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Search of human proteins with 46852147
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo
sapiens]
(1012 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens] 2065 0.0
gi|94721239 isoleucine tRNA synthetase [Homo sapiens] 282 1e-75
gi|94721241 isoleucine tRNA synthetase [Homo sapiens] 282 1e-75
gi|5454158 valyl-tRNA synthetase [Homo sapiens] 193 6e-49
gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens] 184 4e-46
gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Ho... 61 5e-09
gi|108773810 leucyl-tRNA synthetase [Homo sapiens] 49 2e-05
gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens] 35 0.47
gi|14043022 methionyl-tRNA synthetase [Homo sapiens] 32 3.0
gi|114431248 hypothetical protein LOC205717 [Homo sapiens] 32 3.9
gi|157885806 chromosome 12 open reading frame 51 [Homo sapiens] 31 6.7
gi|46852172 kinesin family member 13B [Homo sapiens] 31 6.7
gi|40217847 activating signal cointegrator 1 complex subunit 3-l... 30 8.8
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 30 8.8
>gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens]
Length = 1012
Score = 2065 bits (5349), Expect = 0.0
Identities = 1012/1012 (100%), Positives = 1012/1012 (100%)
Query: 1 MRWGLRPRGPGAAALATARSLWGTPRLPCSPGWQGATKRLLVRSVSGASNHQPNSNSGRY 60
MRWGLRPRGPGAAALATARSLWGTPRLPCSPGWQGATKRLLVRSVSGASNHQPNSNSGRY
Sbjct: 1 MRWGLRPRGPGAAALATARSLWGTPRLPCSPGWQGATKRLLVRSVSGASNHQPNSNSGRY 60
Query: 61 RDTVLLPQTSFPMKLLGRQQPDTELEIQQKCGFSELYSWQRERKVKTEFCLHDGPPYANG 120
RDTVLLPQTSFPMKLLGRQQPDTELEIQQKCGFSELYSWQRERKVKTEFCLHDGPPYANG
Sbjct: 61 RDTVLLPQTSFPMKLLGRQQPDTELEIQQKCGFSELYSWQRERKVKTEFCLHDGPPYANG 120
Query: 121 DPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSELGREAQNLSAMEI 180
DPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSELGREAQNLSAMEI
Sbjct: 121 DPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSELGREAQNLSAMEI 180
Query: 181 RKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQMYDKGLVYRSY 240
RKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQMYDKGLVYRSY
Sbjct: 181 RKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQMYDKGLVYRSY 240
Query: 241 KPVFWSPSSRTALAEAELEYNPEHVSRSIYVKFPLLKPSPKLASLIDGSSPVSILVWTTQ 300
KPVFWSPSSRTALAEAELEYNPEHVSRSIYVKFPLLKPSPKLASLIDGSSPVSILVWTTQ
Sbjct: 241 KPVFWSPSSRTALAEAELEYNPEHVSRSIYVKFPLLKPSPKLASLIDGSSPVSILVWTTQ 300
Query: 301 PWTIPANEAVCYMPESKYAVVKCSKSGDLYVLAADKVASVASTLETTFETISTLSGVDLE 360
PWTIPANEAVCYMPESKYAVVKCSKSGDLYVLAADKVASVASTLETTFETISTLSGVDLE
Sbjct: 301 PWTIPANEAVCYMPESKYAVVKCSKSGDLYVLAADKVASVASTLETTFETISTLSGVDLE 360
Query: 361 NGTCSHPLIPDKASPLLPANHVTMAKGTGLVHTAPAHGMEDYGVASQHNLPMDCLVDEDG 420
NGTCSHPLIPDKASPLLPANHVTMAKGTGLVHTAPAHGMEDYGVASQHNLPMDCLVDEDG
Sbjct: 361 NGTCSHPLIPDKASPLLPANHVTMAKGTGLVHTAPAHGMEDYGVASQHNLPMDCLVDEDG 420
Query: 421 VFTDVAGPELQNKAVLEEGTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQ 480
VFTDVAGPELQNKAVLEEGTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQ
Sbjct: 421 VFTDVAGPELQNKAVLEEGTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQ 480
Query: 481 WFINITDIKTAAKELLKKVKFIPGSALNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTK 540
