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Search of human proteins with 4758326
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758326 coagulation factor II (thrombin) receptor-like 2
precursor [Homo sapiens]
(374 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758326 coagulation factor II (thrombin) receptor-like 2 prec... 774 0.0
gi|34577052 coagulation factor II (thrombin) receptor-like 1 pre... 220 1e-57
gi|89353783 coagulation factor II (thrombin) receptor-like 3 pre... 204 1e-52
gi|166362740 coagulation factor II receptor precursor [Homo sapi... 194 1e-49
gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo sap... 176 2e-44
gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens] 152 6e-37
gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] 151 1e-36
gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] 151 1e-36
gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] 151 1e-36
gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] 151 1e-36
gi|4505557 purinergic receptor P2Y1 [Homo sapiens] 148 7e-36
gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens] 142 5e-34
gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens] 141 8e-34
gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens] 140 1e-33
gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sa... 139 5e-33
gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sa... 139 5e-33
gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sap... 139 5e-33
gi|224586796 G protein-coupled receptor 87 [Homo sapiens] 137 2e-32
gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens] 135 8e-32
gi|28872720 purinergic receptor P2Y2 [Homo sapiens] 135 8e-32
gi|28872745 purinergic receptor P2Y2 [Homo sapiens] 135 8e-32
gi|28872743 purinergic receptor P2Y2 [Homo sapiens] 135 8e-32
gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo ... 133 2e-31
gi|4504681 interleukin 8 receptor alpha [Homo sapiens] 131 9e-31
gi|40217829 G protein-coupled receptor 68 [Homo sapiens] 131 9e-31
gi|148225857 G protein-coupled receptor 34 [Homo sapiens] 131 1e-30
gi|4885319 G protein-coupled receptor 34 [Homo sapiens] 131 1e-30
gi|4504683 interleukin 8 receptor beta [Homo sapiens] 128 9e-30
gi|14043066 angiotensin II receptor, type 1 [Homo sapiens] 127 2e-29
gi|14043064 angiotensin II receptor, type 1 [Homo sapiens] 127 2e-29
>gi|4758326 coagulation factor II (thrombin) receptor-like 2
precursor [Homo sapiens]
Length = 374
Score = 774 bits (1998), Expect = 0.0
Identities = 374/374 (100%), Positives = 374/374 (100%)
Query: 1 MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWT 60
MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWT
Sbjct: 1 MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWT 60
Query: 61 GATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLF 120
GATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLF
Sbjct: 61 GATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLF 120
Query: 121 FRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCS 180
FRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCS
Sbjct: 121 FRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCS 180
Query: 181 ILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQP 240
ILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQP
Sbjct: 181 ILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQP 240
Query: 241 DITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYV 300
DITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYV
Sbjct: 241 DITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYV 300
Query: 301 KASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFL 360
KASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFL
Sbjct: 301 KASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFL 360
Query: 361 MSKTRNHSTAYLTK 374
MSKTRNHSTAYLTK
Sbjct: 361 MSKTRNHSTAYLTK 374
>gi|34577052 coagulation factor II (thrombin) receptor-like 1
precursor [Homo sapiens]
Length = 397
Score = 220 bits (561), Expect = 1e-57
Identities = 120/322 (37%), Positives = 177/322 (54%), Gaps = 32/322 (9%)
Query: 61 GATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLF 120
G T+ E SAS LT L+T +P +Y +VFVVG+P+N + LW+
Sbjct: 52 GVTVETVFSVDEFSAS----------VLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFL 101
Query: 121 FRTRSICTTVFY-TNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYC 179
FRT+ V Y NLA+AD L + P KIAYH++GNNW++GE LC FYGNMYC
Sbjct: 102 FRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYC 161
Query: 180 SILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQ 239
SIL + C+S+ RY IV+P + K A+ +W + L +P +++KQ ++
Sbjct: 162 SILFMTCLSVQRYWVIVNPMGH-SRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPA 220
Query: 240 PDITTCHDVHNTCESSSPFQLY------YFISLAFFGFLIPFVLIIYCYAAIIRTLNA-- 291
+ITTCHDV P QL YF+SLA FL P L Y +IR L +
Sbjct: 221 LNITTCHDV-------LPEQLLVGDMFNYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSA 273
Query: 292 ----YDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLG 347
