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Search of human proteins with 109148550
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109148550 N-acylethanolamine acid amidase isoform 1
precursor [Homo sapiens]
(359 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109148550 N-acylethanolamine acid amidase isoform 1 precursor... 733 0.0
gi|109148548 N-acylethanolamine acid amidase isoform 2 precursor... 661 0.0
gi|189011548 N-acylsphingosine amidohydrolase 1 isoform a prepro... 191 1e-48
gi|189011546 N-acylsphingosine amidohydrolase 1 isoform b [Homo ... 191 1e-48
gi|189011550 N-acylsphingosine amidohydrolase 1 isoform c [Homo ... 183 2e-46
gi|156105693 PPAR-alpha interacting complex protein 285 isoform ... 30 2.6
gi|156105695 PPAR-alpha interacting complex protein 285 isoform ... 30 2.6
gi|21362070 hypothetical protein LOC79034 [Homo sapiens] 30 3.3
gi|38348304 von Willebrand factor A domain containing 2 [Homo sa... 30 4.4
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens] 28 9.7
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens] 28 9.7
gi|31377697 glycosyltransferase 25 domain containing 1 [Homo sap... 28 9.7
>gi|109148550 N-acylethanolamine acid amidase isoform 1 precursor
[Homo sapiens]
Length = 359
Score = 733 bits (1891), Expect = 0.0
Identities = 359/359 (100%), Positives = 359/359 (100%)
Query: 1 MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLV 60
MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLV
Sbjct: 1 MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLV 60
Query: 61 RAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAY 120
RAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAY
Sbjct: 61 RAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAY 120
Query: 121 ESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGL 180
ESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGL
Sbjct: 121 ESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGL 180
Query: 181 WTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKT 240
WTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKT
Sbjct: 181 WTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKT 240
Query: 241 PLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDR 300
PLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDR
Sbjct: 241 PLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDR 300
Query: 301 RTSAIKALNATGQANLSLEALFQILSVVPVYNNFTIYTTVMSAGSPDKYMTRIRNPSRK 359
RTSAIKALNATGQANLSLEALFQILSVVPVYNNFTIYTTVMSAGSPDKYMTRIRNPSRK
Sbjct: 301 RTSAIKALNATGQANLSLEALFQILSVVPVYNNFTIYTTVMSAGSPDKYMTRIRNPSRK 359
>gi|109148548 N-acylethanolamine acid amidase isoform 2 precursor
[Homo sapiens]
Length = 323
Score = 661 bits (1706), Expect = 0.0
Identities = 323/323 (100%), Positives = 323/323 (100%)
Query: 1 MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLV 60
MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLV
Sbjct: 1 MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLV 60
Query: 61 RAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAY 120
RAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAY
Sbjct: 61 RAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAY 120
Query: 121 ESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGL 180
ESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGL
Sbjct: 121 ESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGL 180
Query: 181 WTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKT 240
WTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKT
Sbjct: 181 WTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKT 240
Query: 241 PLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDR 300
PLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDR
