Search of human proteins with 4557421

Search of human proteins with 4557421

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557421 ectonucleoside triphosphate diphosphohydrolase 2
isoform 2 [Homo sapiens]
         (472 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557421 ectonucleoside triphosphate diphosphohydrolase 2 isof...   958   0.0  
gi|45827718 ectonucleoside triphosphate diphosphohydrolase 2 iso...   945   0.0  
gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8 is...   382   e-106
gi|166197702 ectonucleoside triphosphate diphosphohydrolase 3 [H...   369   e-102
gi|110431366 ectonucleoside triphosphate diphosphohydrolase 8 is...   363   e-100
gi|147905700 ectonucleoside triphosphate diphosphohydrolase 1 is...   335   5e-92
gi|45580700 ectonucleoside triphosphate diphosphohydrolase 1 iso...   335   5e-92
gi|193083168 ectonucleoside triphosphate diphosphohydrolase 4 is...   130   2e-30
gi|4758662 ectonucleoside triphosphate diphosphohydrolase 4 isof...   130   3e-30
gi|9966821 ectonucleoside triphosphate diphosphohydrolase 7 [Hom...   124   2e-28
gi|4557427 ectonucleoside triphosphate diphosphohydrolase 5 [Hom...   111   1e-24
gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6 is...    94   3e-19
gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6 is...    94   3e-19
gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo ...    30   6.2  
gi|239743315 PREDICTED: hypothetical protein XP_002342820 [Homo ...    30   6.2  
gi|239508997 PREDICTED: hypothetical protein [Homo sapiens]            30   6.2  
gi|5032105 small optic lobes [Homo sapiens]                            30   6.2  

>gi|4557421 ectonucleoside triphosphate diphosphohydrolase 2 isoform
           2 [Homo sapiens]
          Length = 472

 Score =  958 bits (2476), Expect = 0.0
 Identities = 472/472 (100%), Positives = 472/472 (100%)

Query: 1   MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA 60
           MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA
Sbjct: 1   MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA 60

Query: 61  DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG 120
           DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG
Sbjct: 61  DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG 120

Query: 121 ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF 180
           ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF
Sbjct: 121 ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF 180

Query: 181 IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF 240
           IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF
Sbjct: 181 IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF 240

Query: 241 LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS 300
           LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS
Sbjct: 241 LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS 300

Query: 301 LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG 360
           LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG
Sbjct: 301 LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG 360

Query: 361 LPVATLQQLEAAAVNVCNQTWAQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLN 420
           LPVATLQQLEAAAVNVCNQTWAQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLN
Sbjct: 361 LPVATLQQLEAAAVNVCNQTWAQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLN 420

Query: 421 LTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI 472
           LTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI
Sbjct: 421 LTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI 472


>gi|45827718 ectonucleoside triphosphate diphosphohydrolase 2
           isoform 1 [Homo sapiens]
          Length = 495

 Score =  945 bits (2442), Expect = 0.0
 Identities = 472/495 (95%), Positives = 472/495 (95%), Gaps = 23/495 (4%)

Query: 1   MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA 60
           MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA
Sbjct: 1   MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA 60

Query: 61  DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG 120
           DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG
Sbjct: 61  DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG 120

Query: 121 ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF 180
           ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF
Sbjct: 121 ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF 180

Query: 181 IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF 240
           IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF
Sbjct: 181 IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF 240

Query: 241 LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS 300
           LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS
Sbjct: 241 LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS 300

Query: 301 LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG 360
           LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG
Sbjct: 301 LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG 360

Query: 361 LPVATLQQLEAAAVNVCNQTWA-----------------------QQLLSRGYGFDERAF 397
           LPVATLQQLEAAAVNVCNQTWA                       QQLLSRGYGFDERAF
Sbjct: 361 LPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAF 420

Query: 398 GGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALV 457
           GGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALV
Sbjct: 421 GGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALV 480

