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Search of human proteins with 5031621
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5031621 calcitonin receptor-like [Homo sapiens]
(461 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5031621 calcitonin receptor-like [Homo sapiens] 961 0.0
gi|4502547 calcitonin receptor [Homo sapiens] 556 e-158
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens] 227 2e-59
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap... 202 5e-52
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens] 198 1e-50
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens] 195 6e-50
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens] 189 3e-48
gi|114205383 secretin receptor precursor [Homo sapiens] 189 6e-48
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2... 187 1e-47
gi|4503947 glucagon receptor [Homo sapiens] 187 1e-47
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar... 185 7e-47
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi... 185 9e-47
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens] 184 1e-46
gi|223717978 corticotropin releasing hormone receptor 1 isoform ... 181 2e-45
gi|223717971 corticotropin releasing hormone receptor 1 isoform ... 172 6e-43
gi|223717985 corticotropin releasing hormone receptor 1 isoform ... 161 1e-39
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens] 155 7e-38
gi|58530851 growth hormone releasing hormone receptor isoform a ... 137 2e-32
gi|58530853 growth hormone releasing hormone receptor isoform b ... 105 7e-23
gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 97 3e-20
gi|163792198 latrophilin 3 precursor [Homo sapiens] 81 2e-15
gi|148806925 EGF, latrophilin and seven transmembrane domain con... 79 7e-15
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 78 1e-14
gi|40807489 egf-like module containing, mucin-like, hormone rece... 77 3e-14
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] 75 1e-13
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] 75 1e-13
gi|240120161 G protein-coupled receptor 144 [Homo sapiens] 75 2e-13
gi|133930786 egf-like module-containing mucin-like receptor 3 [H... 74 3e-13
gi|6912464 latrophilin 2 precursor [Homo sapiens] 72 1e-12
gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapi... 66 6e-11
>gi|5031621 calcitonin receptor-like [Homo sapiens]
Length = 461
Score = 961 bits (2483), Expect = 0.0
Identities = 461/461 (100%), Positives = 461/461 (100%)
Query: 1 MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQA 60
MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQA
Sbjct: 1 MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQA 60
Query: 61 EGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRT 120
EGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRT
Sbjct: 61 EGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRT 120
Query: 121 WTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNL 180
WTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNL
Sbjct: 121 WTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNL 180
Query: 181 FFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTL 240
FFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTL
Sbjct: 181 FFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTL 240
Query: 241 IVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICA 300
IVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICA
Sbjct: 241 IVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICA 300
Query: 301 ALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKI 360
ALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKI
Sbjct: 301 ALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKI 360
Query: 361 AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSAS 420
AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSAS
Sbjct: 361 AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSAS 420
Query: 421 YTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN 461
YTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
Sbjct: 421 YTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN 461
>gi|4502547 calcitonin receptor [Homo sapiens]
Length = 474
Score = 556 bits (1434), Expect = e-158
Identities = 257/445 (57%), Positives = 321/445 (72%), Gaps = 9/445 (2%)
Query: 4 KCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPI 57
+C FL+L LP F +E P + V R K+M AQY+CY ++ Q P
Sbjct: 8 RCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMDAQYKCYDRMQQLPA 64
Query: 58 QQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPAS 117
Q EG YCNRTWDGWLCW+D AG S Q CPDYF DFDPSEKVTK CD+ G WF+HP +
Sbjct: 65 YQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPEN 124
Query: 118 NRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLH 177
NRTW+NYT CN T EK+K A L+YL I+GH LSI +L+ISLGIF +F+SL CQR+TLH
Sbjct: 125 NRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLH 184
Query: 178 KNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYL 237
KN+F +++ NS++ IIHL V N LV +PVSCK+ F H Y+M CNYFWMLCEGIYL
Sbjct: 185 KNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYL 244
Query: 238 HTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGP 297
HTLIVVAVF EKQ L WYY LGWGFPL+P IHAI R++Y+NDNCW+S +THLLYIIHGP
Sbjct: 245 HTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYIIHGP 304
Query: 298 ICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPE 357
+ AAL+VN FFLLNIVRVL+TK++ TH+AES++Y+KAV+AT+ILVPLLGI+FV+ PWRP