Sbjct: 241 PLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDR 300
Query: 301 RTSAIKALNATGQANLSLEALFQ 323
RTSAIKALNATGQANLSLEALFQ
Sbjct: 301 RTSAIKALNATGQANLSLEALFQ 323
>gi|189011548 N-acylsphingosine amidohydrolase 1 isoform a
preproprotein [Homo sapiens]
Length = 395
Score = 191 bits (484), Expect = 1e-48
Identities = 116/352 (32%), Positives = 186/352 (52%), Gaps = 33/352 (9%)
Query: 32 AAPRFNVSLDSVPELRWLPVLRHYDLDLVRAAMAQVIGDRVPKWVHVLI--GKVVLELER 89
A P + ++LD P RW ++L L +A + +VI + + ++ + GK++ ++
Sbjct: 46 AVPWYTINLDLPPYKRW------HELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDE 99
Query: 90 FLPQ-------PFTGEIRGMCDFMNLSLADCLLVNLAYESSVFCTSIVAQDSRGHIYHGR 142
LP PF E++G+ ++ L + + N+ YE CTSIVA+D +GH+ HGR
Sbjct: 100 KLPGLLGNFPGPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGR 159
Query: 143 NLDYP-------------FGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPHKF 189
N+D+ L+ LTV++ F +N + F ++F GYVG+ TG P F
Sbjct: 160 NMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLF 219
Query: 190 TVSGDERDK--GWWWENAIAALFRRHIP-VSWLIRATLSESENFEAAVGKLAKTPLIADV 246
+++ +ER G + L ++ + + +L R L S ++E A L KT ++A
Sbjct: 220 SLTLNERFSINGGYLGILEWILGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPA 279
Query: 247 YYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIK 306
Y+I+GG EG VITR+R D++ LD G W+ V+TNYD WK DDRRT A
Sbjct: 280 YFILGGNQSGEGCVITRDRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKM 339
Query: 307 ALNATGQANLSLEALFQILSVVPVYNNFTIYTTV--MSAGSPDKYMTRIRNP 356
LN T Q N+S E ++ +LS PV N T+YTT+ ++ G + Y+ +P
Sbjct: 340 CLNRTSQENISFETMYDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDP 391
>gi|189011546 N-acylsphingosine amidohydrolase 1 isoform b [Homo
sapiens]
Length = 411
Score = 191 bits (484), Expect = 1e-48
Identities = 116/352 (32%), Positives = 186/352 (52%), Gaps = 33/352 (9%)
Query: 32 AAPRFNVSLDSVPELRWLPVLRHYDLDLVRAAMAQVIGDRVPKWVHVLI--GKVVLELER 89
A P + ++LD P RW ++L L +A + +VI + + ++ + GK++ ++
Sbjct: 62 AVPWYTINLDLPPYKRW------HELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDE 115
Query: 90 FLPQ-------PFTGEIRGMCDFMNLSLADCLLVNLAYESSVFCTSIVAQDSRGHIYHGR 142
LP PF E++G+ ++ L + + N+ YE CTSIVA+D +GH+ HGR
Sbjct: 116 KLPGLLGNFPGPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGR 175
Query: 143 NLDYP-------------FGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPHKF 189
N+D+ L+ LTV++ F +N + F ++F GYVG+ TG P F
Sbjct: 176 NMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLF 235
Query: 190 TVSGDERDK--GWWWENAIAALFRRHIP-VSWLIRATLSESENFEAAVGKLAKTPLIADV 246
+++ +ER G + L ++ + + +L R L S ++E A L KT ++A
Sbjct: 236 SLTLNERFSINGGYLGILEWILGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPA 295
Query: 247 YYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIK 306
Y+I+GG EG VITR+R D++ LD G W+ V+TNYD WK DDRRT A
Sbjct: 296 YFILGGNQSGEGCVITRDRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKM 355
Query: 307 ALNATGQANLSLEALFQILSVVPVYNNFTIYTTV--MSAGSPDKYMTRIRNP 356
LN T Q N+S E ++ +LS PV N T+YTT+ ++ G + Y+ +P
Sbjct: 356 CLNRTSQENISFETMYDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDP 407
>gi|189011550 N-acylsphingosine amidohydrolase 1 isoform c [Homo
sapiens]
Length = 389
Score = 183 bits (465), Expect = 2e-46
Identities = 112/343 (32%), Positives = 175/343 (51%), Gaps = 44/343 (12%)
Query: 32 AAPRFNVSLDSVPELRWLPVLRHYDLDLVRAAMAQVIGDRVPKWVHVLIGKVVLELERFL 91
A P + ++LD P RW ++L L +A + ++G+
Sbjct: 69 AVPWYTINLDLPPYKRW------HELMLDKAPVPGLLGN--------------------F 102
Query: 92 PQPFTGEIRGMCDFMNLSLADCLLVNLAYESSVFCTSIVAQDSRGHIYHGRNLDYP---- 147
P PF E++G+ ++ L + + N+ YE CTSIVA+D +GH+ HGRN+D+
Sbjct: 103 PGPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLG 162
Query: 148 ---------FGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDERDK 198
