Search of human proteins with 13273313

Search of human proteins with 13273313

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13273313 cytosolic beta-glucosidase isoform a [Homo sapiens]
         (469 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13273313 cytosolic beta-glucosidase isoform a [Homo sapiens]       987   0.0  
gi|32481206 lactase-phlorizin hydrolase preproprotein [Homo sapi...   454   e-127
gi|110681710 lactase-like [Homo sapiens]                              424   e-118
gi|24497614 klotho [Homo sapiens]                                     360   2e-99
gi|28376633 klotho beta [Homo sapiens]                                320   1e-87
gi|190360571 cytosolic beta-glucosidase isoform b [Homo sapiens]      212   5e-55

>gi|13273313 cytosolic beta-glucosidase isoform a [Homo sapiens]
          Length = 469

 Score =  987 bits (2552), Expect = 0.0
 Identities = 469/469 (100%), Positives = 469/469 (100%)

Query: 1   MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
           MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE
Sbjct: 1   MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60

Query: 61  EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
           EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH
Sbjct: 61  EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120

Query: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
           FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180

Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240
           PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ
Sbjct: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240

Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300
           EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT
Sbjct: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300

Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360
           ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI
Sbjct: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360

Query: 361 KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL 420
           KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL
Sbjct: 361 KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL 420

Query: 421 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469
           DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL
Sbjct: 421 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469


>gi|32481206 lactase-phlorizin hydrolase preproprotein [Homo sapiens]
          Length = 1927

 Score =  454 bits (1167), Expect = e-127
 Identities = 216/463 (46%), Positives = 297/463 (64%), Gaps = 1/463 (0%)

Query: 3    FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
            F   F W  +++AYQ+EG WDADGKGP +WD FTH  G  V  N TGD+AC SY   + D
Sbjct: 903  FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962

Query: 63   LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
            L  ++ L +  YRFS+SWSR+ P G    IN  G+DYYN++I+ L+ + + P+VTL+H+D
Sbjct: 963  LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022

Query: 123  LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
            LPQ L+D GGW + A+I+ FD YA FCF TFGDRVK W+T NE   L+ + Y  G FPPG
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082

Query: 183  IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEA 242
            +   G   Y+ AH +IKAHAR +H+YD  +R++QKG++SLSL   W EP  P    D EA
Sbjct: 1083 VKDPGWAPYRIAHAVIKAHARVYHTYDEKYRQEQKGVISLSLSTHWAEPKSPGVPRDVEA 1142

Query: 243  AKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTAD 302
            A R + F L  FA PIF +GDYP+ +K ++ + S+ Q   +SRLP FTEEEK+ I+ TAD
Sbjct: 1143 ADRMLQFSLGWFAHPIFRNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFIRATAD 1202

Query: 303  FFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKD 362
             F +  Y +R+++++  +        D E+    DPSW +       PWG  +LL +IK+
Sbjct: 1203 VFCLNTYYSRIVQHKTPRLNPPSYEDDQEMAEEEDPSWPSTAMNRAAPWGTRRLLNWIKE 1262

Query: 363  TYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDN 422
             Y +  IYITENG   ++P   +DT R  Y +    E  KA +LD ++L+ Y AWSL+DN
Sbjct: 1263 EYGDIPIYITENGVGLTNP-NTEDTDRIFYHKTYINEALKAYRLDGIDLRGYVAWSLMDN 1321

Query: 423  FEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465
            FEW  GY+ +FGL+HVDF +  RPR    SA+ Y ++I NNG+
Sbjct: 1322 FEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVITNNGM 1364



 Score =  446 bits (1148), Expect = e-125
 Identities = 222/466 (47%), Positives = 302/466 (64%), Gaps = 7/466 (1%)

Query: 3    FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
            FP GF W+AA+AAYQ+EG W ADGKG  +WDTF+H    RV  +  GDVAC SY    ED
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHTP-LRVENDAIGDVACDSYHKIAED 1435

Query: 63   LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
            L  ++ LG++HYRFS+SWSR+LPDGTT +IN+ G++YY ++ID LL   + P VT+YH+D
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495

