Guide to the Human Genome
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Search of human proteins with 13129114

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13129114 alpha-1,6-mannosyltransferase ALG12 [Homo sapiens]
         (488 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13129114 alpha-1,6-mannosyltransferase ALG12 [Homo sapiens]        985   0.0  
gi|110224465 phosphatidylinositol glycan, class B [Homo sapiens]       80   5e-15
gi|118026921 asparagine-linked glycosylation 9 protein isoform a...    56   6e-08
gi|118026933 asparagine-linked glycosylation 9 protein isoform b...    56   8e-08
gi|118026937 asparagine-linked glycosylation 9 protein isoform c...    44   4e-04
gi|118026935 asparagine-linked glycosylation 9 protein isoform d...    43   6e-04
gi|120587023 down-regulated in metastasis [Homo sapiens]               30   6.5  
gi|89036565 PREDICTED: similar to Temporarily Assigned Gene name...    30   6.5  
gi|5902084 silver homolog [Homo sapiens]                               30   6.5  

>gi|13129114 alpha-1,6-mannosyltransferase ALG12 [Homo sapiens]
          Length = 488

 Score =  985 bits (2547), Expect = 0.0
 Identities = 488/488 (100%), Positives = 488/488 (100%)

Query: 1   MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEF 60
           MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEF
Sbjct: 1   MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEF 60

Query: 61  PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRR 120
           PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRR
Sbjct: 61  PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRR 120

Query: 121 HFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFAI 180
           HFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFAI
Sbjct: 121 HFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFAI 180

Query: 181 IVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEG 240
           IVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEG
Sbjct: 181 IVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEG 240

Query: 241 KVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPTVLALGFMA 300
           KVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPTVLALGFMA
Sbjct: 241 KVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPTVLALGFMA 300

Query: 301 LYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSA 360
           LYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSA
Sbjct: 301 LYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSA 360

Query: 361 TALYVSHFNYPGGVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDV 420
           TALYVSHFNYPGGVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDV
Sbjct: 361 TALYVSHFNYPGGVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDV 420

Query: 421 QPGTGMLAYTHILMEAAPGLLALYRDTHRVLASVVGTTGVSLNLTQLPPFNVHLQTKLVL 480
           QPGTGMLAYTHILMEAAPGLLALYRDTHRVLASVVGTTGVSLNLTQLPPFNVHLQTKLVL
Sbjct: 421 QPGTGMLAYTHILMEAAPGLLALYRDTHRVLASVVGTTGVSLNLTQLPPFNVHLQTKLVL 480

Query: 481 LERLPRPS 488
           LERLPRPS
Sbjct: 481 LERLPRPS 488


>gi|110224465 phosphatidylinositol glycan, class B [Homo sapiens]
          Length = 554

 Score = 79.7 bits (195), Expect = 5e-15
 Identities = 98/377 (25%), Positives = 160/377 (42%), Gaps = 58/377 (15%)

Query: 6   SSGRRPLLLG--LLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEFP-G 62
           S+ RR  LLG  + + + T+ L I     V+ SF          +WQ LE   H+ F  G
Sbjct: 49  SARRRGDLLGENIYLLLFTIALRILNCFLVQTSFVPDE------YWQSLEVSHHMVFNYG 102

Query: 63  VVP-------RTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIV------RGVLGLGVIF 109
            +        R++  P++ A     ++Y +  L + K   QL++      + +L      
Sbjct: 103 YLTWEWTERLRSYTYPLIFA-----SIYKILHL-LGKDSVQLLIWIPRLAQALLSAVADV 156

Query: 110 GLWTLQKEVRRH------FGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAA 163
            L++L K++         F   + + F W         + CTRTL N +   + ++AL  
Sbjct: 157 RLYSLMKQLENQEVARWVFFCQLCSWFTW---------YCCTRTLTNTMETVLTIIALFY 207

Query: 164 WLRH-----EWARFIWLSAFAIIVFRVELCLFLGLLLL-LALGNRKVSVVRALRHAVPAG 217
           +           ++  L A A I+    + L+  LL        RK+ ++  L H +P G
Sbjct: 208 YPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLI--LHHFLPVG 265

Query: 218 ILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLL 277
            + L L++ +D  F+ Q T  +   L +N + N  + +G+ P  WYF    P  LG  L 
Sbjct: 266 FVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGTFYGSHPWHWYFSQGFPVILGTHLP 325

Query: 278 FIPLG--LVDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNY 335
           F   G  L  +R     V  L  + +YS+L HKE RFI    P   +     C Y L  +
Sbjct: 326 FFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVF----CGYSL-TH 380

Query: 336 KKSWLYKAGSLLVIGHL 352
            K+W   A S L + +L
Sbjct: 381 LKTWKKPALSFLFLSNL 397


>gi|118026921 asparagine-linked glycosylation 9 protein isoform a
           [Homo sapiens]
          Length = 618

