Guide to the Human Genome
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Search of human proteins with 47132595

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47132595 solute carrier family 25 member 3 isoform b
precursor [Homo sapiens]
         (361 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505775 solute carrier family 25 member 3 isoform b precursor...   735   0.0  
gi|47132595 solute carrier family 25 member 3 isoform b precurso...   735   0.0  
gi|6031192 solute carrier family 25 member 3 isoform a precursor...   714   0.0  
gi|186928856 solute carrier family 25, member 19 [Homo sapiens]        89   8e-18
gi|186928860 solute carrier family 25, member 19 [Homo sapiens]        89   8e-18
gi|186928858 solute carrier family 25, member 19 [Homo sapiens]        89   8e-18
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]          83   3e-16
gi|21314739 solute carrier family 25, member 32 [Homo sapiens]         80   3e-15
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ...    78   1e-14
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s...    78   1e-14
gi|13994341 solute carrier family 25 member 2 [Homo sapiens]           76   4e-14
gi|21389315 solute carrier family 25 (mitochondrial carrier; cit...    76   5e-14
gi|239755176 PREDICTED: similar to solute carrier family 25, mem...    76   5e-14
gi|239755174 PREDICTED: similar to solute carrier family 25, mem...    76   5e-14
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ...    76   5e-14
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ...    76   5e-14
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ...    76   5e-14
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ...    76   5e-14
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho...    75   7e-14
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H...    75   7e-14
gi|46094065 mitochondrial carrier family protein [Homo sapiens]        75   1e-13
gi|82775373 solute carrier family 25, member 37 [Homo sapiens]         73   5e-13
gi|48476342 solute carrier family 25, member 23 [Homo sapiens]         72   8e-13
gi|21361114 solute carrier family 25 (mitochondrial carrier; oxo...    71   1e-12
gi|11225256 uncoupling protein 1 [Homo sapiens]                        71   2e-12
gi|60460887 solute carrier family 25, member 42 [Homo sapiens]         70   3e-12
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s...    70   3e-12
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo...    70   3e-12
gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]           69   7e-12
gi|27544933 solute carrier family 25, member 16 [Homo sapiens]         68   1e-11

>gi|4505775 solute carrier family 25 member 3 isoform b precursor
           [Homo sapiens]
          Length = 361

 Score =  735 bits (1897), Expect = 0.0
 Identities = 361/361 (100%), Positives = 361/361 (100%)

Query: 1   MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEYSCEFGS 60
           MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEYSCEFGS
Sbjct: 1   MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEYSCEFGS 60

Query: 61  AKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAK 120
           AKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAK
Sbjct: 61  AKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAK 120

Query: 121 GWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALA 180
           GWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALA
Sbjct: 121 GWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALA 180

Query: 181 PMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT 240
           PMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT
Sbjct: 181 PMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT 240

Query: 241 VEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL 300
           VEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL
Sbjct: 241 VEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL 300

Query: 301 VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLT 360
           VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLT
Sbjct: 301 VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLT 360

Query: 361 Q 361
           Q
Sbjct: 361 Q 361


>gi|47132595 solute carrier family 25 member 3 isoform b precursor
           [Homo sapiens]
          Length = 361

 Score =  735 bits (1897), Expect = 0.0
 Identities = 361/361 (100%), Positives = 361/361 (100%)

Query: 1   MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEYSCEFGS 60
           MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEYSCEFGS
Sbjct: 1   MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEYSCEFGS 60

Query: 61  AKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAK 120
           AKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAK
Sbjct: 61  AKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAK 120

Query: 121 GWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALA 180
           GWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALA
Sbjct: 121 GWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALA 180

Query: 181 PMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT 240
           PMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT
Sbjct: 181 PMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT 240

Query: 241 VEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL 300
           VEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL
Sbjct: 241 VEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL 300

Query: 301 VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLT 360
           VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLT
Sbjct: 301 VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLT 360

Query: 361 Q 361
           Q
Sbjct: 361 Q 361


>gi|6031192 solute carrier family 25 member 3 isoform a precursor
           [Homo sapiens]
          Length = 362

 Score =  714 bits (1842), Expect = 0.0
 Identities = 349/362 (96%), Positives = 357/362 (98%), Gaps = 1/362 (0%)

Query: 1   MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEE-YSCEFG 59
           MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEE YSC++G
Sbjct: 1   MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEQYSCDYG 60

Query: 60  SAKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA 119
           S +++ LCG GG++SCG THTA+VPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA
Sbjct: 61  SGRFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA 120

Query: 120 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 179
           KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL
Sbjct: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 180

Query: 180 APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER 239
           APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER
Sbjct: 181 APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER 240

Query: 240 TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS 299
           TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS
Sbjct: 241 TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS 300

Query: 300 LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL 359
           LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL
Sbjct: 301 LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL 360

Query: 360 TQ 361
           TQ
Sbjct: 361 TQ 362


>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
          Length = 320

 Score = 88.6 bits (218), Expect = 8e-18
 Identities = 78/292 (26%), Positives = 130/292 (44%), Gaps = 38/292 (13%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQV--------DPQ-KYKGIFNGFSVTLKEDGVRGLAKG 121
           G +S  +T   + P D++K R Q+        DP  KY GI       L+E+G     KG
Sbjct: 22  GSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKG 81

Query: 122 WAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRT-SLYLAASASAEFFADIALA 180
             P  +     G  +F  +E+     + ++   + Y  R  S++      A   A + + 
Sbjct: 82  HVPAQILSIGYGAVQFLSFEML----TELVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137

Query: 181 PMEAAKVRI--QTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 238
           P++  + R   Q +P   NTLR A   MY+ EG + FYKG+AP  +   PY  ++F+C+ 
Sbjct: 138 PVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYS 197

Query: 239 RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD-------------- 284
            +++ LYK+ +P   +E  K E L    + G  AGV    +++P D              
Sbjct: 198 -SLKHLYKWAIP---AEGKKNENL-QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHA 252

Query: 285 -SVVSVLNKEKG--SSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYD 333
            +    + + KG    A  VL++ G  G +KGL   ++     T   +F Y+
Sbjct: 253 RAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 33/219 (15%)

Query: 161 TSLYLAASASAEFFADIAL-APMEAAKVRIQTQ---------PGYANTLRDAAPKMYKEE 210
           T   +A + S       AL +P +  K+R Q Q             + +  A+ ++ +EE
Sbjct: 14  TKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEE 73

Query: 211 GLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGY 270
           G  AF+KG  P  +  I Y  ++F  FE   E +++  V   R       +  V FV G 
Sbjct: 74  GPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAR-------EFSVHFVCGG 126

Query: 271 IAGVFCAIVSHPAD------------SVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARI 318
           +A     +  HP D             V + L    G+    + +  G +  +KGL   +
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGT----MYRSEGPQVFYKGLAPTL 182

Query: 319 IMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKL 357
           I I     LQ+  Y S+K  ++   P   +  E+L+  L
Sbjct: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLL 221


>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
          Length = 320

 Score = 88.6 bits (218), Expect = 8e-18
 Identities = 78/292 (26%), Positives = 130/292 (44%), Gaps = 38/292 (13%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQV--------DPQ-KYKGIFNGFSVTLKEDGVRGLAKG 121
           G +S  +T   + P D++K R Q+        DP  KY GI       L+E+G     KG
Sbjct: 22  GSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKG 81

