNSNWIAVTS 324

Query: 332 KSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DELSRQAPIGGDFPAVQKQNDVH 388
           ++    + L       +    ++  +  W+   D   DE  ++ P        Q++ DV 
Sbjct: 325 RAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADTLLDESEKKKP--------QQKEDVL 376

Query: 389 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLR--- 445
           +  K EL    P + ST +     +  +  +   KL  EP+      R   ++  ++   
Sbjct: 377 KRLKAELNDIRPKVDSTRDQAANLMANRG-DHCRKLV-EPQISELNHRFAAISHRIKTGK 434

Query: 446 -----KQAEEVNTEWEKL------------NLHSADWQRKIDETLE-RLQELQEATDELD 487
                K+ E+ N++ +KL            NL   D+ + ++E  E  ++EL +  D L 
Sbjct: 435 ASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQ 494

Query: 488 LKL---RQAEVIK 497
            ++   R+ E IK
Sbjct: 495 QRITDERKREEIK 507


>gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens]
          Length = 3562

 Score = 1908 bits (4943), Expect = 0.0
 Identities = 970/1073 (90%), Positives = 988/1073 (92%), Gaps = 52/1073 (4%)

Query: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60
            MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL
Sbjct: 2338 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 2397

Query: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120
            EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK
Sbjct: 2398 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 2457

Query: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
            DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA
Sbjct: 2458 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2517

Query: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240
            NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK
Sbjct: 2518 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 2577

Query: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300
            FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ
Sbjct: 2578 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 2637

Query: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360
            KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW
Sbjct: 2638 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 2697

Query: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420
            LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG
Sbjct: 2698 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 2757

Query: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480
            LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ
Sbjct: 2758 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 2817

Query: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540
            EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR
Sbjct: 2818 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 2877

Query: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600
            QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP
Sbjct: 2878 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 2937

Query: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660
            WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC
Sbjct: 2938 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 2997

Query: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720
            LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN
Sbjct: 2998 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 3057

Query: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780
            WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD
Sbjct: 3058 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 3117

Query: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840
            SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR
Sbjct: 3118 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 3177

Query: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900
            VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC
Sbjct: 3178 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 3237

Query: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNL---------- 950
            TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET +          
Sbjct: 3238 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 3297

Query: 951  ------QAEYDRLKQQHEHKG-------------LSPLPSPPEMMP-------------- 977
                  Q  +D    + EH               L+   SP E +               
Sbjct: 3298 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 3357

Query: 978  -----TSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQ 1025
                 + P+SP    +  E+    + +G LE  +  LE+ N+ L+++  RL+Q
Sbjct: 3358 QDSPLSQPRSPAQILISLES----EERGELERILADLEEENRNLQAEYDRLKQ 3406



 Score =  306 bits (785), Expect = 6e-83
 Identities = 158/164 (96%), Positives = 159/164 (96%), Gaps = 2/164 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 3390 LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 3447

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 3448 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 3507

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1104
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N
Sbjct: 3508 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 3551



 Score =  100 bits (249), Expect = 8e-21
 Identities = 166/775 (21%), Positives = 312/775 (40%), Gaps = 89/775 (11%)

Query: 20   TELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKN 79
            T ++  L  ++Q++ +  +   D ED+ +     K     L+Q   +++ +I + +    
Sbjct: 1882 THVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRID-IIHSKKTAAL 1940

Query: 80   KTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM----------LKDSTQWLEAK 129
            +++    R  + + + ++  QW++V +  ++R+ + +            +K   QWL   
Sbjct: 1941 QSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLT-- 1998

Query: 130  EEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLR 189
             EAEQ L + +   E+W+   Y            K+L   + Q QT V   N    ++++
Sbjct: 1999 -EAEQFLRKTQIP-ENWEHAKYK--------WYLKELQDGIGQRQTVVRTLNATGEEIIQ 2048

Query: 190  DYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE 249
              S  D   +     ++N  W+ + K++S+R+  LEE   +L +F  DL +F+ WL EA+
Sbjct: 2049 QSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEAD 2108

Query: 250  TTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGS 309
              A++  +  ++++L E  + VK L+++    QG       +   L+E    +L S   S
Sbjct: 2109 NIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQG-------ILKQLNETGGPVLVSAPIS 2161

Query: 310  -DDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQE-------LLVWL 361
             ++   L+ +L   N +W ++ +     +  +EA      +L   L++       LL+WL
Sbjct: 2162 PEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWL 2221

Query: 362  Q--LKDDELSRQAPIGGDFP------AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVR 410
                   E+  Q    G F       AVQ KQ DV     +   L  ++P        + 
Sbjct: 2222 SPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLE 2281

Query: 411  IFLTEQPLEGLEKLYQEPRELPPE----------ERAQNVTRLLRKQAEEVNTEWEKLNL 460
               +E   + + +L QE R   P+             Q VT L+ +      T   KL +
Sbjct: 2282 DLSSE--WKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEM 2338

Query: 461  HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 520
             S+    ++    +  +   E TD L L     +VIK     VGDL  + + + + K KA
Sbjct: 2339 PSS-LMLEVPALADFNRAWTELTDWLSL---LDQVIKSQRVMVGDL--EDINEMIIKQKA 2392

Query: 521  LRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQL 578
               ++   +  +  +   A+ L           + T  +E +  +W  +Q  +++R +QL
Sbjct: 2393 TMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQL 2452

Query: 579  HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638
            +E  +D    S  +L    +       +  K+  +      T      K+TE  Q   DL
Sbjct: 2453 NEMLKD----STQWLEAKEEAEQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDL 2507

Query: 639  NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698
               + +          +   L L LL   +A D    H + +N        I   ++   
Sbjct: 2508 RQWQTNV--------DVANDLALKLLRDYSADDTRKVHMITENIN-ASWRSIHKRVSERE 2558

Query: 699  DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 748
              LE+ H  L   PL ++  L WL     T       T + R+L    G+  L K
Sbjct: 2559 AALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2613



 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 109/561 (19%), Positives = 234/561 (41%), Gaps = 59/561 (10%)

Query: 22   LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81
            L  W++ +D  +K +   +GD E + + + + +  + D++  +P L  +    Q +KN+ 
Sbjct: 937  LKKWMAEVDVFLKEEWPALGDSEILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEA 996

Query: 82   SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141
              + A  + T+ ++ +  QWD + + +  R++ L   L+ +    +   E  + + QA  
Sbjct: 997  EPEFASRLETE-LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1055

Query: 142  KLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYS--ADDTRKV 199
            +         T D +QK + E K+  ++ +Q +  V +  +    ++      A +  K 
Sbjct: 1056 EYLERDFEYKTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKK 1115

Query: 200  HMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE----TTANVL 255
             + T   N  W  +  R++ +   LEE      +    LEK   WL E E    TT N+ 
Sbjct: 1116 ELETLTTNYQW--LCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIP 1173

Query: 256  QDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLL 315
              A   E + E    ++ LM+  +D   +I                     +G     L+
Sbjct: 1174 GGA---EEISEVLDSLENLMRHSEDNPNQIRILAQTL-------------TDGGVMDELI 1217

Query: 316  QRRLDNMNFKWSELRKKSLN----IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQ 371
               L+  N +W EL ++++     +   ++++ +  K LHL +QE L ++   D +L+  
Sbjct: 1218 NEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHL-IQESLTFI---DKQLA-- 1271

Query: 372  APIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 431
            A I     A Q   +  +            I S L +  I L E       K + + +E 
Sbjct: 1272 AYIADKVDAAQMPQEAQK------------IQSDLTSHEISLEEM------KKHNQGKE- 1312

Query: 432  PPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLR 491
               +R  +   + +K+ ++V+ ++ +L    A++++++ E+   L E++     L+ K  
Sbjct: 1313 -AAQRVLSQIDVAQKKLQDVSMKF-RLFQKPANFEQRLQESKMILDEVKMHLPALETKSV 1370

Query: 492  QAEVIKGSWQPVGDLL--IDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQL 549
            + EV++       +L   +  ++  +E V     +I   K+   +  +L  ++T L +  
Sbjct: 1371 EQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQ-KKQTENPKELDERVTALKLHY 1429

Query: 550  SPYNLSTLEDLNTRWKLLQVA 570
            +       E      K L+++
Sbjct: 1430 NELGAKVTERKQQLEKCLKLS 1450



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 70/339 (20%), Positives = 133/339 (39%), Gaps = 22/339 (6%)

Query: 3   SSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQ 62
           SSLM     L  +  A  E+  WL   +  +++Q  +  D+E + +     +  M DL  
Sbjct: 209 SSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTA 268

Query: 63  RRPQLEELITAAQNL--------KNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQ 114
            + ++  ++     L          +T  QE   ++  R E ++    E Q +L      
Sbjct: 269 HQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMD 328

Query: 115 L-NEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173
           L N+ LK+   WL   EE  +       K+E    GP  ++ +++++ + K L +DL Q 
Sbjct: 329 LQNQKLKELNDWLTKTEERTR-------KMEEEPLGP-DLEDLKRQVQQHKVLQEDLEQE 380

Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233
           Q  V+    + + +        T  +    + +   W +I +   +R   L++     Q+
Sbjct: 381 QVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQDILLKWQR 440

Query: 234 FPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYH 293
              +   F AWL+E E   N +     K     D   +   +++   L+ ++E       
Sbjct: 441 LTEEQCLFSAWLSEKEDAVNKIHTTGFK-----DQNEMLSSLQKLAVLKADLEKKKQSMG 495

Query: 294 NLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332
            L    Q +L +L+        +  LDN    W  L +K
Sbjct: 496 KLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQK 534



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 104/571 (18%), Positives = 222/571 (38%), Gaps = 46/571 (8%)

Query: 20   TELTDWLSLLDQVIKSQRVMV----GDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQ 75
            TEL  W++  + V++S    +    G+  D+ E   K  A  ++  ++  +L++   +AQ
Sbjct: 606  TELHSWITRSEAVLQSPEFAIFRKEGNFSDLKE---KVNAIEREKAEKFRKLQDASRSAQ 662

Query: 76   NLKNKTSNQEART-IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQ 134
             L  +  N+      I    E++ ++W E  + L  R   L E   +   +    ++ EQ
Sbjct: 663  ALVEQMVNEGVNADSIKQASEQLNSRWIEFCQLLSERLNWL-EYQNNIIAFYNQLQQLEQ 721

Query: 135  VLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSAD 194
            +   A   L+     P    AI+ ++   K     L   Q  ++     ++ L       
Sbjct: 722  MTTTAENWLKIQPTTPSEPTAIKSQLKICKDEVNRLSGLQPQIERLKIQSIALKEKGQGP 781

Query: 195  DTRKVHMITENINASWRSIHKRVSEREAALEETHRLL--QQFPLDLEKFLAWLTEAETTA 252
                   +       ++ +   V  RE  L+     L   ++   +     W+ ++ET  
Sbjct: 782  MFLDADFVA--FTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKL 839

Query: 253  NVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDA 312
            ++ Q +     ++E   G      + Q LQ  ++      + L    +++ +    S+ +
Sbjct: 840  SIPQLSVTDYEIMEQRLG------ELQALQSSLQEQQSGLYYLSTTVKEMSKKAP-SEIS 892

Query: 313  VLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372
               Q   + +  +W +L  + +     LE   ++ +++   +Q L  W+   D  L  + 
Sbjct: 893  RKYQSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEW 952

Query: 373  PIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP 432
            P  GD   ++KQ    R    +++T +P + S              EG +K+     E  
Sbjct: 953  PALGDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAE 997

Query: 433  PEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQ 492
            PE  ++     L  + +E+NT+W+ +       +  +   LE+   LQ+   E+   + Q
Sbjct: 998  PEFASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQ 1052

Query: 493  A--EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLS 550
            A  E ++  ++       D LQ  +E++K  + E    +  V  + +    +      ++
Sbjct: 1053 AEEEYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVA 1109

Query: 551  PYNL-STLEDLNTRWKLLQVAVEDRVRQLHE 580
               L   LE L T ++ L   +  + + L E
Sbjct: 1110 QEALKKELETLTTNYQWLCTRLNGKCKTLEE 1140



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 74/446 (16%), Positives = 186/446 (41%), Gaps = 40/446 (8%)

Query: 58   QDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNE 117
            + L + + ++E +I   + +  K   +  + +  +R+  ++  ++E+   +  R+QQL +
Sbjct: 1387 KSLSEVKSEVEMVIKTGRQIVQKKQTENPKEL-DERVTALKLHYNELGAKVTERKQQLEK 1445

Query: 118  MLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNV 177
             LK S +  +      + L     +L            +  ++   K   K++ + + ++
Sbjct: 1446 CLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHL 1505

Query: 178  DVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLD 237
                ++   L       +T     ++  +N++W ++  R  E    L E  + ++ F  +
Sbjct: 1506 KSITEVGEALKTVLGKKETLVEDKLSL-LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQN 1564

Query: 238  LEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDE 297
            ++    W+ +A+T    L D + K++  +    +K L  +  D++ ++++  D   NL  
Sbjct: 1565 VDHITKWIIQADT----LLDESEKKKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANLMA 1620

Query: 298  NSQKILRSLEGSDDAVLLQRRLDNMNFKWSELR------KKSLNIRSHLEASSDQWKRLH 351
            N         G     L++ ++  +N +++ +       K S+ ++   + +SD  K L 
Sbjct: 1621 N--------RGDHCRKLVEPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1672

Query: 352  LSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRI 411
                E+   + LK+++ ++              N+ +    +EL  +   +   +   R 
Sbjct: 1673 PLEAEIQQGVNLKEEDFNKD------------MNEDNEGTVKELLQRGDNLQQRITDER- 1719

Query: 412  FLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDE 471
                + ++  ++L Q       + R+Q      RK+A E++ +W +    + D  + +D+
Sbjct: 1720 --KREEIKIKQQLLQTKHNALKDLRSQR-----RKKALEISHQWYQYKRQADDLLKCLDD 1772

Query: 472  TLERLQELQEATDELDLKLRQAEVIK 497
              ++L  L E  DE  +K    E+ K
Sbjct: 1773 IEKKLASLPEPRDERKIKEIDRELQK 1798



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 96/533 (18%), Positives = 216/533 (40%), Gaps = 75/533 (14%)

Query: 12   LADFNRAWTELTDWL----SLLDQVIKSQRVMVGDLEDINEMI----------IKQKATM 57
            L  FN  W EL +       LL+Q I+S +     L  I E +          I  K   
Sbjct: 1221 LETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQESLTFIDKQLAAYIADKVDA 1280

Query: 58   QDLEQRRPQLEELITA----AQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQ 113
              + Q   +++  +T+     + +K     +EA        +R+ +Q D  Q+ LQ+   
Sbjct: 1281 AQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAA-------QRVLSQIDVAQKKLQDVSM 1333

Query: 114  QLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173
            +   + +    + +  +E++ +L + +  L + +      + +Q ++     L K L + 
Sbjct: 1334 KFR-LFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSLSEV 1392

Query: 174  QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233
            ++ V++      ++++    ++ +++      +   +  +  +V+ER+  LE+  +L ++
Sbjct: 1393 KSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNELGAKVTERKQQLEKCLKLSRK 1452

Query: 234  FPLDLEKFLAWL--TEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDV 291
               ++     WL  T+ E T     +        E + G K   K+ +  +  +++ T+V
Sbjct: 1453 MRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWG-KATQKEIEKQKVHLKSITEV 1511

Query: 292  YHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLH 351
                     + L+++ G  +  L++ +L  +N  W  +  ++    + L       +   
Sbjct: 1512 --------GEALKTVLGKKE-TLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFD 1562

Query: 352  LSLQELLVWLQLKD---DELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 408
             ++  +  W+   D   DE  ++ P        Q++ DV +  K EL    P + ST + 
Sbjct: 1563 QNVDHITKWIIQADTLLDESEKKKP--------QQKEDVLKRLKAELNDIRPKVDSTRDQ 1614

Query: 409  VRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLR--------KQAEEVNTEWEKL-- 458
                +  +  +   KL  EP+      R   ++  ++        K+ E+ N++ +KL  
Sbjct: 1615 AANLMANRG-DHCRKLV-EPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1672

Query: 459  ----------NLHSADWQRKIDETLE-RLQELQEATDELDLKL---RQAEVIK 497
                      NL   D+ + ++E  E  ++EL +  D L  ++   R+ E IK
Sbjct: 1673 PLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQQRITDERKREEIK 1725



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%)

Query: 286 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 340
           E H  ++H +  + Q  +   +G +     + R  +  +  +     S   RS     HL
Sbjct: 140 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 199

Query: 341 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 388
           EA  D+              R   +L+E+L WL   +D L  Q  I  D   V+ Q   H
Sbjct: 200 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 259

Query: 389 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 448
             +  +L   +  + + L+          L G  KL ++      EE        +++Q 
Sbjct: 260 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 301

Query: 449 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 503
             +N+ WE L + S + Q  +   L     ++L+EL +   + + + R+ E      +P+
Sbjct: 302 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 356

Query: 504 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 559
           G  L D L+  +++ K L+ +   L++    VN L   +  +      +  + LE+    
Sbjct: 357 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 412

