Guide to the Human Genome
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Search of human proteins with 4826950

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4826950 stratum corneum chymotryptic enzyme preproprotein
[Homo sapiens]
         (253 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H...   530   e-151
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho...   530   e-151
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ...   237   8e-63
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ...   237   8e-63
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa...   237   8e-63
gi|91823048 kallikrein 14 preproprotein [Homo sapiens]                226   2e-59
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]        224   4e-59
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]                     224   7e-59
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]     221   4e-58
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]          221   4e-58
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]       221   4e-58
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s...   219   1e-57
gi|11496281 kallikrein 13 precursor [Homo sapiens]                    219   2e-57
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot...   216   2e-56
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo...   213   1e-55
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ...   213   1e-55
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ...   213   1e-55
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]                    213   2e-55
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote...   207   9e-54
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei...   207   9e-54
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]                     204   8e-53
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]           199   3e-51
gi|4504875 kallikrein 1 preproprotein [Homo sapiens]                  199   3e-51
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]           197   6e-51
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]           194   6e-50
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]             193   1e-49
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]       192   3e-49
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]        192   3e-49
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho...   187   1e-47
gi|71834855 prostate specific antigen isoform 4 preproprotein [H...   170   1e-42

>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
           sapiens]
          Length = 253

 Score =  530 bits (1364), Expect = e-151
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV 60
           MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
Sbjct: 1   MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV 60

Query: 61  NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS 120
           NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
Sbjct: 61  NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS 120

Query: 121 QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180
           QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
Sbjct: 121 QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180

Query: 181 KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240
           KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
Sbjct: 181 KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240

Query: 241 FTKWINDTMKKHR 253
           FTKWINDTMKKHR
Sbjct: 241 FTKWINDTMKKHR 253


>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
           sapiens]
          Length = 253

 Score =  530 bits (1364), Expect = e-151
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV 60
           MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
Sbjct: 1   MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV 60

Query: 61  NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS 120
           NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
Sbjct: 61  NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS 120

Query: 121 QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180
           QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
Sbjct: 121 QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180

Query: 181 KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240
           KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
Sbjct: 181 KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240

Query: 241 FTKWINDTMKKHR 253
           FTKWINDTMKKHR
Sbjct: 241 FTKWINDTMKKHR 253


>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  237 bits (604), Expect = 8e-63
 Identities = 114/238 (47%), Positives = 157/238 (65%), Gaps = 9/238 (3%)

Query: 21  AGEEAQGD----KIIDGAPCARGSHPWQVA-LLSGNQLHCGGVLVNERWVLTAAHCKMNE 75
           AGE+A+ D    +II+G+ C   + PWQ A LL  NQL+CG VLV+ +W+LTAAHC+   
Sbjct: 54  AGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKV 113

Query: 76  YTVHLGSDTLG---DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVR 132
           + V LG  +L    +   Q  +  KS  HPGYS   H NDLML+KLN + R +  V+ + 
Sbjct: 114 FRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPIN 173

Query: 133 LPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAG 192
           + S C   GT C VSGWGTT SP V FP  L C+++ ++S + C   Y   ++++M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233

Query: 193 IPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250
              + +++C GDSGGP+VC G+LQGLVSWG +PC +PN PGVYT +CKFTKWI +T++
Sbjct: 234 -DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290


>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  237 bits (604), Expect = 8e-63
 Identities = 114/238 (47%), Positives = 157/238 (65%), Gaps = 9/238 (3%)

Query: 21  AGEEAQGD----KIIDGAPCARGSHPWQVA-LLSGNQLHCGGVLVNERWVLTAAHCKMNE 75
           AGE+A+ D    +II+G+ C   + PWQ A LL  NQL+CG VLV+ +W+LTAAHC+   
Sbjct: 54  AGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKV 113

Query: 76  YTVHLGSDTLG---DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVR 132
           + V LG  +L    +   Q  +  KS  HPGYS   H NDLML+KLN + R +  V+ + 
Sbjct: 114 FRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPIN 173

Query: 133 LPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAG 192
           + S C   GT C VSGWGTT SP V FP  L C+++ ++S + C   Y   ++++M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233

Query: 193 IPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250
              + +++C GDSGGP+VC G+LQGLVSWG +PC +PN PGVYT +CKFTKWI +T++
Sbjct: 234 -DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290


