BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5031581 adaptor-related protein complex 3, sigma 2 subunit [Homo sapiens] (193 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5031581 adaptor-related protein complex 3, sigma 2 subunit [H... 385 e-108 gi|4502861 adaptor-related protein complex 3, sigma 1 subunit [H... 333 5e-92 gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [H... 111 3e-25 gi|70906430 adaptor-related protein complex 2, sigma 1 subunit i... 110 7e-25 gi|88703051 adaptor-related protein complex 1, sigma 3 subunit [... 110 1e-24 gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [H... 109 2e-24 gi|189409104 adaptor-related protein complex 4, sigma 1 subunit ... 104 4e-23 gi|21361394 adaptor-related protein complex 4, sigma 1 subunit i... 72 2e-13 gi|11038643 adaptor-related protein complex 2, sigma 1 subunit i... 61 5e-10 gi|7705983 coatomer protein complex, subunit zeta 2 [Homo sapiens] 52 2e-07 gi|7706337 coatomer protein complex, subunit zeta 1 [Homo sapiens] 49 2e-06 gi|31542246 kelch-like 36 [Homo sapiens] 31 0.57 gi|55741632 fibronectin type III and SPRY domain containing 2 [H... 30 1.3 gi|4557485 ceruloplasmin precursor [Homo sapiens] 28 3.7 gi|7019591 zinc finger protein 224 [Homo sapiens] 28 6.3 gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens] 27 8.3 gi|22748675 RAB42, member RAS oncogene family [Homo sapiens] 27 8.3 gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 27 8.3 gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 27 8.3 >gi|5031581 adaptor-related protein complex 3, sigma 2 subunit [Homo sapiens] Length = 193 Score = 385 bits (990), Expect = e-108 Identities = 193/193 (100%), Positives = 193/193 (100%) Query: 1 MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSD 60 MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSD Sbjct: 1 MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSD 60 Query: 61 YKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYIL 120 YKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYIL Sbjct: 61 YKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYIL 120 Query: 121 QEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEIPRNINIG 180 QEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEIPRNINIG Sbjct: 121 QEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEIPRNINIG 180 Query: 181 DLNIKVPNLSQFV 193 DLNIKVPNLSQFV Sbjct: 181 DLNIKVPNLSQFV 193 >gi|4502861 adaptor-related protein complex 3, sigma 1 subunit [Homo sapiens] Length = 193 Score = 333 bits (854), Expect = 5e-92 Identities = 162/192 (84%), Positives = 178/192 (92%) Query: 1 MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSD 60 MI+AIL+FNNHGKPRL +FYQ + E+ QQQI+RETFHLV KRD+N+CNFLEGG LIGGSD Sbjct: 1 MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSD 60 Query: 61 YKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYIL 120 KLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFH+DKVH IL Sbjct: 61 NKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNIL 120 Query: 121 QEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEIPRNINIG 180 E+VMGGMVLETNMNEIV QI+AQN+LEKSE GL+ APARAVSAVKN+NLPEIPRNINIG Sbjct: 121 AEMVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIG 180 Query: 181 DLNIKVPNLSQF 192 D++IKVPNL F Sbjct: 181 DISIKVPNLPSF 192 >gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [Homo sapiens] Length = 158 Score = 111 bits (278), Expect = 3e-25 Identities = 56/151 (37%), Positives = 97/151 (64%), Gaps = 6/151 (3%) Query: 1 MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSD 60 M++ +L+F+ GK RL ++Y ++ ++++VRE +VL R +C+FLE D Sbjct: 1 MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEW------RD 54 Query: 61 YKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYIL 120 K++Y+ YA+LYF ++ ++EL L+LI +VE LDK F +VCELD+IF+ +K ++IL Sbjct: 55 LKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFIL 114 Query: 121 QEVVMGGMVLETNMNEIVAQIEAQNRLEKSE 151 E +MGG V +T+ ++ IE + L++ + Sbjct: 115 DEFLMGGDVQDTSKKSVLKAIEQADLLQEED 145 >gi|70906430 adaptor-related protein complex 2, sigma 1 subunit isoform AP17 [Homo sapiens] Length = 142 Score = 110 bits (275), Expect = 7e-25 Identities = 56/148 (37%), Positives = 91/148 (61%), Gaps = 6/148 (4%) Query: 1 MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSD 60 MI+ IL+ N GK RL ++Y +F ++ +Q+++ E +V RD NF+E + Sbjct: 1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEF------RN 54 Query: 61 YKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYIL 120 +K+IYR YA LYF CVD +++ L L+ I FVE L++ F NVCELDL+F+ KV+ ++ Sbjct: 55 FKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVV 114 Query: 121 QEVVMGGMVLETNMNEIVAQIEAQNRLE 148 E+ + G + ET+ +++ Q+ LE Sbjct: 115 DEMFLAGEIRETSQTKVLKQLLMLQSLE 142 >gi|88703051 adaptor-related protein complex 1, sigma 3 subunit [Homo sapiens] Length = 154 Score = 110 bits (274), Expect = 1e-24 Identities = 55/150 (36%), Positives = 94/150 (62%), Gaps = 6/150 (4%) Query: 1 MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSD 60 MI IL+F+ GK RL ++Y P++ +++I RE ++L R +F++ L Sbjct: 1 MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKEL----- 55 Query: 61 YKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYIL 120 KL+Y+ YA+LYF +++ ++EL L+++ +VE LDK F NVCELD+IF+ +K ++IL Sbjct: 56 -KLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFIL 114 Query: 121 QEVVMGGMVLETNMNEIVAQIEAQNRLEKS 150 E ++GG + ET+ V IE + L+++ Sbjct: 115 DEFIIGGEIQETSKKIAVKAIEDSDMLQET 144 >gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [Homo sapiens] Length = 157 Score = 109 bits (272), Expect = 2e-24 Identities = 55/148 (37%), Positives = 93/148 (62%), Gaps = 6/148 (4%) Query: 2 IQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDY 61 +Q +L+F+ GK RL ++Y ++ +++I RE VL R +C+FLE D Sbjct: 1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEW------RDL 54 Query: 62 KLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQ 121 K++Y+ YA+LYF ++ ++EL L++I +VE LDK F +VCELD+IF+ +K ++IL Sbjct: 55 KIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILD 114 Query: 122 EVVMGGMVLETNMNEIVAQIEAQNRLEK 149 E ++GG V ET+ ++ IE + L++ Sbjct: 115 EFLLGGEVQETSKKNVLKAIEQADLLQE 142 >gi|189409104 adaptor-related protein complex 4, sigma 1 subunit isoform 2 [Homo sapiens] Length = 144 Score = 104 bits (260), Expect = 4e-23 Identities = 55/150 (36%), Positives = 88/150 (58%), Gaps = 6/150 (4%) Query: 1 MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSD 60 MI+ L+ N G+ RL ++Y+ + + E L R + C+F+E D Sbjct: 1 MIKFFLMVNKQGQTRLSKYYEHVDINKRTLLETEVIKSCLSRSNEQCSFIEY------KD 54 Query: 61 YKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYIL 120 +KLIYR YA L+ V V+ +E+E+ I + I FVE LD+ F V ELD++F++DKVH IL Sbjct: 55 FKLIYRQYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDIMFNLDKVHIIL 114 Query: 121 QEVVMGGMVLETNMNEIVAQIEAQNRLEKS 150 E+V+ G ++ETN I+A + +++ +S Sbjct: 115 DEMVLNGCIVETNRARILAPLLILDKMSES 144 >gi|21361394 adaptor-related protein complex 4, sigma 1 subunit isoform 1 [Homo sapiens] Length = 159 Score = 72.4 bits (176), Expect = 2e-13 Identities = 41/117 (35%), Positives = 61/117 (52%), Gaps = 6/117 (5%) Query: 1 MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSD 60 MI+ L+ N G+ RL ++Y+ + + E L R + C+F+E D Sbjct: 1 MIKFFLMVNKQGQTRLSKYYEHVDINKRTLLETEVIKSCLSRSNEQCSFIEY------KD 54 Query: 61 YKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVH 117 +KLIYR YA L+ V V+ +E+E+ I + I FVE LD+ F V ELD+ F H Sbjct: 55 FKLIYRQYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDVSFFNTVFH 111 >gi|11038643 adaptor-related protein complex 2, sigma 1 subunit isoform AP17delta [Homo sapiens] Length = 104 Score = 61.2 bits (147), Expect = 5e-10 Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 44/148 (29%) Query: 1 MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSD 60 MI+ IL+ N GK RL ++Y +F ++ +Q+++ E +V RD NF Sbjct: 1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNF----------- 49 Query: 61 YKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYIL 120 VE L++ F NVCELDL+F+ KV+ ++ Sbjct: 50 ---------------------------------VEVLNEYFHNVCELDLVFNFYKVYTVV 76 Query: 121 QEVVMGGMVLETNMNEIVAQIEAQNRLE 148 E+ + G + ET+ +++ Q+ LE Sbjct: 77 DEMFLAGEIRETSQTKVLKQLLMLQSLE 104 >gi|7705983 coatomer protein complex, subunit zeta 2 [Homo sapiens] Length = 210 Score = 52.4 bits (124), Expect = 2e-07 Identities = 38/157 (24%), Positives = 80/157 (50%), Gaps = 16/157 (10%) Query: 2 IQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRE--TFHLVLKRDDNICNFLEGGSLIGGS 59 I+A+ + +N G+ L ++Y +++Q+V E F+ + + I F GG I Sbjct: 46 IKAVFILDNDGRRLLAKYYDDTFPSMKEQMVFEKNVFNKTSRTESEIAFF--GGMTI--- 100 Query: 60 DYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCF-ENVCELDLIFHMDKVHY 118 +Y++ L+ S E+EL ++ ++ E+L+ +NV + L+ +MD Sbjct: 101 ----VYKNSIDLFLYVVGSSYENELMLMSVLTCLFESLNHMLRKNVEKRWLLENMDGAFL 156 Query: 119 ILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLS 155 +L E+V GG++LE++ +++ ++ +GGL+ Sbjct: 157 VLDEIVDGGVILESDPQQVIQKV----NFRADDGGLT 189 >gi|7706337 coatomer protein complex, subunit zeta 1 [Homo sapiens] Length = 177 Score = 49.3 bits (116), Expect = 2e-06 Identities = 33/142 (23%), Positives = 71/142 (50%), Gaps = 10/142 (7%) Query: 2 IQAILVFNNHGKPRLVRFYQ-RFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSD 60 ++AIL+ +N G ++Y +P +Q+ + R D+ LEG Sbjct: 13 VKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEG-------- 64 Query: 61 YKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCF-ENVCELDLIFHMDKVHYI 119 ++Y+ LYF S E+EL ++ ++ ++L + +NV + L+ +M+ + Sbjct: 65 LTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLA 124 Query: 120 LQEVVMGGMVLETNMNEIVAQI 141 + E+V GG++LE++ ++V ++ Sbjct: 125 VDEIVDGGVILESDPQQVVHRV 146 >gi|31542246 kelch-like 36 [Homo sapiens] Length = 616 Score = 31.2 bits (69), Expect = 0.57 Identities = 36/149 (24%), Positives = 68/149 (45%), Gaps = 23/149 (15%) Query: 46 ICNFLEGGSLI---GGSDYKLIYRHYATLYFV--FCVDSSESELG------ILDLIQVF- 93 + +FL GG L+ G DY L H ++ V FC + E E+ + +L ++ Sbjct: 100 VVDFLYGGELVLDGGNIDYVLETAHLLQIWTVVDFCCEYLEQEVSEDNYLYLQELASIYS 159 Query: 94 VETLDKCFENVCELDLIFHMDKVHY---ILQEVVMGGMVLETNMNEIVAQIEAQNRLEKS 150 ++ LD + ++ H + + LQ V M + + + +E+ + E + L+ + Sbjct: 160 LKRLDAFIDGF----ILNHFGTLSFTPDFLQNVSMQKLCVYLSSSEVQRECE-HDLLQAA 214 Query: 151 EGGLSAAPARAVSA---VKNINLPEIPRN 176 L+ P R A ++NI+ P IP+N Sbjct: 215 LQWLTQQPEREAHARQVLENIHFPLIPKN 