Query: 560 LNTRWKLLQVAVEDR 574
           L  RW  +    EDR
Sbjct: 413 LGDRWANICRWTEDR 427


>gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]
          Length = 3681

 Score = 1908 bits (4943), Expect = 0.0
 Identities = 970/1073 (90%), Positives = 988/1073 (92%), Gaps = 52/1073 (4%)

Query: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60
            MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL
Sbjct: 2457 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 2516

Query: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120
            EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK
Sbjct: 2517 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 2576

Query: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
            DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA
Sbjct: 2577 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2636

Query: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240
            NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK
Sbjct: 2637 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 2696

Query: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300
            FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ
Sbjct: 2697 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 2756

Query: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360
            KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW
Sbjct: 2757 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 2816

Query: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420
            LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG
Sbjct: 2817 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 2876

Query: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480
            LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ
Sbjct: 2877 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 2936

Query: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540
            EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR
Sbjct: 2937 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 2996

Query: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600
            QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP
Sbjct: 2997 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 3056

Query: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660
            WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC
Sbjct: 3057 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 3116

Query: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720
            LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN
Sbjct: 3117 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 3176

Query: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780
            WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD
Sbjct: 3177 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 3236

Query: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840
            SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR
Sbjct: 3237 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 3296

Query: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900
            VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC
Sbjct: 3297 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 3356

Query: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNL---------- 950
            TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET +          
Sbjct: 3357 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 3416

Query: 951  ------QAEYDRLKQQHEHKG-------------LSPLPSPPEMMP-------------- 977
                  Q  +D    + EH               L+   SP E +               
Sbjct: 3417 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 3476

Query: 978  -----TSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQ 1025
                 + P+SP    +  E+    + +G LE  +  LE+ N+ L+++  RL+Q
Sbjct: 3477 QDSPLSQPRSPAQILISLES----EERGELERILADLEEENRNLQAEYDRLKQ 3525



 Score =  306 bits (785), Expect = 6e-83
 Identities = 158/164 (96%), Positives = 159/164 (96%), Gaps = 2/164 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 3509 LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 3566

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 3567 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 3626

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1104
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N
Sbjct: 3627 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 3670



 Score =  100 bits (249), Expect = 8e-21
 Identities = 166/775 (21%), Positives = 312/775 (40%), Gaps = 89/775 (11%)

Query: 20   TELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKN 79
            T ++  L  ++Q++ +  +   D ED+ +     K     L+Q   +++ +I + +    
Sbjct: 2001 THVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRID-IIHSKKTAAL 2059

Query: 80   KTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM----------LKDSTQWLEAK 129
            +++    R  + + + ++  QW++V +  ++R+ + +            +K   QWL   
Sbjct: 2060 QSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLT-- 2117

Query: 130  EEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLR 189
             EAEQ L + +   E+W+   Y            K+L   + Q QT V   N    ++++
Sbjct: 2118 -EAEQFLRKTQIP-ENWEHAKYK--------WYLKELQDGIGQRQTVVRTLNATGEEIIQ 2167

Query: 190  DYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE 249
              S  D   +     ++N  W+ + K++S+R+  LEE   +L +F  DL +F+ WL EA+
Sbjct: 2168 QSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEAD 2227

Query: 250  TTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGS 309
              A++  +  ++++L E  + VK L+++    QG       +   L+E    +L S   S
Sbjct: 2228 NIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQG-------ILKQLNETGGPVLVSAPIS 2280

Query: 310  -DDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQE-------LLVWL 361
             ++   L+ +L   N +W ++ +     +  +EA      +L   L++       LL+WL
Sbjct: 2281 PEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWL 2340

Query: 362  Q--LKDDELSRQAPIGGDFP------AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVR 410
                   E+  Q    G F       AVQ KQ DV     +   L  ++P        + 
Sbjct: 2341 SPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLE 2400

Query: 411  IFLTEQPLEGLEKLYQEPRELPPE----------ERAQNVTRLLRKQAEEVNTEWEKLNL 460
               +E   + + +L QE R   P+             Q VT L+ +      T   KL +
Sbjct: 2401 DLSSE--WKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEM 2457

Query: 461  HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 520
             S+    ++    +  +   E TD L L     +VIK     VGDL  + + + + K KA
Sbjct: 2458 PSS-LMLEVPALADFNRAWTELTDWLSL---LDQVIKSQRVMVGDL--EDINEMIIKQKA 2511

Query: 521  LRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQL 578
               ++   +  +  +   A+ L           + T  +E +  +W  +Q  +++R +QL
Sbjct: 2512 TMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQL 2571

Query: 579  HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638
            +E  +D    S  +L    +       +  K+  +      T      K+TE  Q   DL
Sbjct: 2572 NEMLKD----STQWLEAKEEAEQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDL 2626

Query: 639  NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698
               + +          +   L L LL   +A D    H + +N        I   ++   
Sbjct: 2627 RQWQTNV--------DVANDLALKLLRDYSADDTRKVHMITENIN-ASWRSIHKRVSERE 2677

Query: 699  DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 748
              LE+ H  L   PL ++  L WL     T       T + R+L    G+  L K
Sbjct: 2678 AALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2732



 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 109/561 (19%), Positives = 234/561 (41%), Gaps = 59/561 (10%)

Query: 22   LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81
            L  W++ +D  +K +   +GD E + + + + +  + D++  +P L  +    Q +KN+ 
Sbjct: 1056 LKKWMAEVDVFLKEEWPALGDSEILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEA 1115

Query: 82   SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141
              + A  + T+ ++ +  QWD + + +  R++ L   L+ +    +   E  + + QA  
Sbjct: 1116 EPEFASRLETE-LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1174

Query: 142  KLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYS--ADDTRKV 199
            +         T D +QK + E K+  ++ +Q +  V +  +    ++      A +  K 
Sbjct: 1175 EYLERDFEYKTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKK 1234

Query: 200  HMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE----TTANVL 255
             + T   N  W  +  R++ +   LEE      +    LEK   WL E E    TT N+ 
Sbjct: 1235 ELETLTTNYQW--LCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIP 1292

Query: 256  QDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLL 315
              A   E + E    ++ LM+  +D   +I                     +G     L+
Sbjct: 1293 GGA---EEISEVLDSLENLMRHSEDNPNQIRILAQTL-------------TDGGVMDELI 1336

Query: 316  QRRLDNMNFKWSELRKKSLN----IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQ 371
               L+  N +W EL ++++     +   ++++ +  K LHL +QE L ++   D +L+  
Sbjct: 1337 NEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHL-IQESLTFI---DKQLA-- 1390

Query: 372  APIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 431
            A I     A Q   +  +            I S L +  I L E       K + + +E 
Sbjct: 1391 AYIADKVDAAQMPQEAQK------------IQSDLTSHEISLEEM------KKHNQGKE- 1431

Query: 432  PPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLR 491
               +R  +   + +K+ ++V+ ++ +L    A++++++ E+   L E++     L+ K  
Sbjct: 1432 -AAQRVLSQIDVAQKKLQDVSMKF-RLFQKPANFEQRLQESKMILDEVKMHLPALETKSV 1489

Query: 492  QAEVIKGSWQPVGDLL--IDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQL 549
            + EV++       +L   +  ++  +E V     +I   K+   +  +L  ++T L +  
Sbjct: 1490 EQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQ-KKQTENPKELDERVTALKLHY 1548

Query: 550  SPYNLSTLEDLNTRWKLLQVA 570
            +       E      K L+++
Sbjct: 1549 NELGAKVTERKQQLEKCLKLS 1569



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 70/339 (20%), Positives = 133/339 (39%), Gaps = 22/339 (6%)

Query: 3   SSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQ 62
           SSLM     L  +  A  E+  WL   +  +++Q  +  D+E + +     +  M DL  
Sbjct: 328 SSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTA 387

Query: 63  RRPQLEELITAAQNL--------KNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQ 114
            + ++  ++     L          +T  QE   ++  R E ++    E Q +L      
Sbjct: 388 HQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMD 447

Query: 115 L-NEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173
           L N+ LK+   WL   EE  +       K+E    GP  ++ +++++ + K L +DL Q 
Sbjct: 448 LQNQKLKELNDWLTKTEERTR-------KMEEEPLGP-DLEDLKRQVQQHKVLQEDLEQE 499

Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233
           Q  V+    + + +        T  +    + +   W +I +   +R   L++     Q+
Sbjct: 500 QVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQDILLKWQR 559

Query: 234 FPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYH 293
              +   F AWL+E E   N +     K     D   +   +++   L+ ++E       
Sbjct: 560 LTEEQCLFSAWLSEKEDAVNKIHTTGFK-----DQNEMLSSLQKLAVLKADLEKKKQSMG 614

Query: 294 NLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332
            L    Q +L +L+        +  LDN    W  L +K
Sbjct: 615 KLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQK 653



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 104/571 (18%), Positives = 222/571 (38%), Gaps = 46/571 (8%)

Query: 20   TELTDWLSLLDQVIKSQRVMV----GDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQ 75
            TEL  W++  + V++S    +    G+  D+ E   K  A  ++  ++  +L++   +AQ
Sbjct: 725  TELHSWITRSEAVLQSPEFAIFRKEGNFSDLKE---KVNAIEREKAEKFRKLQDASRSAQ 781

Query: 76   NLKNKTSNQEART-IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQ 134
             L  +  N+      I    E++ ++W E  + L  R   L E   +   +    ++ EQ
Sbjct: 782  ALVEQMVNEGVNADSIKQASEQLNSRWIEFCQLLSERLNWL-EYQNNIIAFYNQLQQLEQ 840

Query: 135  VLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSAD 194
            +   A   L+     P    AI+ ++   K     L   Q  ++     ++ L       
Sbjct: 841  MTTTAENWLKIQPTTPSEPTAIKSQLKICKDEVNRLSGLQPQIERLKIQSIALKEKGQGP 900

Query: 195  DTRKVHMITENINASWRSIHKRVSEREAALEETHRLL--QQFPLDLEKFLAWLTEAETTA 252
                   +       ++ +   V  RE  L+     L   ++   +     W+ ++ET  
Sbjct: 901  MFLDADFVA--FTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKL 958

Query: 253  NVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDA 312
            ++ Q +     ++E   G      + Q LQ  ++      + L    +++ +    S+ +
Sbjct: 959  SIPQLSVTDYEIMEQRLG------ELQALQSSLQEQQSGLYYLSTTVKEMSKKAP-SEIS 1011

Query: 313  VLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372
               Q   + +  +W +L  + +     LE   ++ +++   +Q L  W+   D  L  + 
Sbjct: 1012 RKYQSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEW 1071

Query: 373  PIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP 432
            P  GD   ++KQ    R    +++T +P + S              EG +K+     E  
Sbjct: 1072 PALGDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAE 1116

Query: 433  PEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQ 492
            PE  ++     L  + +E+NT+W+ +       +  +   LE+   LQ+   E+   + Q
Sbjct: 1117 PEFASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQ 1171

Query: 493  A--EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLS 550
            A  E ++  ++       D LQ  +E++K  + E    +  V  + +    +      ++
Sbjct: 1172 AEEEYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVA 1228

Query: 551  PYNL-STLEDLNTRWKLLQVAVEDRVRQLHE 580
               L   LE L T ++ L   +  + + L E
Sbjct: 1229 QEALKKELETLTTNYQWLCTRLNGKCKTLEE 1259



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 74/446 (16%), Positives = 186/446 (41%), Gaps = 40/446 (8%)

Query: 58   QDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNE 117
            + L + + ++E +I   + +  K   +  + +  +R+  ++  ++E+   +  R+QQL +
Sbjct: 1506 KSLSEVKSEVEMVIKTGRQIVQKKQTENPKEL-DERVTALKLHYNELGAKVTERKQQLEK 1564

Query: 118  MLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNV 177
             LK S +  +      + L     +L            +  ++   K   K++ + + ++
Sbjct: 1565 CLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHL 1624

Query: 178  DVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLD 237
                ++   L       +T     ++  +N++W ++  R  E    L E  + ++ F  +
Sbjct: 1625 KSITEVGEALKTVLGKKETLVEDKLSL-LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQN 1683

Query: 238  LEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDE 297
            ++    W+ +A+T    L D + K++  +    +K L  +  D++ ++++  D   NL  
Sbjct: 1684 VDHITKWIIQADT----LLDESEKKKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANLMA 1739

Query: 298  NSQKILRSLEGSDDAVLLQRRLDNMNFKWSELR------KKSLNIRSHLEASSDQWKRLH 351
            N         G     L++ ++  +N +++ +       K S+ ++   + +SD  K L 
Sbjct: 1740 N--------RGDHCRKLVEPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1791

Query: 352  LSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRI 411
                E+   + LK+++ ++              N+ +    +EL  +   +   +   R 
Sbjct: 1792 PLEAEIQQGVNLKEEDFNKD------------MNEDNEGTVKELLQRGDNLQQRITDER- 1838

Query: 412  FLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDE 471
                + ++  ++L Q       + R+Q      RK+A E++ +W +    + D  + +D+
Sbjct: 1839 --KREEIKIKQQLLQTKHNALKDLRSQR-----RKKALEISHQWYQYKRQADDLLKCLDD 1891

Query: 472  TLERLQELQEATDELDLKLRQAEVIK 497
              ++L  L E  DE  +K    E+ K
Sbjct: 1892 IEKKLASLPEPRDERKIKEIDRELQK 1917



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 96/533 (18%), Positives = 216/533 (40%), Gaps = 75/533 (14%)

Query: 12   LADFNRAWTELTDWL----SLLDQVIKSQRVMVGDLEDINEMI----------IKQKATM 57
            L  FN  W EL +       LL+Q I+S +     L  I E +          I  K   
Sbjct: 1340 LETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQESLTFIDKQLAAYIADKVDA 1399

Query: 58   QDLEQRRPQLEELITA----AQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQ 113
              + Q   +++  +T+     + +K     +EA        +R+ +Q D  Q+ LQ+   
Sbjct: 1400 AQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAA-------QRVLSQIDVAQKKLQDVSM 1452

Query: 114  QLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173
            +   + +    + +  +E++ +L + +  L + +      + +Q ++     L K L + 
Sbjct: 1453 KFR-LFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSLSEV 1511

Query: 174  QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233
            ++ V++      ++++    ++ +++      +   +  +  +V+ER+  LE+  +L ++
Sbjct: 1512 KSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNELGAKVTERKQQLEKCLKLSRK 1571

Query: 234  FPLDLEKFLAWL--TEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDV 291
               ++     WL  T+ E T     +        E + G K   K+ +  +  +++ T+V
Sbjct: 1572 MRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWG-KATQKEIEKQKVHLKSITEV 1630

Query: 292  YHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLH 351
                     + L+++ G  +  L++ +L  +N  W  +  ++    + L       +   
Sbjct: 1631 --------GEALKTVLGKKE-TLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFD 1681

Query: 352  LSLQELLVWLQLKD---DELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 408
             ++  +  W+   D   DE  ++ P        Q++ DV +  K EL    P + ST + 
Sbjct: 1682 QNVDHITKWIIQADTLLDESEKKKP--------QQKEDVLKRLKAELNDIRPKVDSTRDQ 1733

Query: 409  VRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLR--------KQAEEVNTEWEKL-- 458
                +  +  +   KL  EP+      R   ++  ++        K+ E+ N++ +KL  
Sbjct: 1734 AANLMANRG-DHCRKLV-EPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1791

Query: 459  ----------NLHSADWQRKIDETLE-RLQELQEATDELDLKL---RQAEVIK 497
                      NL   D+ + ++E  E  ++EL +  D L  ++   R+ E IK
Sbjct: 1792 PLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQQRITDERKREEIK 1844



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%)

Query: 286 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 340
           E H  ++H +  + Q  +   +G +     + R  +  +  +     S   RS     HL
Sbjct: 259 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 318

Query: 341 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 388
           EA  D+              R   +L+E+L WL   +D L  Q  I  D   V+ Q   H
Sbjct: 319 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 378

Query: 389 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 448
             +  +L   +  + + L+          L G  KL ++      EE        +++Q 
Sbjct: 379 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 420

Query: 449 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 503
             +N+ WE L + S + Q  +   L     ++L+EL +   + + + R+ E      +P+
Sbjct: 421 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 475

Query: 504 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 559
           G  L D L+  +++ K L+ +   L++    VN L   +  +      +  + LE+    
Sbjct: 476 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 531

Query: 560 LNTRWKLLQVAVEDR 574
           L  RW  +    EDR
Sbjct: 532 LGDRWANICRWTEDR 546


>gi|5032309 dystrophin Dp140b isoform [Homo sapiens]
          Length = 1243

 Score = 1908 bits (4943), Expect = 0.0
 Identities = 970/1073 (90%), Positives = 988/1073 (92%), Gaps = 52/1073 (4%)

Query: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60
            MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL
Sbjct: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60

Query: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120
            EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK
Sbjct: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120

Query: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
            DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA
Sbjct: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180

Query: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240
            NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK
Sbjct: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240

Query: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300
            FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ
Sbjct: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300

Query: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360
            KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW
Sbjct: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360

Query: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420
            LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG
Sbjct: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420

Query: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480
            LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ
Sbjct: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480

Query: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540
            EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR
Sbjct: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540

Query: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600
            QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP
Sbjct: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600