WFINITDIKTAAKELLKKVKFIPGSALNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTK
Sbjct: 481 WFINITDIKTAAKELLKKVKFIPGSALNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTK 540
Query: 541 DEYLINSQTTEHIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIW 600
DEYLINSQTTEHIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIW
Sbjct: 541 DEYLINSQTTEHIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIW 600
Query: 601 FDSGTSWSYVLPGPDQRADLYLEGKDQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTLGE 660
FDSGTSWSYVLPGPDQRADLYLEGKDQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTLGE
Sbjct: 601 FDSGTSWSYVLPGPDQRADLYLEGKDQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTLGE 660
Query: 661 KGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAIGPSVLNAAR 720
KGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAIGPSVLNAAR
Sbjct: 661 KGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAIGPSVLNAAR 720
Query: 721 DDISKLRNTLRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQYDFG 780
DDISKLRNTLRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQYDFG
Sbjct: 721 DDISKLRNTLRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQYDFG 780
Query: 781 KVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPILPH 840
KVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPILPH
Sbjct: 781 KVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPILPH 840
Query: 841 LAEEVFQHIPYIKEPKSVFRTGWISTSSIWKKPGLEEAVESACAMRDSFLGSIPGKNAAE 900
LAEEVFQHIPYIKEPKSVFRTGWISTSSIWKKPGLEEAVESACAMRDSFLGSIPGKNAAE
Sbjct: 841 LAEEVFQHIPYIKEPKSVFRTGWISTSSIWKKPGLEEAVESACAMRDSFLGSIPGKNAAE 900
Query: 901 YKVITVIEPGLLFEIIEMLQSEETSSTSQLNELMMASESTLLAQEPREMTADVIELKGKF 960
YKVITVIEPGLLFEIIEMLQSEETSSTSQLNELMMASESTLLAQEPREMTADVIELKGKF
Sbjct: 901 YKVITVIEPGLLFEIIEMLQSEETSSTSQLNELMMASESTLLAQEPREMTADVIELKGKF 960
Query: 961 LINLEGGDIREESSYKVIVMPTTKEKCPRCWKYTAESSDTLCPRCAEVVSGK 1012
LINLEGGDIREESSYKVIVMPTTKEKCPRCWKYTAESSDTLCPRCAEVVSGK
Sbjct: 961 LINLEGGDIREESSYKVIVMPTTKEKCPRCWKYTAESSDTLCPRCAEVVSGK 1012
>gi|94721239 isoleucine tRNA synthetase [Homo sapiens]
Length = 1262
Score = 282 bits (722), Expect = 1e-75
Identities = 252/878 (28%), Positives = 393/878 (44%), Gaps = 107/878 (12%)
Query: 101 RERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPI 160
++ K K +F +DGPP+A G PH GH L +KDI R+ +G + GWDCHGLP+
Sbjct: 33 KQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPV 92
Query: 161 EIKVLSELG----REAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFD 216
E ++ LG + + E + R+ + KS R G D++N Y T
Sbjct: 93 EYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLY 152
Query: 217 GKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHV-SRSIYVKFPL 275
++ F Q+YDKGLVYR K + +S + T L+ E N + V S++V FPL
Sbjct: 153 PQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVFVTFPL 212
Query: 276 LKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMPESKYAVVKCSKSGDLYVLAAD 335
+ VS++ WTT PWT+P+N AVC PE +Y +K G L +L
Sbjct: 213 -----------EEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEA 261
Query: 336 KVASVASTLETTFETISTLSGVDLENGTCSHPLI-------PDKASPLLPANHVTMAKGT 388
+++++ LE+ +E + G L+ G PL + A +L N+V +GT
