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Search of human proteins with 4826726
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4826726 fibroblast growth factor 19 precursor [Homo sapiens]
(216 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4826726 fibroblast growth factor 19 precursor [Homo sapiens] 446 e-126
gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens] 99 3e-21
gi|10190674 fibroblast growth factor 23 precursor [Homo sapiens] 75 3e-14
gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens] 62 5e-10
gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens] 61 8e-10
gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens] 60 1e-09
gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens] 60 2e-09
gi|153285461 fibroblast growth factor 2 [Homo sapiens] 56 2e-08
gi|222144221 fibroblast growth factor 1 (acidic) isoform 1 propr... 55 3e-08
gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprot... 55 3e-08
gi|222144273 fibroblast growth factor 1 (acidic) isoform 1 propr... 55 3e-08
gi|222144271 fibroblast growth factor 1 (acidic) isoform 1 propr... 55 3e-08
gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens] 55 5e-08
gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens] 55 5e-08
gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo... 54 1e-07
gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens] 50 1e-06
gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens] 50 1e-06
gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens] 50 1e-06
gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens] 50 1e-06
gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens] 50 1e-06
gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens] 50 1e-06
gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens] 50 2e-06
gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens] 50 2e-06
gi|9789947 fibroblast growth factor 20 [Homo sapiens] 48 6e-06
gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens] 47 1e-05
gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens] 47 1e-05
gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens] 47 1e-05
gi|4503691 fibroblast growth factor 16 [Homo sapiens] 46 3e-05
gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens] 43 2e-04
gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens] 38 0.006
>gi|4826726 fibroblast growth factor 19 precursor [Homo sapiens]
Length = 216
Score = 446 bits (1146), Expect = e-126
Identities = 216/216 (100%), Positives = 216/216 (100%)
Query: 1 MRSGCVVVHVWILAGLWLAVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFL 60
MRSGCVVVHVWILAGLWLAVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFL
Sbjct: 1 MRSGCVVVHVWILAGLWLAVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFL 60
Query: 61 RIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDC 120
RIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDC
Sbjct: 61 RIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDC 120
Query: 121 AFEEEIRPDGYNVYRSEKHRLPVSLSSAKQRQLYKNRGFLPLSHFLPMLPMVPEEPEDLR 180
AFEEEIRPDGYNVYRSEKHRLPVSLSSAKQRQLYKNRGFLPLSHFLPMLPMVPEEPEDLR
Sbjct: 121 AFEEEIRPDGYNVYRSEKHRLPVSLSSAKQRQLYKNRGFLPLSHFLPMLPMVPEEPEDLR 180
Query: 181 GHLESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK 216
GHLESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK
Sbjct: 181 GHLESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK 216
>gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens]
Length = 209
Score = 99.0 bits (245), Expect = 3e-21
Identities = 78/210 (37%), Positives = 104/210 (49%), Gaps = 22/210 (10%)
Query: 10 VWILAGLWL-AVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFLRIRADGVV 68
V +LAGL L A P+ D+ P + +G +R R+LYT + L IR DG V
Sbjct: 15 VSVLAGLLLGACQAHPIP--DSSPLLQFG--GQVRQRYLYTDDAQQ-TEAHLEIREDGTV 69