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 84/363 (23%), Positives = 148/363 (40%), Gaps = 52/363 (14%)

Query: 2   AGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNL-QATHDLLYHWQDLEQYDHLEF 60
           A +GS+  + LL   L A    ++  C     +E+FN  + TH L+Y     E +   E+
Sbjct: 55  APEGSTAFKCLLSARLCAALLSNISDC-----DETFNYWEPTHYLIYG----EGFQTWEY 105

Query: 61  -PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVR 119
            P    R++     + + + PA +   +L+ +K      +R +L            K V 
Sbjct: 106 SPAYAIRSY---AYLLLHAWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVC 162

Query: 120 RHFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFA 179
           + FG  V+ M      +   +    +  LP+   +   L+A+  W         ++   +
Sbjct: 163 KKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTLIAMTGW---------YMDKTS 213

Query: 180 IIVFRVELCLFLGLLLLLALGNRKVSVVRALRH--------AVPAGILCLGLTVAVDSYF 231
           I V  V     LG     ALG      +  ++H        ++ A IL L   V +DSY+
Sbjct: 214 IAVLGVAAGAILGWPFSAALGLPIAFDLLVMKHRWKSFFHWSLMALILFLVPVVVIDSYY 273

Query: 232 WRQLTWPEGKVLWYNTVLNKSSN-WGTSPLLWYFYSA-----LPRGLGCSLLFIPL-GLV 284
           + +L      ++ YN       + +GT P  WYFY              +LL +PL  L+
Sbjct: 274 YGKLVIAPLNIVLYNVFTPHGPDLYGTEP--WYFYLINGFLNFNVAFALALLVLPLTSLM 331

Query: 285 D---RRTHA-----PTVLALGFMALYSLL----PHKELRFIIYAFPMLNITAARGCSYLL 332
           +   +R H      P  L L  M ++ ++    PHKE RF+   +P++ +  A   S L 
Sbjct: 332 EYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICLCGAVALSALQ 391

Query: 333 NNY 335
           +++
Sbjct: 392 HSF 394


>gi|118026933 asparagine-linked glycosylation 9 protein isoform b
           [Homo sapiens]
          Length = 611

 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 85/363 (23%), Positives = 146/363 (40%), Gaps = 52/363 (14%)

Query: 2   AGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNL-QATHDLLYHWQDLEQYDHLEF 60
           A +GS+  + LL   L A    ++  C     +E+FN  + TH L+Y     E +   E+
Sbjct: 55  APEGSTAFKCLLSARLCAALLSNISDC-----DETFNYWEPTHYLIYG----EGFQTWEY 105

Query: 61  -PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVR 119
            P    R++     + + + PA +   +L+ +K      +R +L            K V 
Sbjct: 106 SPAYAIRSY---AYLLLHAWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVC 162

Query: 120 RHFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFA 179
           + FG  V+ M      +   +    +  LP+   +   L+A+  W         ++   +
Sbjct: 163 KKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTLIAMTGW---------YMDKTS 213

Query: 180 IIVFRVELCLFLGLLLLLALGNRKVSVVRALRH--------AVPAGILCLGLTVAVDSYF 231
           I V  V     LG     ALG      +  ++H        ++ A IL L   V +DSY+
Sbjct: 214 IAVLGVAAGAILGWPFSAALGLPIAFDLLVMKHRWKSFFHWSLMALILFLVPVVVIDSYY 273

Query: 232 WRQLTWPEGKVLWYNTVLNKSSN-WGTSPLLWYFYSA-----LPRGLGCSLLFIPL-GLV 284
           + +L      ++ YN       + +GT P  WYFY              +LL +PL  L+
Sbjct: 274 YGKLVIAPLNIVLYNVFTPHGPDLYGTEP--WYFYLINGFLNFNVAFALALLVLPLTSLM 331

Query: 285 D---RRTHA-----PTVLALGFMALYSLL----PHKELRFIIYAFPMLNITAARGCSYLL 332
           +   +R H      P  L L  M ++ ++    PHKE RF+   +P++ +  A   S L 
Sbjct: 332 EYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICLCGAVALSALQ 391

Query: 333 NNY 335
             Y
Sbjct: 392 KCY 394


>gi|118026937 asparagine-linked glycosylation 9 protein isoform c
           [Homo sapiens]
          Length = 447

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 53/215 (24%), Positives = 90/215 (41%), Gaps = 38/215 (17%)

Query: 148 LPNVLALPVVLLALAAWLRHEWARFIWLSAFAIIVFRVELCLFLGLLLLLALGNRKVSVV 207
           LP+   +   L+A+  W         ++   +I V  V     LG     ALG      +
Sbjct: 20  LPSSFCMYTTLIAMTGW---------YMDKTSIAVLGVAAGAILGWPFSAALGLPIAFDL 70

Query: 208 RALRH--------AVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSN-WGTS 258
             ++H        ++ A IL L   V +DSY++ +L      ++ YN       + +GT 
Sbjct: 71  LVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTE 130