Query: 123  LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
            LPQTL+D GGW +E I++ F +YA   F   GD+VK WIT+NE  V++   Y  G   PG
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555

Query: 183  IPHF-GTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQE 241
            + +  GT  Y   HNLIKAHA +WH Y+ ++R  Q G++S+++ + W EP DP++  D E
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITISSDWAEPRDPSNQEDVE 1615

Query: 242  AAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTA 301
            AA+R + F    FA PIF +GDY EV+K++I   S   G   SRLPEFTE EK+ I GT 
Sbjct: 1616 AARRYVQFMGGWFAHPIFKNGDYNEVMKTRIRDRSLAAGLNKSRLPEFTESEKRRINGTY 1675

Query: 302  DFFAVQYYTTRLIKYQENKKGELGILQ-DAEIEFFPDPSWKNVD--WIYVVPWGVCKLLK 358
            DFF   +YTT ++ Y  N    +     D  +    D SW +    W+ + P+G  ++L 
Sbjct: 1676 DFFGFNHYTT-VLAYNLNYATAISSFDADRGVASIADRSWPDSGSFWLKMTPFGFRRILN 1734

Query: 359  YIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWS 418
            ++K+ YN+P IY+TENG  Q +   L+DT R  Y R    E  KA+Q DKV+L+ Y  WS
Sbjct: 1735 WLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQ-DKVDLRGYTVWS 1793

Query: 419  LLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNG 464
             +DNFEW  G+S RFGL  V++ DP+ PR+P  SAK YA ++R NG
Sbjct: 1794 AMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVRCNG 1839



 Score =  373 bits (957), Expect = e-103
 Identities = 197/474 (41%), Positives = 277/474 (58%), Gaps = 21/474 (4%)

Query: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTF----THQGGERVFKNQTGDVACGSYTL 58
           FP GF W A+T A+ VEGGW   G+G  +WD      T +G        T +VA  SY  
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDPRRPLNTTEG------QATLEVASDSYHK 435

Query: 59  WEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTL 118
              D+  +  L    Y+FS+SWSR+ P G     +  G+ YYNK+ID L   G+ P+ TL
Sbjct: 436 VASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATL 495

Query: 119 YHFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGM 178
           +H+DLPQ L+D GGW +E+++++F  YA FCFSTFGDRVK W+T +E  V+S   Y  G 
Sbjct: 496 FHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQ 555

Query: 179 FPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVS 238
            PPGI   G   ++ AH ++KAHAR+WH Y+S  R +Q+G V + L + W EP  P    
Sbjct: 556 HPPGISDPGVASFKVAHLVLKAHARTWHHYNSHHRPQQQGHVGIVLNSDWAEPLSPERPE 615

Query: 239 DQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIK 298
           D  A++R + F L  FA P+F+DGDYP  +++QI  M+++  +P ++LPEFTE EK+++K
Sbjct: 616 DLRASERFLHFMLGWFAHPVFVDGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLLK 675

Query: 299 GTADFFAVQYYTTRLIKYQENKK-----GELGILQDAEIEFFPDPSWKNVDWIYVVPWGV 353
           G+ADF  + +YT+RLI              +G         +P  S     WI VVPWG+
Sbjct: 676 GSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFSQHVNHVWPQTS---SSWIRVVPWGI 732

Query: 354 CKLLKYIKDTY--NNPVIYITENGFPQSDPAPL-DDTQRWEYFRQTFQELFKAIQLDKVN 410
            +LL+++   Y      IY+  NG P  +   L DD+ R +YF Q   E+ KAI+ D V+
Sbjct: 733 RRLLQFVSLEYTRGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVD 792

Query: 411 LQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNG 464
           ++ Y A SL+D FE   GYS RFGL HV+F D ++ R P  SA  +  II  NG
Sbjct: 793 VRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSIIEKNG 846



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 33/95 (34%), Positives = 54/95 (56%), Gaps = 4/95 (4%)