Query: 458 LLLRQVHSAKLPSTI 472
           LLLRQVHSAKLPSTI
Sbjct: 481 LLLRQVHSAKLPSTI 495


>gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8
           isoform 1 [Homo sapiens]
          Length = 495

 Score =  382 bits (982), Expect = e-106
 Identities = 204/483 (42%), Positives = 282/483 (58%), Gaps = 37/483 (7%)

Query: 13  LLAAAGLAGL---LLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIV 69
           LL A+G++GL   +LL V    V  P  +K+GIV DAGSSHTS+F+Y+W A+KEN TG+V
Sbjct: 13  LLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVV 72

Query: 70  GQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLN 129
            Q  +C V G GISSY  N + A +SL GCLE+AL  +P+ +H  TP +LGATAGMRLL+
Sbjct: 73  SQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLS 132

Query: 130 LTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRW 189
             N   +  +  AVT  L + P DF GA +L+GQ EG FGW+T NY L   +KY + G W
Sbjct: 133 RKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEW 192

Query: 190 FRPRKGTL-GAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSFLCYGRDQV 248
            +P +  L GA+D+GGASTQITF    P  D++++    LYG  Y VYTHS+LC+GRDQ+
Sbjct: 193 IQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQM 252

Query: 249 LQRLLASALQTHGF----HPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGS 304
           L RLL   +Q+       HPC+  G+ T + LG +Y+SPC  A  P +   +  +++ G+
Sbjct: 253 LSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLSLPQN--LTVEGT 310

Query: 305 SDPHLCRDLVSGLFSFSSCPFSR-CSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMGLPV 363
            +P  C   +  LF+FSSC     C+F+GV+QPP+ G F AFS F+YT  FL  +   P+
Sbjct: 311 GNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFHFLNLTSRQPL 370

Query: 364 ATLQQLEAAAVNVCNQTW-----------------------AQQLLSRGYGFDERAFGGV 400
           +T   + A     C + W                          LL  GYGF E  +  +
Sbjct: 371 ST---VNATIWEFCQRPWKLVEASYPGQDRWLRDYCASGLYILTLLHEGYGFSEETWPSL 427

Query: 401 IFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLL 460
            F+K+A    +GW LGYMLNLT +IPAD P   +   +  WV  ++    AL+A +   L
Sbjct: 428 EFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALVAVVGAAL 487

Query: 461 RQV 463
            Q+
Sbjct: 488 VQL 490


>gi|166197702 ectonucleoside triphosphate diphosphohydrolase 3 [Homo
           sapiens]
          Length = 529

 Score =  369 bits (947), Expect = e-102
 Identities = 194/480 (40%), Positives = 282/480 (58%), Gaps = 36/480 (7%)

Query: 12  LLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQ 71
           LL++   L  + ++ +  ++V  PP LKYGIVLDAGSS T++++Y+WPA+KEN+TG+V Q
Sbjct: 30  LLVSIVVLVSITVIQIHKQEVL-PPGLKYGIVLDAGSSRTTVYVYQWPAEKENNTGVVSQ 88

Query: 72  HSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLT 131
              C V G GISSY +NP    ++   C+++    VP   H  TP++LGATAGMRLL L 
Sbjct: 89  TFKCSVKGSGISSYGNNPQDVPRAFEECMQKVKGQVPSHLHGSTPIHLGATAGMRLLRLQ 148

Query: 132 NPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFR 191
           N  A+  VL ++       PFDFRGA+I+SGQEEGV+GW+TANYL+ NF++      W  
Sbjct: 149 NETAANEVLESIQSYFKSQPFDFRGAQIISGQEEGVYGWITANYLMGNFLEKNLWHMWVH 208

Query: 192 PR-KGTLGAMDLGGASTQITFETTSPAEDRASEV-QLHLYGQHYRVYTHSFLCYGRDQVL 249
           P    T GA+DLGGASTQI+F      +   S++ Q+ LYG  Y +YTHSF CYGR++  
Sbjct: 209 PHGVETTGALDLGGASTQISFVAGEKMDLNTSDIMQVSLYGYVYTLYTHSFQCYGRNEAE 268