Query: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660
            WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC
Sbjct: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660

Query: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720
            LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN
Sbjct: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720

Query: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780
            WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD
Sbjct: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780

Query: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840
            SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR
Sbjct: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840

Query: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900
            VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC
Sbjct: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900

Query: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNL---------- 950
            TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET +          
Sbjct: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960

Query: 951  ------QAEYDRLKQQHEHKG-------------LSPLPSPPEMMP-------------- 977
                  Q  +D    + EH               L+   SP E +               
Sbjct: 961  APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020

Query: 978  -----TSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQ 1025
                 + P+SP    +  E+    + +G LE  +  LE+ N+ L+++  RL+Q
Sbjct: 1021 QDSPLSQPRSPAQILISLES----EERGELERILADLEEENRNLQAEYDRLKQ 1069



 Score =  365 bits (936), Expect = e-100
 Identities = 188/193 (97%), Positives = 189/193 (97%), Gaps = 2/193 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 1053 LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1110

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 1111 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1170

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAME 1120
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAME
Sbjct: 1171 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAME 1230

Query: 1121 SLVSVMTDEEGAE 1133
            SLVSVMTDEEGAE
Sbjct: 1231 SLVSVMTDEEGAE 1243


>gi|5032293 dystrophin Dp140 isoform [Homo sapiens]
          Length = 1225

 Score = 1908 bits (4943), Expect = 0.0
 Identities = 970/1073 (90%), Positives = 988/1073 (92%), Gaps = 52/1073 (4%)

Query: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60
            MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL
Sbjct: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60

Query: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120
            EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK
Sbjct: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120

Query: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
            DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA
Sbjct: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180

Query: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240
            NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK
Sbjct: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240

Query: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300
            FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ
Sbjct: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300

Query: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360
            KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW
Sbjct: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360

Query: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420
            LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG
Sbjct: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420

Query: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480
            LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ
Sbjct: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480

Query: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540
            EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR
Sbjct: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540

Query: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600
            QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP
Sbjct: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600

Query: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660
            WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC
Sbjct: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660

Query: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720
            LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN
Sbjct: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720

Query: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780
            WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD
Sbjct: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780

Query: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840
            SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR
Sbjct: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840

Query: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900
            VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC
Sbjct: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900

Query: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNL---------- 950
            TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET +          
Sbjct: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960

Query: 951  ------QAEYDRLKQQHEHKG-------------LSPLPSPPEMMP-------------- 977
                  Q  +D    + EH               L+   SP E +               
Sbjct: 961  APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020

Query: 978  -----TSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQ 1025
                 + P+SP    +  E+    + +G LE  +  LE+ N+ L+++  RL+Q
Sbjct: 1021 QDSPLSQPRSPAQILISLES----EERGELERILADLEEENRNLQAEYDRLKQ 1069



 Score =  306 bits (785), Expect = 6e-83
 Identities = 158/164 (96%), Positives = 159/164 (96%), Gaps = 2/164 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 1053 LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1110

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 1111 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1170

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1104
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N
Sbjct: 1171 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 1214


>gi|5032285 dystrophin Dp427l isoform [Homo sapiens]
          Length = 3562

 Score = 1908 bits (4943), Expect = 0.0
 Identities = 970/1073 (90%), Positives = 988/1073 (92%), Gaps = 52/1073 (4%)

Query: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60
            MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL
Sbjct: 2338 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 2397

Query: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120
            EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK
Sbjct: 2398 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 2457

Query: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
            DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA
Sbjct: 2458 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2517

Query: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240
            NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK
Sbjct: 2518 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 2577

Query: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300
            FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ
Sbjct: 2578 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 2637

Query: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360
            KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW
Sbjct: 2638 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 2697

Query: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420
            LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG
Sbjct: 2698 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 2757

Query: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480
            LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ
Sbjct: 2758 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 2817

Query: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540
            EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR
Sbjct: 2818 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 2877

Query: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600
            QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP
Sbjct: 2878 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 2937

Query: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660
            WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC
Sbjct: 2938 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 2997

Query: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720
            LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN
Sbjct: 2998 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 3057

Query: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780
            WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD
Sbjct: 3058 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 3117

Query: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840
            SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR
Sbjct: 3118 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 3177

Query: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900
            VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC
Sbjct: 3178 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 3237

Query: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNL---------- 950
            TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET +          
Sbjct: 3238 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 3297

Query: 951  ------QAEYDRLKQQHEHKG-------------LSPLPSPPEMMP-------------- 977
                  Q  +D    + EH               L+   SP E +               
Sbjct: 3298 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 3357

Query: 978  -----TSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQ 1025
                 + P+SP    +  E+    + +G LE  +  LE+ N+ L+++  RL+Q
Sbjct: 3358 QDSPLSQPRSPAQILISLES----EERGELERILADLEEENRNLQAEYDRLKQ 3406



 Score =  306 bits (785), Expect = 6e-83
 Identities = 158/164 (96%), Positives = 159/164 (96%), Gaps = 2/164 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 3390 LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 3447

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 3448 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 3507

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1104
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N
Sbjct: 3508 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 3551



 Score =  100 bits (249), Expect = 8e-21
 Identities = 166/775 (21%), Positives = 312/775 (40%), Gaps = 89/775 (11%)

Query: 20   TELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKN 79
            T ++  L  ++Q++ +  +   D ED+ +     K     L+Q   +++ +I + +    
Sbjct: 1882 THVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRID-IIHSKKTAAL 1940

Query: 80   KTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM----------LKDSTQWLEAK 129
            +++    R  + + + ++  QW++V +  ++R+ + +            +K   QWL   
Sbjct: 1941 QSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLT-- 1998

Query: 130  EEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLR 189
             EAEQ L + +   E+W+   Y            K+L   + Q QT V   N    ++++
Sbjct: 1999 -EAEQFLRKTQIP-ENWEHAKYK--------WYLKELQDGIGQRQTVVRTLNATGEEIIQ 2048

Query: 190  DYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE 249
              S  D   +     ++N  W+ + K++S+R+  LEE   +L +F  DL +F+ WL EA+
Sbjct: 2049 QSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEAD 2108

Query: 250  TTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGS 309
              A++  +  ++++L E  + VK L+++    QG       +   L+E    +L S   S
Sbjct: 2109 NIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQG-------ILKQLNETGGPVLVSAPIS 2161

Query: 310  -DDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQE-------LLVWL 361
             ++   L+ +L   N +W ++ +     +  +EA      +L   L++       LL+WL
Sbjct: 2162 PEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWL 2221

Query: 362  Q--LKDDELSRQAPIGGDFP------AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVR 410
                   E+  Q    G F       AVQ KQ DV     +   L  ++P        + 
Sbjct: 2222 SPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLE 2281

Query: 411  IFLTEQPLEGLEKLYQEPRELPPE----------ERAQNVTRLLRKQAEEVNTEWEKLNL 460
               +E   + + +L QE R   P+             Q VT L+ +      T   KL +
Sbjct: 2282 DLSSE--WKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEM 2338

Query: 461  HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 520
             S+    ++    +  +   E TD L L     +VIK     VGDL  + + + + K KA
Sbjct: 2339 PSS-LMLEVPALADFNRAWTELTDWLSL---LDQVIKSQRVMVGDL--EDINEMIIKQKA 2392

Query: 521  LRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQL 578
               ++   +  +  +   A+ L           + T  +E +  +W  +Q  +++R +QL
Sbjct: 2393 TMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQL 2452

Query: 579  HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638
            +E  +D    S  +L    +       +  K+  +      T      K+TE  Q   DL
Sbjct: 2453 NEMLKD----STQWLEAKEEAEQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDL 2507

Query: 639  NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698
               + +          +   L L LL   +A D    H + +N        I   ++   
Sbjct: 2508 RQWQTNV--------DVANDLALKLLRDYSADDTRKVHMITENIN-ASWRSIHKRVSERE 2558

Query: 699  DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 748
              LE+ H  L   PL ++  L WL     T       T + R+L    G+  L K
Sbjct: 2559 AALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2613



 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 109/561 (19%), Positives = 234/561 (41%), Gaps = 59/561 (10%)

Query: 22   LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81
            L  W++ +D  +K +   +GD E + + + + +  + D++  +P L  +    Q +KN+ 
Sbjct: 937  LKKWMAEVDVFLKEEWPALGDSEILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEA 996

Query: 82   SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141
              + A  + T+ ++ +  QWD + + +  R++ L   L+ +    +   E  + + QA  
Sbjct: 997  EPEFASRLETE-LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1055

Query: 142  KLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYS--ADDTRKV 199
            +         T D +QK + E K+  ++ +Q +  V +  +    ++      A +  K 
Sbjct: 1056 EYLERDFEYKTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKK 1115

Query: 200  HMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE----TTANVL 255
             + T   N  W  +  R++ +   LEE      +    LEK   WL E E    TT N+ 
Sbjct: 1116 ELETLTTNYQW--LCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIP 1173

Query: 256  QDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLL 315
              A   E + E    ++ LM+  +D   +I                     +G     L+
Sbjct: 1174 GGA---EEISEVLDSLENLMRHSEDNPNQIRILAQTL-------------TDGGVMDELI 1217

Query: 316  QRRLDNMNFKWSELRKKSLN----IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQ 371
               L+  N +W EL ++++     +   ++++ +  K LHL +QE L ++   D +L+  
Sbjct: 1218 NEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHL-IQESLTFI---DKQLA-- 1271

Query: 372  APIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 431
            A I     A Q   +  +            I S L +  I L E       K + + +E 
Sbjct: 1272 AYIADKVDAAQMPQEAQK------------IQSDLTSHEISLEEM------KKHNQGKE- 1312

Query: 432  PPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLR 491
               +R  +   + +K+ ++V+ ++ +L    A++++++ E+   L E++     L+ K  
Sbjct: 1313 -AAQRVLSQIDVAQKKLQDVSMKF-RLFQKPANFEQRLQESKMILDEVKMHLPALETKSV 1370

Query: 492  QAEVIKGSWQPVGDLL--IDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQL 549
            + EV++       +L   +  ++  +E V     +I   K+   +  +L  ++T L +  
Sbjct: 1371 EQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQ-KKQTENPKELDERVTALKLHY 1429

Query: 550  SPYNLSTLEDLNTRWKLLQVA 570
            +       E      K L+++
Sbjct: 1430 NELGAKVTERKQQLEKCLKLS 1450



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 70/339 (20%), Positives = 133/339 (39%), Gaps = 22/339 (6%)

Query: 3   SSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQ 62
           SSLM     L  +  A  E+  WL   +  +++Q  +  D+E + +     +  M DL  
Sbjct: 209 SSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTA 268

Query: 63  RRPQLEELITAAQNL--------KNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQ 114
            + ++  ++     L          +T  QE   ++  R E ++    E Q +L      
Sbjct: 269 HQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMD 328

Query: 115 L-NEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173
           L N+ LK+   WL   EE  +       K+E    GP  ++ +++++ + K L +DL Q 
Sbjct: 329 LQNQKLKELNDWLTKTEERTR-------KMEEEPLGP-DLEDLKRQVQQHKVLQEDLEQE 380

Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233
           Q  V+    + + +        T  +    + +   W +I +   +R   L++     Q+
Sbjct: 381 QVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQDILLKWQR 440

Query: 234 FPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYH 293
              +   F AWL+E E   N +     K     D   +   +++   L+ ++E       
Sbjct: 441 LTEEQCLFSAWLSEKEDAVNKIHTTGFK-----DQNEMLSSLQKLAVLKADLEKKKQSMG 495

Query: 294 NLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332
            L    Q +L +L+        +  LDN    W  L +K
Sbjct: 496 KLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQK 534



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 104/571 (18%), Positives = 222/571 (38%), Gaps = 46/571 (8%)

Query: 20   TELTDWLSLLDQVIKSQRVMV----GDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQ 75
            TEL  W++  + V++S    +    G+  D+ E   K  A  ++  ++  +L++   +AQ
Sbjct: 606  TELHSWITRSEAVLQSPEFAIFRKEGNFSDLKE---KVNAIEREKAEKFRKLQDASRSAQ 662

Query: 76   NLKNKTSNQEART-IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQ 134
             L  +  N+      I    E++ ++W E  + L  R   L E   +   +    ++ EQ
Sbjct: 663  ALVEQMVNEGVNADSIKQASEQLNSRWIEFCQLLSERLNWL-EYQNNIIAFYNQLQQLEQ 721

Query: 135  VLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSAD 194
            +   A   L+     P    AI+ ++   K     L   Q  ++     ++ L       
Sbjct: 722  MTTTAENWLKIQPTTPSEPTAIKSQLKICKDEVNRLSGLQPQIERLKIQSIALKEKGQGP 781

Query: 195  DTRKVHMITENINASWRSIHKRVSEREAALEETHRLL--QQFPLDLEKFLAWLTEAETTA 252
                   +       ++ +   V  RE  L+     L   ++   +     W+ ++ET  
Sbjct: 782  MFLDADFVA--FTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKL 839

Query: 253  NVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDA 312
            ++ Q +     ++E   G      + Q LQ  ++      + L    +++ +    S+ +
Sbjct: 840  SIPQLSVTDYEIMEQRLG------ELQALQSSLQEQQSGLYYLSTTVKEMSKKAP-SEIS 892

Query: 313  VLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372
               Q   + +  +W +L  + +     LE   ++ +++   +Q L  W+   D  L  + 
Sbjct: 893  RKYQSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEW 952

Query: 373  PIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP 432
            P  GD   ++KQ    R    +++T +P + S              EG +K+     E  
Sbjct: 953  PALGDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAE 997

Query: 433  PEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQ 492
            PE  ++     L  + +E+NT+W+ +       +  +   LE+   LQ+   E+   + Q
Sbjct: 998  PEFASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQ 1052

Query: 493  A--EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLS 550
            A  E ++  ++       D LQ  +E++K  + E    +  V  + +    +      ++
Sbjct: 1053 AEEEYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVA 1109

Query: 551  PYNL-STLEDLNTRWKLLQVAVEDRVRQLHE 580
               L   LE L T ++ L   +  + + L E
Sbjct: 1110 QEALKKELETLTTNYQWLCTRLNGKCKTLEE 1140



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 74/446 (16%), Positives = 186/446 (41%), Gaps = 40/446 (8%)

Query: 58   QDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNE 117
            + L + + ++E +I   + +  K   +  + +  +R+  ++  ++E+   +  R+QQL +
Sbjct: 1387 KSLSEVKSEVEMVIKTGRQIVQKKQTENPKEL-DERVTALKLHYNELGAKVTERKQQLEK 1445

Query: 118  MLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNV 177
             LK S +  +      + L     +L            +  ++   K   K++ + + ++
Sbjct: 1446 CLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHL 1505

Query: 178  DVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLD 237
                ++   L       +T     ++  +N++W ++  R  E    L E  + ++ F  +
Sbjct: 1506 KSITEVGEALKTVLGKKETLVEDKLSL-LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQN 1564

Query: 238  LEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDE 297
            ++    W+ +A+T    L D + K++  +    +K L  +  D++ ++++  D   NL  
Sbjct: 1565 VDHITKWIIQADT----LLDESEKKKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANLMA 1620

Query: 298  NSQKILRSLEGSDDAVLLQRRLDNMNFKWSELR------KKSLNIRSHLEASSDQWKRLH 351
            N         G     L++ ++  +N +++ +       K S+ ++   + +SD  K L 
Sbjct: 1621 N--------RGDHCRKLVEPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1672

Query: 352  LSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRI 411
                E+   + LK+++ ++              N+ +    +EL  +   +   +   R 
Sbjct: 1673 PLEAEIQQGVNLKEEDFNKD------------MNEDNEGTVKELLQRGDNLQQRITDER- 1719

Query: 412  FLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDE 471
                + ++  ++L Q       + R+Q      RK+A E++ +W +    + D  + +D+
Sbjct: 1720 --KREEIKIKQQLLQTKHNALKDLRSQR-----RKKALEISHQWYQYKRQADDLLKCLDD 1772

Query: 472  TLERLQELQEATDELDLKLRQAEVIK 497
              ++L  L E  DE  +K    E+ K
Sbjct: 1773 IEKKLASLPEPRDERKIKEIDRELQK 1798



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 96/533 (18%), Positives = 216/533 (40%), Gaps = 75/533 (14%)

Query: 12   LADFNRAWTELTDWL----SLLDQVIKSQRVMVGDLEDINEMI----------IKQKATM 57
            L  FN  W EL +       LL+Q I+S +     L  I E +          I  K   
Sbjct: 1221 LETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQESLTFIDKQLAAYIADKVDA 1280

Query: 58   QDLEQRRPQLEELITA----AQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQ 113
              + Q   +++  +T+     + +K     +EA        +R+ +Q D  Q+ LQ+   
Sbjct: 1281 AQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAA-------QRVLSQIDVAQKKLQDVSM 1333

Query: 114  QLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173
            +   + +    + +  +E++ +L + +  L + +      + +Q ++     L K L + 
Sbjct: 1334 KFR-LFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSLSEV 1392

Query: 174  QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233
            ++ V++      ++++    ++ +++      +   +  +  +V+ER+  LE+  +L ++
Sbjct: 1393 KSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNELGAKVTERKQQLEKCLKLSRK 1452

