Guide to the Human Genome
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Search of human proteins with 5031829

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
         (261 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]           559   e-160
gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens]          449   e-126
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho...   435   e-122
gi|4504875 kallikrein 1 preproprotein [Homo sapiens]                  363   e-100
gi|71834855 prostate specific antigen isoform 4 preproprotein [H...   355   2e-98
gi|71834857 prostate specific antigen isoform 5 preproprotein [H...   339   1e-93
gi|71834853 prostate specific antigen isoform 3 preproprotein [H...   332   2e-91
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]     231   5e-61
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]          231   5e-61
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]       231   5e-61
gi|11496281 kallikrein 13 precursor [Homo sapiens]                    230   1e-60
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote...   212   3e-55
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei...   212   3e-55
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]                     209   3e-54
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]        209   3e-54
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]           208   4e-54
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]             205   4e-53
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot...   205   4e-53
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]        204   8e-53
gi|91823048 kallikrein 14 preproprotein [Homo sapiens]                203   1e-52
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ...   202   2e-52
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ...   202   2e-52
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa...   202   2e-52
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]       202   3e-52
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]           199   3e-51
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H...   197   6e-51
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho...   197   6e-51
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s...   192   2e-49
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]                    177   6e-45
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]                     171   8e-43

>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
          Length = 261

 Score =  559 bits (1441), Expect = e-160
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV
Sbjct: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
           LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD
Sbjct: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120

Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
           LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS
Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180

Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 240
           NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP
Sbjct: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 240

Query: 241 AVYTKVVHYRKWIKDTIAANP 261
           AVYTKVVHYRKWIKDTIAANP
Sbjct: 241 AVYTKVVHYRKWIKDTIAANP 261


>gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens]
          Length = 223

 Score =  449 bits (1154), Expect = e-126
 Identities = 210/210 (100%), Positives = 210/210 (100%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV
Sbjct: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
           LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD
Sbjct: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120

Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
           LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS
Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180

Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCG 210
           NDMCARAYSEKVTEFMLCAGLWTGGKDTCG
Sbjct: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCG 210


>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
           sapiens]
          Length = 261

 Score =  435 bits (1118), Expect = e-122
 Identities = 201/261 (77%), Positives = 225/261 (86%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MW  V+ + LSV   GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV
Sbjct: 1   MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
           LTAAHC++  S + LGRH+LF PEDTGQ   VSHSFPHPLY+MSLLK++ LRP +DSSHD
Sbjct: 61  LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120

Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
           LMLLRLSEPA++TD VKV+ LPTQEPALGTTCYASGWGSIEPEEFL P+ LQCV LH++S
Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180

Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 240
           ND+CA+ + +KVT+FMLCAG WTGGK TC GDSGGPLVCNGVLQGITSWG EPCALPE+P
Sbjct: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 240

Query: 241 AVYTKVVHYRKWIKDTIAANP 261
           ++YTKVVHYRKWIKDTI ANP
Sbjct: 241 SLYTKVVHYRKWIKDTIVANP 261


>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
          Length = 262

 Score =  363 bits (931), Expect = e-100
 Identities = 172/261 (65%), Positives = 203/261 (77%), Gaps = 1/261 (0%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MW LVL +ALS+G TGA P IQSRIVGGWECE+HSQPWQ A+Y      CGG+LVH QWV
Sbjct: 1   MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
           LTAAHC+  N Q+WLGRHNLF+ E+T Q V VS SFPHP +NMSLL++ + + DED SHD
Sbjct: 61  LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120

Query: 121 LMLLRLSEPA-KITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLL 179
           LMLLRL+EPA  ITD VKV+ LPT+EP +G+TC ASGWGSIEPE F  P  LQCV L +L
Sbjct: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180

Query: 180 SNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEK 239
            ND C +A+ +KVT+FMLC G   GGKDTC GDSGGPL+C+GVLQG+TSWG  PC  P K
Sbjct: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240