Sbjct: 262 RLSALYK-LESDYEILERFPGAYLK-GKKYRPLFDYFLKCKENGAFTVLVDNYVKEEEGT 319
Query: 389 GLVHTAPAHGMEDYGVASQHN------LPMDCLVDEDGVF----TDVAGPELQNKAVLEE 438
G+VH AP G EDY V N LP+ C VD G F TD AG +++
Sbjct: 320 GVVHQAPYFGAEDYRVCMDFNIIRKDSLPV-CPVDASGCFTTEVTDFAG------QYVKD 372
Query: 439 GTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQWFINI----------TDI 488
+I+ L+ LL HSYP+ WR+ P++ +A WF+ + D+
Sbjct: 373 ADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDL 432
Query: 489 KTAAKELLKKVKFIPGSALNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQ 548
EL+++ +F N + + D W ISR R WG PIP++ +E +
Sbjct: 433 CYWVPELVREKRF-----GNWLKDARD----WTISRNRYWGTPIPLWVSDDFEEVVCIGS 483
Query: 549 TTEHIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIWFDSGTSWS 608
E + +L SD+ +P G +L + ++ D WF+SG S
Sbjct: 484 VAE-LEELSGAKISDLHRESVDHLTIPSRC-----GKGSLHRI--SEVFDCWFESG-SMP 534
Query: 609 YV---LPGPDQR-------ADLYLEGKDQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTL 658
Y P ++R AD EG DQ GWF + L+ + A + P+K VIV+G L
Sbjct: 535 YAQVHYPFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVL 594
Query: 659 GEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAI---GPSV 715
G+KMSK N +PD V S YGAD LR ++ +S V + V
Sbjct: 595 ASDGQKMSKRKKN--YPDPV-------SIIQKYGADALRLYLINSPVVRAENLRFKEEGV 645
Query: 716 LNAARDDISKLRNTLRFLLGNVADFNPE-------TDSIPVNDMYVIDQYMLHLLQDLAN 768
+ +D + N RFL+ NV E ++ + D+++L +Q L
Sbjct: 646 RDVLKDVLLPWYNAYRFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIG 705
Query: 769 KI-TELYKQYDFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEIL 827
TE+ + V RL++ + L+N+Y + + RL E + + +T L +L
Sbjct: 706 FFETEMAAYRLYTVVPRLVK--FVDILTNWYVRMNRRRLKGENGMEDCVMALET-LFSVL 762
Query: 828 DVIVRSFAPILPHLAEEVFQHIPYIKEPKSVFRTGWISTSSIWKKPGLEEAVESACAMRD 887
+ R AP P L E ++Q++ + +P SV +S + EE ++
Sbjct: 763 LSLCRLMAPYTPFLTELMYQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAV 822
Query: 888 SFLGSI--PGKNAAEYKVITVIEPGLLFEIIEMLQSEE 923
S + S+ G+ + K I + P L EI+ + Q E
Sbjct: 823 SQMQSVIELGRVIRDRKTIPIKYP--LKEIVVIHQDPE 858
>gi|94721241 isoleucine tRNA synthetase [Homo sapiens]
Length = 1262
Score = 282 bits (722), Expect = 1e-75
Identities = 252/878 (28%), Positives = 393/878 (44%), Gaps = 107/878 (12%)
Query: 101 RERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPI 160
++ K K +F +DGPP+A G PH GH L +KDI R+ +G + GWDCHGLP+
Sbjct: 33 KQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPV 92
Query: 161 EIKVLSELG----REAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFD 216
E ++ LG + + E + R+ + KS R G D++N Y T
Sbjct: 93 EYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLY 152
Query: 217 GKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHV-SRSIYVKFPL 275
++ F Q+YDKGLVYR K + +S + T L+ E N + V S++V FPL
Sbjct: 153 PQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVFVTFPL 212
Query: 276 LKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMPESKYAVVKCSKSGDLYVLAAD 335
+ VS++ WTT PWT+P+N AVC PE +Y +K G L +L
Sbjct: 213 -----------EEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEA 261
Query: 336 KVASVASTLETTFETISTLSGVDLENGTCSHPLI-------PDKASPLLPANHVTMAKGT 388
+++++ LE+ +E + G L+ G PL + A +L N+V +GT