Query: 234  FPLDLEKFLAWL--TEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDV 291
               ++     WL  T+ E T     +        E + G K   K+ +  +  +++ T+V
Sbjct: 1453 MRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWG-KATQKEIEKQKVHLKSITEV 1511

Query: 292  YHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLH 351
                     + L+++ G  +  L++ +L  +N  W  +  ++    + L       +   
Sbjct: 1512 --------GEALKTVLGKKE-TLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFD 1562

Query: 352  LSLQELLVWLQLKD---DELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 408
             ++  +  W+   D   DE  ++ P        Q++ DV +  K EL    P + ST + 
Sbjct: 1563 QNVDHITKWIIQADTLLDESEKKKP--------QQKEDVLKRLKAELNDIRPKVDSTRDQ 1614

Query: 409  VRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLR--------KQAEEVNTEWEKL-- 458
                +  +  +   KL  EP+      R   ++  ++        K+ E+ N++ +KL  
Sbjct: 1615 AANLMANRG-DHCRKLV-EPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1672

Query: 459  ----------NLHSADWQRKIDETLE-RLQELQEATDELDLKL---RQAEVIK 497
                      NL   D+ + ++E  E  ++EL +  D L  ++   R+ E IK
Sbjct: 1673 PLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQQRITDERKREEIK 1725



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%)

Query: 286 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 340
           E H  ++H +  + Q  +   +G +     + R  +  +  +     S   RS     HL
Sbjct: 140 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 199

Query: 341 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 388
           EA  D+              R   +L+E+L WL   +D L  Q  I  D   V+ Q   H
Sbjct: 200 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 259

Query: 389 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 448
             +  +L   +  + + L+          L G  KL ++      EE        +++Q 
Sbjct: 260 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 301

Query: 449 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 503
             +N+ WE L + S + Q  +   L     ++L+EL +   + + + R+ E      +P+
Sbjct: 302 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 356

Query: 504 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 559
           G  L D L+  +++ K L+ +   L++    VN L   +  +      +  + LE+    
Sbjct: 357 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 412

Query: 560 LNTRWKLLQVAVEDR 574
           L  RW  +    EDR
Sbjct: 413 LGDRWANICRWTEDR 427


>gi|5032283 dystrophin Dp427m isoform [Homo sapiens]
          Length = 3685

 Score = 1908 bits (4943), Expect = 0.0
 Identities = 970/1073 (90%), Positives = 988/1073 (92%), Gaps = 52/1073 (4%)

Query: 1    MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60
            MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL
Sbjct: 2461 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 2520

Query: 61   EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120
            EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK
Sbjct: 2521 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 2580

Query: 121  DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
            DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA
Sbjct: 2581 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2640

Query: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240
            NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK
Sbjct: 2641 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 2700

Query: 241  FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300
            FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ
Sbjct: 2701 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 2760

Query: 301  KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360
            KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW
Sbjct: 2761 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 2820

Query: 361  LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420
            LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG
Sbjct: 2821 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 2880

Query: 421  LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480
            LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ
Sbjct: 2881 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 2940

Query: 481  EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540
            EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR
Sbjct: 2941 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 3000

Query: 541  QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600
            QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP
Sbjct: 3001 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 3060

Query: 601  WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660
            WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC
Sbjct: 3061 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 3120

Query: 661  LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720
            LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN
Sbjct: 3121 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 3180

Query: 721  WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780
            WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD
Sbjct: 3181 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 3240

Query: 781  SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840
            SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR
Sbjct: 3241 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 3300

Query: 841  VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900
            VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC
Sbjct: 3301 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 3360

Query: 901  TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNL---------- 950
            TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET +          
Sbjct: 3361 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 3420

Query: 951  ------QAEYDRLKQQHEHKG-------------LSPLPSPPEMMP-------------- 977
                  Q  +D    + EH               L+   SP E +               
Sbjct: 3421 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 3480

Query: 978  -----TSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQ 1025
                 + P+SP    +  E+    + +G LE  +  LE+ N+ L+++  RL+Q
Sbjct: 3481 QDSPLSQPRSPAQILISLES----EERGELERILADLEEENRNLQAEYDRLKQ 3529



 Score =  306 bits (785), Expect = 6e-83
 Identities = 158/164 (96%), Positives = 159/164 (96%), Gaps = 2/164 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 3513 LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 3570

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 3571 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 3630

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1104
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N
Sbjct: 3631 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 3674



 Score =  100 bits (249), Expect = 8e-21
 Identities = 166/775 (21%), Positives = 312/775 (40%), Gaps = 89/775 (11%)

Query: 20   TELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKN 79
            T ++  L  ++Q++ +  +   D ED+ +     K     L+Q   +++ +I + +    
Sbjct: 2005 THVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRID-IIHSKKTAAL 2063

Query: 80   KTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM----------LKDSTQWLEAK 129
            +++    R  + + + ++  QW++V +  ++R+ + +            +K   QWL   
Sbjct: 2064 QSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLT-- 2121

Query: 130  EEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLR 189
             EAEQ L + +   E+W+   Y            K+L   + Q QT V   N    ++++
Sbjct: 2122 -EAEQFLRKTQIP-ENWEHAKYK--------WYLKELQDGIGQRQTVVRTLNATGEEIIQ 2171

Query: 190  DYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE 249
              S  D   +     ++N  W+ + K++S+R+  LEE   +L +F  DL +F+ WL EA+
Sbjct: 2172 QSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEAD 2231

Query: 250  TTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGS 309
              A++  +  ++++L E  + VK L+++    QG       +   L+E    +L S   S
Sbjct: 2232 NIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQG-------ILKQLNETGGPVLVSAPIS 2284

Query: 310  -DDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQE-------LLVWL 361
             ++   L+ +L   N +W ++ +     +  +EA      +L   L++       LL+WL
Sbjct: 2285 PEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWL 2344

Query: 362  Q--LKDDELSRQAPIGGDFP------AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVR 410
                   E+  Q    G F       AVQ KQ DV     +   L  ++P        + 
Sbjct: 2345 SPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLE 2404

Query: 411  IFLTEQPLEGLEKLYQEPRELPPE----------ERAQNVTRLLRKQAEEVNTEWEKLNL 460
               +E   + + +L QE R   P+             Q VT L+ +      T   KL +
Sbjct: 2405 DLSSE--WKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEM 2461

Query: 461  HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 520
             S+    ++    +  +   E TD L L     +VIK     VGDL  + + + + K KA
Sbjct: 2462 PSS-LMLEVPALADFNRAWTELTDWLSL---LDQVIKSQRVMVGDL--EDINEMIIKQKA 2515

Query: 521  LRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQL 578
               ++   +  +  +   A+ L           + T  +E +  +W  +Q  +++R +QL
Sbjct: 2516 TMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQL 2575

Query: 579  HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638
            +E  +D    S  +L    +       +  K+  +      T      K+TE  Q   DL
Sbjct: 2576 NEMLKD----STQWLEAKEEAEQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDL 2630

Query: 639  NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698
               + +          +   L L LL   +A D    H + +N        I   ++   
Sbjct: 2631 RQWQTNV--------DVANDLALKLLRDYSADDTRKVHMITENIN-ASWRSIHKRVSERE 2681

Query: 699  DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 748
              LE+ H  L   PL ++  L WL     T       T + R+L    G+  L K
Sbjct: 2682 AALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2736



 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 109/561 (19%), Positives = 234/561 (41%), Gaps = 59/561 (10%)

Query: 22   LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81
            L  W++ +D  +K +   +GD E + + + + +  + D++  +P L  +    Q +KN+ 
Sbjct: 1060 LKKWMAEVDVFLKEEWPALGDSEILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEA 1119

Query: 82   SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141
              + A  + T+ ++ +  QWD + + +  R++ L   L+ +    +   E  + + QA  
Sbjct: 1120 EPEFASRLETE-LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1178

Query: 142  KLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYS--ADDTRKV 199
            +         T D +QK + E K+  ++ +Q +  V +  +    ++      A +  K 
Sbjct: 1179 EYLERDFEYKTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKK 1238

Query: 200  HMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE----TTANVL 255
             + T   N  W  +  R++ +   LEE      +    LEK   WL E E    TT N+ 
Sbjct: 1239 ELETLTTNYQW--LCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIP 1296

Query: 256  QDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLL 315
              A   E + E    ++ LM+  +D   +I                     +G     L+
Sbjct: 1297 GGA---EEISEVLDSLENLMRHSEDNPNQIRILAQTL-------------TDGGVMDELI 1340

Query: 316  QRRLDNMNFKWSELRKKSLN----IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQ 371
               L+  N +W EL ++++     +   ++++ +  K LHL +QE L ++   D +L+  
Sbjct: 1341 NEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHL-IQESLTFI---DKQLA-- 1394

Query: 372  APIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 431
            A I     A Q   +  +            I S L +  I L E       K + + +E 
Sbjct: 1395 AYIADKVDAAQMPQEAQK------------IQSDLTSHEISLEEM------KKHNQGKE- 1435

Query: 432  PPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLR 491
               +R  +   + +K+ ++V+ ++ +L    A++++++ E+   L E++     L+ K  
Sbjct: 1436 -AAQRVLSQIDVAQKKLQDVSMKF-RLFQKPANFEQRLQESKMILDEVKMHLPALETKSV 1493

Query: 492  QAEVIKGSWQPVGDLL--IDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQL 549
            + EV++       +L   +  ++  +E V     +I   K+   +  +L  ++T L +  
Sbjct: 1494 EQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQ-KKQTENPKELDERVTALKLHY 1552

Query: 550  SPYNLSTLEDLNTRWKLLQVA 570
            +       E      K L+++
Sbjct: 1553 NELGAKVTERKQQLEKCLKLS 1573



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 70/339 (20%), Positives = 133/339 (39%), Gaps = 22/339 (6%)

Query: 3   SSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQ 62
           SSLM     L  +  A  E+  WL   +  +++Q  +  D+E + +     +  M DL  
Sbjct: 332 SSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTA 391

Query: 63  RRPQLEELITAAQNL--------KNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQ 114
            + ++  ++     L          +T  QE   ++  R E ++    E Q +L      
Sbjct: 392 HQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMD 451

Query: 115 L-NEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173
           L N+ LK+   WL   EE  +       K+E    GP  ++ +++++ + K L +DL Q 
Sbjct: 452 LQNQKLKELNDWLTKTEERTR-------KMEEEPLGP-DLEDLKRQVQQHKVLQEDLEQE 503

Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233
           Q  V+    + + +        T  +    + +   W +I +   +R   L++     Q+
Sbjct: 504 QVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQDILLKWQR 563

Query: 234 FPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYH 293
              +   F AWL+E E   N +     K     D   +   +++   L+ ++E       
Sbjct: 564 LTEEQCLFSAWLSEKEDAVNKIHTTGFK-----DQNEMLSSLQKLAVLKADLEKKKQSMG 618

Query: 294 NLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332
            L    Q +L +L+        +  LDN    W  L +K
Sbjct: 619 KLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQK 657



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 104/571 (18%), Positives = 222/571 (38%), Gaps = 46/571 (8%)

Query: 20   TELTDWLSLLDQVIKSQRVMV----GDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQ 75
            TEL  W++  + V++S    +    G+  D+ E   K  A  ++  ++  +L++   +AQ
Sbjct: 729  TELHSWITRSEAVLQSPEFAIFRKEGNFSDLKE---KVNAIEREKAEKFRKLQDASRSAQ 785

Query: 76   NLKNKTSNQEART-IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQ 134
             L  +  N+      I    E++ ++W E  + L  R   L E   +   +    ++ EQ
Sbjct: 786  ALVEQMVNEGVNADSIKQASEQLNSRWIEFCQLLSERLNWL-EYQNNIIAFYNQLQQLEQ 844

Query: 135  VLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSAD 194
            +   A   L+     P    AI+ ++   K     L   Q  ++     ++ L       
Sbjct: 845  MTTTAENWLKIQPTTPSEPTAIKSQLKICKDEVNRLSGLQPQIERLKIQSIALKEKGQGP 904

Query: 195  DTRKVHMITENINASWRSIHKRVSEREAALEETHRLL--QQFPLDLEKFLAWLTEAETTA 252
                   +       ++ +   V  RE  L+     L   ++   +     W+ ++ET  
Sbjct: 905  MFLDADFVA--FTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKL 962

Query: 253  NVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDA 312
            ++ Q +     ++E   G      + Q LQ  ++      + L    +++ +    S+ +
Sbjct: 963  SIPQLSVTDYEIMEQRLG------ELQALQSSLQEQQSGLYYLSTTVKEMSKKAP-SEIS 1015

Query: 313  VLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372
               Q   + +  +W +L  + +     LE   ++ +++   +Q L  W+   D  L  + 
Sbjct: 1016 RKYQSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEW 1075

Query: 373  PIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP 432
            P  GD   ++KQ    R    +++T +P + S              EG +K+     E  
Sbjct: 1076 PALGDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAE 1120

Query: 433  PEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQ 492
            PE  ++     L  + +E+NT+W+ +       +  +   LE+   LQ+   E+   + Q
Sbjct: 1121 PEFASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQ 1175

Query: 493  A--EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLS 550
            A  E ++  ++       D LQ  +E++K  + E    +  V  + +    +      ++
Sbjct: 1176 AEEEYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVA 1232

Query: 551  PYNL-STLEDLNTRWKLLQVAVEDRVRQLHE 580
               L   LE L T ++ L   +  + + L E
Sbjct: 1233 QEALKKELETLTTNYQWLCTRLNGKCKTLEE 1263



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 74/446 (16%), Positives = 186/446 (41%), Gaps = 40/446 (8%)

Query: 58   QDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNE 117
            + L + + ++E +I   + +  K   +  + +  +R+  ++  ++E+   +  R+QQL +
Sbjct: 1510 KSLSEVKSEVEMVIKTGRQIVQKKQTENPKEL-DERVTALKLHYNELGAKVTERKQQLEK 1568

Query: 118  MLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNV 177
             LK S +  +      + L     +L            +  ++   K   K++ + + ++
Sbjct: 1569 CLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHL 1628

Query: 178  DVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLD 237
                ++   L       +T     ++  +N++W ++  R  E    L E  + ++ F  +
Sbjct: 1629 KSITEVGEALKTVLGKKETLVEDKLSL-LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQN 1687

Query: 238  LEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDE 297
            ++    W+ +A+T    L D + K++  +    +K L  +  D++ ++++  D   NL  
Sbjct: 1688 VDHITKWIIQADT----LLDESEKKKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANLMA 1743

Query: 298  NSQKILRSLEGSDDAVLLQRRLDNMNFKWSELR------KKSLNIRSHLEASSDQWKRLH 351
            N         G     L++ ++  +N +++ +       K S+ ++   + +SD  K L 
Sbjct: 1744 N--------RGDHCRKLVEPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1795

Query: 352  LSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRI 411
                E+   + LK+++ ++              N+ +    +EL  +   +   +   R 
Sbjct: 1796 PLEAEIQQGVNLKEEDFNKD------------MNEDNEGTVKELLQRGDNLQQRITDER- 1842

Query: 412  FLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDE 471
                + ++  ++L Q       + R+Q      RK+A E++ +W +    + D  + +D+
Sbjct: 1843 --KREEIKIKQQLLQTKHNALKDLRSQR-----RKKALEISHQWYQYKRQADDLLKCLDD 1895

Query: 472  TLERLQELQEATDELDLKLRQAEVIK 497
              ++L  L E  DE  +K    E+ K
Sbjct: 1896 IEKKLASLPEPRDERKIKEIDRELQK 1921



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 96/533 (18%), Positives = 216/533 (40%), Gaps = 75/533 (14%)

Query: 12   LADFNRAWTELTDWL----SLLDQVIKSQRVMVGDLEDINEMI----------IKQKATM 57
            L  FN  W EL +       LL+Q I+S +     L  I E +          I  K   
Sbjct: 1344 LETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQESLTFIDKQLAAYIADKVDA 1403

Query: 58   QDLEQRRPQLEELITA----AQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQ 113
              + Q   +++  +T+     + +K     +EA        +R+ +Q D  Q+ LQ+   
Sbjct: 1404 AQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAA-------QRVLSQIDVAQKKLQDVSM 1456

Query: 114  QLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173
            +   + +    + +  +E++ +L + +  L + +      + +Q ++     L K L + 
Sbjct: 1457 KFR-LFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSLSEV 1515

Query: 174  QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233
            ++ V++      ++++    ++ +++      +   +  +  +V+ER+  LE+  +L ++
Sbjct: 1516 KSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNELGAKVTERKQQLEKCLKLSRK 1575

Query: 234  FPLDLEKFLAWL--TEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDV 291
               ++     WL  T+ E T     +        E + G K   K+ +  +  +++ T+V
Sbjct: 1576 MRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWG-KATQKEIEKQKVHLKSITEV 1634

Query: 292  YHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLH 351
                     + L+++ G  +  L++ +L  +N  W  +  ++    + L       +   
Sbjct: 1635 --------GEALKTVLGKKE-TLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFD 1685

Query: 352  LSLQELLVWLQLKD---DELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 408
             ++  +  W+   D   DE  ++ P        Q++ DV +  K EL    P + ST + 
Sbjct: 1686 QNVDHITKWIIQADTLLDESEKKKP--------QQKEDVLKRLKAELNDIRPKVDSTRDQ 1737