Query: 240 PAVYTKVVHYRKWIKDTIAAN 260
           P+V  +V+ Y KWI+DTIA N
Sbjct: 241 PSVAVRVLSYVKWIEDTIAEN 261


>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
           sapiens]
          Length = 218

 Score =  355 bits (912), Expect = 2e-98
 Identities = 172/261 (65%), Positives = 191/261 (73%), Gaps = 43/261 (16%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MW  V+ + LSV   GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV
Sbjct: 1   MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
           LTAAHC++K                                           P +DSSHD
Sbjct: 61  LTAAHCIRK-------------------------------------------PGDDSSHD 77

Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
           LMLLRLSEPA++TD VKV+ LPTQEPALGTTCYASGWGSIEPEEFL P+ LQCV LH++S
Sbjct: 78  LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 137

Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 240
           ND+CA+ + +KVT+FMLCAG WTGGK TC GDSGGPLVCNGVLQGITSWG EPCALPE+P
Sbjct: 138 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 197

Query: 241 AVYTKVVHYRKWIKDTIAANP 261
           ++YTKVVHYRKWIKDTI ANP
Sbjct: 198 SLYTKVVHYRKWIKDTIVANP 218


>gi|71834857 prostate specific antigen isoform 5 preproprotein [Homo
           sapiens]
          Length = 220

 Score =  339 bits (870), Expect = 1e-93
 Identities = 165/261 (63%), Positives = 186/261 (71%), Gaps = 41/261 (15%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MW  V+ + LSV   GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV
Sbjct: 1   MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
           LTAAHC++  S + LGRH+LF PEDTGQ   VSHSFPHPLY+MSLLK++ LRP +DSS  
Sbjct: 61  LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSS-- 118

Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
                                                  IEPEEFL P+ LQCV LH++S
Sbjct: 119 ---------------------------------------IEPEEFLTPKKLQCVDLHVIS 139

Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 240
           ND+CA+ + +KVT+FMLCAG WTGGK TC GDSGGPLVCNGVLQGITSWG EPCALPE+P
Sbjct: 140 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 199

Query: 241 AVYTKVVHYRKWIKDTIAANP 261
           ++YTKVVHYRKWIKDTI ANP
Sbjct: 200 SLYTKVVHYRKWIKDTIVANP 220


>gi|71834853 prostate specific antigen isoform 3 preproprotein [Homo
           sapiens]
          Length = 238

 Score =  332 bits (852), Expect = 2e-91
 Identities = 155/209 (74%), Positives = 176/209 (84%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MW  V+ + LSV   GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV
Sbjct: 1   MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
           LTAAHC++  S + LGRH+LF PEDTGQ   VSHSFPHPLY+MSLLK++ LRP +DSSHD
Sbjct: 61  LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120

Query: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
           LMLLRLSEPA++TD VKV+ LPTQEPALGTTCYASGWGSIEPEEFL P+ LQCV LH++S
Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180

Query: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTC 209
           ND+CA+ + +KVT+FMLCAG WTGGK TC
Sbjct: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTC 209


>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
          Length = 250

 Score =  231 bits (589), Expect = 5e-61
 Identities = 111/256 (43%), Positives = 159/256 (62%), Gaps = 11/256 (4%)

Query: 5   VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAA 64
           ++ +AL+ G  G     ++RI+ G+EC+ HSQPWQ A++      CG  L+ P+W+LTAA
Sbjct: 6   LILLALATGLVGG----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61

Query: 65  HCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124
           HCLK    V LG+HNL + E   Q    + SFPHP +N SL       P++D  +D+ML+
Sbjct: 62  HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 114

Query: 125 RLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184
           +++ P  IT  V+ L L ++    GT+C  SGWGS    +   P +L+C ++ ++ +  C
Sbjct: 115 KMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 174

Query: 185 ARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYT 244
             AY   +T+ M+CA +  GGKD+C GDSGGPLVCN  LQGI SWG +PCA+  KP VYT
Sbjct: 175 ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYT 234