>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  237 bits (604), Expect = 8e-63
 Identities = 114/238 (47%), Positives = 157/238 (65%), Gaps = 9/238 (3%)

Query: 21  AGEEAQGD----KIIDGAPCARGSHPWQVA-LLSGNQLHCGGVLVNERWVLTAAHCKMNE 75
           AGE+A+ D    +II+G+ C   + PWQ A LL  NQL+CG VLV+ +W+LTAAHC+   
Sbjct: 54  AGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKV 113

Query: 76  YTVHLGSDTLG---DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVR 132
           + V LG  +L    +   Q  +  KS  HPGYS   H NDLML+KLN + R +  V+ + 
Sbjct: 114 FRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPIN 173

Query: 133 LPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAG 192
           + S C   GT C VSGWGTT SP V FP  L C+++ ++S + C   Y   ++++M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233

Query: 193 IPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250
              + +++C GDSGGP+VC G+LQGLVSWG +PC +PN PGVYT +CKFTKWI +T++
Sbjct: 234 -DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290


>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
          Length = 267

 Score =  226 bits (575), Expect = 2e-59
 Identities = 110/250 (44%), Positives = 150/250 (60%), Gaps = 8/250 (3%)

Query: 5   LLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSG--NQLHCGGVLVNE 62
           LL  LQ+L +++      E    +KII G  C R S PWQ ALL+G   +  CGG L++ 
Sbjct: 20  LLTALQVLAIAMTQSQEDE----NKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSG 75

Query: 63  RWVLTAAHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNS 120
           +WV+TAAHC      V LG   L    A  Q ++  +   HP Y+++TH NDLML++L  
Sbjct: 76  QWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQ 135

Query: 121 QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180
            AR+   V+ + +   C  PGT+C VSGWGT +SP   +P+ L CV++ +   + C K Y
Sbjct: 136 PARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAY 195

Query: 181 KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240
              +   M+CAG+P   K++C GDSGGPLVCRG LQGLVSWG   C  P  PGVYT +CK
Sbjct: 196 PRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCK 255

Query: 241 FTKWINDTMK 250
           +  WI +TM+
Sbjct: 256 YRSWIEETMR 265


>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
          Length = 260

 Score =  224 bits (572), Expect = 4e-59
 Identities = 117/243 (48%), Positives = 145/243 (59%), Gaps = 11/243 (4%)

Query: 11  ILLLSLALETAGEE-AQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAA 69
           + LL L    AG   AQ DK++ G  C   S PWQ AL  G QL CGGVLV   WVLTAA
Sbjct: 13  MFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAA 72

Query: 70  HCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYST---QTHVNDLMLVKLNSQARL 124
           HCK  +YTV LG  +L ++    Q I   +S  HP Y++   + H +DLML++L  QA L
Sbjct: 73  HCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASL 132

Query: 125 SSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLL 184
            S VK + L   C  PG  CTVSGWGT TSP   FP  L C +VK+   + C   Y   +
Sbjct: 133 GSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQI 192

Query: 185 ENSMLCAGIPDSKKNA--CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242
            + M+CAG   S K A  C GDSGGPLVC G LQG+ SWG+ PCG+ + PGVYT +C++ 
Sbjct: 193 TDGMVCAG---SSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYL 249

Query: 243 KWI 245
            WI
Sbjct: 250 DWI 252


>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
          Length = 305

 Score =  224 bits (570), Expect = 7e-59
 Identities = 112/228 (49%), Positives = 139/228 (60%), Gaps = 10/228 (4%)

Query: 25  AQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDT 84
           AQ DK++ G  C   S PWQ AL  G QL CGGVLV   WVLTAAHCK  +YTV LG  +
Sbjct: 73  AQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHS 132

Query: 85  LGDRRA--QRIKASKSFRHPGYST---QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP 139
           L ++    Q I   +S  HP Y++   + H +DLML++L  QA L S VK + L   C  
Sbjct: 133 LQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQ 192

Query: 140 PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199
           PG  CTVSGWGT TSP   FP  L C +VK+   + C   Y   + + M+CAG   S K 
Sbjct: 193 PGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAG---SSKG 249