Query: 71  LTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQ 130
           +THY+  LSW++LLP G+T   ++K +  Y +++  L    + P+V L+H  LP +   +
Sbjct: 84  ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRR 143

Query: 131 GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165
               +EA  + F  YA F F +FGD V  W T ++
Sbjct: 144 ----TEAFADLFADYATFAFHSFGDLVGIWFTFSD 174


>gi|110681710 lactase-like [Homo sapiens]
          Length = 567

 Score =  424 bits (1089), Expect = e-118
 Identities = 213/469 (45%), Positives = 296/469 (63%), Gaps = 10/469 (2%)

Query: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
           FP GF W   ++AYQ EG WD DGKGP +WD FTH G  +V  N+T DVAC  Y   +ED
Sbjct: 37  FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQED 96

Query: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGF-INQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121
           +  +++L + HYRFSLSW RLLP G     +N+KGI++Y+ +ID LL + +TPIVTL+H+
Sbjct: 97  IILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHW 156

Query: 122 DLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
           DLPQ L+ + GGW + ++   F  YA  CF  FGDRVK WIT ++   ++   Y+ G   
Sbjct: 157 DLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHHA 216

Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240
           PG+   GTG Y+AAH++IKAHA++WHSY++ +R KQ+G+V +SL   W EP D ++  D 
Sbjct: 217 PGLKLRGTGLYKAAHHIIKAHAKAWHSYNTTWRSKQQGLVGISLNCDWGEPVDISNPKDL 276

Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300
           EAA+R + F L  FA PI+  GDYP+V+K  I   S +QG   SRLP F+ +EK  IKGT
Sbjct: 277 EAAERYLQFCLGWFANPIYA-GDYPQVMKDYIGRKSAEQGLEMSRLPVFSLQEKSYIKGT 335

Query: 301 ADFFAVQYYTTRLIKYQENKKGELG--ILQDAEIEFFPDPSWKNV--DWIYVVPWGVCKL 356
           +DF  + ++TTR I  + N     G     D ++    DP+W ++   W+Y VPWG  +L
Sbjct: 336 SDFLGLGHFTTRYIT-ERNYPSRQGPSYQNDRDLIELVDPNWPDLGSKWLYSVPWGFRRL 394

Query: 357 LKYIKDTYNNPVIYITENGFPQS-DPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYC 415
           L + +  Y +P IY+ ENG  Q      L D  R +Y +    E+ KAI+ D  N++ Y 
Sbjct: 395 LNFAQTQYGDPPIYVMENGASQKFHCTQLCDEWRIQYLKGYINEMLKAIK-DGANIKGYT 453

Query: 416 AWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNG 464
           +WSLLD FEW +GYS R+G ++V+F D  +PR P  S + Y KII  NG
Sbjct: 454 SWSLLDKFEWEKGYSDRYGFYYVEFNDRNKPRYPKASVQYYKKIIIANG 502


>gi|24497614 klotho [Homo sapiens]
          Length = 1012

 Score =  360 bits (924), Expect = 2e-99
 Identities = 200/480 (41%), Positives = 278/480 (57%), Gaps = 53/480 (11%)

Query: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQ---------------GGERVFKNQ 47
           FP GF WA  +AAYQ EGGW   GKG  +WDTFTH                G     +  
Sbjct: 61  FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120

Query: 48  TGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDL 107
           TGDVA  SY     D + +++LG+THYRFS+SW+R+LP+G+ G  N++G+ YY ++++ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180

Query: 108 LKNGVTPIVTLYHFDLPQTLED-QGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEA 166
            + GV P+VTLYH+DLPQ L+D  GGW + A+ + F  YA+ CF  FG +VK WITI+  
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240

Query: 167 NVLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFA 226
            V++   Y  G   PGI      GY  AHNL+ AHA+ WH Y++ FR  Q G VS++L +
Sbjct: 241 YVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSS 300