Query: 245 KVVHYRKWIKDTIAAN 260
           KV  Y  WI++T+  N
Sbjct: 235 KVCKYVDWIQETMKNN 250


>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
          Length = 282

 Score =  231 bits (589), Expect = 5e-61
 Identities = 111/256 (43%), Positives = 159/256 (62%), Gaps = 11/256 (4%)

Query: 5   VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAA 64
           ++ +AL+ G  G     ++RI+ G+EC+ HSQPWQ A++      CG  L+ P+W+LTAA
Sbjct: 38  LILLALATGLVGG----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93

Query: 65  HCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124
           HCLK    V LG+HNL + E   Q    + SFPHP +N SL       P++D  +D+ML+
Sbjct: 94  HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 146

Query: 125 RLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184
           +++ P  IT  V+ L L ++    GT+C  SGWGS    +   P +L+C ++ ++ +  C
Sbjct: 147 KMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 206

Query: 185 ARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYT 244
             AY   +T+ M+CA +  GGKD+C GDSGGPLVCN  LQGI SWG +PCA+  KP VYT
Sbjct: 207 ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYT 266

Query: 245 KVVHYRKWIKDTIAAN 260
           KV  Y  WI++T+  N
Sbjct: 267 KVCKYVDWIQETMKNN 282


>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
          Length = 250

 Score =  231 bits (589), Expect = 5e-61
 Identities = 111/256 (43%), Positives = 159/256 (62%), Gaps = 11/256 (4%)

Query: 5   VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAA 64
           ++ +AL+ G  G     ++RI+ G+EC+ HSQPWQ A++      CG  L+ P+W+LTAA
Sbjct: 6   LILLALATGLVGG----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61

Query: 65  HCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124
           HCLK    V LG+HNL + E   Q    + SFPHP +N SL       P++D  +D+ML+
Sbjct: 62  HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 114

Query: 125 RLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184
           +++ P  IT  V+ L L ++    GT+C  SGWGS    +   P +L+C ++ ++ +  C
Sbjct: 115 KMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 174

Query: 185 ARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYT 244
             AY   +T+ M+CA +  GGKD+C GDSGGPLVCN  LQGI SWG +PCA+  KP VYT
Sbjct: 175 ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYT 234

Query: 245 KVVHYRKWIKDTIAAN 260
           KV  Y  WI++T+  N
Sbjct: 235 KVCKYVDWIQETMKNN 250


>gi|11496281 kallikrein 13 precursor [Homo sapiens]
          Length = 277

 Score =  230 bits (586), Expect = 1e-60
 Identities = 123/271 (45%), Positives = 158/271 (58%), Gaps = 23/271 (8%)

Query: 1   MWDLVLSIA-LSVGCTGAVPLIQSRIV----------GGWECEKHSQPWQVAVYSHGWAH 49
           MW L L IA L++  +G V    S+++          GG+ C  HSQPWQ A+   G   
Sbjct: 1   MWPLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLL 60

Query: 50  CGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSL--LK 107
           CGGVLVHP+WVLTAAHCLK+  +V+LG+H L   E   Q   V HS PHP Y  S   L 
Sbjct: 61  CGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLN 120

Query: 108 HQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPAL-GTTCYASGWGSIEPEEFL 166
           H          HD+MLL L  P ++T  ++ L L        GTTC  SGWG+    +  
Sbjct: 121 HD---------HDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVN 171

Query: 167 RPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGI 226
            P++LQC ++ L S++ C + Y  K+T+ MLCAG   GGKD+C GDSGGPLVCN  L GI
Sbjct: 172 YPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGI 231

Query: 227 TSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257
            SWG  PC  P++P VYT+V  Y  WI++TI
Sbjct: 232 VSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262


>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
           [Homo sapiens]
          Length = 244