Query: 122 WAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRT-SLYLAASASAEFFADIALA 180
             P  +     G  +F  +E+     + ++   + Y  R  S++      A   A + + 
Sbjct: 82  HVPAQILSIGYGAVQFLSFEML----TELVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137

Query: 181 PMEAAKVRI--QTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 238
           P++  + R   Q +P   NTLR A   MY+ EG + FYKG+AP  +   PY  ++F+C+ 
Sbjct: 138 PVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYS 197

Query: 239 RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD-------------- 284
            +++ LYK+ +P   +E  K E L    + G  AGV    +++P D              
Sbjct: 198 -SLKHLYKWAIP---AEGKKNENL-QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHA 252

Query: 285 -SVVSVLNKEKG--SSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYD 333
            +    + + KG    A  VL++ G  G +KGL   ++     T   +F Y+
Sbjct: 253 RAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 33/219 (15%)

Query: 161 TSLYLAASASAEFFADIAL-APMEAAKVRIQTQ---------PGYANTLRDAAPKMYKEE 210
           T   +A + S       AL +P +  K+R Q Q             + +  A+ ++ +EE
Sbjct: 14  TKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEE 73

Query: 211 GLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGY 270
           G  AF+KG  P  +  I Y  ++F  FE   E +++  V   R       +  V FV G 
Sbjct: 74  GPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAR-------EFSVHFVCGG 126

Query: 271 IAGVFCAIVSHPAD------------SVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARI 318
           +A     +  HP D             V + L    G+    + +  G +  +KGL   +
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGT----MYRSEGPQVFYKGLAPTL 182

Query: 319 IMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKL 357
           I I     LQ+  Y S+K  ++   P   +  E+L+  L
Sbjct: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLL 221


>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
          Length = 320

 Score = 88.6 bits (218), Expect = 8e-18
 Identities = 78/292 (26%), Positives = 130/292 (44%), Gaps = 38/292 (13%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQV--------DPQ-KYKGIFNGFSVTLKEDGVRGLAKG 121
           G +S  +T   + P D++K R Q+        DP  KY GI       L+E+G     KG
Sbjct: 22  GSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKG 81

Query: 122 WAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRT-SLYLAASASAEFFADIALA 180
             P  +     G  +F  +E+     + ++   + Y  R  S++      A   A + + 
Sbjct: 82  HVPAQILSIGYGAVQFLSFEML----TELVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137

Query: 181 PMEAAKVRI--QTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 238
           P++  + R   Q +P   NTLR A   MY+ EG + FYKG+AP  +   PY  ++F+C+ 
Sbjct: 138 PVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYS 197

Query: 239 RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD-------------- 284
            +++ LYK+ +P   +E  K E L    + G  AGV    +++P D              
Sbjct: 198 -SLKHLYKWAIP---AEGKKNENL-QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHA 252

Query: 285 -SVVSVLNKEKG--SSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYD 333
            +    + + KG    A  VL++ G  G +KGL   ++     T   +F Y+
Sbjct: 253 RAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 33/219 (15%)

Query: 161 TSLYLAASASAEFFADIAL-APMEAAKVRIQTQ---------PGYANTLRDAAPKMYKEE 210
           T   +A + S       AL +P +  K+R Q Q             + +  A+ ++ +EE
Sbjct: 14  TKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEE 73

Query: 211 GLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGY 270
           G  AF+KG  P  +  I Y  ++F  FE   E +++  V   R       +  V FV G 
Sbjct: 74  GPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAR-------EFSVHFVCGG 126

Query: 271 IAGVFCAIVSHPAD------------SVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARI 318
           +A     +  HP D             V + L    G+    + +  G +  +KGL   +
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGT----MYRSEGPQVFYKGLAPTL 182

Query: 319 IMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKL 357
           I I     LQ+  Y S+K  ++   P   +  E+L+  L
Sbjct: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLL 221


>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
          Length = 301

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 81/236 (34%), Positives = 107/236 (45%), Gaps = 33/236 (13%)

Query: 68  GFGGVLSCGLTHTAVVPLDLVKCRMQVDPQK-------YKGIFNGFSVTLKEDGVRGLAK 120
           GFGGV    + H    PLD VK R+Q  P         Y G F+ F  TL  +G+ GL +
Sbjct: 18  GFGGVCLVFVGH----PLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYR 73

Query: 121 GWAPTFLGYS-MQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 179
           G A   +G + M  +C FGF  + K L      +  +Y     L+ A   S  F   I +
Sbjct: 74  GMAAPIIGVTPMFAVCFFGF-GLGKKLQQKHPEDVLSY---PQLFAAGMLSGVFTTGI-M 128

Query: 180 APMEAAKVRIQTQPG-----YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKF 234
            P E  K  +Q Q       Y  TL D A K+Y+E G++  YKG     MR +P + M F
Sbjct: 129 TPGERIKCLLQIQASSGESKYTGTL-DCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYF 187

Query: 235 ACFERTVEALYKFVVPKPR--SECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVS 288
                T E L     P+ +  SE S P  L    VAG IAG+F   V+ P D + S
Sbjct: 188 ----MTYEWLKNIFTPEGKRVSELSAPRIL----VAGGIAGIFNWAVAIPPDVLKS 235



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 48/180 (26%), Positives = 80/180 (44%), Gaps = 8/180 (4%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQVDPQ----KYKGIFNGFSVTLKEDGVRGLAKGWAPTF 126
           G+LS   T   + P + +KC +Q+       KY G  +      +E G+RG+ KG   T 
Sbjct: 117 GMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTL 176

Query: 127 LGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAK 186
           +         F  YE  K +++   G+  + L    + +A   +  F   +A+ P +  K
Sbjct: 177 MRDVPASGMYFMTYEWLKNIFTPE-GKRVSELSAPRILVAGGIAGIFNWAVAIPP-DVLK 234

Query: 187 VRIQTQPG--YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEAL 244
            R QT P   Y N  RD   ++ ++EG+ + YKG   + +R  P     F  FE  ++ L
Sbjct: 235 SRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFL 294


>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
          Length = 315

 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 55/202 (27%), Positives = 96/202 (47%), Gaps = 18/202 (8%)

Query: 50  AVEEYSCE-----FGSAKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVD--------P 96
           A++ Y  E       + +Y       G ++  +T+    PL + K R+ +          
Sbjct: 105 AIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITN----PLWVTKTRLMLQYDAVVNSPH 160

Query: 97  QKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENT 156
           ++YKG+F+      K +GVRGL KG+ P   G S  G  +F  YE+ K+ Y+  +     
Sbjct: 161 RQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGTS-HGALQFMAYELLKLKYNQHINRLPE 219

Query: 157 YLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFY 216
               T  Y++ +A ++ FA  A  P +  + R+Q Q  + + + D   K +++EG+  FY
Sbjct: 220 AQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGGFY 279

Query: 217 KGVAPLWMRQIPYTMMKFACFE 238
           KG+AP  +R  P   + F  +E
Sbjct: 280 KGIAPNLIRVTPACCITFVVYE 301



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 71/308 (23%), Positives = 125/308 (40%), Gaps = 30/308 (9%)

Query: 47  AAAAVEEYSCEFGSAKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDP-----QKYKG 101
           +A+    +S  F   +Y  L    GV    L++ A+ PLDLVK R  V        KY G
Sbjct: 7   SASGSSAWSTVFRHVRYENL--IAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNG 64