+ + +K + +L ++ ICF PSN++L++H+ +Y +Y++ALCL
Sbjct: 274 MDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALCLS 333
Query: 348 SLNSCLDPFLYFLMSKT-RNHS 368
+LNSC+DPF+Y+ +S R+H+
Sbjct: 334 TLNSCIDPFVYYFVSHDFRDHA 355
>gi|89353783 coagulation factor II (thrombin) receptor-like 3
precursor [Homo sapiens]
Length = 385
Score = 204 bits (518), Expect = 1e-52
Identities = 108/293 (36%), Positives = 165/293 (56%), Gaps = 2/293 (0%)
Query: 70 CPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTT 129
C +S + L + +++ L + T+L+PA+Y LV VVG+PAN + LW+L + + +T
Sbjct: 54 CANDSDT-LELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLATQAPRLPST 112
Query: 130 VFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISI 189
+ NLA AD L + LP +IAYHL G W FGE CR T YG+MY S+LLLA +S+
Sbjct: 113 MLLMNLAAADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHMYGSVLLLAAVSL 172
Query: 190 NRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVH 249
+RYLA+VHP R L AL C W LP + +Q + L + D CHD
Sbjct: 173 DRYLALVHPLRARALRGRRLALGLCMAAWLMAAALALPLTLQRQTFRLARSDRVLCHDAL 232
Query: 250 NTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYVKASLLILVI 309
+S +Q F LA G +P + ++ CY A + TL A R+ ++ + ++L
Sbjct: 233 PLDAQASHWQ-PAFTCLALLGCFLPLLAMLLCYGATLHTLAASGRRYGHALRLTAVVLAS 291
Query: 310 FTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMS 362
F PSN++L++H+++ + LY Y+ +L L +LNSC+DPF+Y+ +S
Sbjct: 292 AVAFFVPSNLLLLLHYSDPSPSAWGNLYGAYVPSLALSTLNSCVDPFIYYYVS 344
>gi|166362740 coagulation factor II receptor precursor [Homo
sapiens]
Length = 425
Score = 194 bits (492), Expect = 1e-49
Identities = 123/372 (33%), Positives = 191/372 (51%), Gaps = 18/372 (4%)
Query: 3 ALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNS-FEEFPFSALEGWTG 61
A F+ G LL T + TN TL ++F PN +E F + +G
Sbjct: 10 AACFSLCGPLLSARTRARRPESKATN----ATLDPRSFLLRNPNDKYEPFWEDEEKNESG 65
Query: 62 AT----ITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPAN--AVT 115
T +++ P + + GYLTSS T +P++Y VFVV +P N A+
Sbjct: 66 LTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSLPLNIMAIV 125
Query: 116 LWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYG 175
+++L + + V+ +LA AD LF LPFKI+Y+ +G++W FG LCR T FY
Sbjct: 126 VFILKMKVKKPAV-VYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRFVTAAFYC 184
Query: 176 NMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEY 235
NMY SILL+ ISI+R+LA+V+P A TC +WA ++P + +Q
Sbjct: 185 NMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIAGVVPLLLKEQTI 244
Query: 236 YLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLN----A 291
+ +ITTCHDV N + YYF + + F +P ++ CY +IIR L+ A
Sbjct: 245 QVPGLNITTCHDVLNETLLEG-YYAYYFSAFSAVFFFVPLIISTVCYVSIIRCLSSSAVA 303
Query: 292 YDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANY-YYNNTDGLYFIYLIALCLGSLN 350
+ + S + IF ICF P+N++LI H++ + + T+ YF YL+ +C+ S++
Sbjct: 304 NRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTSTTEAAYFAYLLCVCVSSIS 363
Query: 351 SCLDPFLYFLMS 362
C+DP +Y+ S
Sbjct: 364 CCIDPLIYYYAS 375
>gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo
sapiens]
Length = 359
Score = 176 bits (447), Expect = 2e-44
Identities = 98/289 (33%), Positives = 150/289 (51%), Gaps = 8/289 (2%)
Query: 82 NATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTTV-FYTNLAIADF 140
NAT+ L + +P +Y LV V +P N +LW+L R +V F NL++ D
Sbjct: 11 NATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDL 70
Query: 141 LFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFT 200
+ LPF+I YH N ++WVFG +LC TV FY NMY SIL + CIS+ R+L +++P +
Sbjct: 71 MLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLS 130
Query: 201 YRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHN-TCESSSPFQ 259
+ + YA+ C W + + P Y + I TC DV T S
Sbjct: 131 SKRWRRRRYAVAACAGTWLLLLTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMW 190
Query: 260 LYYFISLAFFGFLIPFVLIIYCYAA----IIRTLNAYD-HRWLWYVKASLLILVIFTICF 314
+ ++ FLIPFV+ + CY A ++RT A+ + V + ++L+ F CF
Sbjct: 191 AVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCF 250
Query: 315 APSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSK 363
AP+N +L+ H + + Y +Y + LCL LN+CLDPF+Y+ S+
Sbjct: 251 APNNFVLLAHIVSRLFYG-KSYYHVYKLTLCLSCLNNCLDPFVYYFASR 298
>gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens]
Length = 361
Score = 152 bits (383), Expect = 6e-37
Identities = 95/297 (31%), Positives = 152/297 (51%), Gaps = 27/297 (9%)
Query: 87 YLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSI-CTTVFYTNLAIADFLFCVT 145
Y S + ++P Y LVF++G+ N + L ++ + I TT++ TNL I+D LF
Sbjct: 24 YAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSTNLVISDILFTTA 83
Query: 146 LPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLP 205
LP +IAY+ G +W G+ LCR T ++FY N Y + + C+SI+R++A+VHP Y +
Sbjct: 84 LPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIK 143
Query: 206 KHTYALVTCGLVWATVFLYMLPFFI---LKQEYYLVQPDITTCHDVHNTCESSSPFQLYY 262
+ +A C VW VF LP I KQE + TC + N E+ S +
Sbjct: 144 RIEHAKGVCIFVWILVFAQTLPLLINPMSKQE-----AERITCMEYPNFEETKS--LPWI 196
