Search of human proteins with 4557737

Search of human proteins with 4557737

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557737 methionine adenosyltransferase I, alpha [Homo
sapiens]
         (395 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557737 methionine adenosyltransferase I, alpha [Homo sapiens]     804   0.0  
gi|5174529 methionine adenosyltransferase II, alpha [Homo sapiens]    699   0.0  
gi|58801559 complement component 1, q subcomponent-like 3 [Homo ...    31   2.2  
gi|21361759 myotubularin related protein 8 [Homo sapiens]              30   2.9  
gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo s...    30   5.0  
gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo s...    30   5.0  
gi|154354972 phosphatase and actin regulator 2 isoform 4 [Homo s...    29   6.5  
gi|154354970 phosphatase and actin regulator 2 isoform 2 [Homo s...    29   6.5  

>gi|4557737 methionine adenosyltransferase I, alpha [Homo sapiens]
          Length = 395

 Score =  804 bits (2076), Expect = 0.0
 Identities = 395/395 (100%), Positives = 395/395 (100%)

Query: 1   MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC 60
           MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC
Sbjct: 1   MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC 60

Query: 61  KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC 120
           KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC
Sbjct: 61  KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC 120

Query: 121 VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS 180
           VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS
Sbjct: 121 VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS 180

Query: 181 KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT 240
           KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT
Sbjct: 181 KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT 240

Query: 241 VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW 300
           VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
Sbjct: 241 VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW 300

Query: 301 VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI 360
           VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI
Sbjct: 301 VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI 360

Query: 361 VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF 395
           VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
Sbjct: 361 VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF 395


>gi|5174529 methionine adenosyltransferase II, alpha [Homo sapiens]
          Length = 395

 Score =  699 bits (1803), Expect = 0.0
 Identities = 333/395 (84%), Positives = 370/395 (93%)

Query: 1   MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC 60
           MNG ++G  +  + EG F+FTSESVGEGHPDKICDQISDAVLDAHL+QDP+AKVACETV 
Sbjct: 1   MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA 60

Query: 61  KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC 120
           KTGM+LL GEITS A VDYQ+VVR+ +KHIGYDDS+KGFD+KTCNVLVALEQQSPDIAQ 
Sbjct: 61  KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG 120

Query: 121 VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS 180
           VHLDRNEED+GAGDQGLMFGYATDETEECMPLTI+LAHKLNA++A+LRR+G LPWLRPDS
Sbjct: 121 VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS 180

Query: 181 KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT 240
           KTQVTVQYMQD GAV+P+R+HTIVISVQH+E++ L+EMR ALKE+VI+AVVPAKYLDEDT
Sbjct: 181 KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT 240

Query: 241 VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW 300
           +YHLQPSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
Sbjct: 241 IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW 300

Query: 301 VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI 360
           VAKSLVK GLCRRVLVQVSYAIGV+ PLSISIF YGTSQK+ERELL++V KNFDLRPGVI
Sbjct: 301 VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI 360

Query: 361 VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF 395
           VRDLDLKKPIYQ+TA YGHFGR  FPWEVP+KL +
Sbjct: 361 VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY 395


>gi|58801559 complement component 1, q subcomponent-like 3 [Homo
           sapiens]
          Length = 255

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 16/44 (36%), Positives = 22/44 (50%)

Query: 254 GPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYA 297
           GP G+ G  GR+ +    G  G +  GA S   Y+ V + A YA
Sbjct: 88  GPPGEKGEPGRQGLPGPPGAPGLNAAGAISAATYSTVPKIAFYA 131


>gi|21361759 myotubularin related protein 8 [Homo sapiens]
          Length = 704

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 1/54 (1%)

Query: 336 GTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEV 389
           G  QK +RE L V  K   + P ++ R  D + P+Y+    YG    S  P+ +
Sbjct: 441 GNCQK-DREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNPSTVPYNI 493


>gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo
           sapiens]
          Length = 634

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 13/82 (15%)

Query: 155 ILAHKLNARMA--DLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIPV-----RIHTIVISV 207
           +L  K++ R +  +L R G+L  L PD    VTV +   NG +IP+     R   +V S 
Sbjct: 61  VLERKISTRQSREELIRRGVLKEL-PDQDGDVTVNFENSNGHMIPIGEESTREENVVKSE 119

Query: 208 QHNEDIT-----LEEMRRALKE 224
           + N  ++     LEE     KE
Sbjct: 120 EGNGSVSEKTPPLEEQAEDKKE 141


>gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo
           sapiens]
          Length = 645

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 13/82 (15%)

Query: 155 ILAHKLNARMA--DLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIPV-----RIHTIVISV 207
           +L  K++ R +  +L R G+L  L PD    VTV +   NG +IP+     R   +V S 
Sbjct: 72  VLERKISTRQSREELIRRGVLKEL-PDQDGDVTVNFENSNGHMIPIGEESTREENVVKSE 130

Query: 208 QHNEDIT-----LEEMRRALKE 224
           + N  ++     LEE     KE
Sbjct: 131 EGNGSVSEKTPPLEEQAEDKKE 152


>gi|154354972 phosphatase and actin regulator 2 isoform 4 [Homo
           sapiens]
          Length = 554

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 10/78 (12%)

Query: 155 ILAHKLNARMA--DLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIPV-----RIHTIVISV 207
           +L  K++ R +  +L R G+L  L PD    VTV +   NG +IP+     R   +V S 
Sbjct: 61  VLERKISTRQSREELIRRGVLKEL-PDQDGDVTVNFENSNGHMIPIGEESTREENVVKSE 119

Query: 208 QHNEDITLEEMRRALKEQ 225
           + N  ++  E    L+EQ
Sbjct: 120 EGNGSVS--EKTPPLEEQ 135


>gi|154354970 phosphatase and actin regulator 2 isoform 2 [Homo
           sapiens]
          Length = 565

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 10/78 (12%)

Query: 155 ILAHKLNARMA--DLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIPV-----RIHTIVISV 207
           +L  K++ R +  +L R G+L  L PD    VTV +   NG +IP+     R   +V S 
Sbjct: 72  VLERKISTRQSREELIRRGVLKEL-PDQDGDVTVNFENSNGHMIPIGEESTREENVVKSE 130

Query: 208 QHNEDITLEEMRRALKEQ 225
           + N  ++  E    L+EQ
Sbjct: 131 EGNGSVS--EKTPPLEEQ 146


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,025,069
Number of Sequences: 37866
Number of extensions: 650817
Number of successful extensions: 1705
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1701
Number of HSP's gapped (non-prelim): 8
length of query: 395
length of database: 18,247,518
effective HSP length: 104
effective length of query: 291
effective length of database: 14,309,454
effective search space: 4164051114
effective search space used: 4164051114
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.