Query: 227 VWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRL 286
            W+ P      S +E  K ++ F L  FAKP+FIDGDYPE +K+ ++S+          L
Sbjct: 301 HWINPRRMTDHSIKECQK-SLDFVLGWFAKPVFIDGDYPESMKNNLSSI----------L 349

Query: 287 PEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEF--FPDPSWKNVD 344
           P+FTE EKK IKGTADFFA+ +  T  + +Q         L D  ++F     P+ +   
Sbjct: 350 PDFTESEKKFIKGTADFFALCFGPT--LSFQ---------LLDPHMKFRQLESPNLR--- 395

Query: 345 WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAI 404
                     +LL +I   +N+P I+I ENG+  S     DD +   Y ++   E  KAI
Sbjct: 396 ----------QLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAI 445

Query: 405 QLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNG 464
           +LD V++  Y AWSL+D FEW++GYS R GLF+VDF    +  +P +SA  Y K+I  NG
Sbjct: 446 KLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNG 505



 Score =  233 bits (594), Expect = 3e-61
 Identities = 145/418 (34%), Positives = 216/418 (51%), Gaps = 43/418 (10%)

Query: 53  CGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGV 112
           C  +   +  +  ++++ +TH+RFSL W+ +LP G    +N   + YY  +  +L++  +
Sbjct: 572 CVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNI 631

Query: 113 TPIVTLY-----HFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEAN 167
           TP+V L+     +  LP+ L  QG W +     +F +YA+ CF   G  VK WIT+NE  
Sbjct: 632 TPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNE-- 689

Query: 168 VLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAV 227
                           P+     Y A HNL+KAHA +WH Y+  FR  Q G +S++L A 
Sbjct: 690 ----------------PYTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQAD 733

Query: 228 WLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLP 287
           W+EPA P S  D+E A+R + F +   A+PIF  GDYP V++     ++Q+  +    LP
Sbjct: 734 WIEPACPFSQKDKEVAERVLEFDIGWLAEPIFGSGDYPWVMRDW---LNQRNNF---LLP 787

Query: 288 EFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKN-VDWI 346
            FTE+EKK+I+GT DF A+ +YTT L+     K+  +      E++   D +W N    +
Sbjct: 788 YFTEDEKKLIQGTFDFLALSHYTTILV--DSEKEDPIKYNDYLEVQEMTDITWLNSPSQV 845

Query: 347 YVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQL 406
            VVPWG+ K+L ++K  Y +  +YI  NG      A  DD  R  Y +    E  KA  L
Sbjct: 846 AVVPWGLRKVLNWLKFKYGDLPMYIISNGIDDGLHAE-DDQLRVYYMQNYINEALKAHIL 904

Query: 407 DKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNG 464
           D +NL  Y A+S      +N   + RFGL+       A    P  S K Y KII +NG
Sbjct: 905 DGINLCGYFAYS------FNDRTAPRFGLYRY----AADQFEPKASMKHYRKIIDSNG 952


>gi|28376633 klotho beta [Homo sapiens]
          Length = 1044

 Score =  320 bits (821), Expect = 1e-87
 Identities = 179/464 (38%), Positives = 253/464 (54%), Gaps = 39/464 (8%)

Query: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFK-NQTGDVACGSYTLWEE 61
           FP  F W   T A QVEG W  DGKGP +WD F H   + V   N + D    SY   E+
Sbjct: 81  FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSSTNGSSD----SYIFLEK 136

Query: 62  DLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHF 121
           DL  +  +G++ Y+FS+SW RL PDG     N KG+ YY+ ++D L+   + PIVTLYH+
Sbjct: 137 DLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHW 196

Query: 122 DLPQTLEDQ-GGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
           DLP  L+++ GGW ++ II+ F+ YA +CF  FGDRVK WITI+   +++   Y  GM  
Sbjct: 197 DLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHA 256

Query: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQ 240
           PG        Y   HNLIKAH++ WH+Y++ FR  QKG +S++L + W+EP    +  D 
Sbjct: 257 PGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSHWIEPNRSENTMDI 316

Query: 241 EAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGT 300
              ++++   L  FA PI  DGDYPE ++ ++ S+          LP F+E EK  ++GT
Sbjct: 317 FKCQQSMVSVLGWFANPIHGDGDYPEGMRKKLFSV----------LPIFSEAEKHEMRGT 366

Query: 301 ADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYI 360
           ADFFA  +          N   ++G               +NV         + + L +I
Sbjct: 367 ADFFAFSFGPNNFKPL--NTMAKMG---------------QNVS------LNLREALNWI 403

Query: 361 KDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLL 420
           K  YNNP I I ENG+        +DT      +    ++ +AI+LD++ +  Y AWSLL
Sbjct: 404 KLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLL 463

Query: 421 DNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNG 464
           D FEW   Y+ R GLF+VDF    + R P +SA  Y +IIR NG
Sbjct: 464 DGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENG 507



 Score =  265 bits (676), Expect = 9e-71
 Identities = 164/473 (34%), Positives = 247/473 (52%), Gaps = 38/473 (8%)

Query: 3   FPAGFGWAAATAAYQVEGGWDADGKGP---CVWDTFTHQGGERV--FKNQTGDVACGSYT 57
           FP  F W    +  + E    +         VW+   ++   RV   + +T    C  + 
Sbjct: 521 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHRVEGVRLKTRPAQCTDFV 580

Query: 58  LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVT 117
             ++ L+ + ++ +THYRF+L W+ +LP G    +N++ + YY  ++ + LK G++ +VT
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640

Query: 118 LY-----HFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVM 172
           LY     H  LP+ L    GWL+ +  E+F  YA  CF   GD VK WITINE N LS +
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDI 700

Query: 173 SYDLGMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPA 232
                         G   Y AAHNL+ AHA +W  YD  FR  Q+G VSLSL A W EPA
Sbjct: 701 ----------YNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHADWAEPA 750

Query: 233 DPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEE 292
           +P + S   AA+R + F +  FA+P+F  GDYP  ++  IAS   ++G  SS LP  TE 
Sbjct: 751 NPYADSHWRAAERFLQFEIAWFAEPLFKTGDYPAAMREYIAS-KHRRGLSSSALPRLTEA 809

Query: 293 EKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPD-PSWKNVDWIYVVPW 351
           E++++KGT DF A+ ++TTR + +++          D +I+F  D     +   + V+PW
Sbjct: 810 ERRLLKGTVDFCALNHFTTRFVMHEQLAGSRYD--SDRDIQFLQDITRLSSPTRLAVIPW 867

Query: 352 GVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNL 411
           GV KLL++++  Y +  IYIT +G    D A  DD  R  Y  +  QE+ KA  +DKV +
Sbjct: 868 GVRKLLRWVRRNYGDMDIYITASGI--DDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRI 925

Query: 412 QVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNG 464
           + Y A+ L +     +    RFG F  DF+         +S + Y K+I + G
Sbjct: 926 KGYYAFKLAE-----EKSKPRFGFFTSDFK-------AKSSIQFYNKVISSRG 966


>gi|190360571 cytosolic beta-glucosidase isoform b [Homo sapiens]
          Length = 162

 Score =  212 bits (540), Expect = 5e-55
 Identities = 96/97 (98%), Positives = 96/97 (98%)

Query: 1  MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
          MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE
Sbjct: 1  MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60

Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGI 97
          EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQK I
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97



 Score =  146 bits (368), Expect = 5e-35
 Identities = 68/68 (100%), Positives = 68/68 (100%)

Query: 402 KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIR 461
           KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIR
Sbjct: 95  KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIR 154

Query: 462 NNGLEAHL 469
           NNGLEAHL
Sbjct: 155 NNGLEAHL 162


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,560,310
Number of Sequences: 37866
Number of extensions: 906127
Number of successful extensions: 1689
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1640
Number of HSP's gapped (non-prelim): 13
length of query: 469
length of database: 18,247,518
effective HSP length: 106
effective length of query: 363
effective length of database: 14,233,722
effective search space: 5166841086
effective search space used: 5166841086
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.