Query: 263 FISLAFFGFLIPFVLIIYCYAAIIRTL------NAYDHRWLWYVKA---SLLILVIFTIC 313
+ F G+++P ++I+ CY+ I L N + KA +LI+V+F +C
Sbjct: 197 LLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLC 256
Query: 314 FAPSNIILIIH------HANYYYNNTDGLYFIYL-IALCLGSLNSCLDPFLYFLMSK 363
F P ++ +I H +N+ + + I L +CL + N C+DPF+YF K
Sbjct: 257 FTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACK 313
>gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 151 bits (381), Expect = 1e-36
Identities = 100/293 (34%), Positives = 147/293 (50%), Gaps = 22/293 (7%)
Query: 92 LSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICT--TVFYTNLAIADFLFCVTLPFK 149
L L + YLL F++ + N + LW LF R T VF +LA+AD + LP +
Sbjct: 29 LENMLFASFYLLDFILALVGNTLALW-LFIRDHKSGTPANVFLMHLAVADLSCVLVLPTR 87
Query: 150 IAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTY 209
+ YH +GN+W FGE+ CR T +FY NMY SI L CIS +R+LAIVHP L + Y
Sbjct: 88 LVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLY 147
Query: 210 ALVTCGLVWATVFLYMLPFFILKQEYYLVQPDIT-TCHDVHNTCESSSPFQLYYFISLAF 268
A + C +W V + M P + Q VQ + T C ++ E +S L +SLA
Sbjct: 148 AHLACAFLWVVVAVAMAPLLVSPQ---TVQTNHTVVCLQLYR--EKASHHAL---VSLA- 198
Query: 269 FGFLIPFVLIIYCYAAIIRT----LNAYDHRWLWYVKASLLILVIFTICFAPSNI---IL 321
F PF+ + CY IIR+ L V+ ++L IF +CF P ++ +
Sbjct: 199 VAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVY 258
Query: 322 IIHHANYYYNNTDG--LYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYL 372
++H+ ++ + L I CL SLN LDP +YF +++ H+ L
Sbjct: 259 VLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNL 311
>gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 151 bits (381), Expect = 1e-36
Identities = 100/293 (34%), Positives = 147/293 (50%), Gaps = 22/293 (7%)
Query: 92 LSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICT--TVFYTNLAIADFLFCVTLPFK 149
L L + YLL F++ + N + LW LF R T VF +LA+AD + LP +
Sbjct: 29 LENMLFASFYLLDFILALVGNTLALW-LFIRDHKSGTPANVFLMHLAVADLSCVLVLPTR 87
Query: 150 IAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTY 209
+ YH +GN+W FGE+ CR T +FY NMY SI L CIS +R+LAIVHP L + Y
Sbjct: 88 LVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLY 147
Query: 210 ALVTCGLVWATVFLYMLPFFILKQEYYLVQPDIT-TCHDVHNTCESSSPFQLYYFISLAF 268
A + C +W V + M P + Q VQ + T C ++ E +S L +SLA
Sbjct: 148 AHLACAFLWVVVAVAMAPLLVSPQ---TVQTNHTVVCLQLYR--EKASHHAL---VSLA- 198
Query: 269 FGFLIPFVLIIYCYAAIIRT----LNAYDHRWLWYVKASLLILVIFTICFAPSNI---IL 321
F PF+ + CY IIR+ L V+ ++L IF +CF P ++ +
Sbjct: 199 VAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVY 258
Query: 322 IIHHANYYYNNTDG--LYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYL 372
++H+ ++ + L I CL SLN LDP +YF +++ H+ L
Sbjct: 259 VLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNL 311
>gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 151 bits (381), Expect = 1e-36
Identities = 100/293 (34%), Positives = 147/293 (50%), Gaps = 22/293 (7%)
Query: 92 LSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICT--TVFYTNLAIADFLFCVTLPFK 149
L L + YLL F++ + N + LW LF R T VF +LA+AD + LP +
Sbjct: 57 LENMLFASFYLLDFILALVGNTLALW-LFIRDHKSGTPANVFLMHLAVADLSCVLVLPTR 115
Query: 150 IAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTY 209
+ YH +GN+W FGE+ CR T +FY NMY SI L CIS +R+LAIVHP L + Y
Sbjct: 116 LVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLY 175
Query: 210 ALVTCGLVWATVFLYMLPFFILKQEYYLVQPDIT-TCHDVHNTCESSSPFQLYYFISLAF 268
A + C +W V + M P + Q VQ + T C ++ E +S L +SLA
Sbjct: 176 AHLACAFLWVVVAVAMAPLLVSPQ---TVQTNHTVVCLQLYR--EKASHHAL---VSLA- 226
Query: 269 FGFLIPFVLIIYCYAAIIRT----LNAYDHRWLWYVKASLLILVIFTICFAPSNI---IL 321
F PF+ + CY IIR+ L V+ ++L IF +CF P ++ +
Sbjct: 227 VAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVY 286
Query: 322 IIHHANYYYNNTDG--LYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYL 372
++H+ ++ + L I CL SLN LDP +YF +++ H+ L
Sbjct: 287 VLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNL 339
>gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 151 bits (381), Expect = 1e-36
Identities = 100/293 (34%), Positives = 147/293 (50%), Gaps = 22/293 (7%)
Query: 92 LSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICT--TVFYTNLAIADFLFCVTLPFK 149
L L + YLL F++ + N + LW LF R T VF +LA+AD + LP +
Sbjct: 57 LENMLFASFYLLDFILALVGNTLALW-LFIRDHKSGTPANVFLMHLAVADLSCVLVLPTR 115
Query: 150 IAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTY 209
+ YH +GN+W FGE+ CR T +FY NMY SI L CIS +R+LAIVHP L + Y
Sbjct: 116 LVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLY 175
Query: 210 ALVTCGLVWATVFLYMLPFFILKQEYYLVQPDIT-TCHDVHNTCESSSPFQLYYFISLAF 268
A + C +W V + M P + Q VQ + T C ++ E +S L +SLA
Sbjct: 176 AHLACAFLWVVVAVAMAPLLVSPQ---TVQTNHTVVCLQLYR--EKASHHAL---VSLA- 226
Query: 269 FGFLIPFVLIIYCYAAIIRT----LNAYDHRWLWYVKASLLILVIFTICFAPSNI---IL 321
F PF+ + CY IIR+ L V+ ++L IF +CF P ++ +
Sbjct: 227 VAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVY 286
Query: 322 IIHHANYYYNNTDG--LYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYL 372