Query: 200 A--CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245
           A  C GDSGGPLVC G LQG+ SWG+ PCG+ + PGVYT +C++  WI
Sbjct: 250 ADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWI 297


>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
          Length = 250

 Score =  221 bits (564), Expect = 4e-58
 Identities = 108/250 (43%), Positives = 149/250 (59%), Gaps = 9/250 (3%)

Query: 9   LQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
           LQ++LL+LA    G E    +II G  C   S PWQ AL    +L CG  L+  RW+LTA
Sbjct: 4   LQLILLALATGLVGGET---RIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 60

Query: 69  AHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYST----QTHVNDLMLVKLNSQA 122
           AHC    Y VHLG   L       Q   A++SF HPG++     + H ND+MLVK+ S  
Sbjct: 61  AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 120

Query: 123 RLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD 182
            ++  V+ + L SRC   GT+C +SGWG+T+SP +  P  L C ++ +I  Q C   Y  
Sbjct: 121 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 180

Query: 183 LLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242
            + ++M+CA + +  K++C GDSGGPLVC  +LQG++SWG  PC     PGVYT+VCK+ 
Sbjct: 181 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 240

Query: 243 KWINDTMKKH 252
            WI +TMK +
Sbjct: 241 DWIQETMKNN 250


>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
          Length = 282

 Score =  221 bits (564), Expect = 4e-58
 Identities = 108/250 (43%), Positives = 149/250 (59%), Gaps = 9/250 (3%)

Query: 9   LQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
           LQ++LL+LA    G E    +II G  C   S PWQ AL    +L CG  L+  RW+LTA
Sbjct: 36  LQLILLALATGLVGGET---RIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92

Query: 69  AHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYST----QTHVNDLMLVKLNSQA 122
           AHC    Y VHLG   L       Q   A++SF HPG++     + H ND+MLVK+ S  
Sbjct: 93  AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 152

Query: 123 RLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD 182
            ++  V+ + L SRC   GT+C +SGWG+T+SP +  P  L C ++ +I  Q C   Y  
Sbjct: 153 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 212

Query: 183 LLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242
            + ++M+CA + +  K++C GDSGGPLVC  +LQG++SWG  PC     PGVYT+VCK+ 
Sbjct: 213 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 272

Query: 243 KWINDTMKKH 252
            WI +TMK +
Sbjct: 273 DWIQETMKNN 282


>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
          Length = 250

 Score =  221 bits (564), Expect = 4e-58
 Identities = 108/250 (43%), Positives = 149/250 (59%), Gaps = 9/250 (3%)

Query: 9   LQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
           LQ++LL+LA    G E    +II G  C   S PWQ AL    +L CG  L+  RW+LTA
Sbjct: 4   LQLILLALATGLVGGET---RIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 60

Query: 69  AHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYST----QTHVNDLMLVKLNSQA 122
           AHC    Y VHLG   L       Q   A++SF HPG++     + H ND+MLVK+ S  
Sbjct: 61  AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 120

Query: 123 RLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD 182
            ++  V+ + L SRC   GT+C +SGWG+T+SP +  P  L C ++ +I  Q C   Y  
Sbjct: 121 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 180

Query: 183 LLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242
            + ++M+CA + +  K++C GDSGGPLVC  +LQG++SWG  PC     PGVYT+VCK+ 
Sbjct: 181 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 240

Query: 243 KWINDTMKKH 252
            WI +TMK +
Sbjct: 241 DWIQETMKNN 250


>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
           sapiens]
          Length = 254

 Score =  219 bits (559), Expect = 1e-57
 Identities = 110/240 (45%), Positives = 151/240 (62%), Gaps = 7/240 (2%)

Query: 16  LALETAGEEAQGD--KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKM 73
           L L  AG    G   +II+G  C+  S PWQ AL+  N+L C GVLV+ +WVL+AAHC  
Sbjct: 15  LILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ 74

Query: 74  NEYTVHLGSDTLG---DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKK 130
           N YT+ LG  +L    +  +Q ++AS S RHP Y+     NDLML+KL+     S  ++ 
Sbjct: 75  NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRS 134

Query: 131 VRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLC 190
           + + S+C   G +C VSGWG   +  +  P+ L CV+V ++S + C+K+Y  L   SM C
Sbjct: 135 ISIASQCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFC 192