Sbjct: 262 RLSALYK-LESDYEILERFPGAYLK-GKKYRPLFDYFLKCKENGAFTVLVDNYVKEEEGT 319
Query: 389 GLVHTAPAHGMEDYGVASQHN------LPMDCLVDEDGVF----TDVAGPELQNKAVLEE 438
G+VH AP G EDY V N LP+ C VD G F TD AG +++
Sbjct: 320 GVVHQAPYFGAEDYRVCMDFNIIRKDSLPV-CPVDASGCFTTEVTDFAG------QYVKD 372
Query: 439 GTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQWFINI----------TDI 488
+I+ L+ LL HSYP+ WR+ P++ +A WF+ + D+
Sbjct: 373 ADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDL 432
Query: 489 KTAAKELLKKVKFIPGSALNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQ 548
EL+++ +F N + + D W ISR R WG PIP++ +E +
Sbjct: 433 CYWVPELVREKRF-----GNWLKDARD----WTISRNRYWGTPIPLWVSDDFEEVVCIGS 483
Query: 549 TTEHIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIWFDSGTSWS 608
E + +L SD+ +P G +L + ++ D WF+SG S
Sbjct: 484 VAE-LEELSGAKISDLHRESVDHLTIPSRC-----GKGSLHRI--SEVFDCWFESG-SMP 534
Query: 609 YV---LPGPDQR-------ADLYLEGKDQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTL 658
Y P ++R AD EG DQ GWF + L+ + A + P+K VIV+G L
Sbjct: 535 YAQVHYPFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVL 594
Query: 659 GEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAI---GPSV 715
G+KMSK N +PD V S YGAD LR ++ +S V + V
Sbjct: 595 ASDGQKMSKRKKN--YPDPV-------SIIQKYGADALRLYLINSPVVRAENLRFKEEGV 645
Query: 716 LNAARDDISKLRNTLRFLLGNVADFNPE-------TDSIPVNDMYVIDQYMLHLLQDLAN 768
+ +D + N RFL+ NV E ++ + D+++L +Q L
Sbjct: 646 RDVLKDVLLPWYNAYRFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIG 705
Query: 769 KI-TELYKQYDFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEIL 827
TE+ + V RL++ + L+N+Y + + RL E + + +T L +L
Sbjct: 706 FFETEMAAYRLYTVVPRLVK--FVDILTNWYVRMNRRRLKGENGMEDCVMALET-LFSVL 762
Query: 828 DVIVRSFAPILPHLAEEVFQHIPYIKEPKSVFRTGWISTSSIWKKPGLEEAVESACAMRD 887
+ R AP P L E ++Q++ + +P SV +S + EE ++
Sbjct: 763 LSLCRLMAPYTPFLTELMYQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAV 822
Query: 888 SFLGSI--PGKNAAEYKVITVIEPGLLFEIIEMLQSEE 923
S + S+ G+ + K I + P L EI+ + Q E
Sbjct: 823 SQMQSVIELGRVIRDRKTIPIKYP--LKEIVVIHQDPE 858
>gi|5454158 valyl-tRNA synthetase [Homo sapiens]
Length = 1264
Score = 193 bits (491), Expect = 6e-49
Identities = 208/834 (24%), Positives = 337/834 (40%), Gaps = 125/834 (14%)
Query: 115 PPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSELGREAQN 174
PP G H+GHAL ++D R+H M G + PG D G+ ++ V +L RE Q
Sbjct: 343 PPNVTGSLHLGHALTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWRE-QG 401
Query: 175 LSAMEIRKKARSFAKAAIEKQKSAFI-----RWGIMADWNNCYYTFDGKYEAKQLRTFYQ 229
LS ++ ++A +++K I + G DW+ +T D K A F +
Sbjct: 402 LSRHQLGREAFLQEVWKWKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVR 461
Query: 230 MYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHVSRSIYVKFPLLKPSPKLASLID-- 287
++++G++YRS + V WS + +A+++ E++ E R++ + P K + L+
Sbjct: 462 LHEEGIIYRSTRLVNWSCTLNSAISDIEVD-KKELTGRTL-LSVPGYKEKVEFGVLVSFA 519
Query: 288 -----GSSPVSILVWTTQPWTIPANEAVCYMPESKYAVVKCSKSGDLYVLAADKVASVAS 342
S ++V TT+ T+ + AV P+
Sbjct: 520 YKVQGSDSDEEVVVATTRIETMLGDVAVAVHPK--------------------------- 552
Query: 343 TLETTFETISTLSGVDLENGTCSHPLIPDKASPLLPANHVTMAKGTGLVHTAPAHGMEDY 402
+T ++ L+ HP + ++ P++ V M GTG V PAH DY
Sbjct: 553 --DTRYQ--------HLKGKNVIHPFL-SRSLPIVFDEFVDMDFGTGAVKITPAHDQNDY 601