Query: 102 IFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRT 161
           I +  +   K DG+RGL +G  P   G  +     F FY   K   +    E        
Sbjct: 65  ILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAER----LEA 120

Query: 162 SLYLAASASAEFFADIALAPMEAAKVRIQTQ-PGYANT-------LRDAAPKMYKEEGLK 213
           + YL ++A A         P+   K R+  Q     N+       + D   K+YK EG++
Sbjct: 121 TEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVR 180

Query: 214 AFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAG 273
             YKG  P  +    +  ++F  +E       + +   P ++ S  E + V      ++ 
Sbjct: 181 GLYKGFVP-GLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISV----AALSK 235

Query: 274 VFCAIVSHPADSVVSVLNKEKGSSASLV------LKRLGFKGVWKGLFARIIMIGTLTAL 327
           +F    ++P   V + L  +    + ++       ++ G  G +KG+   +I +     +
Sbjct: 236 IFAVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCI 295

Query: 328 QWFIYDSV 335
            + +Y++V
Sbjct: 296 TFVVYENV 303


>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
           sapiens]
          Length = 477

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 69/279 (24%), Positives = 122/279 (43%), Gaps = 23/279 (8%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLG 128
           G ++  ++ T+  PLD +K  MQV   K     IF GF   +KE G+R L +G     + 
Sbjct: 201 GGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIK 260

Query: 129 YSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVR 188
            + +   KF  YE +K L    L EE   +     +++ S +    A   + PME  K R
Sbjct: 261 IAPETAVKFWAYEQYKKL----LTEEGQKIGTFERFISGSMAGAT-AQTFIYPMEVMKTR 315

Query: 189 IQT-QPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKF 247
           +   + G  + + D A K+ K EGL AFYKG  P  +  IPY  +  A +E     L K 
Sbjct: 316 LAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYE-----LLKS 370

Query: 248 VVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS-------- 299
                 ++ S    ++V    G ++     + S+P   V + +  +     S        
Sbjct: 371 YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGL 430

Query: 300 --LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 336
              ++ + G  G+++G+    + +     + + +Y+++K
Sbjct: 431 FRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMK 469



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 37/184 (20%), Positives = 79/184 (42%), Gaps = 16/184 (8%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQVDPQ-KYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGY 129
           G ++     T + P++++K R+ V    +Y GI++     LK +G+    KG+ P  LG 
Sbjct: 295 GSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGI 354

Query: 130 SMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRI 189
                     YE+ K  + +   +++       + L   A +     +A  P+   + R+
Sbjct: 355 IPYAGIDLAVYELLKSYWLDNFAKDSVNPG-VMVLLGCGALSSTCGQLASYPLALVRTRM 413

Query: 190 QTQPGYANTLRDAAPKM---------YKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT 240
           Q Q      + + +P++           +EG+   Y+G+ P +M+ +P   + +  +E  
Sbjct: 414 QAQ-----AMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENM 468

Query: 241 VEAL 244
            + L
Sbjct: 469 KQTL 472



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 39/190 (20%), Positives = 80/190 (42%), Gaps = 21/190 (11%)

Query: 159 WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLR--DAAPKMYKEEGLKAFY 216
           WR    L A   A   +  + AP++  K+ +Q     ++ +       +M KE G+++ +
Sbjct: 195 WRQ---LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLW 251

Query: 217 KGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFC 276
           +G     ++  P T +KF  +E+     YK ++ +   +    E+    F++G +AG   
Sbjct: 252 RGNGTNVIKIAPETAVKFWAYEQ-----YKKLLTEEGQKIGTFER----FISGSMAGATA 302

Query: 277 AIVSHPADSVVSVLNKEKGSS-------ASLVLKRLGFKGVWKGLFARIIMIGTLTALQW 329
               +P + + + L   K          A  +LK  G    +KG    ++ I     +  
Sbjct: 303 QTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 362

Query: 330 FIYDSVKVYF 339
            +Y+ +K Y+
Sbjct: 363 AVYELLKSYW 372


>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
           sapiens]
          Length = 458

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 69/279 (24%), Positives = 122/279 (43%), Gaps = 23/279 (8%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLG 128
           G ++  ++ T+  PLD +K  MQV   K     IF GF   +KE G+R L +G     + 
Sbjct: 182 GGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIK 241

Query: 129 YSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVR 188
            + +   KF  YE +K L    L EE   +     +++ S +    A   + PME  K R
Sbjct: 242 IAPETAVKFWAYEQYKKL----LTEEGQKIGTFERFISGSMAGAT-AQTFIYPMEVMKTR 296

Query: 189 IQT-QPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKF 247
           +   + G  + + D A K+ K EGL AFYKG  P  +  IPY  +  A +E     L K 
Sbjct: 297 LAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYE-----LLKS 351

Query: 248 VVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS-------- 299
                 ++ S    ++V    G ++     + S+P   V + +  +     S        
Sbjct: 352 YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGL 411

Query: 300 --LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 336
              ++ + G  G+++G+    + +     + + +Y+++K
Sbjct: 412 FRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMK 450



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 37/184 (20%), Positives = 79/184 (42%), Gaps = 16/184 (8%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQVDPQ-KYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGY 129
           G ++     T + P++++K R+ V    +Y GI++     LK +G+    KG+ P  LG 
Sbjct: 276 GSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGI 335

Query: 130 SMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRI 189
                     YE+ K  + +   +++       + L   A +     +A  P+   + R+
Sbjct: 336 IPYAGIDLAVYELLKSYWLDNFAKDSVNPG-VMVLLGCGALSSTCGQLASYPLALVRTRM 394

Query: 190 QTQPGYANTLRDAAPKM---------YKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT 240
           Q Q      + + +P++           +EG+   Y+G+ P +M+ +P   + +  +E  
Sbjct: 395 QAQ-----AMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENM 449

Query: 241 VEAL 244
            + L
Sbjct: 450 KQTL 453



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 39/190 (20%), Positives = 80/190 (42%), Gaps = 21/190 (11%)

Query: 159 WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLR--DAAPKMYKEEGLKAFY 216
           WR    L A   A   +  + AP++  K+ +Q     ++ +       +M KE G+++ +
Sbjct: 176 WRQ---LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLW 232

Query: 217 KGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFC 276
           +G     ++  P T +KF  +E+     YK ++ +   +    E+    F++G +AG   
Sbjct: 233 RGNGTNVIKIAPETAVKFWAYEQ-----YKKLLTEEGQKIGTFER----FISGSMAGATA 283

Query: 277 AIVSHPADSVVSVLNKEKGSS-------ASLVLKRLGFKGVWKGLFARIIMIGTLTALQW 329
               +P + + + L   K          A  +LK  G    +KG    ++ I     +  
Sbjct: 284 QTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 343

Query: 330 FIYDSVKVYF 339
            +Y+ +K Y+
Sbjct: 344 AVYELLKSYW 353


>gi|13994341 solute carrier family 25 member 2 [Homo sapiens]
          Length = 301

 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 69/269 (25%), Positives = 112/269 (41%), Gaps = 27/269 (10%)

Query: 68  GFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFL 127
           G  G  +C LT     P D +K +MQ  P  YKG+ + F  T  + G+RG  KG  P  +
Sbjct: 16  GAAGGTACVLTGQ---PFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGLRGFYKGTGPALM 72

Query: 128 GYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKV 187
            Y  +    F  Y   +     + G +           AA + A  FA +AL P E  K 
Sbjct: 73  AYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALCPTELVKC 132

Query: 188 RIQTQ---------PGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 238
           R+QT              NT+      + K++G   FY G++   ++++P     F  +E
Sbjct: 133 RLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEVPGYFFFFGGYE 192

Query: 239 RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD------SVVSVLNK 292
            +      F   + + E       V   ++G +AG+   +V  P D       V+S+  K
Sbjct: 193 LSRSF---FASGRSKDELGP----VHLMLSGGVAGICLWLVVFPVDCIKSRIQVLSMYGK 245

Query: 293 EKGSSASL--VLKRLGFKGVWKGLFARII 319
           + G   +L  V++  G   ++ GL A +I
Sbjct: 246 QAGFIGTLLSVVRNEGIVALYSGLKATMI 274



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 44/182 (24%), Positives = 70/182 (38%), Gaps = 6/182 (3%)

Query: 160 RTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGV 219
           + ++ L A A+      +   P +  KV++QT P     L D   K Y + GL+ FYKG 
Sbjct: 8   QAAIDLTAGAAGGTACVLTGQPFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGLRGFYKGT 67

Query: 220 APLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIV 279
            P  M  +    + F C+    + + K      +++ S     + T  AG  A  F A+ 
Sbjct: 68  GPALMAYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSD----LQTAAAGSFASAFAALA 123

Query: 280 SHPADSVVSVLNK--EKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 337
             P + V   L    E   S  +         V KG+  +   +G    L   +   V  
Sbjct: 124 LCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEVPG 183

Query: 338 YF 339
           YF
Sbjct: 184 YF 185



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 47/191 (24%), Positives = 76/191 (39%), Gaps = 22/191 (11%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQVD---------PQKYKGIFNGFSVTLKEDGVRGLAKG 121
           G  +      A+ P +LVKCR+Q            + +  I++     LK+DG  G   G
Sbjct: 113 GSFASAFAALALCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHG 172

Query: 122 WAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAP 181
            + T L         FG YE+ +  +++  G     L    L L+    A     + + P
Sbjct: 173 LSSTLLQEVPGYFFFFGGYELSRSFFAS--GRSKDELGPVHLMLSGGV-AGICLWLVVFP 229

Query: 182 MEAAKVRIQT------QPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFA 235
           ++  K RIQ       Q G+  TL        + EG+ A Y G+    +R IP     F 
Sbjct: 230 VDCIKSRIQVLSMYGKQAGFIGTLLSVV----RNEGIVALYSGLKATMIRAIPANGALFV 285

Query: 236 CFERTVEALYK 246
            +E + + + K
Sbjct: 286 AYEYSRKMMMK 296


>gi|21389315 solute carrier family 25 (mitochondrial carrier;
           citrate transporter), member 1 precursor [Homo sapiens]
          Length = 311

 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 82/317 (25%), Positives = 136/317 (42%), Gaps = 41/317 (12%)

Query: 40  PRRPRNLAAAAVEEYSCEFGSAK--YYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVD-- 95
           PR PR LAAAA        G AK  +       G L+ G+      P + VK ++Q+D  
Sbjct: 4   PRAPRALAAAAPAS-----GKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDER 58

Query: 96  --PQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGE 153
             P +Y+GI +    T++  GV GL +G +    G   +   +FG +E      SN + +
Sbjct: 59  SHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFE----FLSNHMRD 114

Query: 154 ENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRI---QTQP-----GYANTLRDAAPK 205
               L  T   L    +    A + + PME  KV+    QT P     G+ + +R+    
Sbjct: 115 AQGRLDSTRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVRE---- 170

Query: 206 MYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVT 265
           + +E+GLK  Y+G+    ++Q     ++F     ++   Y+   P      +KP   ++T
Sbjct: 171 IVREQGLKGTYQGLTATVLKQGSNQAIRFFVM-TSLRNWYRGDNP------NKPMNPLIT 223

Query: 266 FVAGYIAGVFCAIVSHPADSVVSVLN-------KEKGSSASLVLKRLGFKGVWKGLFARI 318
            V G IAG      + P D + + +        +        +LK+ G K  +KG   R+
Sbjct: 224 GVFGAIAGAASVFGNTPLDVIKTRMQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRL 283

Query: 319 IMIGTLTALQWFIYDSV 335
             +    A+ + IYD V
Sbjct: 284 GRVCLDVAIVFVIYDEV 300



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 16/189 (8%)

Query: 66  LCGFGGVLSCGLTHTAVV--PLDLVKCRM---QVDPQ-KYKGIFNGFSVTLKEDGVRGLA 119
           LCG G     G+    VV  P++ +K +    Q  P  KY+G F+G    ++E G++G  
Sbjct: 126 LCGLGA----GVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTY 181

Query: 120 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 179
           +G   T L        +F      +  Y      +      T ++ A + +A  F +   
Sbjct: 182 QGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGN--- 238

Query: 180 APMEAAKVRIQTQPG--YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACF 237
            P++  K R+Q      Y NT  D   ++ K+EGLKAFYKG  P   R      + F  +
Sbjct: 239 TPLDVIKTRMQGLEAHKYRNTW-DCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIY 297

Query: 238 ERTVEALYK 246
           +  V+ L K
Sbjct: 298 DEVVKLLNK 306



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 39/185 (21%), Positives = 79/185 (42%), Gaps = 24/185 (12%)

Query: 181 PMEAAKVRIQ----TQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFAC 236
           P E  K ++Q    + P     + D   +  +  G+   Y+G++ L    IP   ++F  
Sbjct: 45  PTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGM 104

Query: 237 FERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSH-PADSV-VSVLNKEK 294
           FE        F+    R    + +      + G  AGV  A+V   P +++ V  ++ + 
Sbjct: 105 FE--------FLSNHMRDAQGRLDS-TRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQT 155

Query: 295 GSSASL---------VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPP 345
             +            +++  G KG ++GL A ++  G+  A+++F+  S++ ++R   P 
Sbjct: 156 SPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPN 215

Query: 346 PPEMP 350
            P  P
Sbjct: 216 KPMNP 220


>gi|239755176 PREDICTED: similar to solute carrier family 25, member
           25 isoform 2 [Homo sapiens]
          Length = 469

 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 70/274 (25%), Positives = 122/274 (44%), Gaps = 23/274 (8%)

Query: 77  LTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGL 134
           ++ T   PLD +K  MQV   +    GI  GF+  ++E G R L +G     L  + +  
Sbjct: 199 VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 258

Query: 135 CKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQ-TQP 193
            KF  YE  K     ++G +   L R    L A + A   A  ++ PME  K R+   + 
Sbjct: 259 IKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKT 313

Query: 194 GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEA-LYKFVVPKP 252
           G  + + D A ++   EG+ AFYKG  P  +  IPY  +  A +E    A L  + V   
Sbjct: 314 GQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV--- 370

Query: 253 RSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL---VLK 303
               + P   V      ++   G +A    A+V     +  S+    + + +SL   +L+
Sbjct: 371 --NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILR 428

Query: 304 RLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 337
             G  G+++GL    + +    ++ + +Y+++K+
Sbjct: 429 TEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 462