++H+ ++ + L I CL SLN LDP +YF +++ H+ L
Sbjct: 287 VLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNL 339
>gi|4505557 purinergic receptor P2Y1 [Homo sapiens]
Length = 373
Score = 148 bits (374), Expect = 7e-36
Identities = 92/282 (32%), Positives = 142/282 (50%), Gaps = 19/282 (6%)
Query: 97 IPAIYLLVFVVGVPANAVTLWMLFFRTRSIC-TTVFYTNLAIADFLFCVTLPFKIAYHLN 155
+PA+Y+LVF++G N+V +WM F + +V+ NLA+ADFL+ +TLP I Y+ N
Sbjct: 54 LPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFN 113
Query: 156 GNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCG 215
+W+FG+ +C+ IF+ N+Y SIL L CIS +RY +V+P G K A+
Sbjct: 114 KTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISV 173
Query: 216 LVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPF 275
LVW V + + P I TC+D T + Y + F +P
Sbjct: 174 LVWLIVVVAISPILFYSGTGVRKNKTI-TCYD--TTSDEYLRSYFIYSMCTTVAMFCVPL 230
Query: 276 VLIIYCYAAIIRTL------NAYDHRWLWYVKASLLILVIFTICFAPSNIILIIH-HANY 328
VLI+ CY I+R L N+ R Y+ +++L +F + + P +++ ++ A
Sbjct: 231 VLILGCYGLIVRALIYKDLDNSPLRRKSIYL--VIIVLTVFAVSYIPFHVMKTMNLRARL 288
Query: 329 YYNN------TDGLYFIYLIALCLGSLNSCLDPFLYFLMSKT 364
+ D +Y Y + L SLNSC+DP LYFL T
Sbjct: 289 DFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDT 330
>gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens]
Length = 370
Score = 142 bits (358), Expect = 5e-34
Identities = 89/287 (31%), Positives = 144/287 (50%), Gaps = 28/287 (9%)
Query: 91 SLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSIC-TTVFYTNLAIADFLFCVTLPFK 149
S L A+Y +VF++G+ N+V+L++ FR + T +F TNLA++D LF TLPFK
Sbjct: 36 SFKYNLNGAVYSVVFILGLITNSVSLFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFK 95
Query: 150 IAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTY 209
I Y+ N +W FG+ LC+ + F N+Y S+L L CIS++R+LAIV+PF R +
Sbjct: 96 IFYNFN-RHWPFGDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRN 154
Query: 210 ALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLY--YFISLA 267
+ + C VW V + + T ++ TC +++ Y +
Sbjct: 155 SAIVCAGVWILVLSGGISASLF---------STTNVNNATTTCFEGFSKRVWKTYLSKIT 205
Query: 268 FF----GFLIPFVLIIYCYAAIIR------TLNAYDHRWLWYVKASLLILVIFTICFAPS 317
F GF+IP +L + C + ++R TL+ +K + + +F +CF P
Sbjct: 206 IFIEVVGFIIPLILNVSCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPY 265
Query: 318 NIILIIHHANYYYNNTDGLY-----FIYLIALCLGSLNSCLDPFLYF 359
N +L ++ T+ +Y I LCL +LN C DPF+Y+
Sbjct: 266 NSVLFLYALVRSQAITNCFLERFAKIMYPITLCLATLNCCFDPFIYY 312
>gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens]
Length = 346
Score = 141 bits (356), Expect = 8e-34
Identities = 92/308 (29%), Positives = 153/308 (49%), Gaps = 23/308 (7%)
Query: 63 TITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFR 122
+I+V P + S+ + +N T+ + + P +YL++F GV N +++++
Sbjct: 11 SISVSEMEPNGTFSNNNSRNCTI----ENFKREFFPIVYLIIFFWGVLGNGLSIYVFLQP 66
Query: 123 -TRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSI 181
+S VF NLAI+D LF TLPF+ Y+L G+NW+FG++ CR + Y NMY SI
Sbjct: 67 YKKSTSVNVFMLNLAISDLLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYVNMYSSI 126
Query: 182 LLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPD 241
L +S+ R+LA+VHPF + A + CG++W L M +L
Sbjct: 127 YFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGIIW---ILIMASSIMLLDSGSEQNGS 183
Query: 242 ITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYD-------- 293
+T+C +++ + Q +I+L G L+PF + CY IIR L +
Sbjct: 184 VTSCLELN--LYKIAKLQTMNYIALV-VGCLLPFFTLSICYLLIIRVLLKVEVPESGLRV 240
Query: 294 -HRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYN-NTDGLYFIYLIALCLGSLNS 351
HR + ++ L+IF +CF P + + +H + D L+ +I L L + N+
Sbjct: 241 SHRKA--LTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLCKDRLHKALVITLALAAANA 298
Query: 352 CLDPFLYF 359
C +P LY+
Sbjct: 299 CFNPLLYY 306
>gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens]
Length = 365
Score = 140 bits (354), Expect = 1e-33
Identities = 91/280 (32%), Positives = 136/280 (48%), Gaps = 23/280 (8%)
Query: 96 LIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYT-NLAIADFLFCVTLPFKIAYHL 154
L+P Y +VFV+G+ NA TLW+ FR R T Y +LA++D L+ ++LP I Y+
Sbjct: 37 LLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYA 96
Query: 155 NGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTC 214
N+W FG +C+ +FY N+YCS+L L CIS++RYL I HP + A + C
Sbjct: 97 AHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLC 156
Query: 215 GLVWATVFLYMLP--FFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFL 272
VW V ++P FF+ + CHD E F Y S A G L
Sbjct: 157 LAVWLVVAGCLVPNLFFVTTSN----KGTTVLCHDTTRPEE----FDHYVHFSSAVMGLL 208
Query: 273 --IPFVLIIYCYAAIIRTL------NAYDHRWLWYVKASLLILVIFTICFAPSNIILIIH 324
+P ++ + CY + R L +A L ++ ++L +F +CF P +I I+
Sbjct: 209 FGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIY 268
Query: 325 HANYYYNN----TDGLYFIYLIALCLGSLNSCLDPFLYFL 360
+ + + +Y + L S NSCLDP LY L
Sbjct: 269 YLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLL 308
>gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 139 bits (349), Expect = 5e-33