Query: 403 GVASQHNLPMDCLVDEDGVFTDVAGPEL------QNKAVLEEGTDVVIKMLQTAKNLLKE 456
V +H L ++D G +V P L KAVL V +K + +
Sbjct: 602 EVGQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVL-----VALKERGLFRGIEDN 656
Query: 457 EKLVHSYPYDWRTKKPVVIRASKQWFINITDIKTAAKELLKK--VKFIPGSALNGMVEMM 514
+V P R+K V QW++ ++ AA + + ++ +P + M
Sbjct: 657 PMVV---PLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHAWM 713
Query: 515 DRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIVKLVEQHGSDIWWTLPPEQLL 574
D WCISRQ WG IP + D V E W + E
Sbjct: 714 DNIREWCISRQLWWGHRIPAYFVTVSDP----------AVPPGEDPDGRYWVSGRNEAEA 763
Query: 575 PKEVLSEVG-GPDALEYVPGQDILDIWFDSGTSWSYVLPGPDQRADLYL--------EGK 625
++ E G PD + +D+LD WF SG +L P+Q DL + G
Sbjct: 764 REKAAKEFGVSPDKISLQQDEDVLDTWFSSGLFPLSILGWPNQSEDLSVFYPGTLLETGH 823
Query: 626 DQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHP-DVV------ 678
D L W ++ + R P++ V +H G KMSKSLGNVI P DV+
Sbjct: 824 DILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQ 883
Query: 679 ------VNGGQDQSKE---------------PPYGADVLRWWV-ADSNVFTEVAIGPSVL 716
+N D S+ P G D LR+ + A + ++ + + +
Sbjct: 884 GLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVNRI 943
Query: 717 NAARDDISKLRNTLRFLLGNVAD-FNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYK 775
R +KL N +F L + F P S P ++D+++ L + + ++
Sbjct: 944 LGYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQ 1003
Query: 776 QYDFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSC-QTALVEILDVIVRSF 834
YDF V +F+ EL + Y +K L D C + L LDV +R
Sbjct: 1004 AYDFPAVTTAQYSFWLYELCDVYLECLKPVL---NGVDQVAAECARQTLYTCLDVGLRLL 1060
Query: 835 APILPHLAEEVFQHIP--YIKEPKSVFRTGWISTSSI-WKKPGLEEAVESACAM 885
+P +P + EE+FQ +P + P S+ T + S WK P E A+E A ++
Sbjct: 1061 SPFMPFVTEELFQRLPRRMPQAPPSLCVTPYPEPSECSWKDPEAEAALELALSI 1114
>gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens]
Length = 1063
Score = 184 bits (467), Expect = 4e-46
Identities = 194/824 (23%), Positives = 325/824 (39%), Gaps = 130/824 (15%)
Query: 115 PPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLP----IEIKVLSELGR 170
PP G H+GHAL ++D R+H M G ++ +VPG D G+ +E ++ E G
Sbjct: 145 PPNVTGSLHIGHALTVAIQDALVRWHRMRGDQVLWVPGSDHAGIATQAVVEKQLWKERGV 204
Query: 171 EAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQM 230
LS ++ + +A + G DW+ +T D F ++
Sbjct: 205 RRHELSREAFLREVWQWKEAKGGEICEQLRALGASLDWDRECFTMDVGSSVAVTEAFVRL 264
Query: 231 YDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHVSRSIYVKFPLLKPSP-------KLA 283
Y GL+YR+++ V WS + R+A+++ E+E P + ++ P P+P +A
Sbjct: 265 YKAGLLYRNHQLVNWSCALRSAISDIEVENRP--LPGHTQLRLPGC-PTPVSFGLLFSVA 321
Query: 284 SLIDGSSPVSILVWTTQPWTIPANEAVCYMPE-SKYAVVKCSKSGDLYVLAADKVASVAS 342
+DG ++V TT+P T+P + AV P+ S+Y
Sbjct: 322 FPVDGEPDAEVVVGTTRPETLPGDVAVAVHPDDSRY------------------------ 357
Query: 343 TLETTFETISTLSGVDLENGTCSHPLIPDKASPLLPANHVTMAKGTGLVHTAPAHGMEDY 402
+ L G L + PL PL+ V GTG V PAH D
Sbjct: 358 ---------THLHGRQLRHPLMGQPL------PLITDYAVQPHVGTGAVKVTPAHSPADA 402
Query: 403 GVASQHNLPMDCLVDEDGVFTDVAGPELQ--NKAVLEEGTDVVIKMLQTAKNLLKEEKLV 460
+ ++H L ++ EDG T + G LQ ++ V E V+ + L ++
Sbjct: 403 EMGARHGLSPLNVIAEDGTMTSLCGDWLQGLHRFVAREKIMSVLSEWGLFRGLQNHPMVL 462