Query: 409  VRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLR--------KQAEEVNTEWEKL-- 458
                +  +  +   KL  EP+      R   ++  ++        K+ E+ N++ +KL  
Sbjct: 1738 AANLMANRG-DHCRKLV-EPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1795

Query: 459  ----------NLHSADWQRKIDETLE-RLQELQEATDELDLKL---RQAEVIK 497
                      NL   D+ + ++E  E  ++EL +  D L  ++   R+ E IK
Sbjct: 1796 PLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQQRITDERKREEIK 1848



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%)

Query: 286 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 340
           E H  ++H +  + Q  +   +G +     + R  +  +  +     S   RS     HL
Sbjct: 263 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 322

Query: 341 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 388
           EA  D+              R   +L+E+L WL   +D L  Q  I  D   V+ Q   H
Sbjct: 323 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 382

Query: 389 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 448
             +  +L   +  + + L+          L G  KL ++      EE        +++Q 
Sbjct: 383 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 424

Query: 449 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 503
             +N+ WE L + S + Q  +   L     ++L+EL +   + + + R+ E      +P+
Sbjct: 425 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 479

Query: 504 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 559
           G  L D L+  +++ K L+ +   L++    VN L   +  +      +  + LE+    
Sbjct: 480 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 535

Query: 560 LNTRWKLLQVAVEDR 574
           L  RW  +    EDR
Sbjct: 536 LGDRWANICRWTEDR 550


>gi|5032295 dystrophin Dp116 isoform [Homo sapiens]
          Length = 956

 Score = 1363 bits (3527), Expect = 0.0
 Identities = 691/795 (86%), Positives = 710/795 (89%), Gaps = 52/795 (6%)

Query: 279  QDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 338
            +DLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS
Sbjct: 10   KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69

Query: 339  HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 398
            HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK
Sbjct: 70   HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 129

Query: 399  EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 458
            EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL
Sbjct: 130  EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 189

Query: 459  NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 518
            NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV
Sbjct: 190  NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 249

Query: 519  KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 578
            KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL
Sbjct: 250  KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309

Query: 579  HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638
            HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL
Sbjct: 310  HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 369

Query: 639  NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698
            NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY
Sbjct: 370  NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 429

Query: 699  DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 758
            DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL
Sbjct: 430  DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 489

Query: 759  FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 818
            FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA
Sbjct: 490  FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 549

Query: 819  ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 878
            ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ
Sbjct: 550  ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 609

Query: 879  SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 938
            SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ
Sbjct: 610  SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 669

Query: 939  TVLEGDNMETNL----------------QAEYDRLKQQHEHKG-------------LSPL 969
            TVLEGDNMET +                Q  +D    + EH               L+  
Sbjct: 670  TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 729

Query: 970  PSPPEMMP-------------------TSPQSPRDAELIAEAKLLRQHKGRLEARMQILE 1010
             SP E +                    + P+SP    +  E+    + +G LE  +  LE
Sbjct: 730  ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLES----EERGELERILADLE 785

Query: 1011 DHNKQLESQLHRLRQ 1025
            + N+ L+++  RL+Q
Sbjct: 786  EENRNLQAEYDRLKQ 800



 Score =  306 bits (785), Expect = 6e-83
 Identities = 158/164 (96%), Positives = 159/164 (96%), Gaps = 2/164 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 784  LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 841

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 842  RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 901

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1104
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N
Sbjct: 902  VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 945



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 53/235 (22%), Positives = 99/235 (42%), Gaps = 33/235 (14%)

Query: 21  ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ-------------- 66
           EL  WL L D  +  Q  + GD   + +     +A  ++L+ + P               
Sbjct: 87  ELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTE 146

Query: 67  -----LEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD 121
                LE+L    + L  +   Q    ++  + E +  +W+++  H  + +++++E L+ 
Sbjct: 147 QPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLER 206

Query: 122 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
             +  EA +E +  L QA     SW+  G   +D++Q  + + K L  ++   + NV   
Sbjct: 207 LQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHV 266

Query: 181 NDLALKL------LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHR 229
           NDLA +L      L  Y+           E++N  W+ +   V +R   L E HR
Sbjct: 267 NDLARQLTTLGIQLSPYNLSTL-------EDLNTRWKLLQVAVEDRVRQLHEAHR 314



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 70/329 (21%), Positives = 138/329 (41%), Gaps = 52/329 (15%)

Query: 168 KDLR-QWQTNVDVANDL---ALKLLRDYS-ADDTRKVHMITENINASWRSIHKRVSEREA 222
           KDL+ + + + DV ++L   + K+LR    +DD   +    +N+N  W  + K+     +
Sbjct: 10  KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69

Query: 223 ALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQ 282
            LE +    ++  L L++ L WL   +       + +R+  +  D   V++     +  +
Sbjct: 70  HLEASSDQWKRLHLSLQELLVWLQLKD------DELSRQAPIGGDFPAVQKQNDVHRAFK 123

Query: 283 GEIEAHTDVYHNLDENSQKIL--RSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN--IRS 338
            E++    V  +  E  +  L  + LEG +      R L        E R +++   +R 
Sbjct: 124 RELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP------PEERAQNVTRLLRK 177

Query: 339 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 398
             E  + +W++L+L   +   W +  D+ L R          +Q+  D     + +LK +
Sbjct: 178 QAEEVNTEWEKLNLHSAD---WQRKIDETLER-------LQELQEATD-----ELDLKLR 222

Query: 399 E-PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP-EERAQNVTRLLRK---------- 446
           +  VI  + + V   L +   + LEK+     E+ P +E   +V  L R+          
Sbjct: 223 QAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSP 282

Query: 447 ----QAEEVNTEWEKLNLHSADWQRKIDE 471
                 E++NT W+ L +   D  R++ E
Sbjct: 283 YNLSTLEDLNTRWKLLQVAVEDRVRQLHE 311


>gi|110611228 utrophin [Homo sapiens]
          Length = 3433

 Score = 1170 bits (3027), Expect = 0.0
 Identities = 565/944 (59%), Positives = 728/944 (77%), Gaps = 5/944 (0%)

Query: 8    EVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQL 67
            E+   AD ++  TEL DWL L+DQ++KS  V VGD+E+IN+ + + K T  DLEQR PQL
Sbjct: 2224 EISIPADLDKTITELADWLVLIDQMLKSNIVTVGDVEEINKTVSRMKITKADLEQRHPQL 2283

Query: 68   EELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLE 127
            + + T AQNLKNK S+ + RT IT+++ER++NQWD  Q  ++ R+QQL +M+ DS QW +
Sbjct: 2284 DYVFTLAQNLKNKASSSDMRTAITEKLERVKNQWDGTQHGVELRQQQLEDMIIDSLQWDD 2343

Query: 128  AKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKL 187
             +EE E+++ +  A+L   ++     D + K+I++ + L ++L      V   +++  KL
Sbjct: 2344 HREETEELMRKYEARLYILQQARR--DPLTKQISDNQILLQELGPGDGIVMAFDNVLQKL 2401

Query: 188  LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTE 247
            L +Y +DDTR V   TE +  SW ++ + +++R+ ALE   R +Q    DLE FL W+ E
Sbjct: 2402 LEEYGSDDTRNVKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQE 2461

Query: 248  AETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLE 307
            AETT NVL DA+ +E  L+DS   +EL +Q QD+Q EI+AH D++ ++D N QK++++L 
Sbjct: 2462 AETTVNVLVDASHRENALQDSILARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALG 2521

Query: 308  GSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDE 367
             S++A +LQ RLD+MN +W++L+ KS +IR+HLEAS+++W RL +SL+EL+ WL +KD+E
Sbjct: 2522 NSEEATMLQHRLDDMNQRWNDLKAKSASIRAHLEASAEKWNRLLMSLEELIKWLNMKDEE 2581

Query: 368  LSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLE---KL 424
            L +Q PIGGD PA+Q Q D  +A +RELK KE  +++ ++  R+FL +QP+E  E   + 
Sbjct: 2582 LKKQMPIGGDVPALQLQYDHCKALRRELKEKEYSVLNAVDQARVFLADQPIEAPEEPRRN 2641

Query: 425  YQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATD 484
             Q   EL PEERAQ + + +RKQ+ EV  +WE LN  +++WQ+++D+ LE+L++LQ A D
Sbjct: 2642 LQSKTELTPEERAQKIAKAMRKQSSEVKEKWESLNAVTSNWQKQVDKALEKLRDLQGAMD 2701

Query: 485  ELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTT 544
            +LD  +++AE ++  W+PVGDLLIDSLQDH+EK+ A R EIAP+   V  VNDL+ QL+ 
Sbjct: 2702 DLDADMKEAESVRNGWKPVGDLLIDSLQDHIEKIMAFREEIAPINFKVKTVNDLSSQLSP 2761

Query: 545  LGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERA 604
            L +  S      L+DLN RWKLLQV+V+DR++QL EAHRDFGP+SQHFLSTSVQ PW+R+
Sbjct: 2762 LDLHPSLKMSRQLDDLNMRWKLLQVSVDDRLKQLQEAHRDFGPSSQHFLSTSVQLPWQRS 2821

Query: 605  ISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLL 664
            IS NKVPYYINH+TQTTCWDHPKMTEL+QSLADLNNVRFSAYRTA+K+RRLQKALCLDLL
Sbjct: 2822 ISHNKVPYYINHQTQTTCWDHPKMTELFQSLADLNNVRFSAYRTAIKIRRLQKALCLDLL 2881

Query: 665  SLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLN 724
             LS   +   QH L QNDQ + +  +INCLTT YD LEQ H +LVNVPLCVDMCLNWLLN
Sbjct: 2882 ELSTTNEIFKQHKLNQNDQLLSVPDVINCLTTTYDGLEQMHKDLVNVPLCVDMCLNWLLN 2941

Query: 725  VYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQI 784
            VYDTGRTG+IRV S K G++SL K  LE+KYRYLFK+VA  T  CDQR+LGLLLHD+IQI
Sbjct: 2942 VYDTGRTGKIRVQSLKIGLMSLSKGLLEEKYRYLFKEVAGPTEMCDQRQLGLLLHDAIQI 3001

Query: 785  PRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAA 844
            PRQLGEVA+FGGSNIEPSVRSCFQ  NNKPEI    F+DWM LEPQSMVWLPVLHRVAAA
Sbjct: 3002 PRQLGEVAAFGGSNIEPSVRSCFQQNNNKPEISVKEFIDWMHLEPQSMVWLPVLHRVAAA 3061

Query: 845  ETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTT 904
            ETAKHQAKCNICKECPI+GFRYRSLKHFNYD+CQSCFFSGR AKGHK+HYPMVEYC PTT
Sbjct: 3062 ETAKHQAKCNICKECPIVGFRYRSLKHFNYDVCQSCFFSGRTAKGHKLHYPMVEYCIPTT 3121

Query: 905  SGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET 948
            SGEDVRDF KVLKNKFR+K+YFAKHPR+GYLPVQTVLEGDN+ET
Sbjct: 3122 SGEDVRDFTKVLKNKFRSKKYFAKHPRLGYLPVQTVLEGDNLET 3165



 Score =  166 bits (419), Expect = 2e-40
 Identities = 104/211 (49%), Positives = 137/211 (64%), Gaps = 19/211 (9%)

Query: 893  HYPMVEYCTPTTSGEDV----RDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET 948
            H  + +YC  T  GE      +  A++LK+  R +R        G L  + + + +  + 
Sbjct: 3226 HALIQQYCQ-TLGGESPVSQPQSPAQILKSVEREER--------GELE-RIIADLEEEQR 3275

Query: 949  NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 1008
            NLQ EY++LK QH  +GL P+ SPPE + +   +  D+ELIAEAKLLRQHKGRLEARMQI
Sbjct: 3276 NLQVEYEQLKDQHLRRGL-PVGSPPESIISPHHTSEDSELIAEAKLLRQHKGRLEARMQI 3334

Query: 1009 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 1068
            LEDHNKQLESQLHRLRQLLEQP++++++NG    SP  S Q S  S  +     G Q   
Sbjct: 3335 LEDHNKQLESQLHRLRQLLEQPESDSRINGV---SPWASPQHSALSYSLDPDASGPQFHQ 3391

Query: 1069 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPS 1099
            + G EDLL+PP DTST L EVMEQ++++FPS
Sbjct: 3392 AAG-EDLLAPPHDTSTDLTEVMEQIHSTFPS 3421



 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 117/589 (19%), Positives = 260/589 (44%), Gaps = 68/589 (11%)

Query: 7    LEVPALADFNRAWTELTDWLSLLDQVIKSQRVM-VGDLEDINEMIIKQKATMQDLEQRRP 65
            +++ A   F+    EL +W+      I++  +     ++D +EM  K KA  ++  +R P
Sbjct: 684  VDIEAKKKFDAISAELLNWILKWKTAIQTTEIKEYMKMQDTSEMKKKLKALEKEQRERIP 743

Query: 66   QLEELITAAQNLKNKTSNQEARTI-ITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQ 124
            + +EL    Q L  +   +   T  I + +E++ ++W  V +HL++  +++ ++ +D   
Sbjct: 744  RADELNQTGQILVEQMGKEGLPTEEIKNVLEKVSSEWKNVSQHLEDLERKI-QLQEDINA 802

Query: 125  WLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAK----DLRQWQTNVDVA 180
            + +  +E E+V+       E W +     ++ ++ +   K   +    +L      +++A
Sbjct: 803  YFKQLDELEKVIKTK----EEWVKHTSISESSRQSLPSLKDSCQRELTNLLGLHPKIEMA 858

Query: 181  NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALE------------ETH 228
                  L+   SA D   V    ++    ++++ + V +R+  LE            ET 
Sbjct: 859  RASCSALMSQPSAPDF--VQRGFDSFLGRYQAVQEAVEDRQQHLENELKGQPGHAYLETL 916

Query: 229  RLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAH 288
            + L+    D E       +A+ + NVL D  + E+ L++ K + E++          E  
Sbjct: 917  KTLKDVLNDSEN------KAQVSLNVLNDLAKVEKALQEKKTLDEIL----------ENQ 960

Query: 289  TDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELR---KKSLNIRSHLEASSD 345
                H L E ++ + +++   D   L ++  D++  KW++L+    K L++   +  +  
Sbjct: 961  KPALHKLAEETKALEKNVH-PDVEKLYKQEFDDVQGKWNKLKVLVSKDLHLLEEIALTLR 1019

Query: 346  QWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMST 405
             ++     +++   W+    D L +Q    GD   +Q+Q D   AF  E++T E   +  
Sbjct: 1020 AFEADSTVIEK---WMDGVKDFLMKQQAAQGDDAGLQRQLDQCSAFVNEIETIES-SLKN 1075

Query: 406  LETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADW 465
            ++ +   L   P+ G+ K + + R    + + + +++ +  Q   ++   EK    +A+ 
Sbjct: 1076 MKEIETNLRSGPVAGI-KTWVQTRLGDYQTQLEKLSKEIATQKSRLSESQEK----AANL 1130

Query: 466  QRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEI 525
            ++ + E  E + + +E   E D + +  E ++ + + +     D LQ  + +VK L+  I
Sbjct: 1131 KKDLAEMQEWMTQAEEEYLERDFEYKSPEELESAVEEMKRAKEDVLQKEV-RVKILKDNI 1189

Query: 526  APLKENVSHVNDLARQLTT-LGIQLSPYNL---------STLEDLNTRW 564
              L    + V    ++LT+ L + L  Y L          TLE++ + W
Sbjct: 1190 KLL---AAKVPSGGQELTSELNVVLENYQLLCNRIRGKCHTLEEVWSCW 1235



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 116/614 (18%), Positives = 250/614 (40%), Gaps = 71/614 (11%)

Query: 12  LADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELI 71
           L  +  A  E+  WL   +   + Q  +  D+E++ +     +A M +L   +  +  ++
Sbjct: 311 LDSYQIALEEVLTWLLSAEDTFQEQDDISDDVEEVKDQFATHEAFMMELTAHQSSVGSVL 370

Query: 72  TAAQNLKNK-TSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQ------ 124
            A   L  + T + E    I +++  +  +W+ ++    +R+ +L+++L +  +      
Sbjct: 371 QAGNQLITQGTLSDEEEFEIQEQMTLLNARWEALRVESMDRQSRLHDVLMELQKKQLQQL 430

Query: 125 --WLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVAND 182
             WL   EE  Q       K+E+       V ++QK + E K L  DL   Q  V+    
Sbjct: 431 SAWLTLTEERIQ-------KMETCPLDD-DVKSLQKLLEEHKSLQSDLEAEQVKVNSLTH 482

Query: 183 LALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFL 242
           + + +  +     T  +    + +   W ++ +   ER   L+E + L Q+   +     
Sbjct: 483 MVVIVDENSGESATAILEDQLQKLGERWTAVCRWTEERWNRLQEINILWQELLEEQCLLK 542

Query: 243 AWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKI 302
           AWLTE E   N +Q +  K     D K +   +++   L+ ++E        L E  Q +
Sbjct: 543 AWLTEKEEALNKVQTSNFK-----DQKELSVSVRRLAILKEDMEMKRQTLDQLSEIGQDV 597