>gi|239755174 PREDICTED: similar to solute carrier family 25, member
           25 isoform 1 [Homo sapiens]
          Length = 503

 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 70/274 (25%), Positives = 122/274 (44%), Gaps = 23/274 (8%)

Query: 77  LTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGL 134
           ++ T   PLD +K  MQV   +    GI  GF+  ++E G R L +G     L  + +  
Sbjct: 233 VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 292

Query: 135 CKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQ-TQP 193
            KF  YE  K     ++G +   L R    L A + A   A  ++ PME  K R+   + 
Sbjct: 293 IKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKT 347

Query: 194 GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEA-LYKFVVPKP 252
           G  + + D A ++   EG+ AFYKG  P  +  IPY  +  A +E    A L  + V   
Sbjct: 348 GQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV--- 404

Query: 253 RSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL---VLK 303
               + P   V      ++   G +A    A+V     +  S+    + + +SL   +L+
Sbjct: 405 --NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILR 462

Query: 304 RLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 337
             G  G+++GL    + +    ++ + +Y+++K+
Sbjct: 463 TEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 496


>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
           sapiens]
          Length = 489

 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 70/274 (25%), Positives = 122/274 (44%), Gaps = 23/274 (8%)

Query: 77  LTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGL 134
           ++ T   PLD +K  MQV   +    GI  GF+  ++E G R L +G     L  + +  
Sbjct: 219 VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 278

Query: 135 CKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQ-TQP 193
            KF  YE  K     ++G +   L R    L A + A   A  ++ PME  K R+   + 
Sbjct: 279 IKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKT 333

Query: 194 GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEA-LYKFVVPKP 252
           G  + + D A ++   EG+ AFYKG  P  +  IPY  +  A +E    A L  + V   
Sbjct: 334 GQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV--- 390

Query: 253 RSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL---VLK 303
               + P   V      ++   G +A    A+V     +  S+    + + +SL   +L+
Sbjct: 391 --NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILR 448

Query: 304 RLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 337
             G  G+++GL    + +    ++ + +Y+++K+
Sbjct: 449 TEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 482


>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
           sapiens]
          Length = 469

 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 70/274 (25%), Positives = 122/274 (44%), Gaps = 23/274 (8%)

Query: 77  LTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGL 134
           ++ T   PLD +K  MQV   +    GI  GF+  ++E G R L +G     L  + +  
Sbjct: 199 VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 258

Query: 135 CKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQ-TQP 193
            KF  YE  K     ++G +   L R    L A + A   A  ++ PME  K R+   + 
Sbjct: 259 IKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKT 313

Query: 194 GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEA-LYKFVVPKP 252
           G  + + D A ++   EG+ AFYKG  P  +  IPY  +  A +E    A L  + V   
Sbjct: 314 GQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV--- 370

Query: 253 RSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL---VLK 303
               + P   V      ++   G +A    A+V     +  S+    + + +SL   +L+
Sbjct: 371 --NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILR 428

Query: 304 RLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 337
             G  G+++GL    + +    ++ + +Y+++K+
Sbjct: 429 TEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 462


>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
           sapiens]
          Length = 366

 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 70/274 (25%), Positives = 122/274 (44%), Gaps = 23/274 (8%)

Query: 77  LTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGL 134
           ++ T   PLD +K  MQV   +    GI  GF+  ++E G R L +G     L  + +  
Sbjct: 96  VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 155

Query: 135 CKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQ-TQP 193
            KF  YE  K     ++G +   L R    L A + A   A  ++ PME  K R+   + 
Sbjct: 156 IKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKT 210

Query: 194 GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEA-LYKFVVPKP 252
           G  + + D A ++   EG+ AFYKG  P  +  IPY  +  A +E    A L  + V   
Sbjct: 211 GQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV--- 267

Query: 253 RSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL---VLK 303
               + P   V      ++   G +A    A+V     +  S+    + + +SL   +L+
Sbjct: 268 --NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILR 325

Query: 304 RLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 337
             G  G+++GL    + +    ++ + +Y+++K+
Sbjct: 326 TEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 359


>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
           sapiens]
          Length = 503

 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 70/274 (25%), Positives = 122/274 (44%), Gaps = 23/274 (8%)

Query: 77  LTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGL 134
           ++ T   PLD +K  MQV   +    GI  GF+  ++E G R L +G     L  + +  
Sbjct: 233 VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 292

Query: 135 CKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQ-TQP 193
            KF  YE  K     ++G +   L R    L A + A   A  ++ PME  K R+   + 
Sbjct: 293 IKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKT 347

Query: 194 GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEA-LYKFVVPKP 252
           G  + + D A ++   EG+ AFYKG  P  +  IPY  +  A +E    A L  + V   
Sbjct: 348 GQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV--- 404

Query: 253 RSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL---VLK 303
               + P   V      ++   G +A    A+V     +  S+    + + +SL   +L+
Sbjct: 405 --NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILR 462

Query: 304 RLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 337
             G  G+++GL    + +    ++ + +Y+++K+
Sbjct: 463 TEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 496


>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
           sapiens]
          Length = 325

 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 67/290 (23%), Positives = 126/290 (43%), Gaps = 36/290 (12%)

Query: 69  FGGVLSCGLTHTAVVPLDLVKCRMQVDPQ---------KYKGIFNGFSVTLKEDGVRGLA 119
           +GG+ S  +      P+DL K R+QV  Q         KY+G+F+      KE+GV  L 
Sbjct: 46  YGGLASI-VAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALY 104

Query: 120 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 179
            G AP  L  +  G  K G Y+  K L+   L E+ T L      + +   +   A+   
Sbjct: 105 SGIAPALLRQASYGTIKIGIYQSLKRLFVERL-EDETLLINMICGVVSGVISSTIAN--- 160

Query: 180 APMEAAKVRIQTQPG-YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 238
            P +  K+R+Q Q   +  ++  +   +Y++EG +  ++GV P   R      ++   ++
Sbjct: 161 -PTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYD 219

Query: 239 RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD----------SVVS 288
            T + L               + ++  FV+ +  G+  A+ S+P D          ++V 
Sbjct: 220 ITKKHLI--------LSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVG 271

Query: 289 VLNKEKGSSASL--VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 336
            ++  KG+   +  + K  GF  ++KG +   + +G    + +  Y+ +K
Sbjct: 272 HVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 45/200 (22%), Positives = 89/200 (44%), Gaps = 30/200 (15%)

Query: 159 WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANT---------LRDAAPKMYKE 209
           W+  +Y      A   A+    P++  K R+Q Q    +          +  A  ++ KE
Sbjct: 41  WKPFVY---GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKE 97

Query: 210 EGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAG 269
           EG+ A Y G+AP  +RQ  Y  +K   ++    +L +  V     E  + E L++  + G
Sbjct: 98  EGVLALYSGIAPALLRQASYGTIKIGIYQ----SLKRLFV-----ERLEDETLLINMICG 148

Query: 270 YIAGVFCAIVSHPADSVVSVLNKEKGS--------SASLVLKRLGFKGVWKGLFARIIMI 321
            ++GV  + +++P D V+ +  + +GS        S   + ++ G +G+W+G+       
Sbjct: 149 VVSGVISSTIANPTD-VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRA 207