Query: 259 PLLWYFYSA-----LPRGLGCSLLFIPL-GLVD---RRTHA-----PTVLALGFMALYSL 304
           P  WYFY              +LL +PL  L++   +R H      P  L L  M ++ +
Sbjct: 131 P--WYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFI 188

Query: 305 L----PHKELRFIIYAFPMLNITAARGCSYLLNNY 335
           +    PHKE RF+   +P++ +  A   S L +++
Sbjct: 189 IFFIQPHKEERFLFPVYPLICLCGAVALSALQHSF 223


>gi|118026935 asparagine-linked glycosylation 9 protein isoform d
           [Homo sapiens]
          Length = 440

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 54/215 (25%), Positives = 88/215 (40%), Gaps = 38/215 (17%)

Query: 148 LPNVLALPVVLLALAAWLRHEWARFIWLSAFAIIVFRVELCLFLGLLLLLALGNRKVSVV 207
           LP+   +   L+A+  W         ++   +I V  V     LG     ALG      +
Sbjct: 20  LPSSFCMYTTLIAMTGW---------YMDKTSIAVLGVAAGAILGWPFSAALGLPIAFDL 70

Query: 208 RALRH--------AVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSN-WGTS 258
             ++H        ++ A IL L   V +DSY++ +L      ++ YN       + +GT 
Sbjct: 71  LVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTE 130

Query: 259 PLLWYFYSA-----LPRGLGCSLLFIPL-GLVD---RRTHA-----PTVLALGFMALYSL 304
           P  WYFY              +LL +PL  L++   +R H      P  L L  M ++ +
Sbjct: 131 P--WYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFI 188

Query: 305 L----PHKELRFIIYAFPMLNITAARGCSYLLNNY 335
           +    PHKE RF+   +P++ +  A   S L   Y
Sbjct: 189 IFFIQPHKEERFLFPVYPLICLCGAVALSALQKCY 223


>gi|120587023 down-regulated in metastasis [Homo sapiens]
          Length = 2785

 Score = 29.6 bits (65), Expect = 6.5
 Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 17/130 (13%)

Query: 202  RKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYN-----TVLNKSSNWG 256
            RKVS +     + PA + C  + +    Y    L +P G  L  N       LN     G
Sbjct: 2246 RKVSKLAVSAQSEPARVQCRQVFL---KYI---LDYPLGDKLRPNLEFMLAQLNYEHETG 2299

Query: 257  ---TSPLLWYFYSALPRGL---GCSLLFIPLGLVDRRTHAPTVLALGFMALYSLLPHKEL 310
               T  ++ Y +   P+GL    C + FIPL L+     + T   +  M + SLL    L
Sbjct: 2300 RESTLEMIAYLFDTFPQGLLHENCGMFFIPLCLMTINDDSATCKKMASMTIKSLLGKISL 2359

Query: 311  RFIIYAFPML 320
                + F M+
Sbjct: 2360 EKKDWLFDMV 2369


>gi|89036565 PREDICTED: similar to Temporarily Assigned Gene name
            family member (tag-184) [Homo sapiens]
          Length = 2785

 Score = 29.6 bits (65), Expect = 6.5
 Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 17/130 (13%)

Query: 202  RKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYN-----TVLNKSSNWG 256
            RKVS +     + PA + C  + +    Y    L +P G  L  N       LN     G
Sbjct: 2246 RKVSKLAVSAQSEPARVQCRQVFL---KYI---LDYPLGDKLRPNLEFMLAQLNYEHETG 2299

Query: 257  ---TSPLLWYFYSALPRGL---GCSLLFIPLGLVDRRTHAPTVLALGFMALYSLLPHKEL 310
               T  ++ Y +   P+GL    C + FIPL L+     + T   +  M + SLL    L
Sbjct: 2300 RESTLEMIAYLFDTFPQGLLHENCGMFFIPLCLMTINDDSATCKKMASMTIKSLLGKISL 2359

Query: 311  RFIIYAFPML 320
                + F M+
Sbjct: 2360 EKKDWLFDMV 2369


>gi|5902084 silver homolog [Homo sapiens]
          Length = 661

 Score = 29.6 bits (65), Expect = 6.5
 Identities = 12/28 (42%), Positives = 18/28 (64%), Gaps = 1/28 (3%)

Query: 234 QLTWPEGKVLWYN-TVLNKSSNWGTSPL 260
           Q   P+G+V+W N T++N S  WG  P+
Sbjct: 94  QKVLPDGQVIWVNNTIINGSQVWGGQPV 121


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.141    0.448 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,425,703
Number of Sequences: 37866
Number of extensions: 774095
Number of successful extensions: 1819
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1804
Number of HSP's gapped (non-prelim): 9
length of query: 488
length of database: 18,247,518
effective HSP length: 106
effective length of query: 382
effective length of database: 14,233,722
effective search space: 5437281804
effective search space used: 5437281804
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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