Guide to the Human Genome
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Search of human proteins with 47078295

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47078295 adenosine deaminase [Homo sapiens]
         (363 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47078295 adenosine deaminase [Homo sapiens]                        739   0.0  
gi|61175224 adenosine deaminase-like isoform 2 [Homo sapiens]          59   9e-09
gi|226693318 adenosine deaminase-like isoform 1 [Homo sapiens]         55   8e-08
gi|29029552 cat eye syndrome critical region protein 1 isoform b...    46   5e-05
gi|29029550 cat eye syndrome critical region protein 1 isoform a...    46   5e-05
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]          29   7.5  
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s...    28   9.8  

>gi|47078295 adenosine deaminase [Homo sapiens]
          Length = 363

 Score =  739 bits (1908), Expect = 0.0
 Identities = 363/363 (100%), Positives = 363/363 (100%)

Query: 1   MAQTPAFDKPKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPD 60
           MAQTPAFDKPKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPD
Sbjct: 1   MAQTPAFDKPKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPD 60

Query: 61  FLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQA 120
           FLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQA
Sbjct: 61  FLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQA 120

Query: 121 EGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAI 180
           EGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAI
Sbjct: 121 EGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAI 180

Query: 181 DLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGY 240
           DLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGY
Sbjct: 181 DLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGY 240

Query: 241 HTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIF 300
           HTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIF
Sbjct: 241 HTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIF 300

Query: 301 KSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAG 360
           KSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAG
Sbjct: 301 KSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAG 360

Query: 361 QNL 363
           QNL
Sbjct: 361 QNL 363


>gi|61175224 adenosine deaminase-like isoform 2 [Homo sapiens]
          Length = 267

 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 54/235 (22%), Positives = 107/235 (45%), Gaps = 25/235 (10%)

Query: 10  PKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPDFLAKFDYYM 69
           PKVELH HL+GSI   T+    ++     P       + VI   K  TL +    F   +
Sbjct: 19  PKVELHAHLNGSISSHTM----KKLIAQKPDLKIHDQMTVIDKGKKRTLEECFQMFQ-TI 73

Query: 70  PAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEV 129
             +    E I  +  + ++  A +GV Y+E+R +P              +    +T    
Sbjct: 74  HQLTSSPEDILMVTKDVIKEFADDGVKYLELRSTPR------------RENATGMTKKTY 121

Query: 130 VALVGQGLQEGERD-FGVKARSILCC-MRHQPNWSPKVVELCKKY---QQQTVVAIDLAG 184
           V  + +G+++ +++   +  R ++    R  P  + + V+L +++    + TV+ +DL+G
Sbjct: 122 VESILEGIKQSKQENLDIDVRYLIAVDRRGGPLVAKETVKLAEEFFLSTEGTVLGLDLSG 181

Query: 185 DETIPGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHG 239
           D T+  +      ++   EA K+G+   +H  E+ + +   + +  L  +R+GHG
Sbjct: 182 DPTVGQAK---DFLEPLLEAKKAGLKLALHLSEIPNQKKETQILLDLLPDRIGHG 233


>gi|226693318 adenosine deaminase-like isoform 1 [Homo sapiens]
          Length = 328

 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 73/347 (21%), Positives = 140/347 (40%), Gaps = 64/347 (18%)

Query: 10  PKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPDFLAKFDYYM 69
           PKVELH HL+GSI   T+    ++     P       + VI   K  TL +    F   +
Sbjct: 19  PKVELHAHLNGSISSHTM----KKLIAQKPDLKIHDQMTVIDKGKKRTLEECFQMFQ-TI 73

Query: 70  PAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEV 129
             +    E I  +  + ++  A +GV Y+E+R +P              +    +T    
Sbjct: 74  HQLTSSPEDILMVTKDVIKEFADDGVKYLELRSTPR------------RENATGMTKKTY 121

Query: 130 VALVGQGLQEGERD-FGVKARSILCC-MRHQPNWSPKVVELCKKY---QQQTVVAIDLAG 184
           V  + +G+++ +++   +  R ++    R  P  + + V+L +++    + TV+ +DL+G
Sbjct: 122 VESILEGIKQSKQENLDIDVRYLIAVDRRGGPLVAKETVKLAEEFFLSTEGTVLGLDLSG 181