Query: 69 DCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRP 128
A QS SLL++KA+ + I GV + R+LC DG + G L + E C+F E +
Sbjct: 70 GGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLE 129
Query: 129 DGYNVYRSEKHRLPVSLSSAKQ-RQLYKNRG---FLPLSHFLPMLPMVPEEPEDLRGHLE 184
DGYNVY+SE H LP+ L K + RG FLPL P LP EP +
Sbjct: 130 DGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALP----EPPGI----- 180
Query: 185 SDMFSSPLETDSMDPFGLVTGLEAVRSPSF 214
+ P + S DP +V G RSPS+
Sbjct: 181 --LAPQPPDVGSSDPLSMV-GPSQGRSPSY 207
>gi|10190674 fibroblast growth factor 23 precursor [Homo sapiens]
Length = 251
Score = 75.5 bits (184), Expect = 3e-14
Identities = 55/174 (31%), Positives = 82/174 (47%), Gaps = 16/174 (9%)
Query: 8 VHVWILAGLWLAVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFLRIRADGV 67
+ +W+ A + A+ +A P + WG I HLYT+ +S L+I +G
Sbjct: 6 LRLWVCALCSVCSMSVLRAYPNASPLLGSSWGGLI---HLYTATAR--NSYHLQIHKNGH 60
Query: 68 VDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIR 127
VD A Q+ +S L I++ V I GV S RYLCM G + G + E+C F+ +
Sbjct: 61 VDGAPHQTIYSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGSHYFDPENCRFQHQTL 120
Query: 128 PDGYNVYRSEKHRLPVSLSSAKQ-----------RQLYKNRGFLPLSHFLPMLP 170
+GY+VY S ++ VSL AK+ Q R +PL HF +P
Sbjct: 121 ENGYDVYHSPQYHFLVSLGRAKRAFLPGMNPPPYSQFLSRRNEIPLIHFNTPIP 174
>gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]
Length = 208
Score = 61.6 bits (148), Expect = 5e-10
Identities = 49/152 (32%), Positives = 80/152 (52%), Gaps = 17/152 (11%)
Query: 28 SDAGPHV---HYGWGDPIRLRHLYTSGPHGLSSCFLRIRADGVVDCARGQSA-HSLLEIK 83
S AG HV ++ GD +R R L++ + FL+I +G V + ++ +S+LEI
Sbjct: 61 SSAGRHVRSYNHLQGD-VRWRKLFS-----FTKYFLKIEKNGKVSGTKKENCPYSILEIT 114
Query: 84 AVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRS-----EK 138
+V + VA+K ++S YL M GK+ G +++ DC +E I +GYN Y S
Sbjct: 115 SVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFN-NDCKLKERIEENGYNTYASFNWQHNG 173
Query: 139 HRLPVSLS-SAKQRQLYKNRGFLPLSHFLPML 169
++ V+L+ R+ K R +HFLPM+
Sbjct: 174 RQMYVALNGKGAPRRGQKTRRKNTSAHFLPMV 205
>gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]
Length = 239
Score = 60.8 bits (146), Expect = 8e-10
Identities = 45/121 (37%), Positives = 63/121 (52%), Gaps = 8/121 (6%)
Query: 31 GPHVHYGWGDPIRLRHLYTSGPHGLSSCFLRIRADGVVDCARGQSAHSLLEIKAVALRTV 90
G + H G G P R R LY + + L++ G V+ + SA+S+LEI AV + V
Sbjct: 34 GVYEHLG-GAP-RRRKLYCATKY-----HLQLHPSGRVNGSLENSAYSILEITAVEVGIV 86
Query: 91 AIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSEKHRLPVSLSSAKQ 150
AI+G+ S RYL M G++ YS E C F E I GYN Y S +R S A++
Sbjct: 87 AIRGLFSGRYLAMNKRGRLYASEHYSAE-CEFVERIHELGYNTYASRLYRTVSSTPGARR 145
Query: 151 R 151
+
Sbjct: 146 Q 146
>gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens]
Length = 170
Score = 60.1 bits (144), Expect = 1e-09
Identities = 52/166 (31%), Positives = 80/166 (48%), Gaps = 15/166 (9%)
Query: 11 WILAGLWLAVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFLRIRADGVVDC 70
W+L AG P A GP + +R R L++S + FLR+ G V
Sbjct: 11 WLLLARAPDAAGTPSA--SRGPRSYPHLEGDVRWRRLFSS-----THFFLRVDPGGRVQG 63
Query: 71 ARGQSAH-SLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPD 129
R + S+LEI++V + V IK V S Y+ M G++ G Y+ DC F E I +
Sbjct: 64 TRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTV-DCRFRERIEEN 122
Query: 130 GYNVYRSEKHR---LPVSLSSAKQ---RQLYKNRGFLPLSHFLPML 169
G+N Y S++ R P+ L+ ++ R + R + +HFLP+L
Sbjct: 123 GHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVL 168
>gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]
Length = 206
Score = 59.7 bits (143), Expect = 2e-09
Identities = 50/158 (31%), Positives = 81/158 (51%), Gaps = 10/158 (6%)
Query: 18 LAVAGRPLAFSDAGPHVHYGWGDPI----RLRHLYTSGPHGLSSCFLRIRADGVVDCARG 73
L++A P+A V G GD + RLR LY + G L+ DG + A
Sbjct: 53 LSLARLPVAAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFH---LQALPDGRIGGAHA 109
