BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|45592963 RAS-like, family 11, member A [Homo sapiens] (242 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|45592963 RAS-like, family 11, member A [Homo sapiens] 482 e-136 gi|13027612 RAS-like family 11 member B [Homo sapiens] 239 2e-63 gi|14249704 RAS-like, estrogen-regulated, growth inhibitor [Homo... 131 5e-31 gi|5902050 Ras-like without CAAX 1 [Homo sapiens] 107 1e-23 gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens] 98 6e-21 gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] 97 1e-20 gi|7706095 RAS-like, family 12 protein [Homo sapiens] 97 1e-20 gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] 96 2e-20 gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo ... 95 5e-20 gi|5032041 Ras homolog enriched in brain [Homo sapiens] 94 8e-20 gi|33946329 ras related v-ral simian leukemia viral oncogene hom... 94 1e-19 gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 94 1e-19 gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform... 93 2e-19 gi|4506533 Ras-like without CAAX 2 [Homo sapiens] 92 3e-19 gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] 91 7e-19 gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] 91 7e-19 gi|13376046 RERG/RAS-like [Homo sapiens] 91 7e-19 gi|21703367 Di-Ras2 [Homo sapiens] 90 2e-18 gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens] 89 3e-18 gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Hom... 88 8e-18 gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] 87 1e-17 gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog ... 87 1e-17 gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog is... 87 1e-17 gi|145386506 muscle RAS oncogene homolog [Homo sapiens] 86 3e-17 gi|145386562 muscle RAS oncogene homolog [Homo sapiens] 86 3e-17 gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] 85 5e-17 gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] 85 5e-17 gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapi... 83 2e-16 gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog i... 83 2e-16 gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens] 80 1e-15 >gi|45592963 RAS-like, family 11, member A [Homo sapiens] Length = 242 Score = 482 bits (1240), Expect = e-136 Identities = 242/242 (100%), Positives = 242/242 (100%) Query: 1 MRPLSMSGHFLLAPIPESSSDYLLPKDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNT 60 MRPLSMSGHFLLAPIPESSSDYLLPKDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNT Sbjct: 1 MRPLSMSGHFLLAPIPESSSDYLLPKDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNT 60 Query: 61 GKLYSRLVYVEGDQLSLQIQDTPGGVQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDS 120 GKLYSRLVYVEGDQLSLQIQDTPGGVQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDS Sbjct: 61 GKLYSRLVYVEGDQLSLQIQDTPGGVQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDS 120 Query: 121 YLSIRPLYQHIRKVHPDSKAPVIIVGNKGDLLHARQVQTQDGIQLANELGSLFLEISTSE 180 YLSIRPLYQHIRKVHPDSKAPVIIVGNKGDLLHARQVQTQDGIQLANELGSLFLEISTSE Sbjct: 121 YLSIRPLYQHIRKVHPDSKAPVIIVGNKGDLLHARQVQTQDGIQLANELGSLFLEISTSE 180 Query: 181 NYEDVCDVFQHLCKEVSKMHGLSGERRRASIIPRPRSPNMQDLKRRFKQALSPKVKAPSA 240 NYEDVCDVFQHLCKEVSKMHGLSGERRRASIIPRPRSPNMQDLKRRFKQALSPKVKAPSA Sbjct: 181 NYEDVCDVFQHLCKEVSKMHGLSGERRRASIIPRPRSPNMQDLKRRFKQALSPKVKAPSA 240 Query: 241 LG 242 LG Sbjct: 241 LG 242 >gi|13027612 RAS-like family 11 member B [Homo sapiens] Length = 248 Score = 239 bits (610), Expect = 2e-63 Identities = 117/216 (54%), Positives = 161/216 (74%), Gaps = 3/216 (1%) Query: 28 IKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGVQ 87 +K+AV+GA VGK+A++VRFLTKRFIGDYE N G LY+R V +EG+ L+LQ+QDTPG +Q Sbjct: 34 VKIAVVGASGVGKTALVVRFLTKRFIGDYERNAGNLYTRQVQIEGETLALQVQDTPG-IQ 92 Query: 88 IQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVGN 147 + ++ + L++C++WA+ ++V+SITDY SY I L+QH++++H ++ PV++V N Sbjct: 93 