 Score =  212 bits (539), Expect = 3e-55
 Identities = 106/238 (44%), Positives = 146/238 (61%), Gaps = 13/238 (5%)

Query: 22  QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
           Q+++V G  C+K S P+Q A+Y+ G   CGGVL+HP WVLTAAHC K N QV+LG+HNL 
Sbjct: 19  QNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLR 78

Query: 82  EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141
           + E + ++  V  +  HP Y+ +               D+MLLRL+ PAK++++++ L L
Sbjct: 79  QRESSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAKLSELIQPLPL 127

Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201
                A  T+C+  GWG     +F  P ++QC  +HL+S + C  AY  ++T+ MLCAG 
Sbjct: 128 ERDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGD 185

Query: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259
              GKD+C GDSGGPLVC   L+G+ SWG  PC   EKP VYT V  Y  WI+ TI A
Sbjct: 186 EKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243


>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
           [Homo sapiens]
          Length = 244

 Score =  212 bits (539), Expect = 3e-55
 Identities = 106/238 (44%), Positives = 146/238 (61%), Gaps = 13/238 (5%)

Query: 22  QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
           Q+++V G  C+K S P+Q A+Y+ G   CGGVL+HP WVLTAAHC K N QV+LG+HNL 
Sbjct: 19  QNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLR 78

Query: 82  EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141
           + E + ++  V  +  HP Y+ +               D+MLLRL+ PAK++++++ L L
Sbjct: 79  QRESSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAKLSELIQPLPL 127

Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201
                A  T+C+  GWG     +F  P ++QC  +HL+S + C  AY  ++T+ MLCAG 
Sbjct: 128 ERDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGD 185

Query: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259
              GKD+C GDSGGPLVC   L+G+ SWG  PC   EKP VYT V  Y  WI+ TI A
Sbjct: 186 EKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243


>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
          Length = 305

 Score =  209 bits (531), Expect = 3e-54
 Identities = 105/238 (44%), Positives = 136/238 (57%), Gaps = 9/238 (3%)

Query: 22  QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
           + +++GG EC+ HSQPWQ A++      CGGVLV   WVLTAAHC K    V LG H+L 
Sbjct: 75  EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134

Query: 82  EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141
             +   Q +PV  S PHP YN S +        ED +HDLMLL+L + A +   VK + L
Sbjct: 135 NKDGPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISL 186

Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201
                  G  C  SGWG++       P +L C  + +     C  AY  ++T+ M+CAG 
Sbjct: 187 ADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS 246

Query: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259
            + G DTC GDSGGPLVC+G LQGITSWG +PC   +KP VYT +  Y  WIK  I +
Sbjct: 247 -SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303


>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
          Length = 260

 Score =  209 bits (531), Expect = 3e-54
 Identities = 105/238 (44%), Positives = 136/238 (57%), Gaps = 9/238 (3%)

Query: 22  QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
           + +++GG EC+ HSQPWQ A++      CGGVLV   WVLTAAHC K    V LG H+L 
Sbjct: 30  EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 89

Query: 82  EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141
             +   Q +PV  S PHP YN S +        ED +HDLMLL+L + A +   VK + L
Sbjct: 90  NKDGPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISL 141

Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201
                  G  C  SGWG++       P +L C  + +     C  AY  ++T+ M+CAG 
Sbjct: 142 ADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS 201

Query: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259
            + G DTC GDSGGPLVC+G LQGITSWG +PC   +KP VYT +  Y  WIK  I +
Sbjct: 202 -SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 258


>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
          Length = 247

 Score =  208 bits (529), Expect = 4e-54
 Identities = 108/237 (45%), Positives = 141/237 (59%), Gaps = 13/237 (5%)

Query: 24  RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83
           +IVGG+ CE++S P+QV++ S G+  CGG L++ QWV++A HC K   QV LG HN+   
Sbjct: 23  KIVGGYNCEENSVPYQVSLNS-GYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVL 81