Query: 185 DETIPGS--------SLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERL 236
           D TIP           LLP  +         G    +++GE GS ++    VD ++  R+
Sbjct: 182 DPTIPNQKKETQILLDLLPDRI---------GHGTFLNSGEGGSLDL----VDFVRQHRI 228

Query: 237 GHGYHTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDD 296
                   +  L + ++ +     +  +  +  G W      +VI            TDD
Sbjct: 229 P------LELCLTSNVKSQT----VPSYDQHHFGFWYSIAHPSVI-----------CTDD 267

Query: 297 PLIFKSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKREL 343
             +F + L  +YQ+       T+ +   L+  +    F  +  + EL
Sbjct: 268 KGVFATHLSQEYQLAAETFNLTQSQVWDLSYESINYIFASDSTRSEL 314


>gi|29029552 cat eye syndrome critical region protein 1 isoform b
           [Homo sapiens]
          Length = 270

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 49/187 (26%), Positives = 83/187 (44%), Gaps = 13/187 (6%)

Query: 176 TVVA-IDLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTV--HAGEVG--SAEVVKEAVD- 229
           TVVA  DL G E    S  L  + +A     K G+      HAGE       + +  +D 
Sbjct: 76  TVVAGFDLVGHEDTGHS--LHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNILDA 133

Query: 230 -ILKTERLGHGYHTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQA 288
            +L T R+GHG+   +  A+     ++++  E+CP S+ +         H V  L     
Sbjct: 134 LMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATGH 193

Query: 289 NYSLNTDDPLIFKST-LDTDYQMTKRDMGFTEEE---FKRLNINAAKSSFLPEDEKRELL 344
              +++DDP +F +  L  D+      +G  + +    K+L +N+ K S L E EK   +
Sbjct: 194 PMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFM 253

Query: 345 DLLYKAY 351
           ++  K +
Sbjct: 254 EIWKKRW 260


>gi|29029550 cat eye syndrome critical region protein 1 isoform a
           precursor [Homo sapiens]
          Length = 511

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 49/187 (26%), Positives = 83/187 (44%), Gaps = 13/187 (6%)

Query: 176 TVVA-IDLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTV--HAGEVG--SAEVVKEAVD- 229
           TVVA  DL G E    S  L  + +A     K G+      HAGE       + +  +D 
Sbjct: 317 TVVAGFDLVGHEDTGHS--LHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNILDA 374

Query: 230 -ILKTERLGHGYHTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQA 288
            +L T R+GHG+   +  A+     ++++  E+CP S+ +         H V  L     
Sbjct: 375 LMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATGH 434

Query: 289 NYSLNTDDPLIFKST-LDTDYQMTKRDMGFTEEE---FKRLNINAAKSSFLPEDEKRELL 344
              +++DDP +F +  L  D+      +G  + +    K+L +N+ K S L E EK   +
Sbjct: 435 PMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFM 494

Query: 345 DLLYKAY 351
           ++  K +
Sbjct: 495 EIWKKRW 501


>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
          Length = 1300

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 1/38 (2%)

Query: 143 DFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAI 180
           D   K ++++CC R  P     +V L KKY Q   +AI
Sbjct: 901 DLASKCQAVICC-RVTPKQKALIVALVKKYHQVVTLAI 937


>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
           sapiens]
          Length = 1223

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 17/50 (34%), Positives = 27/50 (54%), Gaps = 4/50 (8%)

Query: 149 RSILCCMRHQPNWSPKVVELCKKYQQQTVVAIDLAGDETIPGSSLLPGHV 198
           ++++CC R  P    +VVEL KKY++   +AI   GD     S +   H+
Sbjct: 815 KAVICC-RVTPLQKAQVVELVKKYKKAVTLAI---GDGANDVSMIKTAHI 860


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,952,672
Number of Sequences: 37866
Number of extensions: 613096
Number of successful extensions: 1451
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1440
Number of HSP's gapped (non-prelim): 8
length of query: 363
length of database: 18,247,518
effective HSP length: 104
effective length of query: 259
effective length of database: 14,309,454
effective search space: 3706148586
effective search space used: 3706148586
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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