Sbjct: 305 VMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPS 364
Query: 358 GKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALR 417
K+ ++YDY+MH L+HFQG V+TI+CF N EVQ ++R W Q+KIQ+ + + R
Sbjct: 365 NKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNR 424
Query: 418 SASYTVSTISDGPGYSHDCPSEHLN 442
SA + G + C E N
Sbjct: 425 SARAAAAAAEAGDIPIYICHQELRN 449
>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
Length = 593
Score = 227 bits (579), Expect = 2e-59
Identities = 132/404 (32%), Positives = 205/404 (50%), Gaps = 43/404 (10%)
Query: 65 CNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNY 124
C WD LCW A G CPDY DF+ + CD++G+W P NRTW NY
Sbjct: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANY 167
Query: 125 TQC-----NVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKN 179
++C N +V L + Y +G+ +S+ASL +++ I YF+ L C R +H +
Sbjct: 168 SECVKFLTNETREREVFDRLGMIYT--VGYSVSLASLTVAVLILAYFRRLHCTRNYIHMH 225
Query: 180 LFFSFVCNSVVTII--------------------HLTAVANNQ---ALVATNPVSCKVSQ 216
LF SF+ +V + L A+A A A C+V+
Sbjct: 226 LFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAV 285
Query: 217 FIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSL 276
LY + NY+W+L EG+YLH+LI +A F+EK++L + GWG P + + R+
Sbjct: 286 TFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRAT 345
Query: 277 YYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNL---YMK 333
N CW S + +II PI A++++N +NIVRVL TKL+ T+ + Y K
Sbjct: 346 LANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRK 405
Query: 334 AVRATLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHILM---HFQGLLVSTIFCFFNGE 390
+++TL+L+PL G+ +++ P +++ ++ MH M FQG V+ I+CF NGE
Sbjct: 406 LLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGE 465
Query: 391 VQAILRRNWNQYKIQFGNSFSNSEALRSASYTVSTISDGPGYSH 434
VQA ++++W+++ + F S+SY S GP SH
Sbjct: 466 VQAEIKKSWSRWTLAL--DFKRKARSGSSSY-----SYGPMVSH 502
>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
sapiens]
Length = 411
Score = 202 bits (514), Expect = 5e-52
Identities = 120/351 (34%), Positives = 188/351 (53%), Gaps = 22/351 (6%)
Query: 64 YCNRTWDG-WLCWNDVAAGTESMQLCPDYFQD--FDPSEKVTKICDQDGNWFRHPASNRT 120
YCN T D CW AAG + CP+YF ++ + + C ++G W +
Sbjct: 39 YCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTW-------AS 91
Query: 121 WTNYTQCNVNTHEKVKTALNLFY-----LTIIGHGLSIASLLISLGIFFYFKSLSCQRIT 175
NY+QC +K + +L Y + +GH +S+A+L+ + +F +S+ C R
Sbjct: 92 KINYSQCEPILDDKQRK-YDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNV 150
Query: 176 LHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGI 235
+H NL +F+ +V+ + L V + + +N V C+ I Y + N+FWM EG
Sbjct: 151 IHWNLITTFILRNVMWFL-LQLV--DHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGC 207
Query: 236 YLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLL--YI 293
YLHT IV+ E+ + F+GW P AI + Y N+ CW + L YI
Sbjct: 208 YLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVDYI 267
Query: 294 IHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIP 353
GPI LL+N FL NIVR+L+TKL+ + +E+ Y KAV+ATL+L+PLLGI ++L
Sbjct: 268 YQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF 327
Query: 354 WRP-EGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYK 403
P E +++ ++ Y L FQG VS +CFFNGEV++ +R+ W++++
Sbjct: 328 VNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRWQ 378
>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
Length = 550
Score = 198 bits (503), Expect = 1e-50
Identities = 117/418 (27%), Positives = 201/418 (48%), Gaps = 35/418 (8%)
Query: 18 ILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWND 77
+L A+L+ +I+ + ++ A+ +C I +Q+ EG C WDG +CW
Sbjct: 20 LLARAQLDSDGTITIEEQIVL--VLKAKVQCELNITAQ-LQEGEG-NCFPEWDGLICWPR 75
Query: 78 VAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKT 137
G S CP Y DF+ + C+ +G W + N+TW NY+ C +
Sbjct: 76 GTVGKISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISI 135
Query: 138 ALNLFY-----LTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTI 192
F+ + +G+ +S SL +++ I YF+ L C R +H +LF SF+ +
Sbjct: 136 GKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIF 195
Query: 193 I-------HLTAVANNQALVATNP--------------VSCKVSQFIHLYLMGCNYFWML 231
+ H+ ++ +P + CK++ + +Y + NY+W+L
Sbjct: 196 VKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWIL 255
Query: 232 CEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLL 291
EG+YLH LI VA F++ ++L + +GWGFP A+AR+ + CW S +
Sbjct: 256 VEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARATLADARCWELSAGDIK 315
Query: 292 YIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNL---YMKAVRATLILVPLLGIE 348
+I PI AA+ +N LN VRVL TK+ T+ + Y K ++TL+LV + G+
Sbjct: 316 WIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVH 375
Query: 349 FVLIPWRPEG--KIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKI 404
+++ P + E+ + FQG VS I+C+ NGEVQA +++ W+++ +
Sbjct: 376 YIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRWNL 433
>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
Length = 457
Score = 195 bits (496), Expect = 6e-50
Identities = 108/368 (29%), Positives = 192/368 (52%), Gaps = 16/368 (4%)
Query: 49 YQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSE--KVTKICD 106
+++ +++ + E + C++ WD CW G + CP F+ F + V++ C
Sbjct: 47 HKQCLEEAQLENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCT 106
Query: 107 QDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTI-----IGHGLSIASLLISLG 161
+G P + E+ +FY ++ IG+GLS+A+LL++
