Search of human proteins with 4557655

Search of human proteins with 4557655

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557655 islet amyloid polypeptide precursor [Homo sapiens]
         (89 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557655 islet amyloid polypeptide precursor [Homo sapiens]         177   2e-45
gi|9945304 calcitonin-related polypeptide, beta [Homo sapiens]         46   5e-06
gi|76880478 calcitonin isoform CGRP preproprotein [Homo sapiens]       43   6e-05
gi|38788380 dehydrogenase E1 and transketolase domain containing...    31   0.24 
gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Ho...    27   3.4  
gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Hom...    27   3.4  
gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Ho...    27   3.4  
gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Hom...    27   3.4  
gi|9910392 1-acylglycerol-3-phosphate O-acyltransferase 4 [Homo ...    27   3.4  
gi|63999048 syntaxin binding protein 4 [Homo sapiens]                  27   3.4  
gi|218084958 anoctamin 4 [Homo sapiens]                                26   5.9  

>gi|4557655 islet amyloid polypeptide precursor [Homo sapiens]
          Length = 89

 Score =  177 bits (449), Expect = 2e-45
 Identities = 89/89 (100%), Positives = 89/89 (100%)

Query: 1  MGILKLQVFLIVLSVALNHLKATPIESHQVEKRKCNTATCATQRLANFLVHSSNNFGAIL 60
          MGILKLQVFLIVLSVALNHLKATPIESHQVEKRKCNTATCATQRLANFLVHSSNNFGAIL
Sbjct: 1  MGILKLQVFLIVLSVALNHLKATPIESHQVEKRKCNTATCATQRLANFLVHSSNNFGAIL 60

Query: 61 SSTNVGSNTYGKRNAVEVLKREPLNYLPL 89
          SSTNVGSNTYGKRNAVEVLKREPLNYLPL
Sbjct: 61 SSTNVGSNTYGKRNAVEVLKREPLNYLPL 89


>gi|9945304 calcitonin-related polypeptide, beta [Homo sapiens]
          Length = 127

 Score = 46.2 bits (108), Expect = 5e-06
 Identities = 25/68 (36%), Positives = 35/68 (51%)

Query: 6   LQVFLIVLSVALNHLKATPIESHQVEKRKCNTATCATQRLANFLVHSSNNFGAILSSTNV 65
           +Q ++ + +  L   + T   S   +KR CNTATC T RLA  L  S     +    TNV
Sbjct: 54  VQDYVQMKASELKQEQETQGSSSAAQKRACNTATCVTHRLAGLLSRSGGMVKSNFVPTNV 113

Query: 66  GSNTYGKR 73
           GS  +G+R
Sbjct: 114 GSKAFGRR 121


>gi|76880478 calcitonin isoform CGRP preproprotein [Homo sapiens]
          Length = 128

 Score = 42.7 bits (99), Expect = 6e-05
 Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 8/62 (12%)

Query: 20  LKATPIESHQ--------VEKRKCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTYG 71
           +KA+ +E  Q         +KR C+TATC T RLA  L  S          TNVGS  +G
Sbjct: 61  MKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFG 120

Query: 72  KR 73
           +R
Sbjct: 121 RR 122


>gi|38788380 dehydrogenase E1 and transketolase domain containing 1
           [Homo sapiens]
          Length = 919

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 6/75 (8%)

Query: 18  NHLKATPIESHQ---VEKRKCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTYGKRN 74
           +HL  T ++S     ++  K + AT     L + L   +  F   LS  +VG  T+ +R+
Sbjct: 549 SHLLKTHVQSRMEKMMDGIKLDWATAEALALGSLL---AQGFNVRLSGQDVGRGTFSQRH 605

Query: 75  AVEVLKREPLNYLPL 89
           A+ V +     Y+PL
Sbjct: 606 AIVVCQETDDTYIPL 620


>gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Homo
            sapiens]
          Length = 1221

 Score = 26.9 bits (58), Expect = 3.4
 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 13/42 (30%)

Query: 47   NFLVHSSNNFGAILSSTNVGSN-------------TYGKRNA 75
            N +  SS+N G  LSS+++GSN             TY KRN+
Sbjct: 1148 NIIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSSSTTYFKRNS 1189


>gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Homo
            sapiens]
          Length = 1250

 Score = 26.9 bits (58), Expect = 3.4
 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 13/42 (30%)

Query: 47   NFLVHSSNNFGAILSSTNVGSN-------------TYGKRNA 75
            N +  SS+N G  LSS+++GSN             TY KRN+
Sbjct: 1148 NIIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSSSTTYFKRNS 1189


>gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Homo
            sapiens]
          Length = 1193

 Score = 26.9 bits (58), Expect = 3.4
 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 13/42 (30%)

Query: 47   NFLVHSSNNFGAILSSTNVGSN-------------TYGKRNA 75
            N +  SS+N G  LSS+++GSN             TY KRN+
Sbjct: 1120 NIIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSSSTTYFKRNS 1161


>gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Homo
            sapiens]
          Length = 1222

 Score = 26.9 bits (58), Expect = 3.4
 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 13/42 (30%)

Query: 47   NFLVHSSNNFGAILSSTNVGSN-------------TYGKRNA 75
            N +  SS+N G  LSS+++GSN             TY KRN+
Sbjct: 1120 NIIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSSSTTYFKRNS 1161


>gi|9910392 1-acylglycerol-3-phosphate O-acyltransferase 4 [Homo
          sapiens]
          Length = 378

 Score = 26.9 bits (58), Expect = 3.4
 Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 1/73 (1%)

Query: 10 LIVLSVALNHLKATPIESHQVEKRKCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNT 69
          LI+ ++ L  L   PI      K  C  + C + +L   L   S     I +        
Sbjct: 26 LIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQLVMLLEWWSGTECTIFTDPRAYLK- 84

Query: 70 YGKRNAVEVLKRE 82
          YGK NA+ VL  +
Sbjct: 85 YGKENAIVVLNHK 97


>gi|63999048 syntaxin binding protein 4 [Homo sapiens]
          Length = 553

 Score = 26.9 bits (58), Expect = 3.4
 Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 1/57 (1%)

Query: 13  LSVALNHLKATPI-ESHQVEKRKCNTATCATQRLANFLVHSSNNFGAILSSTNVGSN 68
           L +ALN+L   P  E HQ  +++    +  T    +F+  + N F   L   NVG++
Sbjct: 220 LEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDEVNVGAH 276


>gi|218084958 anoctamin 4 [Homo sapiens]
          Length = 920

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 9/27 (33%), Positives = 17/27 (62%)

Query: 30  VEKRKCNTATCATQRLANFLVHSSNNF 56
           +E+  C TA  + QR+ +F++H+   F
Sbjct: 193 LEENDCYTAPFSQQRIHHFIIHNKETF 219


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.131    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,765,025
Number of Sequences: 37866
Number of extensions: 84134
Number of successful extensions: 163
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 154
Number of HSP's gapped (non-prelim): 11
length of query: 89
length of database: 18,247,518
effective HSP length: 61
effective length of query: 28
effective length of database: 15,937,692
effective search space: 446255376
effective search space used: 446255376
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.