Identities = 93/301 (30%), Positives = 151/301 (50%), Gaps = 18/301 (5%)
Query: 82 NATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLF--FRTRSICTTVFYTNLAIAD 139
N++ + S L ++ +VFV+G+ +N V +++ + R+ TT + NLA++D
Sbjct: 5 NSSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNE-TTTYMINLAMSD 63
Query: 140 FLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPF 199
LF TLPF+I Y NW FG++LC+ + ++FY NMY SIL L CIS++R+LAIV+PF
Sbjct: 64 LLFVFTLPFRIFYFTT-RNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPF 122
Query: 200 TYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESS-SPF 258
+ L A + C VW TV P ++ + C + N E++ +
Sbjct: 123 KSKTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFE--NFPEATWKTY 180
Query: 259 QLYYFISLAFFGFLIPFVLIIYCYAAIIR------TLNAYDHRWLWYVKASLLILVIFTI 312
I + GF IP +L + C + +++ TL+ +K + L+IF
Sbjct: 181 LSRIVIFIEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCF 240
Query: 313 CFAPSNIILIIH---HANYYYNNT--DGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNH 367
CF P NI LI++ + N + + +Y I LC+ N C DP +Y+ S T +
Sbjct: 241 CFVPYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQN 300
Query: 368 S 368
S
Sbjct: 301 S 301
>gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 139 bits (349), Expect = 5e-33
Identities = 93/301 (30%), Positives = 151/301 (50%), Gaps = 18/301 (5%)
Query: 82 NATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLF--FRTRSICTTVFYTNLAIAD 139
N++ + S L ++ +VFV+G+ +N V +++ + R+ TT + NLA++D
Sbjct: 5 NSSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNE-TTTYMINLAMSD 63
Query: 140 FLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPF 199
LF TLPF+I Y NW FG++LC+ + ++FY NMY SIL L CIS++R+LAIV+PF
Sbjct: 64 LLFVFTLPFRIFYFTT-RNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPF 122
Query: 200 TYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESS-SPF 258
+ L A + C VW TV P ++ + C + N E++ +
Sbjct: 123 KSKTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFE--NFPEATWKTY 180
Query: 259 QLYYFISLAFFGFLIPFVLIIYCYAAIIR------TLNAYDHRWLWYVKASLLILVIFTI 312
I + GF IP +L + C + +++ TL+ +K + L+IF
Sbjct: 181 LSRIVIFIEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCF 240
Query: 313 CFAPSNIILIIH---HANYYYNNT--DGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNH 367
CF P NI LI++ + N + + +Y I LC+ N C DP +Y+ S T +
Sbjct: 241 CFVPYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQN 300
Query: 368 S 368
S
Sbjct: 301 S 301
>gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 139 bits (349), Expect = 5e-33
Identities = 93/301 (30%), Positives = 151/301 (50%), Gaps = 18/301 (5%)
Query: 82 NATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLF--FRTRSICTTVFYTNLAIAD 139
N++ + S L ++ +VFV+G+ +N V +++ + R+ TT + NLA++D
Sbjct: 5 NSSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNE-TTTYMINLAMSD 63
Query: 140 FLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPF 199
LF TLPF+I Y NW FG++LC+ + ++FY NMY SIL L CIS++R+LAIV+PF
Sbjct: 64 LLFVFTLPFRIFYFTT-RNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPF 122
Query: 200 TYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESS-SPF 258
+ L A + C VW TV P ++ + C + N E++ +
Sbjct: 123 KSKTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFE--NFPEATWKTY 180
Query: 259 QLYYFISLAFFGFLIPFVLIIYCYAAIIR------TLNAYDHRWLWYVKASLLILVIFTI 312
I + GF IP +L + C + +++ TL+ +K + L+IF
Sbjct: 181 LSRIVIFIEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCF 240
Query: 313 CFAPSNIILIIH---HANYYYNNT--DGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNH 367
CF P NI LI++ + N + + +Y I LC+ N C DP +Y+ S T +
Sbjct: 241 CFVPYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQN 300
Query: 368 S 368
S
Sbjct: 301 S 301
>gi|224586796 G protein-coupled receptor 87 [Homo sapiens]
Length = 358
Score = 137 bits (345), Expect = 2e-32
Identities = 89/300 (29%), Positives = 151/300 (50%), Gaps = 27/300 (9%)
Query: 81 KNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYT-NLAIAD 139
KN T L + T ++P +YL++FV + N + +W +FF R+ + +FY N+ +AD
Sbjct: 32 KNTT---LHNEFDTIVLPVLYLIIFVASILLNGLAVW-IFFHIRNKTSFIFYLKNIVVAD 87
Query: 140 FLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPF 199
+ +T PF+I + W F +LCR T+V+FY NMY SI+ L ISI+RYL +V PF
Sbjct: 88 LIMTLTFPFRIVHDAGFGPWYFKFILCRYTSVLFYANMYTSIVFLGLISIDRYLKVVKPF 147
Query: 200 TYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQ 259
+ T+ V VW + + LP IL QP T ++H+ + SP
Sbjct: 148 GDSRMYSITFTKVLSVCVWVIMAVLSLPNIILTNG----QP---TEDNIHDCSKLKSPLG 200
Query: 260 LYYFISLAFFG---FLIPFVLIIYCYAAIIRTLNAYDHRWL-------WYVKASLLILVI 309
+ + ++ + F+ V++I CY AI R ++ +++ + ++ +++ +
Sbjct: 201 VKWHTAVTYVNSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAV 260
Query: 310 FTICFAPSNIILIIHHANYYYNNTDG-----LYFIYLIALCLGSLNSCLDPFLYFLMSKT 364
F CF P ++ I ++ D LY+ I L L + N CLDP +YF M ++
Sbjct: 261 FFTCFLPYHLCRIPFTFSHLDRLLDESAQKILYYCKEITLFLSACNVCLDPIIYFFMCRS 320
>gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens]
Length = 337
Score = 135 bits (339), Expect = 8e-32