Sbjct: 107 DEGWTHLEPGPYPIACGLDDKAASLDEQQ----TMFYGSVKTGYTIGYGLSLATLLVATA 162
Query: 162 IFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAV--ANNQALVATNPVSCKVSQFIH 219
I F+ L C R +H +LF SF+ + I A+ + + V CK +
Sbjct: 163 ILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFF 222
Query: 220 LYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYN 279
Y + N+FW+L EG+YL+TL+ V+ F+E+++ Y +GWG P + IAR + +
Sbjct: 223 QYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFED 282
Query: 280 DNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKV--THQAESNLYMKAVRA 337
CW + ++ L +II GPI ++LVN + I+R+L+ KL+ +++S+ Y + R+
Sbjct: 283 YGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARS 342
Query: 338 TLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRR 397
TL+L+PL G+ +++ + P+ EV ++ FQG +V+ ++CF NGEVQA LRR
Sbjct: 343 TLLLIPLFGVHYIMFAFFPD-NFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRR 401
Query: 398 NWNQYKIQ 405
W ++ +Q
Sbjct: 402 KWRRWHLQ 409
>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
Length = 466
Score = 189 bits (481), Expect = 3e-48
Identities = 126/409 (30%), Positives = 204/409 (49%), Gaps = 50/409 (12%)
Query: 32 IQLGVTRNKIMTA-----QYECYQKIMQDPIQQAE---GVYCNRTWDGWLCWNDVAAGTE 83
+Q T +K TA ++E Y++ Q+ + AE G+ CN ++D ++CW+ A
Sbjct: 20 LQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNAT 79
Query: 84 SMQLCPDY--FQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALN- 140
+ CP Y + + V + C DG W W ++TQC EK + L+
Sbjct: 80 ARASCPWYLPWHHHVAAGFVLRQCGSDGQW-------GLWRDHTQCE--NPEKNEAFLDQ 130
Query: 141 ------LFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIH 194
L + +G+ LS+A+LL++L I F+ L C R +H NLF SF+ + +
Sbjct: 131 RLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSR 190
Query: 195 LTAVAN------NQALVATNPV--SCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVF 246
+ +QAL N +C+ +Q + Y +G NY W+L EG+YLH+L+V+
Sbjct: 191 DRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGG 250
Query: 247 AEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLL-YIIHGPICAALLVN 305
+E+ H +Y LGWG P + I R LY N CW ++ + +II PI +L+N
Sbjct: 251 SEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRTPILMTILIN 310
Query: 306 LFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGI-EFVLIPWRPE------- 357
+ I+ +L++KL+ + ++ R+TL LVPLLG+ E V P E
Sbjct: 311 FLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALR 370
Query: 358 -GKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQ 405
K+ E++ L FQG LVS ++CF N EVQ+ +RR W+ +++
Sbjct: 371 FAKLGFEIF------LSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLR 413
>gi|114205383 secretin receptor precursor [Homo sapiens]
Length = 440
Score = 189 bits (479), Expect = 6e-48
Identities = 106/352 (30%), Positives = 181/352 (51%), Gaps = 19/352 (5%)
Query: 65 CNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSE-KVTKICDQDGNWFRHPASNRTWTN 123
C WD CW G CP + + + + C QDG P N
Sbjct: 66 CEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPNLA--- 122
Query: 124 YTQCNVNTHEKVKTALNLFYLTI-----IGHGLSIASLLISLGIFFYFKSLSCQRITLHK 178
C VN ++ + + L + +G+ S+ LL++LGI F+ L C R +H
Sbjct: 123 ---CGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHM 179
Query: 179 NLFFSFVCNSVVTIIHLTAVANNQALVATNP--VSCKVSQFIHLYLMGCNYFWMLCEGIY 236
+LF SF+ ++ I + ++ + + CK+ + Y + NY W+L EG+Y
Sbjct: 180 HLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLY 239
Query: 237 LHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCW-ISSDTHLLYIIH 295
LHTL+ ++ F+E+++L + GWG P I + AIAR + CW I+++ + +II
Sbjct: 240 LHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIR 299
Query: 296 GPICAALLVNLFFLLNIVRVLITKLKV--THQAESNLYMKAVRATLILVPLLGIEFVLIP 353
GP+ ++L+N +NI+R+L+ KL+ T E + Y + R+TL+L+PL GI +++
Sbjct: 300 GPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFA 359
Query: 354 WRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQ 405
+ PE A E+ + L FQGL+V+ ++CF NGEVQ +++ W Q+ ++
Sbjct: 360 FSPED--AMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLR 409
>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
[Homo sapiens]
Length = 415
Score = 187 bits (476), Expect = 1e-47
Identities = 111/352 (31%), Positives = 184/352 (52%), Gaps = 20/352 (5%)
Query: 62 GVYCNRTWDG-WLCWNDVAAGTESMQLCPDYFQD--FDPSEKVTKICDQDGNWFRHPASN 118
G+ CN + D CW AG ++ CP +F ++ + + C +G+W
Sbjct: 41 GLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAAR---- 96
Query: 119 RTWTNYTQCNVNTHEKVKTALNLFYLTII---GHGLSIASLLISLGIFFYFKSLSCQRIT 175
NY++C +E+ K+ ++ II GH +S+ +LL++ +F +S+ C R
Sbjct: 97 ---VNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNI 153
Query: 176 LHKNLFFSFVC-NSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEG 234
+H NL +F+ N+ ++ LT + + +N C++ + Y N+FWM EG
Sbjct: 154 IHWNLISAFILRNATWFVVQLTM---SPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEG 210
Query: 235 IYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISS--DTHLLY 292
YLHT IV+ ++ + +GWG P AI + Y N+ CW + Y
Sbjct: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270
Query: 293 IIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLI 352
I GP+ LL+N FL NIVR+L+TKL+ + +E+ Y KAV+ATL+L+PLLGI ++L
Sbjct: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLF 330
Query: 353 PWRP-EGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYK 403
P E +++ V+ Y L FQG VS +CF N EV++ +R+ W++++
Sbjct: 331 FVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQ 382
>gi|4503947 glucagon receptor [Homo sapiens]
Length = 477
Score = 187 bits (476), Expect = 1e-47