Query: 250 QRLLASALQ-----THGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGS 304
           ++ LA  LQ      H  +PC+PR +S    +G V+ S CT+ QRP+++N +  ++  G+
Sbjct: 269 KKFLAMLLQNSPTKNHLTNPCYPRDYSISFTMGHVFDSLCTVDQRPESYNPNDVITFEGT 328

Query: 305 SDPHLCRDLVSGLFSFSSC-PFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMGLPV 363
            DP LC++ V+ +F F +C     CSF+GV+QP + G FVAF+ F+YT   L  S     
Sbjct: 329 GDPSLCKEKVASIFDFKACHDQETCSFDGVYQPKIKGPFVAFAGFYYTASALNLSGSF-- 386

Query: 364 ATLQQLEAAAVNVCNQTWAQ------------------------QLLSRGYGFDERAFGG 399
            +L    ++  N C+Q W+Q                         L   GY F E  +  
Sbjct: 387 -SLDTFNSSTWNFCSQNWSQLPLLLPKFDEVYARSYCFSANYIYHLFVNGYKFTEETWPQ 445

Query: 400 VIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLL 459
           + F+K+  ++++ W+LGYML+LTN IPA+ P +R   +   +V  L  F +A L  L  L
Sbjct: 446 IHFEKEVGNSSIAWSLGYMLSLTNQIPAESPLIRLPIEPPVFVGTLAFFTAAALLCLAFL 505


>gi|110431366 ectonucleoside triphosphate diphosphohydrolase 8
           isoform 2 [Homo sapiens]
          Length = 458

 Score =  363 bits (933), Expect = e-100
 Identities = 196/462 (42%), Positives = 274/462 (59%), Gaps = 32/462 (6%)

Query: 13  LLAAAGLAGL---LLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIV 69
           LL A+G++GL   +LL V    V  P  +K+GIV DAGSSHTS+F+Y+W A+KEN TG+V
Sbjct: 13  LLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVV 72

Query: 70  GQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLN 129
            Q  +C V G GISSY  N + A +SL GCLE+AL  +P+ +H  TP +LGATAGMRLL+
Sbjct: 73  SQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLS 132

Query: 130 LTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRW 189
             N   +  +  AVT  L + P DF GA +L+GQ EG FGW+T NY L   +KY + G W
Sbjct: 133 RKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEW 192

Query: 190 FRPRKGTL-GAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSFLCYGRDQV 248
            +P +  L GA+D+GGASTQITF    P  D++++    LYG  Y VYTHS+LC+GRDQ+
Sbjct: 193 IQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQM 252

Query: 249 LQRLLASALQTHGF----HPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGS 304
           L RLL   +Q+       HPC+  G+ T + LG +Y+SPC  A  P +   +  +++ G+
Sbjct: 253 LSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLSLPQN--LTVEGT 310

Query: 305 SDPHLCRDLVSGLFSFSSCPFSR-CSFNGVFQPPVAGNFVAFSAFFYTVDFLR--TSMGL 361
            +P  C   +  LF+FSSC     C+F+GV+QPP+ G F   +++     +LR   + GL
Sbjct: 311 GNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYVEASYPGQDRWLRDYCASGL 370

Query: 362 PVATLQQLEAAAVNVCNQTWAQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNL 421
            + T                   LL  GYGF E  +  + F+K+A    +GW LGYMLNL
Sbjct: 371 YILT-------------------LLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNL 411

Query: 422 TNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLLRQV 463
           T +IPAD P   +   +  WV  ++    AL+A +   L Q+
Sbjct: 412 TGMIPADAPAQWRAESYGVWVAKVVFMVLALVAVVGAALVQL 453


>gi|147905700 ectonucleoside triphosphate diphosphohydrolase 1
           isoform 2 [Homo sapiens]
          Length = 517