Query: 461 HSYPYDWRTKKPVVIRASKQWFINITDIKTAAKELLKK--VKFIPGSALNGMVEMMDRRP 518
P R+ + QWF+ ++ A + ++ ++ P
Sbjct: 463 ---PICSRSGDVIEYLLKNQWFVRCQEMGARAAKAVESGALELSPSFHQKNWQHWFSHIG 519
Query: 519 YWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIVKLVEQH--GSDIWWTLPPEQLLPK 576
WC+SRQ WG IP YL+ VE H G + W + + +
Sbjct: 520 DWCVSRQLWWGHQIPA--------YLV-----------VEDHAQGEEDCWVVGRSEAEAR 560
Query: 577 EVLSEVGGPDALEYVPGQD--ILDIWFDSGTSWSYVLPGPDQRADL-------YLE-GKD 626
EV +E+ G E +D +LD WF S L P + DL LE G D
Sbjct: 561 EVAAELTGRPGAELTLERDPDVLDTWFSSALFPFSALGWPQETPDLARFYPLSLLETGSD 620
Query: 627 QLGGWFQSSLLTSVAARKRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHPDVVVNGGQDQS 686
L W ++ + P+ V++H +G KMSKSLGNV+ P +++G + Q
Sbjct: 621 LLLFWVGRMVMLGTQLTGQLPFSKVLLHPMVRDRQGRKMSKSLGNVLDPRDIISGVEMQV 680
Query: 687 KE----------------------------PPYGADVLRWWVADSNVFT-EVAIGPSVLN 717
+ P G D LR+ + V ++ + S +
Sbjct: 681 LQEKLRSGNLDPAELAIVAAAQKKDFPHGIPECGTDALRFTLCSHGVQAGDLHLSVSEVQ 740
Query: 718 AARDDISKLRNTLRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQY 777
+ R +K+ N LRF+L + + + ++ +D ++L L A + +
Sbjct: 741 SCRHFCNKIWNALRFILNALGEKFVPQPAEELSPSSPMDAWILSRLALAAQECERGFLTR 800
Query: 778 DFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPI 837
+ V L F+ L + Y +K L+ + P+ L D+ +R AP+
Sbjct: 801 ELSLVTHALHHFWLHNLCDVYLEAVKPVLW----HSPRPLGPPQVLFSCADLGLRLLAPL 856
Query: 838 LPHLAEEVFQHI---PYIKEPKSVFRTGWISTSSI--WKKPGLE 876
+P LAEE++Q + P S+ + S S+ W++P LE
Sbjct: 857 MPFLAEELWQRLPPRPGCPPAPSISVAPYPSACSLEHWRQPELE 900
>gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Homo
sapiens]
Length = 903
Score = 61.2 bits (147), Expect = 5e-09
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 13/156 (8%)
Query: 104 KVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPIEIK 163
K K +F + PY +G H+GH + D RF M G ++ GWD GLP E
Sbjct: 79 KSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAE-- 136
Query: 164 VLSELGREAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFDGKYEAKQ 223
+A+E +S+ ++ I+ + R G+ W+ T Y
Sbjct: 137 -----------NAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWT 185
Query: 224 LRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELE 259
F ++Y+ GL Y+ V W P +T LA +++
Sbjct: 186 QYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVD 221
Score = 35.0 bits (79), Expect = 0.36
Identities = 13/22 (59%), Positives = 15/22 (68%)
Query: 515 DRRPYWCISRQRVWGVPIPVFH 536
D+ W ISRQR WG PIP+ H
Sbjct: 442 DKLKDWLISRQRYWGTPIPIVH 463
>gi|108773810 leucyl-tRNA synthetase [Homo sapiens]
Length = 1176
Score = 49.3 bits (116), Expect = 2e-05
Identities = 79/387 (20%), Positives = 142/387 (36%), Gaps = 73/387 (18%)
Query: 84 ELEIQQKCGFSELY----SWQRERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRF 139
E EIQQK ++ S ++ K ++ + PY NG H+GH + + A +
Sbjct: 17 EKEIQQKWDTERVFEVNASNLEKQTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGY 76
Query: 140 HMMNGSKIHFVPGWDCHGLPIEIKVLSELGREAQ--------------------NLSAME 179
+ G F G C G+PI+ +L RE + +
Sbjct: 77 QRLKGKCCLFPFGLHCTGMPIKA-CADKLKREIELYGCPPDFPDEEEEEEETSVKTEDII 135
Query: 180 IRKKARSFAKAAIEKQKSAFIRWGIM---------------------------------- 205
I+ KA+ A K S+ +WGIM