Query: 191 AGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250
           AG    +K++CNGDSGGPL+C G LQGLVS+G  PCGQ   PGVYT +CKFT+WI  T++
Sbjct: 193 AGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252


>gi|11496281 kallikrein 13 precursor [Homo sapiens]
          Length = 277

 Score =  219 bits (558), Expect = 2e-57
 Identities = 116/263 (44%), Positives = 161/263 (61%), Gaps = 18/263 (6%)

Query: 8   PLQILLLSLALETAGEEAQ-GDKIID----------GAPCARGSHPWQVALLSGNQLHCG 56
           PL +++ SL L  +G  +Q   K+++          G  C   S PWQ ALL   +L CG
Sbjct: 3   PLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCG 62

Query: 57  GVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYS-TQTHVN-- 111
           GVLV+ +WVLTAAHC      V+LG   LG   A  Q  +   S  HP Y  + TH+N  
Sbjct: 63  GVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHD 122

Query: 112 -DLMLVKLNSQARLSSMVKKVRLPSRCE-PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVK 169
            D+ML++L S  +L+  ++ + L       PGTTC VSGWGTTTSP V +P  L C +++
Sbjct: 123 HDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQ 182

Query: 170 LISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQP 229
           L S ++C +VY   + ++MLCAG  +  K++C GDSGGPLVC  TL G+VSWG FPCGQP
Sbjct: 183 LRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQP 242

Query: 230 NDPGVYTQVCKFTKWINDTMKKH 252
           + PGVYT+V ++  WI +T++K+
Sbjct: 243 DRPGVYTRVSRYVLWIRETIRKY 265


>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
           [Homo sapiens]
          Length = 256

 Score =  216 bits (550), Expect = 2e-56
 Identities = 112/254 (44%), Positives = 146/254 (57%), Gaps = 13/254 (5%)

Query: 12  LLLSLALETAGEEAQ-GDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAH 70
           LLL+L+   A   AQ GDK+++G  CA  S PWQVAL    + +CG  L++  WVL+AAH
Sbjct: 3   LLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62

Query: 71  CKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMV 128
           C+     V LG   L  R    Q    S+   HP Y  ++H ND+ML++L   ARL+  V
Sbjct: 63  CQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQV 122

Query: 129 KKVRLPSRCEPPGTTCTVSGWG--------TTTSP--DVTFPSDLMCVDVKLISPQDCTK 178
           +   LP+RC  PG  C VSGWG        T  SP   V+ P  L C ++ +IS   C K
Sbjct: 123 RPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDK 182

Query: 179 VYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQV 238
            Y   L N+M+CAG       +C GDSGGPLVC G LQG+VSWG  PC     PGVYT+V
Sbjct: 183 SYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKV 242

Query: 239 CKFTKWINDTMKKH 252
           C + +WI +TMK++
Sbjct: 243 CHYLEWIRETMKRN 256


>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
           sapiens]
          Length = 276

 Score =  213 bits (542), Expect = 1e-55
 Identities = 108/264 (40%), Positives = 154/264 (58%), Gaps = 14/264 (5%)

Query: 2   ARSLLLPLQILLLSLALETAGEEAQGDKIID----GAPCARGSHPWQVALLSGNQLHCGG 57
           AR+L   L +L+  L    A    Q D  +D    G+PCARGS PWQV+L +G   HC G
Sbjct: 14  ARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAG 73

Query: 58  VLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIK-ASKSFRHPGYST--------QT 108
           VLV++ WVLTAAHC        +G D L   + ++++  ++S  HP Y          +T
Sbjct: 74  VLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPKYHQGSGPILPRRT 133

Query: 109 HVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDV 168
             +DLML+KL     L   V+ ++LP RC  PG  C V+GWGTT +  V +   L C  +
Sbjct: 134 DEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSI 193

Query: 169 KLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQ 228
            ++SP++C   Y  ++ N+M+CAG+ D  ++ C  DSGGPLVC  TLQG++SWG +PCG 
Sbjct: 194 TILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGS 252

Query: 229 PNDPGVYTQVCKFTKWINDTMKKH 252
              P VYTQ+CK+  WIN  ++ +
Sbjct: 253 AQHPAVYTQICKYMSWINKVIRSN 276


>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
           sapiens]
          Length = 276