Identities = 117/369 (31%), Positives = 188/369 (50%), Gaps = 35/369 (9%)
Query: 65 CNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEK--VTKICDQDGNWFRHPASNRTWT 122
CNRT+D + CW D A T + CP Y + V K C DG W R P + W
Sbjct: 58 CNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRG-QPWR 116
Query: 123 NYTQCNVNTHE--------KVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRI 174
+ +QC ++ E K+ ++ + Y +G+ LS+ +LL++L I L C R
Sbjct: 117 DASQCQMDGEEIEVQKEVAKMYSSFQVMYT--VGYSLSLGALLLALAILGGLSKLHCTRN 174
Query: 175 TLHKNLFFSFV--CNSVVTIIHLTAVANNQALVATNPVS----------CKVSQFIHLYL 222
+H NLF SFV +SV+ I L +Q + VS C+V+ Y
Sbjct: 175 AIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYG 234
Query: 223 MGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNC 282
+ NY W+L EG+YLH L+ +A E+ Y +GWG P++ A+ + L+ N C
Sbjct: 235 IVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQC 294
Query: 283 WISSDT-HLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLIL 341
W S+D +I+ P+ A+L+N F + IV++L+ KL+ ++ + ++TL L
Sbjct: 295 WTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTL 354
Query: 342 VPLLGIEFVLIPW----RPEGKI--AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAIL 395
+PLLG+ V+ + +G + A+ +D L FQGLLV+ ++CF N EVQ+ L
Sbjct: 355 IPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDL---FLSSFQGLLVAVLYCFLNKEVQSEL 411
Query: 396 RRNWNQYKI 404
RR W+++++
Sbjct: 412 RRRWHRWRL 420
>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
receptor type I precursor [Homo sapiens]
Length = 468
Score = 185 bits (470), Expect = 7e-47
Identities = 108/379 (28%), Positives = 181/379 (47%), Gaps = 51/379 (13%)
Query: 65 CNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEK------------------------ 100
C WD CW G + CP+ F+ F+P +
Sbjct: 54 CPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGV 113
Query: 101 VTKICDQDGNW---FRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTI-----IGHGLS 152
V++ C +DG W F H + C + +E + +YL++ +G+ S
Sbjct: 114 VSRNCTEDG-WSEPFPH--------YFDACGFDEYESETGDQDYYYLSVKALYTVGYSTS 164
Query: 153 IASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIH----LTAVANNQALVATN 208
+ +L ++ I F+ L C R +H NLF SF+ ++ I +N ++T
Sbjct: 165 LVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFIST- 223
Query: 209 PVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPAC 268
V CK Y + NYFW+ EG+YL TL+V F E+++ WY +GWG P +
Sbjct: 224 -VECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVT 282
Query: 269 IHAIARSLYYNDNCWISSD-THLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQA- 326
+ A R + + CW +D T L ++I GP+ +++VN + I+ +L+ KL+
Sbjct: 283 VWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGG 342
Query: 327 -ESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFC 385
ES++Y++ R+TL+L+PL GI + + + PE E + + L FQG +V+ ++C
Sbjct: 343 NESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELG-LGSFQGFVVAVLYC 401
Query: 386 FFNGEVQAILRRNWNQYKI 404
F NGEVQA ++R W +K+
Sbjct: 402 FLNGEVQAEIKRKWRSWKV 420
>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
sapiens]
Length = 553
Score = 185 bits (469), Expect = 9e-47
Identities = 111/383 (28%), Positives = 194/383 (50%), Gaps = 29/383 (7%)
Query: 44 AQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDF--DPSEKV 101
AQY+ Q ++D +++ G++CN T+D ++CW + G S+ CP Y + + S +
Sbjct: 77 AQYK--QACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVP-CPSYLPWWSEESSGRA 133
Query: 102 TKICDQDGNWFRHPASNRTWTNYTQCNVNTHEK-------VKTALNLFYLTIIGHGLSIA 154
+ C G W + W + ++C+ N K + + L L Y +G+ S+
Sbjct: 134 YRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYT--VGYSFSLI 191
Query: 155 SLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNP----- 209
SL ++L + + + L C R +H NLF SF+ ++ ++ N+ + N
Sbjct: 192 SLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMS 251
Query: 210 ------VSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFP 263
SC+ Q + Y +G NY W+L EG+YLHTL+ V E++ Y LGW FP
Sbjct: 252 YLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFP 311
Query: 264 LIPACIHAIARSLYYNDNCWISS-DTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKV 322
++ AR+ N CW ++ + + +II GP+ + VN F L I+++LI+KLK
Sbjct: 312 VLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKA 371
Query: 323 THQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKI---AEEVYDYIMHILMHFQGLL 379
+ + ++TL+L+PLLG+ +L + + ++ A+ + +I L F G L
Sbjct: 372 HQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFL 431
Query: 380 VSTIFCFFNGEVQAILRRNWNQY 402
V+ + F NGEV+A LR+ W ++
Sbjct: 432 VALQYGFANGEVKAELRKYWVRF 454
>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
Length = 463
Score = 184 bits (468), Expect = 1e-46
Identities = 116/421 (27%), Positives = 211/421 (50%), Gaps = 25/421 (5%)
Query: 31 SIQLGVTRNKIMTAQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPD 90
++ L T K + +C + + +DP A ++CNRT+D + CW D G+ CP
Sbjct: 29 TVSLWETVQKWREYRRQCQRSLTEDP-PPATDLFCNRTFDEYACWPDGEPGSFVNVSCPW 87
Query: 91 Y--FQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVNTH-EKVKTALNLFYLTII 147
Y + P V + C +G W + S+ W + ++C + E+ L +L II
Sbjct: 88 YLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYII 147
Query: 148 ---GHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTII--------HLT 196
G+ LS ++L+I+ I F+ L C R +H NLF SF+ ++ I + T
Sbjct: 148 YTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYST 207
Query: 197 AVANNQ---ALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLM 253
A +Q L + +SC++ + Y + NY+W+L EG+YL+TL+ +V +E+
