BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] (261 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 559 e-160 gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens] 449 e-126 gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 435 e-122 gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 363 e-100 gi|71834855 prostate specific antigen isoform 4 preproprotein [H... 355 2e-98 gi|71834857 prostate specific antigen isoform 5 preproprotein [H... 339 1e-93 gi|71834853 prostate specific antigen isoform 3 preproprotein [H... 332 2e-91 gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 231 5e-61 gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 231 5e-61 gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 231 5e-61 gi|11496281 kallikrein 13 precursor [Homo sapiens] 230 1e-60 gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 212 3e-55 gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 212 3e-55 gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 209 3e-54 gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 209 3e-54 gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 208 4e-54 gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 205 4e-53 gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 205 4e-53 gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 204 8e-53 gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 203 1e-52 gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 202 2e-52 gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 202 2e-52 gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 202 2e-52 gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 202 3e-52 gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 199 3e-51 gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 197 6e-51 gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 197 6e-51 gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 192 2e-49 gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 177 6e-45 gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 171 8e-43 >gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] Length = 261 Score = 559 bits (1441), Expect = e-160 Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV Sbjct: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60 Query: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD Sbjct: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120 Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180 Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 240 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP Sbjct: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 240 Query: 241 AVYTKVVHYRKWIKDTIAANP 261 AVYTKVVHYRKWIKDTIAANP Sbjct: 241 AVYTKVVHYRKWIKDTIAANP 261 >gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens] Length = 223 Score = 449 bits (1154), Expect = e-126 Identities = 210/210 (100%), Positives = 210/210 (100%) Query: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV Sbjct: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60 Query: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD Sbjct: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120 Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180 Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCG 210 NDMCARAYSEKVTEFMLCAGLWTGGKDTCG Sbjct: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCG 210 >gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo sapiens] Length = 261 Score = 435 bits (1118), Expect = e-122 Identities = 201/261 (77%), Positives = 225/261 (86%) Query: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60 MW V+ + LSV GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 Query: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120 LTAAHC++ S + LGRH+LF PEDTGQ VSHSFPHPLY+MSLLK++ LRP +DSSHD Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120 Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180 LMLLRLSEPA++TD VKV+ LPTQEPALGTTCYASGWGSIEPEEFL P+ LQCV LH++S Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180 Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 240 ND+CA+ + +KVT+FMLCAG WTGGK TC GDSGGPLVCNGVLQGITSWG EPCALPE+P Sbjct: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 240 Query: 241 AVYTKVVHYRKWIKDTIAANP 261 ++YTKVVHYRKWIKDTI ANP Sbjct: 241 SLYTKVVHYRKWIKDTIVANP 261 >gi|4504875 kallikrein 1 preproprotein [Homo sapiens] Length = 262 Score = 363 bits (931), Expect = e-100 Identities = 172/261 (65%), Positives = 203/261 (77%), Gaps = 1/261 (0%) Query: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60 MW LVL +ALS+G TGA P IQSRIVGGWECE+HSQPWQ A+Y CGG+LVH QWV Sbjct: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60 Query: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120 LTAAHC+ N Q+WLGRHNLF+ E+T Q V VS SFPHP +NMSLL++ + + DED SHD Sbjct: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120 Query: 121 LMLLRLSEPA-KITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLL 179 LMLLRL+EPA ITD VKV+ LPT+EP +G+TC ASGWGSIEPE F P LQCV L +L Sbjct: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180 Query: 180 SNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEK 239 ND C +A+ +KVT+FMLC G GGKDTC GDSGGPL+C+GVLQG+TSWG PC P K Sbjct: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240 Query: 240 PAVYTKVVHYRKWIKDTIAAN 260 P+V +V+ Y KWI+DTIA N Sbjct: 241 PSVAVRVLSYVKWIEDTIAEN 261 >gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo sapiens] Length = 218 Score = 355 bits (912), Expect = 2e-98 Identities = 172/261 (65%), Positives = 191/261 (73%), Gaps = 43/261 (16%) Query: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60 MW V+ + LSV GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 Query: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120 LTAAHC++K P +DSSHD Sbjct: 61 LTAAHCIRK-------------------------------------------PGDDSSHD 77 Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180 LMLLRLSEPA++TD VKV+ LPTQEPALGTTCYASGWGSIEPEEFL P+ LQCV LH++S Sbjct: 78 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 137 Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 240 ND+CA+ + +KVT+FMLCAG WTGGK TC GDSGGPLVCNGVLQGITSWG EPCALPE+P Sbjct: 138 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 197 Query: 241 AVYTKVVHYRKWIKDTIAANP 261 ++YTKVVHYRKWIKDTI ANP Sbjct: 198 SLYTKVVHYRKWIKDTIVANP 218 >gi|71834857 prostate specific antigen isoform 5 preproprotein [Homo sapiens] Length = 220 Score = 339 bits (870), Expect = 1e-93 Identities = 165/261 (63%), Positives = 186/261 (71%), Gaps = 41/261 (15%) Query: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60 MW V+ + LSV GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 Query: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120 LTAAHC++ S + LGRH+LF PEDTGQ VSHSFPHPLY+MSLLK++ LRP +DSS Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSS-- 118 Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180 IEPEEFL P+ LQCV LH++S Sbjct: 119 ---------------------------------------IEPEEFLTPKKLQCVDLHVIS 139 Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 240 ND+CA+ + +KVT+FMLCAG WTGGK TC GDSGGPLVCNGVLQGITSWG EPCALPE+P Sbjct: 140 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 199 Query: 241 AVYTKVVHYRKWIKDTIAANP 261 ++YTKVVHYRKWIKDTI ANP Sbjct: 200 SLYTKVVHYRKWIKDTIVANP 220 >gi|71834853 prostate specific antigen isoform 3 preproprotein [Homo sapiens] Length = 238 Score = 332 bits (852), Expect = 2e-91 Identities = 155/209 (74%), Positives = 176/209 (84%) Query: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60 MW V+ + LSV GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60 Query: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120 LTAAHC++ S + LGRH+LF PEDTGQ VSHSFPHPLY+MSLLK++ LRP +DSSHD Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120 Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180 LMLLRLSEPA++TD VKV+ LPTQEPALGTTCYASGWGSIEPEEFL P+ LQCV LH++S Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180 Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTC 209 ND+CA+ + +KVT+FMLCAG WTGGK TC Sbjct: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTC 209 >gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] Length = 250 Score = 231 bits (589), Expect = 5e-61 Identities = 111/256 (43%), Positives = 159/256 (62%), Gaps = 11/256 (4%) Query: 5 VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAA 64 ++ +AL+ G G ++RI+ G+EC+ HSQPWQ A++ CG L+ P+W+LTAA Sbjct: 6 LILLALATGLVGG----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61 Query: 65 HCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124 HCLK V LG+HNL + E Q + SFPHP +N SL P++D +D+ML+ Sbjct: 62 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 114 Query: 125 RLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184 +++ P IT V+ L L ++ GT+C SGWGS + P +L+C ++ ++ + C Sbjct: 115 KMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 174 Query: 185 ARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYT 244 AY +T+ M+CA + GGKD+C GDSGGPLVCN LQGI SWG +PCA+ KP VYT Sbjct: 175 ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYT 234 Query: 245 KVVHYRKWIKDTIAAN 260 KV Y WI++T+ N Sbjct: 235 KVCKYVDWIQETMKNN 250 >gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] Length = 282 Score = 231 bits (589), Expect = 5e-61 Identities = 111/256 (43%), Positives = 159/256 (62%), Gaps = 11/256 (4%) Query: 5 VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAA 64 ++ +AL+ G G ++RI+ G+EC+ HSQPWQ A++ CG L+ P+W+LTAA Sbjct: 38 LILLALATGLVGG----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93 Query: 65 HCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124 HCLK V LG+HNL + E Q + SFPHP +N SL P++D +D+ML+ Sbjct: 94 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 146 Query: 125 RLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184 +++ P IT V+ L L ++ GT+C SGWGS + P +L+C ++ ++ + C Sbjct: 147 KMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 206 Query: 185 ARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYT 244 AY +T+ M+CA + GGKD+C GDSGGPLVCN LQGI SWG +PCA+ KP VYT Sbjct: 207 ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYT 266 Query: 245 KVVHYRKWIKDTIAAN 260 KV Y WI++T+ N Sbjct: 267 KVCKYVDWIQETMKNN 282 >gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] Length = 250 Score = 231 bits (589), Expect = 5e-61 Identities = 111/256 (43%), Positives = 159/256 (62%), Gaps = 11/256 (4%) Query: 5 VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAA 64 ++ +AL+ G G ++RI+ G+EC+ HSQPWQ A++ CG L+ P+W+LTAA Sbjct: 6 LILLALATGLVGG----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61 Query: 65 HCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124 HCLK V LG+HNL + E Q + SFPHP +N SL P++D +D+ML+ Sbjct: 62 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 114 Query: 125 RLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184 +++ P IT V+ L L ++ GT+C SGWGS + P +L+C ++ ++ + C Sbjct: 115 KMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 174 Query: 185 ARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYT 244 AY +T+ M+CA + GGKD+C GDSGGPLVCN LQGI SWG +PCA+ KP VYT Sbjct: 175 ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYT 234 Query: 245 KVVHYRKWIKDTIAAN 260 KV Y WI++T+ N Sbjct: 235 KVCKYVDWIQETMKNN 250 >gi|11496281 kallikrein 13 precursor [Homo sapiens] Length = 277 Score = 230 bits (586), Expect = 1e-60 Identities = 123/271 (45%), Positives = 158/271 (58%), Gaps = 23/271 (8%) Query: 1 MWDLVLSIA-LSVGCTGAVPLIQSRIV----------GGWECEKHSQPWQVAVYSHGWAH 49 MW L L IA L++ +G V S+++ GG+ C HSQPWQ A+ G Sbjct: 1 MWPLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLL 60 Query: 50 CGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSL--LK 107 CGGVLVHP+WVLTAAHCLK+ +V+LG+H L E Q V HS PHP Y S L Sbjct: 61 CGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLN 120 Query: 108 HQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPAL-GTTCYASGWGSIEPEEFL 166 H HD+MLL L P ++T ++ L L GTTC SGWG+ + Sbjct: 121 HD---------HDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVN 171 Query: 167 RPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGI 226 P++LQC ++ L S++ C + Y K+T+ MLCAG GGKD+C GDSGGPLVCN L GI Sbjct: 172 YPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGI 231 Query: 227 TSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 SWG PC P++P VYT+V Y WI++TI Sbjct: 232 VSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262 >gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein [Homo sapiens] Length = 244 Score = 212 bits (539), Expect = 3e-55 Identities = 106/238 (44%), Positives = 146/238 (61%), Gaps = 13/238 (5%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 Q+++V G C+K S P+Q A+Y+ G CGGVL+HP WVLTAAHC K N QV+LG+HNL Sbjct: 19 QNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLR 78 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 + E + ++ V + HP Y+ + D+MLLRL+ PAK++++++ L L Sbjct: 79 QRESSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAKLSELIQPLPL 127 Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201 A T+C+ GWG +F P ++QC +HL+S + C AY ++T+ MLCAG Sbjct: 128 ERDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGD 185 Query: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259 GKD+C GDSGGPLVC L+G+ SWG PC EKP VYT V Y WI+ TI A Sbjct: 186 EKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243 >gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein [Homo sapiens] Length = 244 Score = 212 bits (539), Expect = 3e-55 Identities = 106/238 (44%), Positives = 146/238 (61%), Gaps = 13/238 (5%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 Q+++V G C+K S P+Q A+Y+ G CGGVL+HP WVLTAAHC K N QV+LG+HNL Sbjct: 19 QNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLR 78 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 + E + ++ V + HP Y+ + D+MLLRL+ PAK++++++ L L Sbjct: 79 QRESSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAKLSELIQPLPL 127 Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201 A T+C+ GWG +F P ++QC +HL+S + C AY ++T+ MLCAG Sbjct: 128 ERDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGD 185 Query: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259 GKD+C GDSGGPLVC L+G+ SWG PC EKP VYT V Y WI+ TI A Sbjct: 186 EKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243 >gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] Length = 305 Score = 209 bits (531), Expect = 3e-54 Identities = 105/238 (44%), Positives = 136/238 (57%), Gaps = 9/238 (3%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 + +++GG EC+ HSQPWQ A++ CGGVLV WVLTAAHC K V LG H+L Sbjct: 75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 + Q +PV S PHP YN S + ED +HDLMLL+L + A + VK + L Sbjct: 135 NKDGPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISL 186 Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201 G C SGWG++ P +L C + + C AY ++T+ M+CAG Sbjct: 187 ADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS 246 Query: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259 + G DTC GDSGGPLVC+G LQGITSWG +PC +KP VYT + Y WIK I + Sbjct: 247 -SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303 >gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] Length = 260 Score = 209 bits (531), Expect = 3e-54 Identities = 105/238 (44%), Positives = 136/238 (57%), Gaps = 9/238 (3%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 + +++GG EC+ HSQPWQ A++ CGGVLV WVLTAAHC K V LG H+L Sbjct: 30 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 89 Query: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 + Q +PV S PHP YN S + ED +HDLMLL+L + A + VK + L Sbjct: 90 NKDGPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISL 141 Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201 G C SGWG++ P +L C + + C AY ++T+ M+CAG Sbjct: 142 ADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS 201 Query: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259 + G DTC GDSGGPLVC+G LQGITSWG +PC +KP VYT + Y WIK I + Sbjct: 202 -SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 258 >gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] Length = 247 Score = 208 bits (529), Expect = 4e-54 Identities = 108/237 (45%), Positives = 141/237 (59%), Gaps = 13/237 (5%) Query: 24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83 +IVGG+ CE++S P+QV++ S G+ CGG L++ QWV++A HC K QV LG HN+ Sbjct: 23 KIVGGYNCEENSVPYQVSLNS-GYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVL 81 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 E Q + + HP Y+ L ++D+ML++LS A I V + LPT Sbjct: 82 EGNEQFINAAKIIRHPQYDRKTL-----------NNDIMLIKLSSRAVINARVSTISLPT 130 Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203 PA GT C SGWG+ P LQC+ +LS C +Y K+T M C G Sbjct: 131 APPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLE 190 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKD+C GDSGGP+VCNG LQG+ SWG + CA KP VYTKV +Y KWIK+TIAAN Sbjct: 191 GGKDSCQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAAN 246 >gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] Length = 250 Score = 205 bits (521), Expect = 4e-53 Identities = 99/233 (42%), Positives = 139/233 (59%), Gaps = 7/233 (3%) Query: 23 SRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82 +R +G EC +SQPWQ ++ CG L+ +W+LTAAHC K V LG H+L++ Sbjct: 21 TRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEHHLWK 80 Query: 83 PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142 E Q V+ FPHP +N L + D + D+ML+RL A+++ V+ L L Sbjct: 81 WEGPEQLFRVTDFFPHPGFNKDLSAN-------DHNDDIMLIRLPRQARLSPAVQPLNLS 133 Query: 143 TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLW 202 + G C SGWG++ + L P +LQC ++ +L N +C AY +++ MLCAGLW Sbjct: 134 QTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLW 193 Query: 203 TGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKD 255 GG+ +C GDSGGPLVCNG L G+ S G EPC+ P +PAVYT V HY WI++ Sbjct: 194 EGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQE 246 >gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein [Homo sapiens] Length = 256 Score = 205 bits (521), Expect = 4e-53 Identities = 113/272 (41%), Positives = 153/272 (56%), Gaps = 28/272 (10%) Query: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60 MW L+L+++ + T A +++ G EC HSQPWQVA+Y G +CG L+ P WV Sbjct: 1 MW-LLLTLSFLLASTAAQD--GDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWV 57 Query: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSH- 119 L+AAHC + +V LG HNL + + Q S PHP Y E SH Sbjct: 58 LSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRY-------------EARSHR 104 Query: 120 -DLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSI---EPEEFLRPRS----- 170 D+MLLRL +PA++ V+ LPT+ P G C SGWG + EP PRS Sbjct: 105 NDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLP 164 Query: 171 --LQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITS 228 L C ++ ++S+ C ++Y ++T M+CAG G ++C GDSGGPLVC G+LQGI S Sbjct: 165 DTLHCANISIISDTSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVS 224 Query: 229 WGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 WG PC KP VYTKV HY +WI++T+ N Sbjct: 225 WGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256 >gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] Length = 247 Score = 204 bits (518), Expect = 8e-53 Identities = 112/250 (44%), Positives = 142/250 (56%), Gaps = 14/250 (5%) Query: 12 VGCTGAVPLIQS-RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKN 70 VG AVP +IVGG+ CE++S P+QV++ S G CGG L+ QWV++AAHC K Sbjct: 10 VGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTR 68 Query: 71 SQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPA 130 QV LG HN+ E Q + + HP YN L +D+ML++LS PA Sbjct: 69 IQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTL-----------DNDIMLIKLSSPA 117 Query: 131 KITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190 I V + LPT PA GT C SGWG+ P L+C+ +L+ C +Y Sbjct: 118 VINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPG 177 Query: 191 KVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYR 250 K+T M C G GGKD+C DSGGP+VCNG LQG+ SWG CA +P VYTKV +Y Sbjct: 178 KITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYV 236 Query: 251 KWIKDTIAAN 260 WIKDTIAAN Sbjct: 237 DWIKDTIAAN 246 >gi|91823048 kallikrein 14 preproprotein [Homo sapiens] Length = 267 Score = 203 bits (516), Expect = 1e-52 Identities = 104/238 (43%), Positives = 143/238 (60%), Gaps = 13/238 (5%) Query: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCLKKNSQVWLGRHN 79 +++I+GG C + SQPWQ A+ + CGG L+ QWV+TAAHC + QV LG+HN Sbjct: 38 ENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHN 97 Query: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139 L E T Q + V HP YN +DLMLL+L +PA+I V+ + Sbjct: 98 LRRWEATQQVLRVVRQVTHPNYN-----------SRTHDNDLMLLQLQQPARIGRAVRPI 146 Query: 140 GLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCA 199 + + GT+C SGWG+I P SLQCV++++ +++C +AY +T M+CA Sbjct: 147 EVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCA 206 Query: 200 GLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257 G+ GGKD+C GDSGGPLVC G LQG+ SWG E CALP P VYT + YR WI++T+ Sbjct: 207 GVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETM 264 >gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo sapiens] Length = 293 Score = 202 bits (514), Expect = 2e-52 Identities = 102/240 (42%), Positives = 147/240 (61%), Gaps = 14/240 (5%) Query: 23 SRIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 SRI+ G +C+ H+QPWQ A+ +CG VLVHPQW+LTAAHC KK +V LG ++L Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124 Query: 82 EPEDTGQRVPVS-HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 ++GQ++ S PHP Y+ S+DLML++L+ + T V+ + Sbjct: 125 PVYESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIKLNRRIRPTKDVRPIN 173 Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAG 200 + + P+ GT C SGWG+ + + P+ LQC+++ +LS C AY ++ + M CAG Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233 Query: 201 LWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 G+D+C GDSGGP+VCNG LQG+ SWG PCA P +P VYT + + KWI++TI AN Sbjct: 234 D-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292 >gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo sapiens] Length = 293 Score = 202 bits (514), Expect = 2e-52 Identities = 102/240 (42%), Positives = 147/240 (61%), Gaps = 14/240 (5%) Query: 23 SRIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 SRI+ G +C+ H+QPWQ A+ +CG VLVHPQW+LTAAHC KK +V LG ++L Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124 Query: 82 EPEDTGQRVPVS-HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 ++GQ++ S PHP Y+ S+DLML++L+ + T V+ + Sbjct: 125 PVYESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIKLNRRIRPTKDVRPIN 173 Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAG 200 + + P+ GT C SGWG+ + + P+ LQC+++ +LS C AY ++ + M CAG Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233 Query: 201 LWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 G+D+C GDSGGP+VCNG LQG+ SWG PCA P +P VYT + + KWI++TI AN Sbjct: 234 D-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292 >gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sapiens] Length = 293 Score = 202 bits (514), Expect = 2e-52 Identities = 102/240 (42%), Positives = 147/240 (61%), Gaps = 14/240 (5%) Query: 23 SRIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 SRI+ G +C+ H+QPWQ A+ +CG VLVHPQW+LTAAHC KK +V LG ++L Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124 Query: 82 EPEDTGQRVPVS-HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140 ++GQ++ S PHP Y+ S+DLML++L+ + T V+ + Sbjct: 125 PVYESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIKLNRRIRPTKDVRPIN 173 Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAG 200 + + P+ GT C SGWG+ + + P+ LQC+++ +LS C AY ++ + M CAG Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233 Query: 201 LWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 G+D+C GDSGGP+VCNG LQG+ SWG PCA P +P VYT + + KWI++TI AN Sbjct: 234 D-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292 >gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] Length = 304 Score = 202 bits (513), Expect = 3e-52 Identities = 111/247 (44%), Positives = 141/247 (57%), Gaps = 14/247 (5%) Query: 15 TGAVPLIQS-RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQV 73 T AVP +IVGG+ CE++S P+QV++ S G CGG L+ QWV++AAHC K QV Sbjct: 70 TVAVPFDDDDKIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTRIQV 128 Query: 74 WLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKIT 133 LG HN+ E Q + + HP YN L +D+ML++LS PA I Sbjct: 129 RLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTL-----------DNDIMLIKLSSPAVIN 177 Query: 134 DVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVT 193 V + LPT PA GT C SGWG+ P L+C+ +L+ C +Y K+T Sbjct: 178 ARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKIT 237 Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWI 253 M C G GGKD+C DSGGP+VCNG LQG+ SWG CA +P VYTKV +Y WI Sbjct: 238 NSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWI 296 Query: 254 KDTIAAN 260 KDTIAAN Sbjct: 297 KDTIAAN 303 >gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] Length = 247 Score = 199 bits (505), Expect = 3e-51 Identities = 107/237 (45%), Positives = 136/237 (57%), Gaps = 13/237 (5%) Query: 24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83 +IVGG+ CE++S P+QV++ S G+ CGG L+ QWV++A HC K QV LG HN+ Sbjct: 23 KIVGGYICEENSVPYQVSLNS-GYHFCGGSLISEQWVVSAGHCYKSRIQVRLGEHNIEVL 81 Query: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143 E Q + + HP YN L +D++L++LS PA I V + LPT Sbjct: 82 EGNEQFINAAKIIRHPKYNSRTL-----------DNDILLIKLSSPAVINSRVSAISLPT 130 Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203 PA GT SGWG+ P LQC+ +LS C +Y K+T M C G Sbjct: 131 APPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLE 190 Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 GGKD+C GDSGGP+V NG LQGI SWG CA +P VYTKV +Y WIKDTIAAN Sbjct: 191 GGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIKDTIAAN 246 >gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo sapiens] Length = 253 Score = 197 bits (502), Expect = 6e-51 Identities = 105/254 (41%), Positives = 141/254 (55%), Gaps = 16/254 (6%) Query: 4 LVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTA 63 L+LS+AL T +I+ G C + S PWQVA+ S HCGGVLV+ +WVLTA Sbjct: 12 LLLSLALE---TAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68 Query: 64 AHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLML 123 AHC V LG L + QR+ S SF HP Y+ + +DLML Sbjct: 69 AHCKMNEYTVHLGSDTLGDRR--AQRIKASKSFRHPGYST-----------QTHVNDLML 115 Query: 124 LRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDM 183 ++L+ A+++ +VK + LP++ GTTC SGWG+ + P L CV + L+S Sbjct: 116 VKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQD 175 Query: 184 CARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVY 243 C + Y + + MLCAG+ K+ C GDSGGPLVC G LQG+ SWG PC P P VY Sbjct: 176 CTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVY 235 Query: 244 TKVVHYRKWIKDTI 257 T+V + KWI DT+ Sbjct: 236 TQVCKFTKWINDTM 249 >gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo sapiens] Length = 253 Score = 197 bits (502), Expect = 6e-51 Identities = 105/254 (41%), Positives = 141/254 (55%), Gaps = 16/254 (6%) Query: 4 LVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTA 63 L+LS+AL T +I+ G C + S PWQVA+ S HCGGVLV+ +WVLTA Sbjct: 12 LLLSLALE---TAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68 Query: 64 AHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLML 123 AHC V LG L + QR+ S SF HP Y+ + +DLML Sbjct: 69 AHCKMNEYTVHLGSDTLGDRR--AQRIKASKSFRHPGYST-----------QTHVNDLML 115 Query: 124 LRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDM 183 ++L+ A+++ +VK + LP++ GTTC SGWG+ + P L CV + L+S Sbjct: 116 VKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQD 175 Query: 184 CARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVY 243 C + Y + + MLCAG+ K+ C GDSGGPLVC G LQG+ SWG PC P P VY Sbjct: 176 CTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVY 235 Query: 244 TKVVHYRKWIKDTI 257 T+V + KWI DT+ Sbjct: 236 TQVCKFTKWINDTM 249 >gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo sapiens] Length = 254 Score = 192 bits (488), Expect = 2e-49 Identities = 96/239 (40%), Positives = 137/239 (57%), Gaps = 14/239 (5%) Query: 23 SRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82 S+I+ G +C HSQPWQ A+ C GVLVHPQWVL+AAHC + + + LG H+L Sbjct: 29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88 Query: 83 PEDTG-QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 ++ G Q V S S HP YN LL ++DLML++L E +D ++ + + Sbjct: 89 DQEPGSQMVEASLSVRHPEYNRPLL-----------ANDLMLIKLDESVSESDTIRSISI 137 Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201 +Q P G +C SGWG + P LQCV++ ++S ++C++ Y M CAG Sbjct: 138 ASQCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGG 195 Query: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260 KD+C GDSGGPL+CNG LQG+ S+G PC P VYT + + +WI+ T+ A+ Sbjct: 196 GHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 >gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] Length = 248 Score = 177 bits (450), Expect = 6e-45 Identities = 102/250 (40%), Positives = 131/250 (52%), Gaps = 11/250 (4%) Query: 6 LSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAH 65 LSI L + G +I G EC ++SQPWQV ++ CGGVL+ +WVLTAAH Sbjct: 3 LSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62 Query: 66 CLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLR 125 C V LG H+L + + T Q S HP Y + H+ HDL LLR Sbjct: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHE---------HDLRLLR 113 Query: 126 LSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185 L P ++T V+ L LP GT C+ SGWG P LQC++L ++S+ C Sbjct: 114 LRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCH 173 Query: 186 RAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGP-EPCALPEKPAVYT 244 Y ++T M+CAG G+D C GDSGGPLVC GVLQG+ SWG PC P VYT Sbjct: 174 GVYPGRITSNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYT 232 Query: 245 KVVHYRKWIK 254 + Y WI+ Sbjct: 233 YICKYVDWIR 242 >gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] Length = 254 Score = 171 bits (432), Expect = 8e-43 Identities = 99/242 (40%), Positives = 127/242 (52%), Gaps = 11/242 (4%) Query: 6 LSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAH 65 LSI L + G +I G EC ++SQPWQV ++ CGGVL+ +WVLTAAH Sbjct: 3 LSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62 Query: 66 CLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLR 125 C V LG H+L + + T Q S HP Y + H+ HDL LLR Sbjct: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHE---------HDLRLLR 113 Query: 126 LSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185 L P ++T V+ L LP GT C+ SGWG P LQC++L ++S+ C Sbjct: 114 LRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCH 173 Query: 186 RAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGP-EPCALPEKPAVYT 244 Y ++T M+CAG G+D C GDSGGPLVC GVLQG+ SWG PC P VYT Sbjct: 174 GVYPGRITSNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYT 232 Query: 245 KV 246 + Sbjct: 233 YI 234 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.456 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,919,930 Number of Sequences: 37866 Number of extensions: 587705 Number of successful extensions: 1823 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 170 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 1198 Number of HSP's gapped (non-prelim): 209 length of query: 261 length of database: 18,247,518 effective HSP length: 100 effective length of query: 161 effective length of database: 14,460,918 effective search space: 2328207798 effective search space used: 2328207798 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.