Query: 303 LRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQ 362
            + L+ S  +  +    + +  +W  L ++  +  + +  +  +     +  ++LL  ++
Sbjct: 598 GQLLDNSKASKKINSDSEELTQRWDSLVQRLEDSSNQVTQAVAKLGMSQIPQKDLLETVR 657

Query: 363 LKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTL---------------- 406
           +++  +++++      P   K+  +H     E K K   I + L                
Sbjct: 658 VREQAITKKSKQELPPPPPPKKRQIH--VDIEAKKKFDAISAELLNWILKWKTAIQTTEI 715

Query: 407 -ETVRIFLTEQPLEGLEKLYQEPRELPPEERAQN---------------VTRLLRKQAEE 450
            E +++  T +  + L+ L +E RE  P     N                T  ++   E+
Sbjct: 716 KEYMKMQDTSEMKKKLKALEKEQRERIPRADELNQTGQILVEQMGKEGLPTEEIKNVLEK 775

Query: 451 VNTEWEKLNLHSADWQRK------IDETLERLQELQEATDELDLKLRQAEVIKGSWQPVG 504
           V++EW+ ++ H  D +RK      I+   ++L EL++     +  ++   + + S Q + 
Sbjct: 776 VSSEWKNVSQHLEDLERKIQLQEDINAYFKQLDELEKVIKTKEEWVKHTSISESSRQSLP 835

Query: 505 DLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRW 564
            L  DS Q  L  +  L  +I   + + S +  +++      +Q         +    R+
Sbjct: 836 SLK-DSCQRELTNLLGLHPKIEMARASCSAL--MSQPSAPDFVQRG------FDSFLGRY 886

Query: 565 KLLQVAVEDRVRQL 578
           + +Q AVEDR + L
Sbjct: 887 QAVQEAVEDRQQHL 900



 Score = 70.9 bits (172), Expect = 7e-12
 Identities = 80/381 (20%), Positives = 155/381 (40%), Gaps = 47/381 (12%)

Query: 218 SEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQ 277
           +E  + + E    L  + + LE+ L WL  AE T     D +      +D + VK+    
Sbjct: 298 AETPSTVTEVDMDLDSYQIALEEVLTWLLSAEDTFQEQDDIS------DDVEEVKDQFAT 351

Query: 278 WQDLQGEIEAH-TDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNI 336
            +    E+ AH + V   L   +Q I +     ++   +Q ++  +N +W  LR +S++ 
Sbjct: 352 HEAFMMELTAHQSSVGSVLQAGNQLITQGTLSDEEEFEIQEQMTLLNARWEALRVESMDR 411

Query: 337 RSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQ--APIGGDFPAVQKQNDVHRAFKRE 394
           +S L     + ++  L  Q+L  WL L ++ + +    P+  D  ++QK  + H++ + +
Sbjct: 412 QSRLHDVLMELQKKQL--QQLSAWLTLTEERIQKMETCPLDDDVKSLQKLLEEHKSLQSD 469

Query: 395 LKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTE 454
           L+ ++  + S    V I                      E   ++ T +L  Q +++   
Sbjct: 470 LEAEQVKVNSLTHMVVIV--------------------DENSGESATAILEDQLQKLGER 509

Query: 455 WEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDH 514
           W  +   + +   ++ E     QEL E    L   L + E      + +  +   + +D 
Sbjct: 510 WTAVCRWTEERWNRLQEINILWQELLEEQCLLKAWLTEKE------EALNKVQTSNFKDQ 563

Query: 515 LEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQL---------SPYNLSTLEDLNTRWK 565
            E   ++R  +A LKE++        QL+ +G  +         S    S  E+L  RW 
Sbjct: 564 KELSVSVR-RLAILKEDMEMKRQTLDQLSEIGQDVGQLLDNSKASKKINSDSEELTQRWD 622

Query: 566 LLQVAVEDRVRQLHEAHRDFG 586
            L   +ED   Q+ +A    G
Sbjct: 623 SLVQRLEDSSNQVTQAVAKLG 643



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 114/635 (17%), Positives = 254/635 (40%), Gaps = 79/635 (12%)

Query: 3    SSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQR--------------VMVGDLE---- 44
            SS  L  P LA+ NR + +++  +     +I  +               V   DLE    
Sbjct: 1721 SSRELVEPKLAELNRNFEKVSQHIKSAKLLIAQEPLYQCLVTTETFETGVPFSDLEKLEN 1780

Query: 45   DINEMI------IKQKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQ 98
            DI  M+      ++     + +++   Q+EE++   + + ++      +  I  ++  + 
Sbjct: 1781 DIENMLKFVEKHLESSDEDEKMDEESAQIEEVLQRGEEMLHQPMEDNKKEKIRLQLLLLH 1840

Query: 99   NQWDEVQE-HLQNRRQ-QLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAI 156
             ++++++   +Q R+  QL   ++ S    +   E  ++L      +E     P    AI
Sbjct: 1841 TRYNKIKAIPIQQRKMGQLASGIRSSLLPTDYLVEINKIL-LCMDDVELSLNVPELNTAI 1899

Query: 157  QKKIT----ETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRS 212
             +  +      K +   L +    + V ++    ++ + S  +  ++      +NA W  
Sbjct: 1900 YEDFSFQEDSLKNIKDQLDKLGEQIAVIHEKQPDVILEASGPEAIQIRDTLTQLNAKWDR 1959

Query: 213  IHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVK 272
            I++  S+R+   +      +QF  DL     W+TEAE    +L D       L+    ++
Sbjct: 1960 INRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWITEAE---ELLVDTCAPGGSLD----LE 2012

Query: 273  ELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332
            +     Q+L+  I +H   +  L+     I++ L  +D +  L+ +L  +N +W  +  +
Sbjct: 2013 KARIHQQELEVGISSHQPSFAALNRTGDGIVQKLSQADGS-FLKEKLAGLNQRWDAIVAE 2071

Query: 333  SLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA--PIGGDFPAVQ---KQNDV 387
              + +  L+  S Q  +    L E++ WL   +  + +++   +G +   ++   ++ +V
Sbjct: 2072 VKDRQPRLKGESKQVMKYRHQLDEIICWLTKAEHAMQKRSTTELGENLQELRDLTQEMEV 2131

Query: 388  HRAFKRELKTKEPVIMS--------------TLETVRIF---LTEQPLEGLEKLYQEPRE 430
            H    + L   E  ++S              +L TV +    +  +    L++  QEP  
Sbjct: 2132 HAEKLKWLNRTELEMLSDKSLSLPERDKISESLRTVNMTWNKICREVPTTLKECIQEPSS 2191

Query: 431  LPPEERA--QNVTR-LLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELD 487
            +     A   NV + +L   A ++  +  + +  S      +D+T+  L +     D++ 
Sbjct: 2192 VSQTRIAAHPNVQKVVLVSSASDIPVQSHRTSEISI--PADLDKTITELADWLVLIDQM- 2248

Query: 488  LKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGI 547
                    +K +   VGD  ++ +   + ++K  + ++      + +V  LA+ L     
Sbjct: 2249 --------LKSNIVTVGD--VEEINKTVSRMKITKADLEQRHPQLDYVFTLAQNLKNKAS 2298

Query: 548  QLSPYNLST--LEDLNTRWKLLQVAVEDRVRQLHE 580
                    T  LE +  +W   Q  VE R +QL +
Sbjct: 2299 SSDMRTAITEKLERVKNQWDGTQHGVELRQQQLED 2333



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 100/541 (18%), Positives = 198/541 (36%), Gaps = 92/541 (17%)

Query: 90   ITDRIERIQNQWDEVQEHLQNRR----------QQLNEMLKDSTQWLEAKEEAEQVLGQA 139
            I D + ++  +WD +     +R+          +Q +  L D TQW+    EAE++L   
Sbjct: 1946 IRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWIT---EAEELLVDT 2002

Query: 140  RAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKV 199
             A   S          ++K     ++L   +   Q +    N     +++  S  D   +
Sbjct: 2003 CAPGGSLD--------LEKARIHQQELEVGISSHQPSFAALNRTGDGIVQKLSQADGSFL 2054

Query: 200  HMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDAT 259
                  +N  W +I   V +R+  L+   + + ++   L++ + WLT+AE        A 
Sbjct: 2055 KEKLAGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICWLTKAE-------HAM 2107

Query: 260  RKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRR- 318
            +K    E  + ++EL    +DL  E+E H +    L+    ++L     SD ++ L  R 
Sbjct: 2108 QKRSTTELGENLQEL----RDLTQEMEVHAEKLKWLNRTELEML-----SDKSLSLPERD 2158

Query: 319  -----LDNMNFKWSELRKK------------------------------------SLNIR 337
                 L  +N  W+++ ++                                     + ++
Sbjct: 2159 KISESLRTVNMTWNKICREVPTTLKECIQEPSSVSQTRIAAHPNVQKVVLVSSASDIPVQ 2218

Query: 338  SHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKT 397
            SH  +       L  ++ EL  WL L D  L       GD   + K     +  K +L+ 
Sbjct: 2219 SHRTSEISIPADLDKTITELADWLVLIDQMLKSNIVTVGDVEEINKTVSRMKITKADLEQ 2278

Query: 398  KEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPE--ERAQNVTRLLRKQAEEV---N 452
            + P +       +    +     +     E  E      +  Q+   L ++Q E++   +
Sbjct: 2279 RHPQLDYVFTLAQNLKNKASSSDMRTAITEKLERVKNQWDGTQHGVELRQQQLEDMIIDS 2338

Query: 453  TEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQ 512
             +W+     + +  RK +  L  LQ  Q   D L  ++   +++     P GD ++ +  
Sbjct: 2339 LQWDDHREETEELMRKYEARLYILQ--QARRDPLTKQISDNQILLQELGP-GDGIVMAFD 2395

Query: 513  DHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVE 572
            + L+K+    G      ++  +V +    L T  I L          L   W+ +Q +  
Sbjct: 2396 NVLQKLLEEYG-----SDDTRNVKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRR 2450

Query: 573  D 573
            D
Sbjct: 2451 D 2451



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 95/519 (18%), Positives = 212/519 (40%), Gaps = 71/519 (13%)

Query: 17   RAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITA--- 73
            R WTE  DW + L        +  G++  I+  + + +A + ++E++    +E I     
Sbjct: 1637 RTWTE--DWCNTLMNHQNQLEIFDGNVAHISTWLYQAEALLDEIEKKPTSKQEEIVKRLV 1694

Query: 74   ---------AQNLKNKT------SNQEARTIITDRIERIQNQWDEVQEHLQNRR-----Q 113
                      +N++++           +R ++  ++  +   +++V +H+++ +     +
Sbjct: 1695 SELDDANLQVENVRDQALILMNARGSSSRELVEPKLAELNRNFEKVSQHIKSAKLLIAQE 1754

Query: 114  QLNEMLKDSTQW--------LEAKE-EAEQVLGQARAKLESWKEGPYTVDAIQKKITETK 164
             L + L  +  +        LE  E + E +L      LES  E    +D    +I E  
Sbjct: 1755 PLYQCLVTTETFETGVPFSDLEKLENDIENMLKFVEKHLESSDEDE-KMDEESAQIEEVL 1813

Query: 165  QLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAAL 224
            Q  +++       +    + L+LL  ++  +  K   I +      R + +  S   ++L
Sbjct: 1814 QRGEEMLHQPMEDNKKEKIRLQLLLLHTRYNKIKAIPIQQ------RKMGQLASGIRSSL 1867

Query: 225  EETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGE 284
              T  L++     + K L  + + E + NV +  T    + ED    ++ +K  +D   +
Sbjct: 1868 LPTDYLVE-----INKILLCMDDVELSLNVPELNTA---IYEDFSFQEDSLKNIKDQLDK 1919

Query: 285  IEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASS 344
            +     V H   E    ++    G + A+ ++  L  +N KW  + +   + +   + + 
Sbjct: 1920 LGEQIAVIH---EKQPDVILEASGPE-AIQIRDTLTQLNAKWDRINRMYSDRKGCFDRAM 1975

Query: 345  DQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV-----QKQNDV-----HRAFKRE 394
            ++W++ H  L +L  W+   ++ L      GG          Q++ +V       +F   
Sbjct: 1976 EEWRQFHCDLNDLTQWITEAEELLVDTCAPGGSLDLEKARIHQQELEVGISSHQPSFAAL 2035

Query: 395  LKTKEPVIMSTLETVRIFLTEQPLEGL----EKLYQEPRELPPEERAQNVTRL-LRKQAE 449
             +T + ++    +    FL E+ L GL    + +  E ++  P  + ++   +  R Q +
Sbjct: 2036 NRTGDGIVQKLSQADGSFLKEK-LAGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLD 2094

Query: 450  EVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDL 488
            E+   W     H+   +R   E  E LQEL++ T E+++
Sbjct: 2095 EIIC-WLTKAEHAMQ-KRSTTELGENLQELRDLTQEMEV 2131



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 106/574 (18%), Positives = 231/574 (40%), Gaps = 67/574 (11%)

Query: 22   LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81
            L++WLS  +  +  +    G L D++  I   K  ++DLE+R+  L  +  ++  L+N  
Sbjct: 1556 LSEWLSATETELVQKSTSEGLLGDLDTEISWAKNVLKDLEKRKADLNTITESSAALQNLI 1615

Query: 82   SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141
               E   I+ +R+  +   W  V+   ++     N ++    Q         ++     A
Sbjct: 1616 EGSE--PILEERLCVLNAGWSRVRTWTED---WCNTLMNHQNQL--------EIFDGNVA 1662

Query: 142  KLESW-KEGPYTVDAIQKKITE-----TKQLAKDLRQWQTNVDVANDLALKLLRDYSADD 195
             + +W  +    +D I+KK T       K+L  +L      V+   D AL L+    +  
Sbjct: 1663 HISTWLYQAEALLDEIEKKPTSKQEEIVKRLVSELDDANLQVENVRDQALILMNARGSSS 1722

Query: 196  TRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWL--TEAETTAN 253
               V      +N ++  + + +  + A L      L Q  +  E F   +  ++ E   N
Sbjct: 1723 RELVEPKLAELNRNFEKVSQHI--KSAKLLIAQEPLYQCLVTTETFETGVPFSDLEKLEN 1780

Query: 254  VLQDATR-KERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDA 312
             +++  +  E+ LE S   +++ ++   ++  ++   ++ H   E+++K    L+     
Sbjct: 1781 DIENMLKFVEKHLESSDEDEKMDEESAQIEEVLQRGEEMLHQPMEDNKKEKIRLQ----L 1836

Query: 313  VLLQRRLDNMN---FKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELS 369
            +LL  R + +     +  ++ + +  IRS L   +D    ++  L      L + D ELS
Sbjct: 1837 LLLHTRYNKIKAIPIQQRKMGQLASGIRSSL-LPTDYLVEINKIL------LCMDDVELS 1889

Query: 370  RQAPIGGDFPAVQKQNDVHRAF---KRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQ 426
               P        +    ++  F   +  LK  +  +    E + +   +QP   LE    
Sbjct: 1890 LNVP--------ELNTAIYEDFSFQEDSLKNIKDQLDKLGEQIAVIHEKQPDVILEASGP 1941

Query: 427  EPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDEL 486
            E  +             +R    ++N +W+++N   +D +   D  +E  ++     ++L
Sbjct: 1942 EAIQ-------------IRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDL 1988

Query: 487  DLKLRQA-EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVND-LARQLTT 544
               + +A E++  +  P G L ++  + H ++++       P    ++   D + ++L+ 
Sbjct: 1989 TQWITEAEELLVDTCAPGGSLDLEKARIHQQELEVGISSHQPSFAALNRTGDGIVQKLSQ 2048

Query: 545  LGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 578
                   +    L  LN RW  +   V+DR  +L
Sbjct: 2049 AD---GSFLKEKLAGLNQRWDAIVAEVKDRQPRL 2079



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 108/599 (18%), Positives = 232/599 (38%), Gaps = 104/599 (17%)

Query: 19   WTEL-------TDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELI 71
            W EL       T WL+ L++ +KS  V+    + +NE +   ++ ++     R Q+ EL 
Sbjct: 1235 WIELLHYLDLETTWLNTLEERMKSTEVLPEKTDAVNEALESLESVLRHPADNRTQIREL- 1293

Query: 72   TAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEE 131
               Q L +     +   II++++E   ++++++    ++++  L + L    Q L   ++
Sbjct: 1294 --GQTLIDGGILDD---IISEKLEAFNSRYEDLSHLAESKQISLEKQL----QVLRETDQ 1344

Query: 132  AEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDY 191
              QVL ++  +L+  +   Y  D I     +  Q+ ++ ++ Q  +  A++L L+ LR  
Sbjct: 1345 MLQVLQESLGELDK-QLTTYLTDRI-----DAFQVPQEAQKIQAEIS-AHELTLEELRR- 1396

Query: 192  SADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETT 251
                    +M ++ +     S   R +   + ++   R L++     + F       +  
Sbjct: 1397 --------NMRSQPLT----SPESRTARGGSQMDVLQRKLREVSTKFQLF-------QKP 1437