Query: 74 QSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNV 133
+ SLLE+ V V+I GV S ++ M + GK+ G +++E C F+E + P+ YN
Sbjct: 110 DTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDE-CTFKEILLPNNYNA 168
Query: 134 YRSEKH-RLPVSLS-SAKQRQLYKNRGFLPLSHFLPML 169
Y S K+ + ++LS + K ++ + + ++HFLP L
Sbjct: 169 YESYKYPGMFIALSKNGKTKKGNRVSPTMKVTHFLPRL 206
>gi|153285461 fibroblast growth factor 2 [Homo sapiens]
Length = 288
Score = 56.2 bits (134), Expect = 2e-08
Identities = 43/114 (37%), Positives = 59/114 (51%), Gaps = 10/114 (8%)
Query: 59 FLRIRADGVVDCARGQS-AHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSE 117
FLRI DG VD R +S H L+++A V+IKGV + RYL M DG++ ++
Sbjct: 173 FLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTD 232
Query: 118 EDCAFEEEIRPDGYNVYRSEKH-RLPVSLSSAKQRQLYKNRG-------FLPLS 163
E C F E + + YN YRS K+ V+L Q +L G FLP+S
Sbjct: 233 E-CFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMS 285
>gi|222144221 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 55.5 bits (132), Expect = 3e-08
Identities = 33/82 (40%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 59 FLRIRADGVVDCARGQS-AHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSE 117
FLRI DG VD R +S H L++ A ++ V IK + +YL M DG + G Q
Sbjct: 37 FLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS-QTPN 95
Query: 118 EDCAFEEEIRPDGYNVYRSEKH 139
E+C F E + + YN Y S+KH
Sbjct: 96 EECLFLERLEENHYNTYISKKH 117
>gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprotein
[Homo sapiens]
Length = 155
Score = 55.5 bits (132), Expect = 3e-08
Identities = 33/82 (40%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 59 FLRIRADGVVDCARGQS-AHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSE 117
FLRI DG VD R +S H L++ A ++ V IK + +YL M DG + G Q
Sbjct: 37 FLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS-QTPN 95
Query: 118 EDCAFEEEIRPDGYNVYRSEKH 139
E+C F E + + YN Y S+KH
Sbjct: 96 EECLFLERLEENHYNTYISKKH 117
>gi|222144273 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 55.5 bits (132), Expect = 3e-08
Identities = 33/82 (40%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 59 FLRIRADGVVDCARGQS-AHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSE 117
FLRI DG VD R +S H L++ A ++ V IK + +YL M DG + G Q
Sbjct: 37 FLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS-QTPN 95
Query: 118 EDCAFEEEIRPDGYNVYRSEKH 139
E+C F E + + YN Y S+KH
Sbjct: 96 EECLFLERLEENHYNTYISKKH 117
>gi|222144271 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 55.5 bits (132), Expect = 3e-08
Identities = 33/82 (40%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 59 FLRIRADGVVDCARGQS-AHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSE 117
FLRI DG VD R +S H L++ A ++ V IK + +YL M DG + G Q
Sbjct: 37 FLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS-QTPN 95
Query: 118 EDCAFEEEIRPDGYNVYRSEKH 139
E+C F E + + YN Y S+KH
Sbjct: 96 EECLFLERLEENHYNTYISKKH 117
>gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]
Length = 194
Score = 55.1 bits (131), Expect = 5e-08
Identities = 46/140 (32%), Positives = 69/140 (49%), Gaps = 13/140 (9%)
Query: 36 YGWGDPIRLRHLYTSGPHGLSSCFLRIRADGVVDCARG-QSAHSLLEIKAVALRTVAIKG 94
Y G IR+R L+ + +LRI G V + ++ ++++EI+ VA+ VAIKG
Sbjct: 58 YMEGGDIRVRRLFCR-----TQWYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGIVAIKG 112
Query: 95 VHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSEK--HRLPVSLSSAKQRQ 152
V S YL M +GK+ + EDC F+E I + YN Y S K H + Q+
Sbjct: 113 VESEFYLAMNKEGKLYAKKE-CNEDCNFKELILENHYNTYASAKWTHNGGEMFVALNQKG 171
Query: 153 L----YKNRGFLPLSHFLPM 168
+ K + +HFLPM
Sbjct: 172 IPVRGKKTKKEQKTAHFLPM 191
>gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]
Length = 208
Score = 55.1 bits (131), Expect = 5e-08
Identities = 37/129 (28%), Positives = 66/129 (51%), Gaps = 6/129 (4%)