VHENSLSCSEQLNRCIRWADAVVIVFSITDYKSYELISQLHQHVQQLHLGTRLPVVVVAN 152 Query: 148 KGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSKMHGLSG--E 205 K DLLH +QV Q G+QLA+ LG F E+S SENY DV F LCKEVS S E Sbjct: 153 KADLLHIKQVDPQLGLQLASMLGCSFYEVSVSENYNDVYSAFHVLCKEVSHKQQPSSTPE 212 Query: 206 RRRASIIPRPRSPNMQDLKRRFKQALSPKVKAPSAL 241 +RR S+IPRP+SPNMQDLKRRFKQALS KV+ +++ Sbjct: 213 KRRTSLIPRPKSPNMQDLKRRFKQALSAKVRTVTSV 248 >gi|14249704 RAS-like, estrogen-regulated, growth inhibitor [Homo sapiens] Length = 199 Score = 131 bits (330), Expect = 5e-31 Identities = 69/184 (37%), Positives = 108/184 (58%), Gaps = 8/184 (4%) Query: 27 DIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGV 86 ++KLA+ G VGKSA++VRFLTKRFI +Y+P Y ++ + +S++I DT G Sbjct: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQ- 64 Query: 87 QIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVG 146 +D++ + ++W EGF+LVY ITD S+ + PL + ++ +I+VG Sbjct: 65 --EDTIQR-----EGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVG 117 Query: 147 NKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSKMHGLSGER 206 NK DL H+RQV T++G +LA EL F E S ++ ++F LC+EV + + G+ Sbjct: 118 NKADLDHSRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRMVQGKT 177 Query: 207 RRAS 210 RR S Sbjct: 178 RRRS 181 >gi|5902050 Ras-like without CAAX 1 [Homo sapiens] Length = 219 Score = 107 bits (266), Expect = 1e-23 Identities = 64/180 (35%), Positives = 96/180 (53%), Gaps = 8/180 (4%) Query: 19 SSDYLLPKDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQ 78 SS L ++ KL +LGAG VGKSAM ++F++ RF D++P Y + ++ + +L Sbjct: 13 SSPAGLSREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLD 72 Query: 79 IQDTPGGVQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDS 138 I DT G + Q + + EGF++ YSITD S+ +R Q I +V Sbjct: 73 ILDTAGQAEFTAMRDQYMRA-------GEGFIICYSITDRRSFHEVREFKQLIYRVRRTD 125 Query: 139 KAPVIIVGNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSK 198 PV++VGNK DL RQV ++G+ LA E F E S + Y + DVF L +E+ + Sbjct: 126 DTPVVLVGNKSDLKQLRQVTKEEGLALAREFSCPFFETSAAYRYY-IDDVFHALVREIRR 184 >gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens] Length = 183 Score = 98.2 bits (243), Expect = 6e-21 Identities = 58/184 (31%), Positives = 99/184 (53%), Gaps = 8/184 (4%) Query: 29 KLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGVQI 88 K+ +LG VGK+++ +F+ F Y+P YS++V + D+ L + DT G Sbjct: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAG---- 63 Query: 89 QDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVGNK 148 QD + S + G++LVYS+T S+ I LYQ + + H ++ PV++VGNK Sbjct: 64 QDEYSILPYSF---IIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK 120 Query: 149 GDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSKMHGLSGERRR 208 DL R+VQ +G +LA G+ F+E S EN + +F + +E++++ G+ RR Sbjct: 121 ADLSPEREVQAVEGKKLAESWGATFMESSAREN-QLTQGIFTKVIQEIARVENSYGQERR 179 Query: 209 ASII 212 ++ Sbjct: 180 CHLM 183 >gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] Length = 183 Score = 97.4 bits (241), Expect = 1e-20 Identities = 58/172 (33%), Positives = 95/172 (55%), Gaps = 8/172 (4%) Query: 26 KDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGG 85 ++ K+ VLG+G VGKSA+ V+F+T FI Y+P Y + + V+ L+I DT G Sbjct: 2 REYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGT 61 Query: 86 VQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIV 145 Q + + +GF+LVYS+ + S+ I+P+ I +V K PVI+V Sbjct: 62 EQFASMRDLYIKN-------GQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILV 114 Query: 146 GNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVS 197 GNK DL R+V + +G LA E G F+E S +++ V ++F + ++++ Sbjct: 115 GNKVDLESEREVSSSEGRALAEEWGCPFMETS-AKSKTMVDELFAEIVRQMN 165 >gi|7706095 RAS-like, family 12 protein [Homo sapiens] Length = 266 Score = 97.4 bits (241), Expect = 1e-20 Identities = 60/180 (33%), Positives = 90/180 (50%), Gaps = 18/180 (10%) Query: 25 PKDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPG 84 P ++ LA+LG GKSA+ V+FLTKRFI +Y+PN YS V+ + L++ DT Sbjct: 18 PLEVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTAD 77 Query: 85 GVQIQDSLPQVVDSLSKC---VQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVH---PDS 138 +D+ C + WA FL+VYS+ S+ S Y + +H Sbjct: 78 -----------LDTPRNCERYLNWAHAFLVVYSVDSRQSFDS-SSSYLELLALHAKETQR 125 Query: 139 KAPVIIVGNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSK 198 P +++GNK D+ RQV +G+ LA G LF E+S ++E V VF +E + Sbjct: 126 SIPALLLGNKLDMAQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARR 185 >gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] Length = 183 Score = 96.3 bits (238), Expect = 2e-20 Identities = 57/172 (33%), Positives = 95/172 (55%), Gaps = 8/172 (4%) Query: 26 KDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGG 85 ++ K+ VLG+G VGKSA+ V+F+T FI Y+P Y + + V+ L+I DT G Sbjct: 2 REYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGT 61 Query: 86 VQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIV 145 Q + + +GF+LVYS+ + S+ I+P+ I +V K P+I+V Sbjct: 62 EQFASMRDLYIKN-------GQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILV 114 Query: 146 GNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVS 197 GNK DL R+V + +G LA E G F+E S +++ V ++F + ++++ Sbjct: 115 GNKVDLEPEREVMSSEGRALAQEWGCPFMETS-AKSKSMVDELFAEIVRQMN 165 >gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo sapiens] Length = 206 Score = 95.1 bits (235), Expect = 5e-20 Identities = 56/169 (33%), Positives = 97/169 (57%), Gaps = 9/169 (5%) Query: 29 KLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGVQI 88 K+ ++G+G VGKSA+ ++F+ F+ DYEP Y + V ++G+++ + I DT G Sbjct: 16 KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAG---- 71 Query: 89 QDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVH-PDSKAPVIIVGN 147 Q+ + D+ + EGFLLV+SIT+++S+ + + I +V + K P+++VGN Sbjct: 72 QEDYAAIRDNYFRS---GEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGN 128 Query: 148 KGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEV 196 K DL RQV ++ A E G ++E S ++ +V VF L +E+ Sbjct: 129 KSDLEERRQVPVEEARSKAEEWGVQYVETS-AKTRANVDKVFFDLMREI 176 >gi|5032041 Ras homolog enriched in brain [Homo sapiens] Length = 184 Score = 94.4 bits (233), Expect = 8e-20 Identities = 56/180 (31%), Positives = 96/180 (53%), Gaps = 8/180 (4%) Query: 26 KDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGG 85 K K+A+LG VGKS++ ++F+ +F+ Y+P +++L+ V G + LQ+ DT G Sbjct: 5 KSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAG- 63 Query: 86 VQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIV 145 QD + S + G++LVYS+T S+ I+ ++ + + + P+++V Sbjct: 64 ---QDEYSIFPQTYSIDI---NGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLV 117 Query: 146 GNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSKMHGLSGE 205 GNK DL R + ++G LA + FLE S EN + DVF+ + E KM G + + Sbjct: 118 GNKKDLHMERVISYEEGKALAESWNAAFLESSAKEN-QTAVDVFRRIILEAEKMDGAASQ 176 >gi|33946329 ras related v-ral simian leukemia viral oncogene homolog A [Homo sapiens] Length = 206 Score = 94.0 bits (232), Expect = 1e-19 Identities = 60/193 (31%), Positives = 104/193 (53%), Gaps = 13/193 (6%) Query: 29 KLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGVQI 88 K+ ++G+G VGKSA+ ++F+ F+ DYEP Y + V ++G+++ + I DT G Sbjct: 16 KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAG---- 71 Query: 89 QDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVGNK 148 Q+ + D+ + EGFL V+SIT+ +S+ + + I +V D P ++VGNK Sbjct: 72 QEDYAAIRDNYFRS---GEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNK 128 Query: 149 GDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEV--SKMHG---LS 203 DL RQV ++ A + ++E S ++ +V VF L +E+ KM + Sbjct: 129 SDLEDKRQVSVEEAKNRAEQWNVNYVETS-AKTRANVDKVFFDLMREIRARKMEDSKEKN 187 Query: 204 GERRRASIIPRPR 216 G+++R S+ R R Sbjct: 188 GKKKRKSLAKRIR 200 >gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] Length = 183 Score = 93.6 bits (231), Expect = 1e-19 Identities = 56/172 (32%), Positives = 93/172 (54%), Gaps = 8/172 (4%) Query: 26 KDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGG 85 ++ K+ VLG+G VGKSA+ V+F+T FI Y+P Y + + V+ L+I DT G Sbjct: 2 REYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGT 61 Query: 86 VQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIV 145 Q + + +GF+LVYS+ + S+ I+P+ I +V + P+I+V Sbjct: 62 EQFASMRDLYIKN-------GQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILV 114 Query: 146 GNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVS 197 GNK DL R+V +G LA E F+E S ++N V ++F + ++++ Sbjct: 115 GNKVDLEGEREVSYGEGKALAEEWSCPFMETS-AKNKASVDELFAEIVRQMN 165 >gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform a [Homo sapiens] Length = 204 Score = 93.2 bits (230), Expect = 2e-19 Identities = 56/170 (32%), Positives = 88/170 (51%), Gaps = 8/170 (4%) Query: 29 KLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGVQI 88 +L V+G G VGKSA+ ++F+ F+ DY+P Y++ ++ L I DT G + Sbjct: 16 RLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEF 75 Query: 89 QDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVGNK 148 Q + + EGFLLV+S+TD S+ I + I +V + P+I++GNK Sbjct: 76 GAMREQYMRT-------GEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNK 128 Query: 149 GDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSK 198 DL H RQV ++G QLA +L ++E S +V F L + + K Sbjct: 129 ADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRM-NVDQAFHELVRVIRK 177 >gi|4506533 Ras-like without CAAX 2 [Homo sapiens] Length = 217 Score = 92.4 bits (228), Expect = 3e-19 Identities = 61/211 (28%), Positives = 103/211 (48%), Gaps = 23/211 (10%) Query: 26 KDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGG 85 ++ K+ +LGAG VGKSAM ++F++ +F ++P Y V ++ + L I DT G Sbjct: 19 REYKVVMLGAGGVGKSAMTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAGQ 78 Query: 86 VQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIV 145 + Q + + EGF++ YS+TD S+ + I +V + P+++V Sbjct: 79 AEFTAMREQYM-------RGGEGFIICYSVTDRQSFQEAAKFKELIFQVRHTYEIPLVLV 131 Query: 146 GNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSKMHGLSGE 205 GNK DL RQV T++G+ LA E F E S + + + D F L +E+ K + Sbjct: 132 GNKIDLEQFRQVSTEEGLSLAQEYNCGFFETSAALRF-CIDDAFHGLVREIRKKESM--- 187 Query: 206 RRRASIIPRPRSPNMQDLKRRFKQALSPKVK 236 P++ + K + K +L K+K Sbjct: 188 ------------PSLMEKKLKRKDSLWKKLK 206 >gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] Length = 184 Score = 91.3 bits (225), Expect = 7e-19 Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%) Query: 26 KDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGG 85 ++ KL VLG+G VGKSA+ V+F+ F+ Y+P Y + V V+ Q L+I DT G Sbjct: 2 REYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGT 61 Query: 86 VQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIV 145 Q + + +GF LVYSIT ++ ++ L + I +V P+I+V Sbjct: 62 EQFTAMRDLYMKN-------GQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILV 114 Query: 146 GNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSKMHGLSGE 205 GNK DL R V + G LA + + S++++ +V ++F L +++++ + G+ Sbjct: 115 GNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGK 174 Query: 206 RRRAS 210 R+ S Sbjct: 175 ARKKS 179 >gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] Length = 184 Score = 91.3 bits (225), Expect = 7e-19 Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%) Query: 26 KDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGG 85 ++ KL VLG+G VGKSA+ V+F+ F+ Y+P Y + V V+ Q L+I DT G Sbjct: 2 REYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGT 61 Query: 86 VQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIV 145 Q + + +GF LVYSIT ++ ++ L + I +V P+I+V Sbjct: 62 EQFTAMRDLYMKN-------GQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILV 114 Query: 146 GNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSKMHGLSGE 205 GNK DL R V + G