Identities = 99/327 (30%), Positives = 155/327 (47%), Gaps = 36/327 (11%)
Query: 73 ESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLF--FRTRSICTTV 130
+ +L V +AT ++ +Y ++ VVG N L++L + +S V
Sbjct: 2 DETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKS-AFQV 60
Query: 131 FYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISIN 190
+ NLA+AD L TLP ++ Y+++ W+FG+ LCR +T Y N+YCSI + +S
Sbjct: 61 YMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFF 120
Query: 191 RYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHN 250
R +AIV P L A C +W V L PF + K + + + T C +
Sbjct: 121 RCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQ--KDEKNNTKCFEPPQ 178
Query: 251 TCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTL-------NAYDHRWLWYVKAS 303
++ + + +++SL F GF+IPFV+II CY II TL N H+ KA
Sbjct: 179 DNQTKNHVLVLHYVSL-FVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHK-----KAI 232
Query: 304 LLILVI---FTICFAPSNIILIIHHANYYYNNTDGLYFI------YLIALCLGSLNSCLD 354
+I+V+ F + F P +I I H ++ +N T + +I L L + N C D
Sbjct: 233 GMIMVVTAAFLVSFMPYHIQRTI-HLHFLHNETKPCDSVLRMQKSVVITLSLAASNCCFD 291
Query: 355 PFLYFL--------MSKTRNHSTAYLT 373
P LYF +S R HS + +T
Sbjct: 292 PLLYFFSGGNFRKRLSTFRKHSLSSVT 318
>gi|28872720 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 135 bits (339), Expect = 8e-32
Identities = 84/280 (30%), Positives = 135/280 (48%), Gaps = 21/280 (7%)
Query: 96 LIPAIYLLVFVVGVPANAVTLWMLFFRTRSI-CTTVFYTNLAIADFLFCVTLPFKIAYHL 154
L+P Y +V V G+ NAV L++ R ++ +T + +LA++D L+ +LP + Y+
Sbjct: 35 LLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYA 94
Query: 155 NGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTC 214
G++W F VLC+ +FY N+YCSIL L CIS++R L ++ P + YA
Sbjct: 95 RGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVA 154
Query: 215 GLVWATVFLYMLP--FFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFL 272
G VW V P +F+ + TCHD + E S F Y + L F
Sbjct: 155 GAVWVLVLACQAPVLYFVTTS----ARGGRVTCHDT-SAPELFSRFVAYSSVMLGLL-FA 208
Query: 273 IPFVLIIYCYAAIIR--------TLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIH 324
+PF +I+ CY + R T V+ ++L +F +CF P ++ ++
Sbjct: 209 VPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLY 268
Query: 325 HA----NYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFL 360
++ + + + + Y + L S NSCLDP LYFL
Sbjct: 269 YSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFL 308
>gi|28872745 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 135 bits (339), Expect = 8e-32
Identities = 84/280 (30%), Positives = 135/280 (48%), Gaps = 21/280 (7%)
Query: 96 LIPAIYLLVFVVGVPANAVTLWMLFFRTRSI-CTTVFYTNLAIADFLFCVTLPFKIAYHL 154
L+P Y +V V G+ NAV L++ R ++ +T + +LA++D L+ +LP + Y+
Sbjct: 35 LLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYA 94
Query: 155 NGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTC 214
G++W F VLC+ +FY N+YCSIL L CIS++R L ++ P + YA
Sbjct: 95 RGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVA 154
Query: 215 GLVWATVFLYMLP--FFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFL 272
G VW V P +F+ + TCHD + E S F Y + L F
Sbjct: 155 GAVWVLVLACQAPVLYFVTTS----ARGGRVTCHDT-SAPELFSRFVAYSSVMLGLL-FA 208
Query: 273 IPFVLIIYCYAAIIR--------TLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIH 324
+PF +I+ CY + R T V+ ++L +F +CF P ++ ++
Sbjct: 209 VPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLY 268
Query: 325 HA----NYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFL 360
++ + + + + Y + L S NSCLDP LYFL
Sbjct: 269 YSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFL 308
>gi|28872743 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 135 bits (339), Expect = 8e-32
Identities = 84/280 (30%), Positives = 135/280 (48%), Gaps = 21/280 (7%)
Query: 96 LIPAIYLLVFVVGVPANAVTLWMLFFRTRSI-CTTVFYTNLAIADFLFCVTLPFKIAYHL 154
L+P Y +V V G+ NAV L++ R ++ +T + +LA++D L+ +LP + Y+
Sbjct: 35 LLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYA 94
Query: 155 NGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTC 214
G++W F VLC+ +FY N+YCSIL L CIS++R L ++ P + YA
Sbjct: 95 RGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVA 154
Query: 215 GLVWATVFLYMLP--FFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFL 272
G VW V P +F+ + TCHD + E S F Y + L F
Sbjct: 155 GAVWVLVLACQAPVLYFVTTS----ARGGRVTCHDT-SAPELFSRFVAYSSVMLGLL-FA 208
Query: 273 IPFVLIIYCYAAIIR--------TLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIH 324
+PF +I+ CY + R T V+ ++L +F +CF P ++ ++
Sbjct: 209 VPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLY 268
Query: 325 HA----NYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFL 360
++ + + + + Y + L S NSCLDP LYFL
Sbjct: 269 YSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFL 308
>gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo
sapiens]
Length = 337
Score = 133 bits (335), Expect = 2e-31
Identities = 84/280 (30%), Positives = 146/280 (52%), Gaps = 13/280 (4%)
Query: 92 LSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSI-CTTVFYTNLAIADFLFCVTLPFKI 150