 Score =  335 bits (859), Expect = 5e-92
 Identities = 193/493 (39%), Positives = 275/493 (55%), Gaps = 52/493 (10%)

Query: 7   SLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDT 66
           S++  + L A GL         T++   P  +KYGIVLDAGSSHTS++IYKWPA+KENDT
Sbjct: 32  SIIAVIALLAVGL---------TQNKALPENVKYGIVLDAGSSHTSLYIYKWPAEKENDT 82

Query: 67  GIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMR 126
           G+V Q   C V G GIS +    +     L  C+E+A + +P+ +H  TP+YLGATAGMR
Sbjct: 83  GVVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMR 142

Query: 127 LLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWV 186
           LL + + E +  VL  V  +L+ YPFDF+GARI++GQEEG +GW+T NYLL    K+   
Sbjct: 143 LLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWITINYLLG---KFSQK 199

Query: 187 GRWF------RPRKGTLGAMDLGGASTQITF-ETTSPAEDRASEVQLHLYGQHYRVYTHS 239
            RWF         + T GA+DLGGASTQ+TF       E   + +Q  LYG+ Y VYTHS
Sbjct: 200 TRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNALQFRLYGKDYNVYTHS 259

Query: 240 FLCYGRDQVLQRLLASALQTHGFH----PCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNS 295
           FLCYG+DQ L + LA  +Q         PC+  G+   V + D+Y++PCT  +R +    
Sbjct: 260 FLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCT--KRFEMTLP 317

Query: 296 SARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFL 355
             +  + G  +   C   +  LF+ S CP+S+C+FNG+F PP+ G+F AFSAF++ + FL
Sbjct: 318 FQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGIFLPPLQGDFGAFSAFYFVMKFL 377

Query: 356 RTSMGLPVATLQQLEAAAVNVCNQTWAQ------------------------QLLSRGYG 391
             ++     + +++       C Q W +                         LL +GY 
Sbjct: 378 --NLTSEKVSQEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYCFSGTYILSLLLQGYH 435

Query: 392 FDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASA 451
           F   ++  + F  K   +  GW LGYMLNLTN+IPA+ P L      S++V L++LF+  
Sbjct: 436 FTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQP-LSTPLSHSTYVFLMVLFSLV 494

Query: 452 LLAALVLLLRQVH 464
           L    ++ L   H
Sbjct: 495 LFTVAIIGLLIFH 507


>gi|45580700 ectonucleoside triphosphate diphosphohydrolase 1
           isoform 1 [Homo sapiens]
          Length = 510

 Score =  335 bits (859), Expect = 5e-92
 Identities = 193/493 (39%), Positives = 275/493 (55%), Gaps = 52/493 (10%)

Query: 7   SLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDT 66
           S++  + L A GL         T++   P  +KYGIVLDAGSSHTS++IYKWPA+KENDT
Sbjct: 25  SIIAVIALLAVGL---------TQNKALPENVKYGIVLDAGSSHTSLYIYKWPAEKENDT 75

Query: 67  GIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMR 126
           G+V Q   C V G GIS +    +     L  C+E+A + +P+ +H  TP+YLGATAGMR
Sbjct: 76  GVVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMR 135

Query: 127 LLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWV 186
           LL + + E +  VL  V  +L+ YPFDF+GARI++GQEEG +GW+T NYLL    K+   
Sbjct: 136 LLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWITINYLLG---KFSQK 192

Query: 187 GRWF------RPRKGTLGAMDLGGASTQITF-ETTSPAEDRASEVQLHLYGQHYRVYTHS 239
            RWF         + T GA+DLGGASTQ+TF       E   + +Q  LYG+ Y VYTHS
Sbjct: 193 TRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNALQFRLYGKDYNVYTHS 252

Query: 240 FLCYGRDQVLQRLLASALQTHGFH----PCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNS 295
           FLCYG+DQ L + LA  +Q         PC+  G+   V + D+Y++PCT  +R +    
Sbjct: 253 FLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCT--KRFEMTLP 310