Query: 43 RLRHLYTSGPHGLSSCFLRIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLC 102
R R LY + G L++ DG + ++ +SLLEI V V++ GV S ++
Sbjct: 84 RQRRLYCNVGIGFH---LQVLPDGRISGTHEENPYSLLEISTVERGVVSLFGVRSALFVA 140
Query: 103 MGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSEKHR-LPVSLSS-AKQRQLYKNRGFL 160
M + G++ + EE C F E + P+ YN Y S+ ++ ++LS + ++ K +
Sbjct: 141 MNSKGRLYATPSFQEE-CKFRETLLPNNYNAYESDLYQGTYIALSKYGRVKRGSKVSPIM 199
Query: 161 PLSHFLPML 169
++HFLP +
Sbjct: 200 TVTHFLPRI 208
>gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo
sapiens]
Length = 268
Score = 53.5 bits (127), Expect = 1e-07
Identities = 30/81 (37%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Query: 60 LRIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEED 119
L+I DG V+ + + S+LEI AV+ V I+GV S ++L M GK+ +++ +D
Sbjct: 101 LQIYPDGKVNGSHEANMLSVLEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASAKFT-DD 159
Query: 120 CAFEEEIRPDGYNVYRSEKHR 140
C F E + + YN Y S HR
Sbjct: 160 CKFRERFQENSYNTYASAIHR 180
>gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 50.1 bits (118), Expect = 1e-06
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 11/156 (7%)
Query: 60 LRIRADGVVDCARGQ-SAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEE 118
L+++ADG +D + + S ++L + V LR VAI+GV + YL M ++G + ++ E
Sbjct: 62 LQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTPE 121
Query: 119 DCAFEEEIRPDGYNVYRSEKHRLPVS-----LSSAKQRQLYKN---RGFLPLSHFLPM-L 169
C F+E + + Y Y S +R S L K+ ++ K + P +HFLP L
Sbjct: 122 -CKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPL 180
Query: 170 PMVPEEPEDLRGHLESDMFSSPLETDSMDPFGLVTG 205
+ + L E S T S G++ G
Sbjct: 181 KVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNG 216
>gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 50.1 bits (118), Expect = 1e-06
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 11/156 (7%)
Query: 60 LRIRADGVVDCARGQ-SAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEE 118
L+++ADG +D + + S ++L + V LR VAI+GV + YL M ++G + ++ E
Sbjct: 62 LQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTPE 121
Query: 119 DCAFEEEIRPDGYNVYRSEKHRLPVS-----LSSAKQRQLYKN---RGFLPLSHFLPM-L 169
C F+E + + Y Y S +R S L K+ ++ K + P +HFLP L
Sbjct: 122 -CKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPL 180
Query: 170 PMVPEEPEDLRGHLESDMFSSPLETDSMDPFGLVTG 205
+ + L E S T S G++ G
Sbjct: 181 KVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNG 216
>gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]
Length = 255
Score = 50.1 bits (118), Expect = 1e-06
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 11/156 (7%)
Query: 60 LRIRADGVVDCARGQ-SAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEE 118
L+++ADG +D + + S ++L + V LR VAI+GV + YL M ++G + ++ E
Sbjct: 91 LQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTPE 150
Query: 119 DCAFEEEIRPDGYNVYRSEKHRLPVS-----LSSAKQRQLYKN---RGFLPLSHFLPM-L 169
C F+E + + Y Y S +R S L K+ ++ K + P +HFLP L
Sbjct: 151 -CKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPL 209
Query: 170 PMVPEEPEDLRGHLESDMFSSPLETDSMDPFGLVTG 205
+ + L E S T S G++ G
Sbjct: 210 KVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNG 245
>gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]
Length = 199
Score = 50.1 bits (118), Expect = 1e-06
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 11/156 (7%)
Query: 60 LRIRADGVVDCARGQ-SAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEE 118
L+++ADG +D + + S ++L + V LR VAI+GV + YL M ++G + ++ E
Sbjct: 35 LQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTPE 94
Query: 119 DCAFEEEIRPDGYNVYRSEKHRLPVS-----LSSAKQRQLYKN---RGFLPLSHFLPM-L 169
C F+E + + Y Y S +R S L K+ ++ K + P +HFLP L
Sbjct: 95 -CKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPL 153
Query: 170 PMVPEEPEDLRGHLESDMFSSPLETDSMDPFGLVTG 205
+ + L E S T S G++ G