Query: 84  EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143
           E   Q +  +    HP Y+   L           ++D+ML++LS  A I   V  + LPT
Sbjct: 82  EGNEQFINAAKIIRHPQYDRKTL-----------NNDIMLIKLSSRAVINARVSTISLPT 130

Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203
             PA GT C  SGWG+        P  LQC+   +LS   C  +Y  K+T  M C G   
Sbjct: 131 APPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLE 190

Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260
           GGKD+C GDSGGP+VCNG LQG+ SWG + CA   KP VYTKV +Y KWIK+TIAAN
Sbjct: 191 GGKDSCQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAAN 246


>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
          Length = 250

 Score =  205 bits (521), Expect = 4e-53
 Identities = 99/233 (42%), Positives = 139/233 (59%), Gaps = 7/233 (3%)

Query: 23  SRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82
           +R +G  EC  +SQPWQ  ++      CG  L+  +W+LTAAHC K    V LG H+L++
Sbjct: 21  TRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEHHLWK 80

Query: 83  PEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLP 142
            E   Q   V+  FPHP +N  L  +       D + D+ML+RL   A+++  V+ L L 
Sbjct: 81  WEGPEQLFRVTDFFPHPGFNKDLSAN-------DHNDDIMLIRLPRQARLSPAVQPLNLS 133

Query: 143 TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLW 202
               + G  C  SGWG++   + L P +LQC ++ +L N +C  AY   +++ MLCAGLW
Sbjct: 134 QTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLW 193

Query: 203 TGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKD 255
            GG+ +C GDSGGPLVCNG L G+ S G EPC+ P +PAVYT V HY  WI++
Sbjct: 194 EGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQE 246


>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
           [Homo sapiens]
          Length = 256

 Score =  205 bits (521), Expect = 4e-53
 Identities = 113/272 (41%), Positives = 153/272 (56%), Gaps = 28/272 (10%)

Query: 1   MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
           MW L+L+++  +  T A      +++ G EC  HSQPWQVA+Y  G  +CG  L+ P WV
Sbjct: 1   MW-LLLTLSFLLASTAAQD--GDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWV 57

Query: 61  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSH- 119
           L+AAHC  +  +V LG HNL + +   Q    S   PHP Y             E  SH 
Sbjct: 58  LSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRY-------------EARSHR 104

Query: 120 -DLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSI---EPEEFLRPRS----- 170
            D+MLLRL +PA++   V+   LPT+ P  G  C  SGWG +   EP     PRS     
Sbjct: 105 NDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLP 164

Query: 171 --LQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITS 228
             L C ++ ++S+  C ++Y  ++T  M+CAG    G ++C GDSGGPLVC G+LQGI S
Sbjct: 165 DTLHCANISIISDTSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVS 224

Query: 229 WGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260
           WG  PC    KP VYTKV HY +WI++T+  N
Sbjct: 225 WGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256


>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
          Length = 247

 Score =  204 bits (518), Expect = 8e-53
 Identities = 112/250 (44%), Positives = 142/250 (56%), Gaps = 14/250 (5%)

Query: 12  VGCTGAVPLIQS-RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKN 70
           VG   AVP     +IVGG+ CE++S P+QV++ S G   CGG L+  QWV++AAHC K  
Sbjct: 10  VGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTR 68

Query: 71  SQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPA 130
            QV LG HN+   E   Q +  +    HP YN   L            +D+ML++LS PA
Sbjct: 69  IQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTL-----------DNDIMLIKLSSPA 117

Query: 131 KITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190
            I   V  + LPT  PA GT C  SGWG+        P  L+C+   +L+   C  +Y  
Sbjct: 118 VINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPG 177

Query: 191 KVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYR 250
           K+T  M C G   GGKD+C  DSGGP+VCNG LQG+ SWG   CA   +P VYTKV +Y 
Sbjct: 178 KITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYV 236