243 >gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo sapiens] Length = 749 Score = 30.0 bits (66), Expect = 1.3 Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 14/92 (15%) Query: 95 ETLDKCFENVCELDLIFHMDKVHYILQEVVMG---GMVLETNMN-EIVAQIEAQNR---- 146 E LD C E + ++ + H +KV +I V M G L+T + EI AQ E +++ Sbjct: 297 ENLDTCKELMETIEEMCHEEKVDFIKDAVAMADRLGKFLKTKTDVEISAQPEFEDQTLDF 356 Query: 147 --LEKSEGGLSAAPARAVSAVKNINLPEIPRN 176 +E+ G ++ PA + + P++P + Sbjct: 357 SDVEQLMGSINTIPAPSAPVIN----PQVPNS 384 >gi|4557485 ceruloplasmin precursor [Homo sapiens] Length = 1065 Score = 28.5 bits (62), Expect = 3.7 Identities = 19/53 (35%), Positives = 25/53 (47%), Gaps = 2/53 (3%) Query: 37 HLVLKRDDNICNFLEGGSLIGGSDYKLIYRHYATLYFVFCVD--SSESELGIL 87 +L D+ F +G + IGGS KL+YR Y F + E LGIL Sbjct: 397 NLTAPGSDSAVFFEQGTTRIGGSYKKLVYREYTDASFTNRKERGPEEEHLGIL 449 >gi|7019591 zinc finger protein 224 [Homo sapiens] Length = 707 Score = 27.7 bits (60), Expect = 6.3 Identities = 15/48 (31%), Positives = 28/48 (58%), Gaps = 3/48 (6%) Query: 80 SESELGILDLIQ--VFVETLDKCFENVCEL-DLIFHMDKVHYILQEVV 124 +E ELG+LDL Q ++ + + + F N+ + FH D H++ +E + Sbjct: 18 TEEELGLLDLAQRKLYRDVMLENFRNLLSVGHQAFHRDTFHFLREEKI 65 >gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens] Length = 515 Score = 27.3 bits (59), Expect = 8.3 Identities = 16/60 (26%), Positives = 33/60 (55%), Gaps = 8/60 (13%) Query: 8 FNNHGKPRLVRFYQRFPEEIQQQIVRETFH----LVLKRDDNIC--NFLEGGSLIGGSDY 61 F+ H P+ + + P+E +++ + +++ R +N C NFL+ GS+I G+D+ Sbjct: 255 FSKH--PQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRGSIINGADW 312 >gi|22748675 RAB42, member RAS oncogene family [Homo sapiens] Length = 105 Score = 27.3 bits (59), Expect = 8.3 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 5/62 (8%) Query: 63 LIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFH--MDKVHYIL 120 L+ H + L CV + E+E L FVET K N C +DL F D + L Sbjct: 12 LLVGHKSDLQSTRCVSAQEAEELAASLGMAFVETSVK---NNCNVDLAFDTLADAIQQAL 68 Query: 121 QE 122 Q+ Sbjct: 69 QQ 70 >gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] Length = 641 Score = 27.3 bits (59), Expect = 8.3 Identities = 16/60 (26%), Positives = 33/60 (55%), Gaps = 8/60 (13%) Query: 8 FNNHGKPRLVRFYQRFPEEIQQQIVRETFH----LVLKRDDNIC--NFLEGGSLIGGSDY 61 F+ H P+ + + P+E +++ + +++ R +N C NFL+ GS+I G+D+ Sbjct: 381 FSKH--PQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRGSIINGADW 438 >gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] Length = 652 Score = 27.3 bits (59), Expect = 8.3 Identities = 16/60 (26%), Positives = 33/60 (55%), Gaps = 8/60 (13%) Query: 8 FNNHGKPRLVRFYQRFPEEIQQQIVRETFH----LVLKRDDNIC--NFLEGGSLIGGSDY 61 F+ H P+ + + P+E +++ + +++ R +N C NFL+ GS+I G+D+ Sbjct: 392 FSKH--PQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRGSIINGADW 449 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.141 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,512,719 Number of Sequences: 37866 Number of extensions: 253365 Number of successful extensions: 677 Number of sequences better than 10.0: 19 Number of HSP's better than 10.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 657 Number of HSP's gapped (non-prelim): 19 length of query: 193 length of database: 18,247,518 effective HSP length: 97 effective length of query: 96 effective length of database: 14,574,516 effective search space: 1399153536 effective search space used: 1399153536 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.