Query: 296 SARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFL 355
             +  + G  +   C   +  LF+ S CP+S+C+FNG+F PP+ G+F AFSAF++ + FL
Sbjct: 311 FQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGIFLPPLQGDFGAFSAFYFVMKFL 370

Query: 356 RTSMGLPVATLQQLEAAAVNVCNQTWAQ------------------------QLLSRGYG 391
             ++     + +++       C Q W +                         LL +GY 
Sbjct: 371 --NLTSEKVSQEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYCFSGTYILSLLLQGYH 428

Query: 392 FDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASA 451
           F   ++  + F  K   +  GW LGYMLNLTN+IPA+ P L      S++V L++LF+  
Sbjct: 429 FTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQP-LSTPLSHSTYVFLMVLFSLV 487

Query: 452 LLAALVLLLRQVH 464
           L    ++ L   H
Sbjct: 488 LFTVAIIGLLIFH 500


>gi|193083168 ectonucleoside triphosphate diphosphohydrolase 4
           isoform b [Homo sapiens]
          Length = 608

 Score =  130 bits (328), Expect = 2e-30
 Identities = 110/384 (28%), Positives = 168/384 (43%), Gaps = 47/384 (12%)

Query: 36  PALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGG--------GISSYAD 87
           P + YGIV+D GSS + +F+Y WP    N   ++      D            GIS +A 
Sbjct: 85  PNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFAT 144

Query: 88  NPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTL 147
           +P   S  +   L  A + VP+ +H  TPLY+  TAGMR+L  +  +A    L+      
Sbjct: 145 SPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLTDIPVH 204

Query: 148 TQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKY-------------GWVGRWFRPRK 194
             + F    A ++SG++EGV+ W+  N++L  F                G        RK
Sbjct: 205 FDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRK 264

Query: 195 GTLGAMDLGGASTQITFE---TTSPAEDRASEVQL----HLYGQHYRVYTHSFLCYG--- 244
            T G +D+GG STQI +E   T   A++  +E  L    H     YRVY  +FL +G   
Sbjct: 265 RTAGILDMGGVSTQIAYEVPKTEEVAKNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNA 324

Query: 245 -RDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSAR-VSLS 302
            R +   R+ A+ +Q +        G  T +     Y  PC           + + + L 
Sbjct: 325 ARQRYEDRIFANTIQKNRL-----LGKQTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLR 379

Query: 303 GSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPV---AGNFVAFSAFFY-TVDFLRTS 358
           G+ D  LCR+ +    + ++   ++ S NGV+QPP+      F  FS F+Y T D LR  
Sbjct: 380 GTGDFDLCRETIQPFMNKTN--ETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDVLRMG 437

Query: 359 MGLPVATLQQLEAAAVNVCNQTWA 382
                A   +   AA + C   W+
Sbjct: 438 GDYNAA---KFTKAAKDYCATKWS 458


>gi|4758662 ectonucleoside triphosphate diphosphohydrolase 4 isoform
           a [Homo sapiens]
          Length = 616

 Score =  130 bits (327), Expect = 3e-30
 Identities = 111/392 (28%), Positives = 169/392 (43%), Gaps = 55/392 (14%)

Query: 36  PALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGG--------GISSYAD 87
           P + YGIV+D GSS + +F+Y WP    N   ++      D            GIS +A 
Sbjct: 85  PNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFAT 144

Query: 88  NPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTL 147
           +P   S  +   L  A + VP+ +H  TPLY+  TAGMR+L  +  +A    L+      
Sbjct: 145 SPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLTDIPVH 204

Query: 148 TQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKY-------------GWVGRWFRPRK 194
             + F    A ++SG++EGV+ W+  N++L  F                G        RK
Sbjct: 205 FDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRK 264