LA + + S++++ +V ++F L +++++ + G+ Sbjct: 115 GNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGK 174 Query: 206 RRRAS 210 R+ S Sbjct: 175 ARKKS 179 >gi|13376046 RERG/RAS-like [Homo sapiens] Length = 205 Score = 91.3 bits (225), Expect = 7e-19 Identities = 59/171 (34%), Positives = 92/171 (53%), Gaps = 11/171 (6%) Query: 42 AMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGVQIQDSLPQVVDSLSK 101 A+ VRFLTKRFIG+Y N +Y + + +E QL+L+I D Q + SL+ Sbjct: 19 ALTVRFLTKRFIGEYASNFESIYKKHLCLERKQLNLEIYDPCSQTQ------KAKFSLTS 72 Query: 102 CVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDS-----KAPVIIVGNKGDLLHARQ 156 + WA+GF++VY I+D S+ + L IR+ ++ V +VGNK DL H R+ Sbjct: 73 ELHWADGFVIVYDISDRSSFAFAKALIYRIREPQTSHCKRAVESAVFLVGNKRDLCHVRE 132 Query: 157 VQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSKMHGLSGERR 207 V ++G +LA E F E+S +E +V +F + K++ L +RR Sbjct: 133 VGWEEGQKLALENRCQFCELSAAEQSLEVEMMFIRIIKDILINFKLKEKRR 183 >gi|21703367 Di-Ras2 [Homo sapiens] Length = 199 Score = 90.1 bits (222), Expect = 2e-18 Identities = 60/179 (33%), Positives = 97/179 (54%), Gaps = 15/179 (8%) Query: 15 IPESSSDYLLPKDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQ 74 +PE S+DY ++AV GAG VGKS++++RF+ F Y P Y +++ + Sbjct: 1 MPEQSNDY------RVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSI 54 Query: 75 LSLQIQDTPGGVQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKV 134 +LQI DT G Q + LS + F+LVYSIT S ++P+Y+ I ++ Sbjct: 55 CTLQITDTTGSHQF-----PAMQRLS--ISKGHAFILVYSITSRQSLEELKPIYEQICEI 107 Query: 135 HPDSKA-PVIIVGNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHL 192 D ++ P+++VGNK D +R+VQ+ + LA F+E S N+ +V ++FQ L Sbjct: 108 KGDVESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNH-NVKELFQEL 165 >gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens] Length = 188 Score = 89.0 bits (219), Expect = 3e-18 Identities = 56/172 (32%), Positives = 92/172 (53%), Gaps = 9/172 (5%) Query: 27 DIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGV 86 + KL V+GAG VGKSA+ ++ + F+ +Y+P Y + V ++G+ L I DT G Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG-- 60 Query: 87 QIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVG 146 Q+ + D + ++ EGFL V++I + S+ I + I++V P+++VG Sbjct: 61 --QEEYSAMRD---QYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVG 115 Query: 147 NKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSK 198 NK D L +R V T+ LA G F+E S ++ + V D F L +E+ K Sbjct: 116 NKCD-LPSRTVDTKQAQDLARSYGIPFIETS-AKTRQGVDDAFYTLVREIRK 165 >gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Homo sapiens] Length = 189 Score = 87.8 bits (216), Expect = 8e-18 Identities = 55/170 (32%), Positives = 91/170 (53%), Gaps = 9/170 (5%) Query: 27 DIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGV 86 + KL V+GAG VGKSA+ ++ + F+ +Y+P Y + V ++G+ L I DT G Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG-- 60 Query: 87 QIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVG 146 Q+ + D + ++ EGFL V++I + S+ I + I++V P+++VG Sbjct: 61 --QEEYSAMRD---QYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVG 115 Query: 147 NKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEV 196 NK D L R V T+ +LA G F+E S ++ + V D F L +E+ Sbjct: 116 NKCD-LPTRTVDTKQAHELAKSYGIPFIETS-AKTRQGVEDAFYTLVREI 163 >gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] Length = 189 Score = 87.4 bits (215), Expect = 1e-17 Identities = 58/179 (32%), Positives = 95/179 (53%), Gaps = 15/179 (8%) Query: 27 DIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGV 86 + KL V+GAG VGKSA+ ++ + F+ +Y+P Y + V ++G+ L I DT G Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG-- 60 Query: 87 QIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVG 146 Q+ + D + ++ EGFL V++I + S+ I + I++V P+++VG Sbjct: 61 --QEEYSAMRD---QYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVG 115 Query: 147 NKGDLLHARQVQTQDGIQLANELGSLFLEIS--TSENYED-----VCDVFQHLCKEVSK 