 Score =  213 bits (542), Expect = 1e-55
 Identities = 108/264 (40%), Positives = 154/264 (58%), Gaps = 14/264 (5%)

Query: 2   ARSLLLPLQILLLSLALETAGEEAQGDKIID----GAPCARGSHPWQVALLSGNQLHCGG 57
           AR+L   L +L+  L    A    Q D  +D    G+PCARGS PWQV+L +G   HC G
Sbjct: 14  ARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAG 73

Query: 58  VLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIK-ASKSFRHPGYST--------QT 108
           VLV++ WVLTAAHC        +G D L   + ++++  ++S  HP Y          +T
Sbjct: 74  VLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPKYHQGSGPILPRRT 133

Query: 109 HVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDV 168
             +DLML+KL     L   V+ ++LP RC  PG  C V+GWGTT +  V +   L C  +
Sbjct: 134 DEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSI 193

Query: 169 KLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQ 228
            ++SP++C   Y  ++ N+M+CAG+ D  ++ C  DSGGPLVC  TLQG++SWG +PCG 
Sbjct: 194 TILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGS 252

Query: 229 PNDPGVYTQVCKFTKWINDTMKKH 252
              P VYTQ+CK+  WIN  ++ +
Sbjct: 253 AQHPAVYTQICKYMSWINKVIRSN 276


>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
           sapiens]
          Length = 276

 Score =  213 bits (542), Expect = 1e-55
 Identities = 108/264 (40%), Positives = 154/264 (58%), Gaps = 14/264 (5%)

Query: 2   ARSLLLPLQILLLSLALETAGEEAQGDKIID----GAPCARGSHPWQVALLSGNQLHCGG 57
           AR+L   L +L+  L    A    Q D  +D    G+PCARGS PWQV+L +G   HC G
Sbjct: 14  ARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAG 73

Query: 58  VLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIK-ASKSFRHPGYST--------QT 108
           VLV++ WVLTAAHC        +G D L   + ++++  ++S  HP Y          +T
Sbjct: 74  VLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPKYHQGSGPILPRRT 133

Query: 109 HVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDV 168
             +DLML+KL     L   V+ ++LP RC  PG  C V+GWGTT +  V +   L C  +
Sbjct: 134 DEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSI 193

Query: 169 KLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQ 228
            ++SP++C   Y  ++ N+M+CAG+ D  ++ C  DSGGPLVC  TLQG++SWG +PCG 
Sbjct: 194 TILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGS 252

Query: 229 PNDPGVYTQVCKFTKWINDTMKKH 252
              P VYTQ+CK+  WIN  ++ +
Sbjct: 253 AQHPAVYTQICKYMSWINKVIRSN 276


>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
          Length = 248

 Score =  213 bits (541), Expect = 2e-55
 Identities = 115/258 (44%), Positives = 152/258 (58%), Gaps = 16/258 (6%)

Query: 1   MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV 60
           M  S+ L L +L LS        +A   KI +G  C R S PWQV L  G  L CGGVL+
Sbjct: 1   MGLSIFLLLCVLGLS--------QAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLI 52

Query: 61  NERWVLTAAHCKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGY--STQTHVNDLMLV 116
           + RWVLTAAHC  + Y V LG  +L   D   Q   +  S  HPGY  ++ +H +DL L+
Sbjct: 53  DHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLL 112

Query: 117 KLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC 176
           +L    R++S V+ + LP+ C   GT C VSGWG T  P   FP  L C+++ ++S   C
Sbjct: 113 RLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATC 172

Query: 177 TKVYKDLLENSMLCA-GIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTF-PCGQPNDPGV 234
             VY   + ++M+CA G+P   ++AC GDSGGPLVC G LQGLVSWG+  PCGQ   PGV
Sbjct: 173 HGVYPGRITSNMVCAGGVPG--QDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGV 230

Query: 235 YTQVCKFTKWINDTMKKH 252
           YT +CK+  WI   M+ +
Sbjct: 231 YTYICKYVDWIRMIMRNN 248


>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
           [Homo sapiens]
          Length = 244

 Score =  207 bits (526), Expect = 9e-54
 Identities = 99/241 (41%), Positives = 142/241 (58%), Gaps = 4/241 (1%)