Query: 195 GTLGAMDLGGASTQITFE---TTSPAEDRASEVQLHLYGQH------------YRVYTHS 239
            T G +D+GG STQI +E   T S A  +  EV  +L  +             YRVY  +
Sbjct: 265 RTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYRVYVAT 324

Query: 240 FLCYG----RDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNS 295
           FL +G    R +   R+ A+ +Q +        G  T +     Y  PC           
Sbjct: 325 FLGFGGNAARQRYEDRIFANTIQKNRL-----LGKQTGLTPDMPYLDPCLPLDIKDEIQQ 379

Query: 296 SAR-VSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPV---AGNFVAFSAFFY- 350
           + + + L G+ D  LCR+ +    + ++   ++ S NGV+QPP+      F  FS F+Y 
Sbjct: 380 NGQTIYLRGTGDFDLCRETIQPFMNKTN--ETQTSLNGVYQPPIHFQNSEFYGFSEFYYC 437

Query: 351 TVDFLRTSMGLPVATLQQLEAAAVNVCNQTWA 382
           T D LR       A   +   AA + C   W+
Sbjct: 438 TEDVLRMGGDYNAA---KFTKAAKDYCATKWS 466


>gi|9966821 ectonucleoside triphosphate diphosphohydrolase 7 [Homo
           sapiens]
          Length = 604

 Score =  124 bits (310), Expect = 2e-28
 Identities = 138/501 (27%), Positives = 208/501 (41%), Gaps = 91/501 (18%)

Query: 34  EPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGG--------GISSY 85
           E P L YG+V+D GSS + +F+Y WP    N   ++      D            GIS+ 
Sbjct: 78  EDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKIKPGISAM 137

Query: 86  ADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTH 145
           AD P  AS  L   L  A   VP ++H  TPLY+  TAGMRLL    PE     ++A   
Sbjct: 138 ADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLL----PERKQLAILADLV 193

Query: 146 TLTQYPFDF----RGARILSGQEEGVFGWVTANYLLENF-----IKYGWVGRWFRPRKGT 196
                 FDF      A ++SG++EGV+ W+  N++L  F                 R+ T
Sbjct: 194 KDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEATQELAAGRRRT 253

Query: 197 LGAMDLGGASTQITFETTS-----PA-EDRASEVQLHLYG-----QH----YRVYTHSFL 241
           +G +D+GGAS QI +E  +     PA ++ A+++ L  +      QH    YRVY  +FL
Sbjct: 254 VGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTFL 313

Query: 242 CYGRDQVLQR----LLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSA 297
            +G +   QR    +L   L  +        G  T +   + +  PC           ++
Sbjct: 314 GFGGNFARQRYEDLVLNETLNKNRL-----LGQKTGLSPDNPFLDPCLPVGLTDVVERNS 368

Query: 298 RV-SLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGN---FVAFSAFFY-TV 352
           +V  + G  D   C  ++S L + S+   S+ S NG++Q P+  N   F  FS FFY T 
Sbjct: 369 QVLHVRGRGDWVSCGAMLSPLLARSNT--SQASLNGIYQSPIDFNNSEFYGFSEFFYCTE 426

Query: 353 DFLRTSMGLPVATLQQLEAAAVNVCNQTWA------------------------------ 382
           D LR        T  +   AA + C   W+                              
Sbjct: 427 DVLRIGGRYHGPTFAK---AAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKSAWM 483

Query: 383 QQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIP---ADPPGLRKGTDFS 439
            Q+L  G+ F    +  +   +   D  V W LG +L  T  +P       G+R+     
Sbjct: 484 YQVLHEGFHF-PYDYPNLRTAQLVYDREVQWTLGAILYKTRFLPLRDLRQEGVRQA--HG 540

Query: 440 SWVVLLLLFASALLAALVLLL 460
           SW  L  ++   L  A +L++
Sbjct: 541 SWFRLSFVYNHYLFFACILVV 561


>gi|4557427 ectonucleoside triphosphate diphosphohydrolase 5 [Homo
           sapiens]
          Length = 428