Query: 251 KWIKDTIAAN 260
            WIKDTIAAN
Sbjct: 237 DWIKDTIAAN 246


>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
          Length = 267

 Score =  203 bits (516), Expect = 1e-52
 Identities = 104/238 (43%), Positives = 143/238 (60%), Gaps = 13/238 (5%)

Query: 22  QSRIVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCLKKNSQVWLGRHN 79
           +++I+GG  C + SQPWQ A+ +       CGG L+  QWV+TAAHC +   QV LG+HN
Sbjct: 38  ENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHN 97

Query: 80  LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139
           L   E T Q + V     HP YN                +DLMLL+L +PA+I   V+ +
Sbjct: 98  LRRWEATQQVLRVVRQVTHPNYN-----------SRTHDNDLMLLQLQQPARIGRAVRPI 146

Query: 140 GLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCA 199
            +     + GT+C  SGWG+I       P SLQCV++++  +++C +AY   +T  M+CA
Sbjct: 147 EVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCA 206

Query: 200 GLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257
           G+  GGKD+C GDSGGPLVC G LQG+ SWG E CALP  P VYT +  YR WI++T+
Sbjct: 207 GVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETM 264


>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  202 bits (514), Expect = 2e-52
 Identities = 102/240 (42%), Positives = 147/240 (61%), Gaps = 14/240 (5%)

Query: 23  SRIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
           SRI+ G +C+ H+QPWQ A+       +CG VLVHPQW+LTAAHC KK  +V LG ++L 
Sbjct: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124

Query: 82  EPEDTGQRVPVS-HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140
              ++GQ++     S PHP Y+               S+DLML++L+   + T  V+ + 
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIKLNRRIRPTKDVRPIN 173

Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAG 200
           + +  P+ GT C  SGWG+ +  +   P+ LQC+++ +LS   C  AY  ++ + M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233

Query: 201 LWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260
               G+D+C GDSGGP+VCNG LQG+ SWG  PCA P +P VYT +  + KWI++TI AN
Sbjct: 234 D-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292


>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  202 bits (514), Expect = 2e-52
 Identities = 102/240 (42%), Positives = 147/240 (61%), Gaps = 14/240 (5%)

Query: 23  SRIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
           SRI+ G +C+ H+QPWQ A+       +CG VLVHPQW+LTAAHC KK  +V LG ++L 
Sbjct: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124

Query: 82  EPEDTGQRVPVS-HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140
              ++GQ++     S PHP Y+               S+DLML++L+   + T  V+ + 
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIKLNRRIRPTKDVRPIN 173

Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAG 200
           + +  P+ GT C  SGWG+ +  +   P+ LQC+++ +LS   C  AY  ++ + M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233

Query: 201 LWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260
               G+D+C GDSGGP+VCNG LQG+ SWG  PCA P +P VYT +  + KWI++TI AN
Sbjct: 234 D-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292


>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  202 bits (514), Expect = 2e-52
 Identities = 102/240 (42%), Positives = 147/240 (61%), Gaps = 14/240 (5%)

Query: 23  SRIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
           SRI+ G +C+ H+QPWQ A+       +CG VLVHPQW+LTAAHC KK  +V LG ++L 
Sbjct: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124

Query: 82  EPEDTGQRVPVS-HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140
              ++GQ++     S PHP Y+               S+DLML++L+   + T  V+ + 
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIKLNRRIRPTKDVRPIN 173

Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAG 200
           + +  P+ GT C  SGWG+ +  +   P+ LQC+++ +LS   C  AY  ++ + M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233

Query: 201 LWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260
               G+D+C GDSGGP+VCNG LQG+ SWG  PCA P +P VYT +  + KWI++TI AN
Sbjct: 234 D-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292


>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
          Length = 304

 Score =  202 bits (513), Expect = 3e-52
 Identities = 111/247 (44%), Positives = 141/247 (57%), Gaps = 14/247 (5%)