Sbjct: 208 AAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFR 267
Query: 254 WYYFLGWGFPLIPACIHAIARSLYYNDNCWI-SSDTHLLYIIHGPICAALLVNLFFLLNI 312
Y +GWG PL+ I + LY ++ CW +S+ + II PI A+ VN + +
Sbjct: 268 LYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRV 327
Query: 313 VRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHI- 371
+ ++++KLK ++++ + ++TL L+PLLG V+ + + + A +I
Sbjct: 328 ICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMD-EHARGTLRFIKLFT 386
Query: 372 ---LMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSASYTVSTISD 428
FQGL+V+ ++CF N EVQ R++W +++++ + +++ S++S
Sbjct: 387 ELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLH-IQRDSSMKPLKCPTSSLSS 445
Query: 429 G 429
G
Sbjct: 446 G 446
>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
[Homo sapiens]
Length = 375
Score = 181 bits (458), Expect = 2e-45
Identities = 101/304 (33%), Positives = 166/304 (54%), Gaps = 13/304 (4%)
Query: 110 NWFRHPASNRTWT---NYTQCNVNTHEKVKTALNLFYLTII---GHGLSIASLLISLGIF 163
N +R +N +W NY++C +E+ K+ ++ II GH +S+ +LL++ +F
Sbjct: 42 NGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLF 101
Query: 164 FYFKSLSCQRITLHKNLFFSFVC-NSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYL 222
+S+ C R +H NL +F+ N+ ++ LT + + +N C++ + Y
Sbjct: 102 LRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTM---SPEVHQSNVGWCRLVTAAYNYF 158
Query: 223 MGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNC 282
N+FWM EG YLHT IV+ ++ + +GWG P AI + Y N+ C
Sbjct: 159 HVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKC 218
Query: 283 WISS--DTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLI 340
W + YI GP+ LL+N FL NIVR+L+TKL+ + +E+ Y KAV+ATL+
Sbjct: 219 WFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLV 278
Query: 341 LVPLLGIEFVLIPWRP-EGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNW 399
L+PLLGI ++L P E +++ V+ Y L FQG VS +CF N EV++ +R+ W
Sbjct: 279 LLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRW 338
Query: 400 NQYK 403
++++
Sbjct: 339 HRWQ 342
>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
[Homo sapiens]
Length = 444
Score = 172 bits (436), Expect = 6e-43
Identities = 111/381 (29%), Positives = 184/381 (48%), Gaps = 49/381 (12%)
Query: 62 GVYCNRTWDG-WLCWNDVAAGTESMQLCPDYFQD--FDPSEKVTKICDQDGNWFRHPASN 118
G+ CN + D CW AG ++ CP +F ++ + + C +G+W
Sbjct: 41 GLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAAR---- 96
Query: 119 RTWTNYTQCNVNTHEKVKTALNLFYLTII---GHGLSIASLLISLGIFFYFK-------- 167
NY++C +E+ K+ ++ II GH +S+ +LL++ +F +
Sbjct: 97 ---VNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWGD 153
Query: 168 ---------------------SLSCQRITLHKNLFFSFVC-NSVVTIIHLTAVANNQALV 205
S+ C R +H NL +F+ N+ ++ LT + +
Sbjct: 154 QADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTM---SPEVH 210
Query: 206 ATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLI 265
+N C++ + Y N+FWM EG YLHT IV+ ++ + +GWG P
Sbjct: 211 QSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFP 270
Query: 266 PACIHAIARSLYYNDNCWISS--DTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVT 323
AI + Y N+ CW + YI GP+ LL+N FL NIVR+L+TKL+ +
Sbjct: 271 IIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRAS 330
Query: 324 HQAESNLYMKAVRATLILVPLLGIEFVLIPWRP-EGKIAEEVYDYIMHILMHFQGLLVST 382
+E+ Y KAV+ATL+L+PLLGI ++L P E +++ V+ Y L FQG VS
Sbjct: 331 TTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSV 390
Query: 383 IFCFFNGEVQAILRRNWNQYK 403
+CF N EV++ +R+ W++++
Sbjct: 391 FYCFLNSEVRSAIRKRWHRWQ 411
>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
[Homo sapiens]
Length = 401
Score = 161 bits (408), Expect = 1e-39
Identities = 104/352 (29%), Positives = 176/352 (50%), Gaps = 34/352 (9%)
Query: 62 GVYCNRTWDG-WLCWNDVAAGTESMQLCPDYFQD--FDPSEKVTKICDQDGNWFRHPASN 118
G+ CN + D CW AG ++ CP +F ++ + + C +G+W
Sbjct: 41 GLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAAR---- 96
Query: 119 RTWTNYTQCNVNTHEKVKTALNLFYLTII---GHGLSIASLLISLGIFFYFKSLSCQRIT 175
NY++C +E+ K+ ++ II GH +S+ +LL++ +F +S+ C R
Sbjct: 97 ---VNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNI 153
Query: 176 LHKNLFFSFVC-NSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEG 234
+H NL +F+ N+ ++ LT + + +N C++ + Y N+FWM EG
Sbjct: 154 IHWNLISAFILRNATWFVVQLTM---SPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEG 210
Query: 235 IYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISS--DTHLLY 292
YLHT IV+ ++ + +GWG P AI + Y N+ CW + Y
Sbjct: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270
Query: 293 IIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLI 352
I GP+ LL+N FL NIVR+L+TKL+ + +E+ Y KAV+ATL+L+PLLGI ++L
Sbjct: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLF 330
Query: 353 PWRP-EGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYK 403
P E +++ V+ Y L FQ V++ +R+ W++++
Sbjct: 331 FVNPGEDEVSRVVFIYFNSFLESFQ--------------VRSAIRKRWHRWQ 368
>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
Length = 438
Score = 155 bits (392), Expect = 7e-38
Identities = 99/350 (28%), Positives = 174/350 (49%), Gaps = 26/350 (7%)
Query: 65 CNRTWDGWLCWNDVAAGTESMQLCPDYFQDF-DPSEKVTKICDQDGNWFRHPASNRTWTN 123
C+ WD CW G CP F +F + ++K C DG W + T+ +
Sbjct: 52 CSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDG-W------SETFPD 104
Query: 124 YTQCNVNTHEKVKTALNLFYLT----IIGHGLSIASLLISLGIFFYFKSLSCQRITLHKN 179
+ + + ++ + + L +G+ +S+ SL I F+ L C R +H N
Sbjct: 105 FVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLN 164