Query: 322 GTLTALQWFIYDSVKVYFRL 341
             +  ++  +YD  K +  L
Sbjct: 208 AIVVGVELPVYDITKKHLIL 227



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 13/86 (15%)

Query: 67  CGFGGVLSCGLTHTAVVPLDLVKCRMQVDP------QKYKGIFNGFSVTLKEDGVRGLAK 120
           CG  G L+         P+D+V+ RM            YKG  +G     K +G   L K
Sbjct: 245 CGLAGALASN-------PVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 297

Query: 121 GWAPTFLGYSMQGLCKFGFYEVFKVL 146
           G+ P +L      +  F  YE  K L
Sbjct: 298 GFWPNWLRLGPWNIIFFITYEQLKRL 323


>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
           sapiens]
          Length = 322

 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 67/290 (23%), Positives = 126/290 (43%), Gaps = 36/290 (12%)

Query: 69  FGGVLSCGLTHTAVVPLDLVKCRMQVDPQ---------KYKGIFNGFSVTLKEDGVRGLA 119
           +GG+ S  +      P+DL K R+QV  Q         KY+G+F+      KE+GV  L 
Sbjct: 43  YGGLASI-VAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALY 101

Query: 120 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 179
            G AP  L  +  G  K G Y+  K L+   L E+ T L      + +   +   A+   
Sbjct: 102 SGIAPALLRQASYGTIKIGIYQSLKRLFVERL-EDETLLINMICGVVSGVISSTIAN--- 157

Query: 180 APMEAAKVRIQTQPG-YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 238
            P +  K+R+Q Q   +  ++  +   +Y++EG +  ++GV P   R      ++   ++
Sbjct: 158 -PTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYD 216

Query: 239 RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD----------SVVS 288
            T + L               + ++  FV+ +  G+  A+ S+P D          ++V 
Sbjct: 217 ITKKHLI--------LSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVG 268

Query: 289 VLNKEKGSSASL--VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 336
            ++  KG+   +  + K  GF  ++KG +   + +G    + +  Y+ +K
Sbjct: 269 HVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 318



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 45/200 (22%), Positives = 89/200 (44%), Gaps = 30/200 (15%)

Query: 159 WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANT---------LRDAAPKMYKE 209
           W+  +Y      A   A+    P++  K R+Q Q    +          +  A  ++ KE
Sbjct: 38  WKPFVY---GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKE 94

Query: 210 EGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAG 269
           EG+ A Y G+AP  +RQ  Y  +K   ++    +L +  V     E  + E L++  + G
Sbjct: 95  EGVLALYSGIAPALLRQASYGTIKIGIYQ----SLKRLFV-----ERLEDETLLINMICG 145

Query: 270 YIAGVFCAIVSHPADSVVSVLNKEKGS--------SASLVLKRLGFKGVWKGLFARIIMI 321
            ++GV  + +++P D V+ +  + +GS        S   + ++ G +G+W+G+       
Sbjct: 146 VVSGVISSTIANPTD-VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRA 204

Query: 322 GTLTALQWFIYDSVKVYFRL 341
             +  ++  +YD  K +  L
Sbjct: 205 AIVVGVELPVYDITKKHLIL 224



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 13/86 (15%)

Query: 67  CGFGGVLSCGLTHTAVVPLDLVKCRMQVDP------QKYKGIFNGFSVTLKEDGVRGLAK 120
           CG  G L+         P+D+V+ RM            YKG  +G     K +G   L K
Sbjct: 242 CGLAGALASN-------PVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 294

Query: 121 GWAPTFLGYSMQGLCKFGFYEVFKVL 146
           G+ P +L      +  F  YE  K L
Sbjct: 295 GFWPNWLRLGPWNIIFFITYEQLKRL 320


>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
          Length = 338

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 70/314 (22%), Positives = 127/314 (40%), Gaps = 62/314 (19%)

Query: 77  LTHTAVVPLDLVKCRMQVD----------------------------------PQKYKGI 102
           LT   V PLD+VK R+Q                                    P  ++G 
Sbjct: 28  LTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKLWYKKPGNFQGT 87

Query: 103 FNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTS 162
            + F   ++ +G++ L  G  PT +      +  F  Y+    L  + LGE  T      
Sbjct: 88  LDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENET-----C 142

Query: 163 LYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPL 222
           + + A   A F A   ++P+E  + ++Q++      L     K   E+G  + ++G AP 
Sbjct: 143 IPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISLWRGWAPT 202

Query: 223 WMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHP 282
            +R +P++ M    +    E L K++  K  S   +P   ++ F +G ++G F A+ + P
Sbjct: 203 VLRDVPFSAM----YWYNYEILKKWLCEK--SGLYEP-TFMINFTSGALSGSFAAVATLP 255

Query: 283 ADSVVS------------VLNKEKGSSASLVLKRL----GFKGVWKGLFARIIMIGTLTA 326
            D V +             ++     S  +++K +    GF G++ GL  R+I I    A
Sbjct: 256 FDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACA 315

Query: 327 LQWFIYDSVKVYFR 340
           +    Y+  K +F+
Sbjct: 316 IMISTYEFGKAFFQ 329


>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
          Length = 338

 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 65/288 (22%), Positives = 113/288 (39%), Gaps = 33/288 (11%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQV---DPQ-KYKGIFNGFSVTLKEDGVRGLAKGWAPTF 126
           G ++  L H+ + P+D VK RMQ    DP+ +Y  I+      ++ +G     +G     
Sbjct: 52  GAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMI 111

Query: 127 LGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAK 186
           +G        F  YE  K   +++   +        +   A + A    D  + P E  K
Sbjct: 112 MGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGI---AGSMATLLHDAVMNPAEVVK 168

Query: 187 VRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYK 246
            R+Q       +       +++ EGL AFY+         IP+  + F  +E   E +  
Sbjct: 169 QRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNP 228

Query: 247 FVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL------ 300
                P+S            ++G +AG   A  + P D   ++LN ++  + SL      
Sbjct: 229 HRTYNPQSH----------IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGR 278

Query: 301 ----------VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVY 338
                     V +  G  G +KG+ AR+I     TA+ W +Y+  K +
Sbjct: 279 LSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYF 326


>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
          Length = 468

 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 68/279 (24%), Positives = 122/279 (43%), Gaps = 23/279 (8%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLG 128
           G ++  ++ T   PLD +K  MQV   K     I  G    + E G+R L +G     L 
Sbjct: 192 GAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINVLK 251

Query: 129 YSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVR 188
            + +   KF  YE  K     +LG++ T   +      + A A   A   + PME  K R
Sbjct: 252 IAPESAIKFMAYEQIK---RAILGQQETLHVQERFVAGSLAGAT--AQTIIYPMEVLKTR 306

Query: 189 IQ-TQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKF 247
           +   + G    L D A ++ + EG +AFY+G  P  +  IPY  +  A +    E L  +
Sbjct: 307 LTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVY----ETLKNW 362

Query: 248 VVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNK----EKGSSASL--- 300
            + +   + + P  ++V    G I+     I S+P   V + +      E G   S+   
Sbjct: 363 WLQQYSHDSADP-GILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGL 421

Query: 301 ---VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 336
              +L + G +G+++G+    + +    ++ + +Y+++K
Sbjct: 422 LRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMK 460