198 NK D L +R V T+ LA G F+E S T + ED V ++ Q+ K++SK Sbjct: 116 NKCD-LPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISK 173 >gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog isoform 1 [Homo sapiens] Length = 189 Score = 87.0 bits (214), Expect = 1e-17 Identities = 54/170 (31%), Positives = 92/170 (54%), Gaps = 9/170 (5%) Query: 27 DIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGV 86 + KL V+GAG VGKSA+ ++ + F+ +Y+P Y + V ++G+ L I DT G Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG-- 60 Query: 87 QIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVG 146 Q+ + D + ++ EGFL V++I + S+ I + I++V P+++VG Sbjct: 61 --QEEYSAMRD---QYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVG 115 Query: 147 NKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEV 196 NK DL AR V+++ LA G ++E S ++ + V D F L +E+ Sbjct: 116 NKCDLA-ARTVESRQAQDLARSYGIPYIETS-AKTRQGVEDAFYTLVREI 163 >gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog isoform 1 [Homo sapiens] Length = 189 Score = 87.0 bits (214), Expect = 1e-17 Identities = 54/170 (31%), Positives = 92/170 (54%), Gaps = 9/170 (5%) Query: 27 DIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGV 86 + KL V+GAG VGKSA+ ++ + F+ +Y+P Y + V ++G+ L I DT G Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG-- 60 Query: 87 QIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVG 146 Q+ + D + ++ EGFL V++I + S+ I + I++V P+++VG Sbjct: 61 --QEEYSAMRD---QYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVG 115 Query: 147 NKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEV 196 NK DL AR V+++ LA G ++E S ++ + V D F L +E+ Sbjct: 116 NKCDLA-ARTVESRQAQDLARSYGIPYIETS-AKTRQGVEDAFYTLVREI 163 >gi|145386506 muscle RAS oncogene homolog [Homo sapiens] Length = 208 Score = 85.9 bits (211), Expect = 3e-17 Identities = 50/168 (29%), Positives = 85/168 (50%), Gaps = 7/168 (4%) Query: 29 KLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGVQI 88 KL V+G G VGKSA+ ++F K F+ DY+P Y + ++ L + DT G + Sbjct: 15 KLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEF 74 Query: 89 QDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVGNK 148 Q + + +GFL+VYS+TD S+ + +Q I +V P+I+V NK Sbjct: 75 SAMREQYMRT-------GDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANK 127 Query: 149 GDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEV 196 DL+H R++ + G ++A + ++E S + +V F L + + Sbjct: 128 VDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVI 175 >gi|145386562 muscle RAS oncogene homolog [Homo sapiens] Length = 208 Score = 85.9 bits (211), Expect = 3e-17 Identities = 50/168 (29%), Positives = 85/168 (50%), Gaps = 7/168 (4%) Query: 29 KLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGVQI 88 KL V+G G VGKSA+ ++F K F+ DY+P Y + ++ L + DT G + Sbjct: 15 KLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEF 74 Query: 89 QDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVGNK 148 Q + + +GFL+VYS+TD S+ + +Q I +V P+I+V NK Sbjct: 75 SAMREQYMRT-------GDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANK 127 Query: 149 GDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEV 196 DL+H R++ + G ++A + ++E S + +V F L + + Sbjct: 128 VDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVI 175 >gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] Length = 184 Score = 85.1 bits (209), Expect = 5e-17 Identities = 57/174 (32%), Positives = 93/174 (53%), Gaps = 9/174 (5%) Query: 26 KDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGG 85 ++ KL VLG+G VGKSA+ V+F+ F+ Y+P Y + V V+ Q L+I DT G Sbjct: 2 REYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGT 61 Query: 86 VQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIV 145 Q + + +GF LVYSIT ++ ++ L + I +V P+I+V Sbjct: 62 EQFTAMRDLYMKN-------GQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILV 114 Query: 146 GNKGDLLHARQVQTQDGIQLANE-LGSLFLEISTSENYEDVCDVFQHLCKEVSK 