Query: 180 LFFSFVCNSVVTIIHLTAVANNQALV-----ATNPVSCKVSQFIHLYLMGCNYFWMLCEG 234
LF SF+ ++ ++ + ++ + ++ V CK+S Y + N+FW+L EG
Sbjct: 165 LFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEG 224
Query: 235 IYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHA-IARSLYYND-NCWISSDTHL-L 291
+YLHTL+ VA+ ++ + Y +GWG P + CI A A LY D CW ++D +
Sbjct: 225 LYLHTLL-VAMLPPRRCFLAYLLIGWGLPTV--CIGAWTAARLYLEDTGCWDTNDHSVPW 281
Query: 292 YIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQA--ESNLYMKAVRATLILVPLLGIEF 349
++I PI +++VN ++I+R+L+ KL + + Y + ++TL+L+PL G+ +
Sbjct: 282 WVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHY 341
Query: 350 VLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNW 399
++ P I+ + L FQGL+V+ ++CF N EVQ L+R W
Sbjct: 342 MVFAVFPI-SISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390
>gi|58530851 growth hormone releasing hormone receptor isoform a
precursor [Homo sapiens]
Length = 423
Score = 137 bits (346), Expect = 2e-32
Identities = 92/347 (26%), Positives = 158/347 (45%), Gaps = 20/347 (5%)
Query: 65 CNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDP-SEKVTKICDQDGNWFRHPASNRTWTN 123
C TWDG LCW +G CPD+F F S V + C G W
Sbjct: 55 CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-WSEPFPPYPVACP 113
Query: 124 YTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFS 183
+ E + + + Y +GH +SI +L +++ I + L C R +H LF +
Sbjct: 114 VPLELLAEEESYFSTVKIIYT--VGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTT 171
Query: 184 FVCNSVVTIIHLTAVANNQAL--VATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLI 241
F+ + + A+ ++ + + V CKVS + N+ W+L E +YL+ L+
Sbjct: 172 FILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLL 231
Query: 242 VVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTH-LLYIIHGPICA 300
+ ++ W GWG P++ + + + CW DT +II GPI
Sbjct: 232 ASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVL 291
Query: 301 ALLVNLFFLLNIVRVLITKLKVTHQA--ESNLYMKAVRATLILVPLLGIEFVLIPWRPEG 358
++ VN LNI+R+L+ KL+ + + Y + ++TL L+PL GI +++ + P+
Sbjct: 292 SVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDN 351
Query: 359 -----KIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWN 400
++ E+ L FQG +V+ ++CF N EV+ + R W+
Sbjct: 352 AGLGIRLPLELG------LGSFQGFIVAILYCFLNQEVRTEISRKWH 392
>gi|58530853 growth hormone releasing hormone receptor isoform b
precursor [Homo sapiens]
Length = 337
Score = 105 bits (263), Expect = 7e-23
Identities = 70/261 (26%), Positives = 115/261 (44%), Gaps = 7/261 (2%)
Query: 65 CNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDP-SEKVTKICDQDGNWFRHPASNRTWTN 123
C TWDG LCW +G CPD+F F S V + C G W
Sbjct: 55 CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-WSEPFPPYPVACP 113
Query: 124 YTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFS 183
+ E + + + Y +GH +SI +L +++ I + L C R +H LF +
Sbjct: 114 VPLELLAEEESYFSTVKIIYT--VGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTT 171
Query: 184 FVCNSVVTIIHLTAVANNQAL--VATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLI 241
F+ + + A+ ++ + + V CKVS + N+ W+L E +YL+ L+
Sbjct: 172 FILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLL 231
Query: 242 VVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTH-LLYIIHGPICA 300
+ ++ W GWG P++ + + + CW DT +II GPI
Sbjct: 232 ASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVL 291
Query: 301 ALLVNLFFLLNIVRVLITKLK 321
++ VN LNI+R+L+ KL+
Sbjct: 292 SVGVNFGLFLNIIRILVRKLE 312
>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
Length = 874
Score = 97.1 bits (240), Expect = 3e-20
Identities = 68/261 (26%), Positives = 123/261 (47%), Gaps = 19/261 (7%)
Query: 144 LTIIGHGLSIASLLISLGIFFYFKSLSC---QRITLHKNLFFSFVCNSVVTIIHLTAVAN 200
++ +G LS+ L+ +L F S+S QR +H NL F+ + V+ +I
Sbjct: 569 ISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPG 628
Query: 201 NQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGW 260
T P C+V + Y + WML EG++L+++++ +E +YY +GW
Sbjct: 629 ------TTP--CQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGW 680
Query: 261 GFPLIPACIHAIA---RSLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVL- 316
GFPL+ CI +++ S ++NCW+S + ++ P ++VN+ L+ + RV+
Sbjct: 681 GFPLL-ICIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRVIS 739
Query: 317 -ITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHILMHF 375
I+ + + + +A +L+P+LG +V G V+ Y+ L
Sbjct: 740 QISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNG--CAVVFQYMFATLNSL 797
Query: 376 QGLLVSTIFCFFNGEVQAILR 396
QGL + C N EV+A +
Sbjct: 798 QGLFIFLFHCLLNSEVRAAFK 818
>gi|163792198 latrophilin 3 precursor [Homo sapiens]
Length = 1469
Score = 80.9 bits (198), Expect = 2e-15
Identities = 51/181 (28%), Positives = 87/181 (48%), Gaps = 12/181 (6%)
Query: 132 HEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVT 191
H L L +T +G LS+ LLI + F +F+ L R T+HKNL S ++
Sbjct: 868 HSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLF 927
Query: 192 IIHLTAVANNQALVATNPVSCKV-SQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQ 250
+I + P++C V + +H + + + WM EG+ L+ ++V +E
Sbjct: 928 LIGINRT--------DQPIACAVFAALLHFFFLAA-FTWMFLEGVQLYIMLVEVFESEHS 978
Query: 251 HLMWYYFLGWGFP-LIPACIHAIARSLYYNDN-CWISSDTHLLYIIHGPICAALLVNLFF 308
++Y +G+G P LI A A+ Y D CW+ DT+ ++ GP +++N+ F
Sbjct: 979 RRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIF 1038
Query: 309 L 309
L
Sbjct: 1039 L 1039
>gi|148806925 EGF, latrophilin and seven transmembrane domain
containing 1 [Homo sapiens]