Query: 15  TGAVPLIQS-RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQV 73
           T AVP     +IVGG+ CE++S P+QV++ S G   CGG L+  QWV++AAHC K   QV
Sbjct: 70  TVAVPFDDDDKIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTRIQV 128

Query: 74  WLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKIT 133
            LG HN+   E   Q +  +    HP YN   L            +D+ML++LS PA I 
Sbjct: 129 RLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTL-----------DNDIMLIKLSSPAVIN 177

Query: 134 DVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVT 193
             V  + LPT  PA GT C  SGWG+        P  L+C+   +L+   C  +Y  K+T
Sbjct: 178 ARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKIT 237

Query: 194 EFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWI 253
             M C G   GGKD+C  DSGGP+VCNG LQG+ SWG   CA   +P VYTKV +Y  WI
Sbjct: 238 NSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWI 296

Query: 254 KDTIAAN 260
           KDTIAAN
Sbjct: 297 KDTIAAN 303


>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
          Length = 247

 Score =  199 bits (505), Expect = 3e-51
 Identities = 107/237 (45%), Positives = 136/237 (57%), Gaps = 13/237 (5%)

Query: 24  RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83
           +IVGG+ CE++S P+QV++ S G+  CGG L+  QWV++A HC K   QV LG HN+   
Sbjct: 23  KIVGGYICEENSVPYQVSLNS-GYHFCGGSLISEQWVVSAGHCYKSRIQVRLGEHNIEVL 81

Query: 84  EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143
           E   Q +  +    HP YN   L            +D++L++LS PA I   V  + LPT
Sbjct: 82  EGNEQFINAAKIIRHPKYNSRTL-----------DNDILLIKLSSPAVINSRVSAISLPT 130

Query: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203
             PA GT    SGWG+        P  LQC+   +LS   C  +Y  K+T  M C G   
Sbjct: 131 APPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLE 190

Query: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260
           GGKD+C GDSGGP+V NG LQGI SWG   CA   +P VYTKV +Y  WIKDTIAAN
Sbjct: 191 GGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIKDTIAAN 246


>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
           sapiens]
          Length = 253

 Score =  197 bits (502), Expect = 6e-51
 Identities = 105/254 (41%), Positives = 141/254 (55%), Gaps = 16/254 (6%)

Query: 4   LVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTA 63
           L+LS+AL    T        +I+ G  C + S PWQVA+ S    HCGGVLV+ +WVLTA
Sbjct: 12  LLLSLALE---TAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68

Query: 64  AHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLML 123
           AHC      V LG   L +     QR+  S SF HP Y+            +   +DLML
Sbjct: 69  AHCKMNEYTVHLGSDTLGDRR--AQRIKASKSFRHPGYST-----------QTHVNDLML 115

Query: 124 LRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDM 183
           ++L+  A+++ +VK + LP++    GTTC  SGWG+    +   P  L CV + L+S   
Sbjct: 116 VKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQD 175

Query: 184 CARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVY 243
           C + Y + +   MLCAG+    K+ C GDSGGPLVC G LQG+ SWG  PC  P  P VY
Sbjct: 176 CTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVY 235

Query: 244 TKVVHYRKWIKDTI 257
           T+V  + KWI DT+
Sbjct: 236 TQVCKFTKWINDTM 249


>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
           sapiens]
          Length = 253

 Score =  197 bits (502), Expect = 6e-51
 Identities = 105/254 (41%), Positives = 141/254 (55%), Gaps = 16/254 (6%)

Query: 4   LVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTA 63
           L+LS+AL    T        +I+ G  C + S PWQVA+ S    HCGGVLV+ +WVLTA
Sbjct: 12  LLLSLALE---TAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68

Query: 64  AHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLML 123
           AHC      V LG   L +     QR+  S SF HP Y+            +   +DLML
Sbjct: 69  AHCKMNEYTVHLGSDTLGDRR--AQRIKASKSFRHPGYST-----------QTHVNDLML 115