Sbjct: 154 KVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNG 189
>gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]
Length = 245
Score = 50.1 bits (118), Expect = 1e-06
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 11/156 (7%)
Query: 60 LRIRADGVVDCARGQ-SAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEE 118
L+++ADG +D + + S ++L + V LR VAI+GV + YL M ++G + ++ E
Sbjct: 81 LQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTPE 140
Query: 119 DCAFEEEIRPDGYNVYRSEKHRLPVS-----LSSAKQRQLYKN---RGFLPLSHFLPM-L 169
C F+E + + Y Y S +R S L K+ ++ K + P +HFLP L
Sbjct: 141 -CKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPL 199
Query: 170 PMVPEEPEDLRGHLESDMFSSPLETDSMDPFGLVTG 205
+ + L E S T S G++ G
Sbjct: 200 KVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNG 235
>gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]
Length = 192
Score = 50.1 bits (118), Expect = 1e-06
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 11/156 (7%)
Query: 60 LRIRADGVVDCARGQ-SAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEE 118
L+++ADG +D + + S ++L + V LR VAI+GV + YL M ++G + ++ E
Sbjct: 28 LQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTPE 87
Query: 119 DCAFEEEIRPDGYNVYRSEKHRLPVS-----LSSAKQRQLYKN---RGFLPLSHFLPM-L 169
C F+E + + Y Y S +R S L K+ ++ K + P +HFLP L
Sbjct: 88 -CKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPL 146
Query: 170 PMVPEEPEDLRGHLESDMFSSPLETDSMDPFGLVTG 205
+ + L E S T S G++ G
Sbjct: 147 KVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNG 182
>gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens]
Length = 181
Score = 49.7 bits (117), Expect = 2e-06
Identities = 35/118 (29%), Positives = 61/118 (51%), Gaps = 10/118 (8%)
Query: 59 FLRIRADGVVDCARGQSA-HSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSE 117
FL++ DG +D + +++ ++L + V LR VAI+GV + Y+ M +G + ++
Sbjct: 22 FLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTP 81
Query: 118 EDCAFEEEIRPDGYNVYRSEKHRLPVS-----LSSAKQRQLYKN---RGFLPLSHFLP 167
E C F+E + + Y +Y S +R S L K+ Q+ K + P SHF+P
Sbjct: 82 E-CKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVP 138
>gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens]
Length = 243
Score = 49.7 bits (117), Expect = 2e-06
Identities = 35/118 (29%), Positives = 61/118 (51%), Gaps = 10/118 (8%)
Query: 59 FLRIRADGVVDCARGQSA-HSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSE 117
FL++ DG +D + +++ ++L + V LR VAI+GV + Y+ M +G + ++
Sbjct: 84 FLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTP 143
Query: 118 EDCAFEEEIRPDGYNVYRSEKHRLPVS-----LSSAKQRQLYKN---RGFLPLSHFLP 167
E C F+E + + Y +Y S +R S L K+ Q+ K + P SHF+P
Sbjct: 144 E-CKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVP 200
>gi|9789947 fibroblast growth factor 20 [Homo sapiens]
Length = 211
Score = 48.1 bits (113), Expect = 6e-06
Identities = 49/148 (33%), Positives = 71/148 (47%), Gaps = 18/148 (12%)
Query: 42 IRLRHLYT-SGPHGLSSCFLRIRADGVVDCAR-GQSAHSLLEIKAVALRTVAIKGVHSVR 99
+R R LY +G H L+I DG V R S +LE +VA+ V+I+GV S
Sbjct: 64 LRRRQLYCRTGFH------LQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGL 117
Query: 100 YLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSE--KH-----RLPVSLS-SAKQR 151
YL M G++ G + + E C F E+ + YN Y S KH R V+L+ R
Sbjct: 118 YLGMNDKGELYGSEKLTSE-CIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPR 176
Query: 152 QLYKNRGFLPLSHFLPMLPMVPEEPEDL 179
+++ +HFLP P+ PE +L
Sbjct: 177 DGARSKRHQKFTHFLPR-PVDPERVPEL 203
>gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]
Length = 208
Score = 47.0 bits (110), Expect = 1e-05
Identities = 45/148 (30%), Positives = 72/148 (48%), Gaps = 18/148 (12%)
Query: 42 IRLRHLYT-SGPHGLSSCFLRIRADGVVDCAR-GQSAHSLLEIKAVALRTVAIKGVHSVR 99
+R R LY +G H L I +G + R S +LE ++A+ V+I+GV S
Sbjct: 61 LRRRQLYCRTGFH------LEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGL 114