Length = 690
Score = 79.3 bits (194), Expect = 7e-15
Identities = 82/311 (26%), Positives = 130/311 (41%), Gaps = 37/311 (11%)
Query: 117 SNRTWTNYTQCNVNTHEKVKTALN----------LFYLTIIGHGLSIASLLISLGIFFYF 166
SN T T+ +CN TH + + L +T +G +S+ L I + F++F
Sbjct: 394 SNETHTS-CRCNHLTHFAILMSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFF 452
Query: 167 KSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCN 226
+ R T+HKNL S + ++ L + N TN + C + + Y
Sbjct: 453 SEIQSTRTTIHKNLCCSLF---LAELVFLVGINTN-----TNKLFCSIIAGLLHYFFLAA 504
Query: 227 YFWMLCEGIYLHTLIVVAVFAEKQHL-MWYYFLGWGFPLIPACIHAIARSLYYNDN--CW 283
+ WM EGI+L+ LIVV V K L +Y G+ P + A YY CW
Sbjct: 505 FAWMCIEGIHLY-LIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCW 563
Query: 284 ISSDTHLLYIIHGPICAALLVNLF-FLLNIVRVL--ITKLKVTHQAESNLYMKAVRATLI 340
+S++ + ++ GP C +LVNL F + I +V LK N+ R L
Sbjct: 564 LSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENI-RSCARGALA 622
Query: 341 LVPLLGIEFVLIPWRPEGKI----AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILR 396
L+ LLG ++ G + A V Y+ + FQG+ + C + ++Q
Sbjct: 623 LLFLLGTTWIF------GVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYY 676
Query: 397 RNWNQYKIQFG 407
R + FG
Sbjct: 677 RLFKNVPCCFG 687
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 78.2 bits (191), Expect = 1e-14
Identities = 76/302 (25%), Positives = 130/302 (43%), Gaps = 29/302 (9%)
Query: 139 LNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAV 198
L L +T LS+A+LL++ + + L ++HK+L + + +V +I +
Sbjct: 2466 LPLKIVTYAAVSLSLAALLVAFVLLSLVRMLRSNLHSIHKHLAVALFLSQLVFVIGI--- 2522
Query: 199 ANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFL 258
NQ NP C V + Y+ + W L E ++++ ++ + + +YY +
Sbjct: 2523 --NQT---ENPFLCTVVAILLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMRFYYVV 2577
Query: 259 GWGFPLIPACIHAIARSL----YYN-DNCWISSDTHLLYIIHGPICAALLVNLFFLLNIV 313
GWG IPA + +A L Y N D CW+S L++ GPI A +++N +
Sbjct: 2578 GWG---IPAIVTGLAVGLDPQGYGNPDFCWLSLQDTLIWSFAGPIGAVIIIN-----TVT 2629
Query: 314 RVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKIAEE----VYDYIM 369
VL KV+ Q + + Y K +L+ L + + W G +A + Y+
Sbjct: 2630 SVL--SAKVSCQRKHHYYGKKGIVSLLRTAFLLLLLISATWL-LGLLAVNRDALSFHYLF 2686
Query: 370 HILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSASYTV-STISD 428
I QG V C N EV+ L+ K+ +S + L + S +T D
Sbjct: 2687 AIFSGLQGPFVLLFHCVLNQEVRKHLKGVLGGRKLHLEDSATTRATLLTRSLNCNTTFGD 2746
Query: 429 GP 430
GP
Sbjct: 2747 GP 2748
>gi|40807489 egf-like module containing, mucin-like, hormone
receptor-like sequence 1 [Homo sapiens]
Length = 886
Score = 77.0 bits (188), Expect = 3e-14
Identities = 73/320 (22%), Positives = 140/320 (43%), Gaps = 31/320 (9%)
Query: 124 YTQCNVNTHEKVKTAL---------NLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRI 174
YT C+ N + + +L+ ++ +G +S+ L++++ F +S+
Sbjct: 576 YTICSCNQMANLAVIMASGELTMDFSLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNT 635
Query: 175 TLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKV-SQFIHLYLMGCNYFWMLCE 233
LH +L VC + + L + N + C + + F+H + C +FWML E
Sbjct: 636 YLHLHLC---VCLLLAKTLFLAGIHKTD-----NKMGCAIIAGFLHYLFLAC-FFWMLVE 686
Query: 234 GIYLHTLI----VVAVFAEKQHLMWYYF-LGWGFPLIPACIHAIARSLYY--NDNCWISS 286
+ L ++ VV F+ + M + G+G P++ I A + Y ++ CW+++
Sbjct: 687 AVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNT 746
Query: 287 DTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPL-- 344
+T ++ GP+C +++N L + +L +L + S L + L
Sbjct: 747 ETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFI 806
Query: 345 LGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKI 404
LG +VL ++ G +A V Y+ I+ QG + I C NG+V+ +R W K
Sbjct: 807 LGCSWVLGIFQ-IGPVA-GVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKR-WITGKT 863
Query: 405 QFGNSFSNSEALRSASYTVS 424
+ + S L S+ + S
Sbjct: 864 KPSSQSQTSRILLSSMPSAS 883
>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
Length = 1474
Score = 75.5 bits (184), Expect = 1e-13
Identities = 64/259 (24%), Positives = 108/259 (41%), Gaps = 18/259 (6%)
Query: 139 LNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAV 198
L L +T +G +S+ L I + F + + L R T+HKNL + + ++ L +
Sbjct: 858 LLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLF---LAELLFLVGI 914
Query: 199 ANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFL 258
Q +A C + + Y + W+ EG++L+ L+V +E +YY
Sbjct: 915 DKTQYEIA-----CPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLG 969
Query: 259 GWGFPLIPACIHAIA--RSLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVL 316
G+ FP + I A RS CW+ D + ++ GP+ ++VNL FL+ + +
Sbjct: 970 GYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKM 1029
Query: 317 ITKLKVTHQAESNL--YMKAVRATLILVPLLGI--EFVLIPWRPEGKIAEEVYDYIMHIL 372
I V S L + L+ LLG+ F L+ E V Y+
Sbjct: 1030 IRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKE----SVVMAYLFTTF 1085
Query: 373 MHFQGLLVSTIFCFFNGEV 391
FQG+ + C +V
Sbjct: 1086 NAFQGVFIFVFHCALQKKV 1104
>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
Length = 1469
Score = 75.5 bits (184), Expect = 1e-13
Identities = 64/259 (24%), Positives = 108/259 (41%), Gaps = 18/259 (6%)
Query: 139 LNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAV 198
L L +T +G +S+ L I + F + + L R T+HKNL + + ++ L +
Sbjct: 853 LLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLF---LAELLFLVGI 909
Query: 199 ANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFL 258
Q +A C + + Y + W+ EG++L+ L+V +E +YY
Sbjct: 910 DKTQYEIA-----CPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLG 964