 Score =  111 bits (278), Expect = 1e-24
 Identities = 111/416 (26%), Positives = 168/416 (40%), Gaps = 78/416 (18%)

Query: 40  YGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGC 99
           YGI+ DAGS+ T + +Y +         I+ +    D    G+S++ D P   ++++ G 
Sbjct: 49  YGIMFDAGSTGTRIHVYTFVQKMPGQLPIL-EGEVFDSVKPGLSAFVDQPKQGAETVQGL 107

Query: 100 LEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPE-ASTSVLMAVTHTLTQYPF--DFRG 156
           LE A   +P+     TP+ L ATAG+RLL    PE  + ++L  V     + PF      
Sbjct: 108 LEVAKDSIPRSHWKKTPVVLKATAGLRLL----PEHKAKALLFEVKEIFRKSPFLVPKGS 163

Query: 157 ARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQIT----FE 212
             I+ G +EG+  WVT N+L          G+    R+ T+G +DLGGASTQIT    FE
Sbjct: 164 VSIMDGSDEGILAWVTVNFL---------TGQLHGHRQETVGTLDLGGASTQITFLPQFE 214

Query: 213 TTSPAEDRASEVQLHLYGQHYRVYTHSFLCYG----RDQVLQRLLASALQTHGFH-PCWP 267
            T     R       ++   Y++YTHS+L +G    R   L  L       H F   C P
Sbjct: 215 KTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALETEGTDGHTFRSACLP 274

Query: 268 RGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGSSDPHLCRDLVSGLFSFSSC--PF 325
           R    + + G V                  +    G+ +         G   F  C    
Sbjct: 275 RWLEAEWIFGGV------------------KYQYGGNQE---------GEVGFEPCYAEV 307

Query: 326 SRCSFNGVFQPPVA--GNFVAFSAFF---YTVDFLRTSMGLPVATLQQLEAAAVNVCNQ- 379
            R     + QP     G+F AFS ++      D +    G  +  ++  E  A  VC+  
Sbjct: 308 LRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKG-GILKVEDFERKAREVCDNL 366

Query: 380 --------------TWAQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNL 421
                         ++   LL  G+GF +     +   KK  +   GWALG   +L
Sbjct: 367 ENFTSGSPFLCMDLSYITALLKDGFGFADSTV--LQLTKKVNNIETGWALGATFHL 420


>gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6
           isoform 2 [Homo sapiens]
          Length = 467

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 66/211 (31%), Positives = 103/211 (48%), Gaps = 20/211 (9%)

Query: 40  YGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGC 99
           YGI+ DAGS+ T + ++++         +   H +      G+S+YAD+   ++Q +   
Sbjct: 85  YGIMFDAGSTGTRVHVFQFTRPPRETPTLT--HETFKALKPGLSAYADDVEKSAQGIREL 142

Query: 100 LEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRG--A 157
           L+ A QD+P +    TPL L ATAG+RLL     E +  +L  V       PF       
Sbjct: 143 LDVAKQDIPFDFWKATPLVLKATAGLRLL---PGEKAQKLLQKVKEVFKASPFLVGDDCV 199

Query: 158 RILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQITF----ET 213
            I++G +EGV  W+T N+L          G    P   ++G +DLGG STQI F    E 
Sbjct: 200 SIMNGTDEGVSAWITINFL---------TGSLKTPGGSSVGMLDLGGGSTQIAFLPRVEG 250

Query: 214 TSPAEDRASEVQLHLYGQHYRVYTHSFLCYG 244
           T  A        L ++ + Y++Y++S+L  G
Sbjct: 251 TLQASPPGYLTALRMFNRTYKLYSYSYLGLG 281


>gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6
           isoform 1 [Homo sapiens]
          Length = 484

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 66/211 (31%), Positives = 103/211 (48%), Gaps = 20/211 (9%)