Query: 100 YLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSE--KH-----RLPVSLS-SAKQR 151
YL M G++ G + ++E C F E+ + YN Y S KH R V+L+ R
Sbjct: 115 YLGMNEKGELYGSEKLTQE-CVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPR 173
Query: 152 QLYKNRGFLPLSHFLPMLPMVPEEPEDL 179
+ + + +HFLP P+ P++ +L
Sbjct: 174 EGTRTKRHQKFTHFLPR-PVDPDKVPEL 200
>gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]
Length = 252
Score = 47.0 bits (110), Expect = 1e-05
Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 10/118 (8%)
Query: 59 FLRIRADGVVDCARGQSAHS-LLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSE 117
+L++ DG +D + S +S L + V LR VAI+GV + Y+ M +G + ++
Sbjct: 87 YLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTP 146
Query: 118 EDCAFEEEIRPDGYNVYRSEKHRLPVS-----LSSAKQRQLYKN---RGFLPLSHFLP 167
E C F+E + + Y +Y S +R S L K+ Q K + P +HFLP
Sbjct: 147 E-CKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLP 203
>gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens]
Length = 247
Score = 47.0 bits (110), Expect = 1e-05
Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 10/118 (8%)
Query: 59 FLRIRADGVVDCARGQSAHS-LLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSE 117
+L++ DG +D + S +S L + V LR VAI+GV + Y+ M +G + ++
Sbjct: 82 YLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTP 141
Query: 118 EDCAFEEEIRPDGYNVYRSEKHRLPVS-----LSSAKQRQLYKN---RGFLPLSHFLP 167
E C F+E + + Y +Y S +R S L K+ Q K + P +HFLP
Sbjct: 142 E-CKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLP 198
>gi|4503691 fibroblast growth factor 16 [Homo sapiens]
Length = 207
Score = 45.8 bits (107), Expect = 3e-05
Identities = 44/157 (28%), Positives = 68/157 (43%), Gaps = 22/157 (14%)
Query: 42 IRLRHLYT-SGPHGLSSCFLRIRADGVVDCAR-GQSAHSLLEIKAVALRTVAIKGVHSVR 99
+R R LY +G H L I +G V R S +LE ++A+ ++I+GV S
Sbjct: 60 LRRRQLYCRTGFH------LEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGL 113
Query: 100 YLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYR--------SEKHRLPVSLSSAKQR 151
YL M G++ G + + E C F E+ + YN Y SE+ R
Sbjct: 114 YLGMNERGELYGSKKLTRE-CVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPR 172
Query: 152 QLYKNRGFLPLSHFLPMLPMVPEEPEDLRGHLESDMF 188
+ Y+ + +HFLP P +P L + D+F
Sbjct: 173 EGYRTKRHQKFTHFLPR----PVDPSKLPS-MSRDLF 204
>gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens]
Length = 216
Score = 42.7 bits (99), Expect = 2e-04
Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 90 VAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSEKHR--LPVSLSS 147
V IKG S +Y+CM GK+ G +DC F E + + Y +++ +H
Sbjct: 97 VRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQ 156
Query: 148 AKQRQLYKNRGFLPLSHFLPML 169
+ RQ ++R +HF+ L
Sbjct: 157 GRPRQASRSRQNQREAHFIKRL 178
>gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens]
Length = 207
Score = 38.1 bits (87), Expect = 0.006
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 15/104 (14%)
Query: 42 IRLRHLY--TSGPHGLSSCFLRIRADGVVDCARGQS----AHSLLEIKAVALRTVAIKGV 95
+RL LY TSG H I+ G ARG+ A L+E + V IKG
Sbjct: 52 LRLYQLYSRTSGKH--------IQVLGRRISARGEDGDKYAQLLVETDTFGSQ-VRIKGK 102
Query: 96 HSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSEKH 139
+ YLCM GK+ G + ++C F E++ + Y S K+
Sbjct: 103 ETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKY 146
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,124,945
Number of Sequences: 37866
Number of extensions: 431082
Number of successful extensions: 860
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 796
Number of HSP's gapped (non-prelim): 55
length of query: 216
length of database: 18,247,518
effective HSP length: 98
effective length of query: 118
effective length of database: 14,536,650
effective search space: 1715324700
effective search space used: 1715324700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.