198 GNK DL R V + G LA + FLE S++++ +V ++F L +++++ Sbjct: 115 GNKCDLEDERVVGKEQGQNLARQWCNCAFLE-SSAKSKINVNEIFYDLVRQINR 167 >gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] Length = 184 Score = 85.1 bits (209), Expect = 5e-17 Identities = 57/174 (32%), Positives = 93/174 (53%), Gaps = 9/174 (5%) Query: 26 KDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGG 85 ++ KL VLG+G VGKSA+ V+F+ F+ Y+P Y + V V+ Q L+I DT G Sbjct: 2 REYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGT 61 Query: 86 VQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIV 145 Q + + +GF LVYSIT ++ ++ L + I +V P+I+V Sbjct: 62 EQFTAMRDLYMKN-------GQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILV 114 Query: 146 GNKGDLLHARQVQTQDGIQLANE-LGSLFLEISTSENYEDVCDVFQHLCKEVSK 198 GNK DL R V + G LA + FLE S++++ +V ++F L +++++ Sbjct: 115 GNKCDLEDERVVGKEQGQNLARQWCNCAFLE-SSAKSKINVNEIFYDLVRQINR 167 >gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapiens] Length = 218 Score = 83.2 bits (204), Expect = 2e-16 Identities = 53/170 (31%), Positives = 81/170 (47%), Gaps = 8/170 (4%) Query: 29 KLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGVQI 88 KL V+G G VGKSA+ ++F+ F+ DY+P Y+++ V+G L I DT G + Sbjct: 31 KLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDTAGQEEF 90 Query: 89 QDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVGNK 148 Q + + GFLLV++I D S+ + L+ I +V PV++VGNK Sbjct: 91 GAMREQYMRA-------GHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNK 143 Query: 149 GDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSK 198 DL RQV + + E S +V + F+ L + V K Sbjct: 144 ADLESQRQVPRSEASAFGASHHVAYFEASAKLRL-NVDEAFEQLVRAVRK 192 >gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog isoform 2 [Homo sapiens] Length = 170 Score = 82.8 bits (203), Expect = 2e-16 Identities = 49/151 (32%), Positives = 82/151 (54%), Gaps = 8/151 (5%) Query: 27 DIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGV 86 + KL V+GAG VGKSA+ ++ + F+ +Y+P Y + V ++G+ L I DT G Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG-- 60 Query: 87 QIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVG 146 Q+ + D + ++ EGFL V++I + S+ I + I++V P+++VG Sbjct: 61 --QEEYSAMRD---QYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVG 115 Query: 147 NKGDLLHARQVQTQDGIQLANELGSLFLEIS 177 NK DL AR V+++ LA G ++E S Sbjct: 116 NKCDLA-ARTVESRQAQDLARSYGIPYIETS 145 >gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens] Length = 198 Score = 80.5 bits (197), Expect = 1e-15 Identities = 58/179 (32%), Positives = 92/179 (51%), Gaps = 16/179 (8%) Query: 15 IPESSSDYLLPKDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQ 74 +PE S+DY ++ V GAG VGKS++++RF+ F Y P Y +++ + Sbjct: 1 MPEQSNDY------RVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSV 54 Query: 75 LSLQIQDTPGGVQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKV 134 +LQI DT G Q + LS + F+LV+S+T S + P+Y+ I ++ Sbjct: 55 CTLQITDTTGSHQF-----PAMQRLS--ISKGHAFILVFSVTSKQSLEELGPIYKLIVQI 107 Query: 135 HPD-SKAPVIIVGNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHL 192 PV++VGNK D R+V T++ +A E F+E S NY +V ++FQ L Sbjct: 108 KGSVEDIPVMLVGNKCDETQ-REVDTREAQAVAQEWKCAFMETSAKMNY-NVKELFQEL 164 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.137 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,249,582 Number of Sequences: 37866 Number of extensions: 394465 Number of successful extensions: 1419 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 154 Number of HSP's successfully gapped in prelim test: 55 Number of HSP's that attempted gapping in prelim test: 1109 Number of HSP's gapped (non-prelim): 215 length of query: 242 length of database: 18,247,518 effective HSP length: 99 effective length of query: 143 effective length of database: 14,498,784 effective search space: 2073326112 effective search space used: 2073326112 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.