Query: 12  LLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC 71
           L++ L+L  A    + +K++ G PC + SHP+Q AL +   L CGGVL++  WVLTAAHC
Sbjct: 4   LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63

Query: 72  KMNEYTVHLGSDTLGDRRAQRIKAS--KSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVK 129
           K     V LG   L  R + + ++S  ++  HP Y   +H  D+ML++L   A+LS +++
Sbjct: 64  KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQ 123

Query: 130 KVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSML 189
            + L   C    T+C + GWG T   D  FP  + C  + L+S ++C   Y   +  +ML
Sbjct: 124 PLPLERDCSANTTSCHILGWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQITQNML 181

Query: 190 CAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
           CAG     K++C GDSGGPLVC   L+GLVSWG  PCG    PGVYT VC++T WI  T+
Sbjct: 182 CAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241

Query: 250 K 250
           +
Sbjct: 242 Q 242


>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
           [Homo sapiens]
          Length = 244

 Score =  207 bits (526), Expect = 9e-54
 Identities = 99/241 (41%), Positives = 142/241 (58%), Gaps = 4/241 (1%)

Query: 12  LLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC 71
           L++ L+L  A    + +K++ G PC + SHP+Q AL +   L CGGVL++  WVLTAAHC
Sbjct: 4   LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63

Query: 72  KMNEYTVHLGSDTLGDRRAQRIKAS--KSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVK 129
           K     V LG   L  R + + ++S  ++  HP Y   +H  D+ML++L   A+LS +++
Sbjct: 64  KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQ 123

Query: 130 KVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSML 189
            + L   C    T+C + GWG T   D  FP  + C  + L+S ++C   Y   +  +ML
Sbjct: 124 PLPLERDCSANTTSCHILGWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQITQNML 181

Query: 190 CAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
           CAG     K++C GDSGGPLVC   L+GLVSWG  PCG    PGVYT VC++T WI  T+
Sbjct: 182 CAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241

Query: 250 K 250
           +
Sbjct: 242 Q 242


>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
          Length = 254

 Score =  204 bits (518), Expect = 8e-53
 Identities = 112/248 (45%), Positives = 146/248 (58%), Gaps = 16/248 (6%)

Query: 1   MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV 60
           M  S+ L L +L LS        +A   KI +G  C R S PWQV L  G  L CGGVL+
Sbjct: 1   MGLSIFLLLCVLGLS--------QAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLI 52

Query: 61  NERWVLTAAHCKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGY--STQTHVNDLMLV 116
           + RWVLTAAHC  + Y V LG  +L   D   Q   +  S  HPGY  ++ +H +DL L+
Sbjct: 53  DHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLL 112

Query: 117 KLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC 176
           +L    R++S V+ + LP+ C   GT C VSGWG T  P   FP  L C+++ ++S   C
Sbjct: 113 RLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATC 172

Query: 177 TKVYKDLLENSMLCA-GIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTF-PCGQPNDPGV 234
             VY   + ++M+CA G+P   ++AC GDSGGPLVC G LQGLVSWG+  PCGQ   PGV
Sbjct: 173 HGVYPGRITSNMVCAGGVPG--QDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGV 230

Query: 235 YTQVCKFT 242
           YT +C  T
Sbjct: 231 YTYICNST 238


>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
          Length = 247

 Score =  199 bits (505), Expect = 3e-51
 Identities = 99/241 (41%), Positives = 141/241 (58%), Gaps = 4/241 (1%)

Query: 11  ILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAH 70
           ++L  +A   A      DKI+ G  C   S P+QV+L SG    CGG L+NE+WV++A H
Sbjct: 5   LILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHF-CGGSLINEQWVVSAGH 63

Query: 71  CKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMV 128
           C  +   V LG   +   +   Q I A+K  RHP Y  +T  ND+ML+KL+S+A +++ V
Sbjct: 64  CYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARV 123

Query: 129 KKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSM 188
             + LP+     GT C +SGWG T S    +P +L C+D  ++S   C   Y   + ++M
Sbjct: 124 STISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNM 183

Query: 189 LCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248
            C G  +  K++C GDSGGP+VC G LQG+VSWG   C Q N PGVYT+V  + KWI +T
Sbjct: 184 FCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNT 242