L +P IY ++F+VG P NAV + F+ R +T+ NLA D L+ +LPF I
Sbjct: 31 LKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLI 90
Query: 151 AYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYA 210
Y+ +G NW+FG+ +C+ F+ N+Y SIL L C SI RY I+HP + + K A
Sbjct: 91 HYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCA 150
Query: 211 LVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFG 270
+V C +VW + ++P L + + + C D+ ++ E ++ +Y + L
Sbjct: 151 VVACAVVWIISLVAVIPMTFLITS--TNRTNRSACLDLTSSDELNT--IKWYNLILTATT 206
Query: 271 FLIPFVLIIYCYAAIIRTL-NAYDHRWLWYVKA---SLLILVIFTICFAPSNIILIIHHA 326
F +P V++ CY II TL + KA ++L+L+ F +CF P +I+ +I
Sbjct: 207 FCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIE 266
Query: 327 NYYYNNT----DGLYFIYLIALCLGSLNSCLDPFLYFLMS 362
+ + + + ++ Y+++ L +LN+ + LY ++S
Sbjct: 267 SRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVS 306
>gi|4504681 interleukin 8 receptor alpha [Homo sapiens]
Length = 350
Score = 131 bits (330), Expect = 9e-31
Identities = 90/290 (31%), Positives = 147/290 (50%), Gaps = 20/290 (6%)
Query: 89 TSSLSTKLIPAIYLLVFVVGVPANA-VTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLP 147
T +L+ ++ Y LVF++ + N+ V L +L+ R T V+ NLA+AD LF +TLP
Sbjct: 34 TETLNKYVVIIAYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLP 93
Query: 148 FKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKH 207
A +NG W+FG LC+ +++ N Y ILLLACIS++RYLAIVH +H
Sbjct: 94 IWAASKVNG--WIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRH 151
Query: 208 TYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLA 267
V G W LPFF+ +Q Y+ C++V ++ +++ I
Sbjct: 152 LVKFVCLG-CWGLSMNLSLPFFLFRQAYH-PNNSSPVCYEVLG--NDTAKWRMVLRILPH 207
Query: 268 FFGFLIPFVLIIYCYAAIIRTL-NAYDHRWLWYVKASLLILVIFTICFAPSNIIL----- 321
FGF++P ++++CY +RTL A+ + ++ +++IF +C+ P N++L
Sbjct: 208 TFGFIVPLFVMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTL 267
Query: 322 ----IIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNH 367
+I + NN I LG L+SCL+P +Y + + H
Sbjct: 268 MRTQVIQESCERRNNIGRALDATEI---LGFLHSCLNPIIYAFIGQNFRH 314
>gi|40217829 G protein-coupled receptor 68 [Homo sapiens]
Length = 375
Score = 131 bits (330), Expect = 9e-31
Identities = 83/288 (28%), Positives = 138/288 (47%), Gaps = 21/288 (7%)
Query: 96 LIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTT-VFYTNLAIADFLFCVTLPFKIAYHL 154
L P +Y+ V VVG PAN ++L+ + + ++ V+ NL +AD + +LPF + Y L
Sbjct: 33 LAPVVYVTVLVVGFPANCLSLYFGYLQIKARNELGVYLCNLTVADLFYICSLPFWLQYVL 92
Query: 155 NGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTC 214
+NW G++ C+ ++ Y N+Y S+ L CIS++RYLA+ HPF + A+
Sbjct: 93 QHDNWSHGDLSCQVCGILLYENIYISVGFLCCISVDRYLAVAHPFRFHQFRTLKAAVGVS 152
Query: 215 GLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLY-----YFISLAFF 269
++WA L + Y+L+ ++ + H C P Q + Y+ L
Sbjct: 153 VVIWAKELLTSI--------YFLMHEEVIEDENQHRVCFEHYPIQAWQRAINYYRFLV-- 202
Query: 270 GFLIPFVLIIYCYAAIIRTL----NAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHH 325
GFL P L++ Y I+R + R + L +VIF CF P +++L++
Sbjct: 203 GFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLACFLPYHVLLLVRS 262
Query: 326 A-NYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYL 372
+ G++ Y +L L S N DP LY +S+T + A L
Sbjct: 263 VWEASCDFAKGVFNAYHFSLLLTSFNCVADPVLYCFVSETTHRDLARL 310
>gi|148225857 G protein-coupled receptor 34 [Homo sapiens]
Length = 381
Score = 131 bits (329), Expect = 1e-30
Identities = 95/307 (30%), Positives = 145/307 (47%), Gaps = 39/307 (12%)
Query: 82 NATMGYLTSSLSTKLIPAI----YLLVFVVGVPANAVTLWM-LFFRTRSICTTVFYTNLA 136
+AT T + KL+ + Y ++F+VG+ N + L++ L + ++ N+A
Sbjct: 38 SATPNVTTCPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVA 97
Query: 137 IADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIV 196
IAD L LPF+I YH+N N W G +LC+ +FY NMY SI+LL IS++RY+ I
Sbjct: 98 IADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKIN 157
Query: 197 HPFTYRGLPKHTYALVTCGLVWATV---FLYMLPFFILKQEYYLVQPDITTC---HDVHN 250
R ++ C +VW FL M+ + K + + T C D HN
Sbjct: 158 RSIQQRKAITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGH-----NSTMCFHYRDKHN 212
Query: 251 TCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHR---------WLWYVK 301
+ ++ FI + F + F+LII Y I + L R + +
Sbjct: 213 AKGEA----IFNFILVVMFWLI--FLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTAR 266
Query: 302 ASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYL------IALCLGSLNSCLDP 355
S ++L+IFTICF P + I+ ++ N Y+ + I L L S NSCLDP
Sbjct: 267 NSFIVLIIFTICFVPYHAFRFIYISSQL--NVSSCYWKEIVHKTNEIMLVLSSFNSCLDP 324
Query: 356 FLYFLMS 362
+YFLMS
Sbjct: 325 VMYFLMS 331
>gi|4885319 G protein-coupled receptor 34 [Homo sapiens]
Length = 381
Score = 131 bits (329), Expect = 1e-30
Identities = 95/307 (30%), Positives = 145/307 (47%), Gaps = 39/307 (12%)
Query: 82 NATMGYLTSSLSTKLIPAI----YLLVFVVGVPANAVTLWM-LFFRTRSICTTVFYTNLA 136
+AT T + KL+ + Y ++F+VG+ N + L++ L + ++ N+A
Sbjct: 38 SATPNVTTCPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVA 97
Query: 137 IADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIV 196