Query: 252  ANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTD----VYHNLDENSQKI----- 302
            AN  Q     +R+L+  K    ++         I+ H D    +Y  L E   ++     
Sbjct: 1438 ANFEQRMLDCKRVLDGVKAELHVLDVKDVDPDVIQTHLDKCMKLYKTLSEVKLEVETVIK 1497

Query: 303  ----LRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELL 358
                +   + +D+   +  +L ++   +++L  +    +  LE +S   +++      L 
Sbjct: 1498 TGRHIVQKQQTDNPKGMDEQLTSLKVLYNDLGAQVTEGKQDLERASQLARKMKKEAASLS 1557

Query: 359  VWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPL 418
             WL   + EL +++   G    +  +    +   ++L+ ++  + +  E+      +  +
Sbjct: 1558 EWLSATETELVQKSTSEGLLGDLDTEISWAKNVLKDLEKRKADLNTITESSAAL--QNLI 1615

Query: 419  EGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQE 478
            EG E + +E              RL       +N  W ++   + DW   +     +L+ 
Sbjct: 1616 EGSEPILEE--------------RLC-----VLNAGWSRVRTWTEDWCNTLMNHQNQLEI 1656

Query: 479  LQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDL 538
                   +   L QAE               +L D +EK         P  +    V  L
Sbjct: 1657 FDGNVAHISTWLYQAE---------------ALLDEIEK--------KPTSKQEEIVKRL 1693

Query: 539  ARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSV 597
              +L    +Q+       L  +N R    +  VE +   L E +R+F   SQH  S  +
Sbjct: 1694 VSELDDANLQVENVRDQALILMNARGSSSRELVEPK---LAELNRNFEKVSQHIKSAKL 1749



 Score = 30.4 bits (67), Expect = 9.9
 Identities = 33/150 (22%), Positives = 55/150 (36%), Gaps = 21/150 (14%)

Query: 974  EMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAE 1033
            E +PT        ++ +E K + QH   LE ++Q+ ED N   + QL  L ++++  +  
Sbjct: 762  EGLPTEEIKNVLEKVSSEWKNVSQHLEDLERKIQLQEDINAYFK-QLDELEKVIKTKEEW 820

Query: 1034 AKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSM--------------------GEE 1073
             K    + SS  +     DS Q  L  ++G      M                    G +
Sbjct: 821  VKHTSISESSRQSLPSLKDSCQRELTNLLGLHPKIEMARASCSALMSQPSAPDFVQRGFD 880

Query: 1074 DLLSPPQDTSTGLEEVMEQLNNSFPSSRGH 1103
              L   Q     +E+  + L N      GH
Sbjct: 881  SFLGRYQAVQEAVEDRQQHLENELKGQPGH 910


>gi|148539558 dystrophin related protein 2 [Homo sapiens]
          Length = 957

 Score =  801 bits (2070), Expect = 0.0
 Identities = 412/855 (48%), Positives = 566/855 (66%), Gaps = 49/855 (5%)

Query: 322  MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 381
            MN  W+E++KKS N+R+ LEA SD   +L L LQE++ WL  KD+ELS Q P+ GD   V
Sbjct: 79   MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138

Query: 382  QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 441
            Q++ + H AF  E+K++ P I S LE+ + FL++ P E LE+ + E ++  P++R QN++
Sbjct: 139  QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198

Query: 442  RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 501
            R + KQA   +  WEKL     D  R I+ TLE+L E+Q A +EL   L QAE ++ +W+
Sbjct: 199  RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258

Query: 502  PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 561
            P+GDL IDSL +H++ +K  + E +P+K+ V  VNDLA QL    + LS  N   LE +N
Sbjct: 259  PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318

Query: 562  TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 621
             RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT
Sbjct: 319  VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378

Query: 622  CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 681
            CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A +  ++H+L+ +
Sbjct: 379  CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438

Query: 682  DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 741
            +  MD++++I+CLT +Y+RLE+E   LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT
Sbjct: 439  EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498

Query: 742  GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 801
            GI  LC   +++K +YLF QVA+S   CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP
Sbjct: 499  GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558

Query: 802  SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 861
            SVRSCF+F+  KP IEA+ FL+W+ LEPQSMVWL VLHRV  AE  KHQ KC+IC++CPI
Sbjct: 559  SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618

Query: 862  IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 921
             GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA  LKNKFR
Sbjct: 619  KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678

Query: 922  TKRYFAKHPRMGYLPVQTVLEGDNMET--------------------NLQAEYDRLKQQH 961
            +K YF+KHP+ GYLPVQ+VLE D  ET                    +  AE +      
Sbjct: 679  SKHYFSKHPQRGYLPVQSVLEADYSETPASSPMWPHADTHSRIEHFASRLAEMESQNCSF 738

Query: 962  EHKGLSPLPSPPE----MMPTSPQSPRDAELIAEA--KLLRQHKGRLEARMQILEDHNKQ 1015
             +  LSP  S  E    +  +SP + R+     +A   +  + KG L+  +  LED N+ 
Sbjct: 739  FNDSLSPDDSIDEDQYLLRHSSPITDREPAFGQQAPCSVATESKGELQKILAHLEDENRI 798

Query: 1016 LESQLHRLR-QLLEQPQAEAKVNGTT----------VSSPSTSLQRSDSSQPMLLRVVGS 1064
            L+ +L RL+ Q  E  +A +  +G+T          + + +  L++  S     ++++  
Sbjct: 799  LQGELRRLKWQHEEAAEAPSLADGSTEAATDHRNEELLAEARILRQHKSRLETRMQILED 858

Query: 1065 QTSDSMGE-----EDLLSPPQDT------STGLEEVMEQLNNSFPSSRGHNVGSLFHMAD 1113
                   +     E LL PP ++       + L    +Q   S P  +G         AD
Sbjct: 859  HNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEGSHPREKGQTTPDT-EAAD 917

Query: 1114 DLGRAMESLVSVMTD 1128
            D+G   + +   + D
Sbjct: 918  DVGSKSQDVSLCLED 932



 Score =  129 bits (323), Expect = 2e-29
 Identities = 76/156 (48%), Positives = 100/156 (64%), Gaps = 5/156 (3%)

Query: 950  LQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQIL 1009
            LQ E  RLK QHE    +  PS  +    +    R+ EL+AEA++LRQHK RLE RMQIL
Sbjct: 799  LQGELRRLKWQHEEA--AEAPSLADGSTEAATDHRNEELLAEARILRQHKSRLETRMQIL 856

Query: 1010 EDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDS 1069
            EDHNKQLESQL RLR+LL QP  E+  +G+  SS ++S Q+S+ S P   R  G  T D+
Sbjct: 857  EDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEGSHP---REKGQTTPDT 913

Query: 1070 MGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNV 1105
               +D+ S  QD S  LE++ME+L ++FPS R  +V
Sbjct: 914  EAADDVGSKSQDVSLCLEDIMEKLRHAFPSVRSSDV 949



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 33/235 (14%)

Query: 21  ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNK 80
           E+ DWLS  D+ + +Q  + GD+  + +      A M++++ R P +  ++ +AQ   ++
Sbjct: 113 EIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQ 172

Query: 81  TSNQE-----ARTIITDRIERIQN--------------QWDEVQEHLQNRRQQLNEMLKD 121
              +E     + +  T   +RIQN               W+++     ++ + +   L+ 
Sbjct: 173 HPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQ 232

Query: 122 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
             +   A EE    L QA     +W+  G   +D++ + I   K   ++    +  V + 
Sbjct: 233 LLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLV 292

Query: 181 NDLALKLLRDYSADDTRKVHMITEN------INASWRSIHKRVSEREAALEETHR 229
           NDLA +L           VH+  EN      IN  W+ +   VSER   L++ HR
Sbjct: 293 NDLAHQLA-------ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHR 340


>gi|5032303 dystrophin Dp71ab isoform [Homo sapiens]
          Length = 622

 Score =  701 bits (1808), Expect = 0.0
 Identities = 355/445 (79%), Positives = 373/445 (83%), Gaps = 39/445 (8%)

Query: 616  HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 675
            HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ
Sbjct: 8    HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67

Query: 676  HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 735
            HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR
Sbjct: 68   HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127

Query: 736  VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 795
            VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG
Sbjct: 128  VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187

Query: 796  GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 855
            GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI
Sbjct: 188  GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247

Query: 856  CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 915
            CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV
Sbjct: 248  CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307

Query: 916  LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET---NLQAEYDRLKQQHEHKG------- 965
            LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET   + Q  +D    + EH         
Sbjct: 308  LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPASSPQLSHDDTHSRIEHYASRLAEME 367

Query: 966  ------LSPLPSPPEMMP-------------------TSPQSPRDAELIAEAKLLRQHKG 1000
                  L+   SP E +                    + P+SP    +  E+    + +G
Sbjct: 368  NSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLES----EERG 423

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQ 1025
             LE  +  LE+ N+ L+++  RL+Q
Sbjct: 424  ELERILADLEEENRNLQAEYDRLKQ 448



 Score =  365 bits (936), Expect = e-100
 Identities = 188/193 (97%), Positives = 189/193 (97%), Gaps = 2/193 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 432  LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 489

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 490  RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 549

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAME 1120
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAME
Sbjct: 550  VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAME 609

Query: 1121 SLVSVMTDEEGAE 1133
            SLVSVMTDEEGAE
Sbjct: 610  SLVSVMTDEEGAE 622


>gi|5032301 dystrophin Dp71a isoform [Homo sapiens]
          Length = 604

 Score =  701 bits (1808), Expect = 0.0
 Identities = 355/445 (79%), Positives = 373/445 (83%), Gaps = 39/445 (8%)

Query: 616  HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 675
            HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ
Sbjct: 8    HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67

Query: 676  HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 735
            HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR
Sbjct: 68   HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127

Query: 736  VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 795
            VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG
Sbjct: 128  VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187

Query: 796  GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 855
            GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI
Sbjct: 188  GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247

Query: 856  CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 915
            CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV
Sbjct: 248  CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307

Query: 916  LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET---NLQAEYDRLKQQHEHKG------- 965
            LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET   + Q  +D    + EH         
Sbjct: 308  LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPASSPQLSHDDTHSRIEHYASRLAEME 367

Query: 966  ------LSPLPSPPEMMP-------------------TSPQSPRDAELIAEAKLLRQHKG 1000
                  L+   SP E +                    + P+SP    +  E+    + +G
Sbjct: 368  NSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLES----EERG 423

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQ 1025
             LE  +  LE+ N+ L+++  RL+Q
Sbjct: 424  ELERILADLEEENRNLQAEYDRLKQ 448



 Score =  306 bits (785), Expect = 6e-83
 Identities = 158/164 (96%), Positives = 159/164 (96%), Gaps = 2/164 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 432  LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 489

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 490  RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 549

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1104
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N
Sbjct: 550  VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 593


>gi|5032299 dystrophin Dp71b isoform [Homo sapiens]
          Length = 635

 Score =  696 bits (1796), Expect = 0.0
 Identities = 355/458 (77%), Positives = 373/458 (81%), Gaps = 52/458 (11%)

Query: 616  HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 675
            HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ
Sbjct: 8    HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67

Query: 676  HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 735
            HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR
Sbjct: 68   HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127

Query: 736  VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 795
            VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG
Sbjct: 128  VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187

Query: 796  GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 855
            GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI
Sbjct: 188  GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247

Query: 856  CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 915
            CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV
Sbjct: 248  CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307

Query: 916  LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNL----------------QAEYDRLKQ 959
            LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET +                Q  +D    
Sbjct: 308  LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 367

Query: 960  QHEHKG-------------LSPLPSPPEMMP-------------------TSPQSPRDAE 987
            + EH               L+   SP E +                    + P+SP    
Sbjct: 368  RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 427

Query: 988  LIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQ 1025
            +  E+    + +G LE  +  LE+ N+ L+++  RL+Q
Sbjct: 428  ISLES----EERGELERILADLEEENRNLQAEYDRLKQ 461



 Score =  365 bits (936), Expect = e-100
 Identities = 188/193 (97%), Positives = 189/193 (97%), Gaps = 2/193 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 445  LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 502

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 503  RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 562

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAME 1120
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAME
Sbjct: 563  VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNVGSLFHMADDLGRAME 622

Query: 1121 SLVSVMTDEEGAE 1133
            SLVSVMTDEEGAE
Sbjct: 623  SLVSVMTDEEGAE 635


>gi|5032297 dystrophin Dp71 isoform [Homo sapiens]
          Length = 617

 Score =  696 bits (1796), Expect = 0.0
 Identities = 355/458 (77%), Positives = 373/458 (81%), Gaps = 52/458 (11%)

Query: 616  HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 675
            HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ
Sbjct: 8    HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67

Query: 676  HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 735
            HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR
Sbjct: 68   HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127

Query: 736  VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 795
            VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG
Sbjct: 128  VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187

Query: 796  GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 855
            GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI
Sbjct: 188  GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247

Query: 856  CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 915
            CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV
Sbjct: 248  CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307

Query: 916  LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNL----------------QAEYDRLKQ 959
            LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET +                Q  +D    
Sbjct: 308  LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 367

Query: 960  QHEHKG-------------LSPLPSPPEMMP-------------------TSPQSPRDAE 987
            + EH               L+   SP E +                    + P+SP    
Sbjct: 368  RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 427

Query: 988  LIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQ 1025
            +  E+    + +G LE  +  LE+ N+ L+++  RL+Q
Sbjct: 428  ISLES----EERGELERILADLEEENRNLQAEYDRLKQ 461



 Score =  306 bits (785), Expect = 6e-83
 Identities = 158/164 (96%), Positives = 159/164 (96%), Gaps = 2/164 (1%)

Query: 941  LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000
            LE +N   NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG
Sbjct: 445  LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 502

Query: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060
            RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR
Sbjct: 503  RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 562

Query: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1104
            VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N
Sbjct: 563  VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 606


>gi|5032305 dystrophin Dp40 isoform [Homo sapiens]
          Length = 340

 Score =  693 bits (1789), Expect = 0.0
 Identities = 333/333 (100%), Positives = 333/333 (100%)

Query: 616 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 675
           HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ
Sbjct: 8   HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67

Query: 676 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 735
           HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR
Sbjct: 68  HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127

Query: 736 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 795
           VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG
Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187

Query: 796 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 855
           GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI
Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247

Query: 856 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 915
           CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV
Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307

Query: 916 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET 948
           LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET
Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET 340


>gi|15147341 dystrobrevin, beta isoform 3 [Homo sapiens]
          Length = 567

 Score =  161 bits (407), Expect = 4e-39
 Identities = 136/514 (26%), Positives = 227/514 (44%), Gaps = 84/514 (16%)

Query: 641  VRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDIL--QIINCLTTIY 698
            +R S YRTA KLR +QK   L L+ +    +A   + L   D   +I   ++   +++IY
Sbjct: 30   IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIY 89

Query: 699  DRLEQE--HNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYR 756
             +L +     + ++V   + + LN+++  YD+   G++ V S K  + ++C   + DK R
Sbjct: 90   YQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLR 149

Query: 757  YLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEI 816
            Y+F Q++ S G     +    L + +++P  + E  SFG +  E SVR+CF     + +I
Sbjct: 150  YVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCFP---QQRKI 204

Query: 817  EAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNY 874
               +FLD M  +P  Q +VWLP++HR+A  E   H  +C+ C+   ++GFRYR  +  NY
Sbjct: 205  MLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNY 264

Query: 875  DICQSCFFSGRVAKGHKMHYPMVEY-------------------CTPT---------TSG 906
             +CQ+CF+ G     H   + M E+                   C PT            
Sbjct: 265  QLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPTREPPHPVFPEQP 324

Query: 907  EDVRDFAKVLKNKFRTKR--YFAKHPRMGY-LPVQTVLEGDNM----------------- 946
            E   D A ++  +  T        H   G   P ++VL+  +                  
Sbjct: 325  EKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKSVLDSPSRLDEEHRLIARYAARLAA 384

Query: 947  --------ETNLQAEYDRLKQQH------EHKGLSPLPSPPEM--------MPTSPQSPR 984
                     T+L   +D  KQQ       E+K    L     +         PT  ++ +
Sbjct: 385  EAGNVTRPPTDLSFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQ 444

Query: 985  DAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSP 1044
            +  L+AE +LLRQ K  LE RM  L++  ++L  QL  L +LL++ + +     T   SP
Sbjct: 445  NPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQAT--GSP 502

Query: 1045 STS-LQRSDSSQPMLLRVVGSQTSDSMGEEDLLS 1077
             TS         PM +R   + ++ +   +D LS
Sbjct: 503  HTSPTHGGGRPMPMPVRSTSAGSTPTHCPQDSLS 536



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 35/160 (21%), Positives = 71/160 (44%), Gaps = 22/160 (13%)

Query: 215 KRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLL--EDSKGVK 272
           K V +  + L+E HRL+ ++   L      +T   T  +   DA +++R L  E     +
Sbjct: 359 KSVLDSPSRLDEEHRLIARYAARLAAEAGNVTRPPTDLSFNFDANKQQRQLIAELENKNR 418

Query: 273 ELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332
           E++++ Q L+ E   H        E +Q+        +  +L + RL         LR++
Sbjct: 419 EILQEIQRLRLE---HEQASQPTPEKAQQ--------NPTLLAELRL---------LRQR 458