Query: 249 M 249
           +
Sbjct: 243 I 243


>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
          Length = 262

 Score =  199 bits (505), Expect = 3e-51
 Identities = 104/258 (40%), Positives = 146/258 (56%), Gaps = 17/258 (6%)

Query: 12  LLLSLALETAGEEAQG---DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
           L+L LAL   G  A      +I+ G  C + S PWQ AL   +   CGG+LV+ +WVLTA
Sbjct: 4   LVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTA 63

Query: 69  AHCKMNEYTVHLGSDTLGD--RRAQRIKASKSFRHPGYST-----------QTHVNDLML 115
           AHC  + Y + LG   L D    AQ +  S+SF HPG++            + + +DLML
Sbjct: 64  AHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLML 123

Query: 116 VKLNSQA-RLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQ 174
           ++L   A  ++  VK V LP+     G+TC  SGWG+    + +FP DL CVD+K++   
Sbjct: 124 LRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPND 183

Query: 175 DCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGV 234
           +C K +   + + MLC G  +  K+ C GDSGGPL+C G LQG+ SWG  PCG PN P V
Sbjct: 184 ECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSV 243

Query: 235 YTQVCKFTKWINDTMKKH 252
             +V  + KWI DT+ ++
Sbjct: 244 AVRVLSYVKWIEDTIAEN 261


>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
          Length = 261

 Score =  197 bits (502), Expect = 6e-51
 Identities = 105/254 (41%), Positives = 141/254 (55%), Gaps = 16/254 (6%)

Query: 12  LLLSLALE---TAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
           L+LS+AL    T        +I+ G  C + S PWQVA+ S    HCGGVLV+ +WVLTA
Sbjct: 4   LVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTA 63

Query: 69  AHCKMNEYTVHLGSDTLGDRR--AQRIKASKSFRHPGYST-----------QTHVNDLML 115
           AHC      V LG   L +     QR+  S SF HP Y+            +   +DLML
Sbjct: 64  AHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLML 123

Query: 116 VKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQD 175
           ++L+  A+++ +VK + LP++    GTTC  SGWG+    +   P  L CV + L+S   
Sbjct: 124 LRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDM 183

Query: 176 CTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVY 235
           C + Y + +   MLCAG+    K+ C GDSGGPLVC G LQG+ SWG  PC  P  P VY
Sbjct: 184 CARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVY 243

Query: 236 TQVCKFTKWINDTM 249
           T+V  + KWI DT+
Sbjct: 244 TKVVHYRKWIKDTI 257


>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
          Length = 247

 Score =  194 bits (493), Expect = 6e-50
 Identities = 98/243 (40%), Positives = 142/243 (58%), Gaps = 4/243 (1%)

Query: 9   LQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
           L ++L  +A   A      DKI+ G  C   S P+QV+L SG    CGG L++E+WV++A
Sbjct: 3   LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVVSA 61

Query: 69  AHCKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSS 126
            HC  +   V LG   +   +   Q I A+K  RHP Y+++T  ND++L+KL+S A ++S
Sbjct: 62  GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINS 121

Query: 127 MVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLEN 186
            V  + LP+     GT   +SGWG T S    +P +L C+D  ++S  +C   Y   + N
Sbjct: 122 RVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITN 181

Query: 187 SMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246
           +M C G  +  K++C GDSGGP+V  G LQG+VSWG + C Q N PGVYT+V  +  WI 
Sbjct: 182 NMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIK 240

Query: 247 DTM 249
           DT+
Sbjct: 241 DTI 243


>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
          Length = 250

 Score =  193 bits (491), Expect = 1e-49
 Identities = 97/245 (39%), Positives = 133/245 (54%), Gaps = 6/245 (2%)

Query: 12  LLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC 71
           LL +L    AG      + I    C   S PWQ  L    +L CG  L+++RW+LTAAHC
Sbjct: 5   LLCALLSLLAGHGWADTRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHC 64

Query: 72  KMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGY----STQTHVNDLMLVKLNSQARLS 125
           +     V LG   L   +   Q  + +  F HPG+    S   H +D+ML++L  QARLS
Sbjct: 65  RKPYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLS 124