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 41/179 (22%), Positives = 77/179 (43%), Gaps = 6/179 (3%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQVDPQ-KYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGY 129
           G L+     T + P++++K R+ +    +YKG+ +     L+ +G R   +G+ P  LG 
Sbjct: 286 GSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGI 345

Query: 130 SMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRI 189
                     YE  K  +      ++       L LA    +     IA  P+   + R+
Sbjct: 346 IPYAGIDLAVYETLKNWWLQQYSHDSADPGILVL-LACGTISSTCGQIASYPLALVRTRM 404

Query: 190 QTQP----GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEAL 244
           Q Q     G   ++      +  +EG++  Y+G+AP +M+ IP   + +  +E   +AL
Sbjct: 405 QAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463


>gi|21361114 solute carrier family 25 (mitochondrial carrier;
           oxoglutarate carrier), member 11 [Homo sapiens]
          Length = 314

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 73/297 (24%), Positives = 125/297 (42%), Gaps = 37/297 (12%)

Query: 69  FGGVLSCGLTHTAVVPLDLVKCRMQVDPQ-----KYKGIFNGFSVTLKEDGVRGLAKGWA 123
           FGG+   G T   V PLDLVK RMQ+  +     +YK  F+  +  LK +G+RG+  G +
Sbjct: 27  FGGLAGMGAT-VFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGLS 85

Query: 124 PTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENT---YLWRTSLYLAASASAEFF---ADI 177
              L  +     + G Y    VL+  + G + T   +L +  + + A A+  F    A++
Sbjct: 86  AGLLRQATYTTTRLGIY---TVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEV 142

Query: 178 ALAPMEA-AKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFAC 236
           AL  M A  ++    + GY N   +A  ++ +EEG+   ++G  P   R +     + A 
Sbjct: 143 ALIRMTADGRLPADQRRGYKNVF-NALIRITREEGVLTLWRGCIPTMARAVVVNAAQLAS 201

Query: 237 FERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGS 296
           + ++ + L               + ++  F A  I+G+     S P D   + +   +  
Sbjct: 202 YSQSKQFLL--------DSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMI 253

Query: 297 SAS-----------LVLKRLGFKGVWKGLFARIIMIGTLTALQW-FIYDSVKVYFRL 341
                          V++  GF  +WKG       +G  T L + F+    K Y RL
Sbjct: 254 DGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRL 310


>gi|11225256 uncoupling protein 1 [Homo sapiens]
          Length = 307

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 52/204 (25%), Positives = 93/204 (45%), Gaps = 20/204 (9%)

Query: 57  EFGSAKYYALCGFGGVLSCGLTHTAVV-----PLDLVKCRMQVDPQ------KYKGIFNG 105
           EF +A        G  +  GLT   V      P ++VK R+Q          +Y G +N 
Sbjct: 101 EFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNA 160

Query: 106 FSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLY--SNMLGEENTYLWRTSL 163
           + +    +G+ GL KG  P  +   +    +   Y++ K  +  +N+L ++         
Sbjct: 161 YRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNILADD------VPC 214

Query: 164 YLAASASAEFFADIALAPMEAAKVR-IQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPL 222
           +L ++  A F A    +P++  K R I + PG   ++ + A K++  EG  AF+KG+ P 
Sbjct: 215 HLVSALIAGFCATAMSSPVDVVKTRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPS 274

Query: 223 WMRQIPYTMMKFACFERTVEALYK 246
           ++R   + ++ F CFE+    L K
Sbjct: 275 FLRLGSWNVIMFVCFEQLKRELSK 298



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 65/289 (22%), Positives = 103/289 (35%), Gaps = 39/289 (13%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQVDPQ-------KYKGIFNGFSVTLKEDGVRGLAKGWA 123
           G+ +C L      PLD  K R+QV  +       +YKG+    +  +K +G   L  G  
Sbjct: 21  GIAAC-LADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMKLYSGLP 79

Query: 124 PTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLY--LAASASAEFFADIALAP 181
                       + G Y+  +   +   G+E      + +   L     A F       P
Sbjct: 80  AGLQRQISSASLRIGLYDTVQEFLT--AGKETAPSLGSKILAGLTTGGVAVFIGQ----P 133

Query: 182 MEAAKVRIQTQ-------PGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKF 234
            E  KVR+Q Q       P Y  T  +A   +   EGL   +KG  P  MR +     + 
Sbjct: 134 TEVVKVRLQAQSHLHGIKPRYTGTY-NAYRIIATTEGLTGLWKGTTPNLMRSVIINCTEL 192

Query: 235 ACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSV-VSVLNKE 293
             ++   EA  K  +      C          V+  IAG     +S P D V    +N  
Sbjct: 193 VTYDLMKEAFVKNNILADDVPCH--------LVSALIAGFCATAMSSPVDVVKTRFINSP 244

Query: 294 KGSSASL------VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 336
            G   S+      V    G    +KGL    + +G+   + +  ++ +K
Sbjct: 245 PGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQLK 293



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 40/195 (20%), Positives = 67/195 (34%), Gaps = 29/195 (14%)

Query: 165 LAASASAEFFADIALAPMEAAKVRIQTQPGYANT--------LRDAAPKMYKEEGLKAFY 216
           L ++  A   AD+   P++ AKVR+Q Q G   T        +      + K EG    Y
Sbjct: 17  LFSAGIAACLADVITFPLDTAKVRLQVQ-GECPTSSVIRYKGVLGTITAVVKTEGRMKLY 75

Query: 217 KGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFC 276
            G+     RQI    ++   ++   E L       P         L    +AG   G   
Sbjct: 76  SGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAP--------SLGSKILAGLTTGGVA 127

Query: 277 AIVSHPADSVVSVLNKEKG------------SSASLVLKRLGFKGVWKGLFARIIMIGTL 324
             +  P + V   L  +              ++  ++    G  G+WKG    ++    +
Sbjct: 128 VFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVII 187

Query: 325 TALQWFIYDSVKVYF 339
              +   YD +K  F
Sbjct: 188 NCTELVTYDLMKEAF 202


>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
          Length = 318

 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 60/205 (29%), Positives = 91/205 (44%), Gaps = 21/205 (10%)

Query: 49  AAVEEYSCEFGSAKYYALCG---------FGGVLSCGLTHTAVVPLDLVKCRMQVDPQK- 98
           +A EEY    GS  YY   G         F G L+     +   PLDLV+ RM V P++ 
Sbjct: 109 SAHEEYKRILGS--YYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVRARMAVTPKEM 166

Query: 99  YKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYL 158
           Y  IF+ F    +E+G++ L  G+ PT LG        F  YE  K L+    G    Y 
Sbjct: 167 YSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYP 226

Query: 159 WRTSLYLAASA----SAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEG-LK 213
           +   ++ A +     SA +  D+    M+ A V    +   A TLR     + +EEG ++
Sbjct: 227 FERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRASIARTLR----TIVREEGAVR 282

Query: 214 AFYKGVAPLWMRQIPYTMMKFACFE 238
             YKG++  W++      + F  F+
Sbjct: 283 GLYKGLSMNWVKGPIAVGISFTTFD 307



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 69/286 (24%), Positives = 118/286 (41%), Gaps = 27/286 (9%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQVDPQKY--KGIFNGFSVTLKEDGVRGLAKGWAPTFLG 128
           G L+  L  TAV PLD  K   QV  +++  K  F     T   +G   L +G + T + 
Sbjct: 40  GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSATMVR 99