Query: 124 LRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDM 183
           ++L+  A+++ +VK + LP++    GTTC  SGWG+    +   P  L CV + L+S   
Sbjct: 116 VKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQD 175

Query: 184 CARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVY 243
           C + Y + +   MLCAG+    K+ C GDSGGPLVC G LQG+ SWG  PC  P  P VY
Sbjct: 176 CTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVY 235

Query: 244 TKVVHYRKWIKDTI 257
           T+V  + KWI DT+
Sbjct: 236 TQVCKFTKWINDTM 249


>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
           sapiens]
          Length = 254

 Score =  192 bits (488), Expect = 2e-49
 Identities = 96/239 (40%), Positives = 137/239 (57%), Gaps = 14/239 (5%)

Query: 23  SRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82
           S+I+ G +C  HSQPWQ A+       C GVLVHPQWVL+AAHC + +  + LG H+L  
Sbjct: 29  SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88

Query: 83  PEDTG-QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141
            ++ G Q V  S S  HP YN  LL           ++DLML++L E    +D ++ + +
Sbjct: 89  DQEPGSQMVEASLSVRHPEYNRPLL-----------ANDLMLIKLDESVSESDTIRSISI 137

Query: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201
            +Q P  G +C  SGWG +       P  LQCV++ ++S ++C++ Y       M CAG 
Sbjct: 138 ASQCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGG 195

Query: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260
               KD+C GDSGGPL+CNG LQG+ S+G  PC     P VYT +  + +WI+ T+ A+
Sbjct: 196 GHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254


>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
          Length = 248

 Score =  177 bits (450), Expect = 6e-45
 Identities = 102/250 (40%), Positives = 131/250 (52%), Gaps = 11/250 (4%)

Query: 6   LSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAH 65
           LSI L +   G       +I  G EC ++SQPWQV ++      CGGVL+  +WVLTAAH
Sbjct: 3   LSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62

Query: 66  CLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLR 125
           C      V LG H+L + + T Q      S  HP Y  +   H+         HDL LLR
Sbjct: 63  CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHE---------HDLRLLR 113

Query: 126 LSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185
           L  P ++T  V+ L LP      GT C+ SGWG         P  LQC++L ++S+  C 
Sbjct: 114 LRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCH 173

Query: 186 RAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGP-EPCALPEKPAVYT 244
             Y  ++T  M+CAG    G+D C GDSGGPLVC GVLQG+ SWG   PC     P VYT
Sbjct: 174 GVYPGRITSNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYT 232

Query: 245 KVVHYRKWIK 254
            +  Y  WI+
Sbjct: 233 YICKYVDWIR 242


>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
          Length = 254

 Score =  171 bits (432), Expect = 8e-43
 Identities = 99/242 (40%), Positives = 127/242 (52%), Gaps = 11/242 (4%)

Query: 6   LSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAH 65
           LSI L +   G       +I  G EC ++SQPWQV ++      CGGVL+  +WVLTAAH
Sbjct: 3   LSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62

Query: 66  CLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLR 125
           C      V LG H+L + + T Q      S  HP Y  +   H+         HDL LLR
Sbjct: 63  CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHE---------HDLRLLR 113

Query: 126 LSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185
           L  P ++T  V+ L LP      GT C+ SGWG         P  LQC++L ++S+  C 
Sbjct: 114 LRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCH 173

Query: 186 RAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGP-EPCALPEKPAVYT 244
             Y  ++T  M+CAG    G+D C GDSGGPLVC GVLQG+ SWG   PC     P VYT
Sbjct: 174 GVYPGRITSNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYT 232

Query: 245 KV 246
            +
Sbjct: 233 YI 234


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.456 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,919,930
Number of Sequences: 37866
Number of extensions: 587705
Number of successful extensions: 1823
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 170
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1198
Number of HSP's gapped (non-prelim): 209
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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