Query: 126 SMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLE 185
             V+ + L   C  PG  C +SGWG  +SP   FP  L C ++ ++  + C   Y   + 
Sbjct: 125 PAVQPLNLSQTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHIS 184

Query: 186 NSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245
           +SMLCAG+ +  + +C GDSGGPLVC GTL G+VS G  PC +P  P VYT VC +  WI
Sbjct: 185 DSMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWI 244

Query: 246 NDTMK 250
            + M+
Sbjct: 245 QEIME 249


>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
          Length = 304

 Score =  192 bits (487), Expect = 3e-49
 Identities = 95/224 (42%), Positives = 133/224 (59%), Gaps = 4/224 (1%)

Query: 28  DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG- 86
           DKI+ G  C   S P+QV+L SG+   CGG L++E+WV++AAHC      V LG   +  
Sbjct: 79  DKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKV 137

Query: 87  -DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145
            +   Q I A+K  RHP Y+  T  ND+ML+KL+S A +++ V  + LP+     GT C 
Sbjct: 138 LEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECL 197

Query: 146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDS 205
           +SGWG T S    +P +L C+D  +++  +C   Y   + NSM C G  +  K++C  DS
Sbjct: 198 ISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDS 257

Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
           GGP+VC G LQG+VSWG   C   N PGVYT+V  +  WI DT+
Sbjct: 258 GGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTI 300


>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
          Length = 247

 Score =  192 bits (487), Expect = 3e-49
 Identities = 95/224 (42%), Positives = 133/224 (59%), Gaps = 4/224 (1%)

Query: 28  DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG- 86
           DKI+ G  C   S P+QV+L SG+   CGG L++E+WV++AAHC      V LG   +  
Sbjct: 22  DKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKV 80

Query: 87  -DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145
            +   Q I A+K  RHP Y+  T  ND+ML+KL+S A +++ V  + LP+     GT C 
Sbjct: 81  LEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECL 140

Query: 146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDS 205
           +SGWG T S    +P +L C+D  +++  +C   Y   + NSM C G  +  K++C  DS
Sbjct: 141 ISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDS 200

Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
           GGP+VC G LQG+VSWG   C   N PGVYT+V  +  WI DT+
Sbjct: 201 GGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTI 243


>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
           sapiens]
          Length = 261

 Score =  187 bits (474), Expect = 1e-47
 Identities = 98/234 (41%), Positives = 132/234 (56%), Gaps = 13/234 (5%)

Query: 29  KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--G 86
           +I+ G  C + S PWQV + S  +  CGGVLV+ +WVLTAAHC  N+  + LG  +L   
Sbjct: 24  RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83

Query: 87  DRRAQRIKASKSFRHPGYSTQTHVN-----------DLMLVKLNSQARLSSMVKKVRLPS 135
           +   Q  + S SF HP Y      N           DLML++L+  A L+  VK + LP+
Sbjct: 84  EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143

Query: 136 RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPD 195
           +    GTTC  SGWG+    +   P  L CVD+ +IS   C +V+   +   MLCAG   
Sbjct: 144 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 203

Query: 196 SKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
             K+ C+GDSGGPLVC G LQG+ SWG+ PC  P  P +YT+V  + KWI DT+
Sbjct: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257


>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
           sapiens]
          Length = 218

 Score =  170 bits (431), Expect = 1e-42
 Identities = 89/221 (40%), Positives = 120/221 (54%), Gaps = 30/221 (13%)

Query: 29  KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDR 88
           +I+ G  C + S PWQV + S  +  CGGVLV+ +WVLTAAHC                 
Sbjct: 24  RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHC----------------- 66

Query: 89  RAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSG 148
                      R PG  +    +DLML++L+  A L+  VK + LP++    GTTC  SG
Sbjct: 67  ----------IRKPGDDSS---HDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASG 113

Query: 149 WGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGP 208
           WG+    +   P  L CVD+ +IS   C +V+   +   MLCAG     K+ C+GDSGGP
Sbjct: 114 WGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGP 173

Query: 209 LVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
           LVC G LQG+ SWG+ PC  P  P +YT+V  + KWI DT+
Sbjct: 174 LVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 214


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,711,592
Number of Sequences: 37866
Number of extensions: 498972
Number of successful extensions: 1669
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 168
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1057
Number of HSP's gapped (non-prelim): 196
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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