Guide to the Human Genome
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Search of human proteins with 4758768

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758768 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex,
10, 42kDa precursor [Homo sapiens]
         (355 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758768 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1...   727   0.0  
gi|239748049 PREDICTED: similar to NADH dehydrogenase [ubiquinon...   220   1e-57
gi|18426967 deoxyguanosine kinase isoform a precursor [Homo sapi...    41   0.001
gi|18426971 deoxyguanosine kinase isoform b precursor [Homo sapi...    36   0.060
gi|8923421 seryl-tRNA synthetase 2 isoform b precursor [Homo sap...    31   1.9  
gi|27894378 chloride intracellular channel 6 [Homo sapiens]            29   5.6  
gi|48255924 NADH-ubiquinone oxidoreductase flavoprotein 3 isofor...    29   7.3  
gi|54607077 ankyrin repeat domain 57 [Homo sapiens]                    28   9.6  

>gi|4758768 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10,
           42kDa precursor [Homo sapiens]
          Length = 355

 Score =  727 bits (1876), Expect = 0.0
 Identities = 355/355 (100%), Positives = 355/355 (100%)

Query: 1   MALRLLKLAATSASARVVAAGAQRVRGIHSSVQCKLRYGMWHFLLGDKASKRLTERSRVI 60
           MALRLLKLAATSASARVVAAGAQRVRGIHSSVQCKLRYGMWHFLLGDKASKRLTERSRVI
Sbjct: 1   MALRLLKLAATSASARVVAAGAQRVRGIHSSVQCKLRYGMWHFLLGDKASKRLTERSRVI 60

Query: 61  TVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGKPLATDYNGNCSLEKFYDD 120
           TVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGKPLATDYNGNCSLEKFYDD
Sbjct: 61  TVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGKPLATDYNGNCSLEKFYDD 120

Query: 121 PRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLERSIFSDFVFLEAMYNQGFIR 180
           PRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLERSIFSDFVFLEAMYNQGFIR
Sbjct: 121 PRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLERSIFSDFVFLEAMYNQGFIR 180

Query: 181 KQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENA 240
           KQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENA
Sbjct: 181 KQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENA 240

Query: 241 YKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQD 300
           YKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQD
Sbjct: 241 YKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQD 300

Query: 301 KFEVLNYTSIPIFLPEVTIGAHQTDRVLHQFRELPGRKYSPGYNTEVGDKWIWLK 355
           KFEVLNYTSIPIFLPEVTIGAHQTDRVLHQFRELPGRKYSPGYNTEVGDKWIWLK
Sbjct: 301 KFEVLNYTSIPIFLPEVTIGAHQTDRVLHQFRELPGRKYSPGYNTEVGDKWIWLK 355


>gi|239748049 PREDICTED: similar to NADH dehydrogenase [ubiquinone]
           1 alpha subcomplex subunit 10, mitochondrial [Homo
           sapiens]
          Length = 128

 Score =  220 bits (561), Expect = 1e-57
 Identities = 104/105 (99%), Positives = 105/105 (100%)

Query: 251 EKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQDKFEVLNYTSI 310
           +KCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQDKFEVLNYTSI
Sbjct: 24  KKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQDKFEVLNYTSI 83

Query: 311 PIFLPEVTIGAHQTDRVLHQFRELPGRKYSPGYNTEVGDKWIWLK 355
           PIFLPEVTIGAHQTDRVLHQFRELPGRKYSPGYNTEVGDKWIWLK
Sbjct: 84  PIFLPEVTIGAHQTDRVLHQFRELPGRKYSPGYNTEVGDKWIWLK 128


>gi|18426967 deoxyguanosine kinase isoform a precursor [Homo
           sapiens]
          Length = 277

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 47/198 (23%), Positives = 84/198 (42%), Gaps = 22/198 (11%)

Query: 58  RVITVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTT-------GDGKPLATDYNG 110
           R ++++GNI  GK    K +      K +PE  +      T       G  K       G
Sbjct: 39  RRLSIEGNIAVGKSTFVKLLT-----KTYPEWHVATEPVATWQNIQAAGTQKACTAQSLG 93

Query: 111 NCSLEKFYDDPRSNDGNSYRLQSWLYSSRL-LQYSDALEHLLTTGQGV-VLERSIFSD-F 167
           N  L+  Y +P      SY  Q++ + SRL +Q     E LL   + V + ERS++SD +
Sbjct: 94  NL-LDMMYREPAR---WSYTFQTFSFLSRLKVQLEPFPEKLLQARKPVQIFERSVYSDRY 149