IAD L LPF+I YH+N N W G +LC+ +FY NMY SI+LL IS++RY+ I
Sbjct: 98 IADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKIN 157
Query: 197 HPFTYRGLPKHTYALVTCGLVWATV---FLYMLPFFILKQEYYLVQPDITTC---HDVHN 250
R ++ C +VW FL M+ + K + + T C D HN
Sbjct: 158 RSIQQRKAITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGH-----NSTMCFHYRDKHN 212
Query: 251 TCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHR---------WLWYVK 301
+ ++ FI + F + F+LII Y I + L R + +
Sbjct: 213 AKGEA----IFNFILVVMFWLI--FLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTAR 266
Query: 302 ASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYL------IALCLGSLNSCLDP 355
S ++L+IFTICF P + I+ ++ N Y+ + I L L S NSCLDP
Sbjct: 267 NSFIVLIIFTICFVPYHAFRFIYISSQL--NVSSCYWKEIVHKTNEIMLVLSSFNSCLDP 324
Query: 356 FLYFLMS 362
+YFLMS
Sbjct: 325 VMYFLMS 331
>gi|4504683 interleukin 8 receptor beta [Homo sapiens]
Length = 360
Score = 128 bits (321), Expect = 9e-30
Identities = 88/280 (31%), Positives = 144/280 (51%), Gaps = 22/280 (7%)
Query: 100 IYLLVFVVGVPANA-VTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNN 158
IY LVF++ + N+ V L +L+ R T V+ NLA+AD LF +TLP A +NG
Sbjct: 54 IYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNG-- 111
Query: 159 WVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYAL-VTCGLV 217
W+FG LC+ +++ N Y ILLLACIS++RYLAIVH R L + Y + C +
Sbjct: 112 WIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVH--ATRTLTQKRYLVKFICLSI 169
Query: 218 WATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVL 277
W L LP + ++ Y D+ N +++ +++ I FGF++P ++
Sbjct: 170 WGLSLLLALPVLLFRRTVYSSNVSPACYEDMGN---NTANWRMLLRILPQSFGFIVPLLI 226
Query: 278 IIYCYAAIIRTL-NAYDHRWLWYVKASLLILVIFTICFAPSNIIL---------IIHHAN 327
+++CY +RTL A+ + ++ +++IF +C+ P N++L +I
Sbjct: 227 MLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETC 286
Query: 328 YYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNH 367
N+ D I LG L+SCL+P +Y + + H
Sbjct: 287 ERRNHIDRALDATEI---LGILHSCLNPLIYAFIGQKFRH 323
>gi|14043066 angiotensin II receptor, type 1 [Homo sapiens]
Length = 359
Score = 127 bits (319), Expect = 2e-29
Identities = 86/280 (30%), Positives = 135/280 (48%), Gaps = 14/280 (5%)
Query: 96 LIPAIYLLVFVVGVPANAVTLWMLFFRTR-SICTTVFYTNLAIADFLFCVTLPFKIAYHL 154
+IP +Y ++FVVG+ N++ + +++F + +VF NLA+AD F +TLP Y
Sbjct: 30 MIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTA 89
Query: 155 NGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTC 214
W FG LC+ + N+Y S+ LL C+SI+RYLAIVHP R A VTC
Sbjct: 90 MEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTC 149
Query: 215 GLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIP 274
++W L LP I + +++ +IT C + + S+ P L ++ GFL P
Sbjct: 150 IIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGL--GLTKNILGFLFP 207
Query: 275 FVLIIYCYAAIIRTL-NAYD-----HRWLWYVKASLLILVIFTICFAPSNI-----ILII 323
F++I+ Y I + L AY+ R K + I++ F + P I +LI
Sbjct: 208 FLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQ 267
Query: 324 HHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSK 363
D + I +C+ N+CL+P Y + K
Sbjct: 268 LGIIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGK 307
>gi|14043064 angiotensin II receptor, type 1 [Homo sapiens]
Length = 359
Score = 127 bits (319), Expect = 2e-29
Identities = 86/280 (30%), Positives = 135/280 (48%), Gaps = 14/280 (5%)
Query: 96 LIPAIYLLVFVVGVPANAVTLWMLFFRTR-SICTTVFYTNLAIADFLFCVTLPFKIAYHL 154
+IP +Y ++FVVG+ N++ + +++F + +VF NLA+AD F +TLP Y
Sbjct: 30 MIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTA 89
Query: 155 NGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTC 214
W FG LC+ + N+Y S+ LL C+SI+RYLAIVHP R A VTC
Sbjct: 90 MEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTC 149
Query: 215 GLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIP 274
++W L LP I + +++ +IT C + + S+ P L ++ GFL P
Sbjct: 150 IIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGL--GLTKNILGFLFP 207
Query: 275 FVLIIYCYAAIIRTL-NAYD-----HRWLWYVKASLLILVIFTICFAPSNI-----ILII 323
F++I+ Y I + L AY+ R K + I++ F + P I +LI
Sbjct: 208 FLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQ 267
Query: 324 HHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSK 363
D + I +C+ N+CL+P Y + K
Sbjct: 268 LGIIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGK 307
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.331 0.143 0.464
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,728,104
Number of Sequences: 37866
Number of extensions: 579869
Number of successful extensions: 2805
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 348
Number of HSP's successfully gapped in prelim test: 205
Number of HSP's that attempted gapping in prelim test: 1699
Number of HSP's gapped (non-prelim): 665
length of query: 374
length of database: 18,247,518
effective HSP length: 104
effective length of query: 270
effective length of database: 14,309,454
effective search space: 3863552580
effective search space used: 3863552580
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.