Query: 40  YGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGC 99
           YGI+ DAGS+ T + ++++         +   H +      G+S+YAD+   ++Q +   
Sbjct: 102 YGIMFDAGSTGTRVHVFQFTRPPRETPTLT--HETFKALKPGLSAYADDVEKSAQGIREL 159

Query: 100 LEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRG--A 157
           L+ A QD+P +    TPL L ATAG+RLL     E +  +L  V       PF       
Sbjct: 160 LDVAKQDIPFDFWKATPLVLKATAGLRLL---PGEKAQKLLQKVKEVFKASPFLVGDDCV 216

Query: 158 RILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQITF----ET 213
            I++G +EGV  W+T N+L          G    P   ++G +DLGG STQI F    E 
Sbjct: 217 SIMNGTDEGVSAWITINFL---------TGSLKTPGGSSVGMLDLGGGSTQIAFLPRVEG 267

Query: 214 TSPAEDRASEVQLHLYGQHYRVYTHSFLCYG 244
           T  A        L ++ + Y++Y++S+L  G
Sbjct: 268 TLQASPPGYLTALRMFNRTYKLYSYSYLGLG 298


>gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo
           sapiens]
          Length = 870

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 2/67 (2%)

Query: 277 GDVYQSPCTMAQRPQNFNSSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQP 336
           G VY +  ++ Q   +  S    +  GS   HLC  L++GL S   CP S C    ++  
Sbjct: 165 GPVYTTSPSLHQGEPSLVSEFTAASQGSVR-HLC-SLLAGLSSLFRCPISSCYTLSLYNT 222

Query: 337 PVAGNFV 343
            ++G+ +
Sbjct: 223 SISGSLL 229


>gi|239743315 PREDICTED: hypothetical protein XP_002342820 [Homo
           sapiens]
          Length = 248

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 15/110 (13%)

Query: 28  PTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVP--------- 78
           P R V    +++  + L+AG S    F   W A  + + G  G      +P         
Sbjct: 15  PWRTVGCSGSIQASLALEAGVSMLPTF---WTAWSQQEQGAAGAGVRVALPQVEELGRHD 71

Query: 79  GGGISSYADNPSGASQSLV--GCLEQALQDVPKERHAGTPLYLGATAGMR 126
           GGG  + A       +  +  GC  +A   VP+ R  G+PL LG+    R
Sbjct: 72  GGGEEAQAQEAGDGDERYILEGC-GRARAGVPQTRAPGSPLPLGSVPDPR 120


>gi|239508997 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 15/110 (13%)

Query: 28  PTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVP--------- 78
           P R V    +++  + L+AG S    F   W A  + + G  G      +P         
Sbjct: 15  PWRTVGCSGSIQASLALEAGVSMLPTF---WTAWSQQEQGAAGAGVRVALPQVEELGRHD 71

Query: 79  GGGISSYADNPSGASQSLV--GCLEQALQDVPKERHAGTPLYLGATAGMR 126
           GGG  + A       +  +  GC  +A   VP+ R  G+PL LG+    R
Sbjct: 72  GGGEEAQAQEAGDGDERYILEGC-GRARAGVPQTRAPGSPLPLGSVPDPR 120


>gi|5032105 small optic lobes [Homo sapiens]
          Length = 1086

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 5/75 (6%)

Query: 109 KERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVF 168
           + RHA + L +    G RLL L NP    S   + +     +P   RG  +  G  EGVF
Sbjct: 714 RPRHAYSILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVF 773

Query: 169 GWVTANYLLENFIKY 183
            W+       +F++Y
Sbjct: 774 -WMEYG----DFVRY 783


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,280,075
Number of Sequences: 37866
Number of extensions: 805759
Number of successful extensions: 1739
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1675
Number of HSP's gapped (non-prelim): 21
length of query: 472
length of database: 18,247,518
effective HSP length: 106
effective length of query: 366
effective length of database: 14,233,722
effective search space: 5209542252
effective search space used: 5209542252
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.