L+ LTV++ F +N + F ++F GYVG+ TG P F+++ +ER
Sbjct: 163 WNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFS 222
Query: 199 --GWWWENAIAALFRRHIP-VSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSP 255
G + L ++ + + +L R L S ++E A L KT ++A Y+I+GG
Sbjct: 223 INGGYLGILEWILGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQS 282
Query: 256 REGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIKALNATGQAN 315
EG VITR+R D++ LD G W+ V+TNYD WK DDRRT A LN T Q N
Sbjct: 283 GEGCVITRDRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQEN 342
Query: 316 LSLEALFQILSVVPVYNNFTIYTTV--MSAGSPDKYMTRIRNP 356
+S E ++ +LS PV N T+YTT+ ++ G + Y+ +P
Sbjct: 343 ISFETMYDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDP 385
>gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1
[Homo sapiens]
Length = 2649
Score = 30.4 bits (67), Expect = 2.6
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 2/61 (3%)
Query: 215 PVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADIWPL 274
P S I AT +++E A G K ++ G + GV T D AD WP
Sbjct: 1007 PASRDITATTAQTEAAAAPAGDAVKEDVVPGA--CAAGAAAAAGVESTEAEDAEADFWPW 1064
Query: 275 D 275
D
Sbjct: 1065 D 1065
>gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2
[Homo sapiens]
Length = 2080
Score = 30.4 bits (67), Expect = 2.6
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 2/61 (3%)
Query: 215 PVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADIWPL 274
P S I AT +++E A G K ++ G + GV T D AD WP
Sbjct: 438 PASRDITATTAQTEAAAAPAGDAVKEDVVPGA--CAAGAAAAAGVESTEAEDAEADFWPW 495
Query: 275 D 275
D
Sbjct: 496 D 496
>gi|21362070 hypothetical protein LOC79034 [Homo sapiens]
Length = 449
Score = 30.0 bits (66), Expect = 3.3
Identities = 15/40 (37%), Positives = 22/40 (55%)
Query: 288 YDHWKPAPKEDDRRTSAIKALNATGQANLSLEALFQILSV 327
+DH P +E +R + LNA+ + LSL+ L Q L V
Sbjct: 319 FDHMVPLVEEINRLADELNPLNASQEIELSLDRLAQALQV 358
>gi|38348304 von Willebrand factor A domain containing 2 [Homo
sapiens]
Length = 725
Score = 29.6 bits (65), Expect = 4.4
Identities = 13/30 (43%), Positives = 18/30 (60%)
Query: 3 TADREARPGLPSLLLLLLAGAGLSAASPPA 32
T R ARPG+P +++L G G A+ PA
Sbjct: 623 TVQRGARPGVPKAVVVLTGGRGAEDAAVPA 652
>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
Length = 641
Score = 28.5 bits (62), Expect = 9.7
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 216 VSWLIRATLSESENFEAAVGKLAK--TPLIADVYYIVGGTSP 255
+SWL TL+E + FE +L + P+I+ +Y GG P
Sbjct: 578 ISWLDANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGP 619
>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
Length = 641
Score = 28.5 bits (62), Expect = 9.7
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 216 VSWLIRATLSESENFEAAVGKLAK--TPLIADVYYIVGGTSP 255
+SWL TL+E + FE +L + P+I+ +Y GG P
Sbjct: 578 ISWLDANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGP 619
>gi|31377697 glycosyltransferase 25 domain containing 1 [Homo
sapiens]
Length = 622
Score = 28.5 bits (62), Expect = 9.7
Identities = 18/42 (42%), Positives = 20/42 (47%), Gaps = 6/42 (14%)
Query: 9 RPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLP 50
R G P L LLLL A L +PP A + PE RW P
Sbjct: 10 RRGQPLLALLLLLLAPLPPGAPPGADAY------FPEERWSP 45
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,771,912
Number of Sequences: 37866
Number of extensions: 605999
Number of successful extensions: 1414
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1401
Number of HSP's gapped (non-prelim): 12
length of query: 359
length of database: 18,247,518
effective HSP length: 103
effective length of query: 256
effective length of database: 14,347,320
effective search space: 3672913920
effective search space used: 3672913920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.