Query: 259 GWGFPLIPACIHAIA--RSLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVL 316
G+ FP + I A RS CW+ D + ++ GP+ ++VNL FL+ + +
Sbjct: 965 GYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKM 1024
Query: 317 ITKLKVTHQAESNL--YMKAVRATLILVPLLGI--EFVLIPWRPEGKIAEEVYDYIMHIL 372
I V S L + L+ LLG+ F L+ E V Y+
Sbjct: 1025 IRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKE----SVVMAYLFTTF 1080
Query: 373 MHFQGLLVSTIFCFFNGEV 391
FQG+ + C +V
Sbjct: 1081 NAFQGVFIFVFHCALQKKV 1099
>gi|240120161 G protein-coupled receptor 144 [Homo sapiens]
Length = 963
Score = 74.7 bits (182), Expect = 2e-13
Identities = 63/270 (23%), Positives = 115/270 (42%), Gaps = 32/270 (11%)
Query: 144 LTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQA 203
L+ +G G+S +L + +F +R T+HKNL FS + A AN A
Sbjct: 661 LSFVGCGVSFCALTTTFLLFLVAGVPKSERTTVHKNLTFSLASAEGFLMTSEWAKANEVA 720
Query: 204 LVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFP 263
VA V+ +H +L + WML EG+ L +V + Y+ GWG P
Sbjct: 721 CVA-------VTVAMH-FLFLVAFSWMLVEGLLLWRKVVAVSMHPGPGMRLYHATGWGVP 772
Query: 264 --LIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLK 321
++ + + +CW++ T+ ++ GP+ L N L +V + ++ +
Sbjct: 773 VGIVAVTLAMLPHDYVAPGHCWLNVHTNAIWAFVGPVLFVLTANTCILARVVMITVSSAR 832
Query: 322 -----------VTHQAESNLYMKAVRATLILVPLLGIEF---VLIPWRPEGKIAEEVYDY 367
+ Q + ++ V+ L+L+P+LG+ + +L+ P + Y
Sbjct: 833 RRARMLSPQPCLQQQIWTQIW-ATVKPVLVLLPVLGLTWLAGILVHLSP-------AWAY 884
Query: 368 IMHILMHFQGLLVSTIFCFFNGEVQAILRR 397
L QGL + ++ N EV++ L+R
Sbjct: 885 AAVGLNSIQGLYIFLVYAACNEEVRSALQR 914
>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
sapiens]
Length = 652
Score = 73.9 bits (180), Expect = 3e-13
Identities = 74/297 (24%), Positives = 128/297 (43%), Gaps = 34/297 (11%)
Query: 141 LFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVAN 200
L +T +G +S+ LL++ F K++ +LH L +C + ++ L +
Sbjct: 356 LTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLS---LCLFLAHLLFLVGIDR 412
Query: 201 NQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYL----HTLIVVAVFAEKQHLMWYY 256
+ V C + YL + WML EG++L L VV + + + W
Sbjct: 413 TEPKVL-----CSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIM 467
Query: 257 F-LGWGFPLIPACIHAIARSLYYN--DNCWISSDTHLLYIIHGPICAALLVNLFFLLNIV 313
F +G+G P + I A + Y D CW+ D ++ GP+CA NL + +
Sbjct: 468 FPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVF 527
Query: 314 RVLITKLKVTHQAES---NLYMKAVRATLILVPLLGIEFV--LIPWRPEGKIAEEVYDYI 368
+L KL + S N M A +AT L +LG + L+ P A +V Y+
Sbjct: 528 WILKRKLSSLNSEVSTIQNTRMLAFKATAQLF-ILGCTWCLGLLQVGP----AAQVMAYL 582
Query: 369 MHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSASYTVST 425
I+ QG + ++C + +VQ + + ++ + S S SE +YT+S+
Sbjct: 583 FTIINSLQGFFIFLVYCLLSQQVQ----KQYQKWFREIVKSKSESE-----TYTLSS 630
>gi|6912464 latrophilin 2 precursor [Homo sapiens]
Length = 1403
Score = 72.0 bits (175), Expect = 1e-12
Identities = 64/266 (24%), Positives = 115/266 (43%), Gaps = 30/266 (11%)
Query: 139 LNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAV 198
L L +T +G +S+ L I + F +F+ L R T+HKNL + + I L +
Sbjct: 832 LLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLF---IAEFIFLIGI 888
Query: 199 ANNQALVATNPVSCKV-SQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYF 257
+ +A C + + +H + + + WM EG+ L+ ++V +E +YY
Sbjct: 889 DKTKYAIA-----CPIFAGLLHFFFLAA-FAWMCLEGVQLYLMLVEVFESEYSRKKYYYV 942
Query: 258 LGWGFPLIPACIHAIARSLYYND-----NCWISSDTHLLYIIHGPICAALLVNLFFLLNI 312
G+ L PA + ++ ++ Y CW+ D + ++ GP+ +L+N+ FL+
Sbjct: 943 AGY---LFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNIIFLVIT 999
Query: 313 VRVLITKLKVTHQAESNL--YMKAVRATLILVPLLGI--EFVLIPWRPEGKIAEE--VYD 366
+ ++ S L V L+ LLG+ F L+ I EE V
Sbjct: 1000 LCKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLL------FINEETIVMA 1053
Query: 367 YIMHILMHFQGLLVSTIFCFFNGEVQ 392
Y+ I FQG+ + C +V+
Sbjct: 1054 YLFTIFNAFQGVFIFIFHCALQKKVR 1079
>gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapiens]
Length = 1079
Score = 66.2 bits (160), Expect = 6e-11
Identities = 70/277 (25%), Positives = 119/277 (42%), Gaps = 29/277 (10%)
Query: 141 LFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFF--SFVCNSVVTIIHLTAV 198
L LT +G G SI +LL+ LG+++ L + + +K +F + + N V ++
Sbjct: 770 LALLTQVGLGASILALLVCLGVYW----LVWRVVVRNKISYFRHAALLNMVFCLLAADTC 825
Query: 199 ANNQALVATNPVS--CKVSQFIHLYLMGCNYFWMLCEGIYL--HTLIVVAVFAEKQHLMW 254
++ P S C + F+ +L +FWML + + L L V A+ + L
Sbjct: 826 FLGAPFLSPGPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPL 885
Query: 255 YYFLGWGFPLIPACIHAIARSLYY-------NDNCWISSDTHLLYIIHGPICAALLVN-L 306
LG+ L P + + LY CW+ LY GP+ A + VN L
Sbjct: 886 MVLLGY---LCPLGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGVNGL 942
Query: 307 FFLLNIVRVLITKLKVTHQAES-NLYMKAVRATLILVPLLGIEFVLIPWRPEGKIAEEVY 365
+ ++++L L AE + ++A LIL P+ G+ + L + EEV
Sbjct: 943 VLAMAMLKLLRPSLSEGPPAEKRQALLGVIKALLILTPIFGLTWGL----GLATLLEEVS 998
Query: 366 ---DYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNW 399
YI IL QG+ + C + ++Q LR+ +
Sbjct: 999 TVPHYIFTILNTLQGVFILLFGCLMDRKIQEALRKRF 1035
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.139 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,164,662
Number of Sequences: 37866
Number of extensions: 717473
Number of successful extensions: 2140
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 1943
Number of HSP's gapped (non-prelim): 99
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.