Sbjct: 136 IKDKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRM 195
Query: 206 ---ADWNNCYYTFDGK--YEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEY 260
DW + T D Y++ F + ++ + + +SP + + +
Sbjct: 196 GLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQT 255
Query: 261 NPEHVSRSIY--VKFPLLKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMPESKY 318
E V Y +K +L+P P S + G + + ++ T +P T+ P+ KY
Sbjct: 256 G-EGVGPQEYTLLKLKVLEPYPSKLSGLKGKN-IFLVAATLRPETMFGQTNCWVRPDMKY 313
Query: 319 AVVKCSKSGDLYVL---AADKVASVASTLET-TFETISTLSGVDLENGTCSHPLIPDKAS 374
+ + +GD+++ AA ++ T + + L G ++ + S PL K
Sbjct: 314 IGFE-TVNGDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYKVI 372
Query: 375 PLLPANHVTMAKGTGLVHTAPAHGMED 401
+LP + KGTG+V + P+ +D
Sbjct: 373 YVLPMLTIKEDKGTGVVTSVPSDSPDD 399
>gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens]
Length = 593
Score = 34.7 bits (78), Expect = 0.47
Identities = 34/149 (22%), Positives = 58/149 (38%), Gaps = 18/149 (12%)
Query: 117 YANGDPHVGHALNKILKDIANRFHMMNG---SKIHFVPGWDCHGLPIEIKVLSELGREAQ 173
Y N PH+GH + +L D R + G + F G D HGL I+ + + G
Sbjct: 53 YVNAAPHIGHLYSALLADALCRHRRLRGPSTAATRFSTGTDEHGLKIQ-QAAATAGLAPT 111
Query: 174 NLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQMYDK 233
L + + F +A I + FIR T + ++ + + +
Sbjct: 112 ELCDRVSEQFQQLFQEAGI--SCTDFIR------------TTEARHRVAVQHFWGVLKSR 157
Query: 234 GLVYRSYKPVFWSPSSRTALAEAELEYNP 262
GL+Y+ ++ S L EA++ P
Sbjct: 158 GLLYKGVYEGWYCASDECFLPEAKVTQQP 186
Score = 31.2 bits (69), Expect = 5.2
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 16/101 (15%)
Query: 591 VPGQD--ILDIWFDSGTSWSYVLPGPDQR------ADLYLEGKDQL---GGWFQSSLLTS 639
VPG D + +W D+ ++ V+ P+ A ++ GKD L ++ + LL +
Sbjct: 268 VPGDDSQTIYVWLDALVNYLTVIGYPNAEFKSWWPATSHIIGKDILKFHAIYWPAFLLGA 327
Query: 640 VAARKRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHPDVVVN 680
+P + + VH G+KMSKSLGNV+ P +N
Sbjct: 328 ----GMSPPQRICVHSHWT-VCGQKMSKSLGNVVDPRTCLN 363
>gi|14043022 methionyl-tRNA synthetase [Homo sapiens]
Length = 900
Score = 32.0 bits (71), Expect = 3.0
Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 16/110 (14%)
Query: 474 VIRASKQWFINITDIKTAAKELLKKVKFIPGSALNGMVEMMDRRPYW--------CISRQ 525
V+++S+ F+++ ++ +E L + +PGS + + R W CI+R
Sbjct: 443 VVQSSQHLFLDLPKLEKRLEEWLGRT--LPGSDWTPNAQFITRS--WLRDGLKPRCITRD 498
Query: 526 RVWGVPIPVFHHKTKDEYLINSQTTEHIVKLVEQHGSDIW--WTLPPEQL 573
WG P+P+ + K Y+ T ++ + + +D W W PEQ+
Sbjct: 499 LKWGTPVPLEGFEDKVFYVWFDATIGYL--SITANYTDQWERWWKNPEQV 546
Score = 30.4 bits (67), Expect = 8.8
Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 116 PYANGDPHVGHALNKILK-DIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSE 167
PY N PH+G+ + +L D+ R+ + ++ G D +G E K L E
Sbjct: 273 PYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYLCGTDEYGTATETKALEE 325
>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
Length = 2245
Score = 31.6 bits (70), Expect = 3.9
Identities = 31/98 (31%), Positives = 39/98 (39%), Gaps = 7/98 (7%)
Query: 302 WTIPANEAVCYMPE---SKYAVVKCSKSGDLYVLAADKVASVASTLETTFETISTLSGVD 358
+ + VC P + + SKS DL A VAS A + ISTLSG
Sbjct: 335 FVVSVTTTVCSQPPRTAGDSSPMSISKSADL-TSTATVVASSAPGVGKATIPISTLSGNP 393