Query: 168 VFLEAMYNQGFIRKQCVDHYNEVKSVTICDY---LPPHLVIYIDVPVPEVQRRIQKKGDP 224
           +F + ++  G +       Y +  S  + ++   +  H  IY+        +R+ ++   
Sbjct: 150 IFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLHGFIYLQASPQVCLKRLYQRARE 209

Query: 225 HEMKITSAYLQDIENAYK 242
            E  I  AYL+ +   ++
Sbjct: 210 EEKGIELAYLEQLHGQHE 227


>gi|18426971 deoxyguanosine kinase isoform b precursor [Homo
           sapiens]
          Length = 189

 Score = 35.8 bits (81), Expect = 0.060
 Identities = 39/141 (27%), Positives = 61/141 (43%), Gaps = 18/141 (12%)

Query: 58  RVITVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTT-------GDGKPLATDYNG 110
           R ++++GNI  GK    K +      K +PE  +      T       G  K       G
Sbjct: 39  RRLSIEGNIAVGKSTFVKLLT-----KTYPEWHVATEPVATWQNIQAAGTQKACTAQSLG 93

Query: 111 NCSLEKFYDDPRSNDGNSYRLQSWLYSSRL-LQYSDALEHLLTTGQGV-VLERSIFSDFV 168
           N  L+  Y +P      SY  Q++ + SRL +Q     E LL   + V + ERS++SD +
Sbjct: 94  NL-LDMMYREPARW---SYTFQTFSFLSRLKVQLEPFPEKLLQARKPVQIFERSVYSDRL 149

Query: 169 FLEAMYNQGFIRKQCVDHYNE 189
             EA+ N   +     D ++E
Sbjct: 150 HFEALMNIPVLVLDVNDDFSE 170


>gi|8923421 seryl-tRNA synthetase 2 isoform b precursor [Homo
           sapiens]
          Length = 518

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 1/88 (1%)

Query: 264 QDSKKVVEDIEYLKFD-KGPWLKQDNRTLYHLRLLVQDKFEVLNYTSIPIFLPEVTIGAH 322
           QDS +V +D +Y     +G  ++++   LY     ++++F +          P+V +G  
Sbjct: 124 QDSGEVQQDPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPDVPVGDE 183

Query: 323 QTDRVLHQFRELPGRKYSPGYNTEVGDK 350
              RVLH   + P   + P  + E+G+K
Sbjct: 184 SQARVLHMVGDKPVFSFQPRGHLEIGEK 211


>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
          Length = 686

 Score = 29.3 bits (64), Expect = 5.6
 Identities = 12/39 (30%), Positives = 22/39 (56%)

Query: 60  ITVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTT 98
           +T DG + T   K+ + + EKL    +P+ G  +P+S +
Sbjct: 512 MTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNS 550


>gi|48255924 NADH-ubiquinone oxidoreductase flavoprotein 3 isoform a
           precursor [Homo sapiens]
          Length = 473

 Score = 28.9 bits (63), Expect = 7.3
 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 6/62 (9%)

Query: 206 YIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENAYKKTFLPEMSEKCEVLQYSAREAQD 265
           ++D+  PE   + +KKG P +        +  ENA  KT +P      E L+ S +E Q 
Sbjct: 215 HVDITDPEKPHQPKKKGSPAKPS------EGRENARPKTTMPRSQVDEEFLKQSLKEKQL 268

Query: 266 SK 267
            K
Sbjct: 269 QK 270


>gi|54607077 ankyrin repeat domain 57 [Homo sapiens]
          Length = 525

 Score = 28.5 bits (62), Expect = 9.6
 Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 5/81 (6%)

Query: 94  PDSTTGDGKPLATDYNGNCSLEKFYDDPRSNDGNSYRLQ----SWLYSSRLLQYSDALEH 149
           P S++G G+      + + S+     +  S+ G S  L     +W+ S+   ++ D+LE 
Sbjct: 227 PGSSSGGGRGRGGGDSDSASVASSSAEEESSGGGSVTLDPLEHAWMLSASDGKW-DSLEG 285

Query: 150 LLTTGQGVVLERSIFSDFVFL 170
           LLT   G++++R   + F  L
Sbjct: 286 LLTCEPGLLVKRDFITGFTCL 306


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,572,604
Number of Sequences: 37866
Number of extensions: 602587
Number of successful extensions: 1207
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1203
Number of HSP's gapped (non-prelim): 8
length of query: 355
length of database: 18,247,518
effective HSP length: 103
effective length of query: 252
effective length of database: 14,347,320
effective search space: 3615524640
effective search space used: 3615524640
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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