Query: 333 SLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372
              +   + A  +  + L + L+EL+  L+ ++ + + QA
Sbjct: 459 KDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQA 498


>gi|37577097 dystrobrevin, beta isoform 5 [Homo sapiens]
          Length = 560

 Score =  158 bits (400), Expect = 2e-38
 Identities = 136/513 (26%), Positives = 228/513 (44%), Gaps = 89/513 (17%)

Query: 641  VRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDIL--QIINCLTTIY 698
            +R S YRTA KLR +QK   L L+ +    +A   + L   D   +I   ++   +++IY
Sbjct: 30   IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIY 89

Query: 699  DRLEQE--HNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYR 756
             +L +     + ++V   + + LN+++  YD+   G++ V S K  + ++C   + DK R
Sbjct: 90   YQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLR 149

Query: 757  YLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEI 816
            Y+F Q++ S G     +    L + +++P  + E  SFG +  E SVR+CF     + +I
Sbjct: 150  YVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCFP---QQRKI 204

Query: 817  EAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNY 874
               +FLD M  +P  Q +VWLP++HR+A  E   H  +C+ C+   ++GFRYR  +  NY
Sbjct: 205  MLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNY 264

Query: 875  DICQSCFFSGRVAKGHKMHYPMVEY-------------------CTPT---------TSG 906
             +CQ+CF+ G     H   + M E+                   C PT            
Sbjct: 265  QLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPTREPPHPVFPEQP 324

Query: 907  EDVRDFAKVLKNKFRTKR--YFAKHPRMGY-LPVQTVLEGDNM----------------- 946
            E   D A ++  +  T        H   G   P ++VL+  +                  
Sbjct: 325  EKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKSVLDSPSRLDEEHRLIARYAARLAA 384

Query: 947  --------ETNLQAEYDRLKQQH------EHKGLSPLPSPPEM--------MPTSPQSPR 984
                     T+L   +D  KQQ       E+K    L     +         PT  ++ +
Sbjct: 385  EAGNVTRPPTDLSFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQ 444

Query: 985  DAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSP 1044
            +  L+AE +LLRQ K  LE RM  L++  ++L  QL  L +LL     +A+  G+  +SP
Sbjct: 445  NPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLL-----KAQATGSPHTSP 499

Query: 1045 STSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLS 1077
            +    R     PM +R   + ++ +   +D LS
Sbjct: 500  THGGGR---PMPMPVRSTSAGSTPTHCPQDSLS 529



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 30/129 (23%), Positives = 58/129 (44%), Gaps = 8/129 (6%)

Query: 215 KRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLL--EDSKGVK 272
           K V +  + L+E HRL+ ++   L      +T   T  +   DA +++R L  E     +
Sbjct: 359 KSVLDSPSRLDEEHRLIARYAARLAAEAGNVTRPPTDLSFNFDANKQQRQLIAELENKNR 418

Query: 273 ELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332
           E++++ Q L+ E E  +       + +  +L  L       LL++R D +  + S L++ 
Sbjct: 419 EILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELR------LLRQRKDELEQRMSALQES 472

Query: 333 SLNIRSHLE 341
              +   LE
Sbjct: 473 RRELMVQLE 481


>gi|157364926 dystrotelin [Homo sapiens]
          Length = 578

 Score =  156 bits (395), Expect = 9e-38
 Identities = 114/395 (28%), Positives = 188/395 (47%), Gaps = 49/395 (12%)

Query: 638  LNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNL-KQNDQPMDILQIINCLTT 696
            LN++  S YRTA KL+ +Q    LDL+  S     L + +  +     + + Q+   L  
Sbjct: 9    LNSIENSIYRTAFKLQSVQTLCQLDLIDSSLIQQVLLRPSFWEARKHSLSVQQLSQALQE 68

Query: 697  IYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYR 756
            ++ +  +E+   V+ P   ++ L+ L  +Y++  TG ++++     +I+L       KYR
Sbjct: 69   LFQKAREENPGQVH-PRAPELTLSLLTTMYNSKGTGFLQLMPAAAALITLSGDSPLSKYR 127

Query: 757  YLFKQVA-SSTGFCD------QRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQF 809
             LF+  A +S G  D      +R L  LL D  QIP  +GE  +     +E + RSCFQ 
Sbjct: 128  ALFQLYAENSRGGYDSGPRMTRRVLRKLLTDLQQIPTFVGESRAL--CPVESATRSCFQG 185

Query: 810  ANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSL 869
              + P I+   FL W++ EP  ++WLP  HR++AAE   H A+C +C+  PI G RYR L
Sbjct: 186  VLS-PAIKEEKFLSWVQSEPPILLWLPTCHRLSAAERVTHPARCTLCRTFPITGLRYRCL 244

Query: 870  KHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKH 929
            K  N+DICQ CF SG  +K H+  +P++E+C   ++ ++ +   + L+N     R   K 
Sbjct: 245  KCLNFDICQMCFLSGLHSKSHQKSHPVIEHCIQMSAMQNTKLLFRTLRNNLLQGRCRKKE 304

Query: 930  PRMGYLPVQTVLEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELI 989
                                  A   +L  Q   KG+                P  A+  
Sbjct: 305  ---------------------AARRQQLLDQVNPKGV----------------PHHAQAR 327

Query: 990  AEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLR 1024
               K L Q+K +L+A     E+   + E+++H+L+
Sbjct: 328  LLKKQLNQYKDKLQAIYTSQEERICRFETRIHKLK 362


>gi|42717999 dystrobrevin alpha isoform 2 [Homo sapiens]
          Length = 686

 Score =  149 bits (375), Expect = 2e-35
 Identities = 143/573 (24%), Positives = 240/573 (41%), Gaps = 89/573 (15%)

Query: 637  DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 694
            DL+ +R S YRTA KLR +QK   L L+ +    +AL ++ L   D    +++ ++   L
Sbjct: 26   DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85

Query: 695  TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 752
            +TI+ +L +     + ++V   + + LN+LL  +D    G+I V + K  + +LC   + 
Sbjct: 86   STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145

Query: 753  DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 812
            DK RY+F  ++ S+G     R    L + +++P  + E  SFG +  E S RSCF   + 
Sbjct: 146  DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200

Query: 813  KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 870
            + ++    FLD +  +P  Q +VWLP+LHR+A  E   H  +C+ C    ++GFRYR  +
Sbjct: 201  QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260

Query: 871  HFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRD-FAKVLKNKFRTKRYFAKH 929
              NY +CQ CF+ G     H   + M EY +  +  + + +  +K L      +      
Sbjct: 261  CHNYQLCQDCFWRGHAGGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSREPLHPMF 320

Query: 930  PRMGYLPVQTVLEGDN-------------------------METNLQAEYDRLKQQHEHK 964
            P     P+      D                          +  ++    +RL ++H   
Sbjct: 321  PDQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSVPSSGSPFITRSMLESSNRLDEEHRLI 380

Query: 965  GLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLR 1024
                     E   + P   R A  I+      + + +L A    LE+ N+++  ++ RLR
Sbjct: 381  ARYAARLAAESSSSQPPQQRSAPDISFTIDANKQQRQLIAE---LENKNREILQEIQRLR 437

Query: 1025 QLLEQPQA------EAKVNGTTVSSPSTSLQRSDSSQP--------------------ML 1058
              LE  QA      +A+ N T ++      QR D  +                      L
Sbjct: 438  --LEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKL 495

Query: 1059 LRVVGSQTSDSMGEEDLLSP-----------------PQDTSTGLEEVMEQLNNSFPSSR 1101
            L+  G+ +  S     +  P                 PQD+ TG   V   +  +F  S 
Sbjct: 496  LKTQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTG---VGGDVQEAFAQSS 552

Query: 1102 GHNV-GSLFHMADDLGRAMESLVSVMTDEEGAE 1133
              N+   L   AD +   M SLV  +  E G+E
Sbjct: 553  RRNLRNDLLVAADSITNTMSSLVKELNSEVGSE 585


>gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens]
          Length = 743

 Score =  148 bits (374), Expect = 3e-35
 Identities = 88/269 (32%), Positives = 144/269 (53%), Gaps = 11/269 (4%)

Query: 637 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 694
           DL+ +R S YRTA KLR +QK   L L+ +    +AL ++ L   D    +++ ++   L
Sbjct: 26  DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85

Query: 695 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 752
           +TI+ +L +     + ++V   + + LN+LL  +D    G+I V + K  + +LC   + 
Sbjct: 86  STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145

Query: 753 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 812
           DK RY+F  ++ S+G     R    L + +++P  + E  SFG +  E S RSCF   + 
Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200

Query: 813 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 870
           + ++    FLD +  +P  Q +VWLP+LHR+A  E   H  +C+ C    ++GFRYR  +
Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260

Query: 871 HFNYDICQSCFFSGRVAKGHKMHYPMVEY 899
             NY +CQ CF+ G     H   + M EY
Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEY 289



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 60/197 (30%), Positives = 89/197 (45%), Gaps = 29/197 (14%)

Query: 938  QTVLEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQ 997
            Q + E +N    +  E  RL+ +HE     P P   +  PT         L+AE +LLRQ
Sbjct: 474  QLIAELENKNREILQEIQRLRLEHEQAS-QPTPEKAQQNPT---------LLAELRLLRQ 523

Query: 998  HKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPM 1057
             K  LE RM  L++  ++L  QL  L +LL+   A     G+  SSPS ++ R     PM
Sbjct: 524  RKDELEQRMSALQESRRELMVQLEGLMKLLKTQGA-----GSPRSSPSHTISR---PIPM 575

Query: 1058 LLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNV-GSLFHMADDLG 1116
             +R   + ++ +         PQD+ TG   V   +  +F  S   N+   L   AD + 
Sbjct: 576  PIRSASACSTPT-------HTPQDSLTG---VGGDVQEAFAQSSRRNLRNDLLVAADSIT 625

Query: 1117 RAMESLVSVMTDEEGAE 1133
              M SLV  +  E G+E
Sbjct: 626  NTMSSLVKELNSEVGSE 642


>gi|42718003 dystrobrevin alpha isoform 3 [Homo sapiens]
          Length = 570

 Score =  148 bits (374), Expect = 3e-35
 Identities = 88/269 (32%), Positives = 144/269 (53%), Gaps = 11/269 (4%)

Query: 637 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 694
           DL+ +R S YRTA KLR +QK   L L+ +    +AL ++ L   D    +++ ++   L
Sbjct: 26  DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85

Query: 695 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 752
           +TI+ +L +     + ++V   + + LN+LL  +D    G+I V + K  + +LC   + 
Sbjct: 86  STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145

Query: 753 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 812
           DK RY+F  ++ S+G     R    L + +++P  + E  SFG +  E S RSCF   + 
Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200

Query: 813 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 870
           + ++    FLD +  +P  Q +VWLP+LHR+A  E   H  +C+ C    ++GFRYR  +
Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260

Query: 871 HFNYDICQSCFFSGRVAKGHKMHYPMVEY 899
             NY +CQ CF+ G     H   + M EY
Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEY 289



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 32/100 (32%), Positives = 50/100 (50%), Gaps = 10/100 (10%)

Query: 938  QTVLEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQ 997
            Q + E +N    +  E  RL+ +HE     P P   +  PT         L+AE +LLRQ
Sbjct: 474  QLIAELENKNREILQEIQRLRLEHEQAS-QPTPEKAQQNPT---------LLAELRLLRQ 523

Query: 998  HKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVN 1037
             K  LE RM  L++  ++L  QL  L +LL++ + +  V+
Sbjct: 524  RKDELEQRMSALQESRRELMVQLEGLMKLLKEEELKQGVS 563


>gi|42718001 dystrobrevin alpha isoform 4 [Homo sapiens]
          Length = 567

 Score =  148 bits (374), Expect = 3e-35
 Identities = 88/269 (32%), Positives = 144/269 (53%), Gaps = 11/269 (4%)

Query: 637 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 694
           DL+ +R S YRTA KLR +QK   L L+ +    +AL ++ L   D    +++ ++   L
Sbjct: 26  DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85

Query: 695 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 752
           +TI+ +L +     + ++V   + + LN+LL  +D    G+I V + K  + +LC   + 
Sbjct: 86  STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145

Query: 753 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 812
           DK RY+F  ++ S+G     R    L + +++P  + E  SFG +  E S RSCF   + 
Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200

Query: 813 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 870
           + ++    FLD +  +P  Q +VWLP+LHR+A  E   H  +C+ C    ++GFRYR  +
Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260

Query: 871 HFNYDICQSCFFSGRVAKGHKMHYPMVEY 899
             NY +CQ CF+ G     H   + M EY
Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEY 289



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 32/100 (32%), Positives = 50/100 (50%), Gaps = 10/100 (10%)

Query: 938  QTVLEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQ 997
            Q + E +N    +  E  RL+ +HE     P P   +  PT         L+AE +LLRQ
Sbjct: 471  QLIAELENKNREILQEIQRLRLEHEQAS-QPTPEKAQQNPT---------LLAELRLLRQ 520

Query: 998  HKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVN 1037
             K  LE RM  L++  ++L  QL  L +LL++ + +  V+
Sbjct: 521  RKDELEQRMSALQESRRELMVQLEGLMKLLKEEELKQGVS 560


>gi|42717997 dystrobrevin alpha isoform 5 [Homo sapiens]
          Length = 513

 Score =  148 bits (374), Expect = 3e-35
 Identities = 88/269 (32%), Positives = 144/269 (53%), Gaps = 11/269 (4%)

Query: 637 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 694
           DL+ +R S YRTA KLR +QK   L L+ +    +AL ++ L   D    +++ ++   L
Sbjct: 26  DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85

Query: 695 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 752
           +TI+ +L +     + ++V   + + LN+LL  +D    G+I V + K  + +LC   + 
Sbjct: 86  STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145

Query: 753 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 812
           DK RY+F  ++ S+G     R    L + +++P  + E  SFG +  E S RSCF   + 
Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200

Query: 813 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 870
           + ++    FLD +  +P  Q +VWLP+LHR+A  E   H  +C+ C    ++GFRYR  +
Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260

Query: 871 HFNYDICQSCFFSGRVAKGHKMHYPMVEY 899
             NY +CQ CF+ G     H   + M EY
Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEY 289



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 32/100 (32%), Positives = 50/100 (50%), Gaps = 10/100 (10%)

Query: 938  QTVLEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQ 997
            Q + E +N    +  E  RL+ +HE     P P   +  PT         L+AE +LLRQ
Sbjct: 417  QLIAELENKNREILQEIQRLRLEHEQAS-QPTPEKAQQNPT---------LLAELRLLRQ 466

Query: 998  HKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVN 1037
             K  LE RM  L++  ++L  QL  L +LL++ + +  V+
Sbjct: 467  RKDELEQRMSALQESRRELMVQLEGLMKLLKEEELKQGVS 506


>gi|42717994 dystrobrevin alpha isoform 7 [Homo sapiens]
          Length = 374

 Score =  148 bits (374), Expect = 3e-35
 Identities = 88/269 (32%), Positives = 144/269 (53%), Gaps = 11/269 (4%)

Query: 637 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 694
           DL+ +R S YRTA KLR +QK   L L+ +    +AL ++ L   D    +++ ++   L
Sbjct: 26  DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85

Query: 695 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 752
           +TI+ +L +     + ++V   + + LN+LL  +D    G+I V + K  + +LC   + 
Sbjct: 86  STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145

Query: 753 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 812
           DK RY+F  ++ S+G     R    L + +++P  + E  SFG +  E S RSCF   + 
Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200

Query: 813 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 870
           + ++    FLD +  +P  Q +VWLP+LHR+A  E   H  +C+ C    ++GFRYR  +
Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260

Query: 871 HFNYDICQSCFFSGRVAKGHKMHYPMVEY 899
             NY +CQ CF+ G     H   + M EY
Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEY 289


>gi|189571587 dystrobrevin alpha isoform 9 [Homo sapiens]
          Length = 371

 Score =  148 bits (374), Expect = 3e-35
 Identities = 88/269 (32%), Positives = 144/269 (53%), Gaps = 11/269 (4%)

Query: 637 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 694
           DL+ +R S YRTA KLR +QK   L L+ +    +AL ++ L   D    +++ ++   L
Sbjct: 26  DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85

Query: 695 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 752
           +TI+ +L +     + ++V   + + LN+LL  +D    G+I V + K  + +LC   + 
Sbjct: 86  STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145

Query: 753 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 812
           DK RY+F  ++ S+G     R    L + +++P  + E  SFG +  E S RSCF   + 
Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200

Query: 813 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 870
           + ++    FLD +  +P  Q +VWLP+LHR+A  E   H  +C+ C    ++GFRYR  +
Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260

Query: 871 HFNYDICQSCFFSGRVAKGHKMHYPMVEY 899
             NY +CQ CF+ G     H   + M EY
Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEY 289


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,057,977
Number of Sequences: 37866
Number of extensions: 1892957
Number of successful extensions: 13768
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 138
Number of HSP's successfully gapped in prelim test: 612
Number of HSP's that attempted gapping in prelim test: 9281
Number of HSP's gapped (non-prelim): 3169
length of query: 1133
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1020
effective length of database: 13,968,660
effective search space: 14248033200
effective search space used: 14248033200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.