Query: 129 YSMQGLCKFGFYEVFKVLYSNMLGEENTYL--WRTSLYLAASASAEFFADIALAPMEAAK 186
                  +F  +E +K +  +  G     L  W     L A A A   A     P++  +
Sbjct: 100 VVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPR---LFAGALAGTTAASLTYPLDLVR 156

Query: 187 VRIQTQPG--YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEAL 244
            R+   P   Y+N       ++ +EEGLK  Y G  P  +  IPY  + F  +E T+++L
Sbjct: 157 ARMAVTPKEMYSNIFH-VFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYE-TLKSL 214

Query: 245 YKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSV------VSVLNKEKGSSA 298
           ++      R +    E+++     G  AG+     S+P D V        V    + S A
Sbjct: 215 HREY--SGRRQPYPFERMIF----GACAGLIGQSASYPLDVVRRRMQTAGVTGYPRASIA 268

Query: 299 ----SLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFR 340
               ++V +    +G++KGL    +       + +  +D +++  R
Sbjct: 269 RTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQIMLR 314


>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
           sapiens]
          Length = 675

 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 73/282 (25%), Positives = 115/282 (40%), Gaps = 40/282 (14%)

Query: 80  TAVVPLDLVKCRMQ--------VDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSM 131
           TAV P+DLVK RMQ        V    YK  F+ F   L+ +G  GL +G  P  LG + 
Sbjct: 344 TAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAP 403

Query: 132 QGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFAD----IALAPMEAAKV 187
           +   K    +  +  + +  G         S+ LAA   A   A     I   P+E  K+
Sbjct: 404 EKAIKLTVNDFVRDKFMHKDG---------SVPLAAEILAGGCAGGSQVIFTNPLEIVKI 454

Query: 188 RIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKF 247
           R+Q         R +A  + ++ G    YKG    ++R IP++ + F C+     A  K 
Sbjct: 455 RLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY-----AHVKA 509

Query: 248 VVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL------- 300
                  + S    L    +AG IAG+  A +  PAD + + L     +  +        
Sbjct: 510 SFANEDGQVSPGSLL----LAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDC 565

Query: 301 ---VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYF 339
              +L+  G K +WKG  AR+        +    Y+ ++ +F
Sbjct: 566 FRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWF 607


>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
           sapiens]
          Length = 676

 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 73/282 (25%), Positives = 115/282 (40%), Gaps = 40/282 (14%)

Query: 80  TAVVPLDLVKCRMQ--------VDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSM 131
           TAV P+DLVK RMQ        V    YK  F+ F   L+ +G  GL +G  P  LG + 
Sbjct: 345 TAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAP 404

Query: 132 QGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFAD----IALAPMEAAKV 187
           +   K    +  +  + +  G         S+ LAA   A   A     I   P+E  K+
Sbjct: 405 EKAIKLTVNDFVRDKFMHKDG---------SVPLAAEILAGGCAGGSQVIFTNPLEIVKI 455

Query: 188 RIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKF 247
           R+Q         R +A  + ++ G    YKG    ++R IP++ + F C+     A  K 
Sbjct: 456 RLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY-----AHVKA 510

Query: 248 VVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL------- 300
                  + S    L    +AG IAG+  A +  PAD + + L     +  +        
Sbjct: 511 SFANEDGQVSPGSLL----LAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDC 566

Query: 301 ---VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYF 339
              +L+  G K +WKG  AR+        +    Y+ ++ +F
Sbjct: 567 FRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWF 608


>gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]
          Length = 312

 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 48/185 (25%), Positives = 82/185 (44%), Gaps = 13/185 (7%)

Query: 71  GVLSCGLTHTAVVPLDLVKCRMQVD--------PQKYKGIFNGFSVTLKEDGVRGLAKGW 122
           G  +  +  T   P D+VK R Q           +KY G  + +    +E+GVRGL KG 
Sbjct: 123 GCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGT 182

Query: 123 APTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPM 182
            P  +  ++    +   Y++ K      L + +        +  ++  A F A +  +P+
Sbjct: 183 LPNIMRNAIVNCAEVVTYDILK----EKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPV 238

Query: 183 EAAKVR-IQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTV 241
           +  K R + + PG   +  D   KM  +EG  AFYKG  P ++R   + ++ F  +E+  
Sbjct: 239 DVVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLK 298

Query: 242 EALYK 246
            AL K
Sbjct: 299 RALMK 303



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 42/194 (21%), Positives = 77/194 (39%), Gaps = 34/194 (17%)

Query: 168 SASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMY-----------KEEGLKAFY 216
           + +A  FAD+   P++ AKVR+Q Q G    ++ A    Y           + EG  + Y
Sbjct: 20  AGTAACFADLVTFPLDTAKVRLQIQ-GENQAVQTARLVQYRGVLGTILTMVRTEGPCSPY 78

Query: 217 KGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFC 276
            G+     RQ+ +  ++   ++ +V+ +Y    PK     S    L    +AG   G   
Sbjct: 79  NGLVAGLQRQMSFASIRIGLYD-SVKQVY---TPKGADNSS----LTTRILAGCTTGAMA 130

Query: 277 AIVSHPADSV---------VSVLNKEKGSSASL-----VLKRLGFKGVWKGLFARIIMIG 322
              + P D V         +     ++  S ++     + +  G +G+WKG    I+   
Sbjct: 131 VTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNA 190

Query: 323 TLTALQWFIYDSVK 336
            +   +   YD +K
Sbjct: 191 IVNCAEVVTYDILK 204


>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
          Length = 332

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 78/305 (25%), Positives = 124/305 (40%), Gaps = 33/305 (10%)

Query: 63  YYALCGF--GGVLSCGLTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGL 118
           +Y L  F  GG+  C    T V PLD VK  +Q     YK  G+F+      +++G  GL
Sbjct: 34  FYWLRSFLAGGIAGC-CAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGL 92

Query: 119 AKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIA 178
            KG     +     G  +F  +E +K L +  LG    ++ R    L A + A   A I 
Sbjct: 93  YKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISG-HVHR----LMAGSMAGMTAVIC 147

Query: 179 LAPMEAAKVR----IQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKF 234
             P++  +VR    ++ +  Y   +        KE G   FY+G+ P  +   PY  + F
Sbjct: 148 TYPLDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSF 207

Query: 235 ACFERTVEALYKFVVPK--PRSECSKPEQLV----VTFVAGYIAGVFCAIVSHPAD---- 284
             F  T++++     P    R     P  LV    V  + G +AG     +S+P D    
Sbjct: 208 FTF-GTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRR 266

Query: 285 -----SVVSVLNK--EKGSSASLVLKRLGF-KGVWKGLFARIIMIGTLTALQWFIYDSVK 336
                +V+    K      +   V    G  KG+++GL    I      A+ +  Y+ +K
Sbjct: 267 RMQLGTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMK 326

Query: 337 VYFRL 341
            +F L
Sbjct: 327 QFFHL 331


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,662,747
Number of Sequences: 37866
Number of extensions: 647513
Number of successful extensions: 2450
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2058
Number of HSP's gapped (non-prelim): 175
length of query: 361
length of database: 18,247,518
effective HSP length: 104
effective length of query: 257
effective length of database: 14,309,454
effective search space: 3677529678
effective search space used: 3677529678
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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