Query: 359 LENG---TCSHPLIPDKASPLLPANHVTMAKGTGLVHT 393
L+NG +CS P S L N +T G T
Sbjct: 394 LDNGWTLSCSLPSSSVSTSDLKNINSLTRISSAGNTQT 431
>gi|157885806 chromosome 12 open reading frame 51 [Homo sapiens]
Length = 3996
Score = 30.8 bits (68), Expect = 6.7
Identities = 34/110 (30%), Positives = 45/110 (40%), Gaps = 24/110 (21%)
Query: 794 LSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPILPHLAEEVFQHIPYIK 853
L N I ++ L CE R C+ AL+ I FAP LPHL +F HIP I+
Sbjct: 2425 LDNTNLQIHRELLRCEAAL--ARLYCRMALLNI-------FAPKLPHLFTRLF-HIPAIR 2474
Query: 854 E-------------PKSVFRTGWISTSSIWKKPGLEEAVESA-CAMRDSF 889
+ G IS+SSI L+ + S C+ D F
Sbjct: 2475 DITLEHLQLLSNQLLAPPLPDGTISSSSILLAQSLQHCIHSQNCSATDLF 2524
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 30.8 bits (68), Expect = 6.7
Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 12/120 (10%)
Query: 660 EKGEKMSKSL---GNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAIGPSVL 716
++G ++KSL G VI + G++++K PY VL W + DS + +
Sbjct: 271 KEGSNINKSLTTLGLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATV 330
Query: 717 NAARDDISKLRNTLRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQ 776
+ A D+ + +TLR+ + VN V + +++DL ++ +L +Q
Sbjct: 331 SPAADNYDETLSTLRY---------ADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQ 381
>gi|40217847 activating signal cointegrator 1 complex subunit 3-like 1
[Homo sapiens]
Length = 2136
Score = 30.4 bits (67), Expect = 8.8
Identities = 33/138 (23%), Positives = 60/138 (43%), Gaps = 15/138 (10%)
Query: 862 GWISTSSIWKKPGLEEAVESACAMRDSFLGSIPGKNAAEYKVITVIEPGLLFEIIEMLQS 921
GW+S + + L + V A +DS+L +P + K T +F+I+EM +
Sbjct: 1934 GWLSPALAAME--LAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVESVFDIMEM-ED 1990
Query: 922 EETSSTSQLNELMMASESTLLAQEPR-EMTADVIELKG-------KFLINLEGGDIREES 973
EE ++ QL + +A + + P E++ +V++ L+ LE REE
Sbjct: 1991 EERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLE----REEE 2046
Query: 974 SYKVIVMPTTKEKCPRCW 991
++ P +K W
Sbjct: 2047 VTGPVIAPLFPQKREEGW 2064
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 30.4 bits (67), Expect = 8.8
Identities = 35/128 (27%), Positives = 51/128 (39%), Gaps = 24/128 (18%)
Query: 258 LEYNPEHVSRSI------YVKFPLLKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVC 311
+EYN HV S+ VK L + +A LI PA +
Sbjct: 36 VEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELIQ-----------------PAARSQV 78
Query: 312 YMPESKYAVVKCSKSGDLYVLAADKVASVA-STLETTFETISTLSGVDLENGTCSHPLIP 370
E + VV + D VLAAD S+ S L+ F++++ L+G +C L
Sbjct: 79 EATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCE 138
Query: 371 DKASPLLP 378
K + LLP
Sbjct: 139 GKPAALLP 146
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,830,737
Number of Sequences: 37866
Number of extensions: 1852319
Number of successful extensions: 4442
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 4400
Number of HSP's gapped (non-prelim): 26
length of query: 1012
length of database: 18,247,518
effective HSP length: 112
effective length of query: 900
effective length of database: 14,006,526
effective search space: 12605873400
effective search space used: 12605873400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.